Result of FASTA (omim) for
pFN21AE1112
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1112, 142 aa
1>>>pF1KE1112 142 - 142 aa - 142 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4767+/-0.000365; mu= 9.7288+/- 0.023
mean_var=57.5342+/-11.492, 0's: 0 Z-trim(112.7): 23 B-trim: 256 in 2/50
Lambda= 0.169087
statistics sampled from 21746 (21769) to 21746 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.255), width: 16
Scan time: 4.770
The best scores are: opt bits E(85289)
NP_000508 (OMIM: 140700,141850,604131,613978) hemo ( 142) 925 233.8 7.4e-62
NP_000549 (OMIM: 140700,141800,604131,613978) hemo ( 142) 925 233.8 7.4e-62
NP_005322 (OMIM: 142240) hemoglobin subunit theta- ( 142) 588 151.5 4.1e-37
XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin ( 142) 563 145.4 2.8e-35
NP_005323 (OMIM: 142310) hemoglobin subunit zeta [ ( 142) 563 145.4 2.8e-35
XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin ( 154) 563 145.5 3e-35
NP_001003938 (OMIM: 609639) hemoglobin subunit mu ( 141) 430 113.0 1.6e-25
NP_000509 (OMIM: 140700,141749,141900,603902,60390 ( 147) 381 101.1 6.8e-22
NP_000510 (OMIM: 142000) hemoglobin subunit delta ( 147) 373 99.1 2.6e-21
NP_000175 (OMIM: 141749,142250,613977) hemoglobin ( 147) 366 97.4 8.5e-21
NP_000550 (OMIM: 141749,142200) hemoglobin subunit ( 147) 363 96.7 1.4e-20
NP_005321 (OMIM: 142100) hemoglobin subunit epsilo ( 147) 332 89.1 2.7e-18
NP_976311 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 180 52.0 4.1e-07
XP_005261662 (OMIM: 160000) PREDICTED: myoglobin i ( 154) 180 52.0 4.1e-07
NP_005359 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 180 52.0 4.1e-07
NP_976312 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 180 52.0 4.1e-07
XP_016879605 (OMIM: 608759) PREDICTED: cytoglobin ( 137) 141 42.5 0.00027
NP_599030 (OMIM: 608759) cytoglobin [Homo sapiens] ( 190) 141 42.5 0.00036
XP_005257062 (OMIM: 608759) PREDICTED: cytoglobin ( 202) 141 42.5 0.00038
>>NP_000508 (OMIM: 140700,141850,604131,613978) hemoglob (142 aa)
initn: 925 init1: 925 opt: 925 Z-score: 1231.5 bits: 233.8 E(85289): 7.4e-62
Smith-Waterman score: 925; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE1 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTP
70 80 90 100 110 120
130 140
pF1KE1 AVHASLDKFLASVSTVLTSKYR
::::::::::::::::::::::
NP_000 AVHASLDKFLASVSTVLTSKYR
130 140
>>NP_000549 (OMIM: 140700,141800,604131,613978) hemoglob (142 aa)
initn: 925 init1: 925 opt: 925 Z-score: 1231.5 bits: 233.8 E(85289): 7.4e-62
Smith-Waterman score: 925; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE1 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTP
70 80 90 100 110 120
130 140
pF1KE1 AVHASLDKFLASVSTVLTSKYR
::::::::::::::::::::::
NP_000 AVHASLDKFLASVSTVLTSKYR
130 140
>>NP_005322 (OMIM: 142240) hemoglobin subunit theta-1 [H (142 aa)
initn: 588 init1: 588 opt: 588 Z-score: 787.2 bits: 151.5 E(85289): 4.1e-37
Smith-Waterman score: 588; 62.0% identity (87.3% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE1 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHG
:.:: :.. :.: : :.:...: : .::::: ::.::.::::: :.::: ::.::..::
NP_005 MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYFSHLDLSPGSSQVRAHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTP
.::::::. :: ..::.:.:::::: ::: .:::::..:.::.:::::::: : :..:.:
NP_005 QKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARHYPGDFSP
70 80 90 100 110 120
130 140
pF1KE1 AVHASLDKFLASVSTVLTSKYR
:..:::::::. : ..:.:.::
NP_005 ALQASLDKFLSHVISALVSEYR
130 140
>>XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin subu (142 aa)
initn: 563 init1: 563 opt: 563 Z-score: 754.3 bits: 145.4 E(85289): 2.8e-35
Smith-Waterman score: 563; 59.9% identity (83.1% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE1 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHG
: :. ...: . . :.:....: :.:.:::.::: : :::::::::: ::::...::
XP_005 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFDLHPGSAQLRAHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTP
.::. :. .:: .::. .::: ::.:::. :::::::::::::::::::::..::.::
XP_005 SKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPADFTA
70 80 90 100 110 120
130 140
pF1KE1 AVHASLDKFLASVSTVLTSKYR
.::. ::::. ::.::: :::
XP_005 EAHAAWDKFLSVVSSVLTEKYR
130 140
>>NP_005323 (OMIM: 142310) hemoglobin subunit zeta [Homo (142 aa)
initn: 563 init1: 563 opt: 563 Z-score: 754.3 bits: 145.4 E(85289): 2.8e-35
Smith-Waterman score: 563; 59.9% identity (83.1% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE1 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHG
: :. ...: . . :.:....: :.:.:::.::: : :::::::::: ::::...::
NP_005 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFDLHPGSAQLRAHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTP
.::. :. .:: .::. .::: ::.:::. :::::::::::::::::::::..::.::
NP_005 SKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPADFTA
70 80 90 100 110 120
130 140
pF1KE1 AVHASLDKFLASVSTVLTSKYR
.::. ::::. ::.::: :::
NP_005 EAHAAWDKFLSVVSSVLTEKYR
130 140
>>XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin subu (154 aa)
initn: 563 init1: 563 opt: 563 Z-score: 753.7 bits: 145.5 E(85289): 3e-35
Smith-Waterman score: 563; 59.9% identity (83.1% similar) in 142 aa overlap (1-142:13-154)
10 20 30 40
pF1KE1 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFD
: :. ...: . . :.:....: :.:.:::.::: : :::::::::
XP_005 MTCFFDAAHPAAMSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFD
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 LSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLV
: ::::...::.::. :. .:: .::. .::: ::.:::. :::::::::::::::::
XP_005 LHPGSAQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLV
70 80 90 100 110 120
110 120 130 140
pF1KE1 TLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
::::..::.:: .::. ::::. ::.::: :::
XP_005 TLAARFPADFTAEAHAAWDKFLSVVSSVLTEKYR
130 140 150
>>NP_001003938 (OMIM: 609639) hemoglobin subunit mu [Hom (141 aa)
initn: 430 init1: 430 opt: 430 Z-score: 579.0 bits: 113.0 E(85289): 1.6e-25
Smith-Waterman score: 430; 45.4% identity (75.9% similar) in 141 aa overlap (2-142:1-141)
10 20 30 40 50 60
pF1KE1 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHG
.:: ..... .: ...: ...::: : :.: .:.::.::::.. . ..:. .::
NP_001 MLSAQERAQIAQVWDLIAGHEAQFGAELLLRLFTVYPSTKVYFPHLSACQDATQLLSHG
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 KKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTP
... :. :: :::.. ::: :.:::: :::::.:: :: .:. :.::.:: :::
NP_001 QRMLAAVGAAVQHVDNLRAALSPLADLHALVLRVDPANFPLLIQCFHVVLASHLQDEFTV
60 70 80 90 100 110
130 140
pF1KE1 AVHASLDKFLASVSTVLTSKYR
..:. ::::..:..::: :::
NP_001 QMQAAWDKFLTGVAVVLTEKYR
120 130 140
>>NP_000509 (OMIM: 140700,141749,141900,603902,603903,60 (147 aa)
initn: 325 init1: 273 opt: 381 Z-score: 514.1 bits: 101.1 E(85289): 6.8e-22
Smith-Waterman score: 381; 43.4% identity (74.5% similar) in 145 aa overlap (3-141:4-146)
10 20 30 40 50
pF1KE1 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLS-----HGS
:.: .:. : : :::: .. : :.::: :... .: :. .: : ::: :.
NP_000 MVHLTPEEKSAVTALWGKV--NVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGN
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 AQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAH
.::.::::: :.....::.:.. .....::.:: ::.::: ::.::.. :. .:: :
NP_000 PKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHH
60 70 80 90 100 110
120 130 140
pF1KE1 LPAEFTPAVHASLDKFLASVSTVLTSKYR
. :::: :.:. .: .:.:...:. ::
NP_000 FGKEFTPPVQAAYQKVVAGVANALAHKYH
120 130 140
>>NP_000510 (OMIM: 142000) hemoglobin subunit delta [Hom (147 aa)
initn: 305 init1: 263 opt: 373 Z-score: 503.5 bits: 99.1 E(85289): 2.6e-21
Smith-Waterman score: 373; 43.4% identity (74.5% similar) in 145 aa overlap (3-141:4-146)
10 20 30 40 50
pF1KE1 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLSH-----GS
:.: .:: :.: ::::.. : :.::: :... .: :. .: : ::: :.
NP_000 MVHLTPEEKTAVNALWGKVNVDA--VGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGN
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 AQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAH
.::.::::: :.....::.:.. ...: ::.:: ::.::: ::.::.. :. .:: .
NP_000 PKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARN
60 70 80 90 100 110
120 130 140
pF1KE1 LPAEFTPAVHASLDKFLASVSTVLTSKYR
. :::: ..:. .: .:.:...:. ::
NP_000 FGKEFTPQMQAAYQKVVAGVANALAHKYH
120 130 140
>>NP_000175 (OMIM: 141749,142250,613977) hemoglobin subu (147 aa)
initn: 314 init1: 277 opt: 366 Z-score: 494.3 bits: 97.4 E(85289): 8.5e-21
Smith-Waterman score: 366; 41.4% identity (75.9% similar) in 145 aa overlap (3-141:4-146)
10 20 30 40 50
pF1KE1 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLSHGSA----
.. ::... . ::::... . :.:.: :... .: :. .: : .:: .::
NP_000 MGHFTEEDKATITSLWGKVNVE--DAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGN
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 -QVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAH
.::.::::: .: .:. :.::. .... ::.:: ::.::: :::::.. :...:: :
NP_000 PKVKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIH
60 70 80 90 100 110
120 130 140
pF1KE1 LPAEFTPAVHASLDKFLASVSTVLTSKYR
. :::: :.:: .:....:...:.:.:
NP_000 FGKEFTPEVQASWQKMVTGVASALSSRYH
120 130 140
142 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:19:00 2016 done: Mon Nov 7 02:19:01 2016
Total Scan time: 4.770 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]