Result of FASTA (omim) for
pFN21AE1447
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1447, 292 aa
1>>>pF1KE1447 292 - 292 aa - 292 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0335+/-0.00036; mu= 16.8760+/- 0.022
mean_var=63.2514+/-12.583, 0's: 0 Z-trim(113.0): 18 B-trim: 44 in 1/48
Lambda= 0.161265
statistics sampled from 22088 (22094) to 22088 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.259), width: 16
Scan time: 6.970
The best scores are: opt bits E(85289)
NP_008826 (OMIM: 600807,605238,616739) histamine N ( 292) 1945 461.1 1.1e-129
XP_016859437 (OMIM: 600807,605238,616739) PREDICTE ( 258) 1630 387.8 1.2e-107
XP_011509366 (OMIM: 600807,605238,616739) PREDICTE ( 166) 1123 269.7 2.7e-72
XP_016859438 (OMIM: 600807,605238,616739) PREDICTE ( 161) 942 227.6 1.2e-59
NP_001019246 (OMIM: 600807,605238,616739) histamin ( 126) 419 105.8 4.3e-23
NP_001019245 (OMIM: 600807,605238,616739) histamin ( 51) 316 81.6 3.4e-16
>>NP_008826 (OMIM: 600807,605238,616739) histamine N-met (292 aa)
initn: 1945 init1: 1945 opt: 1945 Z-score: 2449.0 bits: 461.1 E(85289): 1.1e-129
Smith-Waterman score: 1945; 99.7% identity (100.0% similar) in 292 aa overlap (1-292:1-292)
10 20 30 40 50 60
pF1KE1 MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 GGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 SEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 KLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGDENGDLL
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
NP_008 KLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLL
190 200 210 220 230 240
250 260 270 280 290
pF1KE1 WDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 WDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA
250 260 270 280 290
>>XP_016859437 (OMIM: 600807,605238,616739) PREDICTED: h (258 aa)
initn: 1630 init1: 1630 opt: 1630 Z-score: 2053.7 bits: 387.8 E(85289): 1.2e-107
Smith-Waterman score: 1630; 97.2% identity (98.8% similar) in 253 aa overlap (40-292:6-258)
10 20 30 40 50 60
pF1KE1 SDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIGGGAGEIDLQ
: . . .:::::::::::::::::::::::
XP_016 MAETLLSAWMTEIGDTKSEIKILSIGGGAGEIDLQ
10 20 30
70 80 90 100 110 120
pF1KE1 ILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETSSEYQSRMLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETSSEYQSRMLE
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 KKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWDKLWKKYGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWDKLWKKYGSR
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 FPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGDENGDLLWDFLTETCN
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_016 FPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLLWDFLTETCN
160 170 180 190 200 210
250 260 270 280 290
pF1KE1 FNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA
:::::::::::::::::::::::::::::::::::::::::::
XP_016 FNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA
220 230 240 250
>>XP_011509366 (OMIM: 600807,605238,616739) PREDICTED: h (166 aa)
initn: 1123 init1: 1123 opt: 1123 Z-score: 1419.0 bits: 269.7 E(85289): 2.7e-72
Smith-Waterman score: 1123; 99.4% identity (100.0% similar) in 166 aa overlap (127-292:1-166)
100 110 120 130 140 150
pF1KE1 KYKELVAKTSNLENVKFAWHKETSSEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPATLK
::::::::::::::::::::::::::::::
XP_011 MLEKKELQKWDFIHMIQMLYYVKDIPATLK
10 20 30
160 170 180 190 200 210
pF1KE1 FFHSLLGTNAKMLIIVVSGSSGWDKLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFHSLLGTNAKMLIIVVSGSSGWDKLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYE
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE1 CYDLLSTMDISDCFIDGDENGDLLWDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKE
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
XP_011 CYDLLSTMDISDCFIDGNENGDLLWDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKE
100 110 120 130 140 150
280 290
pF1KE1 GKVLFNNTLSFIVIEA
::::::::::::::::
XP_011 GKVLFNNTLSFIVIEA
160
>>XP_016859438 (OMIM: 600807,605238,616739) PREDICTED: h (161 aa)
initn: 942 init1: 942 opt: 942 Z-score: 1191.6 bits: 227.6 E(85289): 1.2e-59
Smith-Waterman score: 942; 99.3% identity (100.0% similar) in 144 aa overlap (1-144:1-144)
10 20 30 40 50 60
pF1KE1 MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWD
:::::::::::::::::::::::.
XP_016 SEYQSRMLEKKELQKWDFIHMIQVNENLLISNFTSDHDLPK
130 140 150 160
>>NP_001019246 (OMIM: 600807,605238,616739) histamine N- (126 aa)
initn: 419 init1: 419 opt: 419 Z-score: 535.5 bits: 105.8 E(85289): 4.3e-23
Smith-Waterman score: 419; 100.0% identity (100.0% similar) in 63 aa overlap (1-63:1-63)
10 20 30 40 50 60
pF1KE1 MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETS
:::
NP_001 GGADCLIRGSSRVLKRNSCFILCSTRQKDKPGMRIHDERSSELPFGAARLESKSAFPSFL
70 80 90 100 110 120
>>NP_001019245 (OMIM: 600807,605238,616739) histamine N- (51 aa)
initn: 316 init1: 316 opt: 316 Z-score: 411.8 bits: 81.6 E(85289): 3.4e-16
Smith-Waterman score: 316; 100.0% identity (100.0% similar) in 46 aa overlap (1-46:1-46)
10 20 30 40 50 60
pF1KE1 MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRYQNCC
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 GGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETS
292 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:43:25 2016 done: Mon Nov 7 00:43:26 2016
Total Scan time: 6.970 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]