FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1309, 357 aa
  1>>>pF1KE1309 357 - 357 aa - 357 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 13.2003+/-0.00051; mu= -17.4291+/- 0.032
 mean_var=506.3164+/-105.159, 0's: 0 Z-trim(121.9): 7  B-trim: 41 in 1/58
 Lambda= 0.056998
 statistics sampled from 39141 (39150) to 39141 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.459), width:  16
 Scan time:  9.410

The best scores are:                                      opt bits E(85289)
NP_003745 (OMIM: 603914) eukaryotic translation in ( 357) 2319 204.7 2.7e-52
NP_002802 (OMIM: 157970) 26S proteasome non-ATPase ( 324)  404 47.2 6.3e-05
NP_006824 (OMIM: 614729) COP9 signalosome complex  ( 327)  354 43.0  0.0011


>>NP_003745 (OMIM: 603914) eukaryotic translation initia  (357 aa)
 initn: 2319 init1: 2319 opt: 2319  Z-score: 1059.9  bits: 204.7 E(85289): 2.7e-52
Smith-Waterman score: 2319; 100.0% identity (100.0% similar) in 357 aa overlap (1-357:1-357)

               10        20        30        40        50        60
pF1KE1 MATPAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MATPAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 QTPASAQAPAQTPAPALPGPALPGPFPGGRVVRLHPVILASIVDSYERRNEGAARVIGTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QTPASAQAPAQTPAPALPGPALPGPFPGGRVVRLHPVILASIVDSYERRNEGAARVIGTL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 LGTVDKHSVEVTNCFSVPHNESEDEVAVDMEFAKNMYELHKKVSPNELILGWYATGHDIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LGTVDKHSVEVTNCFSVPHNESEDEVAVDMEFAKNMYELHKKVSPNELILGWYATGHDIT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 EHSVLIHEYYSREAPNPIHLTVDTSLQNGRMSIKAYVSTLMGVPGRTMGVMFTPLTVKYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EHSVLIHEYYSREAPNPIHLTVDTSLQNGRMSIKAYVSTLMGVPGRTMGVMFTPLTVKYA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 YYDTERIGVDLIMKTCFSPNRVIGLSSDLQQVGGASARIQDALSTVLQYAEDVLSGKVSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YYDTERIGVDLIMKTCFSPNRVIGLSSDLQQVGGASARIQDALSTVLQYAEDVLSGKVSA
              250       260       270       280       290       300

              310       320       330       340       350       
pF1KE1 DNTVGRFLMSLVNQVPKIVPDDFETMLNSNINDLLMVTYLANLTQSQIALNEKLVNL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DNTVGRFLMSLVNQVPKIVPDDFETMLNSNINDLLMVTYLANLTQSQIALNEKLVNL
              310       320       330       340       350       

>>NP_002802 (OMIM: 157970) 26S proteasome non-ATPase reg  (324 aa)
 initn: 371 init1: 187 opt: 404  Z-score: 209.4  bits: 47.2 E(85289): 6.3e-05
Smith-Waterman score: 404; 29.0% identity (64.7% similar) in 272 aa overlap (92-356:9-277)

              70        80        90       100       110           
pF1KE1 TPASAQAPAQTPAPALPGPALPGPFPGGRVVRLHPVILASIVDSYERRNE--GAARVIGT
                                     : .::..: :.:: ..: ..  .  ::.:.
NP_002                       MPELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGV
                                     10        20        30        

     120       130       140          150       160       170      
pF1KE1 LLGTVDKHSVEVTNCFSVPHNESEDEVAV---DMEFAKNMYELHKKVSPNELILGWYATG
       :::. .:. ..:.: :.:: .:.. . .:   : .. .::: . :::.  : :.::: ::
NP_002 LLGSWQKKVLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTG
       40        50        60        70        80        90        

        180       190       200       210       220        230     
pF1KE1 HDITEHSVLIHEYYSREAPNPIHLTVDTSLQNGRMSIKAYVSTL-MGVPGRTMGVMFTPL
         . .... :.: ..:  :: . . .:.. ..  .  .::.:.  .   :   .  :  .
NP_002 PKLHKNDIAINELMKRYCPNSVLVIIDVKPKDLGLPTEAYISVEEVHDDGTPTSKTFEHV
      100       110       120       130       140       150        

         240       250       260        270       280       290    
pF1KE1 TVKYAYYDTERIGVDLIMKTCFSPNRVIGLSSDL-QQVGGASARIQDALSTVLQYAEDVL
       : . .  ..:..::. ...  .. . :  ::. . .:: : .. ... :  . .: : : 
NP_002 TSEIGAEEAEEVGVEHLLRD-IKDTTVGTLSQRITNQVHGLKG-LNSKLLDIRSYLEKVA
      160       170        180       190       200        210      

          300       310       320       330       340       350    
pF1KE1 SGKVSADNTVGRFLMSLVNQVPKIVPDDFETMLNSNINDLLMVTYLANLTQSQIALNEKL
       .::.  .. .   :... : .: .  ..:   .  . :: ..:.:::.: .: .::.. :
NP_002 TGKLPINHQIIYQLQDVFNLLPDVSLQEFVKAFYLKTNDQMVVVYLASLIRSVVALHN-L
        220       230       240       250       260       270      

                                                        
pF1KE1 VNL                                              
       .:                                               
NP_002 INNKIANRDAEKKEGQEKEESKKDRKEDKEKDKDKEKSDVKKEEKKEKK
         280       290       300       310       320    

>>NP_006824 (OMIM: 614729) COP9 signalosome complex subu  (327 aa)
 initn: 296 init1: 131 opt: 354  Z-score: 187.2  bits: 43.0 E(85289): 0.0011
Smith-Waterman score: 354; 25.7% identity (59.8% similar) in 311 aa overlap (50-356:2-307)

      20        30        40        50        60        70         
pF1KE1 AAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQTPASAQAPAQTPAPALPG
                                     ::::::.:: . : .:.    .. : ..:.
NP_006                              MAAAAAAAAATNGTGGSSGM--EVDAAVVPS
                                            10        20           

      80        90       100         110        120       130      
pF1KE1 PALPGPFPGGRVVRLHPVILASIVDSY--ERRNEG-AARVIGTLLGTVDKHSVEVTNCFS
           :   :.  : :::... .: : .   : .::  ..:::.:.:  . ...:: : : 
NP_006 VMACG-VTGSVSVALHPLVILNISDHWIRMRSQEGRPVQVIGALIGKQEGRNIEVMNSFE
      30         40        50        60        70        80        

        140       150       160       170       180       190      
pF1KE1 VPHNESEDEVAVDMEFAKNMYELHKKVSPNELILGWYATGHDITEHSVLIHEYYSREAPN
       .  .  :... .: :.  .  :  :.:  .  .::::.::      .. .:.   .   .
NP_006 LLSHTVEEKIIIDKEYYYTKEEQFKQVFKELEFLGWYTTGGPPDPSDIHVHKQVCEIIES
       90       100       110       120       130       140        

        200       210       220       230       240       250      
pF1KE1 PIHLTVDTSLQNGRMSIKAYVSTLMGVPGRTMGVMFTPLTVKYAYYDTERIGVDLIMK-T
       :. : ..   ..  . .... :..  . :..  ..:. ::   :  ..:::::: . . :
NP_006 PLFLKLNPMTKHTDLPVSVFESVIDIINGEAT-MLFAELTYTLATEEAERIGVDHVARMT
      150       160       170       180        190       200       

         260       270       280       290       300       310     
pF1KE1 CFSPNRVIGLSSDLQQVGGASARIQDALSTVLQYAEDVLSGKVSADNTVGRFLMSLVNQV
         . ..   ..  :    .:   ... .. .:.:..   .:.:  .. . :  ..: . .
NP_006 ATGSGENSTVAEHLIAQHSAIKMLHSRVKLILEYVKASEAGEVPFNHEILREAYALCHCL
       210       220       230       240       250       260       

         320       330       340       350                         
pF1KE1 PKIVPDDFETMLNSNINDLLMVTYLANLTQSQIALNEKLVNL                  
       : .  : :.: . .. ::. ...::...:..  ..:. .::                   
NP_006 PVLSTDKFKTDFYDQCNDVGLMAYLGTITKTCNTMNQ-FVNKFNVLYDRQGIGRRMRGLF
       270       280       290       300        310       320      

NP_006 F
        




357 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 03:05:03 2016 done: Mon Nov  7 03:05:05 2016
 Total Scan time:  9.410 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]