Result of FASTA (ccds) for
pFN21AE1474
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1474, 502 aa
1>>>pF1KE1474 502 - 502 aa - 502 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8688+/-0.000884; mu= 20.4844+/- 0.053
mean_var=62.8745+/-12.334, 0's: 0 Z-trim(106.0): 16 B-trim: 3 in 1/50
Lambda= 0.161747
statistics sampled from 8738 (8744) to 8738 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.269), width: 16
Scan time: 3.190
The best scores are: opt bits E(32554)
CCDS2874.1 IL17RB gene_id:55540|Hs108|chr3 ( 502) 3442 812.0 0
CCDS77645.1 IL17RA gene_id:23765|Hs108|chr22 ( 832) 337 87.6 5.7e-17
CCDS13739.1 IL17RA gene_id:23765|Hs108|chr22 ( 866) 302 79.5 1.7e-14
>>CCDS2874.1 IL17RB gene_id:55540|Hs108|chr3 (502 aa)
initn: 3442 init1: 3442 opt: 3442 Z-score: 4337.1 bits: 812.0 E(32554): 0
Smith-Waterman score: 3442; 100.0% identity (100.0% similar) in 502 aa overlap (1-502:1-502)
10 20 30 40 50 60
pF1KE1 MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 DYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 FSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 DPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 DPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 GDSEGATVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 GDSEGATVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ATWVLVAGIYLMWRHERIKKTSFSTTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 ATWVLVAGIYLMWRHERIKKTSFSTTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHCR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 SEVILEKWQKKKIAEMGPVQWLATQKKAADKVVFLLSNDVNSVCDGTCGKSEGSPSENSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 SEVILEKWQKKKIAEMGPVQWLATQKKAADKVVFLLSNDVNSVCDGTCGKSEGSPSENSQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 DLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDYNALSVCPKYHLMKDATAFCAELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 DLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDYNALSVCPKYHLMKDATAFCAELL
430 440 450 460 470 480
490 500
pF1KE1 HVKQQVSAGKRSQACHDGCCSL
::::::::::::::::::::::
CCDS28 HVKQQVSAGKRSQACHDGCCSL
490 500
>>CCDS77645.1 IL17RA gene_id:23765|Hs108|chr22 (832 aa)
initn: 342 init1: 134 opt: 337 Z-score: 418.1 bits: 87.6 E(32554): 5.7e-17
Smith-Waterman score: 507; 24.8% identity (53.5% similar) in 488 aa overlap (13-469:39-492)
10 20 30 40
pF1KE1 MSLVLLSLAALCRSAVPREPTVQCGSETGP--SPEWMLQHDL
:. : .: ..: ... . :. ..:
CCDS77 SAVPGPLLGLLLLLLGVLAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 IPGDLRDLRVEPVTTSVATGDYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCV
:.. .::... . . :: . .. :.:..:::: :..... : . : . ::
CCDS77 TPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVL-QLNTNERLCV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 RCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSP
: . : .. : .: :.. : :. . : . .:..:. . : .: :: :
CCDS77 RFE----FLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNFLVP
130 140 150 160 170 180
170 180 190 200 210
pF1KE1 GCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYMALI-------QH
: :: :...:::::::::. . . ..:.:: ...:. :. .:
CCDS77 DCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENH
190 200 210 220 230 240
220 230 240 250 260
pF1KE1 STIIGFSQVFEPHQKK-QTRASVVIPVTGDSEGAT---VQLTPYFPTCGSDCIRHKGTVV
: . . .. :. .. . :..:.. . . .: ::. :.: .: .::.::..::
CCDS77 SCFEHMHHIPAPRPEEFHQRSNVTLTLR-NLKGCCRHQVQIQPFFSSCLNDCLRHSATVS
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE1 LCPQT-GVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHERIKKTSFSTTTL
::. .: :. . ::. . . .. .. :
CCDS77 -CPEMPDTPEPIPG----PGSE---------------------KYSDDTKYTDGLPAADL
310 320 330
330 340 350 360 370 380
pF1KE1 LPPI----KVLVVYPSEICFH-HTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLA
.:: :: ..: .. .. .. :..:: . : .:: :. ... :.: : . :..
CCDS77 IPPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAGVMTWVG
340 350 360 370 380 390
390 400 410 420 430
pF1KE1 TQKK----AADKVVFLLSNDVNSVCDGTCGKSEGSP-------SENSQDLFPLAFNLFCS
::. . .:.. : : . . .. :. :.: .. ::: :.:..
CCDS77 RQKQEMVESNSKIIVLCSRGTRAKWQALLGR--GAPVRLRCDHGKPVGDLFTAAMNMILP
400 410 420 430 440 450
440 450 460 470 480 490
pF1KE1 DLRSQIHLHKYVVVYFREIDTKDDYNAL-SVCPKYHLMKDATAFCAELLHVKQQVSAGKR
:.. . ::: :: :.. : : .. :.: ::
CCDS77 DFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLEMFQPGRMH
460 470 480 490 500 510
500
pF1KE1 SQACHDGCCSL
CCDS77 RVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQDAPSLDEEVFEE
520 530 540 550 560 570
>>CCDS13739.1 IL17RA gene_id:23765|Hs108|chr22 (866 aa)
initn: 351 init1: 134 opt: 302 Z-score: 373.7 bits: 79.5 E(32554): 1.7e-14
Smith-Waterman score: 563; 25.7% identity (54.6% similar) in 498 aa overlap (13-469:39-526)
10 20 30 40
pF1KE1 MSLVLLSLAALCRSAVPREPTVQCGSETGP--SPEWMLQHDL
:. : .: ..: ... . :. ..:
CCDS13 SAVPGPLLGLLLLLLGVLAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 IPGDLRDLRVEPVTTSVATGDYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCV
:.. .::... . . :: . .. :.:..:::: :..... : . : . ::
CCDS13 TPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVL-QLNTNERLCV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 RCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSP
: . : .. : .: :.. : :. . : . .:..:. . : .: :: :
CCDS13 RFE----FLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNFLVP
130 140 150 160 170 180
170 180 190 200 210
pF1KE1 GCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYMALI-------QH
: :: :...:::::::::. . . ..:.:: ...:. :. .:
CCDS13 DCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENH
190 200 210 220 230 240
220 230 240 250 260
pF1KE1 STIIGFSQVFEPHQKK-QTRASVVIPVTGDSEGAT---VQLTPYFPTCGSDCIRHKGTVV
: . . .. :. .. . :..:.. . . .: ::. :.: .: .::.::..::
CCDS13 SCFEHMHHIPAPRPEEFHQRSNVTLTLR-NLKGCCRHQVQIQPFFSSCLNDCLRHSATVS
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE1 LCPQT-GVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHERIKKTSFSTTT-
::. .: :. . :. . :::.. .:. . . :: . ..: :
CCDS13 -CPEMPDTPEPIPDYMPLWVYWFITGISILLVGSVILLI-VCMTWRLAGPGSEKYSDDTK
310 320 330 340 350 360
330 340 350 360 370
pF1KE1 ---------LLPPI----KVLVVYPSEICFH-HTICYFTEFLQNHCRSEVILEKWQKKKI
:.:: :: ..: .. .. .. :..:: . : .:: :. ... :
CCDS13 YTDGLPAADLIPPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAI
370 380 390 400 410 420
380 390 400 410 420
pF1KE1 AEMGPVQWLATQKK----AADKVVFLLSNDVNSVCDGTCGKSEGSP-------SENSQDL
.: : . :.. ::. . .:.. : : . . .. :. :.: .. ::
CCDS13 SEAGVMTWVGRQKQEMVESNSKIIVLCSRGTRAKWQALLGR--GAPVRLRCDHGKPVGDL
430 440 450 460 470
430 440 450 460 470 480
pF1KE1 FPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDYNAL-SVCPKYHLMKDATAFCAELLH
: :.:.. :.. . ::: :: :.. : : .. :.: ::
CCDS13 FTAAMNMILPDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQD
480 490 500 510 520 530
490 500
pF1KE1 VKQQVSAGKRSQACHDGCCSL
CCDS13 LEMFQPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQDA
540 550 560 570 580 590
502 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 15:42:50 2016 done: Mon Nov 7 15:42:50 2016
Total Scan time: 3.190 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]