Result of FASTA (omim) for
pFN21AE1139
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1139, 397 aa
1>>>pF1KE1139 397 - 397 aa - 397 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2081+/-0.000488; mu= 8.0760+/- 0.030
mean_var=145.4065+/-31.252, 0's: 0 Z-trim(113.6): 255 B-trim: 855 in 1/54
Lambda= 0.106361
statistics sampled from 22638 (22995) to 22638 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.27), width: 16
Scan time: 8.420
The best scores are: opt bits E(85289)
NP_059430 (OMIM: 182115) cytohesin-1 isoform 2 [Ho ( 397) 2670 421.8 1.4e-117
NP_004753 (OMIM: 182115) cytohesin-1 isoform 1 [Ho ( 398) 2658 420.0 5e-117
XP_016880825 (OMIM: 182115) PREDICTED: cytohesin-1 ( 399) 2630 415.7 9.8e-116
XP_016880826 (OMIM: 182115) PREDICTED: cytohesin-1 ( 380) 2518 398.5 1.4e-110
XP_016880827 (OMIM: 182115) PREDICTED: cytohesin-1 ( 338) 2305 365.8 8.9e-101
XP_011523779 (OMIM: 182115) PREDICTED: cytohesin-1 ( 339) 2293 363.9 3.2e-100
NP_001278947 (OMIM: 182115) cytohesin-1 isoform 3 ( 339) 2293 363.9 3.2e-100
NP_001278948 (OMIM: 182115) cytohesin-1 isoform 3 ( 339) 2293 363.9 3.2e-100
NP_004218 (OMIM: 605081) cytohesin-3 [Homo sapiens ( 399) 2279 361.8 1.6e-99
NP_004219 (OMIM: 602488) cytohesin-2 isoform 2 [Ho ( 399) 2275 361.2 2.5e-99
NP_059431 (OMIM: 602488) cytohesin-2 isoform 1 [Ho ( 400) 2263 359.4 8.8e-99
XP_006723535 (OMIM: 602488) PREDICTED: cytohesin-2 ( 421) 2259 358.8 1.4e-98
XP_011523778 (OMIM: 182115) PREDICTED: cytohesin-1 ( 322) 2141 340.6 3.2e-93
XP_011523777 (OMIM: 182115) PREDICTED: cytohesin-1 ( 322) 2141 340.6 3.2e-93
XP_006723536 (OMIM: 602488) PREDICTED: cytohesin-2 ( 394) 2131 339.1 1.1e-92
NP_037517 (OMIM: 606514) cytohesin-4 isoform 1 [Ho ( 394) 1927 307.8 2.9e-83
NP_001304953 (OMIM: 606514) cytohesin-4 isoform 2 ( 337) 1787 286.3 7.5e-77
XP_011528449 (OMIM: 606514) PREDICTED: cytohesin-4 ( 337) 1787 286.3 7.5e-77
XP_011523780 (OMIM: 182115) PREDICTED: cytohesin-1 ( 235) 1598 257.2 3.1e-68
XP_011528450 (OMIM: 606514) PREDICTED: cytohesin-4 ( 211) 864 144.5 2.3e-34
XP_011515744 (OMIM: 604141) PREDICTED: brefeldin A (1649) 655 113.1 5e-24
XP_005251193 (OMIM: 604141) PREDICTED: brefeldin A (1800) 655 113.1 5.3e-24
XP_005251192 (OMIM: 604141) PREDICTED: brefeldin A (1843) 655 113.2 5.4e-24
NP_006412 (OMIM: 604141) brefeldin A-inhibited gua (1849) 655 113.2 5.4e-24
XP_005251191 (OMIM: 604141) PREDICTED: brefeldin A (1849) 655 113.2 5.4e-24
XP_005260309 (OMIM: 605371,608097) PREDICTED: bref (1784) 639 110.7 2.9e-23
NP_006411 (OMIM: 605371,608097) brefeldin A-inhibi (1785) 639 110.7 2.9e-23
NP_001317548 (OMIM: 610166) IQ motif and SEC7 doma ( 814) 542 95.5 4.8e-19
XP_011532617 (OMIM: 610166) PREDICTED: IQ motif an ( 814) 542 95.5 4.8e-19
NP_055684 (OMIM: 610166) IQ motif and SEC7 domain- ( 963) 542 95.6 5.4e-19
XP_011532615 (OMIM: 610166) PREDICTED: IQ motif an (1006) 542 95.6 5.6e-19
XP_011532616 (OMIM: 610166) PREDICTED: IQ motif an (1006) 542 95.6 5.6e-19
XP_011532613 (OMIM: 610166) PREDICTED: IQ motif an (1006) 542 95.6 5.6e-19
XP_011532614 (OMIM: 610166) PREDICTED: IQ motif an (1006) 542 95.6 5.6e-19
XP_011532612 (OMIM: 610166) PREDICTED: IQ motif an (1030) 542 95.6 5.7e-19
NP_001127854 (OMIM: 610166) IQ motif and SEC7 doma (1114) 542 95.6 6.1e-19
XP_011532610 (OMIM: 610166) PREDICTED: IQ motif an (1128) 542 95.7 6.1e-19
XP_011532609 (OMIM: 610166) PREDICTED: IQ motif an (1129) 542 95.7 6.1e-19
XP_011532608 (OMIM: 610166) PREDICTED: IQ motif an (1129) 542 95.7 6.1e-19
XP_011532607 (OMIM: 610166) PREDICTED: IQ motif an (1132) 542 95.7 6.2e-19
XP_016863071 (OMIM: 610166) PREDICTED: IQ motif an (1207) 542 95.7 6.5e-19
XP_016863070 (OMIM: 610166) PREDICTED: IQ motif an (1212) 542 95.7 6.5e-19
XP_011532606 (OMIM: 610166) PREDICTED: IQ motif an (1222) 542 95.7 6.5e-19
NP_056047 (OMIM: 612118) IQ motif and SEC7 domain- ( 759) 526 93.1 2.5e-18
XP_011519263 (OMIM: 612118) PREDICTED: IQ motif an ( 879) 526 93.1 2.8e-18
XP_016874799 (OMIM: 612118) PREDICTED: IQ motif an (1041) 526 93.2 3.2e-18
XP_016874800 (OMIM: 612118) PREDICTED: IQ motif an (1041) 526 93.2 3.2e-18
XP_011519261 (OMIM: 612118) PREDICTED: IQ motif an (1062) 526 93.2 3.2e-18
XP_011519262 (OMIM: 612118) PREDICTED: IQ motif an (1062) 526 93.2 3.2e-18
XP_011519260 (OMIM: 612118) PREDICTED: IQ motif an (1063) 526 93.2 3.2e-18
>>NP_059430 (OMIM: 182115) cytohesin-1 isoform 2 [Homo s (397 aa)
initn: 2670 init1: 2670 opt: 2670 Z-score: 2232.0 bits: 421.8 E(85289): 1.4e-117
Smith-Waterman score: 2670; 100.0% identity (100.0% similar) in 397 aa overlap (1-397:1-397)
10 20 30 40 50 60
pF1KE1 MEEDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEERKNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 MEEDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEERKNM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 QRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 QRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 EFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 QSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 QSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 NEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 NEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 RGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 RGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPT
310 320 330 340 350 360
370 380 390
pF1KE1 PEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH
:::::::::::::::::::::::::::::::::::::
NP_059 PEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH
370 380 390
>>NP_004753 (OMIM: 182115) cytohesin-1 isoform 1 [Homo s (398 aa)
initn: 1817 init1: 1817 opt: 2658 Z-score: 2222.0 bits: 420.0 E(85289): 5e-117
Smith-Waterman score: 2658; 99.7% identity (99.7% similar) in 398 aa overlap (1-397:1-398)
10 20 30 40 50 60
pF1KE1 MEEDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEERKNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MEEDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEERKNM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 QRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 QSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIK
190 200 210 220 230 240
250 260 270 280 290
pF1KE1 NEPFKIPEDDGNDLTHTFFNPDREGWLLKLGG-RVKTWKRRWFILTDNCLYYFEYTTDKE
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
NP_004 NEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE1 PRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAP
310 320 330 340 350 360
360 370 380 390
pF1KE1 TPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH
::::::::::::::::::::::::::::::::::::::
NP_004 TPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH
370 380 390
>>XP_016880825 (OMIM: 182115) PREDICTED: cytohesin-1 iso (399 aa)
initn: 2625 init1: 2625 opt: 2630 Z-score: 2198.8 bits: 415.7 E(85289): 9.8e-116
Smith-Waterman score: 2630; 99.2% identity (99.5% similar) in 396 aa overlap (2-397:6-399)
10 20 30 40 50
pF1KE1 MEEDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEE
::.: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVLKTEEED--VPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEE
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 RKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 GERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 NGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 DKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRI
300 310 320 330 340 350
360 370 380 390
pF1KE1 SAPTPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH
:::::::::::::::::::::::::::::::::::::::::
XP_016 SAPTPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH
360 370 380 390
>>XP_016880826 (OMIM: 182115) PREDICTED: cytohesin-1 iso (380 aa)
initn: 2518 init1: 2518 opt: 2518 Z-score: 2106.2 bits: 398.5 E(85289): 1.4e-110
Smith-Waterman score: 2518; 99.2% identity (99.5% similar) in 376 aa overlap (1-376:1-376)
10 20 30 40 50 60
pF1KE1 MEEDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEERKNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEERKNM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 QRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 QSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 NEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 RGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPT
310 320 330 340 350 360
370 380 390
pF1KE1 PEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH
:::::::::::: .:
XP_016 PEEKEEWIKCIKFQVSPGEP
370 380
>>XP_016880827 (OMIM: 182115) PREDICTED: cytohesin-1 iso (338 aa)
initn: 2305 init1: 2305 opt: 2305 Z-score: 1930.2 bits: 365.8 E(85289): 8.9e-101
Smith-Waterman score: 2305; 100.0% identity (100.0% similar) in 338 aa overlap (60-397:1-338)
30 40 50 60 70 80
pF1KE1 LLADIQRLKDEIAEVANEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDL
::::::::::::::::::::::::::::::
XP_016 MQRNKQVAMGRKKFNMDPKKGIQFLIENDL
10 20 30
90 100 110 120 130 140
pF1KE1 LKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 WSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKP
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE1 TVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLK
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE1 LGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPD
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE1 NKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARKK
280 290 300 310 320 330
390
pF1KE1 KVSSTKRH
::::::::
XP_016 KVSSTKRH
>>XP_011523779 (OMIM: 182115) PREDICTED: cytohesin-1 iso (339 aa)
initn: 1452 init1: 1452 opt: 2293 Z-score: 1920.3 bits: 363.9 E(85289): 3.2e-100
Smith-Waterman score: 2293; 99.7% identity (99.7% similar) in 339 aa overlap (60-397:1-339)
30 40 50 60 70 80
pF1KE1 LLADIQRLKDEIAEVANEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDL
::::::::::::::::::::::::::::::
XP_011 MQRNKQVAMGRKKFNMDPKKGIQFLIENDL
10 20 30
90 100 110 120 130 140
pF1KE1 LKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 WSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKP
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE1 TVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLK
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE1 LGG-RVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIP
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIP
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE1 DNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARK
280 290 300 310 320 330
390
pF1KE1 KKVSSTKRH
:::::::::
XP_011 KKVSSTKRH
>>NP_001278947 (OMIM: 182115) cytohesin-1 isoform 3 [Hom (339 aa)
initn: 1452 init1: 1452 opt: 2293 Z-score: 1920.3 bits: 363.9 E(85289): 3.2e-100
Smith-Waterman score: 2293; 99.7% identity (99.7% similar) in 339 aa overlap (60-397:1-339)
30 40 50 60 70 80
pF1KE1 LLADIQRLKDEIAEVANEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDL
::::::::::::::::::::::::::::::
NP_001 MQRNKQVAMGRKKFNMDPKKGIQFLIENDL
10 20 30
90 100 110 120 130 140
pF1KE1 LKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 WSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKP
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE1 TVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLK
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE1 LGG-RVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIP
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIP
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE1 DNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARK
280 290 300 310 320 330
390
pF1KE1 KKVSSTKRH
:::::::::
NP_001 KKVSSTKRH
>>NP_001278948 (OMIM: 182115) cytohesin-1 isoform 3 [Hom (339 aa)
initn: 1452 init1: 1452 opt: 2293 Z-score: 1920.3 bits: 363.9 E(85289): 3.2e-100
Smith-Waterman score: 2293; 99.7% identity (99.7% similar) in 339 aa overlap (60-397:1-339)
30 40 50 60 70 80
pF1KE1 LLADIQRLKDEIAEVANEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDL
::::::::::::::::::::::::::::::
NP_001 MQRNKQVAMGRKKFNMDPKKGIQFLIENDL
10 20 30
90 100 110 120 130 140
pF1KE1 LKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 WSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKP
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE1 TVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLK
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE1 LGG-RVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIP
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIP
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE1 DNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARK
280 290 300 310 320 330
390
pF1KE1 KKVSSTKRH
:::::::::
NP_001 KKVSSTKRH
>>NP_004218 (OMIM: 605081) cytohesin-3 [Homo sapiens] (399 aa)
initn: 2330 init1: 2278 opt: 2279 Z-score: 1907.7 bits: 361.8 E(85289): 1.6e-99
Smith-Waterman score: 2279; 84.2% identity (94.0% similar) in 399 aa overlap (1-395:1-399)
10 20 30 40 50
pF1KE1 MEEDDSY----VPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEE
:.:: . :: ::. :::.:: .:::::.::. ::.::: ::::: .::.:: :.::
NP_004 MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 RKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYL
:. :::::.::::::::::::::::::::::::... ::.:::::::::::::.:::::
NP_004 SKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 GERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCN
::::::::.::.::::::::.::::::::::::::::::::::::::::::::.::: ::
NP_004 GERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 NGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLY
::::::::::::::::::::::::: ::.::::.:::::::::::.:::::::::::::
NP_004 PGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTT
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE1 DKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRI
:::::::::::::::::::: .:::::::: :..: :::::::::::::::::::.::::
NP_004 DKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRI
310 320 330 340 350 360
360 370 380 390
pF1KE1 SAPTPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH
:::.:::::::.: :::.:::::::.:::.::..... :
NP_004 SAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK
370 380 390
>>NP_004219 (OMIM: 602488) cytohesin-2 isoform 2 [Homo s (399 aa)
initn: 2300 init1: 2275 opt: 2275 Z-score: 1904.4 bits: 361.2 E(85289): 2.5e-99
Smith-Waterman score: 2275; 83.0% identity (94.4% similar) in 395 aa overlap (3-397:2-396)
10 20 30 40 50 60
pF1KE1 MEEDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEERKNM
:: : : ::: :::.:::::::::::::..::::..:..:. .:.:.: ..: :..
NP_004 MEDGVYEPPDLTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEANEGSKTL
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 QRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERD
:::...::::::::::::::::::.::.::.:: :.::.::::::::::::::::::::.
NP_004 QRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGERE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 EFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVF
:.:. ::::::.::::::::::::::::::::::::::::::::::::::::: :: :::
NP_004 ELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 QSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIK
::::::::::::.::::::::::::.::: .:::.:::::::.:::::::::::::.::.
NP_004 QSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLYDSIR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 NEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEP
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 RGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPT
::::::::::::::.: .::::::::::.:: :.::::::::::::::::: ::::::::
NP_004 RGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPT
300 310 320 330 340 350
370 380 390
pF1KE1 PEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH
:::.:::: :.::.: ::::::::::::..: :..
NP_004 QEEKDEWIKSIQAAVSVDPFYEMLAARKKRISVKKKQEQP
360 370 380 390
397 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:13:34 2016 done: Sun Nov 6 12:13:36 2016
Total Scan time: 8.420 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]