Result of FASTA (omim) for
pFN21AE1377
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1377, 526 aa
1>>>pF1KE1377 526 - 526 aa - 526 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.0027+/-0.000397; mu= 2.6172+/- 0.025
mean_var=260.5869+/-55.775, 0's: 0 Z-trim(120.3): 87 B-trim: 0 in 0/54
Lambda= 0.079451
statistics sampled from 35198 (35359) to 35198 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.415), width: 16
Scan time: 7.240
The best scores are: opt bits E(85289)
XP_011507882 (OMIM: 233710,608515) PREDICTED: neut ( 526) 3521 417.0 7e-116
NP_000424 (OMIM: 233710,608515) neutrophil cytosol ( 526) 3521 417.0 7e-116
NP_001121123 (OMIM: 233710,608515) neutrophil cyto ( 526) 3521 417.0 7e-116
XP_011507883 (OMIM: 233710,608515) PREDICTED: neut ( 526) 3521 417.0 7e-116
NP_001177723 (OMIM: 233710,608515) neutrophil cyto ( 481) 2417 290.4 8.1e-78
NP_001177718 (OMIM: 233710,608515) neutrophil cyto ( 445) 2186 263.9 7.2e-70
XP_005245264 (OMIM: 233710,608515) PREDICTED: neut ( 490) 2186 264.0 7.7e-70
NP_001242996 (OMIM: 611255) NADPH oxidase activato ( 476) 526 73.7 1.4e-12
NP_006638 (OMIM: 611255) NADPH oxidase activator 1 ( 483) 526 73.7 1.4e-12
XP_011516460 (OMIM: 611255) PREDICTED: NADPH oxida ( 447) 389 57.9 7.3e-08
NP_001242997 (OMIM: 611255) NADPH oxidase activato ( 427) 386 57.6 8.9e-08
>>XP_011507882 (OMIM: 233710,608515) PREDICTED: neutroph (526 aa)
initn: 3521 init1: 3521 opt: 3521 Z-score: 2201.5 bits: 417.0 E(85289): 7e-116
Smith-Waterman score: 3521; 99.6% identity (100.0% similar) in 526 aa overlap (1-526:1-526)
10 20 30 40 50 60
pF1KE1 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 TVVMKTQPGLPYSQVRDMVSKKLELRLEQTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_011 TVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
430 440 450 460 470 480
490 500 510 520
pF1KE1 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
490 500 510 520
>>NP_000424 (OMIM: 233710,608515) neutrophil cytosol fac (526 aa)
initn: 3521 init1: 3521 opt: 3521 Z-score: 2201.5 bits: 417.0 E(85289): 7e-116
Smith-Waterman score: 3521; 99.6% identity (100.0% similar) in 526 aa overlap (1-526:1-526)
10 20 30 40 50 60
pF1KE1 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 TVVMKTQPGLPYSQVRDMVSKKLELRLEQTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_000 TVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
430 440 450 460 470 480
490 500 510 520
pF1KE1 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
490 500 510 520
>>NP_001121123 (OMIM: 233710,608515) neutrophil cytosol (526 aa)
initn: 3521 init1: 3521 opt: 3521 Z-score: 2201.5 bits: 417.0 E(85289): 7e-116
Smith-Waterman score: 3521; 99.6% identity (100.0% similar) in 526 aa overlap (1-526:1-526)
10 20 30 40 50 60
pF1KE1 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 TVVMKTQPGLPYSQVRDMVSKKLELRLEQTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_001 TVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
430 440 450 460 470 480
490 500 510 520
pF1KE1 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
490 500 510 520
>>XP_011507883 (OMIM: 233710,608515) PREDICTED: neutroph (526 aa)
initn: 3521 init1: 3521 opt: 3521 Z-score: 2201.5 bits: 417.0 E(85289): 7e-116
Smith-Waterman score: 3521; 99.6% identity (100.0% similar) in 526 aa overlap (1-526:1-526)
10 20 30 40 50 60
pF1KE1 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 TVVMKTQPGLPYSQVRDMVSKKLELRLEQTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_011 TVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
430 440 450 460 470 480
490 500 510 520
pF1KE1 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
490 500 510 520
>>NP_001177723 (OMIM: 233710,608515) neutrophil cytosol (481 aa)
initn: 3207 init1: 2416 opt: 2417 Z-score: 1518.1 bits: 290.4 E(85289): 8.1e-78
Smith-Waterman score: 3121; 91.1% identity (91.4% similar) in 526 aa overlap (1-526:1-481)
10 20 30 40 50 60
pF1KE1 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG
:: :::::::::::::
NP_001 CE---------------------------------------------KQKLYEPVVIPVG
130
190 200 210 220 230 240
pF1KE1 RLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE1 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE1 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE1 TVVMKTQPGLPYSQVRDMVSKKLELRLEQTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_001 TVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE1 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
380 390 400 410 420 430
490 500 510 520
pF1KE1 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
440 450 460 470 480
>>NP_001177718 (OMIM: 233710,608515) neutrophil cytosol (445 aa)
initn: 2186 init1: 2186 opt: 2186 Z-score: 1375.4 bits: 263.9 E(85289): 7.2e-70
Smith-Waterman score: 2819; 84.4% identity (84.6% similar) in 526 aa overlap (1-526:1-445)
10 20 30 40 50 60
pF1KE1 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG
:::
NP_001 CEV---------------------------------------------------------
190 200 210 220 230 240
pF1KE1 RLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
::::::::::::::::::::::::::::::::::::
NP_001 ------------------------VASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
130 140 150
250 260 270 280 290 300
pF1KE1 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE1 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE1 TVVMKTQPGLPYSQVRDMVSKKLELRLEQTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_001 TVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE1 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
340 350 360 370 380 390
490 500 510 520
pF1KE1 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
400 410 420 430 440
>>XP_005245264 (OMIM: 233710,608515) PREDICTED: neutroph (490 aa)
initn: 3277 init1: 2186 opt: 2186 Z-score: 1374.9 bits: 264.0 E(85289): 7.7e-70
Smith-Waterman score: 3209; 93.0% identity (93.2% similar) in 526 aa overlap (1-526:1-490)
10 20 30 40 50 60
pF1KE1 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVW-------------
130 140 150 160
190 200 210 220 230 240
pF1KE1 RLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
:::::::::::::::::::::::::::::::::::::
XP_005 -----------------------VVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
170 180 190 200
250 260 270 280 290 300
pF1KE1 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE1 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE1 TVVMKTQPGLPYSQVRDMVSKKLELRLEQTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_005 TVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE1 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
390 400 410 420 430 440
490 500 510 520
pF1KE1 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
450 460 470 480 490
>>NP_001242996 (OMIM: 611255) NADPH oxidase activator 1 (476 aa)
initn: 717 init1: 526 opt: 526 Z-score: 346.7 bits: 73.7 E(85289): 1.4e-12
Smith-Waterman score: 722; 31.9% identity (53.9% similar) in 521 aa overlap (2-511:3-453)
10 20 30 40 50
pF1KE1 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKA
:: . . :. :. :.:. :: :: ::.: : .:.::: ::.. . . : .:
NP_001 MASLGDLVRAWHLGAQAVDRGDWARALHLFSGVPAPPARLCFNAGCVHLLAGDPEAALRA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 FTRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLF
: .....: .::..::::. .: ... :..:. :: ::::. ::: :::.:::
NP_001 FDQAVTKDTCMAVGFFQRGVANFQLARFQEALSDFWLALEQLRGHAAIDYTQLGLRFKLQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 ACEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPV
: :::.:.: . : .: .: : : : . .:.:.. : .. : .:
NP_001 AWEVLHNVASAQCQLGLWTEAASSLREAMSKWPEGSLNGLDSALDQVQRRGSLPPRQVPR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 GRLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRA
:..:::.. .. .: :.:::: ::::.. .:. : : :::. : . . :.
NP_001 GEVFRPHRWHLKHLEPVDFLGKAKVVASAIPDDQGWGVRPQQPQG------PGANHDARS
190 200 210 220 230
240 250 260 270 280 290
pF1KE1 LEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVEL
: .. :. : : .: : : ... ..
NP_001 LIMDSPRAGTHQGP-LDAETEV-----------GADRCTSTAYQ----------------
240 250 260
300 310 320 330 340 350
pF1KE1 RIHPQQQPQEESSPQSDIPAPPSSKAPGRPQLS-PGQKQKEEPKEVKL-----SVPMPYT
.:.:: : : :: : :: : .. :: :.: . : :. :
NP_001 ----EQRPQVE---QVGKQAPLS---PGLPAMGGPGPGPCEDPAGAGGAGAGGSEPL-VT
270 280 290 300 310
360 370 380 390 400 410
pF1KE1 LKVHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEQTKLSY-RPRDSNELVPLSED-SMK
. :. .::..... : :..: .... : . . .::: : .... ::. :. :..
NP_001 VTVQCAFTVALRARRGADLSSLRALLGQALPHQAQLGQLSYLAPGEDGHWVPIPEEESLQ
320 330 340 350 360 370
420 430 440 450 460
pF1KE1 DAWGQVKNYC---LTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSY
:: : : : : :... : .: : :: : ::
NP_001 RAW-QDAAACPRGLQLQCRGAGG---------------------RPVL---YQVVAQHSY
380 390 400 410
470 480 490 500 510 520
pF1KE1 EATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
: :::: :..:: . :: .:.. ::::.: :..::::: ::
NP_001 SAQGPEDLGFRQGDTVDVLCEVDQAWLEGHCDGRIGIFPKCFVVPAGPRMSGAPGRLPRS
420 430 440 450 460 470
NP_001 QQGDQP
>>NP_006638 (OMIM: 611255) NADPH oxidase activator 1 iso (483 aa)
initn: 703 init1: 526 opt: 526 Z-score: 346.6 bits: 73.7 E(85289): 1.4e-12
Smith-Waterman score: 698; 31.4% identity (53.2% similar) in 528 aa overlap (2-511:3-460)
10 20 30 40 50
pF1KE1 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKA
:: . . :. :. :.:. :: :: ::.: : .:.::: ::.. . . : .:
NP_006 MASLGDLVRAWHLGAQAVDRGDWARALHLFSGVPAPPARLCFNAGCVHLLAGDPEAALRA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 FTRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLF
: .....: .::..::::. .: ... :..:. :: ::::. ::: :::.:::
NP_006 FDQAVTKDTCMAVGFFQRGVANFQLARFQEALSDFWLALEQLRGHAAIDYTQLGLRFKLQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 ACEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPV
: :::.:.: . : .: .: : : : . .:.:.. : .. : .:
NP_006 AWEVLHNVASAQCQLGLWTEAASSLREAMSKWPEGSLNGLDSALDQVQRRGSLPPRQVPR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 GRLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRA
:..:::.. .. .: :.:::: ::::.. .:. : : :::. : . . :.
NP_006 GEVFRPHRWHLKHLEPVDFLGKAKVVASAIPDDQGWGVRPQQPQG------PGANHDARS
190 200 210 220 230
240 250 260 270 280 290
pF1KE1 LEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVEL
: .. :. : : .: : : ... ..
NP_006 LIMDSPRAGTHQGP-LDAETEV-----------GADRCTSTAYQ----------------
240 250 260
300 310 320 330 340 350
pF1KE1 RIHPQQQPQEESSPQSDIPAPPSSKAPGRPQLS-PGQKQKEEPKEVKL-----SVPMPYT
.:.:: : : :: : :: : .. :: :.: . : :. :
NP_006 ----EQRPQVE---QVGKQAPLS---PGLPAMGGPGPGPCEDPAGAGGAGAGGSEPL-VT
270 280 290 300 310
360 370 380 390 400 410
pF1KE1 LKVHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEQTKLSY-RPRDSNELVPLSED-SMK
. :. .::..... : :..: .... : . . .::: : .... ::. :. :..
NP_006 VTVQCAFTVALRARRGADLSSLRALLGQALPHQAQLGQLSYLAPGEDGHWVPIPEEESLQ
320 330 340 350 360 370
420 430 440 450 460
pF1KE1 DAWGQVKNYC---LTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSY
:: : : : : :... : .: : :: : ::
NP_006 RAW-QDAAACPRGLQLQCRGAGG---------------------RPVL---YQVVAQHSY
380 390 400 410
470 480 490 500 510 520
pF1KE1 EATQPEDLEFQEGDIILVLSK-------VNEEWLEGECKGKVGIFPKVFVEDCATTDLES
: :::: :..:: . :: . :.. ::::.: :..::::: ::
NP_006 SAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGPRMSGA
420 430 440 450 460 470
pF1KE1 TRREV
NP_006 PGRLPRSQQGDQP
480
>>XP_011516460 (OMIM: 611255) PREDICTED: NADPH oxidase a (447 aa)
initn: 585 init1: 357 opt: 389 Z-score: 262.2 bits: 57.9 E(85289): 7.3e-08
Smith-Waterman score: 536; 30.3% identity (50.4% similar) in 528 aa overlap (2-511:3-424)
10 20 30 40 50
pF1KE1 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKA
:: . . :. :. :.:. :: :: ::.: : .:.::: ::.. . . : .:
XP_011 MASLGDLVRAWHLGAQAVDRGDWARALHLFSGVPAPPARLCFNAGCVHLLAGDPEAALRA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 FTRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLF
: .....: .::..::::. .: ... :..:. :: ::::. ::: :::.:::
XP_011 FDQAVTKDTCMAVGFFQRGVANFQLARFQEALSDFWLALEQLRGHAAIDYTQLGLRFKLQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 ACEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPV
: :::.:.: .:. ::.: : : :.. ..: : :
XP_011 AWEVLHNVA----------SAQCQLGLWTEAASSLREA-MSK-----W----------PE
130 140 150
180 190 200 210 220 230
pF1KE1 GRLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRA
: : : . : : .. ::::.. .:. : : :::. : . . :.
XP_011 GSL---NGLDSA-------LDQVQVVASAIPDDQGWGVRPQQPQG------PGANHDARS
160 170 180 190
240 250 260 270 280 290
pF1KE1 LEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVEL
: .. :. : : .: : : ... ..
XP_011 LIMDSPRAGTHQGP-LDAETEV-----------GADRCTSTAYQ----------------
200 210 220 230
300 310 320 330 340 350
pF1KE1 RIHPQQQPQEESSPQSDIPAPPSSKAPGRPQLS-PGQKQKEEPKEVKL-----SVPMPYT
.:.:: : : :: : :: : .. :: :.: . : :. :
XP_011 ----EQRPQVE---QVGKQAPLS---PGLPAMGGPGPGPCEDPAGAGGAGAGGSEPL-VT
240 250 260 270
360 370 380 390 400 410
pF1KE1 LKVHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEQTKLSY-RPRDSNELVPLSED-SMK
. :. .::..... : :..: .... : . . .::: : .... ::. :. :..
XP_011 VTVQCAFTVALRARRGADLSSLRALLGQALPHQAQLGQLSYLAPGEDGHWVPIPEEESLQ
280 290 300 310 320 330
420 430 440 450 460
pF1KE1 DAWGQVKNYC---LTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSY
:: : : : : :... : .: : :: : ::
XP_011 RAW-QDAAACPRGLQLQCRGAGG---------------------RPVL---YQVVAQHSY
340 350 360 370
470 480 490 500 510 520
pF1KE1 EATQPEDLEFQEGDIILVLSK-------VNEEWLEGECKGKVGIFPKVFVEDCATTDLES
: :::: :..:: . :: . :.. ::::.: :..::::: ::
XP_011 SAQGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFVVPAGPRMSGA
380 390 400 410 420 430
pF1KE1 TRREV
XP_011 PGRLPRSQQGDQP
440
526 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:49:35 2016 done: Mon Nov 7 02:49:36 2016
Total Scan time: 7.240 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]