Result of FASTA (omim) for
pFN21AE1211
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1211, 132 aa
1>>>pF1KE1211 132 - 132 aa - 132 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9887+/-0.000383; mu= 12.2843+/- 0.024
mean_var=57.0484+/-11.591, 0's: 0 Z-trim(113.0): 65 B-trim: 586 in 2/47
Lambda= 0.169806
statistics sampled from 22122 (22187) to 22122 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.635), E-opt: 0.2 (0.26), width: 16
Scan time: 4.450
The best scores are: opt bits E(85289)
NP_001121798 (OMIM: 612213) binder of sperm protei ( 132) 963 243.8 6e-65
XP_016881607 (OMIM: 612213) PREDICTED: binder of s ( 132) 963 243.8 6e-65
NP_071425 (OMIM: 607443) epididymal sperm-binding ( 223) 335 90.1 1.9e-18
XP_016882619 (OMIM: 607443) PREDICTED: epididymal ( 268) 335 90.1 2.3e-18
NP_000496 (OMIM: 234000,610618,610619) coagulation ( 615) 163 48.2 2.2e-05
NP_001519 (OMIM: 604552) hepatocyte growth factor ( 655) 160 47.4 3.9e-05
NP_001284368 (OMIM: 604552) hepatocyte growth fact ( 662) 160 47.4 3.9e-05
NP_001289437 (OMIM: 120360,259600) 72 kDa type IV ( 584) 157 46.7 5.8e-05
NP_001289439 (OMIM: 120360,259600) 72 kDa type IV ( 584) 157 46.7 5.8e-05
NP_001289438 (OMIM: 120360,259600) 72 kDa type IV ( 584) 157 46.7 5.8e-05
NP_001121363 (OMIM: 120360,259600) 72 kDa type IV ( 610) 157 46.7 6.1e-05
NP_004521 (OMIM: 120360,259600) 72 kDa type IV col ( 660) 157 46.7 6.5e-05
NP_004985 (OMIM: 120361,613073) matrix metalloprot ( 707) 154 46.0 0.00011
NP_001231913 (OMIM: 602329) protein sel-1 homolog ( 301) 147 44.1 0.00018
NP_002429 (OMIM: 153618) macrophage mannose recept (1456) 153 45.9 0.00025
XP_005268046 (OMIM: 602329) PREDICTED: protein sel ( 771) 147 44.3 0.0004
NP_005056 (OMIM: 602329) protein sel-1 homolog 1 i ( 794) 147 44.3 0.00041
NP_473375 (OMIM: 135600,601894,614101) fibronectin ( 657) 140 42.5 0.0012
NP_997639 (OMIM: 135600,601894,614101) fibronectin (2176) 140 42.8 0.0032
NP_001293061 (OMIM: 135600,601894,614101) fibronec (2240) 140 42.8 0.0033
XP_005246473 (OMIM: 135600,601894,614101) PREDICTE (2246) 140 42.8 0.0033
NP_001293060 (OMIM: 135600,601894,614101) fibronec (2265) 140 42.8 0.0033
XP_005246471 (OMIM: 135600,601894,614101) PREDICTE (2266) 140 42.8 0.0033
NP_001293059 (OMIM: 135600,601894,614101) fibronec (2267) 140 42.8 0.0033
XP_005246469 (OMIM: 135600,601894,614101) PREDICTE (2271) 140 42.8 0.0033
XP_005246468 (OMIM: 135600,601894,614101) PREDICTE (2273) 140 42.8 0.0033
NP_997641 (OMIM: 135600,601894,614101) fibronectin (2296) 140 42.8 0.0033
XP_016859184 (OMIM: 135600,601894,614101) PREDICTE (2302) 140 42.8 0.0033
NP_997643 (OMIM: 135600,601894,614101) fibronectin (2330) 140 42.8 0.0034
XP_016859183 (OMIM: 135600,601894,614101) PREDICTE (2331) 140 42.8 0.0034
XP_005246467 (OMIM: 135600,601894,614101) PREDICTE (2337) 140 42.8 0.0034
NP_002017 (OMIM: 135600,601894,614101) fibronectin (2355) 140 42.8 0.0034
XP_016859182 (OMIM: 135600,601894,614101) PREDICTE (2356) 140 42.8 0.0034
XP_016859181 (OMIM: 135600,601894,614101) PREDICTE (2357) 140 42.8 0.0034
XP_005246466 (OMIM: 135600,601894,614101) PREDICTE (2361) 140 42.8 0.0034
XP_005246465 (OMIM: 135600,601894,614101) PREDICTE (2362) 140 42.8 0.0034
XP_005246464 (OMIM: 135600,601894,614101) PREDICTE (2363) 140 42.8 0.0034
XP_005246463 (OMIM: 135600,601894,614101) PREDICTE (2386) 140 42.8 0.0035
XP_005246462 (OMIM: 135600,601894,614101) PREDICTE (2387) 140 42.8 0.0035
XP_005246461 (OMIM: 135600,601894,614101) PREDICTE (2392) 140 42.8 0.0035
XP_005246460 (OMIM: 135600,601894,614101) PREDICTE (2393) 140 42.8 0.0035
XP_005246459 (OMIM: 135600,601894,614101) PREDICTE (2421) 140 42.8 0.0035
XP_005246458 (OMIM: 135600,601894,614101) PREDICTE (2427) 140 42.8 0.0035
NP_001293058 (OMIM: 135600,601894,614101) fibronec (2446) 140 42.8 0.0035
XP_005246456 (OMIM: 135600,601894,614101) PREDICTE (2452) 140 42.8 0.0035
XP_005246455 (OMIM: 135600,601894,614101) PREDICTE (2458) 140 42.8 0.0035
NP_997647 (OMIM: 135600,601894,614101) fibronectin (2477) 140 42.8 0.0036
XP_005246454 (OMIM: 135600,601894,614101) PREDICTE (2483) 140 42.8 0.0036
XP_016859090 (OMIM: 604939) PREDICTED: secretory p ( 795) 133 40.9 0.0045
NP_001007268 (OMIM: 604939) secretory phospholipas (1324) 133 41.0 0.0069
>>NP_001121798 (OMIM: 612213) binder of sperm protein ho (132 aa)
initn: 963 init1: 963 opt: 963 Z-score: 1287.0 bits: 243.8 E(85289): 6e-65
Smith-Waterman score: 963; 99.2% identity (99.2% similar) in 132 aa overlap (1-132:1-132)
10 20 30 40 50 60
pF1KE1 MGSLMLLFVETMRNSSACIFPVILNELSSTVETITHFPEVTDGECVFPFHYKNGTYYDCI
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSLMLLFVETTRNSSACIFPVILNELSSTVETITHFPEVTDGECVFPFHYKNGTYYDCI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KSKARHKWCSLNKTYEGYWKFCSAEDFANCVFPFWYRRLIYWECTDDGEAFGKKWCSLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSKARHKWCSLNKTYEGYWKFCSAEDFANCVFPFWYRRLIYWECTDDGEAFGKKWCSLTK
70 80 90 100 110 120
130
pF1KE1 NFNKDRIWKYCE
::::::::::::
NP_001 NFNKDRIWKYCE
130
>>XP_016881607 (OMIM: 612213) PREDICTED: binder of sperm (132 aa)
initn: 963 init1: 963 opt: 963 Z-score: 1287.0 bits: 243.8 E(85289): 6e-65
Smith-Waterman score: 963; 99.2% identity (99.2% similar) in 132 aa overlap (1-132:1-132)
10 20 30 40 50 60
pF1KE1 MGSLMLLFVETMRNSSACIFPVILNELSSTVETITHFPEVTDGECVFPFHYKNGTYYDCI
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSLMLLFVETTRNSSACIFPVILNELSSTVETITHFPEVTDGECVFPFHYKNGTYYDCI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KSKARHKWCSLNKTYEGYWKFCSAEDFANCVFPFWYRRLIYWECTDDGEAFGKKWCSLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSKARHKWCSLNKTYEGYWKFCSAEDFANCVFPFWYRRLIYWECTDDGEAFGKKWCSLTK
70 80 90 100 110 120
130
pF1KE1 NFNKDRIWKYCE
::::::::::::
XP_016 NFNKDRIWKYCE
130
>>NP_071425 (OMIM: 607443) epididymal sperm-binding prot (223 aa)
initn: 335 init1: 335 opt: 335 Z-score: 452.1 bits: 90.1 E(85289): 1.9e-18
Smith-Waterman score: 335; 42.7% identity (70.8% similar) in 89 aa overlap (44-132:28-116)
20 30 40 50 60 70
pF1KE1 NSSACIFPVILNELSSTVETITHFPEVTDGECVFPFHYKNGTYYDCIKSKARHKWCSLNK
:::::: ::...:. : . .. ::.
NP_071 MTRWSSYLLGWTTFLLYSYESSGGMHEECVFPFTYKGSVYFTCTHIHSLSPWCATRA
10 20 30 40 50
80 90 100 110 120 130
pF1KE1 TYEGYWKFCSAEDFANCVFPFWYRRLIYWECTDDGEAFGKKWCSLTKNFNKDRIWKYCE
.:.: ::.:..::. :.::: :: : : ..: .:. :::.:. :.. . ::.::
NP_071 VYNGQWKYCQSEDYPRCIFPFIYRGKAYNSCISQGSFLGSLWCSVTSVFDEKQQWKFCET
60 70 80 90 100 110
NP_071 NEYGGNSLRKPCIFPSIYRNNVVSDCMEDESNKLWCPTTENMDKDGKWSFCADTRISALV
120 130 140 150 160 170
>--
initn: 209 init1: 146 opt: 244 Z-score: 331.6 bits: 67.8 E(85289): 9.9e-12
Smith-Waterman score: 244; 31.6% identity (61.1% similar) in 95 aa overlap (45-131:129-223)
20 30 40 50 60 70
pF1KE1 SSACIFPVILNELSSTVETITHFPEVTDGECVFPFHYKNGTYYDCIKSKARHKWC--SLN
:.:: :.:.. ::..... . :: . :
NP_071 WCSVTSVFDEKQQWKFCETNEYGGNSLRKPCIFPSIYRNNVVSDCMEDESNKLWCPTTEN
100 110 120 130 140 150
80 90 100 110 120
pF1KE1 KTYEGYWKFCSAEDFAN------CVFPFWYRRLIYWECTDDGEAFGKKWCSLTKNFNKDR
.: :.::. .. : ::: :. :..::..: . ::. . :...:.
NP_071 MDKDGKWSFCADTRISALVPGFPCHFPFNYKNKNYFNCTNEGSKENLVWCATSYNYDQDH
160 170 180 190 200 210
130
pF1KE1 IWKYCE
: ::
NP_071 TWVYC
220
>>XP_016882619 (OMIM: 607443) PREDICTED: epididymal sper (268 aa)
initn: 335 init1: 335 opt: 335 Z-score: 450.8 bits: 90.1 E(85289): 2.3e-18
Smith-Waterman score: 335; 42.7% identity (70.8% similar) in 89 aa overlap (44-132:73-161)
20 30 40 50 60 70
pF1KE1 NSSACIFPVILNELSSTVETITHFPEVTDGECVFPFHYKNGTYYDCIKSKARHKWCSLNK
:::::: ::...:. : . .. ::.
XP_016 AAKMTRWSSYLLGWTTFLLYSYESSGGMHEECVFPFTYKGSVYFTCTHIHSLSPWCATRA
50 60 70 80 90 100
80 90 100 110 120 130
pF1KE1 TYEGYWKFCSAEDFANCVFPFWYRRLIYWECTDDGEAFGKKWCSLTKNFNKDRIWKYCE
.:.: ::.:..::. :.::: :: : : ..: .:. :::.:. :.. . ::.::
XP_016 VYNGQWKYCQSEDYPRCIFPFIYRGKAYNSCISQGSFLGSLWCSVTSVFDEKQQWKFCET
110 120 130 140 150 160
XP_016 NEYGGNSLRKPCIFPSIYRNNVVSDCMEDESNKLWCPTTENMDKDGKWSFCADTRISALV
170 180 190 200 210 220
>--
initn: 209 init1: 146 opt: 244 Z-score: 330.4 bits: 67.8 E(85289): 1.2e-11
Smith-Waterman score: 244; 31.6% identity (61.1% similar) in 95 aa overlap (45-131:174-268)
20 30 40 50 60 70
pF1KE1 SSACIFPVILNELSSTVETITHFPEVTDGECVFPFHYKNGTYYDCIKSKARHKWC--SLN
:.:: :.:.. ::..... . :: . :
XP_016 WCSVTSVFDEKQQWKFCETNEYGGNSLRKPCIFPSIYRNNVVSDCMEDESNKLWCPTTEN
150 160 170 180 190 200
80 90 100 110 120
pF1KE1 KTYEGYWKFCSAEDFAN------CVFPFWYRRLIYWECTDDGEAFGKKWCSLTKNFNKDR
.: :.::. .. : ::: :. :..::..: . ::. . :...:.
XP_016 MDKDGKWSFCADTRISALVPGFPCHFPFNYKNKNYFNCTNEGSKENLVWCATSYNYDQDH
210 220 230 240 250 260
130
pF1KE1 IWKYCE
: ::
XP_016 TWVYC
>>NP_000496 (OMIM: 234000,610618,610619) coagulation fac (615 aa)
initn: 163 init1: 163 opt: 163 Z-score: 217.6 bits: 48.2 E(85289): 2.2e-05
Smith-Waterman score: 163; 45.2% identity (66.7% similar) in 42 aa overlap (90-131:47-88)
60 70 80 90 100 110
pF1KE1 IKSKARHKWCSLNKTYEGYWKFCSAEDFANCVFPFWYRRLIYWECTDDGEAFGKKWCSLT
: ::: :.: .: .:: :. . ::. :
NP_000 TLSIPPWEAPKEHKYKAEEHTVVLTVTGEPCHFPFQYHRQLYHKCTHKGRPGPQPWCATT
20 30 40 50 60 70
120 130
pF1KE1 KNFNKDRIWKYCE
::..:. : ::
NP_000 PNFDQDQRWGYCLEPKKVKDHCSKHSPCQKGGTCVNMPSGPHCLCPQHLTGNHCQKEKCF
80 90 100 110 120 130
>>NP_001519 (OMIM: 604552) hepatocyte growth factor acti (655 aa)
initn: 106 init1: 106 opt: 160 Z-score: 213.2 bits: 47.4 E(85289): 3.9e-05
Smith-Waterman score: 160; 44.7% identity (63.8% similar) in 47 aa overlap (85-131:103-148)
60 70 80 90 100 110
pF1KE1 TYYDCIKSKARHKWCSLNKTYEGYWKFCSAEDFANCVFPFWYRRLIYWECTDDGEAFGKK
:: : ::: : . ::..: : .:
NP_001 PEAEGPQSGGLPPPPRAVPSSSSPQAQALTEDGRPCRFPFRYGGRMLHACTSEGSAH-RK
80 90 100 110 120 130
120 130
pF1KE1 WCSLTKNFNKDRIWKYCE
::. :.:...:: : ::
NP_001 WCATTHNYDRDRAWGYCVEATPPPGGPAALDPCASGPCLNGGSCSNTQDPQSYHCSCPRA
140 150 160 170 180 190
>>NP_001284368 (OMIM: 604552) hepatocyte growth factor a (662 aa)
initn: 106 init1: 106 opt: 160 Z-score: 213.2 bits: 47.4 E(85289): 3.9e-05
Smith-Waterman score: 160; 44.7% identity (63.8% similar) in 47 aa overlap (85-131:103-148)
60 70 80 90 100 110
pF1KE1 TYYDCIKSKARHKWCSLNKTYEGYWKFCSAEDFANCVFPFWYRRLIYWECTDDGEAFGKK
:: : ::: : . ::..: : .:
NP_001 PEAEGPQSGGLPPPPRAVPSSSSPQAQALTEDGRPCRFPFRYGGRMLHACTSEGSAH-RK
80 90 100 110 120 130
120 130
pF1KE1 WCSLTKNFNKDRIWKYCE
::. :.:...:: : ::
NP_001 WCATTHNYDRDRAWGYCVEATPPPGGPAALDPCASGPCLNGGSCSNTQDPQSYHCSCPRA
140 150 160 170 180 190
>>NP_001289437 (OMIM: 120360,259600) 72 kDa type IV coll (584 aa)
initn: 373 init1: 154 opt: 157 Z-score: 210.0 bits: 46.7 E(85289): 5.8e-05
Smith-Waterman score: 218; 34.7% identity (56.4% similar) in 101 aa overlap (45-131:215-314)
20 30 40 50 60 70
pF1KE1 SSACIFPVILNELSSTVETITHFPEVTDGECVFPFHYKNGTYYDCIKSKAR---HKWCSL
: :::... :: :: ...: ..::.
NP_001 TTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQ-GTSYDSCTTEGRTDGYRWCGT
190 200 210 220 230 240
80 90 100 110 120
pF1KE1 NKTYEGYWK--FC---------SAEDFANCVFPFWYRRLIYWECTDDGEAFGKKWCSLTK
.. :. : :: . . : ::::: . : ::. :.. :: ::. :
NP_001 TEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTA
250 260 270 280 290 300
130
pF1KE1 NFNKDRIWKYCE
:.. :: : .:
NP_001 NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIK
310 320 330 340 350 360
>>NP_001289439 (OMIM: 120360,259600) 72 kDa type IV coll (584 aa)
initn: 373 init1: 154 opt: 157 Z-score: 210.0 bits: 46.7 E(85289): 5.8e-05
Smith-Waterman score: 218; 34.7% identity (56.4% similar) in 101 aa overlap (45-131:215-314)
20 30 40 50 60 70
pF1KE1 SSACIFPVILNELSSTVETITHFPEVTDGECVFPFHYKNGTYYDCIKSKAR---HKWCSL
: :::... :: :: ...: ..::.
NP_001 TTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQ-GTSYDSCTTEGRTDGYRWCGT
190 200 210 220 230 240
80 90 100 110 120
pF1KE1 NKTYEGYWK--FC---------SAEDFANCVFPFWYRRLIYWECTDDGEAFGKKWCSLTK
.. :. : :: . . : ::::: . : ::. :.. :: ::. :
NP_001 TEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTA
250 260 270 280 290 300
130
pF1KE1 NFNKDRIWKYCE
:.. :: : .:
NP_001 NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIK
310 320 330 340 350 360
>>NP_001289438 (OMIM: 120360,259600) 72 kDa type IV coll (584 aa)
initn: 373 init1: 154 opt: 157 Z-score: 210.0 bits: 46.7 E(85289): 5.8e-05
Smith-Waterman score: 218; 34.7% identity (56.4% similar) in 101 aa overlap (45-131:215-314)
20 30 40 50 60 70
pF1KE1 SSACIFPVILNELSSTVETITHFPEVTDGECVFPFHYKNGTYYDCIKSKAR---HKWCSL
: :::... :: :: ...: ..::.
NP_001 TTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQ-GTSYDSCTTEGRTDGYRWCGT
190 200 210 220 230 240
80 90 100 110 120
pF1KE1 NKTYEGYWK--FC---------SAEDFANCVFPFWYRRLIYWECTDDGEAFGKKWCSLTK
.. :. : :: . . : ::::: . : ::. :.. :: ::. :
NP_001 TEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTA
250 260 270 280 290 300
130
pF1KE1 NFNKDRIWKYCE
:.. :: : .:
NP_001 NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIK
310 320 330 340 350 360
132 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 10:34:49 2016 done: Sun Nov 6 10:34:50 2016
Total Scan time: 4.450 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]