Result of FASTA (omim) for
pFN21AE1126
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1126, 631 aa
1>>>pF1KE1126 631 - 631 aa - 631 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0188+/-0.000366; mu= 18.5416+/- 0.023
mean_var=171.0828+/-35.814, 0's: 0 Z-trim(119.2): 144 B-trim: 0 in 0/51
Lambda= 0.098055
statistics sampled from 32679 (32878) to 32679 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.385), width: 16
Scan time: 10.830
The best scores are: opt bits E(85289)
NP_009079 (OMIM: 601237) RING finger protein 112 [ ( 631) 4315 623.1 9e-178
XP_006721634 (OMIM: 601237) PREDICTED: RING finger ( 639) 4289 619.4 1.2e-176
XP_006721635 (OMIM: 601237) PREDICTED: RING finger ( 638) 4271 616.9 6.8e-176
XP_006721636 (OMIM: 601237) PREDICTED: RING finger ( 615) 4122 595.8 1.5e-169
NP_001121185 (OMIM: 182600,606439,613708) atlastin ( 553) 324 58.5 7.5e-08
NP_853629 (OMIM: 182600,606439,613708) atlastin-1 ( 553) 324 58.5 7.5e-08
NP_056999 (OMIM: 182600,606439,613708) atlastin-1 ( 558) 324 58.5 7.6e-08
NP_001276977 (OMIM: 609369,615632) atlastin-3 isof ( 523) 293 54.0 1.5e-06
NP_056274 (OMIM: 609369,615632) atlastin-3 isoform ( 541) 293 54.1 1.6e-06
NP_071769 (OMIM: 609368) atlastin-2 isoform 1 [Hom ( 579) 288 53.4 2.6e-06
NP_001317391 (OMIM: 609368) atlastin-2 isoform 7 [ ( 579) 288 53.4 2.6e-06
NP_001129145 (OMIM: 609368) atlastin-2 isoform 2 [ ( 583) 288 53.4 2.7e-06
NP_001317392 (OMIM: 609368) atlastin-2 isoform 8 [ ( 584) 288 53.4 2.7e-06
XP_016860176 (OMIM: 609368) PREDICTED: atlastin-2 ( 530) 284 52.8 3.7e-06
XP_011531322 (OMIM: 609368) PREDICTED: atlastin-2 ( 530) 284 52.8 3.7e-06
XP_016860175 (OMIM: 609368) PREDICTED: atlastin-2 ( 530) 284 52.8 3.7e-06
NP_001295005 (OMIM: 609368) atlastin-2 isoform 3 [ ( 565) 284 52.8 3.9e-06
NP_001317388 (OMIM: 609368) atlastin-2 isoform 5 [ ( 566) 284 52.8 3.9e-06
XP_006718556 (OMIM: 609369,615632) PREDICTED: atla ( 522) 248 47.7 0.00013
XP_011542587 (OMIM: 607868) PREDICTED: E3 ubiquiti ( 391) 229 44.8 0.00068
XP_016857901 (OMIM: 607868) PREDICTED: E3 ubiquiti ( 467) 229 44.9 0.00076
NP_660215 (OMIM: 607868) E3 ubiquitin-protein liga ( 468) 229 44.9 0.00076
>>NP_009079 (OMIM: 601237) RING finger protein 112 [Homo (631 aa)
initn: 4315 init1: 4315 opt: 4315 Z-score: 3312.6 bits: 623.1 E(85289): 9e-178
Smith-Waterman score: 4315; 100.0% identity (100.0% similar) in 631 aa overlap (1-631:1-631)
10 20 30 40 50 60
pF1KE1 MPRPALSVTSFCHRLGKRERKQSFMGNSGNSWSHTPFPKLELGLGPQPMAPRELPTCSIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MPRPALSVTSFCHRLGKRERKQSFMGNSGNSWSHTPFPKLELGLGPQPMAPRELPTCSIC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LERLRDPISLDCGHDFCIRCFSTHRLPGCEPPCCPECRKICKQKRGLRSLGEKMKLLPQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LERLRDPISLDCGHDFCIRCFSTHRLPGCEPPCCPECRKICKQKRGLRSLGEKMKLLPQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 PLPPALQETCPVRAEPLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 PLPPALQETCPVRAEPLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GKSFLLNHLLQGLPGLESGEGGRPRGGEASLQGCRWGANGLARGIWMWSHPFLLGKEGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GKSFLLNHLLQGLPGLESGEGGRPRGGEASLQGCRWGANGLARGIWMWSHPFLLGKEGKK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VAVFLVDTGDAMSPELSRETRIKLCALTTMLSSYQILSTSQELKDTDLDYLEMFVHVAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VAVFLVDTGDAMSPELSRETRIKLCALTTMLSSYQILSTSQELKDTDLDYLEMFVHVAEV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 MGKHYGMVPIQHLDLLVRDSSHPNKAGQGHVGNIFQRLSGRYPKVQELLQGKRARCCLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MGKHYGMVPIQHLDLLVRDSSHPNKAGQGHVGNIFQRLSGRYPKVQELLQGKRARCCLLP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 APGRRRMNQGHASPGDTDDDFRHLLGAYVSDVLSAAPQHAKSRCQGYWNEGRAVARGDRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 APGRRRMNQGHASPGDTDDDFRHLLGAYVSDVLSAAPQHAKSRCQGYWNEGRAVARGDRR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 LLTGQQLAQEIKNLSGWMGRTGPGFTSPDEMAAQLHDLRKVEAAKREFEEYVRQQDVATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LLTGQQLAQEIKNLSGWMGRTGPGFTSPDEMAAQLHDLRKVEAAKREFEEYVRQQDVATK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 RIFSALRVLPDTMRNLLSTQKDAILARHGVALLCKGRDQTLEALEAELQATAKAFMDSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RIFSALRVLPDTMRNLLSTQKDAILARHGVALLCKGRDQTLEALEAELQATAKAFMDSYT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 MRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAAEAGMVAAGAAVGATGAAVVGGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAAEAGMVAAGAAVGATGAAVVGGGV
550 560 570 580 590 600
610 620 630
pF1KE1 GAGLAATVGCMEKEEDERLLEGDREPLLQEE
:::::::::::::::::::::::::::::::
NP_009 GAGLAATVGCMEKEEDERLLEGDREPLLQEE
610 620 630
>>XP_006721634 (OMIM: 601237) PREDICTED: RING finger pro (639 aa)
initn: 2461 init1: 2369 opt: 4289 Z-score: 3292.6 bits: 619.4 E(85289): 1.2e-176
Smith-Waterman score: 4289; 98.7% identity (98.7% similar) in 639 aa overlap (1-631:1-639)
10 20 30 40 50 60
pF1KE1 MPRPALSVTSFCHRLGKRERKQSFMGNSGNSWSHTPFPKLELGLGPQPMAPRELPTCSIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPRPALSVTSFCHRLGKRERKQSFMGNSGNSWSHTPFPKLELGLGPQPMAPRELPTCSIC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LERLRDPISLDCGHDFCIRCFSTHRLPGCEPPCCPECRKICKQKRGLRSLGEKMKLLPQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LERLRDPISLDCGHDFCIRCFSTHRLPGCEPPCCPECRKICKQKRGLRSLGEKMKLLPQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 PLPPALQETCPVRAEPLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLPPALQETCPVRAEPLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GKSFLLNHLLQGLPGLESGEGGRPRGGEASLQGCRWGANGLARGIWMWSHPFLLGKEGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKSFLLNHLLQGLPGLESGEGGRPRGGEASLQGCRWGANGLARGIWMWSHPFLLGKEGKK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VAVFLVDTGDAMSPELSRETRIKLCALTTMLSSYQILSTSQELKDTDLDYLEMFVHVAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VAVFLVDTGDAMSPELSRETRIKLCALTTMLSSYQILSTSQELKDTDLDYLEMFVHVAEV
250 260 270 280 290 300
310 320 330 340 350
pF1KE1 MGKHYGMVPIQHLDLLVRDSSHPNKAGQGHVGNIFQ--------RLSGRYPKVQELLQGK
:::::::::::::::::::::::::::::::::::: ::::::::::::::::
XP_006 MGKHYGMVPIQHLDLLVRDSSHPNKAGQGHVGNIFQSTPLAASQRLSGRYPKVQELLQGK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE1 RARCCLLPAPGRRRMNQGHASPGDTDDDFRHLLGAYVSDVLSAAPQHAKSRCQGYWNEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RARCCLLPAPGRRRMNQGHASPGDTDDDFRHLLGAYVSDVLSAAPQHAKSRCQGYWNEGR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE1 AVARGDRRLLTGQQLAQEIKNLSGWMGRTGPGFTSPDEMAAQLHDLRKVEAAKREFEEYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVARGDRRLLTGQQLAQEIKNLSGWMGRTGPGFTSPDEMAAQLHDLRKVEAAKREFEEYV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE1 RQQDVATKRIFSALRVLPDTMRNLLSTQKDAILARHGVALLCKGRDQTLEALEAELQATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQQDVATKRIFSALRVLPDTMRNLLSTQKDAILARHGVALLCKGRDQTLEALEAELQATA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE1 KAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAAEAGMVAAGAAVGATG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAAEAGMVAAGAAVGATG
550 560 570 580 590 600
600 610 620 630
pF1KE1 AAVVGGGVGAGLAATVGCMEKEEDERLLEGDREPLLQEE
:::::::::::::::::::::::::::::::::::::::
XP_006 AAVVGGGVGAGLAATVGCMEKEEDERLLEGDREPLLQEE
610 620 630
>>XP_006721635 (OMIM: 601237) PREDICTED: RING finger pro (638 aa)
initn: 2891 init1: 1953 opt: 4271 Z-score: 3278.9 bits: 616.9 E(85289): 6.8e-176
Smith-Waterman score: 4271; 98.6% identity (98.6% similar) in 639 aa overlap (1-631:1-638)
10 20 30 40 50 60
pF1KE1 MPRPALSVTSFCHRLGKRERKQSFMGNSGNSWSHTPFPKLELGLGPQPMAPRELPTCSIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPRPALSVTSFCHRLGKRERKQSFMGNSGNSWSHTPFPKLELGLGPQPMAPRELPTCSIC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LERLRDPISLDCGHDFCIRCFSTHRLPGCEPPCCPECRKICKQKRGLRSLGEKMKLLPQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LERLRDPISLDCGHDFCIRCFSTHRLPGCEPPCCPECRKICKQKRGLRSLGEKMKLLPQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 PLPPALQETCPVRAEPLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHS
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLPPALQ-TCPVRAEPLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHS
130 140 150 160 170
190 200 210 220 230 240
pF1KE1 GKSFLLNHLLQGLPGLESGEGGRPRGGEASLQGCRWGANGLARGIWMWSHPFLLGKEGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKSFLLNHLLQGLPGLESGEGGRPRGGEASLQGCRWGANGLARGIWMWSHPFLLGKEGKK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 VAVFLVDTGDAMSPELSRETRIKLCALTTMLSSYQILSTSQELKDTDLDYLEMFVHVAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VAVFLVDTGDAMSPELSRETRIKLCALTTMLSSYQILSTSQELKDTDLDYLEMFVHVAEV
240 250 260 270 280 290
310 320 330 340 350
pF1KE1 MGKHYGMVPIQHLDLLVRDSSHPNKAGQGHVGNIFQ--------RLSGRYPKVQELLQGK
:::::::::::::::::::::::::::::::::::: ::::::::::::::::
XP_006 MGKHYGMVPIQHLDLLVRDSSHPNKAGQGHVGNIFQSTPLAASQRLSGRYPKVQELLQGK
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 RARCCLLPAPGRRRMNQGHASPGDTDDDFRHLLGAYVSDVLSAAPQHAKSRCQGYWNEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RARCCLLPAPGRRRMNQGHASPGDTDDDFRHLLGAYVSDVLSAAPQHAKSRCQGYWNEGR
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE1 AVARGDRRLLTGQQLAQEIKNLSGWMGRTGPGFTSPDEMAAQLHDLRKVEAAKREFEEYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVARGDRRLLTGQQLAQEIKNLSGWMGRTGPGFTSPDEMAAQLHDLRKVEAAKREFEEYV
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE1 RQQDVATKRIFSALRVLPDTMRNLLSTQKDAILARHGVALLCKGRDQTLEALEAELQATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQQDVATKRIFSALRVLPDTMRNLLSTQKDAILARHGVALLCKGRDQTLEALEAELQATA
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE1 KAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAAEAGMVAAGAAVGATG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAAEAGMVAAGAAVGATG
540 550 560 570 580 590
600 610 620 630
pF1KE1 AAVVGGGVGAGLAATVGCMEKEEDERLLEGDREPLLQEE
:::::::::::::::::::::::::::::::::::::::
XP_006 AAVVGGGVGAGLAATVGCMEKEEDERLLEGDREPLLQEE
600 610 620 630
>>XP_006721636 (OMIM: 601237) PREDICTED: RING finger pro (615 aa)
initn: 2294 init1: 2202 opt: 4122 Z-score: 3165.1 bits: 595.8 E(85289): 1.5e-169
Smith-Waterman score: 4122; 98.7% identity (98.7% similar) in 615 aa overlap (25-631:1-615)
10 20 30 40 50 60
pF1KE1 MPRPALSVTSFCHRLGKRERKQSFMGNSGNSWSHTPFPKLELGLGPQPMAPRELPTCSIC
::::::::::::::::::::::::::::::::::::
XP_006 MGNSGNSWSHTPFPKLELGLGPQPMAPRELPTCSIC
10 20 30
70 80 90 100 110 120
pF1KE1 LERLRDPISLDCGHDFCIRCFSTHRLPGCEPPCCPECRKICKQKRGLRSLGEKMKLLPQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LERLRDPISLDCGHDFCIRCFSTHRLPGCEPPCCPECRKICKQKRGLRSLGEKMKLLPQR
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 PLPPALQETCPVRAEPLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLPPALQETCPVRAEPLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 GKSFLLNHLLQGLPGLESGEGGRPRGGEASLQGCRWGANGLARGIWMWSHPFLLGKEGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKSFLLNHLLQGLPGLESGEGGRPRGGEASLQGCRWGANGLARGIWMWSHPFLLGKEGKK
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 VAVFLVDTGDAMSPELSRETRIKLCALTTMLSSYQILSTSQELKDTDLDYLEMFVHVAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VAVFLVDTGDAMSPELSRETRIKLCALTTMLSSYQILSTSQELKDTDLDYLEMFVHVAEV
220 230 240 250 260 270
310 320 330 340 350
pF1KE1 MGKHYGMVPIQHLDLLVRDSSHPNKAGQGHVGNIFQ--------RLSGRYPKVQELLQGK
:::::::::::::::::::::::::::::::::::: ::::::::::::::::
XP_006 MGKHYGMVPIQHLDLLVRDSSHPNKAGQGHVGNIFQSTPLAASQRLSGRYPKVQELLQGK
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE1 RARCCLLPAPGRRRMNQGHASPGDTDDDFRHLLGAYVSDVLSAAPQHAKSRCQGYWNEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RARCCLLPAPGRRRMNQGHASPGDTDDDFRHLLGAYVSDVLSAAPQHAKSRCQGYWNEGR
340 350 360 370 380 390
420 430 440 450 460 470
pF1KE1 AVARGDRRLLTGQQLAQEIKNLSGWMGRTGPGFTSPDEMAAQLHDLRKVEAAKREFEEYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVARGDRRLLTGQQLAQEIKNLSGWMGRTGPGFTSPDEMAAQLHDLRKVEAAKREFEEYV
400 410 420 430 440 450
480 490 500 510 520 530
pF1KE1 RQQDVATKRIFSALRVLPDTMRNLLSTQKDAILARHGVALLCKGRDQTLEALEAELQATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQQDVATKRIFSALRVLPDTMRNLLSTQKDAILARHGVALLCKGRDQTLEALEAELQATA
460 470 480 490 500 510
540 550 560 570 580 590
pF1KE1 KAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAAEAGMVAAGAAVGATG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAAEAGMVAAGAAVGATG
520 530 540 550 560 570
600 610 620 630
pF1KE1 AAVVGGGVGAGLAATVGCMEKEEDERLLEGDREPLLQEE
:::::::::::::::::::::::::::::::::::::::
XP_006 AAVVGGGVGAGLAATVGCMEKEEDERLLEGDREPLLQEE
580 590 600 610
>>NP_001121185 (OMIM: 182600,606439,613708) atlastin-1 i (553 aa)
initn: 222 init1: 189 opt: 324 Z-score: 261.9 bits: 58.5 E(85289): 7.5e-08
Smith-Waterman score: 345; 29.4% identity (59.2% similar) in 289 aa overlap (127-394:24-306)
100 110 120 130 140 150
pF1KE1 CRKICKQKRGLRSLGEKMKLLPQRPLPPALQETCPVR-AEPLLLVRINASGGLILRMGAI
.: ::. : :. .. .. . .. : :.
NP_001 MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETAL
10 20 30 40 50
160 170 180 190 200 210
pF1KE1 NRCLKHPLARDTPVCLLAVLGEQHSGKSFLLNHLLQGLPGLES----GEGGRPRGGEASL
:: : .:: : ..: : ..:::::.. .:. . . :: :. ..: :
NP_001 NRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEP------L
60 70 80 90 100
220 230 240 250 260
pF1KE1 QGCRW--GANGLARGIWMWSHPFLLGK-EGKKVAVFLVDTGDAMSPELSRETRIKLCALT
: : :.. . :: .::. ::..: .::::::.:.:: ... . . . . ::.
NP_001 TGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALS
110 120 130 140 150 160
270 280 290 300 310 320
pF1KE1 TMLSSYQILSTSQELKDTDLDYLEMFVHVAEVMGKHYGMVPIQHLDLLVRDSSHPNKAGQ
::.:: :. . ::.... ::..:..:.. ... .. . :.: : .:::: : : . .
NP_001 TMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSY
170 180 190 200 210 220
330 340 350 360 370
pF1KE1 GHVGN---IFQRLSGRYPKVQELLQGKR--------ARCCLLPAPGRRRMNQGH--ASPG
: :. . .::. . .:: . .. : ::: :: . .. . ..
NP_001 GADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLK
230 240 250 260 270 280
380 390 400 410 420 430
pF1KE1 DTDDDFRHLLGAYVSDVLSAAPQHAKSRCQGYWNEGRAVARGDRRLLTGQQLAQEIKNLS
. ::.: . : . .::
NP_001 EIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSM
290 300 310 320 330 340
>>NP_853629 (OMIM: 182600,606439,613708) atlastin-1 isof (553 aa)
initn: 222 init1: 189 opt: 324 Z-score: 261.9 bits: 58.5 E(85289): 7.5e-08
Smith-Waterman score: 345; 29.4% identity (59.2% similar) in 289 aa overlap (127-394:24-306)
100 110 120 130 140 150
pF1KE1 CRKICKQKRGLRSLGEKMKLLPQRPLPPALQETCPVR-AEPLLLVRINASGGLILRMGAI
.: ::. : :. .. .. . .. : :.
NP_853 MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETAL
10 20 30 40 50
160 170 180 190 200 210
pF1KE1 NRCLKHPLARDTPVCLLAVLGEQHSGKSFLLNHLLQGLPGLES----GEGGRPRGGEASL
:: : .:: : ..: : ..:::::.. .:. . . :: :. ..: :
NP_853 NRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEP------L
60 70 80 90 100
220 230 240 250 260
pF1KE1 QGCRW--GANGLARGIWMWSHPFLLGK-EGKKVAVFLVDTGDAMSPELSRETRIKLCALT
: : :.. . :: .::. ::..: .::::::.:.:: ... . . . . ::.
NP_853 TGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALS
110 120 130 140 150 160
270 280 290 300 310 320
pF1KE1 TMLSSYQILSTSQELKDTDLDYLEMFVHVAEVMGKHYGMVPIQHLDLLVRDSSHPNKAGQ
::.:: :. . ::.... ::..:..:.. ... .. . :.: : .:::: : : . .
NP_853 TMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSY
170 180 190 200 210 220
330 340 350 360 370
pF1KE1 GHVGN---IFQRLSGRYPKVQELLQGKR--------ARCCLLPAPGRRRMNQGH--ASPG
: :. . .::. . .:: . .. : ::: :: . .. . ..
NP_853 GADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLK
230 240 250 260 270 280
380 390 400 410 420 430
pF1KE1 DTDDDFRHLLGAYVSDVLSAAPQHAKSRCQGYWNEGRAVARGDRRLLTGQQLAQEIKNLS
. ::.: . : . .::
NP_853 EIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSM
290 300 310 320 330 340
>>NP_056999 (OMIM: 182600,606439,613708) atlastin-1 isof (558 aa)
initn: 222 init1: 189 opt: 324 Z-score: 261.9 bits: 58.5 E(85289): 7.6e-08
Smith-Waterman score: 345; 29.4% identity (59.2% similar) in 289 aa overlap (127-394:24-306)
100 110 120 130 140 150
pF1KE1 CRKICKQKRGLRSLGEKMKLLPQRPLPPALQETCPVR-AEPLLLVRINASGGLILRMGAI
.: ::. : :. .. .. . .. : :.
NP_056 MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETAL
10 20 30 40 50
160 170 180 190 200 210
pF1KE1 NRCLKHPLARDTPVCLLAVLGEQHSGKSFLLNHLLQGLPGLES----GEGGRPRGGEASL
:: : .:: : ..: : ..:::::.. .:. . . :: :. ..: :
NP_056 NRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEP------L
60 70 80 90 100
220 230 240 250 260
pF1KE1 QGCRW--GANGLARGIWMWSHPFLLGK-EGKKVAVFLVDTGDAMSPELSRETRIKLCALT
: : :.. . :: .::. ::..: .::::::.:.:: ... . . . . ::.
NP_056 TGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALS
110 120 130 140 150 160
270 280 290 300 310 320
pF1KE1 TMLSSYQILSTSQELKDTDLDYLEMFVHVAEVMGKHYGMVPIQHLDLLVRDSSHPNKAGQ
::.:: :. . ::.... ::..:..:.. ... .. . :.: : .:::: : : . .
NP_056 TMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSY
170 180 190 200 210 220
330 340 350 360 370
pF1KE1 GHVGN---IFQRLSGRYPKVQELLQGKR--------ARCCLLPAPGRRRMNQGH--ASPG
: :. . .::. . .:: . .. : ::: :: . .. . ..
NP_056 GADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLK
230 240 250 260 270 280
380 390 400 410 420 430
pF1KE1 DTDDDFRHLLGAYVSDVLSAAPQHAKSRCQGYWNEGRAVARGDRRLLTGQQLAQEIKNLS
. ::.: . : . .::
NP_056 EIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSM
290 300 310 320 330 340
>>NP_001276977 (OMIM: 609369,615632) atlastin-3 isoform (523 aa)
initn: 274 init1: 183 opt: 293 Z-score: 238.5 bits: 54.0 E(85289): 1.5e-06
Smith-Waterman score: 322; 26.8% identity (53.3% similar) in 411 aa overlap (154-546:27-413)
130 140 150 160 170 180
pF1KE1 PALQETCPVRAEPLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHSGKS
:. : . :: : ...: : ..:::
NP_001 MESSKPGPVQVVLVQKDQHSFELDEKALASILLQDHIRDLDVVVVSVAGAFRKGKS
10 20 30 40 50
190 200 210 220 230
pF1KE1 FLLNHLLQGLPGL-ESGEGGRPRGGEASLQGCRW--GANGLARGIWMWSHPFLLGKEG-K
:.:. .:. : . :::... : : : : :.. . :: .::. : . : : :
NP_001 FILDFMLRYLYSQKESGHSNWLGDPEEPLTGFSWRGGSDPETTGIQIWSEVFTVEKPGGK
60 70 80 90 100 110
240 250 260 270 280 290
pF1KE1 KVAVFLVDTGDAMSPELSRETRIKLCALTTMLSSYQILSTSQELKDTDLDYLEMFVHVAE
:::: :.:: :.. . . . . ::.:: :: :: . ::.... ::. :..:.. ..
NP_001 KVAVVLMDTQGAFDSQSTVKDCATIFALSTMTSSVQIYNLSQNIQEDDLQQLQLFTEYGR
120 130 140 150 160 170
300 310 320 330 340 350
pF1KE1 VMGKHYGMVPIQHLDLLVRDSSHPNKAGQGHVGNI-F--QRLSGRYPKVQELLQGKRAR-
. . . :.: : .:::: : : . . : :.. : .::. . . .: .:. : .
NP_001 LAMDEIFQKPFQTLMFLVRDWSFPYEYSYGLQGGMAFLDKRLQVKEHQ-HEEIQNVRNHI
180 190 200 210 220 230
360 370 380 390 400
pF1KE1 --------CCLLPAPGRRRMNQGHASPGDTDDDFRHLLGAYVSDVLSAAPQ--HAKSRCQ
: ::: :: : .:: : : .. . : . .. . : . .. .
NP_001 HSCFSDVTCFLLPHPGL----QVATSP-DFDGKLKDIAGEFKEQLQALIPYVLNPSKLME
240 250 260 270 280 290
410 420 430 440 450 460
pF1KE1 GYWNEGRAVARGDRRLLTGQQLAQEIKNLSGWMGRTGPGFTSPDEMAAQLHDLRKVEAAK
: .... :: :: . . :: ..:. : : . .:. ..: . .::
NP_001 KEINGSKVTCRG---LL--EYFKAYIKI---YQGEDLPHPKSMLQATAEANNLAAAASAK
300 310 320 330 340
470 480 490 500 510 520
pF1KE1 REFEEYVRQQDVATKRIFSALRVLPDTMRNLLSTQKDAILARHGVALLCKGRDQTLEALE
. . ... . : .: :: ... :. : . . :.: ... .
NP_001 DIYYNNMEEVCGGEKPYLS-----PDILEEKHCEFKQLALDHFKKTKKMGGKDFSFR-YQ
350 360 370 380 390
530 540 550 560 570 580
pF1KE1 AELQATAKAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAAEAGMVAAG
::. : .... :: :
NP_001 QELEEEIKELYEN----FCKHNGSKNVFSTFRTPAVLFTGIVALYIASGLTGFIGLEVVA
400 410 420 430 440 450
>>NP_056274 (OMIM: 609369,615632) atlastin-3 isoform 1 [ (541 aa)
initn: 274 init1: 183 opt: 293 Z-score: 238.3 bits: 54.1 E(85289): 1.6e-06
Smith-Waterman score: 322; 26.8% identity (53.3% similar) in 411 aa overlap (154-546:45-431)
130 140 150 160 170 180
pF1KE1 PALQETCPVRAEPLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHSGKS
:. : . :: : ...: : ..:::
NP_056 ADDAMESSKPGPVQVVLVQKDQHSFELDEKALASILLQDHIRDLDVVVVSVAGAFRKGKS
20 30 40 50 60 70
190 200 210 220 230
pF1KE1 FLLNHLLQGLPGL-ESGEGGRPRGGEASLQGCRW--GANGLARGIWMWSHPFLLGKEG-K
:.:. .:. : . :::... : : : : :.. . :: .::. : . : : :
NP_056 FILDFMLRYLYSQKESGHSNWLGDPEEPLTGFSWRGGSDPETTGIQIWSEVFTVEKPGGK
80 90 100 110 120 130
240 250 260 270 280 290
pF1KE1 KVAVFLVDTGDAMSPELSRETRIKLCALTTMLSSYQILSTSQELKDTDLDYLEMFVHVAE
:::: :.:: :.. . . . . ::.:: :: :: . ::.... ::. :..:.. ..
NP_056 KVAVVLMDTQGAFDSQSTVKDCATIFALSTMTSSVQIYNLSQNIQEDDLQQLQLFTEYGR
140 150 160 170 180 190
300 310 320 330 340 350
pF1KE1 VMGKHYGMVPIQHLDLLVRDSSHPNKAGQGHVGNI-F--QRLSGRYPKVQELLQGKRAR-
. . . :.: : .:::: : : . . : :.. : .::. . . .: .:. : .
NP_056 LAMDEIFQKPFQTLMFLVRDWSFPYEYSYGLQGGMAFLDKRLQVKEHQ-HEEIQNVRNHI
200 210 220 230 240 250
360 370 380 390 400
pF1KE1 --------CCLLPAPGRRRMNQGHASPGDTDDDFRHLLGAYVSDVLSAAPQ--HAKSRCQ
: ::: :: : .:: : : .. . : . .. . : . .. .
NP_056 HSCFSDVTCFLLPHPGL----QVATSP-DFDGKLKDIAGEFKEQLQALIPYVLNPSKLME
260 270 280 290 300
410 420 430 440 450 460
pF1KE1 GYWNEGRAVARGDRRLLTGQQLAQEIKNLSGWMGRTGPGFTSPDEMAAQLHDLRKVEAAK
: .... :: :: . . :: ..:. : : . .:. ..: . .::
NP_056 KEINGSKVTCRG---LL--EYFKAYIKI---YQGEDLPHPKSMLQATAEANNLAAAASAK
310 320 330 340 350 360
470 480 490 500 510 520
pF1KE1 REFEEYVRQQDVATKRIFSALRVLPDTMRNLLSTQKDAILARHGVALLCKGRDQTLEALE
. . ... . : .: :: ... :. : . . :.: ... .
NP_056 DIYYNNMEEVCGGEKPYLS-----PDILEEKHCEFKQLALDHFKKTKKMGGKDFSFR-YQ
370 380 390 400 410
530 540 550 560 570 580
pF1KE1 AELQATAKAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAAEAGMVAAG
::. : .... :: :
NP_056 QELEEEIKELYEN----FCKHNGSKNVFSTFRTPAVLFTGIVALYIASGLTGFIGLEVVA
420 430 440 450 460 470
>>NP_071769 (OMIM: 609368) atlastin-2 isoform 1 [Homo sa (579 aa)
initn: 263 init1: 172 opt: 288 Z-score: 234.2 bits: 53.4 E(85289): 2.6e-06
Smith-Waterman score: 335; 25.0% identity (55.3% similar) in 488 aa overlap (109-567:38-496)
80 90 100 110 120 130
pF1KE1 RCFSTHRLPGCEPPCCPECRKICKQKRGLRSLGEKMKLLPQRPLPPALQETCPVRAEPLL
::::... .... :::. ..
NP_071 ARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCPVQ---IV
10 20 30 40 50 60
140 150 160 170 180 190
pF1KE1 LVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHSGKSFLLNHLLQGLPGLES
:.. . . .. : :... : . :: . ...: : ..::::::. .:. . . .:
NP_071 LAHED-DHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDS
70 80 90 100 110 120
200 210 220 230 240 250
pF1KE1 GEGGRPRGGEASLQGCRW--GANGLARGIWMWSHPFLLGK-EGKKVAVFLVDTGDAMSPE
. :.. : : : : . . :: .:.. :.. . .: ::::.:.:: :.. .
NP_071 --QSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDSQ
130 140 150 160 170 180
260 270 280 290 300 310
pF1KE1 LSRETRIKLCALTTMLSSYQILSTSQELKDTDLDYLEMFVHVAEVMGKHYGMVPIQHLDL
. . . ::.:: :: :. . ::.... ::..:..:.. ... .. . :.: : .
NP_071 STIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMF
190 200 210 220 230 240
320 330 340 350 360
pF1KE1 LVRDSSHPNKAGQGHVGN---IFQRLSGRYPKVQELLQGKRAR---------CCLLPAPG
:.:: :.: . . : :. . .::. . . .:: :. : . : ::: ::
NP_071 LIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEEL-QNVRKHIHNCFSNLGCFLLPHPG
250 260 270 280 290 300
370 380 390 400 410 420
pF1KE1 RRRMNQGHASPG---DTDDDFRHLLGAYVSDVLSAAPQHAKSRCQGYWNEGRAVARGDRR
. . . . : : :.::.. : : .: ::. : . :..
NP_071 LK-VATNPSFDGRLKDIDEDFKRELRNLVPLLL--APE----------NLVEKEISGSK-
310 320 330 340
430 440 450 460 470
pF1KE1 LLTGQQLAQEIKN-LSGWMGRTGPGFTSPDEMAAQLHDLRKVEAAKREFEEYVRQQDVAT
.: ..:.. .: .. ..:. : : . .:. ..: : .:. . . ..: .
NP_071 -VTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGD
350 360 370 380 390 400
480 490 500 510 520 530
pF1KE1 KRIFSALRVLPDTMRNLLSTQKDAI-----LARHGVALLCKGRDQTLEALEAELQATAKA
: .. : :. :. .. :: . . : .:. : : . ::::.. :
NP_071 KPYIAP----SDLERKHLDLKEVAIKQFRSVKKMGGDEFCR-RYQ--DQLEAEIEETYAN
410 420 430 440 450
540 550 560 570 580
pF1KE1 FM---DSYTMRFCGHLAAVGGAVGAGLMGLAG--GVVGAGMAAAALAAEAGMVAAGAAVG
:. :. .. . .. :. :: ... ..: : .:
NP_071 FIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTW
460 470 480 490 500 510
590 600 610 620 630
pF1KE1 ATGAAVVGGGVGAGLAATVGCMEKEEDERLLEGDREPLLQEE
NP_071 AYVKYSGEFREIGTVIDQIAETLWEQVFSKLFEVTRRRMVHRALSSAQRQRLSSNNNKKK
520 530 540 550 560 570
631 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:31:26 2016 done: Mon Nov 7 03:31:28 2016
Total Scan time: 10.830 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]