Result of FASTA (omim) for
pFN21AE1120
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1120, 364 aa
1>>>pF1KE1120 364 - 364 aa - 364 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.1446+/-0.000385; mu= 23.7456+/- 0.025
mean_var=101.8230+/-26.632, 0's: 0 Z-trim(112.9): 536 B-trim: 2230 in 2/50
Lambda= 0.127102
statistics sampled from 21239 (22005) to 21239 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.258), width: 16
Scan time: 7.520
The best scores are: opt bits E(85289)
NP_000504 (OMIM: 300821,303700,303800) medium-wave ( 364) 2496 468.7 9.4e-132
NP_064445 (OMIM: 300822,303700,303900) long-wave-s ( 364) 2427 456.0 6.1e-128
NP_001699 (OMIM: 190900,613522) short-wave-sensiti ( 348) 1033 200.4 5.3e-51
NP_000530 (OMIM: 136880,180380,610445,613731) rhod ( 348) 1002 194.7 2.7e-49
NP_055137 (OMIM: 606695) opsin-3 [Homo sapiens] ( 402) 512 104.9 3.3e-22
NP_006574 (OMIM: 605224) visual pigment-like recep ( 337) 507 103.9 5.6e-22
NP_859528 (OMIM: 609042) opsin-5 [Homo sapiens] ( 354) 446 92.7 1.3e-18
XP_016865905 (OMIM: 609042) PREDICTED: opsin-5 iso ( 408) 446 92.8 1.4e-18
XP_016865900 (OMIM: 609042) PREDICTED: opsin-5 iso ( 298) 409 85.8 1.3e-16
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 382 81.2 5.3e-15
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 382 81.3 5.6e-15
XP_016872446 (OMIM: 606665) PREDICTED: melanopsin ( 405) 361 77.2 7.1e-14
NP_001025186 (OMIM: 606665) melanopsin isoform 2 [ ( 489) 361 77.4 7.8e-14
XP_016872444 (OMIM: 606665) PREDICTED: melanopsin ( 539) 361 77.4 8.2e-14
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 350 75.2 2.8e-13
NP_005949 (OMIM: 600665) melatonin receptor type 1 ( 350) 346 74.4 4.4e-13
NP_001050 (OMIM: 162332,614840) neuromedin-K recep ( 465) 338 73.1 1.4e-12
NP_001049 (OMIM: 162323) substance-P receptor isof ( 407) 327 71.0 5.3e-12
NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 326 70.7 5.7e-12
NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 326 70.7 5.7e-12
XP_016865902 (OMIM: 609042) PREDICTED: opsin-5 iso ( 285) 324 70.2 6.5e-12
XP_016865901 (OMIM: 609042) PREDICTED: opsin-5 iso ( 285) 324 70.2 6.5e-12
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 323 70.2 8.4e-12
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 314 68.6 2.7e-11
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 314 68.6 2.7e-11
NP_056542 (OMIM: 162323) substance-P receptor isof ( 311) 313 68.3 2.7e-11
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 314 68.6 2.7e-11
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 314 68.6 2.8e-11
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 314 68.6 2.8e-11
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 314 68.6 2.8e-11
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 314 68.6 2.8e-11
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 314 68.6 2.8e-11
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 314 68.6 2.8e-11
NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 314 68.7 2.9e-11
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 313 68.4 3e-11
NP_004215 (OMIM: 300207) melatonin-related recepto ( 617) 315 69.1 3.1e-11
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 314 68.8 3.1e-11
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 314 68.8 3.1e-11
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 313 68.4 3.2e-11
NP_005950 (OMIM: 125853,600804) melatonin receptor ( 362) 307 67.3 6.4e-11
XP_011541141 (OMIM: 125853,600804) PREDICTED: mela ( 362) 307 67.3 6.4e-11
XP_016865898 (OMIM: 609042) PREDICTED: opsin-5 iso ( 303) 305 66.8 7.5e-11
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349) 304 66.7 9.2e-11
NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 303 66.5 1.1e-10
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 302 66.4 1.3e-10
NP_115940 (OMIM: 176400,604161,614837) kiSS-1 rece ( 398) 300 66.0 1.6e-10
XP_016874309 (OMIM: 602351) PREDICTED: chemokine-l ( 371) 299 65.8 1.8e-10
NP_004063 (OMIM: 602351) chemokine-like receptor 1 ( 371) 299 65.8 1.8e-10
NP_001135816 (OMIM: 602351) chemokine-like recepto ( 373) 299 65.8 1.8e-10
NP_001135815 (OMIM: 602351) chemokine-like recepto ( 373) 299 65.8 1.8e-10
>>NP_000504 (OMIM: 300821,303700,303800) medium-wave-sen (364 aa)
initn: 2496 init1: 2496 opt: 2496 Z-score: 2486.4 bits: 468.7 E(85289): 9.4e-132
Smith-Waterman score: 2496; 100.0% identity (100.0% similar) in 364 aa overlap (1-364:1-364)
10 20 30 40 50 60
pF1KE1 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 PLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS
310 320 330 340 350 360
pF1KE1 VSPA
::::
NP_000 VSPA
>>NP_064445 (OMIM: 300822,303700,303900) long-wave-sensi (364 aa)
initn: 2427 init1: 2427 opt: 2427 Z-score: 2418.0 bits: 456.0 E(85289): 6.1e-128
Smith-Waterman score: 2427; 96.4% identity (98.6% similar) in 364 aa overlap (1-364:1-364)
10 20 30 40 50 60
pF1KE1 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFV
:::: :::::::::::::::::::::::::::::::::::::::::::::.:::: ::::
NP_064 IFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYL
::::::::::::::::::::::::::::::::::::::::::::::::: ::.::.::::
NP_064 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFH
:::::::::::::::::::::::::::::::::..:.: :::::.:::::::::::: ::
NP_064 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 PLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS
310 320 330 340 350 360
pF1KE1 VSPA
::::
NP_064 VSPA
>>NP_001699 (OMIM: 190900,613522) short-wave-sensitive o (348 aa)
initn: 1052 init1: 963 opt: 1033 Z-score: 1036.7 bits: 200.4 E(85289): 5.3e-51
Smith-Waterman score: 1033; 44.3% identity (74.8% similar) in 345 aa overlap (23-363:5-347)
10 20 30 40 50 60
pF1KE1 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM
.. .. . : .:. ::..::.::::: :...: ...:
NP_001 MRKMSEEEFYLFKNISSV-GPWDGPQYHIAPVWAFYLQAAFM
10 20 30 40
70 80 90 100 110 120
pF1KE1 IFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFV
: . . :..::.::...::::.:::.::::.. . . ... : . ::::
NP_001 GTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFSVFPVFVASCNGYFV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWA
.:. .:.:::. .. :.. ::::....::..:.:::::: ::..: :.. . .: .
NP_001 FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNFRFSSKHALTVVLATWTIG
110 120 130 140 150 160
190 200 210 220 230
pF1KE1 AVWTAPPIFGWSRYWPHGLKTSCGPDVFS-GSSYPGVQSYMIVLMVTCCITPLSIIVLCY
. ::.:::::. :.::. ::::: .. :..: . .:: :.. : :.:::.: . :
NP_001 IGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRS-ESYTWFLFIFCFIVPLSLICFSY
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 LQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPF
:. :..::: ::.:: .:::::.::.::::::: .:: :. ::: :: . . : .. .
NP_001 TQLLRALKAVAAQQQESATTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNHGL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 HPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLF-GKKVDDGSELSSASKTEVSSV
....:.::.::: ::::.:: :::.::. ::... :: . : :. :..:::::.:
NP_001 DLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMVCGKAMTDESDTCSSQKTEVSTV
290 300 310 320 330 340
360
pF1KE1 SS--VSPA
:: :.:
NP_001 SSTQVGPN
>>NP_000530 (OMIM: 136880,180380,610445,613731) rhodopsi (348 aa)
initn: 977 init1: 977 opt: 1002 Z-score: 1006.0 bits: 194.7 E(85289): 2.7e-49
Smith-Waterman score: 1002; 44.3% identity (74.2% similar) in 345 aa overlap (21-359:2-346)
10 20 30 40 50
pF1KE1 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNST---RGPFEGPNYHIAPRWVYHLTS
..:.. : ::.: :.::: :.:..: : . . .
NP_000 MNGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLA
10 20 30 40
60 70 80 90 100 110
pF1KE1 VWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYG
..:..... . : :.: .:.. :::: :::.::.::::::: .. . : .. ....:
NP_000 AYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHG
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 YFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSW
:::.: : :::. ..: : .::::.... ::..:::::..: :: . ::.:.::.:
NP_000 YFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTW
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 IWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVL
. : . .:::. ::::: :.::. ::: : .. . . .:..: ..:. :. :: .
NP_000 VMALACAAPPLAGWSRYIPEGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIIIFF
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 CYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGY
:: :. .... .: ::.:: .::::::::::::..::.:: .:: ::: : . .. :
NP_000 CYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWVPYASVAFYIFTHQGS
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 PFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLF--GKK-VDDGSELSSASKTE
: :.. ..::::::::.:::::::..::.:::::.: . ::. . : ...::::
NP_000 NFGPIFMTIPAFFAKSAAIYNPVIYIMMNKQFRNCMLTTICCGKNPLGDDEASATVSKTE
290 300 310 320 330 340
360
pF1KE1 VSSVSSVSPA
.:.:.
NP_000 TSQVAPA
>>NP_055137 (OMIM: 606695) opsin-3 [Homo sapiens] (402 aa)
initn: 523 init1: 223 opt: 512 Z-score: 519.8 bits: 104.9 E(85289): 3.3e-22
Smith-Waterman score: 512; 30.9% identity (64.3% similar) in 311 aa overlap (38-337:23-324)
10 20 30 40 50 60
pF1KE1 QRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRW---VYHLTSVWMIFVV
:: . . :: . .:. .. . .
NP_055 MYSGNRSGGHGYWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIG
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 IASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFVLGHP
. .: .: :::. .::..:: : . .:::....:: .... :.. :. . . .:
NP_055 LLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 MCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWAAVWT
:: .:.. :: ::... .:.....::.. : . . :. : .:.. :... .:.
NP_055 GCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHAR-VINFS--WAWRAITYIWLYSLAWA
120 130 140 150 160
190 200 210 220 230 240
pF1KE1 APPIFGWSRYW--PHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQV
. :..::.:: ::: .: : : .. .:... :.. : ..::..:. :: ..
NP_055 GAPLLGWNRYILDVHGL--GCTVDWKSKDAND--SSFVLFLFLGCLVVPLGVIAHCYGHI
170 180 190 200 210 220
250 260 270 280 290
pF1KE1 WLAIRAVAKQQKESESTQ-----KAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANP-G
.:: . . .. .. : : ::....: .:...: :: :: . :: ..: :
NP_055 LYSIRML-RCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPY-IVICFLVVNGHG
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 YPFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVS
. : .. . .:::: :.::::::::: :.:: .:::.
NP_055 HLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGS
290 300 310 320 330 340
360
pF1KE1 SVSSVSPA
NP_055 EMQIRPIVMSQKDGDRPKKKVTFNSSSIIFIITSDESLSVDDSDKTNGSKVDVIQVRPL
350 360 370 380 390 400
>>NP_006574 (OMIM: 605224) visual pigment-like receptor (337 aa)
initn: 425 init1: 425 opt: 507 Z-score: 515.6 bits: 103.9 E(85289): 5.6e-22
Smith-Waterman score: 507; 28.3% identity (65.1% similar) in 307 aa overlap (53-356:25-328)
30 40 50 60 70 80
pF1KE1 TQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVIASVFTNGLVLAATMKFK
........:.. . :...: .::. .:.:
NP_006 MLRNNLGNSSDSKNEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYK
10 20 30 40 50
90 100 110 120 130 140
pF1KE1 KLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFVLGHPMC-VLEGYTVSLCGITGL
.:: : : :..::::.:.. . :. .:.....:: . .:. : : : .. . :....
NP_006 ELRTPTNAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNI-FFGMASI
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE1 WSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWAAVWTAPPIFGWSRYWPHGLKT
:.... .:....: : . :. .. : : .:: . :. ::.::. : : .
NP_006 GLLTVVAVDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGA
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE1 SCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRA-VAKQQKESESTQ
.: . ... . :: ..... :.::... :: .: :.:. .... :: . .
NP_006 TCTINWRKNDR--SFVSYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRD
180 190 200 210 220 230
270 280 290 300 310
pF1KE1 KAEK-EVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFHPLMAALPAFFAKSATIYNP
... .::.: :.:. : :.::.. .:. . . : :: . .::::.:.:::
NP_006 WSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNP
240 250 260 270 280 290
320 330 340 350 360
pF1KE1 VIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSSVSPA
::: :..:: .: .: .. . ..: .::
NP_006 CIYVVANKKFRRAMLAMFKCQTHQTMPVTSILPMDVSQNPLASGRI
300 310 320 330
>>NP_859528 (OMIM: 609042) opsin-5 [Homo sapiens] (354 aa)
initn: 409 init1: 282 opt: 446 Z-score: 454.9 bits: 92.7 E(85289): 1.3e-18
Smith-Waterman score: 446; 26.2% identity (61.2% similar) in 317 aa overlap (51-357:30-344)
30 40 50 60 70
pF1KE1 DSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVV-IASVFTNGLVLAATM
: :.. ... .. : :.: :: :: .
NP_859 MALNHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSS
10 20 30 40 50
80 90 100 110 120 130
pF1KE1 KFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFVLGHPMCVLEGYTVSLCGIT
. :: .: . . .:::: ::. .:... ..... .:.: : :.. . :
NP_859 RRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCG
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE1 GLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWAAVWTAPPIFGWSRYWPHGL
.: ... .: .:.. .: .: . : : . .: : .:. ::. :. : . : :. .
NP_859 SLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPF
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE1 KTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQ----QKE
::: : . ... : : ... .. : . : ..::. :... ... .:. ...
NP_859 GTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSR
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE1 SESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFH-PL-MAALPAFFAKS
.:.. : ..:...... .: . : ::: . ..: : : :. ....:...:::
NP_859 IHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAF--GRPDSIPIQLSVVPTLLAKS
240 250 260 270 280 290
320 330 340 350 360
pF1KE1 ATIYNPVIYVFMNRQFRNCI---LQLFGKKVDDGSELSSASKTEVSSVSSVSPA
:..:::.:: .. .: : :. :: .: .: ... .. ::
NP_859 AAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSAVLEIHEEWE
300 310 320 330 340 350
>>XP_016865905 (OMIM: 609042) PREDICTED: opsin-5 isoform (408 aa)
initn: 409 init1: 282 opt: 446 Z-score: 454.3 bits: 92.8 E(85289): 1.4e-18
Smith-Waterman score: 446; 26.2% identity (61.2% similar) in 317 aa overlap (51-357:30-344)
30 40 50 60 70
pF1KE1 DSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVV-IASVFTNGLVLAATM
: :.. ... .. : :.: :: :: .
XP_016 MALNHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSS
10 20 30 40 50
80 90 100 110 120 130
pF1KE1 KFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFVLGHPMCVLEGYTVSLCGIT
. :: .: . . .:::: ::. .:... ..... .:.: : :.. . :
XP_016 RRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCG
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE1 GLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWAAVWTAPPIFGWSRYWPHGL
.: ... .: .:.. .: .: . : : . .: : .:. ::. :. : . : :. .
XP_016 SLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPF
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE1 KTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQ----QKE
::: : . ... : : ... .. : . : ..::. :... ... .:. ...
XP_016 GTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSR
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE1 SESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFH-PL-MAALPAFFAKS
.:.. : ..:...... .: . : ::: . ..: : : :. ....:...:::
XP_016 IHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAF--GRPDSIPIQLSVVPTLLAKS
240 250 260 270 280 290
320 330 340 350 360
pF1KE1 ATIYNPVIYVFMNRQFRNCI---LQLFGKKVDDGSELSSASKTEVSSVSSVSPA
:..:::.:: .. .: : :. :: .: .: ... .. ::
XP_016 AAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSAVLEIHEEDKGRL
300 310 320 330 340 350
XP_016 WHQLSCGENSEMTASSETLGTKAHSPLQETREGENEAVGGNNKCSGCEECI
360 370 380 390 400
>>XP_016865900 (OMIM: 609042) PREDICTED: opsin-5 isoform (298 aa)
initn: 388 init1: 261 opt: 409 Z-score: 419.0 bits: 85.8 E(85289): 1.3e-16
Smith-Waterman score: 409; 26.7% identity (61.8% similar) in 285 aa overlap (82-357:7-288)
60 70 80 90 100 110
pF1KE1 VYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISV
:::: : . . .:::: ::. .:... ...
XP_016 MSSRRKKKLR-PAEIMTINLAVCDLGISVVGKPFTI
10 20 30
120 130 140 150 160 170
pF1KE1 VNQVYGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIV
.. .:.: : :.. . : .: ... .: .:.. .: .: . : : .
XP_016 ISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYI
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE1 GIAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITP
.: : .:. ::. :. : . : :. . ::: : . ... : : ... .. : . :
XP_016 CLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLP
100 110 120 130 140 150
240 250 260 270 280
pF1KE1 LSIIVLCYLQVWLAIRAVAKQ----QKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFF
..::. :... ... .:. ... .:.. : ..:...... .: . : :::
XP_016 TAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVV
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE1 ACFAAANPGYPFH-PL-MAALPAFFAKSATIYNPVIYVFMNRQFRNCI---LQLFGKKVD
. ..: : : :. ....:...::::..:::.:: .. .: : :. ::
XP_016 SVWSAF--GRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSL
220 230 240 250 260 270
350 360
pF1KE1 DGSELSSASKTEVSSVSSVSPA
.: .: ... .. ::
XP_016 EGFRLHTVTTVRKSSAVLEIHEEWE
280 290
>>NP_150598 (OMIM: 606665) melanopsin isoform 1 [Homo sa (478 aa)
initn: 426 init1: 144 opt: 382 Z-score: 390.3 bits: 81.2 E(85289): 5.3e-15
Smith-Waterman score: 514; 28.6% identity (63.9% similar) in 346 aa overlap (18-335:27-363)
10 20 30 40
pF1KE1 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTY----TNSNSTRGPFEG-----
:. ::.:::: . . : .. : . .
NP_150 MNPPSGPRVPPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 PNYHIAPRWVYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAE
:. . . : : .: ...: ..... : :. . . ..:: : : ...::::.:.
NP_150 PTVDVPDHAHYTLGTV-ILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLM
70 80 90 100 110
110 120 130 140 150
pF1KE1 TVIASTISVVNQVYGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKP---F
. . . ....: ...:. : . .. .: ::... .:. :. .:..:. .: :
NP_150 SFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATF
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE1 GNV-RFDAKLAIVGIAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQS
: . . : ....:. :..: .:. ::.:::: : :.:: :::. : .: . :.:..
NP_150 GVASKRRAAFVLLGV---WLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFT--PAVRA
180 190 200 210 220 230
220 230 240 250 260
pF1KE1 YMIVLMVTCCIT---PLSIIVLCYLQVWLAIRAVAKQQK-------ESEST---QKAEKE
: ..: ::.. :: ::. ::. .. ::: ... . ..:: :. ..:
NP_150 YTMLL---CCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSE
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE1 --VTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFHPLMAALPAFFAKSATIYNPVIYV
.........: : . :.::. : : :. .. . : :...:: .::...:.::.::.
NP_150 CKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYA
300 310 320 330 340 350
330 340 350 360
pF1KE1 FMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSSVSPA
. . ..: : :
NP_150 ITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQES
360 370 380 390 400 410
364 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 18:01:20 2016 done: Mon Nov 7 18:01:21 2016
Total Scan time: 7.520 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]