Result of FASTA (omim) for
pFN21AE1473
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1473, 381 aa
1>>>pF1KE1473 381 - 381 aa - 381 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6731+/-0.000317; mu= 11.1952+/- 0.020
mean_var=120.3104+/-24.427, 0's: 0 Z-trim(119.5): 180 B-trim: 439 in 1/60
Lambda= 0.116929
statistics sampled from 33497 (33698) to 33497 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.395), width: 16
Scan time: 7.780
The best scores are: opt bits E(85289)
NP_000565 (OMIM: 125240,613793) complement decay-a ( 381) 2632 454.7 1.6e-127
XP_016855956 (OMIM: 125240,613793) PREDICTED: comp ( 412) 2512 434.5 2.1e-121
NP_001108224 (OMIM: 125240,613793) complement deca ( 440) 2512 434.5 2.2e-121
NP_001287831 (OMIM: 125240,613793) complement deca ( 444) 2512 434.5 2.2e-121
NP_001287833 (OMIM: 125240,613793) complement deca ( 384) 2497 432.0 1.1e-120
NP_001287832 (OMIM: 125240,613793) complement deca ( 439) 2497 432.0 1.3e-120
NP_783641 (OMIM: 605886) complement component rece ( 569) 549 103.5 1.3e-21
NP_000564 (OMIM: 120620,607486,611162) complement (2039) 552 104.4 2.5e-21
XP_006711229 (OMIM: 120620,607486,611162) PREDICTE (2459) 552 104.5 2.9e-21
NP_000642 (OMIM: 120620,607486,611162) complement (2489) 552 104.5 2.9e-21
XP_011507507 (OMIM: 120620,607486,611162) PREDICTE (2554) 552 104.5 3e-21
XP_005273309 (OMIM: 120830) PREDICTED: C4b-binding ( 597) 541 102.1 3.5e-21
XP_005273308 (OMIM: 120830) PREDICTED: C4b-binding ( 597) 541 102.1 3.5e-21
NP_000706 (OMIM: 120830) C4b-binding protein alpha ( 597) 541 102.1 3.5e-21
NP_001868 (OMIM: 120650,240500,610927,614699) comp (1033) 450 87.0 2.2e-16
NP_001006659 (OMIM: 120650,240500,610927,614699) c (1092) 450 87.0 2.3e-16
NP_699197 (OMIM: 611691) sushi, von Willebrand fac (3571) 429 83.8 6.8e-15
XP_011533056 (OMIM: 608397) PREDICTED: CUB and sus (2238) 424 82.8 8.5e-15
XP_011533055 (OMIM: 608397) PREDICTED: CUB and sus (2595) 424 82.9 9.5e-15
XP_016869220 (OMIM: 608397) PREDICTED: CUB and sus (3327) 424 83.0 1.2e-14
XP_011533054 (OMIM: 608397) PREDICTED: CUB and sus (3549) 424 83.0 1.2e-14
NP_150094 (OMIM: 608397) CUB and sushi domain-cont (3564) 424 83.0 1.2e-14
XP_011507508 (OMIM: 120650,240500,610927,614699) P ( 969) 412 80.5 1.8e-14
XP_016856799 (OMIM: 120920,612922) PREDICTED: memb ( 348) 402 78.5 2.6e-14
NP_758860 (OMIM: 120920,612922) membrane cofactor ( 349) 402 78.5 2.6e-14
NP_758871 (OMIM: 120920,612922) membrane cofactor ( 355) 402 78.5 2.6e-14
NP_758862 (OMIM: 120920,612922) membrane cofactor ( 362) 402 78.5 2.7e-14
XP_016856798 (OMIM: 120920,612922) PREDICTED: memb ( 363) 402 78.5 2.7e-14
NP_758863 (OMIM: 120920,612922) membrane cofactor ( 369) 402 78.5 2.7e-14
XP_011507866 (OMIM: 120920,612922) PREDICTED: memb ( 370) 402 78.5 2.7e-14
NP_758861 (OMIM: 120920,612922) membrane cofactor ( 377) 402 78.6 2.8e-14
XP_016856797 (OMIM: 120920,612922) PREDICTED: memb ( 378) 402 78.6 2.8e-14
NP_722548 (OMIM: 120920,612922) membrane cofactor ( 384) 402 78.6 2.8e-14
XP_011507865 (OMIM: 120920,612922) PREDICTED: memb ( 385) 402 78.6 2.8e-14
NP_002380 (OMIM: 120920,612922) membrane cofactor ( 392) 402 78.6 2.8e-14
NP_758869 (OMIM: 120920,612922) membrane cofactor ( 399) 402 78.6 2.9e-14
NP_000033 (OMIM: 138700) beta-2-glycoprotein 1 pre ( 345) 374 73.8 6.8e-13
NP_001107571 (OMIM: 616667) seizure 6-like protein ( 840) 366 72.7 3.5e-12
NP_963869 (OMIM: 616667) seizure 6-like protein 2 ( 910) 366 72.8 3.7e-12
XP_016878624 (OMIM: 616667) PREDICTED: seizure 6-l ( 739) 362 72.0 5e-12
NP_001107572 (OMIM: 616667) seizure 6-like protein ( 809) 362 72.0 5.4e-12
NP_036542 (OMIM: 616667) seizure 6-like protein 2 ( 853) 362 72.1 5.6e-12
NP_001230262 (OMIM: 616667) seizure 6-like protein ( 879) 362 72.1 5.7e-12
NP_001230261 (OMIM: 616667) seizure 6-like protein ( 923) 362 72.1 6e-12
XP_016855679 (OMIM: 608398) PREDICTED: CUB and sus (3362) 359 72.0 2.3e-11
NP_443128 (OMIM: 608398) CUB and sushi domain-cont (3487) 359 72.0 2.4e-11
XP_016855678 (OMIM: 608398) PREDICTED: CUB and sus (3506) 359 72.0 2.4e-11
XP_016855683 (OMIM: 608398) PREDICTED: CUB and sus (3566) 359 72.0 2.4e-11
XP_016855677 (OMIM: 608398) PREDICTED: CUB and sus (3567) 359 72.0 2.4e-11
XP_016855676 (OMIM: 608398) PREDICTED: CUB and sus (3606) 359 72.0 2.5e-11
>>NP_000565 (OMIM: 125240,613793) complement decay-accel (381 aa)
initn: 2632 init1: 2632 opt: 2632 Z-score: 2410.5 bits: 454.7 E(85289): 1.6e-127
Smith-Waterman score: 2632; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:1-381)
10 20 30 40 50 60
pF1KE1 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS
310 320 330 340 350 360
370 380
pF1KE1 GHTCFTLTGLLGTLVTMGLLT
:::::::::::::::::::::
NP_000 GHTCFTLTGLLGTLVTMGLLT
370 380
>>XP_016855956 (OMIM: 125240,613793) PREDICTED: compleme (412 aa)
initn: 2505 init1: 2505 opt: 2512 Z-score: 2300.6 bits: 434.5 E(85289): 2.1e-121
Smith-Waterman score: 2512; 98.1% identity (98.6% similar) in 370 aa overlap (1-370:1-370)
10 20 30 40 50 60
pF1KE1 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS
310 320 330 340 350 360
370 380
pF1KE1 GHTCFTLTGLLGTLVTMGLLT
: : .:.
XP_016 GSRPVTQAGMRWCDRSSLQSRTPGFKRSFHFSLPSSWYYRFLSMEEEKTRGI
370 380 390 400 410
>>NP_001108224 (OMIM: 125240,613793) complement decay-ac (440 aa)
initn: 2505 init1: 2505 opt: 2512 Z-score: 2300.2 bits: 434.5 E(85289): 2.2e-121
Smith-Waterman score: 2512; 98.1% identity (98.6% similar) in 370 aa overlap (1-370:1-370)
10 20 30 40 50 60
pF1KE1 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS
310 320 330 340 350 360
370 380
pF1KE1 GHTCFTLTGLLGTLVTMGLLT
: : .:.
NP_001 GSRPVTQAGMRWCDRSSLQSRTPGFKRSFHFSLPSSWYYRAHVFHVDRFAWDASNHGLAD
370 380 390 400 410 420
>>NP_001287831 (OMIM: 125240,613793) complement decay-ac (444 aa)
initn: 2505 init1: 2505 opt: 2512 Z-score: 2300.1 bits: 434.5 E(85289): 2.2e-121
Smith-Waterman score: 2512; 98.1% identity (98.6% similar) in 370 aa overlap (1-370:1-370)
10 20 30 40 50 60
pF1KE1 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS
310 320 330 340 350 360
370 380
pF1KE1 GHTCFTLTGLLGTLVTMGLLT
: : .:.
NP_001 GSRPVTQAGMRWCDRSSLQSRTPGFKRSFHFSLPSSWYYRCVPRHPAKFLKFIFCRDRIF
370 380 390 400 410 420
>>NP_001287833 (OMIM: 125240,613793) complement decay-ac (384 aa)
initn: 2497 init1: 2497 opt: 2497 Z-score: 2287.3 bits: 432.0 E(85289): 1.1e-120
Smith-Waterman score: 2497; 100.0% identity (100.0% similar) in 360 aa overlap (1-360:1-360)
10 20 30 40 50 60
pF1KE1 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS
310 320 330 340 350 360
370 380
pF1KE1 GHTCFTLTGLLGTLVTMGLLT
NP_001 ALQVRPFEVSGSSHISSKKMMCIL
370 380
>>NP_001287832 (OMIM: 125240,613793) complement decay-ac (439 aa)
initn: 2497 init1: 2497 opt: 2497 Z-score: 2286.5 bits: 432.0 E(85289): 1.3e-120
Smith-Waterman score: 2497; 100.0% identity (100.0% similar) in 360 aa overlap (1-360:1-360)
10 20 30 40 50 60
pF1KE1 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS
310 320 330 340 350 360
370 380
pF1KE1 GHTCFTLTGLLGTLVTMGLLT
NP_001 ETVFHRVIQDGLDLLASRSACLGLPKCWDYRREPPHLARAHVFHVDRFAWDASNHGLADL
370 380 390 400 410 420
>>NP_783641 (OMIM: 605886) complement component receptor (569 aa)
initn: 435 init1: 304 opt: 549 Z-score: 509.0 bits: 103.5 E(85289): 1.3e-21
Smith-Waterman score: 555; 38.7% identity (63.0% similar) in 243 aa overlap (71-303:15-242)
50 60 70 80 90 100
pF1KE1 DVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEV
..:: ... : :..:: .:.:
NP_783 MAPPVRLERPFPSRRFPGLLLAALVLLLSSFSD-------QCNV
10 20 30
110 120 130 140 150
pF1KE1 PTRLNSASLKQPYITQNY-FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCK
: : : . .:... ::.:: ..::::::: .: .. ::.: :..: . ::
NP_783 PEWLPFA--RPTNLTDDFEFPIGTYLNYECRPGYSGRPF---SIICLKNSVWTSAKDKCK
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE1 KKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPE
.::: :: . ::. : : : . :..:: ::.:.::.:. :.:::..: :.. :
NP_783 RKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPV
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE1 CREIYCPAPPQIDNGIIQG-ERDHYGYRQSVTYACNKG------FTMIGEHSIYCTVNND
: .: : :: : :: . . :... : . ::: :: : : ..:: ::::: ..:
NP_783 CDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDD
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE1 E-GEWSGPPPECRGKSLTSK-VPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRS
. : :::: :.: . .: .::.:.. :.
NP_783 QVGIWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSH
220 230 240 250 260
340 350 360 370 380
pF1KE1 TPVSRTTKHFHETTPNKGSGTTSGTTRLLSGHTCFTLTGLLGTLVTMGLLT
NP_783 VKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTY
270 280 290 300 310 320
>--
initn: 367 init1: 283 opt: 449 Z-score: 417.8 bits: 86.6 E(85289): 1.6e-16
Smith-Waterman score: 483; 27.4% identity (57.0% similar) in 307 aa overlap (50-353:243-535)
20 30 40 50 60 70
pF1KE1 RLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESF-VKIPGEKDS
..:. : . :. ..:. .: .: :..
NP_783 QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSH---
220 230 240 250 260
80 90 100 110 120 130
pF1KE1 VICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPS
: : ..: :.: :. : . : : .. : : : : :.::: . :
NP_783 VKCQALNKWEPELPSCSRVCQPPPDVLHAERTQR--DKDNFSPGQEVFYSCEPGYDLRGS
270 280 290 300 310 320
140 150 160 170 180 190
pF1KE1 LSPKLTCLQNLKWSTAVEFCKKKSCPNP-GEIRNGQIDVPGGILFGATISFSCNTGYKLF
: : . :: :. :. ::: . :.. ::.. : .. .:: ..: :. :..:
NP_783 T--YLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLK
330 340 350 360 370 380
200 210 220 230 240 250
pF1KE1 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERD-HYGYRQSVTYACNKG
::..:.:...: :.. .: :.. : .:: ::... : : : : ..:.:. :
NP_783 GSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSR--INYSCTTG
390 400 410 420 430 440
260 270 280 290 300 310
pF1KE1 FTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKT
.::. : : .... ..:: :: : ... ::.. . ...: .. .. .
NP_783 HRLIGHSSAECILSGNTAHWSMKPPIC--QQIFCPNPPAILNGRHTGTPLGDIPYGKEVS
450 460 470 480 490 500
320 330 340 350 360 370
pF1KE1 TTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGHTCFTLTGLLGTLVT
: :. : . ....: ...:. .:.:. :
NP_783 YTCDPHPDRGMTFNL-IGEST--IRRTSEPHGNGVWSSPAPRCELPVGAGSHDALIVGKF
510 520 530 540 550
380
pF1KE1 MGLLT
NP_783 YEVFAEEFCHL
560
>>NP_000564 (OMIM: 120620,607486,611162) complement rece (2039 aa)
initn: 410 init1: 323 opt: 552 Z-score: 503.9 bits: 104.4 E(85289): 2.5e-21
Smith-Waterman score: 619; 36.7% identity (61.9% similar) in 289 aa overlap (36-303:421-700)
10 20 30 40 50 60
pF1KE1 PSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKC
: :: .::.. . . :: ...: :
NP_000 QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTC
400 410 420 430 440 450
70 80 90 100 110
pF1KE1 EE------SFVKIPGEKDSVICLKGSQ----WSDIEEFCN--RSCEVPTRLNSASLKQPY
. :: : ::. .. : . : ::. :. :..: .. :.::
NP_000 DPHPDRGTSFDLI-GES-TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQT
460 470 480 490 500
120 130 140 150 160 170
pF1KE1 ITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQ
... ::.:: ..::::: : .: ..:::.:: ::. . ::.::: .: . ::.
NP_000 NASD-FPIGTSLKYECRPEYYGRPF---SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGM
510 520 530 540 550 560
180 190 200 210 220 230
pF1KE1 IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDN
. : : :. :..::.::..:.: .:. :..::....:: : :..: : :: : :
NP_000 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIAN
570 580 590 600 610 620
240 250 260 270 280
pF1KE1 G-IIQGERDHYGYRQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPECRG
: .:. .:... : . ::: :: : : ..:: ::::: :.:. : :::: :.:
NP_000 GDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC--
630 640 650 660 670 680
290 300 310 320 330 340
pF1KE1 KSLTSK-VPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETT
. .: .::.:.. :.
NP_000 -IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP
690 700 710 720 730 740
>--
initn: 447 init1: 308 opt: 618 Z-score: 564.1 bits: 115.5 E(85289): 1.1e-24
Smith-Waterman score: 618; 36.7% identity (61.9% similar) in 289 aa overlap (36-303:871-1150)
10 20 30 40 50 60
pF1KE1 PSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKC
: :: .::.. . . :: ...: :
NP_000 QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTC
850 860 870 880 890 900
70 80 90 100 110
pF1KE1 EE------SFVKIPGEKDSVICLKGSQ----WSDIEEFCN--RSCEVPTRLNSASLKQPY
. :: : ::. .. : . : ::. :. :..: .. :.::
NP_000 DPHPDRGTSFDLI-GES-TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQT
910 920 930 940 950
120 130 140 150 160 170
pF1KE1 ITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQ
... ::.:: ..::::: : .: ..:::.:: ::. . ::.::: .: . ::.
NP_000 NASD-FPIGTSLKYECRPEYYGRPF---SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGM
960 970 980 990 1000 1010
180 190 200 210 220 230
pF1KE1 IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDN
. : : :. :..::.::..:.: .:. :..::....:: : :..: : :: : :
NP_000 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIAN
1020 1030 1040 1050 1060 1070
240 250 260 270 280
pF1KE1 G-IIQGERDHYGYRQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPECRG
: .:. .:... : . ::: :: : : ..:: ::::: :.:. : :::: :.:
NP_000 GDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC--
1080 1090 1100 1110 1120 1130
290 300 310 320 330 340
pF1KE1 KSLTSK-VPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETT
. .: .::.:.. :.
NP_000 -IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP
1140 1150 1160 1170 1180 1190
>--
initn: 541 init1: 321 opt: 577 Z-score: 526.7 bits: 108.6 E(85289): 1.3e-22
Smith-Waterman score: 577; 41.7% identity (66.7% similar) in 216 aa overlap (98-303:43-250)
70 80 90 100 110 120
pF1KE1 SFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNY-FPVGTVVE
:..: : : . .:... ::.:: ..
NP_000 GPPAPGLPFCCGGSLLAVVVLLALPVAWGQCNAPEWLPFA--RPTNLTDEFEFPIGTYLN
20 30 40 50 60 70
130 140 150 160 170 180
pF1KE1 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATI
::::::: .: .. ::.: :. : . :..::: :: . ::.. : :: ::. :
NP_000 YECRPGYSGRPF---SIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQI
80 90 100 110 120
190 200 210 220 230 240
pF1KE1 SFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGY
..::. ::.:.::.:. :.:::..: :.. : : .: : :: : :: .:. .:... :
NP_000 KYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHY
130 140 150 160 170 180
250 260 270 280 290
pF1KE1 RQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPECRGKSLTSK-VPPTVQ
. ::: :: : : ..:: ::::: :.:. : :::: :.: . .: .::.:.
NP_000 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC---IIPNKCTPPNVE
190 200 210 220 230 240
300 310 320 330 340 350
pF1KE1 KPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTR
. :.
NP_000 NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVL
250 260 270 280 290 300
>--
initn: 410 init1: 323 opt: 576 Z-score: 525.8 bits: 108.4 E(85289): 1.5e-22
Smith-Waterman score: 576; 34.0% identity (59.0% similar) in 288 aa overlap (36-299:1321-1603)
10 20 30 40 50 60
pF1KE1 PSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKC
: :: . :.. . ..: :.: :
NP_000 RLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTC
1300 1310 1320 1330 1340 1350
70 80 90 100 110
pF1KE1 EES-----FVKIPGEKDSVICLKGSQ----WSDIEEFCNRS-----CEVPTRLNSASLKQ
. .. ::. .. : . . ::. :. : :..: .. ::
NP_000 DPHPDRGMTFNLIGES-TIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTI
1360 1370 1380 1390 1400
120 130 140 150 160 170
pF1KE1 PYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRN
: :.. ::::: ..::::::: . ...::.:: ::.. . :..::: : : :
NP_000 P-INDFEFPVGTSLNYECRPGYFGKMF---SISCLENLVWSSVEDNCRRKSCGPPPEPFN
1410 1420 1430 1440 1450 1460
180 190 200 210 220 230
pF1KE1 GQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQI
:.. . ::.:...::: :..:.:: :. ::.::..: :. : :. : : :: :
NP_000 GMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTI
1470 1480 1490 1500 1510 1520
240 250 260 270 280
pF1KE1 DNG-IIQGERDHYGYRQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPEC
.:: . ...: . ::: :. : : ..::.::::: ..:. : ::.:::.:
NP_000 SNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC
1530 1540 1550 1560 1570 1580
290 300 310 320 330 340
pF1KE1 --RGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFH
.: . .: ... :
NP_000 ISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPH
1590 1600 1610 1620 1630 1640
>--
initn: 357 init1: 223 opt: 480 Z-score: 438.3 bits: 92.2 E(85289): 1.1e-17
Smith-Waterman score: 480; 30.6% identity (58.5% similar) in 258 aa overlap (52-297:1606-1855)
30 40 50 60 70 80
pF1KE1 LLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVIC
:. : .: ..:. .:: . .. .: :
NP_000 GVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSH--TVQC
1580 1590 1600 1610 1620 1630
90 100 110 120 130 140
pF1KE1 LKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSP
...:. :.: :. : .. . .. :. : : : : :.:.: . . :
NP_000 QTNGRWGPKLPHCSRVCQPPPEILHG--EHTLSHQDNFSPGQEVFYSCEPSYDLRGAAS-
1640 1650 1660 1670 1680 1690
150 160 170 180 190 200
pF1KE1 KLTCLQNLKWSTAVEFCKKKSCPNP-GEIRNGQIDVPGGILFGATISFSCNTGYKLFGST
: : . :: . : ::: . :.. .:.. .: .. .:: .:: :. :..: : .
NP_000 -LHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRS
1700 1710 1720 1730 1740
210 220 230 240 250
pF1KE1 SSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYG---YRQSVTYACN---
.: :...: .. :.. .: :..:.:: :: : :: : .: : . ..:::.
NP_000 ASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTG--TPFGDIPYGKEISYACDTHP
1750 1760 1770 1780 1790 1800
260 270 280 290 300
pF1KE1 -KG--FTMIGEHSIYCTVN-NDEGEWSGPPPECR-GKSLTSKVPPTVQKPTTVNVPTTEV
.: :..::: :: :: . . .: ::.: :.:. . . :: .:
NP_000 DRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLY
1810 1820 1830 1840 1850 1860
310 320 330 340 350 360
pF1KE1 SPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGHTCFTLTG
NP_000 LPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKV
1870 1880 1890 1900 1910 1920
>--
initn: 197 init1: 96 opt: 323 Z-score: 295.2 bits: 65.8 E(85289): 1.1e-09
Smith-Waterman score: 323; 29.5% identity (56.8% similar) in 176 aa overlap (50-224:1151-1320)
20 30 40 50 60 70
pF1KE1 RLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSV
..:. : . :. ..:. .:: . : . :
NP_000 QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPR-RV
1130 1140 1150 1160 1170
80 90 100 110 120 130
pF1KE1 ICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSL
: ..: :.: :. : .. . . : .:. : : : : :.::: . .
NP_000 KCQALNKWEPELPSCSRVCQPPPEILHGE-HTPSHQDNFSP-GQEVFYSCEPGYDLRGAA
1180 1190 1200 1210 1220 1230
140 150 160 170 180 190
pF1KE1 SPKLTCLQNLKWSTAVEFCKKKSCPNP-GEIRNGQIDVPGGILFGATISFSCNTGYKLFG
: : : . :: . : ::: . :.. .:.. : .. .:: .:: :. :..: :
NP_000 S--LHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKG
1240 1250 1260 1270 1280 1290
200 210 220 230 240 250
pF1KE1 STSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFT
:. : :.. : :.. .: :..:.
NP_000 SSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHP
1300 1310 1320 1330 1340 1350
>>XP_006711229 (OMIM: 120620,607486,611162) PREDICTED: c (2459 aa)
initn: 410 init1: 323 opt: 552 Z-score: 502.8 bits: 104.5 E(85289): 2.9e-21
Smith-Waterman score: 619; 36.7% identity (61.9% similar) in 289 aa overlap (36-303:876-1155)
10 20 30 40 50 60
pF1KE1 PSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKC
: :: .::.. . . :: ...: :
XP_006 QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTC
850 860 870 880 890 900
70 80 90 100 110
pF1KE1 EE------SFVKIPGEKDSVICLKGSQ----WSDIEEFCN--RSCEVPTRLNSASLKQPY
. :: : ::. .. : . : ::. :. :..: .. :.::
XP_006 DPHPDRGTSFDLI-GES-TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQT
910 920 930 940 950 960
120 130 140 150 160 170
pF1KE1 ITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQ
... ::.:: ..::::: : .: ..:::.:: ::. . ::.::: .: . ::.
XP_006 NASD-FPIGTSLKYECRPEYYGRPF---SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGM
970 980 990 1000 1010
180 190 200 210 220 230
pF1KE1 IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDN
. : : :. :..::.::..:.: .:. :..::....:: : :..: : :: : :
XP_006 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIAN
1020 1030 1040 1050 1060 1070
240 250 260 270 280
pF1KE1 G-IIQGERDHYGYRQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPECRG
: .:. .:... : . ::: :: : : ..:: ::::: :.:. : :::: :.:
XP_006 GDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC--
1080 1090 1100 1110 1120 1130
290 300 310 320 330 340
pF1KE1 KSLTSK-VPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETT
. .: .::.:.. :.
XP_006 -IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP
1140 1150 1160 1170 1180 1190
>--
initn: 516 init1: 307 opt: 619 Z-score: 563.9 bits: 115.8 E(85289): 1.1e-24
Smith-Waterman score: 619; 36.7% identity (61.9% similar) in 289 aa overlap (36-303:426-705)
10 20 30 40 50 60
pF1KE1 PSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKC
: :: .::.. . . :: ...: :
XP_006 QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTC
400 410 420 430 440 450
70 80 90 100 110
pF1KE1 EE------SFVKIPGEKDSVICLKGSQ----WSDIEEFCN--RSCEVPTRLNSASLKQPY
. :: : ::. .. : . : ::. :. :..: .. :.::
XP_006 DPHPDRGTSFDLI-GES-TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQT
460 470 480 490 500 510
120 130 140 150 160 170
pF1KE1 ITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQ
... ::.:: ..::::: : .: ..:::.:: ::. . ::.::: .: . ::.
XP_006 NASD-FPIGTSLKYECRPEYYGRPF---SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGM
520 530 540 550 560
180 190 200 210 220 230
pF1KE1 IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDN
. : : :. :..::.::..:.: .:. :..::....:: : :..: : :: : :
XP_006 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIAN
570 580 590 600 610 620
240 250 260 270 280
pF1KE1 G-IIQGERDHYGYRQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPECRG
: .:. .:... : . ::: :: : : ..:: ::::: :.:. : :::: :.:
XP_006 GDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC--
630 640 650 660 670 680
290 300 310 320 330 340
pF1KE1 KSLTSK-VPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETT
. .: .::.:.. :.
XP_006 -IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP
690 700 710 720 730 740
>--
initn: 376 init1: 308 opt: 618 Z-score: 563.0 bits: 115.6 E(85289): 1.3e-24
Smith-Waterman score: 618; 36.7% identity (61.9% similar) in 289 aa overlap (36-303:1326-1605)
10 20 30 40 50 60
pF1KE1 PSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKC
: :: .::.. . . :: ...: :
XP_006 QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTC
1300 1310 1320 1330 1340 1350
70 80 90 100 110
pF1KE1 EE------SFVKIPGEKDSVICLKGSQ----WSDIEEFCN--RSCEVPTRLNSASLKQPY
. :: : ::. .. : . : ::. :. :..: .. :.::
XP_006 DPHPDRGTSFDLI-GES-TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQT
1360 1370 1380 1390 1400 1410
120 130 140 150 160 170
pF1KE1 ITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQ
... ::.:: ..::::: : .: ..:::.:: ::. . ::.::: .: . ::.
XP_006 NASD-FPIGTSLKYECRPEYYGRPF---SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGM
1420 1430 1440 1450 1460
180 190 200 210 220 230
pF1KE1 IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDN
. : : :. :..::.::..:.: .:. :..::....:: : :..: : :: : :
XP_006 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIAN
1470 1480 1490 1500 1510 1520
240 250 260 270 280
pF1KE1 G-IIQGERDHYGYRQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPECRG
: .:. .:... : . ::: :: : : ..:: ::::: :.:. : :::: :.:
XP_006 GDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC--
1530 1540 1550 1560 1570 1580
290 300 310 320 330 340
pF1KE1 KSLTSK-VPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETT
. .: .::.:.. :.
XP_006 -IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP
1590 1600 1610 1620 1630 1640
>--
initn: 408 init1: 321 opt: 577 Z-score: 525.6 bits: 108.7 E(85289): 1.5e-22
Smith-Waterman score: 577; 41.7% identity (66.7% similar) in 216 aa overlap (98-303:48-255)
70 80 90 100 110 120
pF1KE1 SFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNY-FPVGTVVE
:..: : : . .:... ::.:: ..
XP_006 GPPAPGLPFCCGGSLLAVVVLLALPVAWGQCNAPEWLPFA--RPTNLTDEFEFPIGTYLN
20 30 40 50 60 70
130 140 150 160 170 180
pF1KE1 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATI
::::::: .: .. ::.: :. : . :..::: :: . ::.. : :: ::. :
XP_006 YECRPGYSGRPF---SIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQI
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE1 SFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGY
..::. ::.:.::.:. :.:::..: :.. : : .: : :: : :: .:. .:... :
XP_006 KYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHY
140 150 160 170 180 190
250 260 270 280 290
pF1KE1 RQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPECRGKSLTSK-VPPTVQ
. ::: :: : : ..:: ::::: :.:. : :::: :.: . .: .::.:.
XP_006 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC---IIPNKCTPPNVE
200 210 220 230 240
300 310 320 330 340 350
pF1KE1 KPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTR
. :.
XP_006 NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVL
250 260 270 280 290 300
>--
initn: 410 init1: 323 opt: 576 Z-score: 524.7 bits: 108.5 E(85289): 1.7e-22
Smith-Waterman score: 576; 34.0% identity (59.0% similar) in 288 aa overlap (36-299:1776-2058)
10 20 30 40 50 60
pF1KE1 PSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKC
: :: . :.. . ..: :.: :
XP_006 RLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTC
1750 1760 1770 1780 1790 1800
70 80 90 100 110
pF1KE1 EES-----FVKIPGEKDSVICLKGSQ----WSDIEEFCNRS-----CEVPTRLNSASLKQ
. .. ::. .. : . . ::. :. : :..: .. ::
XP_006 DPHPDRGMTFNLIGES-TIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTI
1810 1820 1830 1840 1850 1860
120 130 140 150 160 170
pF1KE1 PYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRN
: :.. ::::: ..::::::: . ...::.:: ::.. . :..::: : : :
XP_006 P-INDFEFPVGTSLNYECRPGYFGKMF---SISCLENLVWSSVEDNCRRKSCGPPPEPFN
1870 1880 1890 1900 1910 1920
180 190 200 210 220 230
pF1KE1 GQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQI
:.. . ::.:...::: :..:.:: :. ::.::..: :. : :. : : :: :
XP_006 GMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTI
1930 1940 1950 1960 1970 1980
240 250 260 270 280
pF1KE1 DNG-IIQGERDHYGYRQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPEC
.:: . ...: . ::: :. : : ..::.::::: ..:. : ::.:::.:
XP_006 SNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC
1990 2000 2010 2020 2030 2040
290 300 310 320 330 340
pF1KE1 --RGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFH
.: . .: ... :
XP_006 ISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPH
2050 2060 2070 2080 2090 2100
>--
initn: 357 init1: 223 opt: 480 Z-score: 437.1 bits: 92.3 E(85289): 1.3e-17
Smith-Waterman score: 480; 30.6% identity (58.5% similar) in 258 aa overlap (52-297:2061-2310)
30 40 50 60 70 80
pF1KE1 LLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVIC
:. : .: ..:. .:: . .. .: :
XP_006 GVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSH--TVQC
2040 2050 2060 2070 2080
90 100 110 120 130 140
pF1KE1 LKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSP
...:. :.: :. : .. . .. :. : : : : :.:.: . . :
XP_006 QTNGRWGPKLPHCSRVCQPPPEILHG--EHTLSHQDNFSPGQEVFYSCEPSYDLRGAAS-
2090 2100 2110 2120 2130 2140
150 160 170 180 190 200
pF1KE1 KLTCLQNLKWSTAVEFCKKKSCPNP-GEIRNGQIDVPGGILFGATISFSCNTGYKLFGST
: : . :: . : ::: . :.. .:.. .: .. .:: .:: :. :..: : .
XP_006 -LHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRS
2150 2160 2170 2180 2190 2200
210 220 230 240 250
pF1KE1 SSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYG---YRQSVTYACN---
.: :...: .. :.. .: :..:.:: :: : :: : .: : . ..:::.
XP_006 ASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTG--TPFGDIPYGKEISYACDTHP
2210 2220 2230 2240 2250 2260
260 270 280 290 300
pF1KE1 -KG--FTMIGEHSIYCTVN-NDEGEWSGPPPECR-GKSLTSKVPPTVQKPTTVNVPTTEV
.: :..::: :: :: . . .: ::.: :.:. . . :: .:
XP_006 DRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLY
2270 2280 2290 2300 2310 2320
310 320 330 340 350 360
pF1KE1 SPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGHTCFTLTG
XP_006 LPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKV
2330 2340 2350 2360 2370 2380
>--
initn: 197 init1: 96 opt: 323 Z-score: 294.0 bits: 65.8 E(85289): 1.2e-09
Smith-Waterman score: 323; 29.5% identity (56.8% similar) in 176 aa overlap (50-224:1606-1775)
20 30 40 50 60 70
pF1KE1 RLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSV
..:. : . :. ..:. .:: . : . :
XP_006 QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPR-RV
1580 1590 1600 1610 1620 1630
80 90 100 110 120 130
pF1KE1 ICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSL
: ..: :.: :. : .. . . : .:. : : : : :.::: . .
XP_006 KCQALNKWEPELPSCSRVCQPPPEILHGE-HTPSHQDNFSP-GQEVFYSCEPGYDLRGAA
1640 1650 1660 1670 1680 1690
140 150 160 170 180 190
pF1KE1 SPKLTCLQNLKWSTAVEFCKKKSCPNP-GEIRNGQIDVPGGILFGATISFSCNTGYKLFG
: : : . :: . : ::: . :.. .:.. : .. .:: .:: :. :..: :
XP_006 S--LHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKG
1700 1710 1720 1730 1740
200 210 220 230 240 250
pF1KE1 STSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFT
:. : :.. : :.. .: :..:.
XP_006 SSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHP
1750 1760 1770 1780 1790 1800
>>NP_000642 (OMIM: 120620,607486,611162) complement rece (2489 aa)
initn: 410 init1: 323 opt: 552 Z-score: 502.7 bits: 104.5 E(85289): 2.9e-21
Smith-Waterman score: 619; 36.7% identity (61.9% similar) in 289 aa overlap (36-303:871-1150)
10 20 30 40 50 60
pF1KE1 PSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKC
: :: .::.. . . :: ...: :
NP_000 QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTC
850 860 870 880 890 900
70 80 90 100 110
pF1KE1 EE------SFVKIPGEKDSVICLKGSQ----WSDIEEFCN--RSCEVPTRLNSASLKQPY
. :: : ::. .. : . : ::. :. :..: .. :.::
NP_000 DPHPDRGTSFDLI-GES-TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQT
910 920 930 940 950
120 130 140 150 160 170
pF1KE1 ITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQ
... ::.:: ..::::: : .: ..:::.:: ::. . ::.::: .: . ::.
NP_000 NASD-FPIGTSLKYECRPEYYGRPF---SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGM
960 970 980 990 1000 1010
180 190 200 210 220 230
pF1KE1 IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDN
. : : :. :..::.::..:.: .:. :..::....:: : :..: : :: : :
NP_000 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIAN
1020 1030 1040 1050 1060 1070
240 250 260 270 280
pF1KE1 G-IIQGERDHYGYRQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPECRG
: .:. .:... : . ::: :: : : ..:: ::::: :.:. : :::: :.:
NP_000 GDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC--
1080 1090 1100 1110 1120 1130
290 300 310 320 330 340
pF1KE1 KSLTSK-VPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETT
. .: .::.:.. :.
NP_000 -IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP
1140 1150 1160 1170 1180 1190
>--
initn: 516 init1: 307 opt: 619 Z-score: 563.8 bits: 115.8 E(85289): 1.2e-24
Smith-Waterman score: 619; 36.7% identity (61.9% similar) in 289 aa overlap (36-303:421-700)
10 20 30 40 50 60
pF1KE1 PSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKC
: :: .::.. . . :: ...: :
NP_000 QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTC
400 410 420 430 440 450
70 80 90 100 110
pF1KE1 EE------SFVKIPGEKDSVICLKGSQ----WSDIEEFCN--RSCEVPTRLNSASLKQPY
. :: : ::. .. : . : ::. :. :..: .. :.::
NP_000 DPHPDRGTSFDLI-GES-TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQT
460 470 480 490 500
120 130 140 150 160 170
pF1KE1 ITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQ
... ::.:: ..::::: : .: ..:::.:: ::. . ::.::: .: . ::.
NP_000 NASD-FPIGTSLKYECRPEYYGRPF---SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGM
510 520 530 540 550 560
180 190 200 210 220 230
pF1KE1 IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDN
. : : :. :..::.::..:.: .:. :..::....:: : :..: : :: : :
NP_000 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIAN
570 580 590 600 610 620
240 250 260 270 280
pF1KE1 G-IIQGERDHYGYRQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPECRG
: .:. .:... : . ::: :: : : ..:: ::::: :.:. : :::: :.:
NP_000 GDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC--
630 640 650 660 670 680
290 300 310 320 330 340
pF1KE1 KSLTSK-VPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETT
. .: .::.:.. :.
NP_000 -IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP
690 700 710 720 730 740
>--
initn: 376 init1: 308 opt: 618 Z-score: 562.9 bits: 115.6 E(85289): 1.3e-24
Smith-Waterman score: 618; 36.7% identity (61.9% similar) in 289 aa overlap (36-303:1321-1600)
10 20 30 40 50 60
pF1KE1 PSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKC
: :: .::.. . . :: ...: :
NP_000 QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTC
1300 1310 1320 1330 1340 1350
70 80 90 100 110
pF1KE1 EE------SFVKIPGEKDSVICLKGSQ----WSDIEEFCN--RSCEVPTRLNSASLKQPY
. :: : ::. .. : . : ::. :. :..: .. :.::
NP_000 DPHPDRGTSFDLI-GES-TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQT
1360 1370 1380 1390 1400
120 130 140 150 160 170
pF1KE1 ITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQ
... ::.:: ..::::: : .: ..:::.:: ::. . ::.::: .: . ::.
NP_000 NASD-FPIGTSLKYECRPEYYGRPF---SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGM
1410 1420 1430 1440 1450 1460
180 190 200 210 220 230
pF1KE1 IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDN
. : : :. :..::.::..:.: .:. :..::....:: : :..: : :: : :
NP_000 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIAN
1470 1480 1490 1500 1510 1520
240 250 260 270 280
pF1KE1 G-IIQGERDHYGYRQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPECRG
: .:. .:... : . ::: :: : : ..:: ::::: :.:. : :::: :.:
NP_000 GDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC--
1530 1540 1550 1560 1570 1580
290 300 310 320 330 340
pF1KE1 KSLTSK-VPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETT
. .: .::.:.. :.
NP_000 -IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP
1590 1600 1610 1620 1630 1640
>--
initn: 408 init1: 321 opt: 577 Z-score: 525.5 bits: 108.7 E(85289): 1.6e-22
Smith-Waterman score: 577; 41.7% identity (66.7% similar) in 216 aa overlap (98-303:43-250)
70 80 90 100 110 120
pF1KE1 SFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNY-FPVGTVVE
:..: : : . .:... ::.:: ..
NP_000 GPPAPGLPFCCGGSLLAVVVLLALPVAWGQCNAPEWLPFA--RPTNLTDEFEFPIGTYLN
20 30 40 50 60 70
130 140 150 160 170 180
pF1KE1 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATI
::::::: .: .. ::.: :. : . :..::: :: . ::.. : :: ::. :
NP_000 YECRPGYSGRPF---SIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQI
80 90 100 110 120
190 200 210 220 230 240
pF1KE1 SFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGY
..::. ::.:.::.:. :.:::..: :.. : : .: : :: : :: .:. .:... :
NP_000 KYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHY
130 140 150 160 170 180
250 260 270 280 290
pF1KE1 RQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPECRGKSLTSK-VPPTVQ
. ::: :: : : ..:: ::::: :.:. : :::: :.: . .: .::.:.
NP_000 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC---IIPNKCTPPNVE
190 200 210 220 230 240
300 310 320 330 340 350
pF1KE1 KPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTR
. :.
NP_000 NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVL
250 260 270 280 290 300
>--
initn: 410 init1: 323 opt: 576 Z-score: 524.6 bits: 108.5 E(85289): 1.8e-22
Smith-Waterman score: 576; 34.0% identity (59.0% similar) in 288 aa overlap (36-299:1771-2053)
10 20 30 40 50 60
pF1KE1 PSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKC
: :: . :.. . ..: :.: :
NP_000 RLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTC
1750 1760 1770 1780 1790 1800
70 80 90 100 110
pF1KE1 EES-----FVKIPGEKDSVICLKGSQ----WSDIEEFCNRS-----CEVPTRLNSASLKQ
. .. ::. .. : . . ::. :. : :..: .. ::
NP_000 DPHPDRGMTFNLIGES-TIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTI
1810 1820 1830 1840 1850
120 130 140 150 160 170
pF1KE1 PYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRN
: :.. ::::: ..::::::: . ...::.:: ::.. . :..::: : : :
NP_000 P-INDFEFPVGTSLNYECRPGYFGKMF---SISCLENLVWSSVEDNCRRKSCGPPPEPFN
1860 1870 1880 1890 1900 1910
180 190 200 210 220 230
pF1KE1 GQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQI
:.. . ::.:...::: :..:.:: :. ::.::..: :. : :. : : :: :
NP_000 GMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTI
1920 1930 1940 1950 1960 1970
240 250 260 270 280
pF1KE1 DNG-IIQGERDHYGYRQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPEC
.:: . ...: . ::: :. : : ..::.::::: ..:. : ::.:::.:
NP_000 SNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC
1980 1990 2000 2010 2020 2030
290 300 310 320 330 340
pF1KE1 --RGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFH
.: . .: ... :
NP_000 ISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPH
2040 2050 2060 2070 2080 2090
>--
initn: 357 init1: 223 opt: 480 Z-score: 437.1 bits: 92.3 E(85289): 1.3e-17
Smith-Waterman score: 480; 30.6% identity (58.5% similar) in 258 aa overlap (52-297:2056-2305)
30 40 50 60 70 80
pF1KE1 LLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVIC
:. : .: ..:. .:: . .. .: :
NP_000 GVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSH--TVQC
2030 2040 2050 2060 2070 2080
90 100 110 120 130 140
pF1KE1 LKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSP
...:. :.: :. : .. . .. :. : : : : :.:.: . . :
NP_000 QTNGRWGPKLPHCSRVCQPPPEILHG--EHTLSHQDNFSPGQEVFYSCEPSYDLRGAAS-
2090 2100 2110 2120 2130 2140
150 160 170 180 190 200
pF1KE1 KLTCLQNLKWSTAVEFCKKKSCPNP-GEIRNGQIDVPGGILFGATISFSCNTGYKLFGST
: : . :: . : ::: . :.. .:.. .: .. .:: .:: :. :..: : .
NP_000 -LHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRS
2150 2160 2170 2180 2190
210 220 230 240 250
pF1KE1 SSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYG---YRQSVTYACN---
.: :...: .. :.. .: :..:.:: :: : :: : .: : . ..:::.
NP_000 ASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTG--TPFGDIPYGKEISYACDTHP
2200 2210 2220 2230 2240 2250
260 270 280 290 300
pF1KE1 -KG--FTMIGEHSIYCTVN-NDEGEWSGPPPECR-GKSLTSKVPPTVQKPTTVNVPTTEV
.: :..::: :: :: . . .: ::.: :.:. . . :: .:
NP_000 DRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLY
2260 2270 2280 2290 2300 2310
310 320 330 340 350 360
pF1KE1 SPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGHTCFTLTG
NP_000 LPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKV
2320 2330 2340 2350 2360 2370
>--
initn: 197 init1: 96 opt: 323 Z-score: 293.9 bits: 65.8 E(85289): 1.2e-09
Smith-Waterman score: 323; 29.5% identity (56.8% similar) in 176 aa overlap (50-224:1601-1770)
20 30 40 50 60 70
pF1KE1 RLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSV
..:. : . :. ..:. .:: . : . :
NP_000 QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPR-RV
1580 1590 1600 1610 1620
80 90 100 110 120 130
pF1KE1 ICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSL
: ..: :.: :. : .. . . : .:. : : : : :.::: . .
NP_000 KCQALNKWEPELPSCSRVCQPPPEILHGE-HTPSHQDNFSP-GQEVFYSCEPGYDLRGAA
1630 1640 1650 1660 1670 1680
140 150 160 170 180 190
pF1KE1 SPKLTCLQNLKWSTAVEFCKKKSCPNP-GEIRNGQIDVPGGILFGATISFSCNTGYKLFG
: : : . :: . : ::: . :.. .:.. : .. .:: .:: :. :..: :
NP_000 S--LHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKG
1690 1700 1710 1720 1730 1740
200 210 220 230 240 250
pF1KE1 STSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFT
:. : :.. : :.. .: :..:.
NP_000 SSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHP
1750 1760 1770 1780 1790 1800
381 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:51:40 2016 done: Mon Nov 7 02:51:41 2016
Total Scan time: 7.780 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]