Result of FASTA (omim) for
pFN21AE1450
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1450, 428 aa
1>>>pF1KE1450 428 - 428 aa - 428 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.3964+/-0.000534; mu= -1.5219+/- 0.033
mean_var=355.2670+/-76.767, 0's: 0 Z-trim(116.9): 134 B-trim: 37 in 1/54
Lambda= 0.068045
statistics sampled from 28301 (28442) to 28301 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.684), E-opt: 0.2 (0.333), width: 16
Scan time: 9.990
The best scores are: opt bits E(85289)
NP_443178 (OMIM: 607496) nostrin isoform 1 [Homo s ( 428) 2740 283.4 7.4e-76
NP_001165103 (OMIM: 607496) nostrin isoform 3 [Hom ( 478) 2740 283.5 7.9e-76
NP_001034813 (OMIM: 607496) nostrin isoform 2 [Hom ( 506) 2740 283.5 8.2e-76
XP_016858767 (OMIM: 607496) PREDICTED: nostrin iso ( 485) 2438 253.9 6.7e-67
XP_011508845 (OMIM: 607496) PREDICTED: nostrin iso ( 381) 1932 204.1 5.2e-52
XP_016858768 (OMIM: 607496) PREDICTED: nostrin iso ( 485) 1932 204.2 6.1e-52
XP_005246327 (OMIM: 607496) PREDICTED: nostrin iso ( 542) 1932 204.2 6.5e-52
NP_001165102 (OMIM: 607496) nostrin isoform 4 [Hom ( 563) 1932 204.3 6.7e-52
XP_016858769 (OMIM: 607496) PREDICTED: nostrin iso ( 324) 1915 202.3 1.5e-51
XP_011508842 (OMIM: 607496) PREDICTED: nostrin iso ( 521) 1630 174.6 5.3e-43
XP_006712296 (OMIM: 607496) PREDICTED: nostrin iso ( 542) 1630 174.6 5.5e-43
>>NP_443178 (OMIM: 607496) nostrin isoform 1 [Homo sapie (428 aa)
initn: 2740 init1: 2740 opt: 2740 Z-score: 1482.9 bits: 283.4 E(85289): 7.4e-76
Smith-Waterman score: 2740; 99.8% identity (99.8% similar) in 428 aa overlap (1-428:1-428)
10 20 30 40 50 60
pF1KE1 MKSTADLHQKLGKAIELEAIKPTYQVLNVQEKKRKSLDNEVEKTANLVISNWNQQIKAKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 MKSTADLHQKLGKAIELEAIKPTYQVLNVQEKKRKSLDNEVEKTANLVISNWNQQIKAKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KLMVSTKKHEALFQLVESSKQSMTEKEKRKLLNKLTKSTEKLEKEDENYYQKNMAGYSTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 KLMVSTKKHEALFQLVESSKQSMTEKEKRKLLNKLTKSTEKLEKEDENYYQKNMAGYSTR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 LKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 KDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 KDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 DKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 DKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 PSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 PSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 SSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGHFPAAYVEELPSN
:::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
NP_443 SSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEGGWWFGSLNGKKGHFPAAYVEELPSN
370 380 390 400 410 420
pF1KE1 AGNTATKA
::::::::
NP_443 AGNTATKA
>>NP_001165103 (OMIM: 607496) nostrin isoform 3 [Homo sa (478 aa)
initn: 2740 init1: 2740 opt: 2740 Z-score: 1482.3 bits: 283.5 E(85289): 7.9e-76
Smith-Waterman score: 2740; 99.8% identity (99.8% similar) in 428 aa overlap (1-428:51-478)
10 20 30
pF1KE1 MKSTADLHQKLGKAIELEAIKPTYQVLNVQ
::::::::::::::::::::::::::::::
NP_001 SQNGENFCKQVTSVLQQSCVSSAWAWASEGMKSTADLHQKLGKAIELEAIKPTYQVLNVQ
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE1 EKKRKSLDNEVEKTANLVISNWNQQIKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKKRKSLDNEVEKTANLVISNWNQQIKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRK
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE1 LLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLN
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE1 QYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE1 PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAAL
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE1 MDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLM
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE1 KRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH
390 400 410 420 430 440
400 410 420
pF1KE1 EKKEEGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA
:::: :::::::::::::::::::::::::::::::::
NP_001 EKKEGGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA
450 460 470
>>NP_001034813 (OMIM: 607496) nostrin isoform 2 [Homo sa (506 aa)
initn: 2740 init1: 2740 opt: 2740 Z-score: 1482.0 bits: 283.5 E(85289): 8.2e-76
Smith-Waterman score: 2740; 99.8% identity (99.8% similar) in 428 aa overlap (1-428:79-506)
10 20 30
pF1KE1 MKSTADLHQKLGKAIELEAIKPTYQVLNVQ
::::::::::::::::::::::::::::::
NP_001 LQKLASKLSKALQNTRKSCVSSAWAWASEGMKSTADLHQKLGKAIELEAIKPTYQVLNVQ
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE1 EKKRKSLDNEVEKTANLVISNWNQQIKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKKRKSLDNEVEKTANLVISNWNQQIKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRK
110 120 130 140 150 160
100 110 120 130 140 150
pF1KE1 LLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLN
170 180 190 200 210 220
160 170 180 190 200 210
pF1KE1 QYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
230 240 250 260 270 280
220 230 240 250 260 270
pF1KE1 PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAAL
290 300 310 320 330 340
280 290 300 310 320 330
pF1KE1 MDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLM
350 360 370 380 390 400
340 350 360 370 380 390
pF1KE1 KRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH
410 420 430 440 450 460
400 410 420
pF1KE1 EKKEEGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA
:::: :::::::::::::::::::::::::::::::::
NP_001 EKKEGGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA
470 480 490 500
>>XP_016858767 (OMIM: 607496) PREDICTED: nostrin isoform (485 aa)
initn: 2438 init1: 2438 opt: 2438 Z-score: 1322.0 bits: 253.9 E(85289): 6.7e-67
Smith-Waterman score: 2438; 100.0% identity (100.0% similar) in 383 aa overlap (1-383:79-461)
10 20 30
pF1KE1 MKSTADLHQKLGKAIELEAIKPTYQVLNVQ
::::::::::::::::::::::::::::::
XP_016 LQKLASKLSKALQNTRKSCVSSAWAWASEGMKSTADLHQKLGKAIELEAIKPTYQVLNVQ
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE1 EKKRKSLDNEVEKTANLVISNWNQQIKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKKRKSLDNEVEKTANLVISNWNQQIKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRK
110 120 130 140 150 160
100 110 120 130 140 150
pF1KE1 LLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLN
170 180 190 200 210 220
160 170 180 190 200 210
pF1KE1 QYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED
230 240 250 260 270 280
220 230 240 250 260 270
pF1KE1 PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAAL
290 300 310 320 330 340
280 290 300 310 320 330
pF1KE1 MDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLM
350 360 370 380 390 400
340 350 360 370 380 390
pF1KE1 KRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIH
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKERKLLRK
410 420 430 440 450 460
400 410 420
pF1KE1 EKKEEGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA
XP_016 RVKGRLKNHLRMMPNKK
470 480
>>XP_011508845 (OMIM: 607496) PREDICTED: nostrin isoform (381 aa)
initn: 1932 init1: 1932 opt: 1932 Z-score: 1054.8 bits: 204.1 E(85289): 5.2e-52
Smith-Waterman score: 1932; 99.3% identity (99.3% similar) in 299 aa overlap (130-428:83-381)
100 110 120 130 140 150
pF1KE1 EKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLF
: ::::::::::::::::::::::::::::
XP_011 YQDTFLPGNLPPLWFGYDIVKRLIMRLCSVCLQSILELEKERIQLLCNNLNQYSQHISLF
60 70 80 90 100 110
160 170 180 190 200 210
pF1KE1 GQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKER
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE1 RKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLD
180 190 200 210 220 230
280 290 300 310 320 330
pF1KE1 LLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSK
240 250 260 270 280 290
340 350 360 370 380 390
pF1KE1 ASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEEGWWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_011 ASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEGGWWF
300 310 320 330 340 350
400 410 420
pF1KE1 GSLNGKKGHFPAAYVEELPSNAGNTATKA
:::::::::::::::::::::::::::::
XP_011 GSLNGKKGHFPAAYVEELPSNAGNTATKA
360 370 380
>>XP_016858768 (OMIM: 607496) PREDICTED: nostrin isoform (485 aa)
initn: 1932 init1: 1932 opt: 1932 Z-score: 1053.6 bits: 204.2 E(85289): 6.1e-52
Smith-Waterman score: 2460; 87.4% identity (87.4% similar) in 460 aa overlap (26-428:26-485)
10 20 30 40 50 60
pF1KE1 MKSTADLHQKLGKAIELEAIKPTYQVLNVQEKKRKSLDNEVEKTANLVISNWNQQIKAKK
:::::::::::::::::::::::::::::::::::
XP_016 MKSTADLHQKLGKAIELEAIKPTYQVLNVQEKKRKSLDNEVEKTANLVISNWNQQIKAKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KLMVSTKKHEALFQLVESSKQSMTEKEKRKLLNKLTKSTEKLEKEDENYYQKNMAGYSTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLMVSTKKHEALFQLVESSKQSMTEKEKRKLLNKLTKSTEKLEKEDENYYQKNMAGYSTR
70 80 90 100 110 120
130
pF1KE1 LKWENTLENCYQ------------------------------------------------
::::::::::::
XP_016 LKWENTLENCYQVTHSICLYAFWVKRAWGKCVSDLRYQDTFLPGNLPPLWFGYDIVKRLI
130 140 150 160 170 180
140 150 160 170 180
pF1KE1 ---------SILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDI
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRLCSVCLQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDI
190 200 210 220 230 240
190 200 210 220 230 240
pF1KE1 QAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKE
250 260 270 280 290 300
250 260 270 280 290 300
pF1KE1 GLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSH
310 320 330 340 350 360
310 320 330 340 350 360
pF1KE1 PCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSR
370 380 390 400 410 420
370 380 390 400 410 420
pF1KE1 LCKALYSFQARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGHFPAAYVEELPSNAGN
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_016 LCKALYSFQARQDDELNLEKGDIVIIHEKKEGGWWFGSLNGKKGHFPAAYVEELPSNAGN
430 440 450 460 470 480
pF1KE1 TATKA
:::::
XP_016 TATKA
>>XP_005246327 (OMIM: 607496) PREDICTED: nostrin isoform (542 aa)
initn: 2139 init1: 1932 opt: 1932 Z-score: 1053.0 bits: 204.2 E(85289): 6.5e-52
Smith-Waterman score: 2407; 83.6% identity (83.6% similar) in 481 aa overlap (5-428:83-542)
10 20 30
pF1KE1 MKSTADLHQKLGKAIELEAIKPTYQVLNVQEKKR
::::::::::::::::::::::::::::::
XP_005 ASKLSKALQNTRKSCVSSAWAWASEGMKSTADLHQKLGKAIELEAIKPTYQVLNVQEKKR
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE1 KSLDNEVEKTANLVISNWNQQIKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRKLLNK
:: :::::::::::::::::::::::::::::::::::::
XP_005 KS---------------------AKKKLMVSTKKHEALFQLVESSKQSMTEKEKRKLLNK
120 130 140 150
100 110 120 130
pF1KE1 LTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQ----------------------
::::::::::::::::::::::::::::::::::::::
XP_005 LTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQVTHSICLYAFWVKRAWGKCVSD
160 170 180 190 200 210
140 150
pF1KE1 -----------------------------------SILELEKERIQLLCNNLNQYSQHIS
:::::::::::::::::::::::::
XP_005 LRYQDTFLPGNLPPLWFGYDIVKRLIMRLCSVCLQSILELEKERIQLLCNNLNQYSQHIS
220 230 240 250 260 270
160 170 180 190 200 210
pF1KE1 LFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDK
280 290 300 310 320 330
220 230 240 250 260 270
pF1KE1 ERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLK
340 350 360 370 380 390
280 290 300 310 320 330
pF1KE1 LDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIV
400 410 420 430 440 450
340 350 360 370 380 390
pF1KE1 SKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEEGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_005 SKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEGGW
460 470 480 490 500 510
400 410 420
pF1KE1 WFGSLNGKKGHFPAAYVEELPSNAGNTATKA
:::::::::::::::::::::::::::::::
XP_005 WFGSLNGKKGHFPAAYVEELPSNAGNTATKA
520 530 540
>>NP_001165102 (OMIM: 607496) nostrin isoform 4 [Homo sa (563 aa)
initn: 1932 init1: 1932 opt: 1932 Z-score: 1052.8 bits: 204.3 E(85289): 6.7e-52
Smith-Waterman score: 2460; 87.4% identity (87.4% similar) in 460 aa overlap (26-428:104-563)
10 20 30 40 50
pF1KE1 MKSTADLHQKLGKAIELEAIKPTYQVLNVQEKKRKSLDNEVEKTANLVISNWNQQ
::::::::::::::::::::::::::::::
NP_001 WASEGMKSTADLHQKLGKAIELEAIKPTYQVLNVQEKKRKSLDNEVEKTANLVISNWNQQ
80 90 100 110 120 130
60 70 80 90 100 110
pF1KE1 IKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRKLLNKLTKSTEKLEKEDENYYQKNMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRKLLNKLTKSTEKLEKEDENYYQKNMA
140 150 160 170 180 190
120 130
pF1KE1 GYSTRLKWENTLENCYQ-------------------------------------------
:::::::::::::::::
NP_001 GYSTRLKWENTLENCYQVTHSICLYAFWVKRAWGKCVSDLRYQDTFLPGNLPPLWFGYDI
200 210 220 230 240 250
140 150 160 170
pF1KE1 --------------SILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKID
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKRLIMRLCSVCLQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKID
260 270 280 290 300 310
180 190 200 210 220 230
pF1KE1 IEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKA
320 330 340 350 360 370
240 250 260 270 280 290
pF1KE1 SKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQR
380 390 400 410 420 430
300 310 320 330 340 350
pF1KE1 PQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAA
440 450 460 470 480 490
360 370 380 390 400 410
pF1KE1 QLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGHFPAAYVEELP
:::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
NP_001 QLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEGGWWFGSLNGKKGHFPAAYVEELP
500 510 520 530 540 550
420
pF1KE1 SNAGNTATKA
::::::::::
NP_001 SNAGNTATKA
560
>>XP_016858769 (OMIM: 607496) PREDICTED: nostrin isoform (324 aa)
initn: 1915 init1: 1915 opt: 1915 Z-score: 1046.5 bits: 202.3 E(85289): 1.5e-51
Smith-Waterman score: 1915; 99.3% identity (99.7% similar) in 297 aa overlap (132-428:28-324)
110 120 130 140 150 160
pF1KE1 LEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQ
.:::::::::::::::::::::::::::::
XP_016 MRRMTTHYIKWTPQDSRASFFPRTLLKKSILELEKERIQLLCNNLNQYSQHISLFGQ
10 20 30 40 50
170 180 190 200 210 220
pF1KE1 TLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRK
60 70 80 90 100 110
230 240 250 260 270 280
pF1KE1 SLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLL
120 130 140 150 160 170
290 300 310 320 330 340
pF1KE1 EANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKAS
180 190 200 210 220 230
350 360 370 380 390 400
pF1KE1 SGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEEGWWFGS
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_016 SGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEGGWWFGS
240 250 260 270 280 290
410 420
pF1KE1 LNGKKGHFPAAYVEELPSNAGNTATKA
:::::::::::::::::::::::::::
XP_016 LNGKKGHFPAAYVEELPSNAGNTATKA
300 310 320
>>XP_011508842 (OMIM: 607496) PREDICTED: nostrin isoform (521 aa)
initn: 1630 init1: 1630 opt: 1630 Z-score: 893.0 bits: 174.6 E(85289): 5.3e-43
Smith-Waterman score: 2158; 86.3% identity (86.3% similar) in 415 aa overlap (26-383:104-518)
10 20 30 40 50
pF1KE1 MKSTADLHQKLGKAIELEAIKPTYQVLNVQEKKRKSLDNEVEKTANLVISNWNQQ
::::::::::::::::::::::::::::::
XP_011 WASEGMKSTADLHQKLGKAIELEAIKPTYQVLNVQEKKRKSLDNEVEKTANLVISNWNQQ
80 90 100 110 120 130
60 70 80 90 100 110
pF1KE1 IKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRKLLNKLTKSTEKLEKEDENYYQKNMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRKLLNKLTKSTEKLEKEDENYYQKNMA
140 150 160 170 180 190
120 130
pF1KE1 GYSTRLKWENTLENCYQ-------------------------------------------
:::::::::::::::::
XP_011 GYSTRLKWENTLENCYQVTHSICLYAFWVKRAWGKCVSDLRYQDTFLPGNLPPLWFGYDI
200 210 220 230 240 250
140 150 160 170
pF1KE1 --------------SILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKID
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKRLIMRLCSVCLQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKID
260 270 280 290 300 310
180 190 200 210 220 230
pF1KE1 IEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKA
320 330 340 350 360 370
240 250 260 270 280 290
pF1KE1 SKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQR
380 390 400 410 420 430
300 310 320 330 340 350
pF1KE1 PQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAA
440 450 460 470 480 490
360 370 380 390 400 410
pF1KE1 QLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGHFPAAYVEELP
:::::::::::::::::::::::::
XP_011 QLSSRLCKALYSFQARQDDELNLEKESC
500 510 520
428 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:27:43 2016 done: Mon Nov 7 01:27:44 2016
Total Scan time: 9.990 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]