Result of FASTA (omim) for
pFN21AE1183
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1183, 703 aa
1>>>pF1KE1183 703 - 703 aa - 703 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3184+/-0.000319; mu= 11.3787+/- 0.020
mean_var=122.6043+/-24.199, 0's: 0 Z-trim(119.8): 93 B-trim: 65 in 1/56
Lambda= 0.115830
statistics sampled from 34227 (34332) to 34227 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.403), width: 16
Scan time: 13.040
The best scores are: opt bits E(85289)
XP_011535609 (OMIM: 603526) PREDICTED: metastasis- ( 759) 4681 793.4 0
XP_016877243 (OMIM: 603526) PREDICTED: metastasis- ( 783) 4353 738.6 2.2e-212
XP_011535612 (OMIM: 603526) PREDICTED: metastasis- ( 742) 4210 714.7 3.2e-205
NP_004680 (OMIM: 603526) metastasis-associated pro ( 715) 4034 685.3 2.2e-196
XP_016877246 (OMIM: 603526) PREDICTED: metastasis- ( 743) 4020 682.9 1.2e-195
XP_011535608 (OMIM: 603526) PREDICTED: metastasis- ( 771) 3975 675.4 2.2e-193
XP_016877242 (OMIM: 603526) PREDICTED: metastasis- ( 795) 3975 675.4 2.3e-193
XP_011535607 (OMIM: 603526) PREDICTED: metastasis- ( 775) 3961 673.1 1.1e-192
XP_016877241 (OMIM: 603526) PREDICTED: metastasis- ( 799) 3961 673.1 1.2e-192
XP_016877245 (OMIM: 603526) PREDICTED: metastasis- ( 772) 3814 648.5 2.8e-185
XP_011535611 (OMIM: 603526) PREDICTED: metastasis- ( 754) 3504 596.7 1.1e-169
XP_016877247 (OMIM: 603526) PREDICTED: metastasis- ( 726) 3490 594.4 5.3e-169
XP_011535610 (OMIM: 603526) PREDICTED: metastasis- ( 758) 3490 594.4 5.4e-169
XP_016877244 (OMIM: 603526) PREDICTED: metastasis- ( 782) 3490 594.4 5.6e-169
XP_016877248 (OMIM: 603526) PREDICTED: metastasis- ( 657) 3461 589.5 1.4e-167
NP_001190187 (OMIM: 603526) metastasis-associated ( 430) 2625 449.7 1.1e-125
NP_004730 (OMIM: 603947) metastasis-associated pro ( 668) 2163 372.6 2.8e-102
NP_065795 (OMIM: 609050) metastasis-associated pro ( 515) 1968 339.9 1.4e-92
XP_005264516 (OMIM: 609050) PREDICTED: metastasis- ( 538) 1968 340.0 1.5e-92
NP_001317371 (OMIM: 609050) metastasis-associated ( 594) 1968 340.0 1.6e-92
NP_001269685 (OMIM: 609050) metastasis-associated ( 537) 1955 337.8 6.7e-92
NP_001269684 (OMIM: 609050) metastasis-associated ( 537) 1955 337.8 6.7e-92
NP_001317372 (OMIM: 609050) metastasis-associated ( 593) 1955 337.8 7.3e-92
NP_001317221 (OMIM: 603947) metastasis-associated ( 495) 1665 289.3 2.4e-77
XP_016860051 (OMIM: 609050) PREDICTED: metastasis- ( 341) 1510 263.3 1.1e-69
NP_001317373 (OMIM: 609050) metastasis-associated ( 530) 867 156.0 3.6e-37
XP_011539813 (OMIM: 605226,616975) PREDICTED: argi (1181) 416 80.8 3.4e-14
XP_011539812 (OMIM: 605226,616975) PREDICTED: argi (1524) 416 80.8 4.3e-14
NP_001036146 (OMIM: 605226,616975) arginine-glutam (1566) 416 80.8 4.4e-14
XP_016856847 (OMIM: 605226,616975) PREDICTED: argi (1566) 416 80.8 4.4e-14
NP_036234 (OMIM: 605226,616975) arginine-glutamic (1566) 416 80.8 4.4e-14
XP_016856848 (OMIM: 605226,616975) PREDICTED: argi (1566) 416 80.8 4.4e-14
XP_005263521 (OMIM: 605226,616975) PREDICTED: argi (1566) 416 80.8 4.4e-14
XP_005263523 (OMIM: 605226,616975) PREDICTED: argi (1298) 330 66.4 7.9e-10
NP_055971 (OMIM: 607675) REST corepressor 1 [Homo ( 485) 187 42.3 0.0053
>>XP_011535609 (OMIM: 603526) PREDICTED: metastasis-asso (759 aa)
initn: 4681 init1: 4681 opt: 4681 Z-score: 4230.5 bits: 793.4 E(85289): 0
Smith-Waterman score: 4681; 99.9% identity (100.0% similar) in 694 aa overlap (10-703:66-759)
10 20 30
pF1KE1 MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVE
::::::::::::::::::::::::::::::
XP_011 CVCSPWSLWPGVLGAVRPPTCPPRGLPLPADYVYFENSSSNPYLIRRIEELNKTANGNVE
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE1 AKVVCFYRRRDISSTLIALADKHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKVVCFYRRRDISSTLIALADKHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKL
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE1 KHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKT
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE1 LLADKGEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLADKGEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARS
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE1 VGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPV
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE1 LCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQ
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE1 KRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTT
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE1 QSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSG
460 470 480 490 500 510
460 470 480 490 500 510
pF1KE1 SPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEA
520 530 540 550 560 570
520 530 540 550 560 570
pF1KE1 SQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTI
580 590 600 610 620 630
580 590 600 610 620 630
pF1KE1 LGKRSYEQHNGVDGLANHGQTRHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWI
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_011 LGKRSYEQHNGVDGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWI
640 650 660 670 680 690
640 650 660 670 680 690
pF1KE1 DAPDDVFYMATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAPDDVFYMATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPI
700 710 720 730 740 750
700
pF1KE1 VIED
::::
XP_011 VIED
>>XP_016877243 (OMIM: 603526) PREDICTED: metastasis-asso (783 aa)
initn: 4352 init1: 4352 opt: 4353 Z-score: 3934.1 bits: 738.6 E(85289): 2.2e-212
Smith-Waterman score: 4623; 96.5% identity (96.7% similar) in 718 aa overlap (10-703:66-783)
10 20 30
pF1KE1 MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVE
::::::::::::::::::::::::::::::
XP_016 CVCSPWSLWPGVLGAVRPPTCPPRGLPLPADYVYFENSSSNPYLIRRIEELNKTANGNVE
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE1 AKVVCFYRRRDISSTLIALADKHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKVVCFYRRRDISSTLIALADKHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKL
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE1 KHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKT
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE1 LLADKGEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLADKGEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARS
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE1 VGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPV
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE1 LCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQ
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE1 KRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTT
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE1 QSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSG
460 470 480 490 500 510
460 470 480 490 500 510
pF1KE1 SPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEA
520 530 540 550 560 570
520 530 540 550 560 570
pF1KE1 SQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTI
580 590 600 610 620 630
580 590 600 610 620 630
pF1KE1 LGKRSYEQHNGVDGLANHGQTRHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWI
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_016 LGKRSYEQHNGVDGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWI
640 650 660 670 680 690
640 650 660 670
pF1KE1 DAPDDVFYMATEETR------------------------KIRKLLSSSETKRAARRPYKP
::::::::::::::: :::::::::::::::::::::
XP_016 DAPDDVFYMATEETRWGLPRAGGRAPHSVPALTTTSAHRKIRKLLSSSETKRAARRPYKP
700 710 720 730 740 750
680 690 700
pF1KE1 IALRQSQALPPRPPPPAPVNDEPIVIED
::::::::::::::::::::::::::::
XP_016 IALRQSQALPPRPPPPAPVNDEPIVIED
760 770 780
>>XP_011535612 (OMIM: 603526) PREDICTED: metastasis-asso (742 aa)
initn: 4541 init1: 4210 opt: 4210 Z-score: 3805.3 bits: 714.7 E(85289): 3.2e-205
Smith-Waterman score: 4510; 97.3% identity (97.4% similar) in 694 aa overlap (10-703:66-742)
10 20 30
pF1KE1 MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVE
::::::::::::::::::::::::::::::
XP_011 CVCSPWSLWPGVLGAVRPPTCPPRGLPLPADYVYFENSSSNPYLIRRIEELNKTANGNVE
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE1 AKVVCFYRRRDISSTLIALADKHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKL
:::::::::::::::::::::::: ::::::::::::::::::
XP_011 AKVVCFYRRRDISSTLIALADKHAR-----------------EIEEEMENPEMVDLPEKL
100 110 120 130
100 110 120 130 140 150
pF1KE1 KHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKT
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE1 LLADKGEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLADKGEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARS
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE1 VGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPV
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE1 LCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQ
320 330 340 350 360 370
340 350 360 370 380 390
pF1KE1 KRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTT
380 390 400 410 420 430
400 410 420 430 440 450
pF1KE1 QSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSG
440 450 460 470 480 490
460 470 480 490 500 510
pF1KE1 SPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEA
500 510 520 530 540 550
520 530 540 550 560 570
pF1KE1 SQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTI
560 570 580 590 600 610
580 590 600 610 620 630
pF1KE1 LGKRSYEQHNGVDGLANHGQTRHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWI
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_011 LGKRSYEQHNGVDGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWI
620 630 640 650 660 670
640 650 660 670 680 690
pF1KE1 DAPDDVFYMATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAPDDVFYMATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPI
680 690 700 710 720 730
700
pF1KE1 VIED
::::
XP_011 VIED
740
>>NP_004680 (OMIM: 603526) metastasis-associated protein (715 aa)
initn: 3996 init1: 3996 opt: 4034 Z-score: 3646.6 bits: 685.3 E(85289): 2.2e-196
Smith-Waterman score: 4706; 98.2% identity (98.3% similar) in 715 aa overlap (1-703:1-715)
10 20 30 40 50 60
pF1KE1 MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIALAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIALAD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQLRHRELFLSRQLESLPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQLRHRELFLSRQLESLPAT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 HIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 KPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 WTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSGSPKFAMKTRQAFYLHTTKLTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 WTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSGSPKFAMKTRQAFYLHTTKLTR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 IARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSPLVLKQAVRKPLEAVLRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSPLVLKQAVRKPLEAVLRY
490 500 510 520 530 540
550 560 570 580 590
pF1KE1 LETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQHNGVDG-------
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQHNGVDGNMKKRLL
550 560 570 580 590 600
600 610 620 630 640
pF1KE1 -----LANHGQTRHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYM
::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MPSRGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYM
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE1 ATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPIVIED
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPIVIED
670 680 690 700 710
>>XP_016877246 (OMIM: 603526) PREDICTED: metastasis-asso (743 aa)
initn: 4319 init1: 3996 opt: 4020 Z-score: 3633.7 bits: 682.9 E(85289): 1.2e-195
Smith-Waterman score: 4587; 94.4% identity (94.6% similar) in 735 aa overlap (1-695:1-735)
10 20 30 40 50 60
pF1KE1 MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIALAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIALAD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQLRHRELFLSRQLESLPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQLRHRELFLSRQLESLPAT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 HIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 KPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 WTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSGSPKFAMKTRQAFYLHTTKLTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSGSPKFAMKTRQAFYLHTTKLTR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 IARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSPLVLKQAVRKPLEAVLRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSPLVLKQAVRKPLEAVLRY
490 500 510 520 530 540
550 560 570 580 590
pF1KE1 LETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQHNGVDG-------
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQHNGVDGNMKKRLL
550 560 570 580 590 600
600 610 620 630 640
pF1KE1 ---------LANHGQTRHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDD
::::::.::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPSRGTYLGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDD
610 620 630 640 650 660
650 660 670 680
pF1KE1 VFYMATEETR------------------------KIRKLLSSSETKRAARRPYKPIALRQ
:::::::::: ::::::::::::::::::::::::::
XP_016 VFYMATEETRWGLPRAGGRAPHSVPALTTTSAHRKIRKLLSSSETKRAARRPYKPIALRQ
670 680 690 700 710 720
690 700
pF1KE1 SQALPPRPPPPAPVNDEPIVIED
:::::::::::::::
XP_016 SQALPPRPPPPAPVNDEPIVIED
730 740
>>XP_011535608 (OMIM: 603526) PREDICTED: metastasis-asso (771 aa)
initn: 3937 init1: 3937 opt: 3975 Z-score: 3592.8 bits: 675.4 E(85289): 2.2e-193
Smith-Waterman score: 4647; 98.2% identity (98.3% similar) in 706 aa overlap (10-703:66-771)
10 20 30
pF1KE1 MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVE
::::::::::::::::::::::::::::::
XP_011 CVCSPWSLWPGVLGAVRPPTCPPRGLPLPADYVYFENSSSNPYLIRRIEELNKTANGNVE
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE1 AKVVCFYRRRDISSTLIALADKHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKVVCFYRRRDISSTLIALADKHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKL
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE1 KHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKT
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE1 LLADKGEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLADKGEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARS
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE1 VGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPV
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE1 LCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQ
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE1 KRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTT
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE1 QSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSG
460 470 480 490 500 510
460 470 480 490 500 510
pF1KE1 SPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEA
520 530 540 550 560 570
520 530 540 550 560 570
pF1KE1 SQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTI
580 590 600 610 620 630
580 590 600 610 620
pF1KE1 LGKRSYEQHNGVDG------------LANHGQTRHMGPSRNLLLNGKSYPTKVRLIRGGS
:::::::::::::: ::::::.:::::::::::::::::::::::::::
XP_011 LGKRSYEQHNGVDGNMKKRLLMPSRGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGS
640 650 660 670 680 690
630 640 650 660 670 680
pF1KE1 LPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPR
700 710 720 730 740 750
690 700
pF1KE1 PPPPAPVNDEPIVIED
::::::::::::::::
XP_011 PPPPAPVNDEPIVIED
760 770
>>XP_016877242 (OMIM: 603526) PREDICTED: metastasis-asso (795 aa)
initn: 4260 init1: 3937 opt: 3975 Z-score: 3592.6 bits: 675.4 E(85289): 2.3e-193
Smith-Waterman score: 4565; 94.9% identity (95.0% similar) in 726 aa overlap (10-699:66-791)
10 20 30
pF1KE1 MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVE
::::::::::::::::::::::::::::::
XP_016 CVCSPWSLWPGVLGAVRPPTCPPRGLPLPADYVYFENSSSNPYLIRRIEELNKTANGNVE
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE1 AKVVCFYRRRDISSTLIALADKHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKVVCFYRRRDISSTLIALADKHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKL
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE1 KHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKT
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE1 LLADKGEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLADKGEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARS
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE1 VGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPV
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE1 LCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQ
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE1 KRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTT
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE1 QSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSG
460 470 480 490 500 510
460 470 480 490 500 510
pF1KE1 SPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEA
520 530 540 550 560 570
520 530 540 550 560 570
pF1KE1 SQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTI
580 590 600 610 620 630
580 590 600 610 620
pF1KE1 LGKRSYEQHNGVDG------------LANHGQTRHMGPSRNLLLNGKSYPTKVRLIRGGS
:::::::::::::: ::::::.:::::::::::::::::::::::::::
XP_016 LGKRSYEQHNGVDGNMKKRLLMPSRGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGS
640 650 660 670 680 690
630 640 650 660
pF1KE1 LPPVKRRRMNWIDAPDDVFYMATEETR------------------------KIRKLLSSS
::::::::::::::::::::::::::: :::::::::
XP_016 LPPVKRRRMNWIDAPDDVFYMATEETRWGLPRAGGRAPHSVPALTTTSAHRKIRKLLSSS
700 710 720 730 740 750
670 680 690 700
pF1KE1 ETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPIVIED
::::::::::::::::::::::::::::::::::::
XP_016 ETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPIVIED
760 770 780 790
>>XP_011535607 (OMIM: 603526) PREDICTED: metastasis-asso (775 aa)
initn: 3937 init1: 3937 opt: 3961 Z-score: 3580.1 bits: 673.1 E(85289): 1.1e-192
Smith-Waterman score: 4639; 97.6% identity (97.7% similar) in 710 aa overlap (10-703:66-775)
10 20 30
pF1KE1 MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVE
::::::::::::::::::::::::::::::
XP_011 CVCSPWSLWPGVLGAVRPPTCPPRGLPLPADYVYFENSSSNPYLIRRIEELNKTANGNVE
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE1 AKVVCFYRRRDISSTLIALADKHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKVVCFYRRRDISSTLIALADKHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKL
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE1 KHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKT
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE1 LLADKGEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLADKGEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARS
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE1 VGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPV
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE1 LCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQ
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE1 KRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTT
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE1 QSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSG
460 470 480 490 500 510
460 470 480 490 500 510
pF1KE1 SPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEA
520 530 540 550 560 570
520 530 540 550 560 570
pF1KE1 SQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTI
580 590 600 610 620 630
580 590 600 610 620
pF1KE1 LGKRSYEQHNGVDG----------------LANHGQTRHMGPSRNLLLNGKSYPTKVRLI
:::::::::::::: ::::::.:::::::::::::::::::::::
XP_011 LGKRSYEQHNGVDGNMKKRLLMPSRGTYLGLANHGQARHMGPSRNLLLNGKSYPTKVRLI
640 650 660 670 680 690
630 640 650 660 670 680
pF1KE1 RGGSLPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSETKRAARRPYKPIALRQSQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGGSLPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSETKRAARRPYKPIALRQSQA
700 710 720 730 740 750
690 700
pF1KE1 LPPRPPPPAPVNDEPIVIED
::::::::::::::::::::
XP_011 LPPRPPPPAPVNDEPIVIED
760 770
>>XP_016877241 (OMIM: 603526) PREDICTED: metastasis-asso (799 aa)
initn: 4260 init1: 3937 opt: 3961 Z-score: 3579.9 bits: 673.1 E(85289): 1.2e-192
Smith-Waterman score: 4528; 94.4% identity (94.5% similar) in 726 aa overlap (10-695:66-791)
10 20 30
pF1KE1 MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVE
::::::::::::::::::::::::::::::
XP_016 CVCSPWSLWPGVLGAVRPPTCPPRGLPLPADYVYFENSSSNPYLIRRIEELNKTANGNVE
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE1 AKVVCFYRRRDISSTLIALADKHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKVVCFYRRRDISSTLIALADKHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKL
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE1 KHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKT
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE1 LLADKGEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLADKGEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARS
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE1 VGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPV
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE1 LCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQ
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE1 KRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTT
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE1 QSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSG
460 470 480 490 500 510
460 470 480 490 500 510
pF1KE1 SPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEA
520 530 540 550 560 570
520 530 540 550 560 570
pF1KE1 SQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTI
580 590 600 610 620 630
580 590 600 610 620
pF1KE1 LGKRSYEQHNGVDG----------------LANHGQTRHMGPSRNLLLNGKSYPTKVRLI
:::::::::::::: ::::::.:::::::::::::::::::::::
XP_016 LGKRSYEQHNGVDGNMKKRLLMPSRGTYLGLANHGQARHMGPSRNLLLNGKSYPTKVRLI
640 650 660 670 680 690
630 640 650
pF1KE1 RGGSLPPVKRRRMNWIDAPDDVFYMATEETR------------------------KIRKL
::::::::::::::::::::::::::::::: :::::
XP_016 RGGSLPPVKRRRMNWIDAPDDVFYMATEETRWGLPRAGGRAPHSVPALTTTSAHRKIRKL
700 710 720 730 740 750
660 670 680 690 700
pF1KE1 LSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPIVIED
::::::::::::::::::::::::::::::::::::
XP_016 LSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPIVIED
760 770 780 790
>>XP_016877245 (OMIM: 603526) PREDICTED: metastasis-asso (772 aa)
initn: 4113 init1: 3790 opt: 3814 Z-score: 3447.4 bits: 648.5 E(85289): 2.8e-185
Smith-Waterman score: 4381; 94.0% identity (94.3% similar) in 704 aa overlap (32-695:61-764)
10 20 30 40 50 60
pF1KE1 AANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIALADK
.:::::::::::::::::::::::::::::
XP_016 PDAHHVEKNPQACDRVRPVPSTPRSSRRGFQTANGNVEAKVVCFYRRRDISSTLIALADK
40 50 60 70 80 90
70 80 90 100 110 120
pF1KE1 HATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQLRHRELFLSRQLESLPATH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQLRHRELFLSRQLESLPATH
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE1 IRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDLL
160 170 180 190 200 210
190 200 210 220 230 240
pF1KE1 KEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHMS
220 230 240 250 260 270
250 260 270 280 290 300
pF1KE1 AAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALE
280 290 300 310 320 330
310 320 330 340 350 360
pF1KE1 KYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYNK
340 350 360 370 380 390
370 380 390 400 410 420
pF1KE1 PNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASCW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASCW
400 410 420 430 440 450
430 440 450 460 470 480
pF1KE1 TYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSGSPKFAMKTRQAFYLHTTKLTRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSGSPKFAMKTRQAFYLHTTKLTRI
460 470 480 490 500 510
490 500 510 520 530 540
pF1KE1 ARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSPLVLKQAVRKPLEAVLRYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSPLVLKQAVRKPLEAVLRYL
520 530 540 550 560 570
550 560 570 580 590
pF1KE1 ETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQHNGVDG--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQHNGVDGNMKKRLLM
580 590 600 610 620 630
600 610 620 630 640
pF1KE1 --------LANHGQTRHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDV
::::::.:::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSRGTYLGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDV
640 650 660 670 680 690
650 660 670 680
pF1KE1 FYMATEETR------------------------KIRKLLSSSETKRAARRPYKPIALRQS
::::::::: :::::::::::::::::::::::::::
XP_016 FYMATEETRWGLPRAGGRAPHSVPALTTTSAHRKIRKLLSSSETKRAARRPYKPIALRQS
700 710 720 730 740 750
690 700
pF1KE1 QALPPRPPPPAPVNDEPIVIED
::::::::::::::
XP_016 QALPPRPPPPAPVNDEPIVIED
760 770
703 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:02:41 2016 done: Sun Nov 6 22:02:43 2016
Total Scan time: 13.040 Total Display time: 0.240
Function used was FASTA [36.3.4 Apr, 2011]