Result of FASTA (omim) for
pFN21AE1403
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1403, 374 aa
1>>>pF1KE1403 374 - 374 aa - 374 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8699+/-0.000533; mu= 19.4114+/- 0.033
mean_var=106.3067+/-26.943, 0's: 0 Z-trim(107.0): 691 B-trim: 938 in 1/47
Lambda= 0.124392
statistics sampled from 14272 (15046) to 14272 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.502), E-opt: 0.2 (0.176), width: 16
Scan time: 7.090
The best scores are: opt bits E(85289)
NP_113597 (OMIM: 601835) C-C chemokine receptor ty ( 374) 2453 452.0 1e-126
NP_004358 (OMIM: 601835) C-C chemokine receptor ty ( 374) 2453 452.0 1e-126
NP_001288647 (OMIM: 600242) C-C chemokine receptor ( 372) 955 183.1 8.7e-46
NP_001288646 (OMIM: 600242) C-C chemokine receptor ( 372) 955 183.1 8.7e-46
NP_001288645 (OMIM: 600242) C-C chemokine receptor ( 372) 955 183.1 8.7e-46
NP_001829 (OMIM: 600242) C-C chemokine receptor ty ( 378) 955 183.2 8.8e-46
NP_001288643 (OMIM: 600242) C-C chemokine receptor ( 315) 881 169.8 7.8e-42
NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 880 169.7 9.6e-42
XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 880 169.7 9.6e-42
NP_000625 (OMIM: 146929,609423) C-X-C chemokine re ( 350) 877 169.1 1.4e-41
NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 853 164.8 2.8e-40
XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 853 164.8 2.8e-40
XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 853 164.8 2.8e-40
XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 853 164.8 2.8e-40
XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 853 164.8 2.8e-40
NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 853 164.8 2.8e-40
NP_112477 (OMIM: 604738) C-C chemokine receptor ty ( 369) 837 162.0 2.1e-39
XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369) 837 162.0 2.1e-39
NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357) 832 161.1 3.8e-39
NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 832 161.1 3.8e-39
NP_001495 (OMIM: 300574) C-X-C chemokine receptor ( 368) 750 146.4 1e-34
XP_005262313 (OMIM: 300574) PREDICTED: C-X-C chemo ( 378) 750 146.4 1e-34
XP_016884924 (OMIM: 300574) PREDICTED: C-X-C chemo ( 415) 750 146.4 1.1e-34
NP_001136269 (OMIM: 300574) C-X-C chemokine recept ( 415) 750 146.4 1.1e-34
NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 749 146.2 1.1e-34
XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 742 144.9 2.7e-34
NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 742 144.9 2.7e-34
NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 742 144.9 2.7e-34
XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 742 144.9 2.7e-34
NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 742 144.9 2.8e-34
NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 742 144.9 2.8e-34
XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 742 145.0 3e-34
XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 742 145.0 3e-34
NP_001116868 (OMIM: 601267) C-C chemokine receptor ( 360) 738 144.2 4.5e-34
XP_011532371 (OMIM: 601267) PREDICTED: C-C chemoki ( 360) 738 144.2 4.5e-34
NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 736 143.8 5.7e-34
NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 736 143.8 5.7e-34
NP_001116513 (OMIM: 601267) C-C chemokine receptor ( 374) 735 143.7 6.7e-34
NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 726 142.1 2.1e-33
NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 723 141.5 2.9e-33
NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 697 136.8 7.3e-32
NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 697 136.8 7.4e-32
NP_001164643 (OMIM: 601470,607339,609423,613784) C ( 355) 696 136.6 8.3e-32
NP_001164642 (OMIM: 601470,607339,609423,613784) C ( 355) 696 136.6 8.3e-32
NP_001328 (OMIM: 601470,607339,609423,613784) CX3C ( 355) 696 136.6 8.3e-32
NP_001164645 (OMIM: 601470,607339,609423,613784) C ( 387) 696 136.7 8.8e-32
NP_001707 (OMIM: 601613) C-X-C chemokine receptor ( 372) 666 131.3 3.6e-30
NP_116743 (OMIM: 601613) C-X-C chemokine receptor ( 327) 659 130.0 7.9e-30
NP_057686 (OMIM: 600240) C-C chemokine receptor ty ( 362) 650 128.4 2.6e-29
XP_011531593 (OMIM: 605163) PREDICTED: C-X-C chemo ( 342) 636 125.9 1.4e-28
>>NP_113597 (OMIM: 601835) C-C chemokine receptor type 6 (374 aa)
initn: 2453 init1: 2453 opt: 2453 Z-score: 2395.8 bits: 452.0 E(85289): 1e-126
Smith-Waterman score: 2453; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374)
10 20 30 40 50 60
pF1KE1 MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT
310 320 330 340 350 360
370
pF1KE1 SETADNDNASSFTM
::::::::::::::
NP_113 SETADNDNASSFTM
370
>>NP_004358 (OMIM: 601835) C-C chemokine receptor type 6 (374 aa)
initn: 2453 init1: 2453 opt: 2453 Z-score: 2395.8 bits: 452.0 E(85289): 1e-126
Smith-Waterman score: 2453; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374)
10 20 30 40 50 60
pF1KE1 MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT
310 320 330 340 350 360
370
pF1KE1 SETADNDNASSFTM
::::::::::::::
NP_004 SETADNDNASSFTM
370
>>NP_001288647 (OMIM: 600242) C-C chemokine receptor typ (372 aa)
initn: 539 init1: 317 opt: 955 Z-score: 943.0 bits: 183.1 E(85289): 8.7e-46
Smith-Waterman score: 955; 42.1% identity (73.0% similar) in 366 aa overlap (13-373:20-371)
10 20 30 40 50
pF1KE1 MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEML--LCSLQEVRQFSRLFVPI
: : ... ::. :: .. ::: ..::.:. :.::
NP_001 MKSVLVVALLVIFQVCLCQDEVTDDYIGDNTT---VDYTLFESLCSKKDVRNFKAWFLPI
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 AYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAW
::.:: ::::: :::.:. ..:. ..:::.::::.:.:::::.::::::: : :. .:
NP_001 MYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYS-AAKSW
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 VFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVV
::. :::. .:: ..: ::::: :::.:::.:::::... : :.:.: ::. :. .
NP_001 VFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGI
120 130 140 150 160 170
180 190 200 210 220
pF1KE1 WGLSVIISSSTFVFN--QKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMF
: :....: .... :. ... . : . ..: .. . . ....::..::.
NP_001 WILATVLSIPELLYSDLQRSSSEQAMRC----SLITEHVEAFITIQVAQMVIGFLVPLLA
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 MIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLV-TAANLGKMNRSC
: ::: :..::.::.: .:.:::.::::::.::.. :.:.: :.:. :.::.. . .:
NP_001 MSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTC
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE1 QSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSC
. : .. . :: :: ..::.:: :::::: :::: ..:..::: :. .. . ::
NP_001 ELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSC
300 310 320 330 340 350
350 360 370
pF1KE1 AGRYSENISRQTSETADNDNASSFTM
:. :..: ... .....:.
NP_001 --RHI----RRSSMSVEAETTTTFSP
360 370
>>NP_001288646 (OMIM: 600242) C-C chemokine receptor typ (372 aa)
initn: 539 init1: 317 opt: 955 Z-score: 943.0 bits: 183.1 E(85289): 8.7e-46
Smith-Waterman score: 955; 42.1% identity (73.0% similar) in 366 aa overlap (13-373:20-371)
10 20 30 40 50
pF1KE1 MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEML--LCSLQEVRQFSRLFVPI
: : ... ::. :: .. ::: ..::.:. :.::
NP_001 MKSVLVVALLVIFQVCLCQDEVTDDYIGDNTT---VDYTLFESLCSKKDVRNFKAWFLPI
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 AYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAW
::.:: ::::: :::.:. ..:. ..:::.::::.:.:::::.::::::: : :. .:
NP_001 MYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYS-AAKSW
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 VFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVV
::. :::. .:: ..: ::::: :::.:::.:::::... : :.:.: ::. :. .
NP_001 VFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGI
120 130 140 150 160 170
180 190 200 210 220
pF1KE1 WGLSVIISSSTFVFN--QKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMF
: :....: .... :. ... . : . ..: .. . . ....::..::.
NP_001 WILATVLSIPELLYSDLQRSSSEQAMRC----SLITEHVEAFITIQVAQMVIGFLVPLLA
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 MIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLV-TAANLGKMNRSC
: ::: :..::.::.: .:.:::.::::::.::.. :.:.: :.:. :.::.. . .:
NP_001 MSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTC
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE1 QSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSC
. : .. . :: :: ..::.:: :::::: :::: ..:..::: :. .. . ::
NP_001 ELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSC
300 310 320 330 340 350
350 360 370
pF1KE1 AGRYSENISRQTSETADNDNASSFTM
:. :..: ... .....:.
NP_001 --RHI----RRSSMSVEAETTTTFSP
360 370
>>NP_001288645 (OMIM: 600242) C-C chemokine receptor typ (372 aa)
initn: 539 init1: 317 opt: 955 Z-score: 943.0 bits: 183.1 E(85289): 8.7e-46
Smith-Waterman score: 955; 42.1% identity (73.0% similar) in 366 aa overlap (13-373:20-371)
10 20 30 40 50
pF1KE1 MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEML--LCSLQEVRQFSRLFVPI
: : ... ::. :: .. ::: ..::.:. :.::
NP_001 MKSVLVVALLVIFQVCLCQDEVTDDYIGDNTT---VDYTLFESLCSKKDVRNFKAWFLPI
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 AYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAW
::.:: ::::: :::.:. ..:. ..:::.::::.:.:::::.::::::: : :. .:
NP_001 MYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYS-AAKSW
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 VFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVV
::. :::. .:: ..: ::::: :::.:::.:::::... : :.:.: ::. :. .
NP_001 VFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGI
120 130 140 150 160 170
180 190 200 210 220
pF1KE1 WGLSVIISSSTFVFN--QKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMF
: :....: .... :. ... . : . ..: .. . . ....::..::.
NP_001 WILATVLSIPELLYSDLQRSSSEQAMRC----SLITEHVEAFITIQVAQMVIGFLVPLLA
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 MIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLV-TAANLGKMNRSC
: ::: :..::.::.: .:.:::.::::::.::.. :.:.: :.:. :.::.. . .:
NP_001 MSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTC
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE1 QSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSC
. : .. . :: :: ..::.:: :::::: :::: ..:..::: :. .. . ::
NP_001 ELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSC
300 310 320 330 340 350
350 360 370
pF1KE1 AGRYSENISRQTSETADNDNASSFTM
:. :..: ... .....:.
NP_001 --RHI----RRSSMSVEAETTTTFSP
360 370
>>NP_001829 (OMIM: 600242) C-C chemokine receptor type 7 (378 aa)
initn: 539 init1: 317 opt: 955 Z-score: 942.9 bits: 183.2 E(85289): 8.8e-46
Smith-Waterman score: 955; 42.1% identity (73.0% similar) in 366 aa overlap (13-373:26-377)
10 20 30 40
pF1KE1 MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEML--LCSLQEVRQFS
: : ... ::. :: .. ::: ..::.:.
NP_001 MDLGKPMKSVLVVALLVIFQVCLCQDEVTDDYIGDNTT---VDYTLFESLCSKKDVRNFK
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 RLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVS
:.:: ::.:: ::::: :::.:. ..:. ..:::.::::.:.:::::.::::::: :
NP_001 AWFLPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 HATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSK
:. .:::. :::. .:: ..: ::::: :::.:::.:::::... : :.:.: ::
NP_001 -AAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISK
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 IICLVVWGLSVIISSSTFVFN--QKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGF
. :. .: :....: .... :. ... . : . ..: .. . . ....::
NP_001 LSCVGIWILATVLSIPELLYSDLQRSSSEQAMRC----SLITEHVEAFITIQVAQMVIGF
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 FIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLV-TAANLG
..::. : ::: :..::.::.: .:.:::.::::::.::.. :.:.: :.:. :.::..
NP_001 LVPLLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFN
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE1 KMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYK
. .:. : .. . :: :: ..::.:: :::::: :::: ..:..::: :. ..
NP_001 ITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQL
300 310 320 330 340 350
350 360 370
pF1KE1 SSGFSCAGRYSENISRQTSETADNDNASSFTM
. :: :. :..: ... .....:.
NP_001 RQWSSC--RHI----RRSSMSVEAETTTTFSP
360 370
>>NP_001288643 (OMIM: 600242) C-C chemokine receptor typ (315 aa)
initn: 476 init1: 254 opt: 881 Z-score: 872.0 bits: 169.8 E(85289): 7.8e-42
Smith-Waterman score: 881; 42.9% identity (74.4% similar) in 324 aa overlap (53-373:2-314)
30 40 50 60 70 80
pF1KE1 NTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTD
::.:: ::::: :::.:. ..:. ..:::
NP_001 MYSIICFVGLLGNGLVVLTYIYFKRLKTMTD
10 20 30
90 100 110 120 130 140
pF1KE1 VYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMD
.::::.:.:::::.::::::: : :. .:::. :::. .:: ..: ::::: :::.:
NP_001 TYLLNLAVADILFLLTLPFWAYS-AAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISID
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 RYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFN--QKYNTQGSDVCEPK
::.:::::... : :.:.: ::. :. .: :....: .... :. ... . :
NP_001 RYVAIVQAVSAHRHRARVLLISKLSCVGIWILATVLSIPELLYSDLQRSSSEQAMRC---
100 110 120 130 140
210 220 230 240 250 260
pF1KE1 YQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVV
. ..: .. . . ....::..::. : ::: :..::.::.: .:.:::.::::::
NP_001 -SLITEHVEAFITIQVAQMVIGFLVPLLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVV
150 160 170 180 190 200
270 280 290 300 310
pF1KE1 LVFLACQIPHNMVLLV-TAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFI
.::.. :.:.: :.:. :.::.. . .:. : .. . :: :: ..::.:: :::::
NP_001 VVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFI
210 220 230 240 250 260
320 330 340 350 360 370
pF1KE1 GQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
: :::: ..:..::: :. .. . :: :. :..: ... .....:.
NP_001 GVKFRNDLFKLFKDLGCLSQEQLRQWSSC--RHI----RRSSMSVEAETTTTFSP
270 280 290 300 310
>>NP_005499 (OMIM: 604836) C-C chemokine receptor type 4 (360 aa)
initn: 887 init1: 367 opt: 880 Z-score: 870.4 bits: 169.7 E(85289): 9.6e-42
Smith-Waterman score: 880; 41.5% identity (74.4% similar) in 328 aa overlap (6-332:1-320)
10 20 30 40 50 60
pF1KE1 MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
:: .:. :.. : :. ..:: .: :. . .. :..::.: :::. :::
NP_005 MNPTDIADTTLDE--SIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFG
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
:::: .::... ::. ::::::::::.::.:.:::..::::. .:. :::. . ::.
NP_005 LLGNSVVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGY-YAADQWVFGLGLCKM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
.. .: ..: :.... .:.:::.:::.:. : ::.::: . : :..:...:. :
NP_005 ISWMYLVGFYSGIFFVMLMSIDRYLAIVHAV--FSLRARTLTYGVITSLATWSVAVFASL
120 130 140 150 160 170
190 200 210 220 230
pF1KE1 STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLEL-LFGFFIPLMFMIFCYTFIVK
:.:. :. .. :. ::. : ::.: .::. ..:. ::: .:.:::..:..
NP_005 PGFLFSTCYTERNHTYCKTKYSLNSTT--WKVLS-SLEINILGLVIPLGIMLFCYSMIIR
180 190 200 210 220
240 250 260 270 280 290
pF1KE1 TLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKT
:: . .: :..::...:.:::..::. :.:.::.. . .. ..: :. . :.
NP_005 TLQHCKNEKKNKAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQ
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 VTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQ
.::.:::.::::::..: :.:.:::.:.:...:
NP_005 ATETLAFVHCCLNPIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSADTPSSSY
290 300 310 320 330 340
360 370
pF1KE1 TSETADNDNASSFTM
NP_005 TQSTMDHDLHDAL
350 360
>>XP_016861176 (OMIM: 604836) PREDICTED: C-C chemokine r (360 aa)
initn: 887 init1: 367 opt: 880 Z-score: 870.4 bits: 169.7 E(85289): 9.6e-42
Smith-Waterman score: 880; 41.5% identity (74.4% similar) in 328 aa overlap (6-332:1-320)
10 20 30 40 50 60
pF1KE1 MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
:: .:. :.. : :. ..:: .: :. . .. :..::.: :::. :::
XP_016 MNPTDIADTTLDE--SIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFG
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
:::: .::... ::. ::::::::::.::.:.:::..::::. .:. :::. . ::.
XP_016 LLGNSVVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGY-YAADQWVFGLGLCKM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
.. .: ..: :.... .:.:::.:::.:. : ::.::: . : :..:...:. :
XP_016 ISWMYLVGFYSGIFFVMLMSIDRYLAIVHAV--FSLRARTLTYGVITSLATWSVAVFASL
120 130 140 150 160 170
190 200 210 220 230
pF1KE1 STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLEL-LFGFFIPLMFMIFCYTFIVK
:.:. :. .. :. ::. : ::.: .::. ..:. ::: .:.:::..:..
XP_016 PGFLFSTCYTERNHTYCKTKYSLNSTT--WKVLS-SLEINILGLVIPLGIMLFCYSMIIR
180 190 200 210 220
240 250 260 270 280 290
pF1KE1 TLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKT
:: . .: :..::...:.:::..::. :.:.::.. . .. ..: :. . :.
XP_016 TLQHCKNEKKNKAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQ
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 VTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQ
.::.:::.::::::..: :.:.:::.:.:...:
XP_016 ATETLAFVHCCLNPIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSADTPSSSY
290 300 310 320 330 340
360 370
pF1KE1 TSETADNDNASSFTM
XP_016 TQSTMDHDLHDAL
350 360
>>NP_000625 (OMIM: 146929,609423) C-X-C chemokine recept (350 aa)
initn: 808 init1: 232 opt: 877 Z-score: 867.6 bits: 169.1 E(85289): 1.4e-41
Smith-Waterman score: 877; 42.5% identity (75.5% similar) in 327 aa overlap (9-331:2-320)
10 20 30 40 50
pF1KE1 MSGESMNFSDVFDSSEDYFVSVN-TSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVF
:.. : . : ..: :.. .: .. : : :.. ... : :::.:. ..
NP_000 MSNITDPQMWDFDDLNFTGMPPADEDYSPCML-ETETLNKYVVIIAYALVFLL
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 GLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCK
.:::: ::.... . . .::.:::::::.:.::.::.::::.::.:...: :.:.. ::
NP_000 SLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNG-WIFGTFLCK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 LLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIIS
... . .:: :.:::.:::.:::.:::.::... . . . :..:: ::::. .:
NP_000 VVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRHLV---KFVCLGCWGLSMNLS
120 130 140 150 160
180 190 200 210 220 230
pF1KE1 SSTFVFNQKYNTQGSD-VCEPKYQTV-SEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFI
:.: : :. ..:. :: :... .. .:.... : :::..::. :.::: :
NP_000 LPFFLFRQAYHPNNSSPVC---YEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFT
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 VKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLV-TAANLGKMNRSCQSEKLIGY
..:: .:. ...:.:.:::.::::.:: : .:.:.:::. : ...::. .. ::
NP_000 LRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQESCERRNNIGR
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 TKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENI
. .::.:.::: ::::..::::::.::. :::::
NP_000 ALDATEILGFLHSCLNPIIYAFIGQNFRHGFLKILAMHGLVSKEFLARHRVTSYTSSSVN
290 300 310 320 330 340
360 370
pF1KE1 SRQTSETADNDNASSFTM
NP_000 VSSNL
350
374 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:15:47 2016 done: Sun Nov 6 22:15:48 2016
Total Scan time: 7.090 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]