Result of FASTA (omim) for
pFN21AE1440
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1440, 349 aa
1>>>pF1KE1440 349 - 349 aa - 349 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6676+/-0.000366; mu= 20.6433+/- 0.023
mean_var=76.5651+/-15.483, 0's: 0 Z-trim(113.5): 69 B-trim: 59 in 1/53
Lambda= 0.146575
statistics sampled from 22831 (22902) to 22831 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.269), width: 16
Scan time: 7.300
The best scores are: opt bits E(85289)
NP_004616 (OMIM: 228930,276820,601570) protein Wnt ( 349) 2477 533.3 3.1e-151
XP_011532393 (OMIM: 228930,276820,601570) PREDICTE ( 282) 2031 438.9 6.5e-123
NP_478679 (OMIM: 601967) protein Wnt-7b precursor ( 349) 2026 437.9 1.6e-122
XP_011528668 (OMIM: 601967) PREDICTED: protein Wnt ( 353) 1967 425.4 9e-119
NP_078613 (OMIM: 601968) protein Wnt-2b isoform WN ( 391) 1210 265.4 1.5e-70
NP_004176 (OMIM: 601968) protein Wnt-2b isoform WN ( 372) 1209 265.2 1.7e-70
NP_110388 (OMIM: 158330,603490,611812) protein Wnt ( 351) 1173 257.5 3.1e-68
XP_011539899 (OMIM: 158330,603490,611812) PREDICTE ( 373) 1168 256.5 6.8e-68
NP_110402 (OMIM: 606361) protein Wnt-5b precursor ( 359) 1157 254.2 3.3e-67
NP_116031 (OMIM: 606361) protein Wnt-5b precursor ( 359) 1157 254.2 3.3e-67
XP_011532389 (OMIM: 164975,180700) PREDICTED: prot ( 365) 1140 250.6 4.1e-66
XP_011532388 (OMIM: 164975,180700) PREDICTED: prot ( 365) 1140 250.6 4.1e-66
XP_011532387 (OMIM: 164975,180700) PREDICTED: prot ( 365) 1140 250.6 4.1e-66
NP_001243034 (OMIM: 164975,180700) protein Wnt-5a ( 365) 1140 250.6 4.1e-66
XP_006713387 (OMIM: 164975,180700) PREDICTED: prot ( 365) 1140 250.6 4.1e-66
XP_016862617 (OMIM: 164975,180700) PREDICTED: prot ( 365) 1140 250.6 4.1e-66
XP_011532391 (OMIM: 164975,180700) PREDICTED: prot ( 365) 1140 250.6 4.1e-66
XP_011532390 (OMIM: 164975,180700) PREDICTED: prot ( 365) 1140 250.6 4.1e-66
NP_003383 (OMIM: 164975,180700) protein Wnt-5a iso ( 380) 1140 250.6 4.2e-66
XP_016862616 (OMIM: 164975,180700) PREDICTED: prot ( 394) 1140 250.6 4.3e-66
NP_110380 (OMIM: 165330,273395) proto-oncogene Wnt ( 355) 1122 246.7 5.6e-65
XP_011539900 (OMIM: 158330,603490,611812) PREDICTE ( 296) 1115 245.2 1.4e-64
NP_003382 (OMIM: 147870) protein Wnt-2 precursor [ ( 360) 1105 243.2 6.8e-64
NP_149122 (OMIM: 606359) protein Wnt-3a precursor ( 352) 1102 242.5 1e-63
XP_011542621 (OMIM: 606359) PREDICTED: protein Wnt ( 446) 1102 242.6 1.2e-63
NP_001278809 (OMIM: 601968) protein Wnt-2b isoform ( 299) 1083 238.4 1.5e-62
NP_476509 (OMIM: 606267) protein Wnt-16 isoform 1 ( 365) 1083 238.5 1.7e-62
NP_057171 (OMIM: 606267) protein Wnt-16 isoform 2 ( 355) 1082 238.3 2e-62
NP_005421 (OMIM: 164820,615220,615221) proto-oncog ( 370) 981 217.0 5.4e-56
NP_003384 (OMIM: 601396) protein Wnt-8b precursor ( 351) 891 197.9 2.8e-50
NP_004617 (OMIM: 603699) protein Wnt-11 precursor ( 354) 882 196.0 1.1e-49
XP_005274288 (OMIM: 603699) PREDICTED: protein Wnt ( 354) 882 196.0 1.1e-49
XP_011543542 (OMIM: 603699) PREDICTED: protein Wnt ( 364) 853 189.9 7.5e-48
XP_011543540 (OMIM: 603699) PREDICTED: protein Wnt ( 364) 853 189.9 7.5e-48
XP_011543541 (OMIM: 603699) PREDICTED: protein Wnt ( 364) 853 189.9 7.5e-48
NP_003387 (OMIM: 602864) protein Wnt-9b isoform 1 ( 357) 822 183.3 7e-46
XP_011523480 (OMIM: 602864) PREDICTED: protein Wnt ( 363) 822 183.3 7.1e-46
NP_490645 (OMIM: 606360) protein Wnt-8a isoform 3 ( 351) 821 183.1 8e-46
NP_001287868 (OMIM: 606360) protein Wnt-8a isoform ( 369) 821 183.1 8.3e-46
XP_016865314 (OMIM: 606360) PREDICTED: protein Wnt ( 391) 821 183.1 8.6e-46
NP_001287867 (OMIM: 606360) protein Wnt-8a isoform ( 386) 810 180.8 4.3e-45
XP_016865313 (OMIM: 606360) PREDICTED: protein Wnt ( 408) 810 180.8 4.4e-45
NP_003386 (OMIM: 602863) protein Wnt-9a precursor ( 365) 794 177.4 4.3e-44
XP_011542573 (OMIM: 602863) PREDICTED: protein Wnt ( 295) 771 172.4 1.1e-42
XP_016873730 (OMIM: 603699) PREDICTED: protein Wnt ( 251) 767 171.5 1.7e-42
XP_011543543 (OMIM: 603699) PREDICTED: protein Wnt ( 251) 767 171.5 1.7e-42
XP_016875408 (OMIM: 225300,601906,617073) PREDICTE ( 267) 713 160.1 5e-39
XP_011537024 (OMIM: 225300,601906,617073) PREDICTE ( 267) 713 160.1 5e-39
NP_003385 (OMIM: 225300,601906,617073) protein Wnt ( 389) 713 160.3 6.4e-39
XP_011541927 (OMIM: 606360) PREDICTED: protein Wnt ( 337) 697 156.9 6.1e-38
>>NP_004616 (OMIM: 228930,276820,601570) protein Wnt-7a (349 aa)
initn: 2477 init1: 2477 opt: 2477 Z-score: 2836.2 bits: 533.3 E(85289): 3.1e-151
Smith-Waterman score: 2477; 100.0% identity (100.0% similar) in 349 aa overlap (1-349:1-349)
10 20 30 40 50 60
pF1KE1 MNRKARRCLGHLFLSLGMVYLRIGGFSSVVALGASIICNKIPGLAPRQRAICQSRPDAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MNRKARRCLGHLFLSLGMVYLRIGGFSSVVALGASIICNKIPGLAPRQRAICQSRPDAII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAIT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIRYGIGFAKVFVDAREIKQNARTLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIRYGIGFAKVFVDAREIKQNARTLM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 NLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNKTAPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNKTAPQ
250 260 270 280 290 300
310 320 330 340
pF1KE1 ASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK
310 320 330 340
>>XP_011532393 (OMIM: 228930,276820,601570) PREDICTED: p (282 aa)
initn: 2031 init1: 2031 opt: 2031 Z-score: 2327.7 bits: 438.9 E(85289): 6.5e-123
Smith-Waterman score: 2031; 100.0% identity (100.0% similar) in 282 aa overlap (68-349:1-282)
40 50 60 70 80 90
pF1KE1 CNKIPGLAPRQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKEL
::::::::::::::::::::::::::::::
XP_011 MGLDECQFQFRNGRWNCSALGERTVFGKEL
10 20 30
100 110 120 130 140 150
pF1KE1 KVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE1 YGIGFAKVFVDAREIKQNARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGIGFAKVFVDAREIKQNARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTT
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE1 LPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNY
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE1 CEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCN
220 230 240 250 260 270
340
pF1KE1 TCSERTEMYTCK
::::::::::::
XP_011 TCSERTEMYTCK
280
>>NP_478679 (OMIM: 601967) protein Wnt-7b precursor [Hom (349 aa)
initn: 2011 init1: 2011 opt: 2026 Z-score: 2320.8 bits: 437.9 E(85289): 1.6e-122
Smith-Waterman score: 2026; 77.9% identity (94.0% similar) in 349 aa overlap (1-349:1-349)
10 20 30 40 50 60
pF1KE1 MNRKARRCLGHLFLSLGMVYLRIGGFSSVVALGASIICNKIPGLAPRQRAICQSRPDAII
:.:. :. . ..:: .:..:...:..::::::::.:::::::::::::::::::::::::
NP_478 MHRNFRKWIFYVFLCFGVLYVKLGALSSVVALGANIICNKIPGLAPRQRAICQSRPDAII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAIT
:::::.:::..:::.::: ::::::::::.::::.::.:::::::::::: :::::::.:
NP_478 VIGEGAQMGINECQYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIRYGIGFAKVFVDAREIKQNARTLM
:::.:::::.::::.:::: :.. :::::::::::.:::: :.. ::::::::.::: ::
NP_478 AACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREIKKNARRLM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 NLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEP
::::::::::.::. :.::::::::::::::::::::::.:::.:..::.::: ::.::
NP_478 NLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQVEV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNKTAPQ
::::: ..::::.::. ::.:::.:::::::::::::::: .::::::::: ::.:.:
NP_478 VRASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNRTSPG
250 260 270 280 290 300
310 320 330 340
pF1KE1 ASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK
:.::: ::::::::::::..::::::::::::.:::::::::::..:::
NP_478 ADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
310 320 330 340
>>XP_011528668 (OMIM: 601967) PREDICTED: protein Wnt-7b (353 aa)
initn: 1963 init1: 1963 opt: 1967 Z-score: 2253.3 bits: 425.4 E(85289): 9e-119
Smith-Waterman score: 1967; 79.9% identity (93.2% similar) in 338 aa overlap (12-349:20-353)
10 20 30 40 50
pF1KE1 MNRKARRCLGHLFLSLGMVYLRIGGFSSVVALGASIICNKIPGLAPRQRAIC
:.:: : :: ..::::::::.:::::::::::::::::
XP_011 MLLLSPRSALVSVYCPQIFLLLSSGS-YL---ALSSVVALGANIICNKIPGLAPRQRAIC
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 QSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIA
:::::::::::::.:::..:::.::: ::::::::::.::::.::.:::::::::::: :
XP_011 QSRPDAIIVIGEGAQMGINECQYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 AGVAHAITAACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIRYGIGFAKVFVDAREI
::::::.::::.:::::.::::.:::: :.. :::::::::::.:::: :.. :::::::
XP_011 AGVAHAVTAACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 KQNARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKY
:.::: ::::::::::::.::. :.::::::::::::::::::::::.:::.:..::.::
XP_011 KKNARRLMNLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 NEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGR
: ::.:: ::::: ..::::.::. ::.:::.:::::::::::::::: .:::::::::
XP_011 NAAVQVEVVRASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGR
240 250 260 270 280 290
300 310 320 330 340
pF1KE1 ACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK
::.:.: :.::: ::::::::::::..::::::::::::.:::::::::::..:::
XP_011 LCNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
300 310 320 330 340 350
>>NP_078613 (OMIM: 601968) protein Wnt-2b isoform WNT-2B (391 aa)
initn: 1207 init1: 409 opt: 1210 Z-score: 1387.7 bits: 265.4 E(85289): 1.5e-70
Smith-Waterman score: 1210; 49.7% identity (75.7% similar) in 346 aa overlap (8-349:43-380)
10 20 30
pF1KE1 MNRKARRCLGHLFLSLGMVYLRIG-GFSSVVALGASI
:: :.: : . :. .. . :::: .
NP_078 LPLRRASAPVPVPSPAAPDGSRASARLGLACL--LLLLLLTLPARVDTSWWYIGALGARV
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE1 ICNKIPGLAPRQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALG-ERTVFGK
::..::::. ::: .:: :: . .:::.. . ::: :::. ::::..: ..::::.
NP_078 ICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDRDHTVFGR
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE1 ELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQGQYHRDEG-WKWGGCSA
. .::::::.::: .:::.:::: ::.::.:: :.:: .:..: ..: . :::::
NP_078 VMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRHHDQRGDFDWGGCSD
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE1 DIRYGIGFAKVFVDAREIK-QNARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKT
.:.::. :::.::::.: . ..::.:::::::. :: ... .:::::::::::::: .:
NP_078 NIHYGVRFAKAFVDAKEKRLKDARALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRT
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE1 CWTTLPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEK
:: .: .::. : :. .:. ::.: .. . : : .. .::. :::::...
NP_078 CWRALSDFRRTGDYLRRRYDGAVQVMATQDGAN----FTAARQ--GYRRATRTDLVYFDN
260 270 280 290 300
280 290 300 310 320 330
pF1KE1 SPNYCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCY
::.:: : ..::.:: ::.:.::. ..::..:::::::.: . .:: ::.:::::::
NP_078 SPDYCVLDKAAGSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECKFHWCCA
310 320 330 340 350 360
340
pF1KE1 VKCNTCSERTEMYTCK
:.:. : . ....:::
NP_078 VRCKECRNTVDVHTCKAPKKAEWLDQT
370 380 390
>>NP_004176 (OMIM: 601968) protein Wnt-2b isoform WNT-2B (372 aa)
initn: 1207 init1: 409 opt: 1209 Z-score: 1386.8 bits: 265.2 E(85289): 1.7e-70
Smith-Waterman score: 1209; 51.6% identity (77.6% similar) in 322 aa overlap (31-349:46-361)
10 20 30 40 50 60
pF1KE1 MNRKARRCLGHLFLSLGMVYLRIGGFSSVVALGASIICNKIPGLAPRQRAICQSRPDAII
:::: .::..::::. ::: .:: :: .
NP_004 QLKTEGSLRTAVPGIPTQSAFNKCLQRYIGALGARVICDNIPGLVSRQRQLCQRYPDIMR
20 30 40 50 60 70
70 80 90 100 110
pF1KE1 VIGEGSQMGLDECQFQFRNGRWNCSALG-ERTVFGKELKVGSREAAFTYAIIAAGVAHAI
.:::.. . ::: :::. ::::..: ..::::. . .::::::.::: .:::.:::
NP_004 SVGEGAREWIRECQHQFRHHRWNCTTLDRDHTVFGRVMLRSSREAAFVYAISSAGVVHAI
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE1 TAACTQGNLSDCGCDKEKQGQYHRDEG-WKWGGCSADIRYGIGFAKVFVDAREIK-QNAR
: ::.::.:: :.:: .:..: ..: . ::::: .:.::. :::.::::.: . ..::
NP_004 TRACSQGELSVCSCDPYTRGRHHDQRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRLKDAR
140 150 160 170 180 190
180 190 200 210 220 230
pF1KE1 TLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVH
.:::::::. :: ... .:::::::::::::: .::: .: .::. : :. .:. ::.
NP_004 ALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQ
200 210 220 230 240 250
240 250 260 270 280 290
pF1KE1 VEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNKT
: .. . : : .. .::. :::::...::.:: : ..::.:: ::.:.::
NP_004 VMATQDGAN----FTAARQ--GYRRATRTDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKT
260 270 280 290 300
300 310 320 330 340
pF1KE1 APQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK
. ..::..:::::::.: . .:: ::.::::::: :.:. : . ....:::
NP_004 SKGTDGCEIMCCGRGYDTTRVTRVTQCECKFHWCCAVRCKECRNTVDVHTCKAPKKAEWL
310 320 330 340 350 360
NP_004 DQT
370
>>NP_110388 (OMIM: 158330,603490,611812) protein Wnt-4 p (351 aa)
initn: 1133 init1: 392 opt: 1173 Z-score: 1345.9 bits: 257.5 E(85289): 3.1e-68
Smith-Waterman score: 1173; 45.5% identity (72.9% similar) in 354 aa overlap (6-349:4-351)
10 20 30 40 50
pF1KE1 MNRKARRCLGHLFLSLGMVY-------LRIGGFSSVVALGASIICNKIPGLAPRQRAICQ
: :: : : . :. : .. .::: ... :.:. :: :: .:.
NP_110 MSPRSCLRSLRLLVFAVFSAAASNWLYLAKLSSVGSISEEETCEKLKGLIQRQVQMCK
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 SRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAA
... . .:.:....:::.:::: :::::.: :::: . :.:::::.::: .:
NP_110 RNLEVMDSVRRGAQLAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQGTREAAFVYAISSA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 GVAHAITAACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIRYGIGFAKVFVDAREIK
::: :.: ::..:.: ::::. .: .:..:.::: .: ::..:.. :::.:: .
NP_110 GVAFAVTRACSSGELEKCGCDRTVHGV--SPQGFQWSGCSDNIAYGVAFSQSFVDVRERS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 QNA---RTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKD
..: :.:::::::::::: . .:..::::::::::: .:::: ..: ::..:..::.
NP_110 KGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 KYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQ
:.. :..::: :.. .. . . ... : ::::.: ::..::.: .: .::.
NP_110 KFDGATEVEPRRVGSSRA----LVPRNAQFKPHTDEDLVYLEPSPDFCEQDMRSGVLGTR
240 250 260 270 280 290
300 310 320 330 340
pF1KE1 GRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK
::.::::. .::.:.:::::..: : . .:.:::::::.::: :.. .:..::.
NP_110 GRTCNKTSKAIDGCELLCCGRGFHTAQVELAERCSCKFHWCCFVKCRQCQRLVELHTCR
300 310 320 330 340 350
>>XP_011539899 (OMIM: 158330,603490,611812) PREDICTED: p (373 aa)
initn: 1133 init1: 392 opt: 1168 Z-score: 1339.9 bits: 256.5 E(85289): 6.8e-68
Smith-Waterman score: 1168; 46.1% identity (74.7% similar) in 336 aa overlap (17-349:44-373)
10 20 30 40
pF1KE1 MNRKARRCLGHLFLSLGMVYLRIGGFSSVVALGASIICNKIPGLAP
: . .. .::: ... :.:. ::
XP_011 QGSLCSTQGKRNKRLPRTLPNQRGYEGEDTGHIPRYLAKLSSVGSISEEETCEKLKGLIQ
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE1 RQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAF
:: .:. ... . .:.:....:::.:::: :::::.: :::: . :.:::::
XP_011 RQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQGTREAAF
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE1 TYAIIAAGVAHAITAACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIRYGIGFAKVF
.::: .:::: :.: ::..:.: ::::. .: .:..:.::: .: ::..:.. :
XP_011 VYAISSAGVAFAVTRACSSGELEKCGCDRTVHGV--SPQGFQWSGCSDNIAYGVAFSQSF
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE1 VDAREIKQNA---RTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRE
::.:: ...: :.:::::::::::: . .:..::::::::::: .:::: ..: ::.
XP_011 VDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQ
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE1 LGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPV
.:..::.:.. :..::: :.. .. . . ... : ::::.: ::..::.:
XP_011 VGHALKEKFDGATEVEPRRVGSSRA----LVPRNAQFKPHTDEDLVYLEPSPDFCEQDMR
260 270 280 290 300
290 300 310 320 330 340
pF1KE1 TGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERT
.: .::.::.::::. .::.:.:::::..: : . .:.:::::::.::: :.. .
XP_011 SGVLGTRGRTCNKTSKAIDGCELLCCGRGFHTAQVELAERCSCKFHWCCFVKCRQCQRLV
310 320 330 340 350 360
pF1KE1 EMYTCK
:..::.
XP_011 ELHTCR
370
>>NP_110402 (OMIM: 606361) protein Wnt-5b precursor [Hom (359 aa)
initn: 693 init1: 693 opt: 1157 Z-score: 1327.5 bits: 254.2 E(85289): 3.3e-67
Smith-Waterman score: 1157; 47.7% identity (73.4% similar) in 327 aa overlap (32-349:42-359)
10 20 30 40 50 60
pF1KE1 NRKARRCLGHLFLSLGMVYLRIGGFSSVVALGASIICNKIPGLAPRQRAICQSRPDAIIV
.::. .:...:::.: :: .:: . .
NP_110 LLSSWAQLLTDANSWWSLALNPVQRPEMFIIGAQPVCSQLPGLSPGQRKLCQLYQEHMAY
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE1 IGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAITA
::::.. :. ::: :::. :::::. . .:::. ...::::.:::.:. ::::..::.
NP_110 IGEGAKTGIKECQHQFRQRRWNCSTADNASVFGRVMQIGSRETAFTHAVSAAGVVNAISR
80 90 100 110 120 130
130 140 150 160 170
pF1KE1 ACTQGNLSDCGCDKEKQGQ-YHRDEGWKWGGCSADIRYGIGFAKVFVDAREIKQN-----
:: .:.:: :::.. . . :: : ::::. ...:: ::: :::::: ..:
NP_110 ACREGELSTCGCSRTARPKDLPRD--WLWGGCGDNVEYGYRFAKEFVDAREREKNFAKGS
140 150 160 170 180
180 190 200 210 220 230
pF1KE1 ---ARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKY
.:.::::.::::::. . . . ::::::::::. :::: : .::..: ::.::
NP_110 EEQGRVLMNLQNNEAGRRAVYKMADVACKCHGVSGSCSLKTCWLQLAEFRKVGDRLKEKY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 NEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGR
. :. .:..:. : ... . . .: ::::.. ::.:: .. :::.:::::
NP_110 DSAA---AMRVTRKGRLELVNSR----FTQPTPEDLVYVDPSPDYCLRNESTGSLGTQGR
250 260 270 280 290 300
300 310 320 330 340
pF1KE1 ACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK
::::. .::.::::::::: . ..: .:.:::::::.:.:. :.: ...: ::
NP_110 LCNKTSEGMDGCELMCCGRGYNQFKSVQVERCHCKFHWCCFVRCKKCTEIVDQYICK
310 320 330 340 350
>>NP_116031 (OMIM: 606361) protein Wnt-5b precursor [Hom (359 aa)
initn: 693 init1: 693 opt: 1157 Z-score: 1327.5 bits: 254.2 E(85289): 3.3e-67
Smith-Waterman score: 1157; 47.7% identity (73.4% similar) in 327 aa overlap (32-349:42-359)
10 20 30 40 50 60
pF1KE1 NRKARRCLGHLFLSLGMVYLRIGGFSSVVALGASIICNKIPGLAPRQRAICQSRPDAIIV
.::. .:...:::.: :: .:: . .
NP_116 LLSSWAQLLTDANSWWSLALNPVQRPEMFIIGAQPVCSQLPGLSPGQRKLCQLYQEHMAY
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE1 IGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAITA
::::.. :. ::: :::. :::::. . .:::. ...::::.:::.:. ::::..::.
NP_116 IGEGAKTGIKECQHQFRQRRWNCSTADNASVFGRVMQIGSRETAFTHAVSAAGVVNAISR
80 90 100 110 120 130
130 140 150 160 170
pF1KE1 ACTQGNLSDCGCDKEKQGQ-YHRDEGWKWGGCSADIRYGIGFAKVFVDAREIKQN-----
:: .:.:: :::.. . . :: : ::::. ...:: ::: :::::: ..:
NP_116 ACREGELSTCGCSRTARPKDLPRD--WLWGGCGDNVEYGYRFAKEFVDAREREKNFAKGS
140 150 160 170 180
180 190 200 210 220 230
pF1KE1 ---ARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKY
.:.::::.::::::. . . . ::::::::::. :::: : .::..: ::.::
NP_116 EEQGRVLMNLQNNEAGRRAVYKMADVACKCHGVSGSCSLKTCWLQLAEFRKVGDRLKEKY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 NEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGR
. :. .:..:. : ... . . .: ::::.. ::.:: .. :::.:::::
NP_116 DSAA---AMRVTRKGRLELVNSR----FTQPTPEDLVYVDPSPDYCLRNESTGSLGTQGR
250 260 270 280 290 300
300 310 320 330 340
pF1KE1 ACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK
::::. .::.::::::::: . ..: .:.:::::::.:.:. :.: ...: ::
NP_116 LCNKTSEGMDGCELMCCGRGYNQFKSVQVERCHCKFHWCCFVRCKKCTEIVDQYICK
310 320 330 340 350
349 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:09:51 2016 done: Sun Nov 6 23:09:52 2016
Total Scan time: 7.300 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]