FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1420, 209 aa
  1>>>pF1KE1420 209 - 209 aa - 209 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.8702+/-0.000322; mu= -5.3369+/- 0.020
 mean_var=278.8373+/-57.318, 0's: 0 Z-trim(125.4): 47  B-trim: 840 in 1/61
 Lambda= 0.076807
 statistics sampled from 48996 (49056) to 48996 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.855), E-opt: 0.2 (0.575), width:  16
 Scan time:  7.380

The best scores are:                                      opt bits E(85289)
NP_061986 (OMIM: 609436) fibroblast growth factor  ( 209) 1445 171.9 6.6e-43
NP_005108 (OMIM: 603891) fibroblast growth factor  ( 216)  371 52.9 4.5e-07
NP_065689 (OMIM: 193100,605380) fibroblast growth  ( 251)  312 46.4 4.7e-05


>>NP_061986 (OMIM: 609436) fibroblast growth factor 21 p  (209 aa)
 initn: 1445 init1: 1445 opt: 1445  Z-score: 891.3  bits: 171.9 E(85289): 6.6e-43
Smith-Waterman score: 1445; 99.5% identity (99.5% similar) in 209 aa overlap (1-209:1-209)

               10        20        30        40        50        60
pF1KE1 MDSDETGFEHSGLWVSVLAGLLLGACQAHPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MDSDETGFEHSGLWVSVLAGLLLGACQAHPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 LEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 CSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPAPPEPPGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
NP_061 CSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPALPEPPGI
              130       140       150       160       170       180

              190       200         
pF1KE1 LAPQPPDVGSSDPLSMVGPSQGRSPSYAS
       :::::::::::::::::::::::::::::
NP_061 LAPQPPDVGSSDPLSMVGPSQGRSPSYAS
              190       200         

>>NP_005108 (OMIM: 603891) fibroblast growth factor 19 p  (216 aa)
 initn: 294 init1: 273 opt: 371  Z-score: 247.9  bits: 52.9 E(85289): 4.5e-07
Smith-Waterman score: 371; 37.7% identity (61.8% similar) in 212 aa overlap (13-207:10-214)

               10        20        30          40          50      
pF1KE1 MDSDETGFEHSGLWVSVLAGLLLGACQAHPIP--DSSPLLQFG-GQ-VRQRYLYTDDAQQ
                   .:.  :::: : :  ..:.   :..: ...: :. .: :.:::.  . 
NP_005    MRSGCVVVHVWI--LAGLWL-AVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHG
                  10           20        30        40        50    

          60        70        80        90       100       110     
pF1KE1 -TEAHLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLH
        .   :.:: ::.:  :  :: .:::..::.   .. : ::.. :.::.  :: . : :.
NP_005 LSSCFLRIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQ
           60        70        80        90       100       110    

         120       130       140       150       160           170 
pF1KE1 FDPEACSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPL----PGLP
       .. : :.:.: .  ::::::.:: : ::. : . :. ..    ::   ::::    : ::
NP_005 YSEEDCAFEEEIRPDGYNVYRSEKHRLPVSLSSAKQ-RQLYKNRG---FLPLSHFLPMLP
          120       130       140       150           160       170

             180              190        200         
pF1KE1 PAPPEPPGI-------LAPQPPDVGSSDPLSMV-GPSQGRSPSYAS
        .: ::  .       .  .: .. : ::...: :    ::::.  
NP_005 MVPEEPEDLRGHLESDMFSSPLETDSMDPFGLVTGLEAVRSPSFEK
              180       190       200       210      

>>NP_065689 (OMIM: 193100,605380) fibroblast growth fact  (251 aa)
 initn: 279 init1: 228 opt: 312  Z-score: 211.7  bits: 46.4 E(85289): 4.7e-05
Smith-Waterman score: 312; 32.2% identity (57.6% similar) in 205 aa overlap (13-209:8-205)

               10        20         30          40        50       
pF1KE1 MDSDETGFEHSGLWVSVLAGLL-LGACQAHPIPDSSPLL--QFGGQVRQRYLYTDDAQQT
                   ::: .: ..  ... .:.:  ..::::  ..:: .   .:::  :...
NP_065      MLGARLRLWVCALCSVCSMSVLRAYP--NASPLLGSSWGGLI---HLYTATARNS
                    10        20          30        40           50

        60        70        80        90       100       110       
pF1KE1 EAHLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFD
         ::.:...: : ::  :.  : :....   : . : :: . :.::.   : ..:: .::
NP_065 Y-HLQIHKNGHVDGAPHQTIYSALMIRSEDAGFVVITGVMSRRYLCMDFRGNIFGSHYFD
                60        70        80        90       100         

       120       130       140       150          160         170  
pF1KE1 PEACSFRELLLEDGYNVYQSEAHGLPLHLPGNKS---PHRDPAPRGP--ARFLPLPGLPP
       :: : :..  ::.::.::.:  . . . :   :    :  .: : .   .:   .: .  
NP_065 PENCRFQHQTLENGYDVYHSPQYHFLVSLGRAKRAFLPGMNPPPYSQFLSRRNEIPLIHF
     110       120       130       140       150       160         

            180       190       200                                
pF1KE1 APPEPPGILAPQPPDVGSSDPLSMVGPSQGRSPSYAS                       
         : :         : .  :::... :    .:. ::                       
NP_065 NTPIPRRHTRSAEDD-SERDPLNVLKPRARMTPAPASCSQELPSAEDNSPMASDPLGVVR
     170       180        190       200       210       220        

NP_065 GGRVNTHAGGTGPEGCRPFAKFI
      230       240       250 




209 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 22:46:35 2016 done: Sun Nov  6 22:46:36 2016
 Total Scan time:  7.380 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]