Result of FASTA (omim) for
pFN21AE1364
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1364, 303 aa
1>>>pF1KE1364 303 - 303 aa - 303 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2234+/-0.000376; mu= 16.1965+/- 0.023
mean_var=63.9414+/-12.737, 0's: 0 Z-trim(112.2): 86 B-trim: 276 in 2/53
Lambda= 0.160392
statistics sampled from 20926 (21017) to 20926 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.246), width: 16
Scan time: 7.140
The best scores are: opt bits E(85289)
NP_001253985 (OMIM: 601761) caspase-7 isoform alph ( 303) 2063 486.1 3.8e-137
NP_001218 (OMIM: 601761) caspase-7 isoform alpha p ( 303) 2063 486.1 3.8e-137
NP_203125 (OMIM: 601761) caspase-7 isoform alpha p ( 303) 2063 486.1 3.8e-137
XP_016872252 (OMIM: 601761) PREDICTED: caspase-7 i ( 322) 2063 486.1 4e-137
NP_203124 (OMIM: 601761) caspase-7 isoform delta [ ( 336) 2063 486.1 4.1e-137
NP_001307840 (OMIM: 601761) caspase-7 isoform g [H ( 311) 1830 432.1 6.5e-121
XP_016872253 (OMIM: 601761) PREDICTED: caspase-7 i ( 311) 1830 432.1 6.5e-121
XP_006718080 (OMIM: 601761) PREDICTED: caspase-7 i ( 317) 1830 432.2 6.6e-121
NP_001253987 (OMIM: 601761) caspase-7 isoform f [H ( 278) 1829 431.9 7e-121
NP_001253986 (OMIM: 601761) caspase-7 isoform e [H ( 388) 1830 432.2 7.9e-121
XP_011538562 (OMIM: 601761) PREDICTED: caspase-7 i ( 270) 1826 431.2 1.1e-120
NP_203126 (OMIM: 601761) caspase-7 isoform beta [H ( 253) 995 238.9 8e-63
XP_011530603 (OMIM: 600636) PREDICTED: caspase-3 i ( 277) 942 226.6 4.3e-59
NP_004337 (OMIM: 600636) caspase-3 preproprotein [ ( 277) 942 226.6 4.3e-59
NP_116786 (OMIM: 600636) caspase-3 preproprotein [ ( 277) 942 226.6 4.3e-59
XP_005246964 (OMIM: 601762,603909,605027,613659) P ( 521) 582 143.5 8.6e-34
NP_116759 (OMIM: 601762,603909,605027,613659) casp ( 522) 582 143.5 8.6e-34
NP_001221 (OMIM: 601762,603909,605027,613659) casp ( 479) 576 142.1 2.1e-33
XP_005246951 (OMIM: 114480,114550,211980,601763,60 ( 280) 572 141.0 2.5e-33
XP_006712859 (OMIM: 601762,603909,605027,613659) P ( 272) 564 139.2 9e-33
XP_011510271 (OMIM: 114480,114550,211980,601763,60 ( 334) 565 139.4 9.1e-33
NP_203520 (OMIM: 114480,114550,211980,601763,60727 ( 464) 565 139.5 1.2e-32
NP_001073593 (OMIM: 114480,114550,211980,601763,60 ( 464) 565 139.5 1.2e-32
XP_005246949 (OMIM: 114480,114550,211980,601763,60 ( 464) 565 139.5 1.2e-32
XP_005246943 (OMIM: 114480,114550,211980,601763,60 ( 479) 565 139.5 1.2e-32
XP_005246944 (OMIM: 114480,114550,211980,601763,60 ( 479) 565 139.5 1.2e-32
XP_006712853 (OMIM: 114480,114550,211980,601763,60 ( 479) 565 139.5 1.2e-32
NP_203519 (OMIM: 114480,114550,211980,601763,60727 ( 479) 565 139.5 1.2e-32
XP_005246948 (OMIM: 114480,114550,211980,601763,60 ( 479) 565 139.5 1.2e-32
XP_005246947 (OMIM: 114480,114550,211980,601763,60 ( 479) 565 139.5 1.2e-32
XP_005246945 (OMIM: 114480,114550,211980,601763,60 ( 479) 565 139.5 1.2e-32
XP_005246946 (OMIM: 114480,114550,211980,601763,60 ( 479) 565 139.5 1.2e-32
XP_006712852 (OMIM: 114480,114550,211980,601763,60 ( 479) 565 139.5 1.2e-32
NP_001219 (OMIM: 114480,114550,211980,601763,60727 ( 496) 565 139.5 1.3e-32
XP_005246942 (OMIM: 114480,114550,211980,601763,60 ( 523) 565 139.6 1.3e-32
NP_001073594 (OMIM: 114480,114550,211980,601763,60 ( 538) 565 139.6 1.4e-32
NP_116756 (OMIM: 601762,603909,605027,613659) casp ( 521) 517 128.4 2.9e-29
NP_001193471 (OMIM: 601762,603909,605027,613659) c ( 478) 511 127.0 7.1e-29
NP_001193453 (OMIM: 601762,603909,605027,613659) c ( 455) 479 119.6 1.2e-26
NP_001217 (OMIM: 601532) caspase-6 isoform alpha p ( 293) 351 89.9 6.6e-18
NP_036246 (OMIM: 605848) caspase-14 precursor [Hom ( 242) 345 88.5 1.5e-17
XP_005246071 (OMIM: 602234) PREDICTED: caspase-9 i ( 333) 320 82.8 1.1e-15
NP_127463 (OMIM: 602234) caspase-9 isoform 3 [Homo ( 333) 320 82.8 1.1e-15
NP_001220 (OMIM: 602234) caspase-9 isoform alpha p ( 416) 320 82.8 1.3e-15
XP_011540575 (OMIM: 602234) PREDICTED: caspase-9 i ( 421) 320 82.8 1.3e-15
NP_116787 (OMIM: 601532) caspase-6 isoform beta [H ( 204) 293 76.4 5.3e-14
XP_011526163 (OMIM: 605848) PREDICTED: caspase-14 ( 230) 260 68.8 1.2e-11
NP_001215 (OMIM: 600639) caspase-2 isoform 2 [Homo ( 312) 254 67.5 4e-11
NP_116764 (OMIM: 600639) caspase-2 isoform 1 prepr ( 452) 203 55.8 1.9e-07
NP_001189444 (OMIM: 603599) CASP8 and FADD-like ap ( 235) 199 54.7 2.1e-07
>>NP_001253985 (OMIM: 601761) caspase-7 isoform alpha pr (303 aa)
initn: 2063 init1: 2063 opt: 2063 Z-score: 2583.3 bits: 486.1 E(85289): 3.8e-137
Smith-Waterman score: 2063; 99.7% identity (100.0% similar) in 303 aa overlap (1-303:1-303)
10 20 30 40 50 60
pF1KE1 MADEQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
250 260 270 280 290 300
pF1KE1 FSQ
:::
NP_001 FSQ
>>NP_001218 (OMIM: 601761) caspase-7 isoform alpha precu (303 aa)
initn: 2063 init1: 2063 opt: 2063 Z-score: 2583.3 bits: 486.1 E(85289): 3.8e-137
Smith-Waterman score: 2063; 99.7% identity (100.0% similar) in 303 aa overlap (1-303:1-303)
10 20 30 40 50 60
pF1KE1 MADEQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
250 260 270 280 290 300
pF1KE1 FSQ
:::
NP_001 FSQ
>>NP_203125 (OMIM: 601761) caspase-7 isoform alpha precu (303 aa)
initn: 2063 init1: 2063 opt: 2063 Z-score: 2583.3 bits: 486.1 E(85289): 3.8e-137
Smith-Waterman score: 2063; 99.7% identity (100.0% similar) in 303 aa overlap (1-303:1-303)
10 20 30 40 50 60
pF1KE1 MADEQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_203 MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_203 NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_203 DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_203 FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_203 FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
250 260 270 280 290 300
pF1KE1 FSQ
:::
NP_203 FSQ
>>XP_016872252 (OMIM: 601761) PREDICTED: caspase-7 isofo (322 aa)
initn: 2063 init1: 2063 opt: 2063 Z-score: 2582.9 bits: 486.1 E(85289): 4e-137
Smith-Waterman score: 2063; 99.7% identity (100.0% similar) in 303 aa overlap (1-303:20-322)
10 20 30 40
pF1KE1 MADEQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKK
:::.:::::::::::::::::::::::::::::::::::::
XP_016 MGTTVIPADCWRGWTELIMMADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 NVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCF
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 RSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKD
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE1 LTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLF
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE1 AYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPH
250 260 270 280 290 300
290 300
pF1KE1 FHEKKQIPCVVSMLTKELYFSQ
::::::::::::::::::::::
XP_016 FHEKKQIPCVVSMLTKELYFSQ
310 320
>>NP_203124 (OMIM: 601761) caspase-7 isoform delta [Homo (336 aa)
initn: 2063 init1: 2063 opt: 2063 Z-score: 2582.6 bits: 486.1 E(85289): 4.1e-137
Smith-Waterman score: 2063; 99.7% identity (100.0% similar) in 303 aa overlap (1-303:34-336)
10 20 30
pF1KE1 MADEQGCIEEQGVEDSANEDSVDAKPDRSS
:::.::::::::::::::::::::::::::
NP_203 VGWPPGRKWHLEKNTSCGGSSGICASYVTQMADDQGCIEEQGVEDSANEDSVDAKPDRSS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE1 FVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_203 FVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGT
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 DKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_203 DKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVI
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE1 YGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_203 YGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPR
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE1 YKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_203 YKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVA
250 260 270 280 290 300
280 290 300
pF1KE1 RHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
:::::::::::::::::::::::::::::::::
NP_203 RHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
310 320 330
>>NP_001307840 (OMIM: 601761) caspase-7 isoform g [Homo (311 aa)
initn: 1826 init1: 1826 opt: 1830 Z-score: 2291.7 bits: 432.1 E(85289): 6.5e-121
Smith-Waterman score: 1830; 96.8% identity (98.2% similar) in 278 aa overlap (26-303:36-311)
10 20 30 40 50
pF1KE1 MADEQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRV
:: ... . :::::::::::::::::::
NP_001 LKSRGLRIQQMKIQWMLSQTGPRLYRPSSAPDSGTLY--FTSKKKKNVTMRSIKTTRDRV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 PTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 CAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 EKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 GRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSML
250 260 270 280 290 300
300
pF1KE1 TKELYFSQ
::::::::
NP_001 TKELYFSQ
310
>>XP_016872253 (OMIM: 601761) PREDICTED: caspase-7 isofo (311 aa)
initn: 1826 init1: 1826 opt: 1830 Z-score: 2291.7 bits: 432.1 E(85289): 6.5e-121
Smith-Waterman score: 1830; 96.8% identity (98.2% similar) in 278 aa overlap (26-303:36-311)
10 20 30 40 50
pF1KE1 MADEQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRV
:: ... . :::::::::::::::::::
XP_016 LKSRGLRIQQMKIQWMLSQTGPRLYRPSSAPDSGTLY--FTSKKKKNVTMRSIKTTRDRV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 PTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 CAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 EKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 GRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSML
250 260 270 280 290 300
300
pF1KE1 TKELYFSQ
::::::::
XP_016 TKELYFSQ
310
>>XP_006718080 (OMIM: 601761) PREDICTED: caspase-7 isofo (317 aa)
initn: 1826 init1: 1826 opt: 1830 Z-score: 2291.6 bits: 432.2 E(85289): 6.6e-121
Smith-Waterman score: 1830; 96.8% identity (98.2% similar) in 278 aa overlap (26-303:42-317)
10 20 30 40 50
pF1KE1 MADEQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRV
:: ... . :::::::::::::::::::
XP_006 LKSRGLRIQQMKIQWMLSQTGPRLYRPSSAPDSGTLY--FTSKKKKNVTMRSIKTTRDRV
20 30 40 50 60
60 70 80 90 100 110
pF1KE1 PTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 CAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 EKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 GRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSML
250 260 270 280 290 300
300
pF1KE1 TKELYFSQ
::::::::
XP_006 TKELYFSQ
310
>>NP_001253987 (OMIM: 601761) caspase-7 isoform f [Homo (278 aa)
initn: 1826 init1: 1826 opt: 1829 Z-score: 2291.2 bits: 431.9 E(85289): 7e-121
Smith-Waterman score: 1829; 97.5% identity (98.2% similar) in 276 aa overlap (28-303:3-278)
10 20 30 40 50 60
pF1KE1 MADEQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
:. : . ::::::::::::::::::::::::
NP_001 MQRGLFSDGDTSKKKKNVTMRSIKTTRDRVPTYQY
10 20 30
70 80 90 100 110 120
pF1KE1 NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
220 230 240 250 260 270
pF1KE1 FSQ
:::
NP_001 FSQ
>>NP_001253986 (OMIM: 601761) caspase-7 isoform e [Homo (388 aa)
initn: 1826 init1: 1826 opt: 1830 Z-score: 2290.3 bits: 432.2 E(85289): 7.9e-121
Smith-Waterman score: 1830; 96.8% identity (98.2% similar) in 278 aa overlap (26-303:113-388)
10 20 30 40 50
pF1KE1 MADEQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRV
:: ... . :::::::::::::::::::
NP_001 LKSRGLRIQQMKIQWMLSQTGPRLYRPSSAPDSGTLY--FTSKKKKNVTMRSIKTTRDRV
90 100 110 120 130 140
60 70 80 90 100 110
pF1KE1 PTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCS
150 160 170 180 190 200
120 130 140 150 160 170
pF1KE1 CAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLL
210 220 230 240 250 260
180 190 200 210 220 230
pF1KE1 EKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSP
270 280 290 300 310 320
240 250 260 270 280 290
pF1KE1 GRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSML
330 340 350 360 370 380
300
pF1KE1 TKELYFSQ
::::::::
NP_001 TKELYFSQ
303 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:51:51 2016 done: Sun Nov 6 22:51:52 2016
Total Scan time: 7.140 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]