Result of FASTA (omim) for
pFN21AE1105
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1105, 94 aa
1>>>pF1KE1105 94 - 94 aa - 94 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8831+/-0.000266; mu= 11.4070+/- 0.017
mean_var=58.3622+/-11.350, 0's: 0 Z-trim(119.6): 8 B-trim: 0 in 0/51
Lambda= 0.167884
statistics sampled from 33911 (33919) to 33911 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.79), E-opt: 0.2 (0.398), width: 16
Scan time: 4.020
The best scores are: opt bits E(85289)
NP_005208 (OMIM: 604522) neutrophil defensin 3 pre ( 94) 647 163.8 3.6e-41
XP_011533043 (OMIM: 604522) PREDICTED: neutrophil ( 101) 647 163.9 3.8e-41
NP_004075 (OMIM: 125220) neutrophil defensin 1 pre ( 94) 637 161.4 1.9e-40
XP_011533042 (OMIM: 125220) PREDICTED: neutrophil ( 101) 637 161.4 2e-40
NP_001916 (OMIM: 601157) neutrophil defensin 4 pre ( 97) 276 74.0 4.1e-14
NP_066290 (OMIM: 600472) defensin-5 preproprotein ( 94) 269 72.3 1.3e-13
NP_001917 (OMIM: 600471) defensin-6 preproprotein ( 100) 250 67.7 3.3e-12
>>NP_005208 (OMIM: 604522) neutrophil defensin 3 preprop (94 aa)
initn: 647 init1: 647 opt: 647 Z-score: 860.1 bits: 163.8 E(85289): 3.6e-41
Smith-Waterman score: 647; 100.0% identity (100.0% similar) in 94 aa overlap (1-94:1-94)
10 20 30 40 50 60
pF1KE1 MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS
10 20 30 40 50 60
70 80 90
pF1KE1 RKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC
::::::::::::::::::::::::::::::::::
NP_005 RKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC
70 80 90
>>XP_011533043 (OMIM: 604522) PREDICTED: neutrophil defe (101 aa)
initn: 647 init1: 647 opt: 647 Z-score: 859.7 bits: 163.9 E(85289): 3.8e-41
Smith-Waterman score: 647; 100.0% identity (100.0% similar) in 94 aa overlap (1-94:8-101)
10 20 30 40 50
pF1KE1 MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRMVTPAMRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESL
10 20 30 40 50 60
60 70 80 90
pF1KE1 APKHPGSRKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC
:::::::::::::::::::::::::::::::::::::::::
XP_011 APKHPGSRKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC
70 80 90 100
>>NP_004075 (OMIM: 125220) neutrophil defensin 1 preprop (94 aa)
initn: 637 init1: 637 opt: 637 Z-score: 847.0 bits: 161.4 E(85289): 1.9e-40
Smith-Waterman score: 637; 98.9% identity (98.9% similar) in 94 aa overlap (1-94:1-94)
10 20 30 40 50 60
pF1KE1 MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS
10 20 30 40 50 60
70 80 90
pF1KE1 RKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC
:::: :::::::::::::::::::::::::::::
NP_004 RKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC
70 80 90
>>XP_011533042 (OMIM: 125220) PREDICTED: neutrophil defe (101 aa)
initn: 637 init1: 637 opt: 637 Z-score: 846.6 bits: 161.4 E(85289): 2e-40
Smith-Waterman score: 637; 98.9% identity (98.9% similar) in 94 aa overlap (1-94:8-101)
10 20 30 40 50
pF1KE1 MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRMVTPAMRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESL
10 20 30 40 50 60
60 70 80 90
pF1KE1 APKHPGSRKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC
::::::::::: :::::::::::::::::::::::::::::
XP_011 APKHPGSRKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC
70 80 90 100
>>NP_001916 (OMIM: 601157) neutrophil defensin 4 preprop (97 aa)
initn: 274 init1: 163 opt: 276 Z-score: 374.3 bits: 74.0 E(85289): 4.1e-14
Smith-Waterman score: 276; 46.8% identity (70.2% similar) in 94 aa overlap (1-94:1-93)
10 20 30 40 50 60
pF1KE1 MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS
:: .:.::::::::::..: :::::.:: : . :: . . .. .:.:::.: : . ::
NP_001 MRIIALLAAILLVALQVRAGPLQARGDE-APGQEQRGPEDQDISISFAWDKSSALQVSGS
10 20 30 40 50
70 80 90
pF1KE1 RKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC
..: : ::. : : : :.:. : ...::
NP_001 TRGMVCSCRLVFCRRTELRVGNCLIGGVSFTYCCTRVD
60 70 80 90
>>NP_066290 (OMIM: 600472) defensin-5 preproprotein [Hom (94 aa)
initn: 260 init1: 142 opt: 269 Z-score: 365.3 bits: 72.3 E(85289): 1.3e-13
Smith-Waterman score: 269; 48.9% identity (68.1% similar) in 94 aa overlap (1-94:1-93)
10 20 30 40 50 60
pF1KE1 MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS
:::.:::::::::::::::: :: :::: :.. .: . : ....:.: . : . ::
NP_066 MRTIAILAAILLVALQAQAESLQERADE-ATTQKQSGEDNQDLAISFAGNGLSALRTSGS
10 20 30 40 50
70 80 90
pF1KE1 RKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC
. :::: : . : :.: .:::. .::
NP_066 QARATCYCRTGRCATRESLSGVCEISGRLYRLCCR
60 70 80 90
>>NP_001917 (OMIM: 600471) defensin-6 preproprotein [Hom (100 aa)
initn: 284 init1: 130 opt: 250 Z-score: 340.1 bits: 67.7 E(85289): 3.3e-12
Smith-Waterman score: 250; 46.0% identity (65.0% similar) in 100 aa overlap (1-94:1-99)
10 20 30 40 50
pF1KE1 MRTLAILAAILLVALQAQAEPLQARADEVAA------APEQIAADIPEVVVSLAWDESLA
::::.::.:.:::::::.::::::. : . : : :: .:. . .::.: : : .
NP_001 MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSS
10 20 30 40 50 60
60 70 80 90
pF1KE1 PKHPGSRKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC
. :: . . :.:: .: . : :::: .: :::
NP_001 LRALGSTRAFTCHCR-RSCYSTEYSYGTCTVMGINHRFCCL
70 80 90 100
94 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:34:49 2016 done: Sun Nov 6 22:34:50 2016
Total Scan time: 4.020 Total Display time: -0.040
Function used was FASTA [36.3.4 Apr, 2011]