Result of FASTA (ccds) for
pFN21AE1313
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1313, 218 aa
1>>>pF1KE1313 218 - 218 aa - 218 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2209+/-0.00065; mu= 14.9189+/- 0.039
mean_var=72.1779+/-14.135, 0's: 0 Z-trim(111.5): 25 B-trim: 62 in 1/50
Lambda= 0.150964
statistics sampled from 12447 (12466) to 12447 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.383), width: 16
Scan time: 2.340
The best scores are: opt bits E(32554)
CCDS2103.1 IL37 gene_id:27178|Hs108|chr2 ( 218) 1492 333.3 7e-92
CCDS2107.1 IL37 gene_id:27178|Hs108|chr2 ( 192) 1153 259.5 1.1e-69
CCDS2104.1 IL37 gene_id:27178|Hs108|chr2 ( 197) 1153 259.5 1.1e-69
CCDS2106.1 IL37 gene_id:27178|Hs108|chr2 ( 178) 907 205.9 1.4e-53
CCDS2105.1 IL37 gene_id:27178|Hs108|chr2 ( 157) 889 201.9 1.9e-52
CCDS2108.1 IL36G gene_id:56300|Hs108|chr2 ( 169) 313 76.5 1.1e-14
CCDS2110.1 IL36B gene_id:27177|Hs108|chr2 ( 157) 311 76.0 1.5e-14
CCDS42734.1 IL36A gene_id:27179|Hs108|chr2 ( 158) 305 74.7 3.6e-14
CCDS62992.1 IL36G gene_id:56300|Hs108|chr2 ( 134) 258 64.4 3.8e-11
>>CCDS2103.1 IL37 gene_id:27178|Hs108|chr2 (218 aa)
initn: 1492 init1: 1492 opt: 1492 Z-score: 1763.0 bits: 333.3 E(32554): 7e-92
Smith-Waterman score: 1492; 99.1% identity (99.5% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KE1 MSFVGENSGVKMGSEDWEKDEPQCCLEDPAVSPLEPGPSLPAMNFVHTSPKVKNLNPKKF
:::::::::::::::::::::::::::::: ::::::::::.::::::::::::::::::
CCDS21 MSFVGENSGVKMGSEDWEKDEPQCCLEDPAGSPLEPGPSLPTMNFVHTSPKVKNLNPKKF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 SIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS
130 140 150 160 170 180
190 200 210
pF1KE1 CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD
::::::::::::::::::::::::::::::::::::::
CCDS21 CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD
190 200 210
>>CCDS2107.1 IL37 gene_id:27178|Hs108|chr2 (192 aa)
initn: 1153 init1: 1153 opt: 1153 Z-score: 1364.8 bits: 259.5 E(32554): 1.1e-69
Smith-Waterman score: 1153; 100.0% identity (100.0% similar) in 169 aa overlap (50-218:24-192)
20 30 40 50 60 70
pF1KE1 DEPQCCLEDPAVSPLEPGPSLPAMNFVHTSPKVKNLNPKKFSIHDQDHKVLVLDSGNLIA
::::::::::::::::::::::::::::::
CCDS21 MSGCDRRETETKGKNSFKKRLRGPKVKNLNPKKFSIHDQDHKVLVLDSGNLIA
10 20 30 40 50
80 90 100 110 120 130
pF1KE1 VPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCLYCDKDKGQSHPSLQLKKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 VPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCLYCDKDKGQSHPSLQLKKEK
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE1 LMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPVGVTDKFENRKHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 LMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPVGVTDKFENRKHI
120 130 140 150 160 170
200 210
pF1KE1 EFSFQPVCKAEMSPSEVSD
:::::::::::::::::::
CCDS21 EFSFQPVCKAEMSPSEVSD
180 190
>>CCDS2104.1 IL37 gene_id:27178|Hs108|chr2 (197 aa)
initn: 1153 init1: 1153 opt: 1153 Z-score: 1364.6 bits: 259.5 E(32554): 1.1e-69
Smith-Waterman score: 1300; 89.9% identity (90.4% similar) in 218 aa overlap (1-218:1-197)
10 20 30 40 50 60
pF1KE1 MSFVGENSGVKMGSEDWEKDEPQCCLEDPAVSPLEPGPSLPAMNFVHTSPKVKNLNPKKF
::::::::::::::::::::::::::: .:::::::::::
CCDS21 MSFVGENSGVKMGSEDWEKDEPQCCLE---------------------GPKVKNLNPKKF
10 20 30
70 80 90 100 110 120
pF1KE1 SIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 SIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS
100 110 120 130 140 150
190 200 210
pF1KE1 CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD
::::::::::::::::::::::::::::::::::::::
CCDS21 CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD
160 170 180 190
>>CCDS2106.1 IL37 gene_id:27178|Hs108|chr2 (178 aa)
initn: 907 init1: 907 opt: 907 Z-score: 1075.7 bits: 205.9 E(32554): 1.4e-53
Smith-Waterman score: 1128; 80.3% identity (81.2% similar) in 218 aa overlap (1-218:1-178)
10 20 30 40 50 60
pF1KE1 MSFVGENSGVKMGSEDWEKDEPQCCLEDPAVSPLEPGPSLPAMNFVHTSPKVKNLNPKKF
:::::::::::::::::::::::::::::: ::::::::::.::::::
CCDS21 MSFVGENSGVKMGSEDWEKDEPQCCLEDPAGSPLEPGPSLPTMNFVHT------------
10 20 30 40
70 80 90 100 110 120
pF1KE1 SIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCL
.:::::::::::::::::::::::::::::::
CCDS21 ----------------------------KIFFALASSLSSASAEKGSPILLGVSKGEFCL
50 60 70 80
130 140 150 160 170 180
pF1KE1 YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS
90 100 110 120 130 140
190 200 210
pF1KE1 CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD
::::::::::::::::::::::::::::::::::::::
CCDS21 CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD
150 160 170
>>CCDS2105.1 IL37 gene_id:27178|Hs108|chr2 (157 aa)
initn: 889 init1: 889 opt: 889 Z-score: 1055.3 bits: 201.9 E(32554): 1.9e-52
Smith-Waterman score: 956; 72.0% identity (72.0% similar) in 218 aa overlap (1-218:1-157)
10 20 30 40 50 60
pF1KE1 MSFVGENSGVKMGSEDWEKDEPQCCLEDPAVSPLEPGPSLPAMNFVHTSPKVKNLNPKKF
:::::::::::::::::::::::::::
CCDS21 MSFVGENSGVKMGSEDWEKDEPQCCLE---------------------------------
10 20
70 80 90 100 110 120
pF1KE1 SIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCL
::::::::::::::::::::::::::::::::
CCDS21 ----------------------------EIFFALASSLSSASAEKGSPILLGVSKGEFCL
30 40 50
130 140 150 160 170 180
pF1KE1 YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS
60 70 80 90 100 110
190 200 210
pF1KE1 CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD
::::::::::::::::::::::::::::::::::::::
CCDS21 CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD
120 130 140 150
>>CCDS2108.1 IL36G gene_id:56300|Hs108|chr2 (169 aa)
initn: 264 init1: 120 opt: 313 Z-score: 376.8 bits: 76.5 E(32554): 1.1e-14
Smith-Waterman score: 313; 36.3% identity (67.8% similar) in 146 aa overlap (57-201:22-163)
30 40 50 60 70 80
pF1KE1 EDPAVSPLEPGPSLPAMNFVHTSPKVKNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYI
: .:.: ...: .:.. ::.::: .. .
CCDS21 MRGTPGDADGGGRAVYQSMCKPITGTINDLNQQVWTLQGQNLVAVPRSDSV
10 20 30 40 50
90 100 110 120 130 140
pF1KE1 RPEIFFALASSLSSASAE-KGSPILLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLAA
: ... . : . .:.:: ::... :.::::.: : :.::::..:.: : .
CCDS21 TPVTVAVITCKYPEALEQGRGDPIYLGIQNPEMCLYCEKVGEQ--PTLQLKEQKIMDLYG
60 70 80 90 100
150 160 170 180 190 200
pF1KE1 QKESARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQP
: : .. ::.::::..: . :::.: : ::: .: ..:. .:... . . :
CCDS21 QPEPVK-PFLFYRAKTGRTSTLESVAFPDWFIASSKR-DQPIILTSELGKSYNTAFELNI
110 120 130 140 150 160
210
pF1KE1 VCKAEMSPSEVSD
CCDS21 ND
>>CCDS2110.1 IL36B gene_id:27177|Hs108|chr2 (157 aa)
initn: 308 init1: 138 opt: 311 Z-score: 374.9 bits: 76.0 E(32554): 1.5e-14
Smith-Waterman score: 311; 32.1% identity (71.1% similar) in 159 aa overlap (49-206:2-156)
20 30 40 50 60 70
pF1KE1 KDEPQCCLEDPAVSPLEPGPSLPAMNFVHTSPKVKNLNPKKFSIHDQDHKVLVLDSGNLI
.:. .. ::...:.:. . : ::....::
CCDS21 MNPQ-REAAPKSYAIRDSRQMVWVLSGNSLI
10 20 30
80 90 100 110 120 130
pF1KE1 AVPDKNYIRPEIFFALASSLSSAS-AEKGSPILLGVSKGEFCLYCDKDKGQSHPSLQLKK
:.: . :.: . .: . : :::. . ::.. ..::.: . .:. :.::::.
CCDS21 AAPLSRSIKPVTLHLIACRDTEFSDKEKGNMVYLGIKGKDLCLFCAEIQGK--PTLQLKE
40 50 60 70 80
140 150 160 170 180 190
pF1KE1 EKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPVGVTDKFENRK
...: : ..:. :..::.:.. . :: ....:...::::: :: . ..:. .: . .
CCDS21 KNIMDLYVEKK-AQKPFLFFHNKEGSTSVFQSVSYPGWFIATSTTSGQPIFLTKERGITN
90 100 110 120 130 140
200 210
pF1KE1 HIEFSFQPVCKAEMSPSEVSD
. .: .. :
CCDS21 NTNFYLDSVE
150
>>CCDS42734.1 IL36A gene_id:27179|Hs108|chr2 (158 aa)
initn: 271 init1: 105 opt: 305 Z-score: 367.8 bits: 74.7 E(32554): 3.6e-14
Smith-Waterman score: 305; 37.6% identity (67.1% similar) in 149 aa overlap (57-203:10-154)
30 40 50 60 70 80
pF1KE1 EDPAVSPLEPGPSLPAMNFVHTSPKVKNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYI
:.. ::.: .:.: ::.. .::::: :. .
CCDS42 MEKALKIDTPQQGSIQDINHRVWVLQDQTLIAVPRKDRM
10 20 30
90 100 110 120 130 140
pF1KE1 RPEIFFALASSLSSASAEK--GSPILLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLA
: . .:: : . :: :.:: ::.. ..::.: : : :.::::.. .: :
CCDS42 SP-VTIALISCRHVETLEKDRGNPIYLGLNGLNLCLMCAKVGDQ--PTLQLKEKDIMDLY
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 AQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQ
: : .. :.::..: : . .::.: ::::: .: . . :. .:... . . .:..
CCDS42 NQPEPVKS-FLFYHSQSGRNSTFESVAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLT
100 110 120 130 140 150
210
pF1KE1 PVCKAEMSPSEVSD
CCDS42 MLF
>>CCDS62992.1 IL36G gene_id:56300|Hs108|chr2 (134 aa)
initn: 231 init1: 120 opt: 258 Z-score: 313.5 bits: 64.4 E(32554): 3.8e-11
Smith-Waterman score: 258; 42.3% identity (72.2% similar) in 97 aa overlap (105-201:36-128)
80 90 100 110 120 130
pF1KE1 GNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCLYCDKDKGQSHPSLQ
.:.:: ::... :.::::.: : :.::
CCDS62 GDADGGGRAVYQSITVAVITCKYPEALEQGRGDPIYLGIQNPEMCLYCEKVGEQ--PTLQ
10 20 30 40 50 60
140 150 160 170 180 190
pF1KE1 LKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPVGVTDKFE
::..:.: : .: : .. ::.::::..: . :::.: : ::: .: ..:. .:...
CCDS62 LKEQKIMDLYGQPEPVK-PFLFYRAKTGRTSTLESVAFPDWFIASSKR-DQPIILTSELG
70 80 90 100 110 120
200 210
pF1KE1 NRKHIEFSFQPVCKAEMSPSEVSD
. . :
CCDS62 KSYNTAFELNIND
130
218 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:45:01 2016 done: Mon Nov 7 00:45:02 2016
Total Scan time: 2.340 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]