Result of FASTA (omim) for
pFN21AE1463
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1463, 150 aa
1>>>pF1KE1463 150 - 150 aa - 150 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9550+/-0.000307; mu= 12.9528+/- 0.019
mean_var=53.2126+/-10.629, 0's: 0 Z-trim(116.3): 29 B-trim: 30 in 1/52
Lambda= 0.175820
statistics sampled from 27318 (27347) to 27318 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.703), E-opt: 0.2 (0.321), width: 16
Scan time: 5.450
The best scores are: opt bits E(85289)
NP_665874 (OMIM: 246530,614037) leukotriene C4 syn ( 150) 964 251.9 2.9e-67
XP_016863702 (OMIM: 601733) PREDICTED: microsomal ( 147) 408 110.8 8.1e-25
XP_016863701 (OMIM: 601733) PREDICTED: microsomal ( 147) 408 110.8 8.1e-25
NP_002404 (OMIM: 601733) microsomal glutathione S- ( 147) 408 110.8 8.1e-25
XP_016863700 (OMIM: 601733) PREDICTED: microsomal ( 147) 408 110.8 8.1e-25
NP_001191295 (OMIM: 601733) microsomal glutathione ( 147) 408 110.8 8.1e-25
NP_001620 (OMIM: 601367,603700) arachidonate 5-lip ( 161) 255 72.0 4.2e-13
NP_001191335 (OMIM: 601367,603700) arachidonate 5- ( 218) 255 72.1 5.5e-13
NP_001191297 (OMIM: 601733) microsomal glutathione ( 77) 182 53.4 8.4e-08
XP_016876011 (OMIM: 601367,603700) PREDICTED: arac ( 121) 174 51.4 5.1e-07
XP_006714284 (OMIM: 601733) PREDICTED: microsomal ( 79) 146 44.3 4.8e-05
NP_001191296 (OMIM: 601733) microsomal glutathione ( 79) 146 44.3 4.8e-05
XP_016863703 (OMIM: 601733) PREDICTED: microsomal ( 79) 146 44.3 4.8e-05
XP_011530274 (OMIM: 601733) PREDICTED: microsomal ( 79) 146 44.3 4.8e-05
XP_005245231 (OMIM: 604564) PREDICTED: microsomal ( 152) 135 41.6 0.00059
NP_004519 (OMIM: 604564) microsomal glutathione S- ( 152) 135 41.6 0.00059
>>NP_665874 (OMIM: 246530,614037) leukotriene C4 synthas (150 aa)
initn: 964 init1: 964 opt: 964 Z-score: 1328.6 bits: 251.9 E(85289): 2.9e-67
Smith-Waterman score: 964; 99.3% identity (100.0% similar) in 150 aa overlap (1-150:1-150)
10 20 30 40 50 60
pF1KE1 MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 PLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVA
70 80 90 100 110 120
130 140 150
pF1KE1 LAALGLLAHFLPAALRAALLGQLRTLLPWA
:::::::::::::::::::::.::::::::
NP_665 LAALGLLAHFLPAALRAALLGRLRTLLPWA
130 140 150
>>XP_016863702 (OMIM: 601733) PREDICTED: microsomal glut (147 aa)
initn: 406 init1: 406 opt: 408 Z-score: 566.5 bits: 110.8 E(85289): 8.1e-25
Smith-Waterman score: 408; 45.1% identity (70.8% similar) in 144 aa overlap (1-144:1-144)
10 20 30 40 50 60
pF1KE1 MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYF
: . :::::..:.. :.::.::: .:: ..:.:: .:: ::::::.::: :: :..
XP_016 MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGSPEFERVFRAQQNCVEFY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVA
:.:. :::.:: .:.. :. ::::...: :: ::...:. :.. . : : ::.
XP_016 PIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGYSEAAKKRITGFRLSLGILALLTL
70 80 90 100 110 120
130 140 150
pF1KE1 LAALGLLAHFLPAALRAALLGQLRTLLPWA
:.:::. :: : . .::
XP_016 LGALGIANSFLDEYLDLNIAKKLRRQF
130 140
>>XP_016863701 (OMIM: 601733) PREDICTED: microsomal glut (147 aa)
initn: 406 init1: 406 opt: 408 Z-score: 566.5 bits: 110.8 E(85289): 8.1e-25
Smith-Waterman score: 408; 45.1% identity (70.8% similar) in 144 aa overlap (1-144:1-144)
10 20 30 40 50 60
pF1KE1 MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYF
: . :::::..:.. :.::.::: .:: ..:.:: .:: ::::::.::: :: :..
XP_016 MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGSPEFERVFRAQQNCVEFY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVA
:.:. :::.:: .:.. :. ::::...: :: ::...:. :.. . : : ::.
XP_016 PIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGYSEAAKKRITGFRLSLGILALLTL
70 80 90 100 110 120
130 140 150
pF1KE1 LAALGLLAHFLPAALRAALLGQLRTLLPWA
:.:::. :: : . .::
XP_016 LGALGIANSFLDEYLDLNIAKKLRRQF
130 140
>>NP_002404 (OMIM: 601733) microsomal glutathione S-tran (147 aa)
initn: 406 init1: 406 opt: 408 Z-score: 566.5 bits: 110.8 E(85289): 8.1e-25
Smith-Waterman score: 408; 45.1% identity (70.8% similar) in 144 aa overlap (1-144:1-144)
10 20 30 40 50 60
pF1KE1 MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYF
: . :::::..:.. :.::.::: .:: ..:.:: .:: ::::::.::: :: :..
NP_002 MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGSPEFERVFRAQQNCVEFY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVA
:.:. :::.:: .:.. :. ::::...: :: ::...:. :.. . : : ::.
NP_002 PIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGYSEAAKKRITGFRLSLGILALLTL
70 80 90 100 110 120
130 140 150
pF1KE1 LAALGLLAHFLPAALRAALLGQLRTLLPWA
:.:::. :: : . .::
NP_002 LGALGIANSFLDEYLDLNIAKKLRRQF
130 140
>>XP_016863700 (OMIM: 601733) PREDICTED: microsomal glut (147 aa)
initn: 406 init1: 406 opt: 408 Z-score: 566.5 bits: 110.8 E(85289): 8.1e-25
Smith-Waterman score: 408; 45.1% identity (70.8% similar) in 144 aa overlap (1-144:1-144)
10 20 30 40 50 60
pF1KE1 MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYF
: . :::::..:.. :.::.::: .:: ..:.:: .:: ::::::.::: :: :..
XP_016 MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGSPEFERVFRAQQNCVEFY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVA
:.:. :::.:: .:.. :. ::::...: :: ::...:. :.. . : : ::.
XP_016 PIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGYSEAAKKRITGFRLSLGILALLTL
70 80 90 100 110 120
130 140 150
pF1KE1 LAALGLLAHFLPAALRAALLGQLRTLLPWA
:.:::. :: : . .::
XP_016 LGALGIANSFLDEYLDLNIAKKLRRQF
130 140
>>NP_001191295 (OMIM: 601733) microsomal glutathione S-t (147 aa)
initn: 406 init1: 406 opt: 408 Z-score: 566.5 bits: 110.8 E(85289): 8.1e-25
Smith-Waterman score: 408; 45.1% identity (70.8% similar) in 144 aa overlap (1-144:1-144)
10 20 30 40 50 60
pF1KE1 MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYF
: . :::::..:.. :.::.::: .:: ..:.:: .:: ::::::.::: :: :..
NP_001 MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGSPEFERVFRAQQNCVEFY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVA
:.:. :::.:: .:.. :. ::::...: :: ::...:. :.. . : : ::.
NP_001 PIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGYSEAAKKRITGFRLSLGILALLTL
70 80 90 100 110 120
130 140 150
pF1KE1 LAALGLLAHFLPAALRAALLGQLRTLLPWA
:.:::. :: : . .::
NP_001 LGALGIANSFLDEYLDLNIAKKLRRQF
130 140
>>NP_001620 (OMIM: 601367,603700) arachidonate 5-lipoxyg (161 aa)
initn: 253 init1: 240 opt: 255 Z-score: 356.2 bits: 72.0 E(85289): 4.2e-13
Smith-Waterman score: 255; 36.7% identity (64.1% similar) in 128 aa overlap (5-131:9-135)
10 20 30 40 50
pF1KE1 MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNC
:.::: :::..:. ...:. .: :. :: ::::: :. ::
NP_001 MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 SEYFPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYA-SARAL
. .: :::.:: ::.. . ::. ::.:::.: .:: :: . . . .: : . : .
NP_001 VDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYL-GERTQSTPGYIFGKRII
70 80 90 100 110
120 130 140 150
pF1KE1 WLLVALAALGLLAHFLPAALRAALLGQLRTLLPWA
.: ... :.. ..:
NP_001 LFLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
120 130 140 150 160
>>NP_001191335 (OMIM: 601367,603700) arachidonate 5-lipo (218 aa)
initn: 240 init1: 240 opt: 255 Z-score: 354.1 bits: 72.1 E(85289): 5.5e-13
Smith-Waterman score: 255; 36.7% identity (64.1% similar) in 128 aa overlap (5-131:66-192)
10 20 30
pF1KE1 MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFR
:.::: :::..:. ...:. .: :.
NP_001 HQCWAGCAAGGRAVLSGEPEANMDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQN
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE1 VSPPLTTGPPEFERVYRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYF
:: ::::: :. :: . .: :::.:: ::.. . ::. ::.:::.: .::
NP_001 GRSFQRTGTLAFERVYTANQNCVDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYF
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE1 QGYARSAQLRLAPLYA-SARALWLLVALAALGLLAHFLPAALRAALLGQLRTLLPWA
:: . . . .: : . : . .: ... :.. ..:
NP_001 VGYL-GERTQSTPGYIFGKRIILFLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPL
160 170 180 190 200 210
NP_001 LLIP
>>NP_001191297 (OMIM: 601733) microsomal glutathione S-t (77 aa)
initn: 190 init1: 179 opt: 182 Z-score: 261.1 bits: 53.4 E(85289): 8.4e-08
Smith-Waterman score: 182; 43.2% identity (70.3% similar) in 74 aa overlap (1-74:1-71)
10 20 30 40 50 60
pF1KE1 MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYF
: . :::::..:.. :.::.::: .:: ..:.:: .:: ::::::.::. : :.
NP_001 MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGSPEFERVFRAHF-C--YL
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 PLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVA
. .: . :..
NP_001 SGSGVHIWPSPILLGIFRSC
60 70
>>XP_016876011 (OMIM: 601367,603700) PREDICTED: arachido (121 aa)
initn: 172 init1: 159 opt: 174 Z-score: 247.1 bits: 51.4 E(85289): 5.1e-07
Smith-Waterman score: 174; 35.9% identity (66.7% similar) in 78 aa overlap (55-131:19-95)
30 40 50 60 70 80
pF1KE1 QVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGL
:: . .: :::.:: ::.. . ::. ::
XP_016 MRLQEEKNMHLILLSENQNCVDAYPTFLAVLWSAGLLCSQVPAAFAGL
10 20 30 40
90 100 110 120 130 140
pF1KE1 VYLFARLRYFQGYARSAQLRLAPLYA-SARALWLLVALAALGLLAHFLPAALRAALLGQL
.:::.: .:: :: . . . .: : . : . .: ... :.. ..:
XP_016 MYLFVRQKYFVGYL-GERTQSTPGYIFGKRIILFLFLMSVAGIFNYYLIFFFGSDFENYI
50 60 70 80 90 100
150
pF1KE1 RTLLPWA
XP_016 KTISTTISPLLLIP
110 120
150 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:17:11 2016 done: Mon Nov 7 00:17:12 2016
Total Scan time: 5.450 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]