Result of FASTA (omim) for
pFN21AE1274
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1274, 711 aa
1>>>pF1KE1274 711 - 711 aa - 711 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3575+/-0.000471; mu= 19.2787+/- 0.029
mean_var=62.3591+/-13.153, 0's: 0 Z-trim(108.3): 26 B-trim: 1159 in 2/48
Lambda= 0.162414
statistics sampled from 16391 (16405) to 16391 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.555), E-opt: 0.2 (0.192), width: 16
Scan time: 9.570
The best scores are: opt bits E(85289)
XP_005273614 (OMIM: 611353) PREDICTED: integrator ( 711) 4751 1122.6 0
NP_060612 (OMIM: 611353) integrator complex subuni ( 710) 4732 1118.2 0
XP_005273612 (OMIM: 611353) PREDICTED: integrator ( 737) 4422 1045.5 0
XP_016869095 (OMIM: 611353) PREDICTED: integrator ( 697) 4419 1044.8 0
XP_005273613 (OMIM: 611353) PREDICTED: integrator ( 736) 4403 1041.1 0
XP_016869096 (OMIM: 611353) PREDICTED: integrator ( 662) 4212 996.3 0
XP_006716418 (OMIM: 611353) PREDICTED: integrator ( 624) 3664 867.9 0
XP_016869097 (OMIM: 611353) PREDICTED: integrator ( 357) 1889 451.9 2e-126
XP_016869098 (OMIM: 611353) PREDICTED: integrator ( 357) 1889 451.9 2e-126
>>XP_005273614 (OMIM: 611353) PREDICTED: integrator comp (711 aa)
initn: 4751 init1: 4751 opt: 4751 Z-score: 6010.3 bits: 1122.6 E(85289): 0
Smith-Waterman score: 4751; 100.0% identity (100.0% similar) in 711 aa overlap (1-711:1-711)
10 20 30 40 50 60
pF1KE1 MSAQGDCEFLVQRARELVPQDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTATAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSAQGDCEFLVQRARELVPQDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTATAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RLLYDMFVNFPDQPVVWREISIITSALRNDSQDKQTQFLRSLFETLPGRVQCEMLLKVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLLYDMFVNFPDQPVVWREISIITSALRNDSQDKQTQFLRSLFETLPGRVQCEMLLKVTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QCFNTLERSEMLLLLLRRFPETVVQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QCFNTLERSEMLLLLLRRFPETVVQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LIINNHDVRLPANLLYKYLNKAAEFYINYVTRSTQIENQHQGAQDTSDLMSPSKRSSQKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIINNHDVRLPANLLYKYLNKAAEFYINYVTRSTQIENQHQGAQDTSDLMSPSKRSSQKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 IIEGLTEKSSQIVDPWERLFKILNVVGMRCEWQMDKGRRSYGDILHRMKDLCRYMNNFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IIEGLTEKSSQIVDPWERLFKILNVVGMRCEWQMDKGRRSYGDILHRMKDLCRYMNNFDS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EAHAKYKNQVVYSTMLVFFKNAFQYVNSIQPSLFQGPNAPSQVPLVLLEDVSNVYGDVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAHAKYKNQVVYSTMLVFFKNAFQYVNSIQPSLFQGPNAPSQVPLVLLEDVSNVYGDVEI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 DRNKHIHKKRKLAEGREKTMQSSDDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRNKHIHKKRKLAEGREKTMQSSDDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARES
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 WELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLHHLAALQGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLHHLAALQGSI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 SQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 VKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 GENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIK
610 620 630 640 650 660
670 680 690 700 710
pF1KE1 HHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLT
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLT
670 680 690 700 710
>>NP_060612 (OMIM: 611353) integrator complex subunit 10 (710 aa)
initn: 2543 init1: 2543 opt: 4732 Z-score: 5986.2 bits: 1118.2 E(85289): 0
Smith-Waterman score: 4732; 99.9% identity (99.9% similar) in 711 aa overlap (1-711:1-710)
10 20 30 40 50 60
pF1KE1 MSAQGDCEFLVQRARELVPQDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTATAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MSAQGDCEFLVQRARELVPQDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTATAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RLLYDMFVNFPDQPVVWREISIITSALRNDSQDKQTQFLRSLFETLPGRVQCEMLLKVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RLLYDMFVNFPDQPVVWREISIITSALRNDSQDKQTQFLRSLFETLPGRVQCEMLLKVTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QCFNTLERSEMLLLLLRRFPETVVQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QCFNTLERSEMLLLLLRRFPETVVQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LIINNHDVRLPANLLYKYLNKAAEFYINYVTRSTQIENQHQGAQDTSDLMSPSKRSSQKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LIINNHDVRLPANLLYKYLNKAAEFYINYVTRSTQIENQHQGAQDTSDLMSPSKRSSQKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 IIEGLTEKSSQIVDPWERLFKILNVVGMRCEWQMDKGRRSYGDILHRMKDLCRYMNNFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IIEGLTEKSSQIVDPWERLFKILNVVGMRCEWQMDKGRRSYGDILHRMKDLCRYMNNFDS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EAHAKYKNQVVYSTMLVFFKNAFQYVNSIQPSLFQGPNAPSQVPLVLLEDVSNVYGDVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EAHAKYKNQVVYSTMLVFFKNAFQYVNSIQPSLFQGPNAPSQVPLVLLEDVSNVYGDVEI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 DRNKHIHKKRKLAEGREKTMQSSDDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARES
:::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
NP_060 DRNKHIHKKRKLAEGREKTM-SSDDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARES
370 380 390 400 410
430 440 450 460 470 480
pF1KE1 WELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLHHLAALQGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 WELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLHHLAALQGSI
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE1 SQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSK
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE1 VKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPR
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE1 GENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIK
600 610 620 630 640 650
670 680 690 700 710
pF1KE1 HHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLT
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 HHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLT
660 670 680 690 700 710
>>XP_005273612 (OMIM: 611353) PREDICTED: integrator comp (737 aa)
initn: 4418 init1: 4418 opt: 4422 Z-score: 5593.4 bits: 1045.5 E(85289): 0
Smith-Waterman score: 4689; 96.5% identity (96.5% similar) in 737 aa overlap (1-711:1-737)
10 20 30 40 50 60
pF1KE1 MSAQGDCEFLVQRARELVPQDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTATAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSAQGDCEFLVQRARELVPQDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTATAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RLLYDMFVNFPDQPVVWREISIITSALRNDSQDKQTQFLRSLFETLPGRVQCEMLLKVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLLYDMFVNFPDQPVVWREISIITSALRNDSQDKQTQFLRSLFETLPGRVQCEMLLKVTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QCFNTLERSEMLLLLLRRFPETVVQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QCFNTLERSEMLLLLLRRFPETVVQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LIINNHDVRLPANLLYKYLNKAAEFYINYVTRSTQIENQHQGAQDTSDLMSPSKRSSQKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIINNHDVRLPANLLYKYLNKAAEFYINYVTRSTQIENQHQGAQDTSDLMSPSKRSSQKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 IIEGLTEKSSQIVDPWERLFKILNVVGMRCEWQMDKGRRSYGDILHRMKDLCRYMNNFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IIEGLTEKSSQIVDPWERLFKILNVVGMRCEWQMDKGRRSYGDILHRMKDLCRYMNNFDS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EAHAKYKNQVVYSTMLVFFKNAFQYVNSIQPSLFQGPNAPSQVPLVLLEDVSNVYGDVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAHAKYKNQVVYSTMLVFFKNAFQYVNSIQPSLFQGPNAPSQVPLVLLEDVSNVYGDVEI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 DRNKHIHKKRKLAEGREKTMQSSDDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRNKHIHKKRKLAEGREKTMQSSDDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARES
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 WELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLHHLAALQGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLHHLAALQGSI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 SQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 VKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 GENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIK
610 620 630 640 650 660
670 680 690
pF1KE1 --------------------------HHTVTRGITKGVKEDFRLAMERQVSRCGENLMVV
::::::::::::::::::::::::::::::::::
XP_005 PSSPPMGLLQQEFLPVLQPSIQTADRHHTVTRGITKGVKEDFRLAMERQVSRCGENLMVV
670 680 690 700 710 720
700 710
pF1KE1 LHRFCINEKILLLQTLT
:::::::::::::::::
XP_005 LHRFCINEKILLLQTLT
730
>>XP_016869095 (OMIM: 611353) PREDICTED: integrator comp (697 aa)
initn: 4418 init1: 4418 opt: 4419 Z-score: 5590.0 bits: 1044.8 E(85289): 0
Smith-Waterman score: 4419; 97.5% identity (98.4% similar) in 681 aa overlap (1-676:1-681)
10 20 30 40 50 60
pF1KE1 MSAQGDCEFLVQRARELVPQDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTATAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSAQGDCEFLVQRARELVPQDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTATAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RLLYDMFVNFPDQPVVWREISIITSALRNDSQDKQTQFLRSLFETLPGRVQCEMLLKVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLLYDMFVNFPDQPVVWREISIITSALRNDSQDKQTQFLRSLFETLPGRVQCEMLLKVTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QCFNTLERSEMLLLLLRRFPETVVQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCFNTLERSEMLLLLLRRFPETVVQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LIINNHDVRLPANLLYKYLNKAAEFYINYVTRSTQIENQHQGAQDTSDLMSPSKRSSQKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIINNHDVRLPANLLYKYLNKAAEFYINYVTRSTQIENQHQGAQDTSDLMSPSKRSSQKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 IIEGLTEKSSQIVDPWERLFKILNVVGMRCEWQMDKGRRSYGDILHRMKDLCRYMNNFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIEGLTEKSSQIVDPWERLFKILNVVGMRCEWQMDKGRRSYGDILHRMKDLCRYMNNFDS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EAHAKYKNQVVYSTMLVFFKNAFQYVNSIQPSLFQGPNAPSQVPLVLLEDVSNVYGDVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAHAKYKNQVVYSTMLVFFKNAFQYVNSIQPSLFQGPNAPSQVPLVLLEDVSNVYGDVEI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 DRNKHIHKKRKLAEGREKTMQSSDDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRNKHIHKKRKLAEGREKTMQSSDDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARES
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 WELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLHHLAALQGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLHHLAALQGSI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 SQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 VKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 GENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIK
610 620 630 640 650 660
670 680 690 700 710
pF1KE1 -----HHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLT
: . ..: :...:
XP_016 MDKDWHLPIPIYFSKIVNRNFGKNNYVVQNILNSVWG
670 680 690
>>XP_005273613 (OMIM: 611353) PREDICTED: integrator comp (736 aa)
initn: 2865 init1: 2543 opt: 4403 Z-score: 5569.3 bits: 1041.1 E(85289): 0
Smith-Waterman score: 4670; 96.3% identity (96.3% similar) in 737 aa overlap (1-711:1-736)
10 20 30 40 50 60
pF1KE1 MSAQGDCEFLVQRARELVPQDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTATAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSAQGDCEFLVQRARELVPQDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTATAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RLLYDMFVNFPDQPVVWREISIITSALRNDSQDKQTQFLRSLFETLPGRVQCEMLLKVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLLYDMFVNFPDQPVVWREISIITSALRNDSQDKQTQFLRSLFETLPGRVQCEMLLKVTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QCFNTLERSEMLLLLLRRFPETVVQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QCFNTLERSEMLLLLLRRFPETVVQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LIINNHDVRLPANLLYKYLNKAAEFYINYVTRSTQIENQHQGAQDTSDLMSPSKRSSQKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIINNHDVRLPANLLYKYLNKAAEFYINYVTRSTQIENQHQGAQDTSDLMSPSKRSSQKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 IIEGLTEKSSQIVDPWERLFKILNVVGMRCEWQMDKGRRSYGDILHRMKDLCRYMNNFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IIEGLTEKSSQIVDPWERLFKILNVVGMRCEWQMDKGRRSYGDILHRMKDLCRYMNNFDS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EAHAKYKNQVVYSTMLVFFKNAFQYVNSIQPSLFQGPNAPSQVPLVLLEDVSNVYGDVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAHAKYKNQVVYSTMLVFFKNAFQYVNSIQPSLFQGPNAPSQVPLVLLEDVSNVYGDVEI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 DRNKHIHKKRKLAEGREKTMQSSDDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARES
:::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_005 DRNKHIHKKRKLAEGREKTM-SSDDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARES
370 380 390 400 410
430 440 450 460 470 480
pF1KE1 WELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLHHLAALQGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLHHLAALQGSI
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE1 SQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSK
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE1 VKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPR
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE1 GENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIK
600 610 620 630 640 650
670 680 690
pF1KE1 --------------------------HHTVTRGITKGVKEDFRLAMERQVSRCGENLMVV
::::::::::::::::::::::::::::::::::
XP_005 PSSPPMGLLQQEFLPVLQPSIQTADRHHTVTRGITKGVKEDFRLAMERQVSRCGENLMVV
660 670 680 690 700 710
700 710
pF1KE1 LHRFCINEKILLLQTLT
:::::::::::::::::
XP_005 LHRFCINEKILLLQTLT
720 730
>>XP_016869096 (OMIM: 611353) PREDICTED: integrator comp (662 aa)
initn: 4212 init1: 4212 opt: 4212 Z-score: 5328.2 bits: 996.3 E(85289): 0
Smith-Waterman score: 4212; 99.7% identity (100.0% similar) in 630 aa overlap (1-630:1-630)
10 20 30 40 50 60
pF1KE1 MSAQGDCEFLVQRARELVPQDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTATAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSAQGDCEFLVQRARELVPQDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTATAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RLLYDMFVNFPDQPVVWREISIITSALRNDSQDKQTQFLRSLFETLPGRVQCEMLLKVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLLYDMFVNFPDQPVVWREISIITSALRNDSQDKQTQFLRSLFETLPGRVQCEMLLKVTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QCFNTLERSEMLLLLLRRFPETVVQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCFNTLERSEMLLLLLRRFPETVVQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LIINNHDVRLPANLLYKYLNKAAEFYINYVTRSTQIENQHQGAQDTSDLMSPSKRSSQKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIINNHDVRLPANLLYKYLNKAAEFYINYVTRSTQIENQHQGAQDTSDLMSPSKRSSQKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 IIEGLTEKSSQIVDPWERLFKILNVVGMRCEWQMDKGRRSYGDILHRMKDLCRYMNNFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIEGLTEKSSQIVDPWERLFKILNVVGMRCEWQMDKGRRSYGDILHRMKDLCRYMNNFDS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EAHAKYKNQVVYSTMLVFFKNAFQYVNSIQPSLFQGPNAPSQVPLVLLEDVSNVYGDVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAHAKYKNQVVYSTMLVFFKNAFQYVNSIQPSLFQGPNAPSQVPLVLLEDVSNVYGDVEI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 DRNKHIHKKRKLAEGREKTMQSSDDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRNKHIHKKRKLAEGREKTMQSSDDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARES
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 WELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLHHLAALQGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLHHLAALQGSI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 SQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 VKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 GENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIK
::::::::::::::::::::::::::::..
XP_016 GENLFLKAVNKICQQGNFQYENFFNYVTKLAPFLVGWQWASYSTAETPFPHQRKLAPFFT
610 620 630 640 650 660
>>XP_006716418 (OMIM: 611353) PREDICTED: integrator comp (624 aa)
initn: 3660 init1: 3660 opt: 3664 Z-score: 4634.6 bits: 867.9 E(85289): 0
Smith-Waterman score: 3931; 95.8% identity (95.8% similar) in 624 aa overlap (114-711:1-624)
90 100 110 120 130 140
pF1KE1 TSALRNDSQDKQTQFLRSLFETLPGRVQCEMLLKVTEQCFNTLERSEMLLLLLRRFPETV
::::::::::::::::::::::::::::::
XP_006 MLLKVTEQCFNTLERSEMLLLLLRRFPETV
10 20 30
150 160 170 180 190 200
pF1KE1 VQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLPLIINNHDVRLPANLLYKYLNKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLPLIINNHDVRLPANLLYKYLNKAA
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE1 EFYINYVTRSTQIENQHQGAQDTSDLMSPSKRSSQKYIIEGLTEKSSQIVDPWERLFKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EFYINYVTRSTQIENQHQGAQDTSDLMSPSKRSSQKYIIEGLTEKSSQIVDPWERLFKIL
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE1 NVVGMRCEWQMDKGRRSYGDILHRMKDLCRYMNNFDSEAHAKYKNQVVYSTMLVFFKNAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NVVGMRCEWQMDKGRRSYGDILHRMKDLCRYMNNFDSEAHAKYKNQVVYSTMLVFFKNAF
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE1 QYVNSIQPSLFQGPNAPSQVPLVLLEDVSNVYGDVEIDRNKHIHKKRKLAEGREKTMQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QYVNSIQPSLFQGPNAPSQVPLVLLEDVSNVYGDVEIDRNKHIHKKRKLAEGREKTMQSS
220 230 240 250 260 270
390 400 410 420 430 440
pF1KE1 DDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARESWELLYSLEFLDKEFTRICLAWKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARESWELLYSLEFLDKEFTRICLAWKT
280 290 300 310 320 330
450 460 470 480 490 500
pF1KE1 DTWLWLRIFLTDMIIYQGQYKKAIASLHHLAALQGSISQPQITGQGTLEHQRALIQLATC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DTWLWLRIFLTDMIIYQGQYKKAIASLHHLAALQGSISQPQITGQGTLEHQRALIQLATC
340 350 360 370 380 390
510 520 530 540 550 560
pF1KE1 HFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSKVKPKFRKGSDLKLLPCTSKAIMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSKVKPKFRKGSDLKLLPCTSKAIMP
400 410 420 430 440 450
570 580 590 600 610 620
pF1KE1 YCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPRGENLFLKAVNKICQQGNFQYENF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPRGENLFLKAVNKICQQGNFQYENF
460 470 480 490 500 510
630 640 650 660
pF1KE1 FNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIK-----------------------
:::::::::::::::::::::::::::::::::::::
XP_006 FNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIKPSSPPMGLLQQEFLPVLQPSIQT
520 530 540 550 560 570
670 680 690 700 710
pF1KE1 ---HHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLT
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ADRHHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLT
580 590 600 610 620
>>XP_016869097 (OMIM: 611353) PREDICTED: integrator comp (357 aa)
initn: 1885 init1: 1885 opt: 1889 Z-score: 2390.7 bits: 451.9 E(85289): 2e-126
Smith-Waterman score: 2156; 92.7% identity (92.7% similar) in 356 aa overlap (382-711:2-357)
360 370 380 390 400 410
pF1KE1 SNVYGDVEIDRNKHIHKKRKLAEGREKTMQSSDDEDCSAKGRNRHIVVNKAELANSTEVL
::::::::::::::::::::::::::::::
XP_016 MSSDDEDCSAKGRNRHIVVNKAELANSTEVL
10 20 30
420 430 440 450 460 470
pF1KE1 ESFKLARESWELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESFKLARESWELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLH
40 50 60 70 80 90
480 490 500 510 520 530
pF1KE1 HLAALQGSISQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLAALQGSISQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDG
100 110 120 130 140 150
540 550 560 570 580 590
pF1KE1 GKSQEEPSKVKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKSQEEPSKVKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVI
160 170 180 190 200 210
600 610 620 630 640 650
pF1KE1 VLLQQEWPRGENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLQQEWPRGENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLEL
220 230 240 250 260 270
660 670 680
pF1KE1 LPNQGMLIK--------------------------HHTVTRGITKGVKEDFRLAMERQVS
::::::::: :::::::::::::::::::::::::
XP_016 LPNQGMLIKPSSPPMGLLQQEFLPVLQPSIQTADRHHTVTRGITKGVKEDFRLAMERQVS
280 290 300 310 320 330
690 700 710
pF1KE1 RCGENLMVVLHRFCINEKILLLQTLT
::::::::::::::::::::::::::
XP_016 RCGENLMVVLHRFCINEKILLLQTLT
340 350
>>XP_016869098 (OMIM: 611353) PREDICTED: integrator comp (357 aa)
initn: 1885 init1: 1885 opt: 1889 Z-score: 2390.7 bits: 451.9 E(85289): 2e-126
Smith-Waterman score: 2156; 92.7% identity (92.7% similar) in 356 aa overlap (382-711:2-357)
360 370 380 390 400 410
pF1KE1 SNVYGDVEIDRNKHIHKKRKLAEGREKTMQSSDDEDCSAKGRNRHIVVNKAELANSTEVL
::::::::::::::::::::::::::::::
XP_016 MSSDDEDCSAKGRNRHIVVNKAELANSTEVL
10 20 30
420 430 440 450 460 470
pF1KE1 ESFKLARESWELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESFKLARESWELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLH
40 50 60 70 80 90
480 490 500 510 520 530
pF1KE1 HLAALQGSISQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLAALQGSISQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDG
100 110 120 130 140 150
540 550 560 570 580 590
pF1KE1 GKSQEEPSKVKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKSQEEPSKVKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVI
160 170 180 190 200 210
600 610 620 630 640 650
pF1KE1 VLLQQEWPRGENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLQQEWPRGENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLEL
220 230 240 250 260 270
660 670 680
pF1KE1 LPNQGMLIK--------------------------HHTVTRGITKGVKEDFRLAMERQVS
::::::::: :::::::::::::::::::::::::
XP_016 LPNQGMLIKPSSPPMGLLQQEFLPVLQPSIQTADRHHTVTRGITKGVKEDFRLAMERQVS
280 290 300 310 320 330
690 700 710
pF1KE1 RCGENLMVVLHRFCINEKILLLQTLT
::::::::::::::::::::::::::
XP_016 RCGENLMVVLHRFCINEKILLLQTLT
340 350
711 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 21:41:24 2016 done: Sun Nov 6 21:41:25 2016
Total Scan time: 9.570 Total Display time: 0.150
Function used was FASTA [36.3.4 Apr, 2011]