Result of FASTA (omim) for
pFN21AE1427
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1427, 1315 aa
1>>>pF1KE1427 1315 - 1315 aa - 1315 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.4734+/-0.000603; mu= 8.9871+/- 0.037
mean_var=466.5952+/-111.011, 0's: 0 Z-trim(116.2): 2267 B-trim: 1051 in 1/51
Lambda= 0.059375
statistics sampled from 24324 (27145) to 24324 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.318), width: 16
Scan time: 17.990
The best scores are: opt bits E(85289)
NP_056505 (OMIM: 607652) serine/threonine-protein (1315) 8687 761.4 9.5e-219
XP_005246521 (OMIM: 607652) PREDICTED: serine/thre (1315) 8687 761.4 9.5e-219
XP_011509262 (OMIM: 607652) PREDICTED: serine/thre (1261) 8342 731.8 7.3e-210
NP_001230242 (OMIM: 607652) serine/threonine-prote (1294) 5560 493.5 4.1e-138
XP_016859293 (OMIM: 607652) PREDICTED: serine/thre (1294) 5560 493.5 4.1e-138
XP_011509261 (OMIM: 607652) PREDICTED: serine/thre (1306) 5180 460.9 2.6e-128
XP_011509263 (OMIM: 607652) PREDICTED: serine/thre ( 784) 5157 458.6 7.8e-128
XP_016859294 (OMIM: 607652) PREDICTED: serine/thre ( 784) 5157 458.6 7.8e-128
NP_001271293 (OMIM: 613472) serine/threonine-prote ( 470) 587 66.8 4.2e-10
NP_001092906 (OMIM: 613472) serine/threonine-prote ( 472) 587 66.8 4.2e-10
NP_003151 (OMIM: 243060,603495) aurora kinase C is ( 275) 582 66.0 4.3e-10
NP_001015879 (OMIM: 243060,603495) aurora kinase C ( 290) 582 66.0 4.4e-10
NP_001015878 (OMIM: 243060,603495) aurora kinase C ( 309) 582 66.0 4.6e-10
NP_689933 (OMIM: 604044) serine/threonine-protein ( 506) 572 65.5 1.1e-09
NP_002489 (OMIM: 604044) serine/threonine-protein ( 506) 572 65.5 1.1e-09
XP_016855474 (OMIM: 611223,615937) PREDICTED: RAC- ( 418) 561 64.5 1.9e-09
XP_011542314 (OMIM: 611223,615937) PREDICTED: RAC- ( 435) 561 64.5 1.9e-09
NP_859029 (OMIM: 611223,615937) RAC-gamma serine/t ( 465) 561 64.5 2e-09
NP_001193658 (OMIM: 611223,615937) RAC-gamma serin ( 465) 561 64.5 2e-09
XP_016876564 (OMIM: 114480,114500,164730,167000,17 ( 530) 562 64.7 2e-09
XP_016876567 (OMIM: 114480,114500,164730,167000,17 ( 530) 562 64.7 2e-09
XP_016876566 (OMIM: 114480,114500,164730,167000,17 ( 530) 562 64.7 2e-09
XP_016876565 (OMIM: 114480,114500,164730,167000,17 ( 530) 562 64.7 2e-09
XP_005273051 (OMIM: 611223,615937) PREDICTED: RAC- ( 479) 561 64.6 2e-09
XP_005273052 (OMIM: 611223,615937) PREDICTED: RAC- ( 479) 561 64.6 2e-09
NP_005456 (OMIM: 611223,615937) RAC-gamma serine/t ( 479) 561 64.6 2e-09
NP_001139571 (OMIM: 604044) serine/threonine-prote ( 489) 560 64.5 2.1e-09
XP_011530307 (OMIM: 263520,604588) PREDICTED: seri ( 715) 558 64.6 2.9e-09
NP_005154 (OMIM: 114480,114500,164730,167000,17692 ( 480) 554 64.0 3e-09
XP_005267458 (OMIM: 114480,114500,164730,167000,17 ( 480) 554 64.0 3e-09
NP_001014431 (OMIM: 114480,114500,164730,167000,17 ( 480) 554 64.0 3e-09
NP_001014432 (OMIM: 114480,114500,164730,167000,17 ( 480) 554 64.0 3e-09
NP_005618 (OMIM: 602958) serine/threonine-protein ( 431) 553 63.8 3e-09
NP_001137150 (OMIM: 602958) serine/threonine-prote ( 445) 553 63.8 3.1e-09
NP_001137149 (OMIM: 602958) serine/threonine-prote ( 459) 553 63.8 3.1e-09
NP_001186193 (OMIM: 607589) serine/threonine-prote ( 367) 550 63.4 3.3e-09
NP_733794 (OMIM: 607589) serine/threonine-protein ( 367) 550 63.4 3.3e-09
NP_001137148 (OMIM: 602958) serine/threonine-prote ( 526) 553 63.9 3.3e-09
XP_011534373 (OMIM: 602958) PREDICTED: serine/thre ( 526) 553 63.9 3.3e-09
NP_037389 (OMIM: 607591) serine/threonine-protein ( 496) 552 63.8 3.4e-09
NP_001028750 (OMIM: 607591) serine/threonine-prote ( 496) 552 63.8 3.4e-09
NP_057360 (OMIM: 607589) serine/threonine-protein ( 427) 550 63.5 3.6e-09
NP_001186328 (OMIM: 263520,604588) serine/threonin (1189) 558 64.9 3.7e-09
NP_001186329 (OMIM: 263520,604588) serine/threonin (1214) 558 65.0 3.8e-09
XP_011530306 (OMIM: 263520,604588) PREDICTED: seri (1214) 558 65.0 3.8e-09
XP_006714291 (OMIM: 263520,604588) PREDICTED: seri (1227) 558 65.0 3.8e-09
NP_001186327 (OMIM: 263520,604588) serine/threonin (1242) 558 65.0 3.8e-09
XP_011530305 (OMIM: 263520,604588) PREDICTED: seri (1258) 558 65.0 3.9e-09
NP_036356 (OMIM: 263520,604588) serine/threonine-p (1258) 558 65.0 3.9e-09
NP_001186326 (OMIM: 263520,604588) serine/threonin (1286) 558 65.0 3.9e-09
>>NP_056505 (OMIM: 607652) serine/threonine-protein kina (1315 aa)
initn: 8687 init1: 8687 opt: 8687 Z-score: 4048.2 bits: 761.4 E(85289): 9.5e-219
Smith-Waterman score: 8687; 99.8% identity (100.0% similar) in 1315 aa overlap (1-1315:1-1315)
10 20 30 40 50 60
pF1KE1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKDFLQGLLTKDPR
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
NP_056 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPEVLGQRSTDVVDLENEEPDSDNEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPEVLGQRSTDVVDLENEEPDSDNEW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 QHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILNGILEGASHILPAFRVLS
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_056 QHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILKGILEGASHILPAFRVLS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 SLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 CTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 SRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 ALAAICTAPVGLPDCWDAKEQVCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ALAAICTAPVGLPDCWDAKEQVCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 CCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEESTEVTLYFLTLLVFRLQNLPCGM
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
NP_056 CCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEESTEVTLYFLSLLVFRLQNLPCGM
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 EKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE1 TPPGSCGFYDGLLILLLQLLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TPPGSCGFYDGLLILLLQLLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE1 ELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLC
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE1 PSFLNQLRQAPHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PSFLNQLRQAPHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE1 CCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE1 LLSLLAHTARVLSPSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LLSLLAHTARVLSPSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE1 MALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE1 LGDPQAGIRRNVASALGNLGPEGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LGDPQAGIRRNVASALGNLGPEGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310
pF1KE1 QQEPGIHQVLVSLGASEKLSLLSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QQEPGIHQVLVSLGASEKLSLLSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
1270 1280 1290 1300 1310
>>XP_005246521 (OMIM: 607652) PREDICTED: serine/threonin (1315 aa)
initn: 8687 init1: 8687 opt: 8687 Z-score: 4048.2 bits: 761.4 E(85289): 9.5e-219
Smith-Waterman score: 8687; 99.8% identity (100.0% similar) in 1315 aa overlap (1-1315:1-1315)
10 20 30 40 50 60
pF1KE1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKDFLQGLLTKDPR
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_005 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPEVLGQRSTDVVDLENEEPDSDNEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPEVLGQRSTDVVDLENEEPDSDNEW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 QHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILNGILEGASHILPAFRVLS
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
XP_005 QHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILKGILEGASHILPAFRVLS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 SLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 CTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 SRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 ALAAICTAPVGLPDCWDAKEQVCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALAAICTAPVGLPDCWDAKEQVCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 CCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEESTEVTLYFLTLLVFRLQNLPCGM
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
XP_005 CCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEESTEVTLYFLSLLVFRLQNLPCGM
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 EKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE1 TPPGSCGFYDGLLILLLQLLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPPGSCGFYDGLLILLLQLLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE1 ELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLC
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE1 PSFLNQLRQAPHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSFLNQLRQAPHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE1 CCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE1 LLSLLAHTARVLSPSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLSLLAHTARVLSPSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE1 MALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE1 LGDPQAGIRRNVASALGNLGPEGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGDPQAGIRRNVASALGNLGPEGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310
pF1KE1 QQEPGIHQVLVSLGASEKLSLLSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQEPGIHQVLVSLGASEKLSLLSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
1270 1280 1290 1300 1310
>>XP_011509262 (OMIM: 607652) PREDICTED: serine/threonin (1261 aa)
initn: 8342 init1: 8342 opt: 8342 Z-score: 3888.7 bits: 731.8 E(85289): 7.3e-210
Smith-Waterman score: 8342; 99.8% identity (100.0% similar) in 1261 aa overlap (55-1315:1-1261)
30 40 50 60 70 80
pF1KE1 YSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAE
::::::::::::::::::::::::::::::
XP_011 MRGLRHPNIVHMLDSFETDKEVVVVTDYAE
10 20 30
90 100 110 120 130 140
pF1KE1 GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDF
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 GFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYATS
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE1 IFQLVSLILKDPVRWPSTISPCFKDFLQGLLTKDPRQRLSWPDLLYHPFIAGHVTIITEP
::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
XP_011 IFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPRQRLSWPDLLYHPFIAGHVTIITEP
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE1 AGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSRILTQAYKRMAEEAMQKKHQNTGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSRILTQAYKRMAEEAMQKKHQNTGPA
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE1 LEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILASELKSSWAKSGTGEVPSAPRENRTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILASELKSSWAKSGTGEVPSAPRENRTT
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE1 PDCERAFPEERPEVLGQRSTDVVDLENEEPDSDNEWQHLLETTEPVPIQLKAPLTLLCNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDCERAFPEERPEVLGQRSTDVVDLENEEPDSDNEWQHLLETTEPVPIQLKAPLTLLCNP
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE1 DFCQRIQSQLHEAGGQILNGILEGASHILPAFRVLSSLLSSCSDSVALYSFCREAGLPGL
::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
XP_011 DFCQRIQSQLHEAGGQILKGILEGASHILPAFRVLSSLLSSCSDSVALYSFCREAGLPGL
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE1 LLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFACTFNLERSQTSDSLQVFQEAANLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFACTFNLERSQTSDSLQVFQEAANLF
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE1 LDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGNSRAISKAFYSSLLTTQQVVLDGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGNSRAISKAFYSSLLTTQQVVLDGLL
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE1 HGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISSALAAICTAPVGLPDCWDAKEQVCW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISSALAAICTAPVGLPDCWDAKEQVCW
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE1 HLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYSCCLVSEGLCRLLGQEPLALESLFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYSCCLVSEGLCRLLGQEPLALESLFM
640 650 660 670 680 690
750 760 770 780 790 800
pF1KE1 LIQGKVKVVDWEESTEVTLYFLTLLVFRLQNLPCGMEKLGSDVATLFTHSHVVSLVSAAA
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_011 LIQGKVKVVDWEESTEVTLYFLSLLVFRLQNLPCGMEKLGSDVATLFTHSHVVSLVSAAA
700 710 720 730 740 750
810 820 830 840 850 860
pF1KE1 CLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRLTPPGSCGFYDGLLILLLQLLTEQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRLTPPGSCGFYDGLLILLLQLLTEQG
760 770 780 790 800 810
870 880 890 900 910 920
pF1KE1 KASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEGELSLSSPPSPEPDWTLISPQGMAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEGELSLSSPPSPEPDWTLISPQGMAA
820 830 840 850 860 870
930 940 950 960 970 980
pF1KE1 LLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLCPSFLNQLRQAPHGSEFLPVVVLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLCPSFLNQLRQAPHGSEFLPVVVLSV
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE1 CQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQVCCYHLPLMQVELPISLLTRLALMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQVCCYHLPLMQVELPISLLTRLALMD
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KE1 PTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSDLLSLLAHTARVLSPSHLSFIQELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSDLLSLLAHTARVLSPSHLSFIQELL
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150 1160
pF1KE1 AGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHSMALRGALQSQSGLLSLLLLGLGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHSMALRGALQSQSGLLSLLLLGLGDK
1060 1070 1080 1090 1100 1110
1170 1180 1190 1200 1210 1220
pF1KE1 DPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDPQAGIRRNVASALGNLGPEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDPQAGIRRNVASALGNLGPEGL
1120 1130 1140 1150 1160 1170
1230 1240 1250 1260 1270 1280
pF1KE1 GEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSLQQEPGIHQVLVSLGASEKLSLLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSLQQEPGIHQVLVSLGASEKLSLLSL
1180 1190 1200 1210 1220 1230
1290 1300 1310
pF1KE1 GNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
:::::::::::::::::::::::::::::::
XP_011 GNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
1240 1250 1260
>>NP_001230242 (OMIM: 607652) serine/threonine-protein k (1294 aa)
initn: 5591 init1: 5556 opt: 5560 Z-score: 2600.6 bits: 493.5 E(85289): 4.1e-138
Smith-Waterman score: 8490; 98.2% identity (98.4% similar) in 1315 aa overlap (1-1315:1-1294)
10 20 30 40 50 60
pF1KE1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKDFLQGLLTKDPR
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
NP_001 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPEVLGQRSTDVVDLENEEPDSDNEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPEVLGQRSTDVVDLENEEPDSDNEW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 QHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILNGILEGASHILPAFRVLS
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_001 QHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILKGILEGASHILPAFRVLS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 SLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 CTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 SRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 ALAAICTAPVGLPDCWDAKEQVCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALAAICTAPVGLPDCWDAKEQVCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 CCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEESTEVTLYFLTLLVFRLQNLPCGM
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
NP_001 CCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEESTEVTLYFLSLLVFRLQNLPCGM
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 EKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAE---
790 800 810 820 830
850 860 870 880 890 900
pF1KE1 TPPGSCGFYDGLLILLLQLLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEG
::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------------LLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEG
840 850 860 870
910 920 930 940 950 960
pF1KE1 ELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLC
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KE1 PSFLNQLRQAPHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSFLNQLRQAPHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQV
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KE1 CCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSD
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KE1 LLSLLAHTARVLSPSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSLLAHTARVLSPSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHS
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KE1 MALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQL
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KE1 LGDPQAGIRRNVASALGNLGPEGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDPQAGIRRNVASALGNLGPEGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL
1180 1190 1200 1210 1220 1230
1270 1280 1290 1300 1310
pF1KE1 QQEPGIHQVLVSLGASEKLSLLSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQEPGIHQVLVSLGASEKLSLLSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
1240 1250 1260 1270 1280 1290
>>XP_016859293 (OMIM: 607652) PREDICTED: serine/threonin (1294 aa)
initn: 5591 init1: 5556 opt: 5560 Z-score: 2600.6 bits: 493.5 E(85289): 4.1e-138
Smith-Waterman score: 8490; 98.2% identity (98.4% similar) in 1315 aa overlap (1-1315:1-1294)
10 20 30 40 50 60
pF1KE1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKDFLQGLLTKDPR
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_016 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPEVLGQRSTDVVDLENEEPDSDNEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPEVLGQRSTDVVDLENEEPDSDNEW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 QHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILNGILEGASHILPAFRVLS
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
XP_016 QHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILKGILEGASHILPAFRVLS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 SLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 CTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 SRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 ALAAICTAPVGLPDCWDAKEQVCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALAAICTAPVGLPDCWDAKEQVCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 CCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEESTEVTLYFLTLLVFRLQNLPCGM
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
XP_016 CCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEESTEVTLYFLSLLVFRLQNLPCGM
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 EKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAE---
790 800 810 820 830
850 860 870 880 890 900
pF1KE1 TPPGSCGFYDGLLILLLQLLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEG
::::::::::::::::::::::::::::::::::::::::::
XP_016 ------------------LLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEG
840 850 860 870
910 920 930 940 950 960
pF1KE1 ELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLC
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KE1 PSFLNQLRQAPHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSFLNQLRQAPHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQV
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KE1 CCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSD
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KE1 LLSLLAHTARVLSPSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSLLAHTARVLSPSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHS
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KE1 MALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQL
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KE1 LGDPQAGIRRNVASALGNLGPEGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGDPQAGIRRNVASALGNLGPEGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL
1180 1190 1200 1210 1220 1230
1270 1280 1290 1300 1310
pF1KE1 QQEPGIHQVLVSLGASEKLSLLSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQEPGIHQVLVSLGASEKLSLLSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
1240 1250 1260 1270 1280 1290
>>XP_011509261 (OMIM: 607652) PREDICTED: serine/threonin (1306 aa)
initn: 5178 init1: 5178 opt: 5180 Z-score: 2424.7 bits: 460.9 E(85289): 2.6e-128
Smith-Waterman score: 8591; 99.1% identity (99.3% similar) in 1315 aa overlap (1-1315:1-1306)
10 20 30 40 50 60
pF1KE1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKDFLQGLLTKDPR
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_011 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPEVLGQRSTDVVDLENEEPDSDNEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPEVLGQRSTDVVDLENEEPDSDNEW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 QHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILNGILEGASHILPAFRVLS
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
XP_011 QHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILKGILEGASHILPAFRVLS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 SLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFA
:::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 SLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQ---------DLMAVIQAYFA
490 500 510 520 530
550 560 570 580 590 600
pF1KE1 CTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGN
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE1 SRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISS
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE1 ALAAICTAPVGLPDCWDAKEQVCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALAAICTAPVGLPDCWDAKEQVCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYS
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE1 CCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEESTEVTLYFLTLLVFRLQNLPCGM
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
XP_011 CCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEESTEVTLYFLSLLVFRLQNLPCGM
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE1 EKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRL
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE1 TPPGSCGFYDGLLILLLQLLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPPGSCGFYDGLLILLLQLLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEG
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE1 ELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLC
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE1 PSFLNQLRQAPHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSFLNQLRQAPHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQV
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE1 CCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSD
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE1 LLSLLAHTARVLSPSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSLLAHTARVLSPSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHS
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE1 MALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQL
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE1 LGDPQAGIRRNVASALGNLGPEGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGDPQAGIRRNVASALGNLGPEGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310
pF1KE1 QQEPGIHQVLVSLGASEKLSLLSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQEPGIHQVLVSLGASEKLSLLSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
1260 1270 1280 1290 1300
>>XP_011509263 (OMIM: 607652) PREDICTED: serine/threonin (784 aa)
initn: 5157 init1: 5157 opt: 5157 Z-score: 2416.0 bits: 458.6 E(85289): 7.8e-128
Smith-Waterman score: 5157; 99.9% identity (100.0% similar) in 784 aa overlap (532-1315:1-784)
510 520 530 540 550 560
pF1KE1 PGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFACTFNLERSQTSDSLQVFQEAA
::::::::::::::::::::::::::::::
XP_011 MAVIQAYFACTFNLERSQTSDSLQVFQEAA
10 20 30
570 580 590 600 610 620
pF1KE1 NLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGNSRAISKAFYSSLLTTQQVVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGNSRAISKAFYSSLLTTQQVVLD
40 50 60 70 80 90
630 640 650 660 670 680
pF1KE1 GLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISSALAAICTAPVGLPDCWDAKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISSALAAICTAPVGLPDCWDAKEQ
100 110 120 130 140 150
690 700 710 720 730 740
pF1KE1 VCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYSCCLVSEGLCRLLGQEPLALES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYSCCLVSEGLCRLLGQEPLALES
160 170 180 190 200 210
750 760 770 780 790 800
pF1KE1 LFMLIQGKVKVVDWEESTEVTLYFLTLLVFRLQNLPCGMEKLGSDVATLFTHSHVVSLVS
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
XP_011 LFMLIQGKVKVVDWEESTEVTLYFLSLLVFRLQNLPCGMEKLGSDVATLFTHSHVVSLVS
220 230 240 250 260 270
810 820 830 840 850 860
pF1KE1 AAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRLTPPGSCGFYDGLLILLLQLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRLTPPGSCGFYDGLLILLLQLLT
280 290 300 310 320 330
870 880 890 900 910 920
pF1KE1 EQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEGELSLSSPPSPEPDWTLISPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEGELSLSSPPSPEPDWTLISPQG
340 350 360 370 380 390
930 940 950 960 970 980
pF1KE1 MAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLCPSFLNQLRQAPHGSEFLPVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLCPSFLNQLRQAPHGSEFLPVVV
400 410 420 430 440 450
990 1000 1010 1020 1030 1040
pF1KE1 LSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQVCCYHLPLMQVELPISLLTRLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQVCCYHLPLMQVELPISLLTRLA
460 470 480 490 500 510
1050 1060 1070 1080 1090 1100
pF1KE1 LMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSDLLSLLAHTARVLSPSHLSFIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSDLLSLLAHTARVLSPSHLSFIQ
520 530 540 550 560 570
1110 1120 1130 1140 1150 1160
pF1KE1 ELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHSMALRGALQSQSGLLSLLLLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHSMALRGALQSQSGLLSLLLLGL
580 590 600 610 620 630
1170 1180 1190 1200 1210 1220
pF1KE1 GDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDPQAGIRRNVASALGNLGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDPQAGIRRNVASALGNLGP
640 650 660 670 680 690
1230 1240 1250 1260 1270 1280
pF1KE1 EGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSLQQEPGIHQVLVSLGASEKLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSLQQEPGIHQVLVSLGASEKLSL
700 710 720 730 740 750
1290 1300 1310
pF1KE1 LSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
::::::::::::::::::::::::::::::::::
XP_011 LSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
760 770 780
>>XP_016859294 (OMIM: 607652) PREDICTED: serine/threonin (784 aa)
initn: 5157 init1: 5157 opt: 5157 Z-score: 2416.0 bits: 458.6 E(85289): 7.8e-128
Smith-Waterman score: 5157; 99.9% identity (100.0% similar) in 784 aa overlap (532-1315:1-784)
510 520 530 540 550 560
pF1KE1 PGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFACTFNLERSQTSDSLQVFQEAA
::::::::::::::::::::::::::::::
XP_016 MAVIQAYFACTFNLERSQTSDSLQVFQEAA
10 20 30
570 580 590 600 610 620
pF1KE1 NLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGNSRAISKAFYSSLLTTQQVVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGNSRAISKAFYSSLLTTQQVVLD
40 50 60 70 80 90
630 640 650 660 670 680
pF1KE1 GLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISSALAAICTAPVGLPDCWDAKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISSALAAICTAPVGLPDCWDAKEQ
100 110 120 130 140 150
690 700 710 720 730 740
pF1KE1 VCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYSCCLVSEGLCRLLGQEPLALES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYSCCLVSEGLCRLLGQEPLALES
160 170 180 190 200 210
750 760 770 780 790 800
pF1KE1 LFMLIQGKVKVVDWEESTEVTLYFLTLLVFRLQNLPCGMEKLGSDVATLFTHSHVVSLVS
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
XP_016 LFMLIQGKVKVVDWEESTEVTLYFLSLLVFRLQNLPCGMEKLGSDVATLFTHSHVVSLVS
220 230 240 250 260 270
810 820 830 840 850 860
pF1KE1 AAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRLTPPGSCGFYDGLLILLLQLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRLTPPGSCGFYDGLLILLLQLLT
280 290 300 310 320 330
870 880 890 900 910 920
pF1KE1 EQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEGELSLSSPPSPEPDWTLISPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEGELSLSSPPSPEPDWTLISPQG
340 350 360 370 380 390
930 940 950 960 970 980
pF1KE1 MAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLCPSFLNQLRQAPHGSEFLPVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLCPSFLNQLRQAPHGSEFLPVVV
400 410 420 430 440 450
990 1000 1010 1020 1030 1040
pF1KE1 LSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQVCCYHLPLMQVELPISLLTRLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQVCCYHLPLMQVELPISLLTRLA
460 470 480 490 500 510
1050 1060 1070 1080 1090 1100
pF1KE1 LMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSDLLSLLAHTARVLSPSHLSFIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSDLLSLLAHTARVLSPSHLSFIQ
520 530 540 550 560 570
1110 1120 1130 1140 1150 1160
pF1KE1 ELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHSMALRGALQSQSGLLSLLLLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHSMALRGALQSQSGLLSLLLLGL
580 590 600 610 620 630
1170 1180 1190 1200 1210 1220
pF1KE1 GDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDPQAGIRRNVASALGNLGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDPQAGIRRNVASALGNLGP
640 650 660 670 680 690
1230 1240 1250 1260 1270 1280
pF1KE1 EGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSLQQEPGIHQVLVSLGASEKLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSLQQEPGIHQVLVSLGASEKLSL
700 710 720 730 740 750
1290 1300 1310
pF1KE1 LSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
::::::::::::::::::::::::::::::::::
XP_016 LSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
760 770 780
>>NP_001271293 (OMIM: 613472) serine/threonine-protein k (470 aa)
initn: 521 init1: 175 opt: 587 Z-score: 302.4 bits: 66.8 E(85289): 4.2e-10
Smith-Waterman score: 587; 38.3% identity (66.0% similar) in 282 aa overlap (1-270:11-282)
10 20 30 40
pF1KE1 MEKYHVLEMIGEGSFGRVYKGR-RKYSAQVVALKFIPKLGRSEKELRNLQ
.. . . : .: :... :::. .: . .:::.: . : . .. ..::
NP_001 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 REIEIMRGLRHPNIVHMLDSFETDKE-VVVVTDY-AEGELFQILEDDGKLPEDQVQAIAA
::::..:.:::.::.. : :. :.. . .. .. : :.: .... ::: ....
NP_001 TEIEILKGIRHPHIVQLKD-FQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQ
70 80 90 100 110
110 120 130 140 150 160
pF1KE1 QLVSALYYLHSHRILHRDMKPQNILLA--KGGGIKLCDFGFARAMST--NTMVLTSIKGT
::.::: .:: . : : :.:::::::. . .:: :::::. :: . :: .:.
NP_001 QLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVL---RGS
120 130 140 150 160 170
170 180 190 200 210
pF1KE1 PLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYATSIFQL-----VSLILKDPVR
::::.::.: .: :: .::::.: :::: : ::: . :. .: . ... :.:
NP_001 PLYMAPEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLR
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE1 WPSTISPCFKDFLQGLLTKDPRQRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLP
: : .:.:: :: .:: .:.:. :.. ::. : . :.: .::
NP_001 -PLLSRDC-RDLLQRLLERDPSRRISFQDFFAHPW----VDLEHMPSGESLGRATALVVQ
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE1 PELQVLKDEQAHRLAPKGNQSRILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGT
NP_001 AVKKDQEGDSAAALSLYCKALDFFVPALHYEVDAQRKEAIKAKVGQYVSRAEELKAIVSS
300 310 320 330 340 350
>>NP_001092906 (OMIM: 613472) serine/threonine-protein k (472 aa)
initn: 521 init1: 175 opt: 587 Z-score: 302.4 bits: 66.8 E(85289): 4.2e-10
Smith-Waterman score: 587; 38.3% identity (66.0% similar) in 282 aa overlap (1-270:11-282)
10 20 30 40
pF1KE1 MEKYHVLEMIGEGSFGRVYKGR-RKYSAQVVALKFIPKLGRSEKELRNLQ
.. . . : .: :... :::. .: . .:::.: . : . .. ..::
NP_001 MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 REIEIMRGLRHPNIVHMLDSFETDKE-VVVVTDY-AEGELFQILEDDGKLPEDQVQAIAA
::::..:.:::.::.. : :. :.. . .. .. : :.: .... ::: ....
NP_001 TEIEILKGIRHPHIVQLKD-FQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQ
70 80 90 100 110
110 120 130 140 150 160
pF1KE1 QLVSALYYLHSHRILHRDMKPQNILLA--KGGGIKLCDFGFARAMST--NTMVLTSIKGT
::.::: .:: . : : :.:::::::. . .:: :::::. :: . :: .:.
NP_001 QLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVL---RGS
120 130 140 150 160 170
170 180 190 200 210
pF1KE1 PLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYATSIFQL-----VSLILKDPVR
::::.::.: .: :: .::::.: :::: : ::: . :. .: . ... :.:
NP_001 PLYMAPEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLR
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE1 WPSTISPCFKDFLQGLLTKDPRQRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLP
: : .:.:: :: .:: .:.:. :.. ::. : . :.: .::
NP_001 -PLLSRDC-RDLLQRLLERDPSRRISFQDFFAHPW----VDLEHMPSGESLGRATALVVQ
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE1 PELQVLKDEQAHRLAPKGNQSRILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGT
NP_001 AVKKDQEGDSAAALSLYCKALDFFVPALHYEVDAQRKEAIKAKVGQYVSRAEELKAIVSS
300 310 320 330 340 350
1315 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:29:13 2016 done: Mon Nov 7 00:29:15 2016
Total Scan time: 17.990 Total Display time: 0.440
Function used was FASTA [36.3.4 Apr, 2011]