Result of FASTA (omim) for
pFN21AE1325
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1325, 502 aa
1>>>pF1KE1325 502 - 502 aa - 502 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.8806+/-0.000482; mu= -27.7209+/- 0.030
mean_var=905.1992+/-186.480, 0's: 0 Z-trim(126.1): 91 B-trim: 0 in 0/62
Lambda= 0.042629
statistics sampled from 51266 (51456) to 51266 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.832), E-opt: 0.2 (0.603), width: 16
Scan time: 10.140
The best scores are: opt bits E(85289)
NP_000368 (OMIM: 300299,300392,313900) wiskott-Ald ( 502) 3619 237.7 6e-62
XP_016885275 (OMIM: 300299,300392,313900) PREDICTE ( 590) 3487 229.7 1.8e-59
XP_011542279 (OMIM: 300299,300392,313900) PREDICTE ( 450) 2367 160.7 8.4e-39
NP_003932 (OMIM: 605056) neural Wiskott-Aldrich sy ( 505) 863 68.2 6.3e-11
XP_016857330 (OMIM: 606373,616193) PREDICTED: form (1102) 458 43.7 0.0034
XP_016857329 (OMIM: 606373,616193) PREDICTED: form (1102) 458 43.7 0.0034
XP_016857328 (OMIM: 606373,616193) PREDICTED: form (1159) 458 43.7 0.0035
XP_011542539 (OMIM: 606373,616193) PREDICTED: form (1360) 458 43.8 0.0039
XP_016857327 (OMIM: 606373,616193) PREDICTED: form (1384) 458 43.8 0.0039
XP_016857326 (OMIM: 606373,616193) PREDICTED: form (1417) 458 43.8 0.004
NP_064450 (OMIM: 606373,616193) formin-2 isoform 2 (1722) 458 43.9 0.0046
NP_001292353 (OMIM: 606373,616193) formin-2 isofor (1726) 458 43.9 0.0046
>>NP_000368 (OMIM: 300299,300392,313900) wiskott-Aldrich (502 aa)
initn: 3619 init1: 3619 opt: 3619 Z-score: 1233.2 bits: 237.7 E(85289): 6e-62
Smith-Waterman score: 3619; 100.0% identity (100.0% similar) in 502 aa overlap (1-502:1-502)
10 20 30 40 50 60
pF1KE1 MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 PSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 PAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRA
430 440 450 460 470 480
490 500
pF1KE1 IHSSDEGEDQAGDEDEDDEWDD
::::::::::::::::::::::
NP_000 IHSSDEGEDQAGDEDEDDEWDD
490 500
>>XP_016885275 (OMIM: 300299,300392,313900) PREDICTED: w (590 aa)
initn: 3482 init1: 3482 opt: 3487 Z-score: 1188.5 bits: 229.7 E(85289): 1.8e-59
Smith-Waterman score: 3487; 98.8% identity (99.6% similar) in 493 aa overlap (1-492:1-493)
10 20 30 40 50 60
pF1KE1 MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 PSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 PAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRA
430 440 450 460 470 480
490 500
pF1KE1 IHSS-DEGEDQAGDEDEDDEWDD
:::: ... .:::
XP_016 IHSSGSRSVSQAGVQWCNHGSVQPQPPRLKRSSRLSSQSSWDYRRVPPYLANFWCFFGSD
490 500 510 520 530 540
>>XP_011542279 (OMIM: 300299,300392,313900) PREDICTED: w (450 aa)
initn: 2221 init1: 2221 opt: 2367 Z-score: 817.6 bits: 160.7 E(85289): 8.4e-39
Smith-Waterman score: 3090; 89.6% identity (89.6% similar) in 502 aa overlap (1-502:1-450)
10 20 30 40 50 60
pF1KE1 MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 PSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPP
::::::::::
XP_011 EAVRQEMRRQ--------------------------------------------------
310
370 380 390 400 410 420
pF1KE1 PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 --GRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV
320 330 340 350 360
430 440 450 460 470 480
pF1KE1 PAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRA
370 380 390 400 410 420
490 500
pF1KE1 IHSSDEGEDQAGDEDEDDEWDD
::::::::::::::::::::::
XP_011 IHSSDEGEDQAGDEDEDDEWDD
430 440 450
>>NP_003932 (OMIM: 605056) neural Wiskott-Aldrich syndro (505 aa)
initn: 1526 init1: 606 opt: 863 Z-score: 317.1 bits: 68.2 E(85289): 6.3e-11
Smith-Waterman score: 1546; 48.3% identity (66.6% similar) in 530 aa overlap (16-498:11-499)
10 20 30 40 50 60
pF1KE1 MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG
: :. : :: .::. :: .::.::.:...:::::: :
NP_003 MSSVQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAA--DR
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD
:.:. :..:.::::::.:::.:.. .. :.::::::::...::..: .:::::::
NP_003 NCMWSKKCSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH
::..::::.:.::. :: : . . .: ::.: ::.
NP_003 TCQVALNFANEEEAKKFRKAVTDLLGRR-QRKSEKRRD----------------------
120 130 140 150
190 200 210 220 230
pF1KE1 PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGK---KKISKAD
:: :: .: .:::::.::.::..:. : . . : . .:..:: :...:::
NP_003 -------PPNGP-NLPMATVDIKNPEITTNRFYGPQVNNISHTKEKKKGKAKKKRLTKAD
160 170 180 190 200
240 250 260 270 280 290
pF1KE1 IGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQ
::.::.:.:..::::::..:::.:::::.:..::. ::::::: : ::::.::::::
NP_003 IGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKT
210 220 230 240 250 260
300 310 320 330 340
pF1KE1 GGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGN------KGRSGPLPP---VPLG
::.:::..:.::: : ::::::::: : :: ... .::..: :: .: .
NP_003 GGVEAVKNELRRQAP--PPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTA
270 280 290 300 310 320
350 360 370 380 390 400
pF1KE1 IAPPPPTPRG-----PPPPGRGGPPPPPP-PATGRSGPLPPPPPGAG-GPPMPPPPPPPP
:::: : ::::.: ::::: :... ::: :::: : :: ::::::::
NP_003 APPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPP
330 340 350 360 370 380
410 420 430
pF1KE1 PPPSSGNGPAPPPLPPA----LVP--AGGLAP-------GG---------------GRGA
::: :: ::: :. :: ::. : :. :: :
NP_003 PPP----GPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDA
390 400 410 420 430
440 450 460 470 480 490
pF1KE1 LLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRAIHSSDEGEDQAGD
:::::::::::... . ::. : : . :.:::::.::::::.::::::: ::. .
NP_003 LLDQIRQGIQLKSVADGQESTP--PTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDE
440 450 460 470 480 490
500
pF1KE1 EDEDDEWDD
:: .:
NP_003 EDFEDDDEWED
500
>>XP_016857330 (OMIM: 606373,616193) PREDICTED: formin-2 (1102 aa)
initn: 313 init1: 313 opt: 458 Z-score: 178.4 bits: 43.7 E(85289): 0.0034
Smith-Waterman score: 503; 31.1% identity (48.5% similar) in 379 aa overlap (116-466:96-454)
90 100 110 120 130 140
pF1KE1 RLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGDDCQAGLNFADEDEAQAFRALVQEKI
: .:: : .: . .: :.. : : ..:
XP_016 LRTKIAELERQYPALDTEVASGHQGLENGVTASGDVCLEALRL-EEKEVRHHRILEAKSI
70 80 90 100 110 120
150 160 170 180 190 200
pF1KE1 QKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPV---GPLSLGLAT--V
: ...: : ::. ::: : : : ..:: . . .:: .. .
XP_016 QTSPTEEGG---VLTLPPVD-------GLPGRPPCPPGAESGPQTKFCSEISLIVSPRRI
130 140 150 160 170
210 220 230 240 250
pF1KE1 DIQNPDITSSRYRGLPAPGPS---PADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNG
..: . .. . : : :: : . . :.. .:.. .: :. .:.
XP_016 SVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQP--PHSISTEFQTSHEHSVSSAFKNS
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE1 FDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQE--MRRQEPLPP
.. . : : : ... .. : . . :. : .. : :::
XP_016 CNIPS-PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPST-AIPQPPPLQGTEMLPP
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE1 PPPPSRGGNQLPRPPIVGGNKGRSGPLPPVP-LGIAPPPPTPRG---PPPPGRGGPPPPP
:::: :.. : ::. :.. ::::.: :: :::: : . :::: :. : :
XP_016 PPPPLPGAGIPPPPPLPGAGI---LPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLP
300 310 320 330 340
380 390 400 410
pF1KE1 PPATGRSGPLPPPPPGAGGPPMPP------PPPPP-------PPPPSSGNG-PAPPPLPP
:: : . : ::: :::: :: :: ::::: :::: : : : :::::
XP_016 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE1 ALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKR
: .: ::.: : . : : .. ::: . :.
XP_016 AGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI
410 420 430 440 450 460
480 490 500
pF1KE1 SRAIHSSDEGEDQAGDEDEDDEWDD
XP_016 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP
470 480 490 500 510 520
>>XP_016857329 (OMIM: 606373,616193) PREDICTED: formin-2 (1102 aa)
initn: 313 init1: 313 opt: 458 Z-score: 178.4 bits: 43.7 E(85289): 0.0034
Smith-Waterman score: 503; 31.1% identity (48.5% similar) in 379 aa overlap (116-466:96-454)
90 100 110 120 130 140
pF1KE1 RLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGDDCQAGLNFADEDEAQAFRALVQEKI
: .:: : .: . .: :.. : : ..:
XP_016 LRTKIAELERQYPALDTEVASGHQGLENGVTASGDVCLEALRL-EEKEVRHHRILEAKSI
70 80 90 100 110 120
150 160 170 180 190 200
pF1KE1 QKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPV---GPLSLGLAT--V
: ...: : ::. ::: : : : ..:: . . .:: .. .
XP_016 QTSPTEEGG---VLTLPPVD-------GLPGRPPCPPGAESGPQTKFCSEISLIVSPRRI
130 140 150 160 170
210 220 230 240 250
pF1KE1 DIQNPDITSSRYRGLPAPGPS---PADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNG
..: . .. . : : :: : . . :.. .:.. .: :. .:.
XP_016 SVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQP--PHSISTEFQTSHEHSVSSAFKNS
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE1 FDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQE--MRRQEPLPP
.. . : : : ... .. : . . :. : .. : :::
XP_016 CNIPS-PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPST-AIPQPPPLQGTEMLPP
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE1 PPPPSRGGNQLPRPPIVGGNKGRSGPLPPVP-LGIAPPPPTPRG---PPPPGRGGPPPPP
:::: :.. : ::. :.. ::::.: :: :::: : . :::: :. : :
XP_016 PPPPLPGAGIPPPPPLPGAGI---LPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLP
300 310 320 330 340
380 390 400 410
pF1KE1 PPATGRSGPLPPPPPGAGGPPMPP------PPPPP-------PPPPSSGNG-PAPPPLPP
:: : . : ::: :::: :: :: ::::: :::: : : : :::::
XP_016 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE1 ALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKR
: .: ::.: : . : : .. ::: . :.
XP_016 AGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI
410 420 430 440 450 460
480 490 500
pF1KE1 SRAIHSSDEGEDQAGDEDEDDEWDD
XP_016 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP
470 480 490 500 510 520
>>XP_016857328 (OMIM: 606373,616193) PREDICTED: formin-2 (1159 aa)
initn: 313 init1: 313 opt: 458 Z-score: 178.1 bits: 43.7 E(85289): 0.0035
Smith-Waterman score: 503; 31.1% identity (48.5% similar) in 379 aa overlap (116-466:153-511)
90 100 110 120 130 140
pF1KE1 RLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGDDCQAGLNFADEDEAQAFRALVQEKI
: .:: : .: . .: :.. : : ..:
XP_016 LRTKIAELERQYPALDTEVASGHQGLENGVTASGDVCLEALRL-EEKEVRHHRILEAKSI
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE1 QKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPV---GPLSLGLAT--V
: ...: : ::. ::: : : : ..:: . . .:: .. .
XP_016 QTSPTEEGG---VLTLPPVD-------GLPGRPPCPPGAESGPQTKFCSEISLIVSPRRI
190 200 210 220 230
210 220 230 240 250
pF1KE1 DIQNPDITSSRYRGLPAPGPS---PADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNG
..: . .. . : : :: : . . :.. .:.. .: :. .:.
XP_016 SVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQP--PHSISTEFQTSHEHSVSSAFKNS
240 250 260 270 280
260 270 280 290 300 310
pF1KE1 FDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQE--MRRQEPLPP
.. . : : : ... .. : . . :. : .. : :::
XP_016 CNIPS-PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPST-AIPQPPPLQGTEMLPP
290 300 310 320 330 340
320 330 340 350 360 370
pF1KE1 PPPPSRGGNQLPRPPIVGGNKGRSGPLPPVP-LGIAPPPPTPRG---PPPPGRGGPPPPP
:::: :.. : ::. :.. ::::.: :: :::: : . :::: :. : :
XP_016 PPPPLPGAGIPPPPPLPGAGI---LPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLP
350 360 370 380 390 400
380 390 400 410
pF1KE1 PPATGRSGPLPPPPPGAGGPPMPP------PPPPP-------PPPPSSGNG-PAPPPLPP
:: : . : ::: :::: :: :: ::::: :::: : : : :::::
XP_016 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG
410 420 430 440 450 460
420 430 440 450 460 470
pF1KE1 ALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKR
: .: ::.: : . : : .. ::: . :.
XP_016 AGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI
470 480 490 500 510 520
480 490 500
pF1KE1 SRAIHSSDEGEDQAGDEDEDDEWDD
XP_016 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP
530 540 550 560 570 580
>>XP_011542539 (OMIM: 606373,616193) PREDICTED: formin-2 (1360 aa)
initn: 313 init1: 313 opt: 458 Z-score: 177.3 bits: 43.8 E(85289): 0.0039
Smith-Waterman score: 503; 31.1% identity (48.5% similar) in 379 aa overlap (116-466:720-1078)
90 100 110 120 130 140
pF1KE1 RLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGDDCQAGLNFADEDEAQAFRALVQEKI
: .:: : .: . .: :.. : : ..:
XP_011 LRTKIAELERQYPALDTEVASGHQGLENGVTASGDVCLEALRL-EEKEVRHHRILEAKSI
690 700 710 720 730 740
150 160 170 180 190 200
pF1KE1 QKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPV---GPLSLGLAT--V
: ...: : ::. ::: : : : ..:: . . .:: .. .
XP_011 QTSPTEEGG---VLTLPPVD-------GLPGRPPCPPGAESGPQTKFCSEISLIVSPRRI
750 760 770 780 790
210 220 230 240 250
pF1KE1 DIQNPDITSSRYRGLPAPGPS---PADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNG
..: . .. . : : :: : . . :.. .:.. .: :. .:.
XP_011 SVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQP--PHSISTEFQTSHEHSVSSAFKNS
800 810 820 830 840 850
260 270 280 290 300 310
pF1KE1 FDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQE--MRRQEPLPP
.. . : : : ... .. : . . :. : .. : :::
XP_011 CNIPS-PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPST-AIPQPPPLQGTEMLPP
860 870 880 890 900 910
320 330 340 350 360 370
pF1KE1 PPPPSRGGNQLPRPPIVGGNKGRSGPLPPVP-LGIAPPPPTPRG---PPPPGRGGPPPPP
:::: :.. : ::. :.. ::::.: :: :::: : . :::: :. : :
XP_011 PPPPLPGAGIPPPPPLPGAGI---LPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLP
920 930 940 950 960 970
380 390 400 410
pF1KE1 PPATGRSGPLPPPPPGAGGPPMPP------PPPPP-------PPPPSSGNG-PAPPPLPP
:: : . : ::: :::: :: :: ::::: :::: : : : :::::
XP_011 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG
980 990 1000 1010 1020 1030
420 430 440 450 460 470
pF1KE1 ALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKR
: .: ::.: : . : : .. ::: . :.
XP_011 AGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI
1040 1050 1060 1070 1080
480 490 500
pF1KE1 SRAIHSSDEGEDQAGDEDEDDEWDD
XP_011 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP
1090 1100 1110 1120 1130 1140
>>XP_016857327 (OMIM: 606373,616193) PREDICTED: formin-2 (1384 aa)
initn: 313 init1: 313 opt: 458 Z-score: 177.2 bits: 43.8 E(85289): 0.0039
Smith-Waterman score: 503; 31.1% identity (48.5% similar) in 379 aa overlap (116-466:720-1078)
90 100 110 120 130 140
pF1KE1 RLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGDDCQAGLNFADEDEAQAFRALVQEKI
: .:: : .: . .: :.. : : ..:
XP_016 LRTKIAELERQYPALDTEVASGHQGLENGVTASGDVCLEALRL-EEKEVRHHRILEAKSI
690 700 710 720 730 740
150 160 170 180 190 200
pF1KE1 QKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPV---GPLSLGLAT--V
: ...: : ::. ::: : : : ..:: . . .:: .. .
XP_016 QTSPTEEGG---VLTLPPVD-------GLPGRPPCPPGAESGPQTKFCSEISLIVSPRRI
750 760 770 780 790
210 220 230 240 250
pF1KE1 DIQNPDITSSRYRGLPAPGPS---PADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNG
..: . .. . : : :: : . . :.. .:.. .: :. .:.
XP_016 SVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQP--PHSISTEFQTSHEHSVSSAFKNS
800 810 820 830 840 850
260 270 280 290 300 310
pF1KE1 FDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQE--MRRQEPLPP
.. . : : : ... .. : . . :. : .. : :::
XP_016 CNIPS-PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPST-AIPQPPPLQGTEMLPP
860 870 880 890 900 910
320 330 340 350 360 370
pF1KE1 PPPPSRGGNQLPRPPIVGGNKGRSGPLPPVP-LGIAPPPPTPRG---PPPPGRGGPPPPP
:::: :.. : ::. :.. ::::.: :: :::: : . :::: :. : :
XP_016 PPPPLPGAGIPPPPPLPGAGI---LPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLP
920 930 940 950 960 970
380 390 400 410
pF1KE1 PPATGRSGPLPPPPPGAGGPPMPP------PPPPP-------PPPPSSGNG-PAPPPLPP
:: : . : ::: :::: :: :: ::::: :::: : : : :::::
XP_016 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG
980 990 1000 1010 1020 1030
420 430 440 450 460 470
pF1KE1 ALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKR
: .: ::.: : . : : .. ::: . :.
XP_016 AGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI
1040 1050 1060 1070 1080
480 490 500
pF1KE1 SRAIHSSDEGEDQAGDEDEDDEWDD
XP_016 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP
1090 1100 1110 1120 1130 1140
>>XP_016857326 (OMIM: 606373,616193) PREDICTED: formin-2 (1417 aa)
initn: 313 init1: 313 opt: 458 Z-score: 177.1 bits: 43.8 E(85289): 0.004
Smith-Waterman score: 503; 31.1% identity (48.5% similar) in 379 aa overlap (116-466:720-1078)
90 100 110 120 130 140
pF1KE1 RLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGDDCQAGLNFADEDEAQAFRALVQEKI
: .:: : .: . .: :.. : : ..:
XP_016 LRTKIAELERQYPALDTEVASGHQGLENGVTASGDVCLEALRL-EEKEVRHHRILEAKSI
690 700 710 720 730 740
150 160 170 180 190 200
pF1KE1 QKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPV---GPLSLGLAT--V
: ...: : ::. ::: : : : ..:: . . .:: .. .
XP_016 QTSPTEEGG---VLTLPPVD-------GLPGRPPCPPGAESGPQTKFCSEISLIVSPRRI
750 760 770 780 790
210 220 230 240 250
pF1KE1 DIQNPDITSSRYRGLPAPGPS---PADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNG
..: . .. . : : :: : . . :.. .:.. .: :. .:.
XP_016 SVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQP--PHSISTEFQTSHEHSVSSAFKNS
800 810 820 830 840 850
260 270 280 290 300 310
pF1KE1 FDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQE--MRRQEPLPP
.. . : : : ... .. : . . :. : .. : :::
XP_016 CNIPS-PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPST-AIPQPPPLQGTEMLPP
860 870 880 890 900 910
320 330 340 350 360 370
pF1KE1 PPPPSRGGNQLPRPPIVGGNKGRSGPLPPVP-LGIAPPPPTPRG---PPPPGRGGPPPPP
:::: :.. : ::. :.. ::::.: :: :::: : . :::: :. : :
XP_016 PPPPLPGAGIPPPPPLPGAGI---LPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLP
920 930 940 950 960 970
380 390 400 410
pF1KE1 PPATGRSGPLPPPPPGAGGPPMPP------PPPPP-------PPPPSSGNG-PAPPPLPP
:: : . : ::: :::: :: :: ::::: :::: : : : :::::
XP_016 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG
980 990 1000 1010 1020 1030
420 430 440 450 460 470
pF1KE1 ALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKR
: .: ::.: : . : : .. ::: . :.
XP_016 AGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI
1040 1050 1060 1070 1080
480 490 500
pF1KE1 SRAIHSSDEGEDQAGDEDEDDEWDD
XP_016 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP
1090 1100 1110 1120 1130 1140
502 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:39:49 2016 done: Mon Nov 7 01:39:50 2016
Total Scan time: 10.140 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]