Result of FASTA (omim) for
pFN21AE1357
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1357, 152 aa
1>>>pF1KE1357 152 - 152 aa - 152 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3496+/-0.000264; mu= 11.7839+/- 0.017
mean_var=62.8768+/-12.566, 0's: 0 Z-trim(119.8): 129 B-trim: 0 in 0/56
Lambda= 0.161744
statistics sampled from 34097 (34234) to 34097 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.786), E-opt: 0.2 (0.401), width: 16
Scan time: 5.490
The best scores are: opt bits E(85289)
NP_003327 (OMIM: 300860,312180) ubiquitin-conjugat ( 152) 1039 250.1 1e-66
NP_003328 (OMIM: 179095) ubiquitin-conjugating enz ( 152) 993 239.3 1.8e-63
NP_001269090 (OMIM: 300860,312180) ubiquitin-conju ( 119) 816 198.0 3.9e-51
NP_861427 (OMIM: 300860,312180) ubiquitin-conjugat ( 122) 485 120.8 7e-28
NP_003329 (OMIM: 602961) ubiquitin-conjugating enz ( 147) 446 111.7 4.5e-25
NP_003330 (OMIM: 602962) ubiquitin-conjugating enz ( 147) 440 110.3 1.2e-24
NP_871617 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 438 109.8 1.7e-24
NP_871616 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 438 109.8 1.7e-24
NP_871619 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 438 109.8 1.7e-24
NP_003331 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 438 109.8 1.7e-24
NP_871620 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 438 109.8 1.7e-24
NP_871618 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 438 109.8 1.7e-24
NP_871615 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 438 109.8 1.7e-24
NP_871621 (OMIM: 602963) ubiquitin-conjugating enz ( 148) 437 109.6 2e-24
NP_871622 (OMIM: 602963) ubiquitin-conjugating enz ( 149) 435 109.1 2.7e-24
NP_003339 (OMIM: 603679) ubiquitin-conjugating enz ( 152) 425 106.8 1.4e-23
XP_016865309 (OMIM: 602962) PREDICTED: ubiquitin-c ( 173) 424 106.6 1.8e-23
NP_919237 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 418 105.2 4.5e-23
NP_003336 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 418 105.2 4.5e-23
XP_016879129 (OMIM: 601661) PREDICTED: SUMO-conjug ( 158) 418 105.2 4.5e-23
NP_919235 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 418 105.2 4.5e-23
NP_919236 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 418 105.2 4.5e-23
NP_008950 (OMIM: 605574) ubiquitin-conjugating enz ( 179) 408 102.9 2.5e-22
NP_001189405 (OMIM: 602916) ubiquitin-conjugating ( 160) 402 101.4 6e-22
NP_003332 (OMIM: 602916) ubiquitin-conjugating enz ( 193) 398 100.5 1.4e-21
NP_689866 (OMIM: 602163) ubiquitin-conjugating enz ( 201) 393 99.4 3.1e-21
XP_005265489 (OMIM: 602163) PREDICTED: ubiquitin-c ( 201) 393 99.4 3.1e-21
NP_872619 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 391 98.9 4.5e-21
NP_001265484 (OMIM: 604151) ubiquitin-conjugating ( 207) 391 98.9 4.5e-21
NP_006348 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 391 98.9 4.5e-21
XP_005246301 (OMIM: 604151) PREDICTED: ubiquitin-c ( 207) 391 98.9 4.5e-21
NP_001265483 (OMIM: 604151) ubiquitin-conjugating ( 207) 391 98.9 4.5e-21
NP_861517 (OMIM: 605574) ubiquitin-conjugating enz ( 140) 386 97.7 7.1e-21
NP_862821 (OMIM: 602962) ubiquitin-conjugating enz ( 118) 377 95.5 2.6e-20
NP_001287724 (OMIM: 602963) ubiquitin-conjugating ( 118) 376 95.3 3.1e-20
XP_016864073 (OMIM: 602963) PREDICTED: ubiquitin-c ( 118) 376 95.3 3.1e-20
XP_005265488 (OMIM: 602916) PREDICTED: ubiquitin-c ( 167) 376 95.4 4.2e-20
XP_011520946 (OMIM: 601661) PREDICTED: SUMO-conjug ( 184) 370 94.0 1.2e-19
XP_005255598 (OMIM: 601661) PREDICTED: SUMO-conjug ( 184) 370 94.0 1.2e-19
XP_011520947 (OMIM: 601661) PREDICTED: SUMO-conjug ( 184) 370 94.0 1.2e-19
XP_005255597 (OMIM: 601661) PREDICTED: SUMO-conjug ( 184) 370 94.0 1.2e-19
NP_055316 (OMIM: 610309) ubiquitin-conjugating enz ( 222) 370 94.0 1.4e-19
NP_054895 (OMIM: 610538,616435) ubiquitin-conjugat ( 197) 362 92.1 4.7e-19
XP_005265490 (OMIM: 602163) PREDICTED: ubiquitin-c ( 189) 360 91.7 6.2e-19
NP_872607 (OMIM: 602916) ubiquitin-conjugating enz ( 176) 354 90.3 1.5e-18
XP_016872098 (OMIM: 602961) PREDICTED: ubiquitin-c ( 110) 349 89.0 2.3e-18
NP_003335 (OMIM: 601082) ubiquitin-conjugating enz ( 183) 346 88.4 5.8e-18
NP_001191809 (OMIM: 602961) ubiquitin-conjugating ( 109) 333 85.3 3e-17
NP_861516 (OMIM: 605574) ubiquitin-conjugating enz ( 150) 324 83.2 1.7e-16
NP_001297255 (OMIM: 610538,616435) ubiquitin-conju ( 167) 317 81.6 5.9e-16
>>NP_003327 (OMIM: 300860,312180) ubiquitin-conjugating (152 aa)
initn: 1039 init1: 1039 opt: 1039 Z-score: 1318.7 bits: 250.1 E(85289): 1e-66
Smith-Waterman score: 1039; 100.0% identity (100.0% similar) in 152 aa overlap (1-152:1-152)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
70 80 90 100 110 120
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWRDC
::::::::::::::::::::::::::::::::
NP_003 PANSQAAQLYQENKREYEKRVSAIVEQSWRDC
130 140 150
>>NP_003328 (OMIM: 179095) ubiquitin-conjugating enzyme (152 aa)
initn: 1006 init1: 993 opt: 993 Z-score: 1260.7 bits: 239.3 E(85289): 1.8e-63
Smith-Waterman score: 993; 96.0% identity (98.7% similar) in 151 aa overlap (1-151:1-151)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFT
:::::::::::::::::::::.:::::::::::: ::::::::::::::::::::.:::.
NP_003 MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
70 80 90 100 110 120
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWRDC
::::::::::::::::::::::::::::: :
NP_003 PANSQAAQLYQENKREYEKRVSAIVEQSWNDS
130 140 150
>>NP_001269090 (OMIM: 300860,312180) ubiquitin-conjugati (119 aa)
initn: 816 init1: 816 opt: 816 Z-score: 1039.1 bits: 198.0 E(85289): 3.9e-51
Smith-Waterman score: 816; 100.0% identity (100.0% similar) in 119 aa overlap (34-152:1-119)
10 20 30 40 50 60
pF1KE1 PARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEY
::::::::::::::::::::::::::::::
NP_001 MVWNAVIFGPEGTPFEDGTFKLTIEFTEEY
10 20 30
70 80 90 100 110 120
pF1KE1 PNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPAN
40 50 60 70 80 90
130 140 150
pF1KE1 SQAAQLYQENKREYEKRVSAIVEQSWRDC
:::::::::::::::::::::::::::::
NP_001 SQAAQLYQENKREYEKRVSAIVEQSWRDC
100 110
>>NP_861427 (OMIM: 300860,312180) ubiquitin-conjugating (122 aa)
initn: 485 init1: 485 opt: 485 Z-score: 621.5 bits: 120.8 E(85289): 7e-28
Smith-Waterman score: 762; 80.3% identity (80.3% similar) in 152 aa overlap (1-152:1-122)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFT
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_861 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFED----------
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
::::::::::::::::::::::::::::::::::::::::
NP_861 --------------------VYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
60 70 80 90
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWRDC
::::::::::::::::::::::::::::::::
NP_861 PANSQAAQLYQENKREYEKRVSAIVEQSWRDC
100 110 120
>>NP_003329 (OMIM: 602961) ubiquitin-conjugating enzyme (147 aa)
initn: 444 init1: 428 opt: 446 Z-score: 571.0 bits: 111.7 E(85289): 4.5e-25
Smith-Waterman score: 446; 43.0% identity (79.3% similar) in 135 aa overlap (5-139:2-136)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFT
: .:...... ::.:::: :..: .... :.:.:.:: . .. :.: ::..:
NP_003 MALKRIQKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFP
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
.:: ::: . :..:..:::. ..::::::::...:::. ::..: :: ::: .:::..
NP_003 TDYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDD
60 70 80 90 100 110
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWRDC
: . ::.:. .:..:..
NP_003 PLVPDIAQIYKSDKEKYNRHAREWTQKYAM
120 130 140
>>NP_003330 (OMIM: 602962) ubiquitin-conjugating enzyme (147 aa)
initn: 402 init1: 390 opt: 440 Z-score: 563.5 bits: 110.3 E(85289): 1.2e-24
Smith-Waterman score: 440; 41.5% identity (79.3% similar) in 135 aa overlap (5-139:2-136)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFT
: .:. .... : .:::: :..: .... :.:.:.::. .:.. :.: :::.:
NP_003 MALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFP
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
.:: ::: : :.....:::. ..::::::::...:::. .:..: :: ::: .:::..
NP_003 TDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWRDC
: . :..:. ....:..
NP_003 PLVPEIARIYKTDREKYNRIAREWTQKYAM
120 130 140
>>NP_871617 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 402 init1: 390 opt: 438 Z-score: 561.0 bits: 109.8 E(85289): 1.7e-24
Smith-Waterman score: 438; 42.0% identity (78.3% similar) in 138 aa overlap (5-142:2-138)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFT
: .:. .... : .:::: :..: .... :.:.:.::. .:.. :.: :::.:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFP
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
.:: ::: : :.....:::. ..::::::::...:::. .:..: :: ::: .:::..
NP_871 TDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWRDC
: . :..:. .. .:. :.:
NP_871 PLVPEIARIYKTDRDKYN-RISREWTQKYAM
120 130 140
>>NP_871616 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 402 init1: 390 opt: 438 Z-score: 561.0 bits: 109.8 E(85289): 1.7e-24
Smith-Waterman score: 438; 42.0% identity (78.3% similar) in 138 aa overlap (5-142:2-138)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFT
: .:. .... : .:::: :..: .... :.:.:.::. .:.. :.: :::.:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFP
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
.:: ::: : :.....:::. ..::::::::...:::. .:..: :: ::: .:::..
NP_871 TDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWRDC
: . :..:. .. .:. :.:
NP_871 PLVPEIARIYKTDRDKYN-RISREWTQKYAM
120 130 140
>>NP_871619 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 402 init1: 390 opt: 438 Z-score: 561.0 bits: 109.8 E(85289): 1.7e-24
Smith-Waterman score: 438; 42.0% identity (78.3% similar) in 138 aa overlap (5-142:2-138)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFT
: .:. .... : .:::: :..: .... :.:.:.::. .:.. :.: :::.:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFP
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
.:: ::: : :.....:::. ..::::::::...:::. .:..: :: ::: .:::..
NP_871 TDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWRDC
: . :..:. .. .:. :.:
NP_871 PLVPEIARIYKTDRDKYN-RISREWTQKYAM
120 130 140
>>NP_003331 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 402 init1: 390 opt: 438 Z-score: 561.0 bits: 109.8 E(85289): 1.7e-24
Smith-Waterman score: 438; 42.0% identity (78.3% similar) in 138 aa overlap (5-142:2-138)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFT
: .:. .... : .:::: :..: .... :.:.:.::. .:.. :.: :::.:
NP_003 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFP
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
.:: ::: : :.....:::. ..::::::::...:::. .:..: :: ::: .:::..
NP_003 TDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWRDC
: . :..:. .. .:. :.:
NP_003 PLVPEIARIYKTDRDKYN-RISREWTQKYAM
120 130 140
152 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:05:44 2016 done: Sun Nov 6 23:05:44 2016
Total Scan time: 5.490 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]