Result of FASTA (omim) for
pFN21AE1132
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1132, 308 aa
1>>>pF1KE1132 308 - 308 aa - 308 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6202+/-0.000295; mu= 14.6268+/- 0.019
mean_var=74.7757+/-14.805, 0's: 0 Z-trim(118.1): 127 B-trim: 256 in 1/56
Lambda= 0.148318
statistics sampled from 30603 (30731) to 30603 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.72), E-opt: 0.2 (0.36), width: 16
Scan time: 8.300
The best scores are: opt bits E(85289)
NP_071432 (OMIM: 609267) melanoma-associated antig ( 307) 2021 441.3 1.2e-123
NP_619649 (OMIM: 608243) non-structural maintenanc ( 304) 986 219.8 5.5e-57
NP_065983 (OMIM: 300759) melanoma-associated antig ( 957) 750 169.6 2.3e-41
NP_957516 (OMIM: 300470,300971) melanoma-associate ( 606) 728 164.8 4e-40
NP_055414 (OMIM: 300470,300971) melanoma-associate ( 606) 728 164.8 4e-40
NP_803182 (OMIM: 300470,300971) melanoma-associate ( 606) 728 164.8 4e-40
NP_001258113 (OMIM: 300132) trophinin isoform 7 [H (1034) 669 152.3 4e-36
NP_008917 (OMIM: 300224) melanoma-associated antig ( 778) 667 151.8 4.2e-36
NP_001005332 (OMIM: 300224) melanoma-associated an ( 778) 667 151.8 4.2e-36
XP_016885467 (OMIM: 300224) PREDICTED: melanoma-as ( 778) 667 151.8 4.2e-36
XP_011529137 (OMIM: 300224) PREDICTED: melanoma-as ( 778) 667 151.8 4.2e-36
XP_016885469 (OMIM: 300224) PREDICTED: melanoma-as ( 778) 667 151.8 4.2e-36
XP_016885468 (OMIM: 300224) PREDICTED: melanoma-as ( 778) 667 151.8 4.2e-36
NP_001005333 (OMIM: 300224) melanoma-associated an ( 834) 667 151.8 4.5e-36
XP_016885257 (OMIM: 300132) PREDICTED: trophinin i (1387) 669 152.3 5.1e-36
XP_011529116 (OMIM: 300132) PREDICTED: trophinin i (1387) 669 152.3 5.1e-36
XP_011529111 (OMIM: 300132) PREDICTED: trophinin i (1431) 669 152.3 5.2e-36
XP_011529115 (OMIM: 300132) PREDICTED: trophinin i (1431) 669 152.3 5.2e-36
XP_011529110 (OMIM: 300132) PREDICTED: trophinin i (1431) 669 152.3 5.2e-36
XP_011529114 (OMIM: 300132) PREDICTED: trophinin i (1431) 669 152.3 5.2e-36
XP_011529113 (OMIM: 300132) PREDICTED: trophinin i (1431) 669 152.3 5.2e-36
NP_001034794 (OMIM: 300132) trophinin isoform 5 [H (1431) 669 152.3 5.2e-36
XP_016885256 (OMIM: 300132) PREDICTED: trophinin i (1431) 669 152.3 5.2e-36
XP_006724663 (OMIM: 300132) PREDICTED: trophinin i (1431) 669 152.3 5.2e-36
NP_061939 (OMIM: 176270,605283,615547) MAGE-like p (1249) 656 149.5 3.2e-35
NP_808225 (OMIM: 300132) trophinin isoform 4 [Homo ( 309) 647 147.3 3.8e-35
XP_016885262 (OMIM: 300132) PREDICTED: trophinin i ( 662) 647 147.4 7.2e-35
XP_016885261 (OMIM: 300132) PREDICTED: trophinin i ( 662) 647 147.4 7.2e-35
XP_016885260 (OMIM: 300132) PREDICTED: trophinin i ( 706) 647 147.5 7.6e-35
NP_057241 (OMIM: 300132) trophinin isoform 2 [Homo ( 706) 647 147.5 7.6e-35
XP_016885259 (OMIM: 300132) PREDICTED: trophinin i ( 706) 647 147.5 7.6e-35
XP_016885258 (OMIM: 300132) PREDICTED: trophinin i ( 706) 647 147.5 7.6e-35
NP_808224 (OMIM: 300132) trophinin isoform 2 [Homo ( 706) 647 147.5 7.6e-35
NP_002358 (OMIM: 300153) melanoma-associated antig ( 346) 634 144.5 2.9e-34
NP_872312 (OMIM: 300761) melanoma-associated antig ( 347) 633 144.3 3.3e-34
XP_011543869 (OMIM: 300763) PREDICTED: melanoma-as ( 336) 626 142.8 9.2e-34
NP_001264236 (OMIM: 300763) melanoma-associated an ( 336) 626 142.8 9.2e-34
XP_011543755 (OMIM: 300762) PREDICTED: melanoma-as ( 324) 619 141.3 2.5e-33
XP_011543756 (OMIM: 300762) PREDICTED: melanoma-as ( 324) 619 141.3 2.5e-33
NP_001093391 (OMIM: 300762) melanoma-associated an ( 324) 619 141.3 2.5e-33
NP_002478 (OMIM: 176270,602117) necdin [Homo sapie ( 321) 606 138.5 1.7e-32
NP_803881 (OMIM: 300765) melanoma-associated antig ( 739) 610 139.6 1.9e-32
XP_011529124 (OMIM: 300765) PREDICTED: melanoma-as ( 739) 610 139.6 1.9e-32
NP_001092270 (OMIM: 300702) melanoma-associated an ( 739) 610 139.6 1.9e-32
XP_016885365 (OMIM: 300765) PREDICTED: melanoma-as ( 739) 610 139.6 1.9e-32
NP_110428 (OMIM: 300765) melanoma-associated antig ( 741) 610 139.6 1.9e-32
NP_001258992 (OMIM: 300702) melanoma-associated an ( 741) 610 139.6 1.9e-32
NP_001258991 (OMIM: 300702) melanoma-associated an ( 741) 610 139.6 1.9e-32
NP_803879 (OMIM: 300765) melanoma-associated antig ( 741) 610 139.6 1.9e-32
XP_006724671 (OMIM: 300765) PREDICTED: melanoma-as ( 741) 610 139.6 1.9e-32
>>NP_071432 (OMIM: 609267) melanoma-associated antigen F (307 aa)
initn: 1052 init1: 1052 opt: 2021 Z-score: 2341.0 bits: 441.3 E(85289): 1.2e-123
Smith-Waterman score: 2021; 99.4% identity (99.4% similar) in 308 aa overlap (1-308:1-307)
10 20 30 40 50 60
pF1KE1 MLQTPESRGLPVPQAEGEKDGGHDGETRAPTASQERPKEELGAGREEGAAEPALTRKGAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MLQTPESRGLPVPQAEGEKDGGHDGETRAPTASQERPKEELGAGREEGAAEPALTRKGAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ALAAKALARRRAYRRLNRTVAELVQFLLVKDKKKSPITRSEMVKYVIGDLKILFPDIIAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 ALAAKALARRRAYRRLNRTVAELVQFLLVKDKKKSPITRSEMVKYVIGDLKILFPDIIAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AAEHLRYVFGFELKQFDRKHHTYILINKLKPLEEEEEEEDLGGDGPRLGLLMMILGLIYM
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
NP_071 AAEHLRYVFGFELKQFDRKHHTYILINKLKPLEEEEEE-DLGGDGPRLGLLMMILGLIYM
130 140 150 160 170
190 200 210 220 230 240
pF1KE1 RGNSAREAQVWEMLRRLGVQPSKYHFLFGYPKRLIMEDFVQQRYLSYRRVPHTNPPAYEF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
NP_071 RGNSAREAQVWEMLRRLGVQPSKYHFLFGYPKRLIMEDFVQQRYLSYRRVPHTNPPEYEF
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 SWGPRSNLEISKMEVLGFVAKLHKKEPQHWPVQYREALADEADRARAKARAEASMRARAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 SWGPRSNLEISKMEVLGFVAKLHKKEPQHWPVQYREALADEADRARAKARAEASMRARAS
240 250 260 270 280 290
pF1KE1 ARAGIHLW
::::::::
NP_071 ARAGIHLW
300
>>NP_619649 (OMIM: 608243) non-structural maintenance of (304 aa)
initn: 984 init1: 595 opt: 986 Z-score: 1144.1 bits: 219.8 E(85289): 5.5e-57
Smith-Waterman score: 986; 51.0% identity (75.2% similar) in 306 aa overlap (1-293:1-301)
10 20 30 40
pF1KE1 MLQTPESRGLPVPQAEGEKDGGHDGETRAPTA-----------SQERPKEELGAGREEGA
::: :..:: ::: ..: .:.:. : : ..: :. : : .:.
NP_619 MLQKPRNRGRSGGQAERDRDWSHSGNPGASRAGEDARVLRDGFAEEAPSTSRGPGGSQGS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 AEPALTRKGAR-ALAAKALARRRAYRRLNRTVAELVQFLLVKDKKKSPITRSEMVKYVIG
: . .::: : :: :.. : . ..:. :.:::::::.::.:: :: :....:.:::
NP_619 QGP--SPQGARRAQAAPAVGPR-SQKQLELKVSELVQFLLIKDQKKIPIKRADILKHVIG
70 80 90 100 110
110 120 130 140 150 160
pF1KE1 DLKILFPDIIARAAEHLRYVFGFELKQFDRKHHTYILINKLKPLEEEEEEEDLGGDG-PR
: : .:::.. ::::.:.::::..: ... : .:::::: :.:.::. : . : .: :
NP_619 DYKDIFPDLFKRAAERLQYVFGYKLVELEPKSNTYILINTLEPVEEDAEMR--GDQGTPT
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 LGLLMMILGLIYMRGNSAREAQVWEMLRRLGVQPSKYHFLFGYPKRLIMEDFVQQRYLSY
::::..::::.:.::. .:...:..:::::: :.: :..:: ::.:: ::::.:::: :
NP_619 TGLLMIVLGLIFMKGNTIKETEAWDFLRRLGVYPTKKHLIFGDPKKLITEDFVRQRYLEY
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 RRVPHTNPPAYEFSWGPRSNLEISKMEVLGFVAKLHKKEPQHWPVQYREALADEADRARA
::.:::.: :::.::::.::: :::.:: ::::.:...:. ::.:: :::::: .:::
NP_619 RRIPHTDPVDYEFQWGPRTNLETSKMKVLKFVAKVHNQDPKDWPAQYCEALADEENRARP
240 250 260 270 280 290
290 300
pF1KE1 KARAEASMRARASARAGIHLW
. . :
NP_619 QPSGPAPSS
300
>>NP_065983 (OMIM: 300759) melanoma-associated antigen E (957 aa)
initn: 750 init1: 484 opt: 750 Z-score: 863.8 bits: 169.6 E(85289): 2.3e-41
Smith-Waterman score: 750; 52.1% identity (77.5% similar) in 213 aa overlap (76-288:491-701)
50 60 70 80 90 100
pF1KE1 EEGAAEPALTRKGARALAAKALARRRAYRRLNRTVAELVQFLLVKDKKKSPITRSEMVKY
....::::.:::::::..: :: .::: .:
NP_065 VLRDCESPNSISIMGLNTSRVAITLKPQDPMEQNVAELLQFLLVKDQSKYPIRESEMREY
470 480 490 500 510 520
110 120 130 140 150 160
pF1KE1 VIGDLKILFPDIIARAAEHLRYVFGFELKQFDRKHHTYILINKLKPLEEEEEEEDLGGDG
.. . . ::.:. ::: ::. .: :::...: . :::::.::: :. : ::. .:
NP_065 IVKEYRNQFPEILRRAAAHLECIFRFELRELDPEAHTYILLNKLGPVPFEGLEES--PNG
530 540 550 560 570
170 180 190 200 210 220
pF1KE1 PRLGLLMMILGLIYMRGNSAREAQVWEMLRRLGVQPSKYHFLFGYPKRLIMEDFVQQRYL
:..:::::::: :.. ::.:.::..:::: :.::: . .:: ::::. .:: ::::
NP_065 PKMGLLMMILGQIFLNGNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYL
580 590 600 610 620 630
230 240 250 260 270 280
pF1KE1 SYRRVPHTNPPAYEFSWGPRSNLEISKMEVLGFVAKLHKKEPQHWPVQYREALADEADRA
.:: : .: ::: :::::.:: .::..: :.::...:.:. :: .: ::: ..: ::
NP_065 DYRPVTDCKPVEYEFFWGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYNEALEEDAARA
640 650 660 670 680 690
290 300
pF1KE1 RAKARAEASMRARASARAGIHLW
:.
NP_065 FAEGWQALPHFRRPFFEEAAAEVPSPDSEVSSYSSKYAPHSWPESRLESKARKLVQLFLL
700 710 720 730 740 750
>--
initn: 598 init1: 296 opt: 585 Z-score: 672.9 bits: 134.3 E(85289): 9.6e-31
Smith-Waterman score: 585; 40.0% identity (66.9% similar) in 245 aa overlap (46-290:715-949)
20 30 40 50 60 70
pF1KE1 EGEKDGGHDGETRAPTASQERPKEELGAGREEGAAEPALTRKGARALAAKALARRRAYRR
::.::: . . . ..: . :
NP_065 EKYNEALEEDAARAFAEGWQALPHFRRPFFEEAAAEVPSPDSEVSSYSSKYAPHSWPESR
690 700 710 720 730 740
80 90 100 110 120 130
pF1KE1 LNRTVAELVQFLLVKDKKKSPITRSEMVKYVIGDLKILFPDIIARAAEHLRYVFGFELKQ
:. . .:::..:. :. : :: .. .. :. . . .:::.. :::. : .:.: ::
NP_065 LESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVYGTELVV
750 760 770 780 790 800
140 150 160 170 180 190
pF1KE1 FDRKHHTYILINKLKPLEEEEEEEDLGGDGPRLGLLMMILGLIYMRGNSAREAQVWEMLR
.: ..:.: : :. . .:: :: : . . : ..::..:..:.. :: :::. :: .::
NP_065 LDPRNHSYTLYNR-REMEETEEIVD-SPNRPGNNFLMQVLSFIFIMGNHARESAVWAFLR
810 820 830 840 850 860
200 210 220 230 240 250
pF1KE1 RLGVQPSKYHFLFGYPKRLIMEDFVQQRYLSYRRVPHTNPPAYEFSWGPRSNLEISKMEV
:::: .. : .: ...:::.. ::: ..: ::: ::::. :: :::..
NP_065 GLGVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETSKMKA
870 880 890 900 910
260 270 280 290 300
pF1KE1 LGFVAKLHKKEPQHWPVQYREALADEADRARAKARAEASMRARASARAGIHLW
: .::..:.:::: :: :::::. :::.:: . :
NP_065 LRYVARIHRKEPQDWPQQYREAMEDEANRADVGHRQIFVHNFR
920 930 940 950
>>NP_957516 (OMIM: 300470,300971) melanoma-associated an (606 aa)
initn: 751 init1: 451 opt: 728 Z-score: 841.3 bits: 164.8 E(85289): 4e-40
Smith-Waterman score: 731; 41.6% identity (66.2% similar) in 334 aa overlap (12-307:180-507)
10 20 30 40
pF1KE1 MLQTPESRGLPVPQAEGEKDGGHDGETRAPTASQERPKEEL
: . .::.::. : . :.. .: .. :
NP_957 ADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKAL
150 160 170 180 190 200
50 60 70
pF1KE1 GAGREEGAAEPALT---RKGAR----ALAAKAL------------ARRRAYRRLN-----
:. . :.. .. :...: : : .:: ::::: . .
NP_957 MASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPE
210 220 230 240 250 260
80 90 100 110 120
pF1KE1 ----RTVA-------ELVQFLLVKDKKKSPITRSEMVKYVIGDLKILFPDIIARAAEHLR
: :: .::..::.::. : :: ::.:.: .: . ..:.:: ::. :.
NP_957 APPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLE
270 280 290 300 310 320
130 140 150 160 170 180
pF1KE1 YVFGFELKQFDRKHHTYILINKLKPLEEEEEEEDLGG--DGPRLGLLMMILGLIYMRGNS
:::..::..:.. : :::.. :.: . :: :.:.:::::..:..:.: ::
NP_957 KVFGIQLKEIDKNDHLYILLSTLEPTDAG----ILGTTKDSPKLGLLMVLLSIIFMNGNR
330 340 350 360 370 380
190 200 210 220 230 240
pF1KE1 AREAQVWEMLRRLGVQPSKYHFLFGYPKRLIMEDFVQQRYLSYRRVPHTNPPAYEFSWGP
. :: .::.::.::..:. .: ::: :.:: ..::.:.::.: :::..::: ::: ::
NP_957 SSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGL
390 400 410 420 430 440
250 260 270 280 290 300
pF1KE1 RSNLEISKMEVLGFVAKLHKKEPQHWPVQYREALADEAD-RARAKARAEASMRARASARA
:: : :::.:: :. :..::.:..: .:::::. ::: .: :.: :::. ::. ::
NP_957 RSYYETSKMKVLKFACKVQKKDPKEWAAQYREAM--EADLKAAAEAAAEAKARAEIRARM
450 460 470 480 490 500
pF1KE1 GIHLW
:: :
NP_957 GIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAKAQESGSASTGASTSTNNSASASA
510 520 530 540 550 560
>>NP_055414 (OMIM: 300470,300971) melanoma-associated an (606 aa)
initn: 751 init1: 451 opt: 728 Z-score: 841.3 bits: 164.8 E(85289): 4e-40
Smith-Waterman score: 731; 41.6% identity (66.2% similar) in 334 aa overlap (12-307:180-507)
10 20 30 40
pF1KE1 MLQTPESRGLPVPQAEGEKDGGHDGETRAPTASQERPKEEL
: . .::.::. : . :.. .: .. :
NP_055 ADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKAL
150 160 170 180 190 200
50 60 70
pF1KE1 GAGREEGAAEPALT---RKGAR----ALAAKAL------------ARRRAYRRLN-----
:. . :.. .. :...: : : .:: ::::: . .
NP_055 MASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPE
210 220 230 240 250 260
80 90 100 110 120
pF1KE1 ----RTVA-------ELVQFLLVKDKKKSPITRSEMVKYVIGDLKILFPDIIARAAEHLR
: :: .::..::.::. : :: ::.:.: .: . ..:.:: ::. :.
NP_055 APPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLE
270 280 290 300 310 320
130 140 150 160 170 180
pF1KE1 YVFGFELKQFDRKHHTYILINKLKPLEEEEEEEDLGG--DGPRLGLLMMILGLIYMRGNS
:::..::..:.. : :::.. :.: . :: :.:.:::::..:..:.: ::
NP_055 KVFGIQLKEIDKNDHLYILLSTLEPTDAG----ILGTTKDSPKLGLLMVLLSIIFMNGNR
330 340 350 360 370 380
190 200 210 220 230 240
pF1KE1 AREAQVWEMLRRLGVQPSKYHFLFGYPKRLIMEDFVQQRYLSYRRVPHTNPPAYEFSWGP
. :: .::.::.::..:. .: ::: :.:: ..::.:.::.: :::..::: ::: ::
NP_055 SSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGL
390 400 410 420 430 440
250 260 270 280 290 300
pF1KE1 RSNLEISKMEVLGFVAKLHKKEPQHWPVQYREALADEAD-RARAKARAEASMRARASARA
:: : :::.:: :. :..::.:..: .:::::. ::: .: :.: :::. ::. ::
NP_055 RSYYETSKMKVLKFACKVQKKDPKEWAAQYREAM--EADLKAAAEAAAEAKARAEIRARM
450 460 470 480 490 500
pF1KE1 GIHLW
:: :
NP_055 GIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAKAQESGSASTGASTSTNNSASASA
510 520 530 540 550 560
>>NP_803182 (OMIM: 300470,300971) melanoma-associated an (606 aa)
initn: 751 init1: 451 opt: 728 Z-score: 841.3 bits: 164.8 E(85289): 4e-40
Smith-Waterman score: 731; 41.6% identity (66.2% similar) in 334 aa overlap (12-307:180-507)
10 20 30 40
pF1KE1 MLQTPESRGLPVPQAEGEKDGGHDGETRAPTASQERPKEEL
: . .::.::. : . :.. .: .. :
NP_803 ADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKAL
150 160 170 180 190 200
50 60 70
pF1KE1 GAGREEGAAEPALT---RKGAR----ALAAKAL------------ARRRAYRRLN-----
:. . :.. .. :...: : : .:: ::::: . .
NP_803 MASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPE
210 220 230 240 250 260
80 90 100 110 120
pF1KE1 ----RTVA-------ELVQFLLVKDKKKSPITRSEMVKYVIGDLKILFPDIIARAAEHLR
: :: .::..::.::. : :: ::.:.: .: . ..:.:: ::. :.
NP_803 APPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLE
270 280 290 300 310 320
130 140 150 160 170 180
pF1KE1 YVFGFELKQFDRKHHTYILINKLKPLEEEEEEEDLGG--DGPRLGLLMMILGLIYMRGNS
:::..::..:.. : :::.. :.: . :: :.:.:::::..:..:.: ::
NP_803 KVFGIQLKEIDKNDHLYILLSTLEPTDAG----ILGTTKDSPKLGLLMVLLSIIFMNGNR
330 340 350 360 370 380
190 200 210 220 230 240
pF1KE1 AREAQVWEMLRRLGVQPSKYHFLFGYPKRLIMEDFVQQRYLSYRRVPHTNPPAYEFSWGP
. :: .::.::.::..:. .: ::: :.:: ..::.:.::.: :::..::: ::: ::
NP_803 SSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGL
390 400 410 420 430 440
250 260 270 280 290 300
pF1KE1 RSNLEISKMEVLGFVAKLHKKEPQHWPVQYREALADEAD-RARAKARAEASMRARASARA
:: : :::.:: :. :..::.:..: .:::::. ::: .: :.: :::. ::. ::
NP_803 RSYYETSKMKVLKFACKVQKKDPKEWAAQYREAM--EADLKAAAEAAAEAKARAEIRARM
450 460 470 480 490 500
pF1KE1 GIHLW
:: :
NP_803 GIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAKAQESGSASTGASTSTNNSASASA
510 520 530 540 550 560
>>NP_001258113 (OMIM: 300132) trophinin isoform 7 [Homo (1034 aa)
initn: 671 init1: 446 opt: 669 Z-score: 769.6 bits: 152.3 E(85289): 4e-36
Smith-Waterman score: 669; 47.8% identity (71.6% similar) in 232 aa overlap (76-305:47-272)
50 60 70 80 90 100
pF1KE1 EEGAAEPALTRKGARALAAKALARRRAYRRLNRTVAELVQFLLVKDKKKSPITRSEMVKY
:.. . .::..:::::. : :: ::.:..
NP_001 KHLNGDERSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRD
20 30 40 50 60 70
110 120 130 140 150 160
pF1KE1 VIGDLKILFPDIIARAAEHLRYVFGFELKQFDRKHHTYILINKLKPLEEEEEEEDLGG--
:: . ::.:: ::. :. .: .::..:.. ::::. .: ::
NP_001 VIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQSSLYILIST-----QESSAGILGTTK
80 90 100 110 120 130
170 180 190 200 210 220
pF1KE1 DGPRLGLLMMILGLIYMRGNSAREAQVWEMLRRLGVQPSKYHFLFGYPKRLIMEDFVQQR
: :.:::::.::..:.: ::.: :: .::.::.::..:. : ::: ..:: ..::.:.
NP_001 DTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQK
140 150 160 170 180 190
230 240 250 260 270 280
pF1KE1 YLSYRRVPHTNPPAYEFSWGPRSNLEISKMEVLGFVAKLHKKEPQHWPVQYREALADEAD
:: :.:::.. :: ::: :: :: : :::.:: :. ...::.:. : ::::::. :.
NP_001 YLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEV-
200 210 220 230 240 250
290 300
pF1KE1 RARAKARAEASMRARASARAGIHLW
.: : : ::: ::.: :. ::
NP_001 QAAAVAVAEAEARAEARAQMGIGEEAVAGPWNWDDMDIDCLTREELGDDAQAWSRFSFEI
260 270 280 290 300 310
>>NP_008917 (OMIM: 300224) melanoma-associated antigen D (778 aa)
initn: 711 init1: 441 opt: 667 Z-score: 769.1 bits: 151.8 E(85289): 4.2e-36
Smith-Waterman score: 667; 45.4% identity (69.5% similar) in 249 aa overlap (59-305:454-696)
30 40 50 60 70 80
pF1KE1 APTASQERPKEELGAGREEGAAEPALTRKGARALAAKALARRRAYRRLNRTVAELVQFLL
.:: . :. : :.. . .::..:.
NP_008 LPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLM
430 440 450 460 470 480
90 100 110 120 130 140
pF1KE1 VKDKKKSPITRSEMVKYVIGDLKILFPDIIARAAEHLRYVFGFELKQFDRKHHTYILINK
.:: : :: ::::.. .: . ..:.:: :: :. ::..::..:...: ::::.
NP_008 LKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILIST
490 500 510 520 530 540
150 160 170 180 190 200
pF1KE1 LKPLEEEEEEEDLGG--DGPRLGLLMMILGLIYMRGNSAREAQVWEMLRRLGVQPSKYHF
: : :: : :.::::..:::.:.: :: : :: .:: ::..:..:. :
NP_008 --P---ESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHP
550 560 570 580 590
210 220 230 240 250 260
pF1KE1 LFGYPKRLIMEDFVQQRYLSYRRVPHTNPPAYEFSWGPRSNLEISKMEVLGFVAKLHKKE
:.: ..:. .::.:.::.:::::..::: ::: :: :: : :::.:: :.:...:..
NP_008 LLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRD
600 610 620 630 640 650
270 280 290 300
pF1KE1 PQHWPVQYREALADEADRARAKARAEASMRARASARAGIHLW
:. : .:. :: :::: : : ::: ::.: .: ::
NP_008 PRDWTAQFMEA-ADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTW
660 670 680 690 700 710
NP_008 DEEGDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWV
720 730 740 750 760 770
>>NP_001005332 (OMIM: 300224) melanoma-associated antige (778 aa)
initn: 711 init1: 441 opt: 667 Z-score: 769.1 bits: 151.8 E(85289): 4.2e-36
Smith-Waterman score: 667; 45.4% identity (69.5% similar) in 249 aa overlap (59-305:454-696)
30 40 50 60 70 80
pF1KE1 APTASQERPKEELGAGREEGAAEPALTRKGARALAAKALARRRAYRRLNRTVAELVQFLL
.:: . :. : :.. . .::..:.
NP_001 LPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLM
430 440 450 460 470 480
90 100 110 120 130 140
pF1KE1 VKDKKKSPITRSEMVKYVIGDLKILFPDIIARAAEHLRYVFGFELKQFDRKHHTYILINK
.:: : :: ::::.. .: . ..:.:: :: :. ::..::..:...: ::::.
NP_001 LKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILIST
490 500 510 520 530 540
150 160 170 180 190 200
pF1KE1 LKPLEEEEEEEDLGG--DGPRLGLLMMILGLIYMRGNSAREAQVWEMLRRLGVQPSKYHF
: : :: : :.::::..:::.:.: :: : :: .:: ::..:..:. :
NP_001 --P---ESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHP
550 560 570 580 590
210 220 230 240 250 260
pF1KE1 LFGYPKRLIMEDFVQQRYLSYRRVPHTNPPAYEFSWGPRSNLEISKMEVLGFVAKLHKKE
:.: ..:. .::.:.::.:::::..::: ::: :: :: : :::.:: :.:...:..
NP_001 LLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRD
600 610 620 630 640 650
270 280 290 300
pF1KE1 PQHWPVQYREALADEADRARAKARAEASMRARASARAGIHLW
:. : .:. :: :::: : : ::: ::.: .: ::
NP_001 PRDWTAQFMEA-ADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTW
660 670 680 690 700 710
NP_001 DEEGDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWV
720 730 740 750 760 770
>>XP_016885467 (OMIM: 300224) PREDICTED: melanoma-associ (778 aa)
initn: 711 init1: 441 opt: 667 Z-score: 769.1 bits: 151.8 E(85289): 4.2e-36
Smith-Waterman score: 667; 45.4% identity (69.5% similar) in 249 aa overlap (59-305:454-696)
30 40 50 60 70 80
pF1KE1 APTASQERPKEELGAGREEGAAEPALTRKGARALAAKALARRRAYRRLNRTVAELVQFLL
.:: . :. : :.. . .::..:.
XP_016 LPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLM
430 440 450 460 470 480
90 100 110 120 130 140
pF1KE1 VKDKKKSPITRSEMVKYVIGDLKILFPDIIARAAEHLRYVFGFELKQFDRKHHTYILINK
.:: : :: ::::.. .: . ..:.:: :: :. ::..::..:...: ::::.
XP_016 LKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILIST
490 500 510 520 530 540
150 160 170 180 190 200
pF1KE1 LKPLEEEEEEEDLGG--DGPRLGLLMMILGLIYMRGNSAREAQVWEMLRRLGVQPSKYHF
: : :: : :.::::..:::.:.: :: : :: .:: ::..:..:. :
XP_016 --P---ESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHP
550 560 570 580 590
210 220 230 240 250 260
pF1KE1 LFGYPKRLIMEDFVQQRYLSYRRVPHTNPPAYEFSWGPRSNLEISKMEVLGFVAKLHKKE
:.: ..:. .::.:.::.:::::..::: ::: :: :: : :::.:: :.:...:..
XP_016 LLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRD
600 610 620 630 640 650
270 280 290 300
pF1KE1 PQHWPVQYREALADEADRARAKARAEASMRARASARAGIHLW
:. : .:. :: :::: : : ::: ::.: .: ::
XP_016 PRDWTAQFMEA-ADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTW
660 670 680 690 700 710
XP_016 DEEGDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWV
720 730 740 750 760 770
308 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:06:34 2016 done: Sun Nov 6 22:06:36 2016
Total Scan time: 8.300 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]