Result of FASTA (omim) for
pFN21AE1147
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1147, 462 aa
1>>>pF1KE1147 462 - 462 aa - 462 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.3636+/-0.000358; mu= -4.1965+/- 0.022
mean_var=255.2414+/-54.292, 0's: 0 Z-trim(122.6): 18 B-trim: 2789 in 2/60
Lambda= 0.080278
statistics sampled from 40872 (40936) to 40872 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.779), E-opt: 0.2 (0.48), width: 16
Scan time: 11.450
The best scores are: opt bits E(85289)
NP_001135943 (OMIM: 611355) integrator complex sub ( 462) 2958 355.3 2e-97
XP_011530447 (OMIM: 611355) PREDICTED: integrator ( 462) 2958 355.3 2e-97
XP_005263205 (OMIM: 611355) PREDICTED: integrator ( 462) 2958 355.3 2e-97
XP_011530445 (OMIM: 611355) PREDICTED: integrator ( 462) 2958 355.3 2e-97
NP_065128 (OMIM: 611355) integrator complex subuni ( 462) 2958 355.3 2e-97
>>NP_001135943 (OMIM: 611355) integrator complex subunit (462 aa)
initn: 2958 init1: 2958 opt: 2958 Z-score: 1870.0 bits: 355.3 E(85289): 2e-97
Smith-Waterman score: 2958; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE1 MAATVNLELDPIFLKALGFLHSKSKDSAEKLKALLDESLARGIDSSYRPSQKDVEPPKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAATVNLELDPIFLKALGFLHSKSKDSAEKLKALLDESLARGIDSSYRPSQKDVEPPKIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 STKNISIKQEPKISSSLPSGNNNGKVLTTEKVKKEAEKRPADKMKSDITEGVDIPKKPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STKNISIKQEPKISSSLPSGNNNGKVLTTEKVKKEAEKRPADKMKSDITEGVDIPKKPRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKPETQSSPITVQSSKDLPMADLSSFEETSADDFAMEMGLACVVCRQMMVASGNQLVECQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKPETQSSPITVQSSKDLPMADLSSFEETSADDFAMEMGLACVVCRQMMVASGNQLVECQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ECHNLYHRDCHKPQVTDKEANDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPAVVSVTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECHNLYHRDCHKPQVTDKEANDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPAVVSVTPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VKDPLVKKPETKLKQETTFLAFKRTEVKTSTVISGNSSSASVSSSVTSGLTGWAAFAAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKDPLVKKPETKLKQETTFLAFKRTEVKTSTVISGNSSSASVSSSVTSGLTGWAAFAAKT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 SSAGPSTAKLSSTTQNNTGKPATSSANQKPVGLTGLATSSKGGIGSKIGSNNSTTPTVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSAGPSTAKLSSTTQNNTGKPATSSANQKPVGLTGLATSSKGGIGSKIGSNNSTTPTVPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 KPPPPLTLGKTGLSRSVSCDNVSKVGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPPPPLTLGKTGLSRSVSCDNVSKVGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSKT
370 380 390 400 410 420
430 440 450 460
pF1KE1 TSESSSSPSASLKGPTSQESQLNAMKRLQMVKKKAAQKKLKK
::::::::::::::::::::::::::::::::::::::::::
NP_001 TSESSSSPSASLKGPTSQESQLNAMKRLQMVKKKAAQKKLKK
430 440 450 460
>>XP_011530447 (OMIM: 611355) PREDICTED: integrator comp (462 aa)
initn: 2958 init1: 2958 opt: 2958 Z-score: 1870.0 bits: 355.3 E(85289): 2e-97
Smith-Waterman score: 2958; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE1 MAATVNLELDPIFLKALGFLHSKSKDSAEKLKALLDESLARGIDSSYRPSQKDVEPPKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAATVNLELDPIFLKALGFLHSKSKDSAEKLKALLDESLARGIDSSYRPSQKDVEPPKIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 STKNISIKQEPKISSSLPSGNNNGKVLTTEKVKKEAEKRPADKMKSDITEGVDIPKKPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STKNISIKQEPKISSSLPSGNNNGKVLTTEKVKKEAEKRPADKMKSDITEGVDIPKKPRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKPETQSSPITVQSSKDLPMADLSSFEETSADDFAMEMGLACVVCRQMMVASGNQLVECQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKPETQSSPITVQSSKDLPMADLSSFEETSADDFAMEMGLACVVCRQMMVASGNQLVECQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ECHNLYHRDCHKPQVTDKEANDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPAVVSVTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECHNLYHRDCHKPQVTDKEANDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPAVVSVTPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VKDPLVKKPETKLKQETTFLAFKRTEVKTSTVISGNSSSASVSSSVTSGLTGWAAFAAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKDPLVKKPETKLKQETTFLAFKRTEVKTSTVISGNSSSASVSSSVTSGLTGWAAFAAKT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 SSAGPSTAKLSSTTQNNTGKPATSSANQKPVGLTGLATSSKGGIGSKIGSNNSTTPTVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSAGPSTAKLSSTTQNNTGKPATSSANQKPVGLTGLATSSKGGIGSKIGSNNSTTPTVPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 KPPPPLTLGKTGLSRSVSCDNVSKVGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPPPPLTLGKTGLSRSVSCDNVSKVGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSKT
370 380 390 400 410 420
430 440 450 460
pF1KE1 TSESSSSPSASLKGPTSQESQLNAMKRLQMVKKKAAQKKLKK
::::::::::::::::::::::::::::::::::::::::::
XP_011 TSESSSSPSASLKGPTSQESQLNAMKRLQMVKKKAAQKKLKK
430 440 450 460
>>XP_005263205 (OMIM: 611355) PREDICTED: integrator comp (462 aa)
initn: 2958 init1: 2958 opt: 2958 Z-score: 1870.0 bits: 355.3 E(85289): 2e-97
Smith-Waterman score: 2958; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE1 MAATVNLELDPIFLKALGFLHSKSKDSAEKLKALLDESLARGIDSSYRPSQKDVEPPKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAATVNLELDPIFLKALGFLHSKSKDSAEKLKALLDESLARGIDSSYRPSQKDVEPPKIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 STKNISIKQEPKISSSLPSGNNNGKVLTTEKVKKEAEKRPADKMKSDITEGVDIPKKPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STKNISIKQEPKISSSLPSGNNNGKVLTTEKVKKEAEKRPADKMKSDITEGVDIPKKPRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKPETQSSPITVQSSKDLPMADLSSFEETSADDFAMEMGLACVVCRQMMVASGNQLVECQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKPETQSSPITVQSSKDLPMADLSSFEETSADDFAMEMGLACVVCRQMMVASGNQLVECQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ECHNLYHRDCHKPQVTDKEANDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPAVVSVTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECHNLYHRDCHKPQVTDKEANDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPAVVSVTPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VKDPLVKKPETKLKQETTFLAFKRTEVKTSTVISGNSSSASVSSSVTSGLTGWAAFAAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKDPLVKKPETKLKQETTFLAFKRTEVKTSTVISGNSSSASVSSSVTSGLTGWAAFAAKT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 SSAGPSTAKLSSTTQNNTGKPATSSANQKPVGLTGLATSSKGGIGSKIGSNNSTTPTVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSAGPSTAKLSSTTQNNTGKPATSSANQKPVGLTGLATSSKGGIGSKIGSNNSTTPTVPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 KPPPPLTLGKTGLSRSVSCDNVSKVGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPPPPLTLGKTGLSRSVSCDNVSKVGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSKT
370 380 390 400 410 420
430 440 450 460
pF1KE1 TSESSSSPSASLKGPTSQESQLNAMKRLQMVKKKAAQKKLKK
::::::::::::::::::::::::::::::::::::::::::
XP_005 TSESSSSPSASLKGPTSQESQLNAMKRLQMVKKKAAQKKLKK
430 440 450 460
>>XP_011530445 (OMIM: 611355) PREDICTED: integrator comp (462 aa)
initn: 2958 init1: 2958 opt: 2958 Z-score: 1870.0 bits: 355.3 E(85289): 2e-97
Smith-Waterman score: 2958; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE1 MAATVNLELDPIFLKALGFLHSKSKDSAEKLKALLDESLARGIDSSYRPSQKDVEPPKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAATVNLELDPIFLKALGFLHSKSKDSAEKLKALLDESLARGIDSSYRPSQKDVEPPKIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 STKNISIKQEPKISSSLPSGNNNGKVLTTEKVKKEAEKRPADKMKSDITEGVDIPKKPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STKNISIKQEPKISSSLPSGNNNGKVLTTEKVKKEAEKRPADKMKSDITEGVDIPKKPRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKPETQSSPITVQSSKDLPMADLSSFEETSADDFAMEMGLACVVCRQMMVASGNQLVECQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKPETQSSPITVQSSKDLPMADLSSFEETSADDFAMEMGLACVVCRQMMVASGNQLVECQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ECHNLYHRDCHKPQVTDKEANDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPAVVSVTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECHNLYHRDCHKPQVTDKEANDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPAVVSVTPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VKDPLVKKPETKLKQETTFLAFKRTEVKTSTVISGNSSSASVSSSVTSGLTGWAAFAAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKDPLVKKPETKLKQETTFLAFKRTEVKTSTVISGNSSSASVSSSVTSGLTGWAAFAAKT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 SSAGPSTAKLSSTTQNNTGKPATSSANQKPVGLTGLATSSKGGIGSKIGSNNSTTPTVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSAGPSTAKLSSTTQNNTGKPATSSANQKPVGLTGLATSSKGGIGSKIGSNNSTTPTVPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 KPPPPLTLGKTGLSRSVSCDNVSKVGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPPPPLTLGKTGLSRSVSCDNVSKVGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSKT
370 380 390 400 410 420
430 440 450 460
pF1KE1 TSESSSSPSASLKGPTSQESQLNAMKRLQMVKKKAAQKKLKK
::::::::::::::::::::::::::::::::::::::::::
XP_011 TSESSSSPSASLKGPTSQESQLNAMKRLQMVKKKAAQKKLKK
430 440 450 460
>>NP_065128 (OMIM: 611355) integrator complex subunit 12 (462 aa)
initn: 2958 init1: 2958 opt: 2958 Z-score: 1870.0 bits: 355.3 E(85289): 2e-97
Smith-Waterman score: 2958; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE1 MAATVNLELDPIFLKALGFLHSKSKDSAEKLKALLDESLARGIDSSYRPSQKDVEPPKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MAATVNLELDPIFLKALGFLHSKSKDSAEKLKALLDESLARGIDSSYRPSQKDVEPPKIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 STKNISIKQEPKISSSLPSGNNNGKVLTTEKVKKEAEKRPADKMKSDITEGVDIPKKPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 STKNISIKQEPKISSSLPSGNNNGKVLTTEKVKKEAEKRPADKMKSDITEGVDIPKKPRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKPETQSSPITVQSSKDLPMADLSSFEETSADDFAMEMGLACVVCRQMMVASGNQLVECQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EKPETQSSPITVQSSKDLPMADLSSFEETSADDFAMEMGLACVVCRQMMVASGNQLVECQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ECHNLYHRDCHKPQVTDKEANDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPAVVSVTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ECHNLYHRDCHKPQVTDKEANDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPAVVSVTPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VKDPLVKKPETKLKQETTFLAFKRTEVKTSTVISGNSSSASVSSSVTSGLTGWAAFAAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VKDPLVKKPETKLKQETTFLAFKRTEVKTSTVISGNSSSASVSSSVTSGLTGWAAFAAKT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 SSAGPSTAKLSSTTQNNTGKPATSSANQKPVGLTGLATSSKGGIGSKIGSNNSTTPTVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SSAGPSTAKLSSTTQNNTGKPATSSANQKPVGLTGLATSSKGGIGSKIGSNNSTTPTVPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 KPPPPLTLGKTGLSRSVSCDNVSKVGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KPPPPLTLGKTGLSRSVSCDNVSKVGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSKT
370 380 390 400 410 420
430 440 450 460
pF1KE1 TSESSSSPSASLKGPTSQESQLNAMKRLQMVKKKAAQKKLKK
::::::::::::::::::::::::::::::::::::::::::
NP_065 TSESSSSPSASLKGPTSQESQLNAMKRLQMVKKKAAQKKLKK
430 440 450 460
462 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:20:27 2016 done: Sun Nov 6 17:20:28 2016
Total Scan time: 11.450 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]