FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1347, 379 aa
  1>>>pF1KE1347 379 - 379 aa - 379 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.0142+/-0.000346; mu= 9.5507+/- 0.022
 mean_var=110.4194+/-22.979, 0's: 0 Z-trim(118.0): 10  B-trim: 1577 in 2/55
 Lambda= 0.122054
 statistics sampled from 30449 (30459) to 30449 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.357), width:  16
 Scan time: 10.020

The best scores are:                                      opt bits E(85289)
NP_919410 (OMIM: 605392) FGFR1 oncogene partner is ( 379) 2381 429.7 5.5e-120
NP_008976 (OMIM: 605392) FGFR1 oncogene partner is ( 399) 1343 246.9   6e-65
NP_001265619 (OMIM: 605392) FGFR1 oncogene partner ( 351) 1170 216.4 7.9e-56


>>NP_919410 (OMIM: 605392) FGFR1 oncogene partner isofor  (379 aa)
 initn: 2381 init1: 2381 opt: 2381  Z-score: 2275.2  bits: 429.7 E(85289): 5.5e-120
Smith-Waterman score: 2381; 99.5% identity (100.0% similar) in 379 aa overlap (1-379:1-379)

               10        20        30        40        50        60
pF1KE1 MAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 MAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 SLRKFLNTKDGRLVASLVAEFLQFFNLDFTLAVFQPETSTLQGLEGRENLARDLGIIEAE
       ::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 SLKKFLNTKDGRLVASLVAEFLQFFNLDFTLAVFQPETSTLQGLEGRENLARDLGIIEAE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 GTVGGPLLLEVIRRCQQKEKGPTTGEGALDLSDVHSPPKSPEGKTSAQTTPSKKANDEAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 GTVGGPLLLEVIRRCQQKEKGPTTGEGALDLSDVHSPPKSPEGKTSAQTTPSKKANDEAN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 QSDTSVSLSEPKSKSSLHLLSHETKIGSFLSNRTLDGKDKAGLCPDEDDMEGDSFFDDPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 QSDTSVSLSEPKSKSSLHLLSHETKIGSFLSNRTLDGKDKAGLCPDEDDMEGDSFFDDPI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 PKPEKTYGLRNEPRKQAGSLASLSDAPPLKSGLSSLAGAPSLKDSESKRGNTVLKDLKLI
       ::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 PKPEKTYGLRKEPRKQAGSLASLSDAPPLKSGLSSLAGAPSLKDSESKRGNTVLKDLKLI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 SDKIGSLGLGTGEDDDYVDDFNSTSHRSEKSEISIGEEIEEDLSVEIDDINTSDKLDDLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 SDKIGSLGLGTGEDDDYVDDFNSTSHRSEKSEISIGEEIEEDLSVEIDDINTSDKLDDLT
              310       320       330       340       350       360

              370         
pF1KE1 QDLTVSQLSDVADYLEDVA
       :::::::::::::::::::
NP_919 QDLTVSQLSDVADYLEDVA
              370         

>>NP_008976 (OMIM: 605392) FGFR1 oncogene partner isofor  (399 aa)
 initn: 1335 init1: 1335 opt: 1343  Z-score: 1287.0  bits: 246.9 E(85289): 6e-65
Smith-Waterman score: 2331; 94.5% identity (95.0% similar) in 399 aa overlap (1-379:1-399)

               10        20        30        40        50        60
pF1KE1 MAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 SLRKFLNTKDGRLVASLVAEFLQFFNLDFTLAVFQPETSTLQGLEGRENLARDLGIIEAE
       ::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 SLKKFLNTKDGRLVASLVAEFLQFFNLDFTLAVFQPETSTLQGLEGRENLARDLGIIEAE
               70        80        90       100       110       120

              130       140       150       160       170          
pF1KE1 GTVGGPLLLEVIRRCQQKEKGPTTGEGALDLSDVHSPPKSPEGKTSAQTTPSK-------
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
NP_008 GTVGGPLLLEVIRRCQQKEKGPTTGEGALDLSDVHSPPKSPEGKTSAQTTPSKIPRYKGQ
              130       140       150       160       170       180

                        180       190       200       210       220
pF1KE1 -------------KANDEANQSDTSVSLSEPKSKSSLHLLSHETKIGSFLSNRTLDGKDK
                    :::::::::::::::::::::::::::::::::::::::::::::::
NP_008 GKKKTSGQKAGDKKANDEANQSDTSVSLSEPKSKSSLHLLSHETKIGSFLSNRTLDGKDK
              190       200       210       220       230       240

              230       240       250       260       270       280
pF1KE1 AGLCPDEDDMEGDSFFDDPIPKPEKTYGLRNEPRKQAGSLASLSDAPPLKSGLSSLAGAP
       ::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_008 AGLCPDEDDMEGDSFFDDPIPKPEKTYGLRKEPRKQAGSLASLSDAPPLKSGLSSLAGAP
              250       260       270       280       290       300

              290       300       310       320       330       340
pF1KE1 SLKDSESKRGNTVLKDLKLISDKIGSLGLGTGEDDDYVDDFNSTSHRSEKSEISIGEEIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 SLKDSESKRGNTVLKDLKLISDKIGSLGLGTGEDDDYVDDFNSTSHRSEKSEISIGEEIE
              310       320       330       340       350       360

              350       360       370         
pF1KE1 EDLSVEIDDINTSDKLDDLTQDLTVSQLSDVADYLEDVA
       :::::::::::::::::::::::::::::::::::::::
NP_008 EDLSVEIDDINTSDKLDDLTQDLTVSQLSDVADYLEDVA
              370       380       390         

>>NP_001265619 (OMIM: 605392) FGFR1 oncogene partner iso  (351 aa)
 initn: 1168 init1: 1168 opt: 1170  Z-score: 1123.2  bits: 216.4 E(85289): 7.9e-56
Smith-Waterman score: 1995; 88.0% identity (90.7% similar) in 376 aa overlap (1-373:1-349)

               10        20        30        40        50        60
pF1KE1 MAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 SLRKFLNTKDGRLVASLVAEFLQFFNLDFTLAVFQPETSTLQGLEGRENLARDLGIIEAE
       ::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLKKFLNTKDGRLVASLVAEFLQFFNLDFTLAVFQPETSTLQGLEGRENLARDLGIIEAE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 GTVGGPLLLEVIRRCQQKEKGPTTGEGALDLSDVHSPPKSPEGKTSAQTTPSKKANDEAN
       ::::::::::::::::::::::::::                           :::::::
NP_001 GTVGGPLLLEVIRRCQQKEKGPTTGE---------------------------KANDEAN
              130       140                                  150   

              190       200       210       220       230       240
pF1KE1 QSDTSVSLSEPKSKSSLHLLSHETKIGSFLSNRTLDGKDKAGLCPDEDDMEGDSFFDDPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSDTSVSLSEPKSKSSLHLLSHETKIGSFLSNRTLDGKDKAGLCPDEDDMEGDSFFDDPI
           160       170       180       190       200       210   

              250       260       270       280       290       300
pF1KE1 PKPEKTYGLRNEPRKQAGSLASLSDAPPLKSGLSSLAGAPSLKDSESKRGNTVLKDLKLI
       ::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKPEKTYGLRKEPRKQAGSLASLSDAPPLKSGLSSLAGAPSLKDSESKRGNTVLKDLKLI
           220       230       240       250       260       270   

              310       320       330       340       350          
pF1KE1 SDKIGSLGLGTGEDDDYVDDFNSTSHRSEKSEISIGEEIEEDLSVEIDDINTSDK-LDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::: . .:
NP_001 SDKIGSLGLGTGEDDDYVDDFNSTSHRSEKSEISIGEEIEEDLSVEIDDINTSDKTITQL
           280       290       300       310       320       330   

     360         370         
pF1KE1 TQDLTVSQL--SDVADYLEDVA
          :... :  ...::      
NP_001 ECLLSIGALHFKNTADIF    
           340       350     




379 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 01:46:57 2016 done: Mon Nov  7 01:46:58 2016
 Total Scan time: 10.020 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]