Result of FASTA (omim) for
pFN21AE1388
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1388, 517 aa
1>>>pF1KE1388 517 - 517 aa - 517 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4752+/-0.000434; mu= 17.1456+/- 0.027
mean_var=65.3413+/-13.346, 0's: 0 Z-trim(109.8): 21 B-trim: 20 in 1/52
Lambda= 0.158665
statistics sampled from 18061 (18080) to 18061 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.577), E-opt: 0.2 (0.212), width: 16
Scan time: 6.910
The best scores are: opt bits E(85289)
NP_002694 (OMIM: 172450) amidophosphoribosyltransf ( 517) 3445 797.9 0
XP_011532689 (OMIM: 172450) PREDICTED: amidophosph ( 436) 2842 659.9 4.4e-189
XP_006715005 (OMIM: 603865) PREDICTED: glutamine-- ( 628) 200 55.2 6.9e-07
NP_005101 (OMIM: 603865) glutamine--fructose-6-pho ( 682) 200 55.2 7.4e-07
XP_016859291 (OMIM: 138292,608931,610542) PREDICTE ( 706) 157 45.3 0.0007
XP_016859290 (OMIM: 138292,608931,610542) PREDICTE ( 724) 148 43.3 0.003
>>NP_002694 (OMIM: 172450) amidophosphoribosyltransferas (517 aa)
initn: 3445 init1: 3445 opt: 3445 Z-score: 4260.4 bits: 797.9 E(85289): 0
Smith-Waterman score: 3445; 100.0% identity (100.0% similar) in 517 aa overlap (1-517:1-517)
10 20 30 40 50 60
pF1KE1 MELEELGIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MELEELGIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FKSHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FKSHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 HNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PTAYSLLIMHRDVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PTAYSLLIMHRDVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SIGARYYREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SIGARYYREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TVRYRCGQQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TVRYRCGQQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 NMRLRQLGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NMRLRQLGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 PIKYPCFMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKKQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PIKYPCFMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKKQKE
430 440 450 460 470 480
490 500 510
pF1KE1 KKHDIMIQENGNGLECFEKSGHCTACLTGKYPVELEW
:::::::::::::::::::::::::::::::::::::
NP_002 KKHDIMIQENGNGLECFEKSGHCTACLTGKYPVELEW
490 500 510
>>XP_011532689 (OMIM: 172450) PREDICTED: amidophosphorib (436 aa)
initn: 2842 init1: 2842 opt: 2842 Z-score: 3515.6 bits: 659.9 E(85289): 4.4e-189
Smith-Waterman score: 2842; 100.0% identity (100.0% similar) in 427 aa overlap (91-517:10-436)
70 80 90 100 110 120
pF1KE1 FKSHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVA
::::::::::::::::::::::::::::::
XP_011 MGVRCQHSNHTRYATTGKCELENCQPFVVETLHGKIAVA
10 20 30
130 140 150 160 170 180
pF1KE1 HNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEA
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE1 PTAYSLLIMHRDVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTAYSLLIMHRDVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFL
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE1 SIGARYYREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIGARYYREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVY
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE1 TVRYRCGQQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVRYRCGQQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQP
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE1 NMRLRQLGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMRLRQLGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASP
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE1 PIKYPCFMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKKQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIKYPCFMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKKQKE
340 350 360 370 380 390
490 500 510
pF1KE1 KKHDIMIQENGNGLECFEKSGHCTACLTGKYPVELEW
:::::::::::::::::::::::::::::::::::::
XP_011 KKHDIMIQENGNGLECFEKSGHCTACLTGKYPVELEW
400 410 420 430
>>XP_006715005 (OMIM: 603865) PREDICTED: glutamine--fruc (628 aa)
initn: 207 init1: 99 opt: 200 Z-score: 244.7 bits: 55.2 E(85289): 6.9e-07
Smith-Waterman score: 209; 27.0% identity (58.3% similar) in 211 aa overlap (12-209:2-207)
10 20 30 40 50 60
pF1KE1 MELEELGIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPT
::.:. . :. .. ... :: :..:: .:::.. ::.. .
XP_006 MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAI-DGNNHEV
10 20 30 40
70 80 90 100 110
pF1KE1 FKSH----KGMGLVN----HVFTED--NLKKLYVSNLGIGHTRYATTGKCELENCQPFVV
. : : : :. ... .: .:: . ...::.:::.:: : : .:
XP_006 KERHIQLVKKRGKVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPSAVNSHPQRS
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 ETLHGKIAVAHNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWV
. ....: ::: ..: ::: : .: . . .:.: :..:. :. ... . .
XP_006 DK-GNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFS
110 120 130 140 150 160
180 190 200 210 220
pF1KE1 ARIKNLMKEAPTAYSLLIMHRDVIY---AVRDPYGNRPLCIGRLIPVSDINDKEKKTSET
. .. .... :..:.. ..: : :: :. :: ::
XP_006 TLVERVIQQLEGAFALVF--KSVHYPGEAVATRRGS-PLLIGVRSKYKLSTEQIPILYRT
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 EGWVVSSESCSFLSIGARYYREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYF
XP_006 CTLENVKNICKTRMKRLDSSACLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAV
230 240 250 260 270 280
>>NP_005101 (OMIM: 603865) glutamine--fructose-6-phospha (682 aa)
initn: 207 init1: 99 opt: 200 Z-score: 244.1 bits: 55.2 E(85289): 7.4e-07
Smith-Waterman score: 209; 27.0% identity (58.3% similar) in 211 aa overlap (12-209:2-207)
10 20 30 40 50 60
pF1KE1 MELEELGIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPT
::.:. . :. .. ... :: :..:: .:::.. ::.. .
NP_005 MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAI-DGNNHEV
10 20 30 40
70 80 90 100 110
pF1KE1 FKSH----KGMGLVN----HVFTED--NLKKLYVSNLGIGHTRYATTGKCELENCQPFVV
. : : : :. ... .: .:: . ...::.:::.:: : : .:
NP_005 KERHIQLVKKRGKVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPSAVNSHPQRS
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 ETLHGKIAVAHNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWV
. ....: ::: ..: ::: : .: . . .:.: :..:. :. ... . .
NP_005 DK-GNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFS
110 120 130 140 150 160
180 190 200 210 220
pF1KE1 ARIKNLMKEAPTAYSLLIMHRDVIY---AVRDPYGNRPLCIGRLIPVSDINDKEKKTSET
. .. .... :..:.. ..: : :: :. :: ::
NP_005 TLVERVIQQLEGAFALVF--KSVHYPGEAVATRRGS-PLLIGVRSKYKLSTEQIPILYRT
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 EGWVVSSESCSFLSIGARYYREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYF
NP_005 CTLENVKNICKTRMKRLDSSACLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAV
230 240 250 260 270 280
>>XP_016859291 (OMIM: 138292,608931,610542) PREDICTED: g (706 aa)
initn: 105 init1: 65 opt: 157 Z-score: 190.7 bits: 45.3 E(85289): 0.0007
Smith-Waterman score: 181; 25.8% identity (55.2% similar) in 252 aa overlap (13-239:28-273)
10 20 30 40
pF1KE1 MELEELGIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQ
:.:. . :. .. ... :: :..::
XP_016 MTKIRELPSRNCCLIRGKKMNAHATASGIFAYLNYHVPRTRREILETLIKGLQRLEYRGY
10 20 30 40 50 60
50 60 70 80 90
pF1KE1 ESAGIVTSDGSSVPTFKSH-------KGMGLVN------HVFTEDNLKKLYVSNLGIGHT
.::: : ::.. .... : : :. : . .: . .:::.::
XP_016 DSAG-VGFDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHT
70 80 90 100 110
100 110 120 130 140 150
pF1KE1 RYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAARLRKKLLRHGIGLSTSSDSEMIT
:.:: :. : .: . .... : ::: ..: :.: : .: . . .:.: :.
XP_016 RWATHGEPSPVNSHPQRSDK-NNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIA
120 130 140 150 160 170
160 170 180 190 200
pF1KE1 QLLAYTPPQEQDDTPDWVARIKNLMKEAPTAYSLLIMHRDVIY---AVRDPYGNRPLCIG
.:. : ..... .... .. .... :..:.. ..: . :: :. :: ::
XP_016 KLVKYMYDNRESQDTSFTTLVERVIQQLEGAFALVF--KSVHFPGQAVGTRRGS-PLLIG
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE1 -----RL----IPVSDINDKEKKTSETEGWVVSSESCSFLSIGARYYREVLPGEIVEISR
.: ::. . :.:: : . . : .: .: :
XP_016 VRSEHKLSTDHIPILYRTGKDKKGSCNLSRV-DSTTCLFPVEEKAVEYYFASDASAVIEH
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE1 HNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVYTVRYRCGQQLAIEAPVDADL
XP_016 TNRVIFLEDDDVAAVVDGRLSIHRIKRTAGDHPGRAVQTLQMELQQIMKGNFSSFMQKEI
300 310 320 330 340 350
>>XP_016859290 (OMIM: 138292,608931,610542) PREDICTED: g (724 aa)
initn: 105 init1: 65 opt: 148 Z-score: 179.4 bits: 43.3 E(85289): 0.003
Smith-Waterman score: 172; 25.4% identity (56.3% similar) in 213 aa overlap (13-209:28-235)
10 20 30 40
pF1KE1 MELEELGIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQ
:.:. . :. .. ... :: :..::
XP_016 MTKIRELPSRNCCLIRGKKMNAHATASGIFAYLNYHVPRTRREILETLIKGLQRLEYRGY
10 20 30 40 50 60
50 60 70 80 90
pF1KE1 ESAGIVTSDGSSVPTFKSH-------KGMGLVN------HVFTEDNLKKLYVSNLGIGHT
.::: : ::.. .... : : :. : . .: . .:::.::
XP_016 DSAG-VGFDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHT
70 80 90 100 110
100 110 120 130 140 150
pF1KE1 RYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAARLRKKLLRHGIGLSTSSDSEMIT
:.:: :. : .: . .... : ::: ..: :.: : .: . . .:.: :.
XP_016 RWATHGEPSPVNSHPQRSDK-NNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIA
120 130 140 150 160 170
160 170 180 190 200
pF1KE1 QLLAYTPPQEQDDTPDWVARIKNLMKEAPTAYSLLIMHRDVIY---AVRDPYGNRPLCIG
.:. : ..... .... .. .... :..:.. ..: . :: :. :: ::
XP_016 KLVKYMYDNRESQDTSFTTLVERVIQQLEGAFALVF--KSVHFPGQAVGTRRGS-PLLIG
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE1 RLIPVSDINDKEKKTSETEGWVVSSESCSFLSIGARYYREVLPGEIVEISRHNVQTLDII
XP_016 VRSEHKLSTDHIPILYRTARTQIGSKFTRWGSQGERGKDKKGSCNLSRVDSTTCLFPVEE
240 250 260 270 280 290
517 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:30:29 2016 done: Mon Nov 7 02:30:30 2016
Total Scan time: 6.910 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]