Result of FASTA (omim) for
pFN21AE1359
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1359, 410 aa
1>>>pF1KE1359 410 - 410 aa - 410 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4795+/-0.000311; mu= 16.3615+/- 0.020
mean_var=71.6486+/-14.455, 0's: 0 Z-trim(115.7): 55 B-trim: 245 in 1/56
Lambda= 0.151520
statistics sampled from 26247 (26319) to 26247 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.309), width: 16
Scan time: 8.690
The best scores are: opt bits E(85289)
NP_001229 (OMIM: 123837) G1/S-specific cyclin-E1 i ( 410) 2788 618.6 9e-177
XP_011525742 (OMIM: 123837) PREDICTED: G1/S-specif ( 407) 2752 610.7 2.1e-174
NP_001309191 (OMIM: 123837) G1/S-specific cyclin-E ( 395) 2686 596.2 4.5e-170
NP_001309188 (OMIM: 123837) G1/S-specific cyclin-E ( 365) 1610 361.0 2.7e-99
NP_001309190 (OMIM: 123837) G1/S-specific cyclin-E ( 361) 1407 316.6 6.1e-86
XP_016869448 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 1231 278.2 2.5e-74
XP_016869446 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 1231 278.2 2.5e-74
NP_477097 (OMIM: 603775) G1/S-specific cyclin-E2 [ ( 404) 1231 278.2 2.5e-74
XP_016869447 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 1231 278.2 2.5e-74
XP_011515668 (OMIM: 603775) PREDICTED: G1/S-specif ( 288) 873 199.9 6.9e-51
XP_011533597 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 343 84.1 7.1e-16
XP_011533598 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 343 84.1 7.1e-16
NP_001104517 (OMIM: 604036) cyclin-A1 isoform c [H ( 421) 343 84.1 7.1e-16
XP_011533596 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 343 84.1 7.1e-16
NP_001104516 (OMIM: 604036) cyclin-A1 isoform c [H ( 421) 343 84.1 7.1e-16
NP_001104515 (OMIM: 604036) cyclin-A1 isoform b [H ( 464) 343 84.1 7.7e-16
NP_003905 (OMIM: 604036) cyclin-A1 isoform a [Homo ( 465) 343 84.1 7.8e-16
NP_001228 (OMIM: 123835) cyclin-A2 [Homo sapiens] ( 432) 332 81.7 3.9e-15
NP_444284 (OMIM: 168461,193300,254500) G1/S-specif ( 295) 306 75.9 1.4e-13
NP_004692 (OMIM: 602755) G2/mitotic-specific cycli ( 398) 304 75.6 2.5e-13
NP_114172 (OMIM: 123836) G2/mitotic-specific cycli ( 433) 300 74.7 4.9e-13
NP_001751 (OMIM: 123834) G1/S-specific cyclin-D3 i ( 292) 285 71.3 3.5e-12
XP_011513273 (OMIM: 123834) PREDICTED: G1/S-specif ( 276) 273 68.7 2e-11
NP_001750 (OMIM: 123833,615938) G1/S-specific cycl ( 289) 271 68.3 2.9e-11
XP_016885407 (OMIM: 300456) PREDICTED: G2/mitotic- (1395) 276 69.7 5e-11
NP_149020 (OMIM: 300456) G2/mitotic-specific cycli (1395) 276 69.7 5e-11
XP_016885406 (OMIM: 300456) PREDICTED: G2/mitotic- (1396) 265 67.3 2.6e-10
XP_016885402 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 262 66.7 4.2e-10
XP_016885403 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 262 66.7 4.2e-10
XP_016885404 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 262 66.7 4.2e-10
XP_016885405 (OMIM: 300456) PREDICTED: G2/mitotic- (1403) 261 66.5 4.8e-10
NP_066970 (OMIM: 607752,615872) cyclin-O [Homo sap ( 350) 229 59.1 1.9e-08
NP_001274356 (OMIM: 123834) G1/S-specific cyclin-D ( 242) 214 55.8 1.4e-07
NP_391990 (OMIM: 300456) G2/mitotic-specific cycli ( 291) 178 47.9 3.8e-05
NP_001129489 (OMIM: 123834) G1/S-specific cyclin-D ( 211) 172 46.5 7.2e-05
XP_011530700 (OMIM: 603203) PREDICTED: cyclin-G2 i ( 344) 166 45.3 0.00027
NP_004345 (OMIM: 603203) cyclin-G2 [Homo sapiens] ( 344) 166 45.3 0.00027
XP_011530701 (OMIM: 603203) PREDICTED: cyclin-G2 i ( 344) 166 45.3 0.00027
XP_011513274 (OMIM: 123834) PREDICTED: G1/S-specif ( 195) 150 41.7 0.0019
>>NP_001229 (OMIM: 123837) G1/S-specific cyclin-E1 isofo (410 aa)
initn: 2788 init1: 2788 opt: 2788 Z-score: 3294.6 bits: 618.6 E(85289): 9e-177
Smith-Waterman score: 2788; 100.0% identity (100.0% similar) in 410 aa overlap (1-410:1-410)
10 20 30 40 50 60
pF1KE1 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNI
310 320 330 340 350 360
370 380 390 400 410
pF1KE1 QTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA
370 380 390 400 410
>>XP_011525742 (OMIM: 123837) PREDICTED: G1/S-specific c (407 aa)
initn: 2754 init1: 2529 opt: 2752 Z-score: 3252.1 bits: 610.7 E(85289): 2.1e-174
Smith-Waterman score: 2752; 99.3% identity (99.3% similar) in 410 aa overlap (1-410:1-407)
10 20 30 40 50 60
pF1KE1 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQ
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_011 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTV---DPDEEMAKIDRTARDQCGSQ
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 PWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 LNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 ENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 LSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILA
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 ASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNI
300 310 320 330 340 350
370 380 390 400 410
pF1KE1 QTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA
360 370 380 390 400
>>NP_001309191 (OMIM: 123837) G1/S-specific cyclin-E1 is (395 aa)
initn: 2686 init1: 2686 opt: 2686 Z-score: 3174.4 bits: 596.2 E(85289): 4.5e-170
Smith-Waterman score: 2686; 100.0% identity (100.0% similar) in 395 aa overlap (16-410:1-395)
10 20 30 40 50 60
pF1KE1 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQ
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQ
10 20 30 40
70 80 90 100 110 120
pF1KE1 PWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIM
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 LNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQ
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE1 ENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 LSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILA
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE1 ASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNI
290 300 310 320 330 340
370 380 390 400 410
pF1KE1 QTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA
350 360 370 380 390
>>NP_001309188 (OMIM: 123837) G1/S-specific cyclin-E1 is (365 aa)
initn: 1610 init1: 1610 opt: 1610 Z-score: 1903.7 bits: 361.0 E(85289): 2.7e-99
Smith-Waterman score: 2387; 89.0% identity (89.0% similar) in 410 aa overlap (1-410:1-365)
10 20 30 40 50 60
pF1KE1 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMK-----
190 200 210 220 230
250 260 270 280 290 300
pF1KE1 LSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILA
::::::::::::::::::::
NP_001 ----------------------------------------LLDLCVLDVDCLEFPYGILA
240 250
310 320 330 340 350 360
pF1KE1 ASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNI
260 270 280 290 300 310
370 380 390 400 410
pF1KE1 QTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA
320 330 340 350 360
>>NP_001309190 (OMIM: 123837) G1/S-specific cyclin-E1 is (361 aa)
initn: 1407 init1: 1407 opt: 1407 Z-score: 1663.9 bits: 316.6 E(85289): 6.1e-86
Smith-Waterman score: 2371; 88.0% identity (88.0% similar) in 410 aa overlap (1-410:1-361)
10 20 30 40 50 60
pF1KE1 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQ
::::::::::::::::::::::::::::::::::
NP_001 LNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLME--------------------------
130 140 150
190 200 210 220 230 240
pF1KE1 ENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWR
:::::::::::::::::::::::::::::::::::::
NP_001 -----------------------EIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWR
160 170 180 190
250 260 270 280 290 300
pF1KE1 LSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILA
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE1 ASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNI
260 270 280 290 300 310
370 380 390 400 410
pF1KE1 QTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA
320 330 340 350 360
>>XP_016869448 (OMIM: 603775) PREDICTED: G1/S-specific c (404 aa)
initn: 1220 init1: 1198 opt: 1231 Z-score: 1455.3 bits: 278.2 E(85289): 2.5e-74
Smith-Waterman score: 1231; 51.6% identity (75.0% similar) in 380 aa overlap (27-402:29-399)
10 20 30 40 50
pF1KE1 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCG
...:::.. : . ::..: . .:
XP_016 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDV--KKRREEVTKKHQYEIRNCW
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 SQPWDNNAVCADPCSLIPTPDKE---DDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREE
: .... .:: .: :: :: .: . : : .: : :::: :::. .:
XP_016 P-PVLSGGI--SPCIIIETPHKEIGTSDFSRFTNYRFKNLFINP---SPLPDLSWGCSKE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 VWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDR
:: ::.::. :..:.:: : :.:.::.::::::.:::::: :::::::::::::::
XP_016 VWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 YMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMK
.: ::... :..::::::.:::::.:::::: :::..:::::::::: ..:: :::.:.:
XP_016 FMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 ALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFP
::::.: :.::.::::...:: :.: .:::::: :. :::::.:::::.: .: :::
XP_016 ALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQ
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 YGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADE
: ::.:.:: ::.: :...:.:: .: .: .:: :::::. :.. :. ::: :. . :
XP_016 YRILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPME
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 DAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPL-PSGLLTPPQSGKKQSSGPEMA
: :::::: . : .:... .. . . .. ::. .:..:::.: .:
XP_016 DRHNIQTHTNYLAMLEEVNYINT-FRKGGQLSPVCNGGIMTPPKSTEKPPGKH
360 370 380 390 400
>>XP_016869446 (OMIM: 603775) PREDICTED: G1/S-specific c (404 aa)
initn: 1220 init1: 1198 opt: 1231 Z-score: 1455.3 bits: 278.2 E(85289): 2.5e-74
Smith-Waterman score: 1231; 51.6% identity (75.0% similar) in 380 aa overlap (27-402:29-399)
10 20 30 40 50
pF1KE1 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCG
...:::.. : . ::..: . .:
XP_016 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDV--KKRREEVTKKHQYEIRNCW
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 SQPWDNNAVCADPCSLIPTPDKE---DDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREE
: .... .:: .: :: :: .: . : : .: : :::: :::. .:
XP_016 P-PVLSGGI--SPCIIIETPHKEIGTSDFSRFTNYRFKNLFINP---SPLPDLSWGCSKE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 VWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDR
:: ::.::. :..:.:: : :.:.::.::::::.:::::: :::::::::::::::
XP_016 VWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 YMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMK
.: ::... :..::::::.:::::.:::::: :::..:::::::::: ..:: :::.:.:
XP_016 FMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 ALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFP
::::.: :.::.::::...:: :.: .:::::: :. :::::.:::::.: .: :::
XP_016 ALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQ
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 YGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADE
: ::.:.:: ::.: :...:.:: .: .: .:: :::::. :.. :. ::: :. . :
XP_016 YRILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPME
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 DAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPL-PSGLLTPPQSGKKQSSGPEMA
: :::::: . : .:... .. . . .. ::. .:..:::.: .:
XP_016 DRHNIQTHTNYLAMLEEVNYINT-FRKGGQLSPVCNGGIMTPPKSTEKPPGKH
360 370 380 390 400
>>NP_477097 (OMIM: 603775) G1/S-specific cyclin-E2 [Homo (404 aa)
initn: 1220 init1: 1198 opt: 1231 Z-score: 1455.3 bits: 278.2 E(85289): 2.5e-74
Smith-Waterman score: 1231; 51.6% identity (75.0% similar) in 380 aa overlap (27-402:29-399)
10 20 30 40 50
pF1KE1 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCG
...:::.. : . ::..: . .:
NP_477 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDV--KKRREEVTKKHQYEIRNCW
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 SQPWDNNAVCADPCSLIPTPDKE---DDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREE
: .... .:: .: :: :: .: . : : .: : :::: :::. .:
NP_477 P-PVLSGGI--SPCIIIETPHKEIGTSDFSRFTNYRFKNLFINP---SPLPDLSWGCSKE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 VWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDR
:: ::.::. :..:.:: : :.:.::.::::::.:::::: :::::::::::::::
NP_477 VWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 YMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMK
.: ::... :..::::::.:::::.:::::: :::..:::::::::: ..:: :::.:.:
NP_477 FMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 ALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFP
::::.: :.::.::::...:: :.: .:::::: :. :::::.:::::.: .: :::
NP_477 ALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQ
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 YGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADE
: ::.:.:: ::.: :...:.:: .: .: .:: :::::. :.. :. ::: :. . :
NP_477 YRILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPME
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 DAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPL-PSGLLTPPQSGKKQSSGPEMA
: :::::: . : .:... .. . . .. ::. .:..:::.: .:
NP_477 DRHNIQTHTNYLAMLEEVNYINT-FRKGGQLSPVCNGGIMTPPKSTEKPPGKH
360 370 380 390 400
>>XP_016869447 (OMIM: 603775) PREDICTED: G1/S-specific c (404 aa)
initn: 1220 init1: 1198 opt: 1231 Z-score: 1455.3 bits: 278.2 E(85289): 2.5e-74
Smith-Waterman score: 1231; 51.6% identity (75.0% similar) in 380 aa overlap (27-402:29-399)
10 20 30 40 50
pF1KE1 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCG
...:::.. : . ::..: . .:
XP_016 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDV--KKRREEVTKKHQYEIRNCW
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 SQPWDNNAVCADPCSLIPTPDKE---DDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREE
: .... .:: .: :: :: .: . : : .: : :::: :::. .:
XP_016 P-PVLSGGI--SPCIIIETPHKEIGTSDFSRFTNYRFKNLFINP---SPLPDLSWGCSKE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 VWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDR
:: ::.::. :..:.:: : :.:.::.::::::.:::::: :::::::::::::::
XP_016 VWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 YMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMK
.: ::... :..::::::.:::::.:::::: :::..:::::::::: ..:: :::.:.:
XP_016 FMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 ALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFP
::::.: :.::.::::...:: :.: .:::::: :. :::::.:::::.: .: :::
XP_016 ALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQ
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 YGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADE
: ::.:.:: ::.: :...:.:: .: .: .:: :::::. :.. :. ::: :. . :
XP_016 YRILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPME
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 DAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPL-PSGLLTPPQSGKKQSSGPEMA
: :::::: . : .:... .. . . .. ::. .:..:::.: .:
XP_016 DRHNIQTHTNYLAMLEEVNYINT-FRKGGQLSPVCNGGIMTPPKSTEKPPGKH
360 370 380 390 400
>>XP_011515668 (OMIM: 603775) PREDICTED: G1/S-specific c (288 aa)
initn: 868 init1: 846 opt: 873 Z-score: 1034.5 bits: 199.9 E(85289): 6.9e-51
Smith-Waterman score: 873; 54.4% identity (75.7% similar) in 259 aa overlap (27-282:29-279)
10 20 30 40 50
pF1KE1 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCG
...:::.. : . ::..: . .:
XP_011 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDV--KKRREEVTKKHQYEIRNCW
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 SQPWDNNAVCADPCSLIPTPDKE---DDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREE
: .... .:: .: :: :: .: . : : .: : :::: :::. .:
XP_011 P-PVLSGGI--SPCIIIETPHKEIGTSDFSRFTNYRFKNLFINP---SPLPDLSWGCSKE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 VWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDR
:: ::.::. :..:.:: : :.:.::.::::::.:::::: :::::::::::::::
XP_011 VWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 YMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMK
.: ::... :..::::::.:::::.:::::: :::..:::::::::: ..:: :::.:.:
XP_011 FMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 ALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFP
::::.: :.::.::::...:: :.: .:::::: :. :::::.:.
XP_011 ALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLFSHFSYLLDQ
240 250 260 270 280
300 310 320 330 340 350
pF1KE1 YGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADE
410 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:51:55 2016 done: Sun Nov 6 23:51:57 2016
Total Scan time: 8.690 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]