Result of FASTA (omim) for
pFN21AE1302
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1302, 145 aa
1>>>pF1KE1302 145 - 145 aa - 145 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9145+/-0.000306; mu= 14.5151+/- 0.019
mean_var=78.5574+/-15.528, 0's: 0 Z-trim(119.1): 40 B-trim: 60 in 1/52
Lambda= 0.144704
statistics sampled from 32785 (32828) to 32785 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.385), width: 16
Scan time: 4.990
The best scores are: opt bits E(85289)
NP_036532 (OMIM: 605630) group IID secretory phosp ( 145) 1110 240.2 9.1e-64
NP_001155200 (OMIM: 172411) phospholipase A2, memb ( 144) 520 117.0 1.1e-26
NP_001155201 (OMIM: 172411) phospholipase A2, memb ( 144) 520 117.0 1.1e-26
NP_001155199 (OMIM: 172411) phospholipase A2, memb ( 144) 520 117.0 1.1e-26
NP_000291 (OMIM: 172411) phospholipase A2, membran ( 144) 520 117.0 1.1e-26
XP_011539893 (OMIM: 228980,601192) PREDICTED: calc ( 138) 473 107.2 9.4e-24
XP_011539891 (OMIM: 228980,601192) PREDICTED: calc ( 138) 473 107.2 9.4e-24
XP_011539889 (OMIM: 228980,601192) PREDICTED: calc ( 138) 473 107.2 9.4e-24
XP_005245950 (OMIM: 228980,601192) PREDICTED: calc ( 138) 473 107.2 9.4e-24
XP_011539894 (OMIM: 228980,601192) PREDICTED: calc ( 138) 473 107.2 9.4e-24
XP_011539890 (OMIM: 228980,601192) PREDICTED: calc ( 138) 473 107.2 9.4e-24
XP_011539892 (OMIM: 228980,601192) PREDICTED: calc ( 138) 473 107.2 9.4e-24
NP_000920 (OMIM: 228980,601192) calcium-dependent ( 138) 473 107.2 9.4e-24
NP_073730 (OMIM: 616793) group IIF secretory phosp ( 211) 475 107.8 9.5e-24
XP_011540258 (OMIM: 616793) PREDICTED: group IIF s ( 211) 475 107.8 9.5e-24
XP_011539888 (OMIM: 228980,601192) PREDICTED: calc ( 169) 473 107.2 1.1e-23
XP_005245948 (OMIM: 228980,601192) PREDICTED: calc ( 169) 473 107.2 1.1e-23
XP_005245949 (OMIM: 228980,601192) PREDICTED: calc ( 169) 473 107.2 1.1e-23
NP_001258743 (OMIM: 605630) group IID secretory ph ( 62) 432 98.3 2e-21
NP_003552 (OMIM: 603603) group 10 secretory phosph ( 165) 383 88.4 4.8e-18
XP_011540257 (OMIM: 616793) PREDICTED: group IIF s ( 219) 351 81.9 6.1e-16
NP_000919 (OMIM: 172410) phospholipase A2 precurso ( 148) 325 76.3 2e-14
XP_011521000 (OMIM: 603603) PREDICTED: group 10 se ( 120) 277 66.2 1.8e-11
XP_011520999 (OMIM: 603603) PREDICTED: group 10 se ( 124) 277 66.2 1.8e-11
XP_011520998 (OMIM: 603603) PREDICTED: group 10 se ( 131) 277 66.2 1.9e-11
XP_011520997 (OMIM: 603603) PREDICTED: group 10 se ( 133) 277 66.2 1.9e-11
NP_001073868 (OMIM: 601658) otoconin-90 precursor ( 477) 271 65.5 1.1e-10
>>NP_036532 (OMIM: 605630) group IID secretory phospholi (145 aa)
initn: 1110 init1: 1110 opt: 1110 Z-score: 1265.8 bits: 240.2 E(85289): 9.1e-64
Smith-Waterman score: 1110; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:1-145)
10 20 30 40 50 60
pF1KE1 MELALLCGLVVMAGVIPIQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQPKDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MELALLCGLVVMAGVIPIQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQPKDAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVAFCLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVAFCLK
70 80 90 100 110 120
130 140
pF1KE1 RNLDTYQKRLRFYWRPHCRGQTPGC
:::::::::::::::::::::::::
NP_036 RNLDTYQKRLRFYWRPHCRGQTPGC
130 140
>>NP_001155200 (OMIM: 172411) phospholipase A2, membrane (144 aa)
initn: 495 init1: 329 opt: 520 Z-score: 600.2 bits: 117.0 E(85289): 1.1e-26
Smith-Waterman score: 520; 46.9% identity (73.1% similar) in 145 aa overlap (1-145:1-144)
10 20 30 40 50 60
pF1KE1 MELALLCGLVVMAGVIPIQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQPKDAT
:. :: ..... :.. .:...:...:.: .::: ::: ::::::.::::.:::::
NP_001 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVAFCLK
: :: :::::: .:. .::. :... : . : :. . : :..::: ::: .: :.
NP_001 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDS-CRSQLCECDKAAATCFA
70 80 90 100 110
130 140
pF1KE1 RNLDTYQKRLRFYWRPHCRGQTPGC
:: ::.:. ..: ::::.:: :
NP_001 RNKTTYNKKYQYYSNKHCRGSTPRC
120 130 140
>>NP_001155201 (OMIM: 172411) phospholipase A2, membrane (144 aa)
initn: 495 init1: 329 opt: 520 Z-score: 600.2 bits: 117.0 E(85289): 1.1e-26
Smith-Waterman score: 520; 46.9% identity (73.1% similar) in 145 aa overlap (1-145:1-144)
10 20 30 40 50 60
pF1KE1 MELALLCGLVVMAGVIPIQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQPKDAT
:. :: ..... :.. .:...:...:.: .::: ::: ::::::.::::.:::::
NP_001 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVAFCLK
: :: :::::: .:. .::. :... : . : :. . : :..::: ::: .: :.
NP_001 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDS-CRSQLCECDKAAATCFA
70 80 90 100 110
130 140
pF1KE1 RNLDTYQKRLRFYWRPHCRGQTPGC
:: ::.:. ..: ::::.:: :
NP_001 RNKTTYNKKYQYYSNKHCRGSTPRC
120 130 140
>>NP_001155199 (OMIM: 172411) phospholipase A2, membrane (144 aa)
initn: 495 init1: 329 opt: 520 Z-score: 600.2 bits: 117.0 E(85289): 1.1e-26
Smith-Waterman score: 520; 46.9% identity (73.1% similar) in 145 aa overlap (1-145:1-144)
10 20 30 40 50 60
pF1KE1 MELALLCGLVVMAGVIPIQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQPKDAT
:. :: ..... :.. .:...:...:.: .::: ::: ::::::.::::.:::::
NP_001 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVAFCLK
: :: :::::: .:. .::. :... : . : :. . : :..::: ::: .: :.
NP_001 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDS-CRSQLCECDKAAATCFA
70 80 90 100 110
130 140
pF1KE1 RNLDTYQKRLRFYWRPHCRGQTPGC
:: ::.:. ..: ::::.:: :
NP_001 RNKTTYNKKYQYYSNKHCRGSTPRC
120 130 140
>>NP_000291 (OMIM: 172411) phospholipase A2, membrane as (144 aa)
initn: 495 init1: 329 opt: 520 Z-score: 600.2 bits: 117.0 E(85289): 1.1e-26
Smith-Waterman score: 520; 46.9% identity (73.1% similar) in 145 aa overlap (1-145:1-144)
10 20 30 40 50 60
pF1KE1 MELALLCGLVVMAGVIPIQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQPKDAT
:. :: ..... :.. .:...:...:.: .::: ::: ::::::.::::.:::::
NP_000 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVAFCLK
: :: :::::: .:. .::. :... : . : :. . : :..::: ::: .: :.
NP_000 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDS-CRSQLCECDKAAATCFA
70 80 90 100 110
130 140
pF1KE1 RNLDTYQKRLRFYWRPHCRGQTPGC
:: ::.:. ..: ::::.:: :
NP_000 RNKTTYNKKYQYYSNKHCRGSTPRC
120 130 140
>>XP_011539893 (OMIM: 228980,601192) PREDICTED: calcium- (138 aa)
initn: 463 init1: 343 opt: 473 Z-score: 547.4 bits: 107.2 E(85289): 9.4e-24
Smith-Waterman score: 473; 45.3% identity (75.0% similar) in 128 aa overlap (12-138:11-137)
10 20 30 40 50
pF1KE1 MELALLCGLVVMAGVIP-IQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQPKDA
.: .: .:::.:.:..:...:::: . .: :::.:: :::: :::.
XP_011 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDG
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 TDWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVAFCL
::::: .:: :: .:. .::.: . :.: :. : . : . : .:. .:::::.....::
XP_011 TDWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTC-EPGPFCHVNLCACDRKLVYCL
60 70 80 90 100 110
120 130 140
pF1KE1 KRNLDTYQKRLRFYWRPHCRGQTPGC
:::: .:. . ... :
XP_011 KRNLRSYNPQYQYFPNILCS
120 130
>>XP_011539891 (OMIM: 228980,601192) PREDICTED: calcium- (138 aa)
initn: 463 init1: 343 opt: 473 Z-score: 547.4 bits: 107.2 E(85289): 9.4e-24
Smith-Waterman score: 473; 45.3% identity (75.0% similar) in 128 aa overlap (12-138:11-137)
10 20 30 40 50
pF1KE1 MELALLCGLVVMAGVIP-IQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQPKDA
.: .: .:::.:.:..:...:::: . .: :::.:: :::: :::.
XP_011 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDG
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 TDWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVAFCL
::::: .:: :: .:. .::.: . :.: :. : . : . : .:. .:::::.....::
XP_011 TDWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTC-EPGPFCHVNLCACDRKLVYCL
60 70 80 90 100 110
120 130 140
pF1KE1 KRNLDTYQKRLRFYWRPHCRGQTPGC
:::: .:. . ... :
XP_011 KRNLRSYNPQYQYFPNILCS
120 130
>>XP_011539889 (OMIM: 228980,601192) PREDICTED: calcium- (138 aa)
initn: 463 init1: 343 opt: 473 Z-score: 547.4 bits: 107.2 E(85289): 9.4e-24
Smith-Waterman score: 473; 45.3% identity (75.0% similar) in 128 aa overlap (12-138:11-137)
10 20 30 40 50
pF1KE1 MELALLCGLVVMAGVIP-IQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQPKDA
.: .: .:::.:.:..:...:::: . .: :::.:: :::: :::.
XP_011 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDG
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 TDWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVAFCL
::::: .:: :: .:. .::.: . :.: :. : . : . : .:. .:::::.....::
XP_011 TDWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTC-EPGPFCHVNLCACDRKLVYCL
60 70 80 90 100 110
120 130 140
pF1KE1 KRNLDTYQKRLRFYWRPHCRGQTPGC
:::: .:. . ... :
XP_011 KRNLRSYNPQYQYFPNILCS
120 130
>>XP_005245950 (OMIM: 228980,601192) PREDICTED: calcium- (138 aa)
initn: 463 init1: 343 opt: 473 Z-score: 547.4 bits: 107.2 E(85289): 9.4e-24
Smith-Waterman score: 473; 45.3% identity (75.0% similar) in 128 aa overlap (12-138:11-137)
10 20 30 40 50
pF1KE1 MELALLCGLVVMAGVIP-IQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQPKDA
.: .: .:::.:.:..:...:::: . .: :::.:: :::: :::.
XP_005 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDG
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 TDWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVAFCL
::::: .:: :: .:. .::.: . :.: :. : . : . : .:. .:::::.....::
XP_005 TDWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTC-EPGPFCHVNLCACDRKLVYCL
60 70 80 90 100 110
120 130 140
pF1KE1 KRNLDTYQKRLRFYWRPHCRGQTPGC
:::: .:. . ... :
XP_005 KRNLRSYNPQYQYFPNILCS
120 130
>>XP_011539894 (OMIM: 228980,601192) PREDICTED: calcium- (138 aa)
initn: 463 init1: 343 opt: 473 Z-score: 547.4 bits: 107.2 E(85289): 9.4e-24
Smith-Waterman score: 473; 45.3% identity (75.0% similar) in 128 aa overlap (12-138:11-137)
10 20 30 40 50
pF1KE1 MELALLCGLVVMAGVIP-IQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQPKDA
.: .: .:::.:.:..:...:::: . .: :::.:: :::: :::.
XP_011 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDG
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 TDWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVAFCL
::::: .:: :: .:. .::.: . :.: :. : . : . : .:. .:::::.....::
XP_011 TDWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTC-EPGPFCHVNLCACDRKLVYCL
60 70 80 90 100 110
120 130 140
pF1KE1 KRNLDTYQKRLRFYWRPHCRGQTPGC
:::: .:. . ... :
XP_011 KRNLRSYNPQYQYFPNILCS
120 130
145 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:40:57 2016 done: Mon Nov 7 03:40:58 2016
Total Scan time: 4.990 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]