Result of FASTA (ccds) for
pFN21AE1452
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1452, 249 aa
1>>>pF1KE1452 249 - 249 aa - 249 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2421+/-0.000809; mu= 6.8000+/- 0.049
mean_var=131.5305+/-25.672, 0's: 0 Z-trim(112.2): 10 B-trim: 0 in 0/55
Lambda= 0.111831
statistics sampled from 13025 (13034) to 13025 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.757), E-opt: 0.2 (0.4), width: 16
Scan time: 2.350
The best scores are: opt bits E(32554)
CCDS9612.1 PSME1 gene_id:5720|Hs108|chr14 ( 249) 1634 274.2 6e-74
CCDS61415.1 PSME1 gene_id:5720|Hs108|chr14 ( 233) 1468 247.4 6.5e-66
CCDS41930.1 PSME1 gene_id:5720|Hs108|chr14 ( 250) 1468 247.4 6.9e-66
CCDS45689.1 PSME3 gene_id:10197|Hs108|chr17 ( 254) 679 120.1 1.5e-27
CCDS59290.1 PSME3 gene_id:10197|Hs108|chr17 ( 265) 657 116.5 1.8e-26
CCDS9614.1 PSME2 gene_id:5721|Hs108|chr14 ( 239) 547 98.8 3.6e-21
CCDS82133.1 PSME3 gene_id:10197|Hs108|chr17 ( 193) 498 90.8 7.2e-19
CCDS11442.1 PSME3 gene_id:10197|Hs108|chr17 ( 267) 396 74.4 8.5e-14
>>CCDS9612.1 PSME1 gene_id:5720|Hs108|chr14 (249 aa)
initn: 1634 init1: 1634 opt: 1634 Z-score: 1441.1 bits: 274.2 E(32554): 6e-74
Smith-Waterman score: 1634; 100.0% identity (100.0% similar) in 249 aa overlap (1-249:1-249)
10 20 30 40 50 60
pF1KE1 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS96 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS96 LDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS96 IKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEKLKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS96 RGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEKLKKP
190 200 210 220 230 240
pF1KE1 RGETKGMIY
:::::::::
CCDS96 RGETKGMIY
>>CCDS61415.1 PSME1 gene_id:5720|Hs108|chr14 (233 aa)
initn: 1468 init1: 1468 opt: 1468 Z-score: 1296.8 bits: 247.4 E(32554): 6.5e-66
Smith-Waterman score: 1468; 100.0% identity (100.0% similar) in 223 aa overlap (1-223:1-223)
10 20 30 40 50 60
pF1KE1 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 LDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 IKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEKLKKP
:::::::::::::::::::::::::::::::::::::::::::
CCDS61 RGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYVRRLCYMTSS
190 200 210 220 230
pF1KE1 RGETKGMIY
>>CCDS41930.1 PSME1 gene_id:5720|Hs108|chr14 (250 aa)
initn: 1468 init1: 1468 opt: 1468 Z-score: 1296.4 bits: 247.4 E(32554): 6.9e-66
Smith-Waterman score: 1468; 100.0% identity (100.0% similar) in 223 aa overlap (1-223:1-223)
10 20 30 40 50 60
pF1KE1 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 LDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 IKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEKLKKP
:::::::::::::::::::::::::::::::::::::::::::
CCDS41 RGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYVRRQGQGRGGQRQLSQA
190 200 210 220 230 240
pF1KE1 RGETKGMIY
CCDS41 THSLTLQARG
250
>>CCDS45689.1 PSME3 gene_id:10197|Hs108|chr17 (254 aa)
initn: 672 init1: 473 opt: 679 Z-score: 608.3 bits: 120.1 E(32554): 1.5e-27
Smith-Waterman score: 679; 40.9% identity (74.2% similar) in 252 aa overlap (2-249:3-254)
10 20 30 40 50
pF1KE1 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKA
..:.:. :.. ::: ::: . ...:.:....::::. :::.::::: :: .:.....
CCDS45 MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 PLDIPVPDPVKEKEKEE--RKKQQEKEDKDEKKKGEDEDKG--PPCGPVNCNEKIVVLLQ
...:::::. .... .:. :: ... . : : : .. :...: ...
CCDS45 DMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 RLKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQIS
..::::. .::. : : :.:: ::::::::::::..::.. . ..... .. :::
CCDS45 KVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQIS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 KYFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFE
.:. :. :.: :: ::: :::. : :.:: :: ..::.. :.:: :..:.:.::::.:
CCDS45 RYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIE
190 200 210 220 230 240
240
pF1KE1 KLKKPRGETKGMIY
:.:.::. . .:
CCDS45 KIKRPRSSNAETLY
250
>>CCDS59290.1 PSME3 gene_id:10197|Hs108|chr17 (265 aa)
initn: 672 init1: 473 opt: 657 Z-score: 588.8 bits: 116.5 E(32554): 1.8e-26
Smith-Waterman score: 657; 41.5% identity (73.9% similar) in 241 aa overlap (13-249:25-265)
10 20 30 40
pF1KE1 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPA
::: ::: . ...:.:....::::. :::.:::::
CCDS59 MEKWILKKIKYLQSGGLSASYYSYKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPI
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 LNEANLSNLKAPLDIPVPDPVKEKEKEE--RKKQQEKEDKDEKKKGEDEDKG--PPCGPV
:: .:..... ...:::::. .... .:. :: ... . : : : .
CCDS59 LNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGML
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 NCNEKIVVLLQRLKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLH
. :...: .....::::. .::. : : :.:: ::::::::::::..::.. . ...
CCDS59 KSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVE
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE1 TKLEGFHTQISKYFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYA
.. .. :::.:. :. :.: :: ::: :::. : :.:: :: ..::.. :.:: :.
CCDS59 SEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYV
190 200 210 220 230 240
230 240
pF1KE1 VLYDIILKNFEKLKKPRGETKGMIY
.:.:.::::.::.:.::. . .:
CCDS59 TLHDMILKNIEKIKRPRSSNAETLY
250 260
>>CCDS9614.1 PSME2 gene_id:5721|Hs108|chr14 (239 aa)
initn: 763 init1: 536 opt: 547 Z-score: 493.6 bits: 98.8 E(32554): 3.6e-21
Smith-Waterman score: 736; 48.0% identity (74.0% similar) in 246 aa overlap (4-249:7-239)
10 20 30 40 50
pF1KE1 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNL
.:.. ::. .:.:::..: ..:..: ..:.:: :. .:.: .:: :.:..:
CCDS96 MAKPCGVRLSGEARKQVEVFRQNLFQEAEEFLYRFLPQKIIYLNQLLQEDSLNVADLTSL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 KAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRL
.::::::.::: . .. : ::..:: . :: . :::.. :: .
CCDS96 RAPLDIPIPDPPPKDDEMETDKQEKKEVHK-------------CGFLPGNEKVLSLLALV
70 80 90 100
120 130 140 150 160 170
pF1KE1 KPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKY
:::. . :. :: ::.: ::.:::::.::::.::::.: .....::.:.:.: ::::
CCDS96 KPEVWTLKEKCILVITWIQHLIPKIEDGNDFGVAIQEKVLERVNAVKTKVEAFQTTISKY
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 FSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEKL
::::::::.::.:. :: ::: :::: ::: : ..: ::...: :: :: :: .:.::.
CCDS96 FSERGDAVAKASKETHVMDYRALVHERDEAAYGELRAMVLDLRAFYAELYHIISSNLEKI
170 180 190 200 210 220
240
pF1KE1 KKPRGETKGMIY
.:.:: : .:
CCDS96 VNPKGEEKPSMY
230
>>CCDS82133.1 PSME3 gene_id:10197|Hs108|chr17 (193 aa)
initn: 506 init1: 473 opt: 498 Z-score: 452.2 bits: 90.8 E(32554): 7.2e-19
Smith-Waterman score: 498; 39.9% identity (71.5% similar) in 193 aa overlap (61-249:1-193)
40 50 60 70 80
pF1KE1 SYFPKKISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEE--RKKQQEKEDKDE
...:::::. .... .:. ::
CCDS82 MNLPVPDPILLTNSHDGLDGPTYKKRRLDE
10 20 30
90 100 110 120 130 140
pF1KE1 KKKGEDEDKG--PPCGPVNCNEKIVVLLQRLKPEIKDVIEQLNLVTTWLQLQIPRIEDGN
... . : : : .. :...: .....::::. .::. : : :.:: ::::::::
CCDS82 CEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGN
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 NFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSERGDAVTKAAKQPHVGDYRQLVHELDE
::::..::.. . ..... .. :::.:. :. :.: :: ::: :::. : :.::
CCDS82 NFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDE
100 110 120 130 140 150
210 220 230 240
pF1KE1 AEYRDIRLMVMEIRNAYAVLYDIILKNFEKLKKPRGETKGMIY
:: ..::.. :.:: :..:.:.::::.::.:.::. . .:
CCDS82 KEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY
160 170 180 190
>>CCDS11442.1 PSME3 gene_id:10197|Hs108|chr17 (267 aa)
initn: 644 init1: 392 opt: 396 Z-score: 361.2 bits: 74.4 E(32554): 8.5e-14
Smith-Waterman score: 643; 38.9% identity (70.6% similar) in 265 aa overlap (2-249:3-267)
10 20 30 40 50
pF1KE1 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKA
..:.:. :.. ::: ::: . ...:.:....::::. :::.::::: :: .:.....
CCDS11 MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 PLDIPVPDPVKEKEKEE--RKKQQEKEDKDEKKKGEDEDKG--PPCGPVNCNEKIVVLLQ
...:::::. .... .:. :: ... . : : : .. :...: ...
CCDS11 DMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIE
70 80 90 100 110 120
120 130 140 150 160
pF1KE1 RLKPEIKDVIEQLNL-------------VTTWLQLQIPRIEDGNNFGVAVQEKVFELMTS
..::::. .::. : : :.:: ::::::::::::..::.. . .
CCDS11 KVKPEIRLLIEKCNTPSGKGPHICFDLQVKMWVQLLIPRIEDGNNFGVSIQEETVAELRT
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE1 LHTKLEGFHTQISKYFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNA
.... .. :::.:. :. :.: :: ::: :::. : :.:: :: ..::.. :.::
CCDS11 VESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQ
190 200 210 220 230 240
230 240
pF1KE1 YAVLYDIILKNFEKLKKPRGETKGMIY
:..:.:.::::.::.:.::. . .:
CCDS11 YVTLHDMILKNIEKIKRPRSSNAETLY
250 260
249 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:06:19 2016 done: Mon Nov 7 03:06:20 2016
Total Scan time: 2.350 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]