Result of FASTA (omim) for
pFN21AE1177
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1177, 684 aa
1>>>pF1KE1177 684 - 684 aa - 684 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1470+/-0.000368; mu= 16.5620+/- 0.023
mean_var=102.0621+/-20.381, 0's: 0 Z-trim(115.6): 196 B-trim: 50 in 1/54
Lambda= 0.126953
statistics sampled from 25961 (26192) to 25961 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.307), width: 16
Scan time: 10.970
The best scores are: opt bits E(85289)
NP_006506 (OMIM: 609834) histone-lysine N-methyltr ( 684) 4769 884.5 0
XP_016862521 (OMIM: 609834) PREDICTED: histone-lys ( 479) 3285 612.5 1.1e-174
NP_001230652 (OMIM: 609834) histone-lysine N-methy ( 545) 2640 494.4 4.6e-139
NP_001307605 (OMIM: 609834) histone-lysine N-methy ( 406) 2625 491.6 2.4e-138
XP_006713355 (OMIM: 609834) PREDICTED: histone-lys ( 448) 2625 491.6 2.6e-138
NP_001307606 (OMIM: 609834) histone-lysine N-methy ( 428) 2591 485.4 1.9e-136
XP_006713357 (OMIM: 609834) PREDICTED: histone-lys ( 428) 2591 485.4 1.9e-136
NP_001263254 (OMIM: 609834) histone-lysine N-methy ( 365) 2423 454.6 3.1e-127
NP_001307607 (OMIM: 609834) histone-lysine N-methy ( 396) 2397 449.8 8.9e-126
XP_011544282 (OMIM: 605847) PREDICTED: B-cell CLL/ ( 293) 527 107.2 8.9e-23
XP_011517964 (OMIM: 606503) PREDICTED: histone-lys ( 350) 483 99.2 2.7e-20
NP_001180354 (OMIM: 606503) histone-lysine N-methy ( 350) 483 99.2 2.7e-20
XP_006717566 (OMIM: 606503) PREDICTED: histone-lys ( 350) 483 99.2 2.7e-20
XP_016872126 (OMIM: 606503) PREDICTED: histone-lys ( 350) 483 99.2 2.7e-20
NP_078946 (OMIM: 606503) histone-lysine N-methyltr ( 350) 483 99.2 2.7e-20
NP_001180353 (OMIM: 606503) histone-lysine N-methy ( 410) 483 99.3 3.1e-20
NP_003164 (OMIM: 300254) histone-lysine N-methyltr ( 412) 467 96.4 2.4e-19
NP_001269095 (OMIM: 300254) histone-lysine N-methy ( 423) 467 96.4 2.4e-19
NP_001305762 (OMIM: 604599) histone-lysine N-methy (1008) 399 84.2 2.7e-15
NP_079532 (OMIM: 604599) histone-lysine N-methyltr (1176) 399 84.2 3e-15
XP_016865691 (OMIM: 604599) PREDICTED: histone-lys (1183) 399 84.2 3e-15
NP_006700 (OMIM: 604599) histone-lysine N-methyltr (1210) 399 84.2 3.1e-15
XP_006715039 (OMIM: 604599) PREDICTED: histone-lys (1217) 399 84.2 3.1e-15
NP_001276342 (OMIM: 604599) histone-lysine N-methy (1233) 399 84.3 3.1e-15
XP_006715038 (OMIM: 604599) PREDICTED: histone-lys (1240) 399 84.3 3.1e-15
XP_005248881 (OMIM: 604599) PREDICTED: histone-lys (1267) 399 84.3 3.2e-15
XP_006715037 (OMIM: 604599) PREDICTED: histone-lys (1274) 399 84.3 3.2e-15
XP_011517333 (OMIM: 607001,610253) PREDICTED: hist ( 488) 392 82.7 3.7e-15
XP_011517332 (OMIM: 607001,610253) PREDICTED: hist ( 559) 392 82.7 4.1e-15
XP_011517331 (OMIM: 607001,610253) PREDICTED: hist ( 775) 392 82.8 5.3e-15
XP_011517335 (OMIM: 607001,610253) PREDICTED: hist (1246) 392 83.0 7.6e-15
XP_011517328 (OMIM: 607001,610253) PREDICTED: hist (1253) 392 83.0 7.7e-15
XP_016870626 (OMIM: 607001,610253) PREDICTED: hist (1260) 392 83.0 7.7e-15
XP_016870627 (OMIM: 607001,610253) PREDICTED: hist (1260) 392 83.0 7.7e-15
XP_016870625 (OMIM: 607001,610253) PREDICTED: hist (1265) 392 83.0 7.7e-15
XP_005266167 (OMIM: 607001,610253) PREDICTED: hist (1267) 392 83.0 7.7e-15
XP_011517327 (OMIM: 607001,610253) PREDICTED: hist (1267) 392 83.0 7.7e-15
XP_011517326 (OMIM: 607001,610253) PREDICTED: hist (1275) 392 83.0 7.8e-15
XP_016870624 (OMIM: 607001,610253) PREDICTED: hist (1291) 392 83.0 7.9e-15
XP_006717351 (OMIM: 607001,610253) PREDICTED: hist (1292) 392 83.0 7.9e-15
XP_016870623 (OMIM: 607001,610253) PREDICTED: hist (1293) 392 83.0 7.9e-15
XP_011517325 (OMIM: 607001,610253) PREDICTED: hist (1294) 392 83.0 7.9e-15
XP_005266162 (OMIM: 607001,610253) PREDICTED: hist (1295) 392 83.0 7.9e-15
NP_079033 (OMIM: 607001,610253) histone-lysine N-m (1298) 392 83.0 7.9e-15
XP_011517324 (OMIM: 607001,610253) PREDICTED: hist (1300) 392 83.0 7.9e-15
XP_011517323 (OMIM: 607001,610253) PREDICTED: hist (1301) 392 83.0 7.9e-15
XP_011508072 (OMIM: 607999) PREDICTED: histone-lys (1244) 310 68.0 2.5e-10
XP_016857277 (OMIM: 607999) PREDICTED: histone-lys (1244) 310 68.0 2.5e-10
XP_016857275 (OMIM: 607999) PREDICTED: histone-lys (2663) 310 68.2 4.6e-10
XP_006711515 (OMIM: 607999) PREDICTED: histone-lys (2904) 310 68.2 4.9e-10
>>NP_006506 (OMIM: 609834) histone-lysine N-methyltransf (684 aa)
initn: 4769 init1: 4769 opt: 4769 Z-score: 4723.7 bits: 884.5 E(85289): 0
Smith-Waterman score: 4769; 100.0% identity (100.0% similar) in 684 aa overlap (1-684:1-684)
10 20 30 40 50 60
pF1KE1 MFAEAAKTTRPCGMAEFKEKPEAPTEQLDVACGQENLPVGAWPPGAAPAPFQYTPDHVVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MFAEAAKTTRPCGMAEFKEKPEAPTEQLDVACGQENLPVGAWPPGAAPAPFQYTPDHVVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PGADIDPTQITFPGCICVKTPCLPGTCSCLRHGENYDDNSCLRDIGSGGKYAEPVFECNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PGADIDPTQITFPGCICVKTPCLPGTCSCLRHGENYDDNSCLRDIGSGGKYAEPVFECNV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LCRCSDHCRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LCRCSDHCRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RIHLQTKSDSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RIHLQTKSDSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFLPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFLPF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 DSSLYCPVEKSNISCGNEKEPSMCGSAPSVFPSCKRLTLETMKMMLDKKQIRAIFLFEFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DSSLYCPVEKSNISCGNEKEPSMCGSAPSVFPSCKRLTLETMKMMLDKKQIRAIFLFEFK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 MGRKAAETTRNINNAFGPGTANERTVQWWFKKFCKGDESLEDEERSGRPSEVDNDQLRAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MGRKAAETTRNINNAFGPGTANERTVQWWFKKFCKGDESLEDEERSGRPSEVDNDQLRAI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 IEADPLTTTREVAEELNVNHSTVVRHLKQIGKVKKLDKWVPHELTENQKNRRFEVSSSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IEADPLTTTREVAEELNVNHSTVVRHLKQIGKVKKLDKWVPHELTENQKNRRFEVSSSLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 LRNHNEPFLDRIVTCDEKWILYDNRRRSAQWLDQEEAPKHFPKPILHPKKVMVTIWWSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LRNHNEPFLDRIVTCDEKWILYDNRRRSAQWLDQEEAPKHFPKPILHPKKVMVTIWWSAA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 GLIHYSFLNPGETITSEKYAQEIDEMNQKLQRLQLALVNRKGPILLHDNARPHVAQPTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GLIHYSFLNPGETITSEKYAQEIDEMNQKLQRLQLALVNRKGPILLHDNARPHVAQPTLQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 KLNELGYEVLPHPPYSPDLLPTNYHVFKHLNNFLQGKRFHNQQDAENAFQEFVESQSTDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KLNELGYEVLPHPPYSPDLLPTNYHVFKHLNNFLQGKRFHNQQDAENAFQEFVESQSTDF
610 620 630 640 650 660
670 680
pF1KE1 YATGINQLISRWQKCVDCNGSYFD
::::::::::::::::::::::::
NP_006 YATGINQLISRWQKCVDCNGSYFD
670 680
>>XP_016862521 (OMIM: 609834) PREDICTED: histone-lysine (479 aa)
initn: 3285 init1: 3285 opt: 3285 Z-score: 3256.9 bits: 612.5 E(85289): 1.1e-174
Smith-Waterman score: 3285; 100.0% identity (100.0% similar) in 479 aa overlap (206-684:1-479)
180 190 200 210 220 230
pF1KE1 SEVQRRIHLQTKSDSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPV
::::::::::::::::::::::::::::::
XP_016 METFVDPTYIGNIGRFLNHSCEPNLLMIPV
10 20 30
240 250 260 270 280 290
pF1KE1 RIDSMVPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIDSMVPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCT
40 50 60 70 80 90
300 310 320 330 340 350
pF1KE1 AFLPFDSSLYCPVEKSNISCGNEKEPSMCGSAPSVFPSCKRLTLETMKMMLDKKQIRAIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFLPFDSSLYCPVEKSNISCGNEKEPSMCGSAPSVFPSCKRLTLETMKMMLDKKQIRAIF
100 110 120 130 140 150
360 370 380 390 400 410
pF1KE1 LFEFKMGRKAAETTRNINNAFGPGTANERTVQWWFKKFCKGDESLEDEERSGRPSEVDND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFEFKMGRKAAETTRNINNAFGPGTANERTVQWWFKKFCKGDESLEDEERSGRPSEVDND
160 170 180 190 200 210
420 430 440 450 460 470
pF1KE1 QLRAIIEADPLTTTREVAEELNVNHSTVVRHLKQIGKVKKLDKWVPHELTENQKNRRFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLRAIIEADPLTTTREVAEELNVNHSTVVRHLKQIGKVKKLDKWVPHELTENQKNRRFEV
220 230 240 250 260 270
480 490 500 510 520 530
pF1KE1 SSSLILRNHNEPFLDRIVTCDEKWILYDNRRRSAQWLDQEEAPKHFPKPILHPKKVMVTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSLILRNHNEPFLDRIVTCDEKWILYDNRRRSAQWLDQEEAPKHFPKPILHPKKVMVTI
280 290 300 310 320 330
540 550 560 570 580 590
pF1KE1 WWSAAGLIHYSFLNPGETITSEKYAQEIDEMNQKLQRLQLALVNRKGPILLHDNARPHVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WWSAAGLIHYSFLNPGETITSEKYAQEIDEMNQKLQRLQLALVNRKGPILLHDNARPHVA
340 350 360 370 380 390
600 610 620 630 640 650
pF1KE1 QPTLQKLNELGYEVLPHPPYSPDLLPTNYHVFKHLNNFLQGKRFHNQQDAENAFQEFVES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPTLQKLNELGYEVLPHPPYSPDLLPTNYHVFKHLNNFLQGKRFHNQQDAENAFQEFVES
400 410 420 430 440 450
660 670 680
pF1KE1 QSTDFYATGINQLISRWQKCVDCNGSYFD
:::::::::::::::::::::::::::::
XP_016 QSTDFYATGINQLISRWQKCVDCNGSYFD
460 470
>>NP_001230652 (OMIM: 609834) histone-lysine N-methyltra (545 aa)
initn: 3812 init1: 2625 opt: 2640 Z-score: 2617.7 bits: 494.4 E(85289): 4.6e-139
Smith-Waterman score: 3538; 79.7% identity (79.7% similar) in 684 aa overlap (1-684:1-545)
10 20 30 40 50 60
pF1KE1 MFAEAAKTTRPCGMAEFKEKPEAPTEQLDVACGQENLPVGAWPPGAAPAPFQYTPDHVVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFAEAAKTTRPCGMAEFKEKPEAPTEQLDVACGQENLPVGAWPPGAAPAPFQYTPDHVVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PGADIDPTQITFPGCICVKTPCLPGTCSCLRHGENYDDNSCLRDIGSGGKYAEPVFECNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGADIDPTQITFPGCICVKTPCLPGTCSCLRHGENYDDNSCLRDIGSGGKYAEPVFECNV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LCRCSDHCRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQR
::::::::::::::::::::::::::::::::::::::::::
NP_001 LCRCSDHCRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKG------------------
130 140 150 160
190 200 210 220 230 240
pF1KE1 RIHLQTKSDSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSM
NP_001 ------------------------------------------------------------
250 260 270 280 290 300
pF1KE1 VPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFLPF
NP_001 ------------------------------------------------------------
310 320 330 340 350 360
pF1KE1 DSSLYCPVEKSNISCGNEKEPSMCGSAPSVFPSCKRLTLETMKMMLDKKQIRAIFLFEFK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -SSLYCPVEKSNISCGNEKEPSMCGSAPSVFPSCKRLTLETMKMMLDKKQIRAIFLFEFK
170 180 190 200 210 220
370 380 390 400 410 420
pF1KE1 MGRKAAETTRNINNAFGPGTANERTVQWWFKKFCKGDESLEDEERSGRPSEVDNDQLRAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRKAAETTRNINNAFGPGTANERTVQWWFKKFCKGDESLEDEERSGRPSEVDNDQLRAI
230 240 250 260 270 280
430 440 450 460 470 480
pF1KE1 IEADPLTTTREVAEELNVNHSTVVRHLKQIGKVKKLDKWVPHELTENQKNRRFEVSSSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEADPLTTTREVAEELNVNHSTVVRHLKQIGKVKKLDKWVPHELTENQKNRRFEVSSSLI
290 300 310 320 330 340
490 500 510 520 530 540
pF1KE1 LRNHNEPFLDRIVTCDEKWILYDNRRRSAQWLDQEEAPKHFPKPILHPKKVMVTIWWSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRNHNEPFLDRIVTCDEKWILYDNRRRSAQWLDQEEAPKHFPKPILHPKKVMVTIWWSAA
350 360 370 380 390 400
550 560 570 580 590 600
pF1KE1 GLIHYSFLNPGETITSEKYAQEIDEMNQKLQRLQLALVNRKGPILLHDNARPHVAQPTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLIHYSFLNPGETITSEKYAQEIDEMNQKLQRLQLALVNRKGPILLHDNARPHVAQPTLQ
410 420 430 440 450 460
610 620 630 640 650 660
pF1KE1 KLNELGYEVLPHPPYSPDLLPTNYHVFKHLNNFLQGKRFHNQQDAENAFQEFVESQSTDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLNELGYEVLPHPPYSPDLLPTNYHVFKHLNNFLQGKRFHNQQDAENAFQEFVESQSTDF
470 480 490 500 510 520
670 680
pF1KE1 YATGINQLISRWQKCVDCNGSYFD
::::::::::::::::::::::::
NP_001 YATGINQLISRWQKCVDCNGSYFD
530 540
>>NP_001307605 (OMIM: 609834) histone-lysine N-methyltra (406 aa)
initn: 2625 init1: 2625 opt: 2625 Z-score: 2604.6 bits: 491.6 E(85289): 2.4e-138
Smith-Waterman score: 2625; 100.0% identity (100.0% similar) in 383 aa overlap (302-684:24-406)
280 290 300 310 320 330
pF1KE1 SEDKERLDHGKLRKPCYCGAKSCTAFLPFDSSLYCPVEKSNISCGNEKEPSMCGSAPSVF
::::::::::::::::::::::::::::::
NP_001 MSRAARKTCRWARGPRGPRRRPSSSLYCPVEKSNISCGNEKEPSMCGSAPSVF
10 20 30 40 50
340 350 360 370 380 390
pF1KE1 PSCKRLTLETMKMMLDKKQIRAIFLFEFKMGRKAAETTRNINNAFGPGTANERTVQWWFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSCKRLTLETMKMMLDKKQIRAIFLFEFKMGRKAAETTRNINNAFGPGTANERTVQWWFK
60 70 80 90 100 110
400 410 420 430 440 450
pF1KE1 KFCKGDESLEDEERSGRPSEVDNDQLRAIIEADPLTTTREVAEELNVNHSTVVRHLKQIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFCKGDESLEDEERSGRPSEVDNDQLRAIIEADPLTTTREVAEELNVNHSTVVRHLKQIG
120 130 140 150 160 170
460 470 480 490 500 510
pF1KE1 KVKKLDKWVPHELTENQKNRRFEVSSSLILRNHNEPFLDRIVTCDEKWILYDNRRRSAQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVKKLDKWVPHELTENQKNRRFEVSSSLILRNHNEPFLDRIVTCDEKWILYDNRRRSAQW
180 190 200 210 220 230
520 530 540 550 560 570
pF1KE1 LDQEEAPKHFPKPILHPKKVMVTIWWSAAGLIHYSFLNPGETITSEKYAQEIDEMNQKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDQEEAPKHFPKPILHPKKVMVTIWWSAAGLIHYSFLNPGETITSEKYAQEIDEMNQKLQ
240 250 260 270 280 290
580 590 600 610 620 630
pF1KE1 RLQLALVNRKGPILLHDNARPHVAQPTLQKLNELGYEVLPHPPYSPDLLPTNYHVFKHLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLQLALVNRKGPILLHDNARPHVAQPTLQKLNELGYEVLPHPPYSPDLLPTNYHVFKHLN
300 310 320 330 340 350
640 650 660 670 680
pF1KE1 NFLQGKRFHNQQDAENAFQEFVESQSTDFYATGINQLISRWQKCVDCNGSYFD
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFLQGKRFHNQQDAENAFQEFVESQSTDFYATGINQLISRWQKCVDCNGSYFD
360 370 380 390 400
>>XP_006713355 (OMIM: 609834) PREDICTED: histone-lysine (448 aa)
initn: 2625 init1: 2625 opt: 2625 Z-score: 2604.0 bits: 491.6 E(85289): 2.6e-138
Smith-Waterman score: 2625; 100.0% identity (100.0% similar) in 383 aa overlap (302-684:66-448)
280 290 300 310 320 330
pF1KE1 SEDKERLDHGKLRKPCYCGAKSCTAFLPFDSSLYCPVEKSNISCGNEKEPSMCGSAPSVF
::::::::::::::::::::::::::::::
XP_006 NLAFCPVLSSELKEASRGESFTSLVSGVSHSSLYCPVEKSNISCGNEKEPSMCGSAPSVF
40 50 60 70 80 90
340 350 360 370 380 390
pF1KE1 PSCKRLTLETMKMMLDKKQIRAIFLFEFKMGRKAAETTRNINNAFGPGTANERTVQWWFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSCKRLTLETMKMMLDKKQIRAIFLFEFKMGRKAAETTRNINNAFGPGTANERTVQWWFK
100 110 120 130 140 150
400 410 420 430 440 450
pF1KE1 KFCKGDESLEDEERSGRPSEVDNDQLRAIIEADPLTTTREVAEELNVNHSTVVRHLKQIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KFCKGDESLEDEERSGRPSEVDNDQLRAIIEADPLTTTREVAEELNVNHSTVVRHLKQIG
160 170 180 190 200 210
460 470 480 490 500 510
pF1KE1 KVKKLDKWVPHELTENQKNRRFEVSSSLILRNHNEPFLDRIVTCDEKWILYDNRRRSAQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KVKKLDKWVPHELTENQKNRRFEVSSSLILRNHNEPFLDRIVTCDEKWILYDNRRRSAQW
220 230 240 250 260 270
520 530 540 550 560 570
pF1KE1 LDQEEAPKHFPKPILHPKKVMVTIWWSAAGLIHYSFLNPGETITSEKYAQEIDEMNQKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDQEEAPKHFPKPILHPKKVMVTIWWSAAGLIHYSFLNPGETITSEKYAQEIDEMNQKLQ
280 290 300 310 320 330
580 590 600 610 620 630
pF1KE1 RLQLALVNRKGPILLHDNARPHVAQPTLQKLNELGYEVLPHPPYSPDLLPTNYHVFKHLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLQLALVNRKGPILLHDNARPHVAQPTLQKLNELGYEVLPHPPYSPDLLPTNYHVFKHLN
340 350 360 370 380 390
640 650 660 670 680
pF1KE1 NFLQGKRFHNQQDAENAFQEFVESQSTDFYATGINQLISRWQKCVDCNGSYFD
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NFLQGKRFHNQQDAENAFQEFVESQSTDFYATGINQLISRWQKCVDCNGSYFD
400 410 420 430 440
>>NP_001307606 (OMIM: 609834) histone-lysine N-methyltra (428 aa)
initn: 2580 init1: 2580 opt: 2591 Z-score: 2570.6 bits: 485.4 E(85289): 1.9e-136
Smith-Waterman score: 2591; 96.0% identity (97.0% similar) in 398 aa overlap (287-684:33-428)
260 270 280 290 300 310
pF1KE1 ELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFLPFDSSLYCPVEKSNISCG
: :. :.:.. :: ::::::::
NP_001 SLFLNAMSCADAVTTAETEWSRKVYSSTSKCSRRIKKAGDFVPWN--LYRKEEKSNISCG
10 20 30 40 50 60
320 330 340 350 360 370
pF1KE1 NEKEPSMCGSAPSVFPSCKRLTLETMKMMLDKKQIRAIFLFEFKMGRKAAETTRNINNAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEKEPSMCGSAPSVFPSCKRLTLETMKMMLDKKQIRAIFLFEFKMGRKAAETTRNINNAF
70 80 90 100 110 120
380 390 400 410 420 430
pF1KE1 GPGTANERTVQWWFKKFCKGDESLEDEERSGRPSEVDNDQLRAIIEADPLTTTREVAEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPGTANERTVQWWFKKFCKGDESLEDEERSGRPSEVDNDQLRAIIEADPLTTTREVAEEL
130 140 150 160 170 180
440 450 460 470 480 490
pF1KE1 NVNHSTVVRHLKQIGKVKKLDKWVPHELTENQKNRRFEVSSSLILRNHNEPFLDRIVTCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVNHSTVVRHLKQIGKVKKLDKWVPHELTENQKNRRFEVSSSLILRNHNEPFLDRIVTCD
190 200 210 220 230 240
500 510 520 530 540 550
pF1KE1 EKWILYDNRRRSAQWLDQEEAPKHFPKPILHPKKVMVTIWWSAAGLIHYSFLNPGETITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKWILYDNRRRSAQWLDQEEAPKHFPKPILHPKKVMVTIWWSAAGLIHYSFLNPGETITS
250 260 270 280 290 300
560 570 580 590 600 610
pF1KE1 EKYAQEIDEMNQKLQRLQLALVNRKGPILLHDNARPHVAQPTLQKLNELGYEVLPHPPYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKYAQEIDEMNQKLQRLQLALVNRKGPILLHDNARPHVAQPTLQKLNELGYEVLPHPPYS
310 320 330 340 350 360
620 630 640 650 660 670
pF1KE1 PDLLPTNYHVFKHLNNFLQGKRFHNQQDAENAFQEFVESQSTDFYATGINQLISRWQKCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDLLPTNYHVFKHLNNFLQGKRFHNQQDAENAFQEFVESQSTDFYATGINQLISRWQKCV
370 380 390 400 410 420
680
pF1KE1 DCNGSYFD
::::::::
NP_001 DCNGSYFD
>>XP_006713357 (OMIM: 609834) PREDICTED: histone-lysine (428 aa)
initn: 2580 init1: 2580 opt: 2591 Z-score: 2570.6 bits: 485.4 E(85289): 1.9e-136
Smith-Waterman score: 2591; 96.0% identity (97.0% similar) in 398 aa overlap (287-684:33-428)
260 270 280 290 300 310
pF1KE1 ELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFLPFDSSLYCPVEKSNISCG
: :. :.:.. :: ::::::::
XP_006 SLFLNAMSCADAVTTAETEWSRKVYSSTSKCSRRIKKAGDFVPWN--LYRKEEKSNISCG
10 20 30 40 50 60
320 330 340 350 360 370
pF1KE1 NEKEPSMCGSAPSVFPSCKRLTLETMKMMLDKKQIRAIFLFEFKMGRKAAETTRNINNAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NEKEPSMCGSAPSVFPSCKRLTLETMKMMLDKKQIRAIFLFEFKMGRKAAETTRNINNAF
70 80 90 100 110 120
380 390 400 410 420 430
pF1KE1 GPGTANERTVQWWFKKFCKGDESLEDEERSGRPSEVDNDQLRAIIEADPLTTTREVAEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPGTANERTVQWWFKKFCKGDESLEDEERSGRPSEVDNDQLRAIIEADPLTTTREVAEEL
130 140 150 160 170 180
440 450 460 470 480 490
pF1KE1 NVNHSTVVRHLKQIGKVKKLDKWVPHELTENQKNRRFEVSSSLILRNHNEPFLDRIVTCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NVNHSTVVRHLKQIGKVKKLDKWVPHELTENQKNRRFEVSSSLILRNHNEPFLDRIVTCD
190 200 210 220 230 240
500 510 520 530 540 550
pF1KE1 EKWILYDNRRRSAQWLDQEEAPKHFPKPILHPKKVMVTIWWSAAGLIHYSFLNPGETITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKWILYDNRRRSAQWLDQEEAPKHFPKPILHPKKVMVTIWWSAAGLIHYSFLNPGETITS
250 260 270 280 290 300
560 570 580 590 600 610
pF1KE1 EKYAQEIDEMNQKLQRLQLALVNRKGPILLHDNARPHVAQPTLQKLNELGYEVLPHPPYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKYAQEIDEMNQKLQRLQLALVNRKGPILLHDNARPHVAQPTLQKLNELGYEVLPHPPYS
310 320 330 340 350 360
620 630 640 650 660 670
pF1KE1 PDLLPTNYHVFKHLNNFLQGKRFHNQQDAENAFQEFVESQSTDFYATGINQLISRWQKCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDLLPTNYHVFKHLNNFLQGKRFHNQQDAENAFQEFVESQSTDFYATGINQLISRWQKCV
370 380 390 400 410 420
680
pF1KE1 DCNGSYFD
::::::::
XP_006 DCNGSYFD
>>NP_001263254 (OMIM: 609834) histone-lysine N-methyltra (365 aa)
initn: 2418 init1: 2418 opt: 2423 Z-score: 2405.3 bits: 454.6 E(85289): 3.1e-127
Smith-Waterman score: 2423; 98.0% identity (99.4% similar) in 349 aa overlap (1-349:1-348)
10 20 30 40 50 60
pF1KE1 MFAEAAKTTRPCGMAEFKEKPEAPTEQLDVACGQENLPVGAWPPGAAPAPFQYTPDHVVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFAEAAKTTRPCGMAEFKEKPEAPTEQLDVACGQENLPVGAWPPGAAPAPFQYTPDHVVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PGADIDPTQITFPGCICVKTPCLPGTCSCLRHGENYDDNSCLRDIGSGGKYAEPVFECNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGADIDPTQITFPGCICVKTPCLPGTCSCLRHGENYDDNSCLRDIGSGGKYAEPVFECNV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LCRCSDHCRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCRCSDHCRNRVVQKGLQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RIHLQTKSDSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIHLQTKSDSNYIIAIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFLPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFLPF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 DSSLYCPVEKSNISCGNEKEPSMCGSAPSVFPSCKRLTLETMKMMLDKKQIRAIFLFEFK
:::::::::::::::::::::::::::::::::::::::: .... ::.
NP_001 DSSLYCPVEKSNISCGNEKEPSMCGSAPSVFPSCKRLTLE-VSLFSDKQLAPPYSGRQWL
310 320 330 340 350
370 380 390 400 410 420
pF1KE1 MGRKAAETTRNINNAFGPGTANERTVQWWFKKFCKGDESLEDEERSGRPSEVDNDQLRAI
NP_001 ASFTSA
360
>>NP_001307607 (OMIM: 609834) histone-lysine N-methyltra (396 aa)
initn: 2354 init1: 2354 opt: 2397 Z-score: 2379.1 bits: 449.8 E(85289): 8.9e-126
Smith-Waterman score: 2397; 93.4% identity (96.3% similar) in 378 aa overlap (307-684:24-396)
280 290 300 310 320 330
pF1KE1 RLDHGKLRKPCYCGAKSCTAFLPFDSSLYCPVEKSNISCGNEKEPSMCGSAPSVFPSCKR
:.:. ...::.:. : :. : :.
NP_001 MFAEAAKTTRPCGMAEFKEKPEAPTEQLDVACGQENLP--VGAWP---PGAAP
10 20 30 40
340 350 360 370 380 390
pF1KE1 LTLETMKMMLDKKQIRAIFLFEFKMGRKAAETTRNINNAFGPGTANERTVQWWFKKFCKG
..::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APFQTMKMMLDKKQIRAIFLFEFKMGRKAAETTRNINNAFGPGTANERTVQWWFKKFCKG
50 60 70 80 90 100
400 410 420 430 440 450
pF1KE1 DESLEDEERSGRPSEVDNDQLRAIIEADPLTTTREVAEELNVNHSTVVRHLKQIGKVKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DESLEDEERSGRPSEVDNDQLRAIIEADPLTTTREVAEELNVNHSTVVRHLKQIGKVKKL
110 120 130 140 150 160
460 470 480 490 500 510
pF1KE1 DKWVPHELTENQKNRRFEVSSSLILRNHNEPFLDRIVTCDEKWILYDNRRRSAQWLDQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKWVPHELTENQKNRRFEVSSSLILRNHNEPFLDRIVTCDEKWILYDNRRRSAQWLDQEE
170 180 190 200 210 220
520 530 540 550 560 570
pF1KE1 APKHFPKPILHPKKVMVTIWWSAAGLIHYSFLNPGETITSEKYAQEIDEMNQKLQRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APKHFPKPILHPKKVMVTIWWSAAGLIHYSFLNPGETITSEKYAQEIDEMNQKLQRLQLA
230 240 250 260 270 280
580 590 600 610 620 630
pF1KE1 LVNRKGPILLHDNARPHVAQPTLQKLNELGYEVLPHPPYSPDLLPTNYHVFKHLNNFLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVNRKGPILLHDNARPHVAQPTLQKLNELGYEVLPHPPYSPDLLPTNYHVFKHLNNFLQG
290 300 310 320 330 340
640 650 660 670 680
pF1KE1 KRFHNQQDAENAFQEFVESQSTDFYATGINQLISRWQKCVDCNGSYFD
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRFHNQQDAENAFQEFVESQSTDFYATGINQLISRWQKCVDCNGSYFD
350 360 370 380 390
>>XP_011544282 (OMIM: 605847) PREDICTED: B-cell CLL/lymp (293 aa)
initn: 511 init1: 511 opt: 527 Z-score: 529.9 bits: 107.2 E(85289): 8.9e-23
Smith-Waterman score: 527; 65.1% identity (82.9% similar) in 129 aa overlap (309-437:148-273)
280 290 300 310 320 330
pF1KE1 DHGKLRKPCYCGAKSCTAFLPFDSSLYCPVEKSNISCGNEKEPSMCGSAPSVFPSCKRLT
. ..:. :. :: : . : : . :
XP_011 TPQPSRPVSPAGPPEGVPEEAQPPRLGQERDPGGITAGSTDEPPMLTKEEPV-P--ELLE
120 130 140 150 160 170
340 350 360 370 380 390
pF1KE1 LETMKMMLDKKQIRAIFLFEFKMGRKAAETTRNINNAFGPGTANERTVQWWFKKFCKGDE
:::.::::::::.::::::.:::.::.:: :::::..:::::::. :::::::::: :.
XP_011 AETMEMMLDKKQIQAIFLFELKMGHKAVETLRNINNTLGPGTANEHIVQWWFKKFCKEDK
180 190 200 210 220 230
400 410 420 430 440 450
pF1KE1 SLEDEERSGRPSEVDNDQLRAIIEADPLTTTREVAEELNVNHSTVVRHLKQIGKVKKLDK
:::::..: :::::::::.:.:::::. ::.:::.:::
XP_011 SLEDEKHSVWPSEVDNDQLKALIEADPVKTTQEVAQELNHRPFYGRLAFEANWKGEKAQ
240 250 260 270 280 290
460 470 480 490 500 510
pF1KE1 WVPHELTENQKNRRFEVSSSLILRNHNEPFLDRIVTCDEKWILYDNRRRSAQWLDQEEAP
684 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:58:06 2016 done: Mon Nov 7 03:58:08 2016
Total Scan time: 10.970 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]