Result of FASTA (omim) for
pFN21AE1407
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1407, 325 aa
1>>>pF1KE1407 325 - 325 aa - 325 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9409+/-0.000319; mu= 18.1210+/- 0.020
mean_var=74.8280+/-15.290, 0's: 0 Z-trim(116.8): 66 B-trim: 0 in 0/50
Lambda= 0.148266
statistics sampled from 28108 (28175) to 28108 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.704), E-opt: 0.2 (0.33), width: 16
Scan time: 6.500
The best scores are: opt bits E(85289)
NP_000619 (OMIM: 123889,610424,612567) interleukin ( 325) 2290 499.0 5.6e-141
NP_005525 (OMIM: 147569,614889) interferon gamma r ( 337) 306 74.6 3.3e-13
XP_011527856 (OMIM: 147569,614889) PREDICTED: inte ( 339) 306 74.6 3.3e-13
NP_001316057 (OMIM: 147569,614889) interferon gamm ( 356) 306 74.6 3.4e-13
XP_011527855 (OMIM: 147569,614889) PREDICTED: inte ( 362) 306 74.6 3.4e-13
XP_011527854 (OMIM: 107450) PREDICTED: interferon ( 270) 298 72.8 9.1e-13
NP_000620 (OMIM: 107450) interferon alpha/beta rec ( 557) 298 73.1 1.5e-12
XP_016866444 (OMIM: 605620) PREDICTED: interleukin ( 505) 249 62.6 2.1e-09
XP_016866443 (OMIM: 605620) PREDICTED: interleukin ( 554) 249 62.6 2.2e-09
XP_005261021 (OMIM: 107450) PREDICTED: interferon ( 488) 248 62.3 2.3e-09
NP_001265651 (OMIM: 605620) interleukin-20 recepto ( 504) 248 62.3 2.4e-09
NP_055247 (OMIM: 605620) interleukin-20 receptor s ( 553) 248 62.4 2.5e-09
NP_734464 (OMIM: 607404) interferon lambda recepto ( 520) 199 51.9 3.5e-06
XP_011534206 (OMIM: 605620) PREDICTED: interleukin ( 442) 196 51.2 4.8e-06
NP_001265652 (OMIM: 605620) interleukin-20 recepto ( 442) 195 51.0 5.6e-06
NP_851826 (OMIM: 606648) interleukin-22 receptor s ( 231) 188 49.2 9.8e-06
NP_653318 (OMIM: 605621) interleukin-20 receptor s ( 311) 184 48.5 2.2e-05
NP_775087 (OMIM: 607404) interferon lambda recepto ( 491) 168 45.2 0.00033
XP_006715569 (OMIM: 605620) PREDICTED: interleukin ( 420) 162 43.9 0.00072
NP_001265653 (OMIM: 605620) interleukin-20 recepto ( 420) 161 43.7 0.00083
NP_775088 (OMIM: 607404) interferon lambda recepto ( 244) 158 42.8 0.00087
XP_011511212 (OMIM: 605621) PREDICTED: interleukin ( 316) 159 43.1 0.00091
NP_001549 (OMIM: 146933,613148) interleukin-10 rec ( 578) 151 41.7 0.0046
>>NP_000619 (OMIM: 123889,610424,612567) interleukin-10 (325 aa)
initn: 2290 init1: 2290 opt: 2290 Z-score: 2652.0 bits: 499.0 E(85289): 5.6e-141
Smith-Waterman score: 2290; 100.0% identity (100.0% similar) in 325 aa overlap (1-325:1-325)
10 20 30 40 50 60
pF1KE1 MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IFQDKCMNTTLTECDFSSLSKYGDHTLRVRAEFADEHSDWVNITFCPVDDTIIGPPGMQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IFQDKCMNTTLTECDFSSLSKYGDHTLRVRAEFADEHSDWVNITFCPVDDTIIGPPGMQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDFEVLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDFEVLRN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETVPSWMVAVILMASVFMVCLALLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETVPSWMVAVILMASVFMVCLALLG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 CFALLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHNTLLFFSFPLSDENDVFDKLSVIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CFALLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHNTLLFFSFPLSDENDVFDKLSVIAE
250 260 270 280 290 300
310 320
pF1KE1 DSESGKQNPGDSCSLGTPPGQGPQS
:::::::::::::::::::::::::
NP_000 DSESGKQNPGDSCSLGTPPGQGPQS
310 320
>>NP_005525 (OMIM: 147569,614889) interferon gamma recep (337 aa)
initn: 190 init1: 73 opt: 306 Z-score: 358.2 bits: 74.6 E(85289): 3.3e-13
Smith-Waterman score: 335; 25.7% identity (56.0% similar) in 327 aa overlap (1-299:5-324)
10 20 30 40
pF1KE1 MAWSLGSWLGGCLLVSA-----LGMVPPPENVRMNSVNFKNILQWESPAFAKGN--
. ::: :: ..: :...: :.. .. : ...:.:: :.....
NP_005 MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRP
10 20 30 40 50 60
50 60 70 80 90
pF1KE1 LTFTAQ--YLSYRIFQD-------KCMNTTLTECDFSSLSKYGDH------TLRVRAEFA
... .: : . . : .: . : :::::.. : . :::.:::..
NP_005 VVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAELG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 DEHSDWVNIT-FCPVDDTIIGPP-GMQVEVLADSLHMRFLAPKIENEYETWTMKNVYNSW
:: ::.. : .. .::: ...: :: .:: .: .. .... .
NP_005 ALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSP-----FDIADTSTAF--F
130 140 150 160 170
160 170 180 190 200
pF1KE1 TYNVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRG-FLPDRN---KAGEWSEPV
: :.::..: .. . . . : ::.: .::.::.. .: ... ..:. :.
NP_005 CYYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSNIS
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE1 CEQTTHDETVPSWMVAVILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQHLKE
: .: : .. .: .: ... .. . .:: :. :: : :.: ...:
NP_005 CYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQIEE
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE1 FLGHPHHNTLLFFSFPLSDENDVFDKLSVIAEDSESGKQNPGDSCSLGTPPGQGPQS
.: : . : .. : ..::.:..:.:.
NP_005 YLKDPTQPILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL
300 310 320 330
>>XP_011527856 (OMIM: 147569,614889) PREDICTED: interfer (339 aa)
initn: 273 init1: 97 opt: 306 Z-score: 358.2 bits: 74.6 E(85289): 3.3e-13
Smith-Waterman score: 334; 25.6% identity (57.1% similar) in 308 aa overlap (15-299:26-326)
10 20 30 40
pF1KE1 MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKGN
:. :...: :.. .. : ...:.:: :.....
XP_011 MSTPSSSESVNLGMCCLTYKRDSADVNPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNST
10 20 30 40 50 60
50 60 70 80 90
pF1KE1 --LTFTAQ--YLSYRIFQD-------KCMNTTLTECDFSSLSKYGDH------TLRVRAE
... .: : . . : .: . : :::::.. : . :::.:::
XP_011 RPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAE
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 FADEHSDWVNIT-FCPVDDTIIGPP-GMQVEVLADSLHMRFLAPKIENEYETWTMKNVYN
.. :: ::.. : .. .::: ...: :: .:: .: .. ....
XP_011 LGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSP-----FDIADTSTAF-
130 140 150 160 170
160 170 180 190 200
pF1KE1 SWTYNVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRG-FLPDRN---KAGEWSE
. : :.::..: .. . . . : ::.: .::.::.. .: ... ..:. :.
XP_011 -FCYYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSN
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE1 PVCEQTTHDETVPSWMVAVILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQHL
: .: : .. .: .: ... .. . .:: :. :: : :.: ..
XP_011 ISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQI
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE1 KEFLGHPHHNTLLFFSFPLSDENDVFDKLSVIAEDSESGKQNPGDSCSLGTPPGQGPQS
.:.: : . : .. : ..::.:..:.:.
XP_011 EEYLKDPTQPILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL
300 310 320 330
>>NP_001316057 (OMIM: 147569,614889) interferon gamma re (356 aa)
initn: 190 init1: 73 opt: 306 Z-score: 357.9 bits: 74.6 E(85289): 3.4e-13
Smith-Waterman score: 329; 25.6% identity (57.0% similar) in 305 aa overlap (18-299:46-343)
10 20 30 40
pF1KE1 MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAK
:...: :.. .. : ...:.:: :...
NP_001 FAAAAAAPPAQLTLETYQEWCNDSAATHDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSN
20 30 40 50 60 70
50 60 70 80 90
pF1KE1 GN--LTFTAQ--YLSYRIFQD-------KCMNTTLTECDFSSLSKYGDH------TLRVR
.. ... .: : . . : .: . : :::::.. : . :::.:
NP_001 STRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLR
80 90 100 110 120 130
100 110 120 130 140
pF1KE1 AEFADEHSDWVNIT-FCPVDDTIIGPP-GMQVEVLADSLHMRFLAPKIENEYETWTMKNV
::.. :: ::.. : .. .::: ...: :: .:: .: .. ...
NP_001 AELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSP-----FDIADTSTA
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE1 YNSWTYNVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRG-FLPDRN---KAGEW
. . : :.::..: .. . . . : ::.: .::.::.. .: ... ..:.
NP_001 F--FCYYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHL
200 210 220 230 240
210 220 230 240 250 260
pF1KE1 SEPVCEQTTHDETVPSWMVAVILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQ
:. : .: : .. .: .: ... .. . .:: :. :: : :.:
NP_001 SNISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPL
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE1 HLKEFLGHPHHNTLLFFSFPLSDENDVFDKLSVIAEDSESGKQNPGDSCSLGTPPGQGPQ
...:.: : . : .. : ..::.:..:.:.
NP_001 QIEEYLKDPTQPILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL
310 320 330 340 350
pF1KE1 S
>>XP_011527855 (OMIM: 147569,614889) PREDICTED: interfer (362 aa)
initn: 273 init1: 97 opt: 306 Z-score: 357.8 bits: 74.6 E(85289): 3.4e-13
Smith-Waterman score: 329; 25.6% identity (57.0% similar) in 305 aa overlap (18-299:52-349)
10 20 30 40
pF1KE1 MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAK
:...: :.. .. : ...:.:: :...
XP_011 VPKDVHALILRVREPGNVLPDVQKGLRRYPLSQLPAPQHPKIRLYNAEQVLSWEPVALSN
30 40 50 60 70 80
50 60 70 80 90
pF1KE1 GN--LTFTAQ--YLSYRIFQD-------KCMNTTLTECDFSSLSKYGDH------TLRVR
.. ... .: : . . : .: . : :::::.. : . :::.:
XP_011 STRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLR
90 100 110 120 130 140
100 110 120 130 140
pF1KE1 AEFADEHSDWVNIT-FCPVDDTIIGPP-GMQVEVLADSLHMRFLAPKIENEYETWTMKNV
::.. :: ::.. : .. .::: ...: :: .:: .: .. ...
XP_011 AELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSP-----FDIADTSTA
150 160 170 180 190
150 160 170 180 190 200
pF1KE1 YNSWTYNVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRG-FLPDRN---KAGEW
. . : :.::..: .. . . . : ::.: .::.::.. .: ... ..:.
XP_011 F--FCYYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHL
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE1 SEPVCEQTTHDETVPSWMVAVILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQ
:. : .: : .. .: .: ... .. . .:: :. :: : :.:
XP_011 SNISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPL
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE1 HLKEFLGHPHHNTLLFFSFPLSDENDVFDKLSVIAEDSESGKQNPGDSCSLGTPPGQGPQ
...:.: : . : .. : ..::.:..:.:.
XP_011 QIEEYLKDPTQPILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL
320 330 340 350 360
pF1KE1 S
>>XP_011527854 (OMIM: 107450) PREDICTED: interferon alph (270 aa)
initn: 224 init1: 127 opt: 298 Z-score: 350.2 bits: 72.8 E(85289): 9.1e-13
Smith-Waterman score: 298; 29.9% identity (59.4% similar) in 224 aa overlap (3-219:19-230)
10 20 30 40
pF1KE1 MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPA
: :.. :: : : :..:... .. . ::.:.
XP_011 MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKS-------PQKVEVDIIDDNFILRWNRSD
10 20 30 40 50
50 60 70 80 90
pF1KE1 FAKGNLTFTAQY----LSYRIFQDKCMNTTLTECDFSSL--SKYGDHTLRVRAEFADEHS
. ::.::. .: .. : . :.: : :.:.:::: . : . ::.::: .. :
XP_011 ESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAE-KENTS
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE1 DWVNI-TFCPVDDTIIGPPGMQVEVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQ
.: .. .: : . :::: ...:. :. . ..: .. :.. .. :.::..
XP_011 SWYEVDSFTPFRKAQIGPPEVHLEA-EDKAIVIHISPGTKDSV-MWALDGL--SFTYSLV
120 130 140 150 160
160 170 180 190 200 210
pF1KE1 YWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDET
:::.. . .: :. . . .: : ::::..:.. : : : .: : .:: ..
XP_011 IWKNSSGVEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENE
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE1 VPSWMVAVILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHNT
.:
XP_011 LPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHLYFRRPR
230 240 250 260 270
>>NP_000620 (OMIM: 107450) interferon alpha/beta recepto (557 aa)
initn: 254 init1: 121 opt: 298 Z-score: 346.1 bits: 73.1 E(85289): 1.5e-12
Smith-Waterman score: 330; 25.5% identity (59.9% similar) in 302 aa overlap (23-308:231-521)
10 20 30 40 50
pF1KE1 MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKGNLTF
::::.... : . .:.:. .. .:.::
NP_000 KVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWD---YTYANMTF
210 220 230 240 250
60 70 80 90
pF1KE1 TAQYLS-----------YRIFQ-DKCMNTTLTECDF-SSLSKYGDHTLRVRAEFADEHSD
.:.: :. : : :. :.: : ... . : . :::.: ... :
NP_000 QVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSF
260 270 280 290 300 310
100 110 120 130 140 150
pF1KE1 WVN-ITFCPVDDTIIGPPGMQVEVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQY
: . : : .... :: .... :.::.:. . ::: . .: .... :.. .
NP_000 WSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSG--NTPVIQDY--PLIYEIIF
320 330 340 350 360 370
160 170 180 190 200 210
pF1KE1 WKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLPDR--NKAGEWSEPVCEQTTHDE
:.: .. . .: . .. ::.: :.:::..:. :. ::.. .:. :::.: .
NP_000 WENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGN
380 390 400 410 420 430
220 230 240 250 260 270
pF1KE1 TVPSWMVAVILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHN
: :... : .: .: . ... . ..: :. ...: .:. ....: .: .:
NP_000 TSKIWLIVGICIA-LFALPFVIYAAKVFLRCINYVFFPSLKPSSSIDEYFSE---QPLKN
440 450 460 470 480
280 290 300 310 320
pF1KE1 TLLFFSFPLSDENDVFDKLSVIAEDSESGKQNPGDSCSLGTPPGQGPQS
:: : .. .....:.:: :... .
NP_000 LLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNYSNEDESESKTS
490 500 510 520 530 540
NP_000 EELQQDFV
550
>--
initn: 254 init1: 121 opt: 298 Z-score: 346.1 bits: 73.1 E(85289): 1.5e-12
Smith-Waterman score: 298; 29.9% identity (59.4% similar) in 224 aa overlap (3-219:19-230)
10 20 30 40
pF1KE1 MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPA
: :.. :: : : :..:... .. . ::.:.
NP_000 MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKS-------PQKVEVDIIDDNFILRWNRSD
10 20 30 40 50
50 60 70 80 90
pF1KE1 FAKGNLTFTAQY----LSYRIFQDKCMNTTLTECDFSSL--SKYGDHTLRVRAEFADEHS
. ::.::. .: .. : . :.: : :.:.:::: . : . ::.::: .. :
NP_000 ESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAE-KENTS
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE1 DWVNI-TFCPVDDTIIGPPGMQVEVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQ
.: .. .: : . :::: ...:. :. . ..: .. :.. .. :.::..
NP_000 SWYEVDSFTPFRKAQIGPPEVHLEA-EDKAIVIHISPGTKDSV-MWALDGL--SFTYSLV
120 130 140 150 160
160 170 180 190 200 210
pF1KE1 YWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDET
:::.. . .: :. . . .: : ::::..:.. : : : .: : .:: ..
NP_000 IWKNSSGVEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENE
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE1 VPSWMVAVILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHNT
.:
NP_000 LPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKT
230 240 250 260 270 280
>>XP_016866444 (OMIM: 605620) PREDICTED: interleukin-20 (505 aa)
initn: 225 init1: 131 opt: 249 Z-score: 290.0 bits: 62.6 E(85289): 2.1e-09
Smith-Waterman score: 299; 26.2% identity (57.0% similar) in 309 aa overlap (35-319:2-303)
10 20 30 40 50 60
pF1KE1 LGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKG-NLTFTAQYLSYRIFQ
::.::: : .: ..:.:.::. : :
XP_016 MKNVLQWTPPEGLQGVKVTYTVQYF-IRYGQ
10 20 30
70 80 90 100 110
pF1KE1 DK------CMNTTLTECDFSSLSKYGDHTL--RVRAEFADEHSDWVNI-TFCPVDDTIIG
: : : . : ::.:. .. .: .:.: .. . : :.. : : .: ::
XP_016 KKWLNKSECRNINRTYCDLSAETSDYEHQYYAKVKAIWGTKCSKWAESGRFYPFLETQIG
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 PPGMQVEVLADSLHMRFLAP---KIENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITP
:: . . . :. . . :: : . : .:...:.. :::. .. ... ..
XP_016 PPEVALTTDEKSISVVLTAPEKWKRNPEDLPVSMQQIYSNLKYNVSVLNTKSNRTWSQCV
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 QYDFEVLRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETVPSWMVAVILMASV
:: ::: : :::.:..:.: . .. :: : .: .:.. : . : :.. :
XP_016 TNHTLVLTWLEPNTLYCVHVESFVPGPPRRAQPSEKQCARTLKDQS--SEFKAKIIFWYV
160 170 180 190 200
240 250 260 270 280
pF1KE1 FMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQHL---------KEFLGHPHHNTLLFFS
. : .... .. . .:. : ... : .: :.:. .. .. :..
XP_016 LPVSITVFLFSVMGYSIYR---YIHVGKEKHPANLILIYGNEFDKRFFVPAEKIVINFIT
210 220 230 240 250 260
290 300 310 320
pF1KE1 FPLSDENDVFDK-LSVIAEDSE-SGKQNPGDSCSLGTPPGQGPQS
. .::.. . . .:.....:. :. ..: : .: ::
XP_016 LNISDDSKISHQDMSLLGKSSDVSSLNDPQPSGNL-RPPQEEEEVKHLGYASHLMEIFCD
270 280 290 300 310 320
XP_016 SEENTEGTSLTQQESLSRTIPPDKTVIEYEYDVRTTDICAGPEEQELSLQEEVSTQGTLL
330 340 350 360 370 380
>>XP_016866443 (OMIM: 605620) PREDICTED: interleukin-20 (554 aa)
initn: 225 init1: 131 opt: 249 Z-score: 289.5 bits: 62.6 E(85289): 2.2e-09
Smith-Waterman score: 345; 26.8% identity (57.5% similar) in 325 aa overlap (19-319:35-352)
10 20 30 40
pF1KE1 MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKG
: .: : :. . :.:.::.::: : .:
XP_016 GRPALRPLPLPPLLLLLLAAPWGRAVPCVSGGLPKPANITFLSINMKNVLQWTPPEGLQG
10 20 30 40 50 60
50 60 70 80 90
pF1KE1 -NLTFTAQYLSYRIFQDK------CMNTTLTECDFSSLSKYGDHTL--RVRAEFADEHSD
..:.:.::. : : : : : . : ::.:. .. .: .:.: .. . :
XP_016 VKVTYTVQYF-IRYGQKKWLNKSECRNINRTYCDLSAETSDYEHQYYAKVKAIWGTKCSK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 WVNI-TFCPVDDTIIGPPGMQVEVLADSLHMRFLAP---KIENEYETWTMKNVYNSWTYN
:.. : : .: :::: . . . :. . . :: : . : .:...:.. ::
XP_016 WAESGRFYPFLETQIGPPEVALTTDEKSISVVLTAPEKWKRNPEDLPVSMQQIYSNLKYN
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE1 VQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHD
:. .. ... .. :: ::: : :::.:..:.: . .. :: : .: .:
XP_016 VSVLNTKSNRTWSQCVTNHTLVLTWLEPNTLYCVHVESFVPGPPRRAQPSEKQCARTLKD
190 200 210 220 230 240
220 230 240 250 260
pF1KE1 ETVPSWMVAVILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQHL---------
.. : . : :.. :. : .... .. . .: .: ... : .:
XP_016 QS--SEFKAKIIFWYVLPVSITVFLFSVMGYSIY---RYIHVGKEKHPANLILIYGNEFD
250 260 270 280 290
270 280 290 300 310 320
pF1KE1 KEFLGHPHHNTLLFFSFPLSDENDVFDK-LSVIAEDSE-SGKQNPGDSCSLGTPPGQGPQ
:.:. .. .. :... .::.. . . .:.....:. :. ..: : .: ::
XP_016 KRFFVPAEKIVINFITLNISDDSKISHQDMSLLGKSSDVSSLNDPQPSGNL-RPPQEEEE
300 310 320 330 340 350
pF1KE1 S
XP_016 VKHLGYASHLMEIFCDSEENTEGTSLTQQESLSRTIPPDKTVIEYEYDVRTTDICAGPEE
360 370 380 390 400 410
>>XP_005261021 (OMIM: 107450) PREDICTED: interferon alph (488 aa)
initn: 215 init1: 121 opt: 248 Z-score: 289.0 bits: 62.3 E(85289): 2.3e-09
Smith-Waterman score: 330; 25.5% identity (59.9% similar) in 302 aa overlap (23-308:162-452)
10 20 30 40 50
pF1KE1 MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKGNLTF
::::.... : . .:.:. .. .:.::
XP_005 KVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWD---YTYANMTF
140 150 160 170 180
60 70 80 90
pF1KE1 TAQYLS-----------YRIFQ-DKCMNTTLTECDF-SSLSKYGDHTLRVRAEFADEHSD
.:.: :. : : :. :.: : ... . : . :::.: ... :
XP_005 QVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSF
190 200 210 220 230 240
100 110 120 130 140 150
pF1KE1 WVN-ITFCPVDDTIIGPPGMQVEVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQY
: . : : .... :: .... :.::.:. . ::: . .: .... :.. .
XP_005 WSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSG--NTPVIQDY--PLIYEIIF
250 260 270 280 290 300
160 170 180 190 200 210
pF1KE1 WKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLPDR--NKAGEWSEPVCEQTTHDE
:.: .. . .: . .. ::.: :.:::..:. :. ::.. .:. :::.: .
XP_005 WENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGN
310 320 330 340 350 360
220 230 240 250 260 270
pF1KE1 TVPSWMVAVILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHN
: :... : .: .: . ... . ..: :. ...: .:. ....: .: .:
XP_005 TSKIWLIVGICIA-LFALPFVIYAAKVFLRCINYVFFPSLKPSSSIDEYFSE---QPLKN
370 380 390 400 410 420
280 290 300 310 320
pF1KE1 TLLFFSFPLSDENDVFDKLSVIAEDSESGKQNPGDSCSLGTPPGQGPQS
:: : .. .....:.:: :... .
XP_005 LLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNYSNEDESESKTS
430 440 450 460 470 480
XP_005 EELQQDFV
>--
initn: 215 init1: 121 opt: 248 Z-score: 289.0 bits: 62.3 E(85289): 2.3e-09
Smith-Waterman score: 248; 31.8% identity (61.8% similar) in 157 aa overlap (66-219:10-161)
40 50 60 70 80 90
pF1KE1 NILQWESPAFAKGNLTFTAQYLSYRIFQDKCMNTTLTECDFSSL--SKYGDHTLRVRAEF
:.: : :.:.:::: . : . ::.:::
XP_005 MDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAE-
10 20 30
100 110 120 130 140 150
pF1KE1 ADEHSDWVNI-TFCPVDDTIIGPPGMQVEVLADSLHMRFLAPKIENEYETWTMKNVYNSW
.. :.: .. .: : . :::: ...:. :. . ..: .. :.. .. :.
XP_005 KENTSSWYEVDSFTPFRKAQIGPPEVHLEA-EDKAIVIHISPGTKDSV-MWALDGL--SF
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE1 TYNVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQT
::.. :::.. . .: :. . . .: : ::::..:.. : : : .: : .:
XP_005 TYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKT
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE1 THDETVPSWMVAVILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQHLKEFLGH
: .. .:
XP_005 TVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDC
160 170 180 190 200 210
325 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:46:25 2016 done: Mon Nov 7 02:46:26 2016
Total Scan time: 6.500 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]