Result of FASTA (omim) for
pFN21AE0987
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0987, 616 aa
1>>>pF1KE0987 616 - 616 aa - 616 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.2839+/-0.00056; mu= -3.4622+/- 0.034
mean_var=709.2925+/-162.280, 0's: 0 Z-trim(117.7): 884 B-trim: 0 in 0/52
Lambda= 0.048157
statistics sampled from 28717 (29905) to 28717 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.698), E-opt: 0.2 (0.351), width: 16
Scan time: 9.590
The best scores are: opt bits E(85289)
NP_653286 (OMIM: 611712) homeodomain-interacting p ( 616) 4208 308.9 3.4e-83
XP_006723099 (OMIM: 611712) PREDICTED: homeodomain ( 619) 4192 307.8 7.3e-83
NP_001106710 (OMIM: 606868) homeodomain-interactin (1171) 1139 96.1 7.1e-19
XP_016867558 (OMIM: 606868) PREDICTED: homeodomain (1191) 1139 96.1 7.2e-19
XP_006715998 (OMIM: 606868) PREDICTED: homeodomain (1191) 1139 96.1 7.2e-19
NP_073577 (OMIM: 606868) homeodomain-interacting p (1198) 1139 96.1 7.2e-19
XP_011514383 (OMIM: 606868) PREDICTED: homeodomain (1206) 1139 96.2 7.2e-19
XP_011514382 (OMIM: 606868) PREDICTED: homeodomain (1349) 1139 96.2 7.6e-19
XP_011514381 (OMIM: 606868) PREDICTED: homeodomain (1350) 1139 96.2 7.6e-19
XP_011514380 (OMIM: 606868) PREDICTED: homeodomain (1376) 1139 96.2 7.7e-19
XP_011514379 (OMIM: 606868) PREDICTED: homeodomain (1377) 1139 96.2 7.7e-19
XP_016856095 (OMIM: 608003) PREDICTED: homeodomain ( 605) 1130 95.0 7.9e-19
NP_689909 (OMIM: 608003) homeodomain-interacting p (1075) 1134 95.7 8.6e-19
XP_016856094 (OMIM: 608003) PREDICTED: homeodomain (1209) 1134 95.8 9.2e-19
XP_005270669 (OMIM: 608003) PREDICTED: homeodomain (1210) 1134 95.8 9.2e-19
XP_005270670 (OMIM: 608003) PREDICTED: homeodomain (1210) 1134 95.8 9.2e-19
NP_938009 (OMIM: 608003) homeodomain-interacting p (1210) 1134 95.8 9.2e-19
XP_006710506 (OMIM: 608003) PREDICTED: homeodomain (1247) 1134 95.8 9.3e-19
XP_005270668 (OMIM: 608003) PREDICTED: homeodomain (1256) 1134 95.8 9.3e-19
XP_005270667 (OMIM: 608003) PREDICTED: homeodomain (1280) 1134 95.8 9.4e-19
XP_005270666 (OMIM: 608003) PREDICTED: homeodomain (1281) 1134 95.8 9.4e-19
NP_001265092 (OMIM: 604424) homeodomain-interactin (1194) 1095 93.1 6e-18
XP_016872566 (OMIM: 604424) PREDICTED: homeodomain (1194) 1095 93.1 6e-18
NP_001265091 (OMIM: 604424) homeodomain-interactin (1194) 1095 93.1 6e-18
NP_001041665 (OMIM: 604424) homeodomain-interactin (1194) 1095 93.1 6e-18
XP_005252786 (OMIM: 604424) PREDICTED: homeodomain (1215) 1095 93.1 6e-18
XP_016872565 (OMIM: 604424) PREDICTED: homeodomain (1215) 1095 93.1 6e-18
NP_005725 (OMIM: 604424) homeodomain-interacting p (1215) 1095 93.1 6e-18
XP_011539279 (OMIM: 608003) PREDICTED: homeodomain (1241) 841 75.5 1.2e-12
NP_569122 (OMIM: 600855,614104) dual specificity t ( 529) 645 61.2 1e-08
NP_567824 (OMIM: 600855,614104) dual specificity t ( 584) 645 61.3 1.1e-08
XP_011527787 (OMIM: 600855,614104) PREDICTED: dual ( 725) 645 61.5 1.2e-08
XP_016883775 (OMIM: 600855,614104) PREDICTED: dual ( 734) 645 61.5 1.2e-08
NP_569120 (OMIM: 600855,614104) dual specificity t ( 754) 645 61.5 1.2e-08
XP_006724042 (OMIM: 600855,614104) PREDICTED: dual ( 754) 645 61.5 1.2e-08
XP_016883773 (OMIM: 600855,614104) PREDICTED: dual ( 754) 645 61.5 1.2e-08
XP_016883774 (OMIM: 600855,614104) PREDICTED: dual ( 754) 645 61.5 1.2e-08
XP_011527786 (OMIM: 600855,614104) PREDICTED: dual ( 761) 645 61.5 1.2e-08
XP_006724040 (OMIM: 600855,614104) PREDICTED: dual ( 763) 645 61.5 1.2e-08
XP_006724041 (OMIM: 600855,614104) PREDICTED: dual ( 763) 645 61.5 1.2e-08
NP_001387 (OMIM: 600855,614104) dual specificity t ( 763) 645 61.5 1.2e-08
XP_006724039 (OMIM: 600855,614104) PREDICTED: dual ( 763) 645 61.5 1.2e-08
XP_011527785 (OMIM: 600855,614104) PREDICTED: dual ( 763) 645 61.5 1.2e-08
XP_011527784 (OMIM: 600855,614104) PREDICTED: dual ( 770) 645 61.5 1.2e-08
NP_003836 (OMIM: 609181) dual specificity tyrosine ( 520) 622 59.6 3.1e-08
NP_006474 (OMIM: 604556,615812) dual specificity t ( 589) 620 59.6 3.6e-08
NP_006475 (OMIM: 604556,615812) dual specificity t ( 601) 613 59.1 5.1e-08
NP_004705 (OMIM: 604556,615812) dual specificity t ( 629) 613 59.1 5.2e-08
XP_005259455 (OMIM: 604556,615812) PREDICTED: dual ( 629) 613 59.1 5.2e-08
NP_003574 (OMIM: 603496) dual specificity tyrosine ( 528) 588 57.3 1.6e-07
>>NP_653286 (OMIM: 611712) homeodomain-interacting prote (616 aa)
initn: 4208 init1: 4208 opt: 4208 Z-score: 1614.7 bits: 308.9 E(85289): 3.4e-83
Smith-Waterman score: 4208; 100.0% identity (100.0% similar) in 616 aa overlap (1-616:1-616)
10 20 30 40 50 60
pF1KE0 MSTIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRNRIIKNELKLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 MSTIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRNRIIKNELKLLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 CMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 CMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LTALARLKELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 LTALARLKELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 YRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 YRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 AACKAHHFFKRNPHPDAANPWQLKSSADYLAETKVRPLERRKYMLKSLDQIETVNGGSVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 AACKAHHFFKRNPHPDAANPWQLKSSADYLAETKVRPLERRKYMLKSLDQIETVNGGSVA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SRLTFPDREALAEHADLKSMVELIKRMLTWESHERISPSAALRHPFVSMQQLRSAHETTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 SRLTFPDREALAEHADLKSMVELIKRMLTWESHERISPSAALRHPFVSMQQLRSAHETTH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 YYQLSLRSYRLSLQVEGKPPTPVVAAEDGTPYYCLAEEKEAAGMGSVAGSSPFFREEKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 YYQLSLRSYRLSLQVEGKPPTPVVAAEDGTPYYCLAEEKEAAGMGSVAGSSPFFREEKAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 GMQRAIDQLDDLSLQEAGHGLWGETCTNAVSDMMVPLKAAITGHHVPDSGPEPILAFYSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 GMQRAIDQLDDLSLQEAGHGLWGETCTNAVSDMMVPLKAAITGHHVPDSGPEPILAFYSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 RLAGRHKARKPPAGSKSDSNFSNLIRLSQVSPEDDRPCRGSSWEEGEHLGASAEPLAILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 RLAGRHKARKPPAGSKSDSNFSNLIRLSQVSPEDDRPCRGSSWEEGEHLGASAEPLAILQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 RDEDGPNIDNMTMEAERPDPELFDPSSCPGEWLSEPDCTLESVRGPRAQGLPPRRSHQHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 RDEDGPNIDNMTMEAERPDPELFDPSSCPGEWLSEPDCTLESVRGPRAQGLPPRRSHQHG
550 560 570 580 590 600
610
pF1KE0 PPRGATSFLQHVTGHH
::::::::::::::::
NP_653 PPRGATSFLQHVTGHH
610
>>XP_006723099 (OMIM: 611712) PREDICTED: homeodomain-int (619 aa)
initn: 3752 init1: 3752 opt: 4192 Z-score: 1608.7 bits: 307.8 E(85289): 7.3e-83
Smith-Waterman score: 4192; 99.5% identity (99.5% similar) in 619 aa overlap (1-616:1-619)
10 20 30 40 50 60
pF1KE0 MSTIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRNRIIKNELKLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSTIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRNRIIKNELKLLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 CMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LTALARLKELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTALARLKELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 YRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 AACKAHHFFKRNPHPDAANPWQLKSSADYLAETKVRPLERRKYMLKSLDQIETVNGGSVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AACKAHHFFKRNPHPDAANPWQLKSSADYLAETKVRPLERRKYMLKSLDQIETVNGGSVA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SRLTFPDREALAEHADLKSMVELIKRMLTWESHERISPSAALRHPFVSMQQLRSAHETTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SRLTFPDREALAEHADLKSMVELIKRMLTWESHERISPSAALRHPFVSMQQLRSAHETTH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 YYQLSLRSYRLSLQVEGKPPTPVVAAEDGTPYYCLAEEKEAAGMGSVAGSSPFFREEKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YYQLSLRSYRLSLQVEGKPPTPVVAAEDGTPYYCLAEEKEAAGMGSVAGSSPFFREEKAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 GMQRAIDQLDDLSLQEAGHGLWGETCTNAVSDMMVPLKAAITGHHVPDSGPEPILAFYSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GMQRAIDQLDDLSLQEAGHGLWGETCTNAVSDMMVPLKAAITGHHVPDSGPEPILAFYSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 RLAGRHKARKPPAGSKSDSNFSNLIRLSQVSPEDDRPCRGSSWEEGEHLGASAEPLAILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLAGRHKARKPPAGSKSDSNFSNLIRLSQVSPEDDRPCRGSSWEEGEHLGASAEPLAILQ
490 500 510 520 530 540
550 560 570 580 590
pF1KE0 RDEDGPNIDNMTMEAE---RPDPELFDPSSCPGEWLSEPDCTLESVRGPRAQGLPPRRSH
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_006 RDEDGPNIDNMTMEAEVSRRPDPELFDPSSCPGEWLSEPDCTLESVRGPRAQGLPPRRSH
550 560 570 580 590 600
600 610
pF1KE0 QHGPPRGATSFLQHVTGHH
:::::::::::::::::::
XP_006 QHGPPRGATSFLQHVTGHH
610
>>NP_001106710 (OMIM: 606868) homeodomain-interacting pr (1171 aa)
initn: 1146 init1: 532 opt: 1139 Z-score: 459.9 bits: 96.1 E(85289): 7.1e-19
Smith-Waterman score: 1139; 50.6% identity (74.4% similar) in 356 aa overlap (6-360:194-540)
10 20 30
pF1KE0 MSTIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGE
: :. :...: ::.::::.:.: :.:.:.:
NP_001 ATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNE
170 180 190 200 210 220
40 50 60 70 80 90
pF1KE0 MVAIKILKNDAYRNRIIKNELKLLHCMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQN
.:::::::: : . :...: . . .. . .: : :. . ::::.::::
NP_001 IVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQN
230 240 250 260 270 280
100 110 120 130 140 150
pF1KE0 LFEFQKENNFAPLPARHIRTVTLQVLTALARLKELAIIHADLKPENIMLVDQTRCPFRVK
:..: :.:.:.::: ..:: : :: ::: .:: :..:::::::::::::: .: :.:::
NP_001 LYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVK
290 300 310 320 330 340
160 170 180 190 200 210
pF1KE0 VIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLY
:::::::: :.. : :.:::.::::::.::::::: .:.::::::.::: ::::::
NP_001 VIDFGSASHVSKA--VCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLY
350 360 370 380 390 400
220 230 240 250 260 270
pF1KE0 PGNNEYDQVRYICETQGLPKPHLLHAACKAHHFFKRNPHPDAANP-WQLKSSADYLAETK
:: .::::.::: .::::: .:: :. :. .::.:. :. : :.::. :. :::
NP_001 PGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDT--DSPYPLWRLKTPDDHEAETG
410 420 430 440 450
280 290 300 310 320 330
pF1KE0 VRPLERRKYMLKSLDQIETVNGGSVASRLTFPDREALAEHADLKSMVELIKRMLTWESHE
.. : :::... ::.. :: ... : : :.:.:: . ...:.:.::: .. .
NP_001 IKSKEARKYIFNCLDDMAQVN---MTTDLEGSD--MLVEKADRREFIDLLKKMLTIDADK
460 470 480 490 500 510
340 350 360 370 380 390
pF1KE0 RISPSAALRHPFVSMQQLRSAHETTHYYQLSLRSYRLSLQVEGKPPTPVVAAEDGTPYYC
::.: .: ::::.: .: . ..::
NP_001 RITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAP
520 530 540 550 560 570
>>XP_016867558 (OMIM: 606868) PREDICTED: homeodomain-int (1191 aa)
initn: 1146 init1: 532 opt: 1139 Z-score: 459.8 bits: 96.1 E(85289): 7.2e-19
Smith-Waterman score: 1139; 50.6% identity (74.4% similar) in 356 aa overlap (6-360:187-533)
10 20 30
pF1KE0 MSTIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGE
: :. :...: ::.::::.:.: :.:.:.:
XP_016 ATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNE
160 170 180 190 200 210
40 50 60 70 80 90
pF1KE0 MVAIKILKNDAYRNRIIKNELKLLHCMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQN
.:::::::: : . :...: . . .. . .: : :. . ::::.::::
XP_016 IVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQN
220 230 240 250 260 270
100 110 120 130 140 150
pF1KE0 LFEFQKENNFAPLPARHIRTVTLQVLTALARLKELAIIHADLKPENIMLVDQTRCPFRVK
:..: :.:.:.::: ..:: : :: ::: .:: :..:::::::::::::: .: :.:::
XP_016 LYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVK
280 290 300 310 320 330
160 170 180 190 200 210
pF1KE0 VIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLY
:::::::: :.. : :.:::.::::::.::::::: .:.::::::.::: ::::::
XP_016 VIDFGSASHVSKA--VCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLY
340 350 360 370 380 390
220 230 240 250 260 270
pF1KE0 PGNNEYDQVRYICETQGLPKPHLLHAACKAHHFFKRNPHPDAANP-WQLKSSADYLAETK
:: .::::.::: .::::: .:: :. :. .::.:. :. : :.::. :. :::
XP_016 PGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDT--DSPYPLWRLKTPDDHEAETG
400 410 420 430 440 450
280 290 300 310 320 330
pF1KE0 VRPLERRKYMLKSLDQIETVNGGSVASRLTFPDREALAEHADLKSMVELIKRMLTWESHE
.. : :::... ::.. :: ... : : :.:.:: . ...:.:.::: .. .
XP_016 IKSKEARKYIFNCLDDMAQVN---MTTDLEGSD--MLVEKADRREFIDLLKKMLTIDADK
460 470 480 490 500
340 350 360 370 380 390
pF1KE0 RISPSAALRHPFVSMQQLRSAHETTHYYQLSLRSYRLSLQVEGKPPTPVVAAEDGTPYYC
::.: .: ::::.: .: . ..::
XP_016 RITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAP
510 520 530 540 550 560
>>XP_006715998 (OMIM: 606868) PREDICTED: homeodomain-int (1191 aa)
initn: 1146 init1: 532 opt: 1139 Z-score: 459.8 bits: 96.1 E(85289): 7.2e-19
Smith-Waterman score: 1139; 50.6% identity (74.4% similar) in 356 aa overlap (6-360:187-533)
10 20 30
pF1KE0 MSTIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGE
: :. :...: ::.::::.:.: :.:.:.:
XP_006 ATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNE
160 170 180 190 200 210
40 50 60 70 80 90
pF1KE0 MVAIKILKNDAYRNRIIKNELKLLHCMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQN
.:::::::: : . :...: . . .. . .: : :. . ::::.::::
XP_006 IVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQN
220 230 240 250 260 270
100 110 120 130 140 150
pF1KE0 LFEFQKENNFAPLPARHIRTVTLQVLTALARLKELAIIHADLKPENIMLVDQTRCPFRVK
:..: :.:.:.::: ..:: : :: ::: .:: :..:::::::::::::: .: :.:::
XP_006 LYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVK
280 290 300 310 320 330
160 170 180 190 200 210
pF1KE0 VIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLY
:::::::: :.. : :.:::.::::::.::::::: .:.::::::.::: ::::::
XP_006 VIDFGSASHVSKA--VCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLY
340 350 360 370 380 390
220 230 240 250 260 270
pF1KE0 PGNNEYDQVRYICETQGLPKPHLLHAACKAHHFFKRNPHPDAANP-WQLKSSADYLAETK
:: .::::.::: .::::: .:: :. :. .::.:. :. : :.::. :. :::
XP_006 PGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDT--DSPYPLWRLKTPDDHEAETG
400 410 420 430 440 450
280 290 300 310 320 330
pF1KE0 VRPLERRKYMLKSLDQIETVNGGSVASRLTFPDREALAEHADLKSMVELIKRMLTWESHE
.. : :::... ::.. :: ... : : :.:.:: . ...:.:.::: .. .
XP_006 IKSKEARKYIFNCLDDMAQVN---MTTDLEGSD--MLVEKADRREFIDLLKKMLTIDADK
460 470 480 490 500
340 350 360 370 380 390
pF1KE0 RISPSAALRHPFVSMQQLRSAHETTHYYQLSLRSYRLSLQVEGKPPTPVVAAEDGTPYYC
::.: .: ::::.: .: . ..::
XP_006 RITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAP
510 520 530 540 550 560
>>NP_073577 (OMIM: 606868) homeodomain-interacting prote (1198 aa)
initn: 1146 init1: 532 opt: 1139 Z-score: 459.8 bits: 96.1 E(85289): 7.2e-19
Smith-Waterman score: 1139; 50.6% identity (74.4% similar) in 356 aa overlap (6-360:194-540)
10 20 30
pF1KE0 MSTIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGE
: :. :...: ::.::::.:.: :.:.:.:
NP_073 ATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNE
170 180 190 200 210 220
40 50 60 70 80 90
pF1KE0 MVAIKILKNDAYRNRIIKNELKLLHCMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQN
.:::::::: : . :...: . . .. . .: : :. . ::::.::::
NP_073 IVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQN
230 240 250 260 270 280
100 110 120 130 140 150
pF1KE0 LFEFQKENNFAPLPARHIRTVTLQVLTALARLKELAIIHADLKPENIMLVDQTRCPFRVK
:..: :.:.:.::: ..:: : :: ::: .:: :..:::::::::::::: .: :.:::
NP_073 LYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVK
290 300 310 320 330 340
160 170 180 190 200 210
pF1KE0 VIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLY
:::::::: :.. : :.:::.::::::.::::::: .:.::::::.::: ::::::
NP_073 VIDFGSASHVSKA--VCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLY
350 360 370 380 390 400
220 230 240 250 260 270
pF1KE0 PGNNEYDQVRYICETQGLPKPHLLHAACKAHHFFKRNPHPDAANP-WQLKSSADYLAETK
:: .::::.::: .::::: .:: :. :. .::.:. :. : :.::. :. :::
NP_073 PGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDT--DSPYPLWRLKTPDDHEAETG
410 420 430 440 450
280 290 300 310 320 330
pF1KE0 VRPLERRKYMLKSLDQIETVNGGSVASRLTFPDREALAEHADLKSMVELIKRMLTWESHE
.. : :::... ::.. :: ... : : :.:.:: . ...:.:.::: .. .
NP_073 IKSKEARKYIFNCLDDMAQVN---MTTDLEGSD--MLVEKADRREFIDLLKKMLTIDADK
460 470 480 490 500 510
340 350 360 370 380 390
pF1KE0 RISPSAALRHPFVSMQQLRSAHETTHYYQLSLRSYRLSLQVEGKPPTPVVAAEDGTPYYC
::.: .: ::::.: .: . ..::
NP_073 RITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAP
520 530 540 550 560 570
>>XP_011514383 (OMIM: 606868) PREDICTED: homeodomain-int (1206 aa)
initn: 1146 init1: 532 opt: 1139 Z-score: 459.7 bits: 96.2 E(85289): 7.2e-19
Smith-Waterman score: 1139; 50.6% identity (74.4% similar) in 356 aa overlap (6-360:202-548)
10 20 30
pF1KE0 MSTIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGE
: :. :...: ::.::::.:.: :.:.:.:
XP_011 ATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNE
180 190 200 210 220 230
40 50 60 70 80 90
pF1KE0 MVAIKILKNDAYRNRIIKNELKLLHCMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQN
.:::::::: : . :...: . . .. . .: : :. . ::::.::::
XP_011 IVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQN
240 250 260 270 280 290
100 110 120 130 140 150
pF1KE0 LFEFQKENNFAPLPARHIRTVTLQVLTALARLKELAIIHADLKPENIMLVDQTRCPFRVK
:..: :.:.:.::: ..:: : :: ::: .:: :..:::::::::::::: .: :.:::
XP_011 LYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVK
300 310 320 330 340 350
160 170 180 190 200 210
pF1KE0 VIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLY
:::::::: :.. : :.:::.::::::.::::::: .:.::::::.::: ::::::
XP_011 VIDFGSASHVSKA--VCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLY
360 370 380 390 400
220 230 240 250 260 270
pF1KE0 PGNNEYDQVRYICETQGLPKPHLLHAACKAHHFFKRNPHPDAANP-WQLKSSADYLAETK
:: .::::.::: .::::: .:: :. :. .::.:. :. : :.::. :. :::
XP_011 PGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDT--DSPYPLWRLKTPDDHEAETG
410 420 430 440 450 460
280 290 300 310 320 330
pF1KE0 VRPLERRKYMLKSLDQIETVNGGSVASRLTFPDREALAEHADLKSMVELIKRMLTWESHE
.. : :::... ::.. :: ... : : :.:.:: . ...:.:.::: .. .
XP_011 IKSKEARKYIFNCLDDMAQVN---MTTDLEGSD--MLVEKADRREFIDLLKKMLTIDADK
470 480 490 500 510 520
340 350 360 370 380 390
pF1KE0 RISPSAALRHPFVSMQQLRSAHETTHYYQLSLRSYRLSLQVEGKPPTPVVAAEDGTPYYC
::.: .: ::::.: .: . ..::
XP_011 RITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAP
530 540 550 560 570 580
>>XP_011514382 (OMIM: 606868) PREDICTED: homeodomain-int (1349 aa)
initn: 1146 init1: 532 opt: 1139 Z-score: 459.3 bits: 96.2 E(85289): 7.6e-19
Smith-Waterman score: 1139; 50.6% identity (74.4% similar) in 356 aa overlap (6-360:373-719)
10 20 30
pF1KE0 MSTIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGE
: :. :...: ::.::::.:.: :.:.:.:
XP_011 ATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNE
350 360 370 380 390 400
40 50 60 70 80 90
pF1KE0 MVAIKILKNDAYRNRIIKNELKLLHCMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQN
.:::::::: : . :...: . . .. . .: : :. . ::::.::::
XP_011 IVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQN
410 420 430 440 450 460
100 110 120 130 140 150
pF1KE0 LFEFQKENNFAPLPARHIRTVTLQVLTALARLKELAIIHADLKPENIMLVDQTRCPFRVK
:..: :.:.:.::: ..:: : :: ::: .:: :..:::::::::::::: .: :.:::
XP_011 LYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVK
470 480 490 500 510 520
160 170 180 190 200 210
pF1KE0 VIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLY
:::::::: :.. : :.:::.::::::.::::::: .:.::::::.::: ::::::
XP_011 VIDFGSASHVSKA--VCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLY
530 540 550 560 570 580
220 230 240 250 260 270
pF1KE0 PGNNEYDQVRYICETQGLPKPHLLHAACKAHHFFKRNPHPDAANP-WQLKSSADYLAETK
:: .::::.::: .::::: .:: :. :. .::.:. :. : :.::. :. :::
XP_011 PGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDT--DSPYPLWRLKTPDDHEAETG
590 600 610 620 630
280 290 300 310 320 330
pF1KE0 VRPLERRKYMLKSLDQIETVNGGSVASRLTFPDREALAEHADLKSMVELIKRMLTWESHE
.. : :::... ::.. :: ... : : :.:.:: . ...:.:.::: .. .
XP_011 IKSKEARKYIFNCLDDMAQVN---MTTDLEGSD--MLVEKADRREFIDLLKKMLTIDADK
640 650 660 670 680 690
340 350 360 370 380 390
pF1KE0 RISPSAALRHPFVSMQQLRSAHETTHYYQLSLRSYRLSLQVEGKPPTPVVAAEDGTPYYC
::.: .: ::::.: .: . ..::
XP_011 RITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAP
700 710 720 730 740 750
>>XP_011514381 (OMIM: 606868) PREDICTED: homeodomain-int (1350 aa)
initn: 1146 init1: 532 opt: 1139 Z-score: 459.3 bits: 96.2 E(85289): 7.6e-19
Smith-Waterman score: 1139; 50.6% identity (74.4% similar) in 356 aa overlap (6-360:373-719)
10 20 30
pF1KE0 MSTIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGE
: :. :...: ::.::::.:.: :.:.:.:
XP_011 ATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNE
350 360 370 380 390 400
40 50 60 70 80 90
pF1KE0 MVAIKILKNDAYRNRIIKNELKLLHCMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQN
.:::::::: : . :...: . . .. . .: : :. . ::::.::::
XP_011 IVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQN
410 420 430 440 450 460
100 110 120 130 140 150
pF1KE0 LFEFQKENNFAPLPARHIRTVTLQVLTALARLKELAIIHADLKPENIMLVDQTRCPFRVK
:..: :.:.:.::: ..:: : :: ::: .:: :..:::::::::::::: .: :.:::
XP_011 LYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVK
470 480 490 500 510 520
160 170 180 190 200 210
pF1KE0 VIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLY
:::::::: :.. : :.:::.::::::.::::::: .:.::::::.::: ::::::
XP_011 VIDFGSASHVSKA--VCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLY
530 540 550 560 570 580
220 230 240 250 260 270
pF1KE0 PGNNEYDQVRYICETQGLPKPHLLHAACKAHHFFKRNPHPDAANP-WQLKSSADYLAETK
:: .::::.::: .::::: .:: :. :. .::.:. :. : :.::. :. :::
XP_011 PGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDT--DSPYPLWRLKTPDDHEAETG
590 600 610 620 630
280 290 300 310 320 330
pF1KE0 VRPLERRKYMLKSLDQIETVNGGSVASRLTFPDREALAEHADLKSMVELIKRMLTWESHE
.. : :::... ::.. :: ... : : :.:.:: . ...:.:.::: .. .
XP_011 IKSKEARKYIFNCLDDMAQVN---MTTDLEGSD--MLVEKADRREFIDLLKKMLTIDADK
640 650 660 670 680 690
340 350 360 370 380 390
pF1KE0 RISPSAALRHPFVSMQQLRSAHETTHYYQLSLRSYRLSLQVEGKPPTPVVAAEDGTPYYC
::.: .: ::::.: .: . ..::
XP_011 RITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAP
700 710 720 730 740 750
>>XP_011514380 (OMIM: 606868) PREDICTED: homeodomain-int (1376 aa)
initn: 1146 init1: 532 opt: 1139 Z-score: 459.2 bits: 96.2 E(85289): 7.7e-19
Smith-Waterman score: 1139; 50.6% identity (74.4% similar) in 356 aa overlap (6-360:373-719)
10 20 30
pF1KE0 MSTIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGE
: :. :...: ::.::::.:.: :.:.:.:
XP_011 ATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNE
350 360 370 380 390 400
40 50 60 70 80 90
pF1KE0 MVAIKILKNDAYRNRIIKNELKLLHCMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQN
.:::::::: : . :...: . . .. . .: : :. . ::::.::::
XP_011 IVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQN
410 420 430 440 450 460
100 110 120 130 140 150
pF1KE0 LFEFQKENNFAPLPARHIRTVTLQVLTALARLKELAIIHADLKPENIMLVDQTRCPFRVK
:..: :.:.:.::: ..:: : :: ::: .:: :..:::::::::::::: .: :.:::
XP_011 LYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVK
470 480 490 500 510 520
160 170 180 190 200 210
pF1KE0 VIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLY
:::::::: :.. : :.:::.::::::.::::::: .:.::::::.::: ::::::
XP_011 VIDFGSASHVSKA--VCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLY
530 540 550 560 570 580
220 230 240 250 260 270
pF1KE0 PGNNEYDQVRYICETQGLPKPHLLHAACKAHHFFKRNPHPDAANP-WQLKSSADYLAETK
:: .::::.::: .::::: .:: :. :. .::.:. :. : :.::. :. :::
XP_011 PGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDT--DSPYPLWRLKTPDDHEAETG
590 600 610 620 630
280 290 300 310 320 330
pF1KE0 VRPLERRKYMLKSLDQIETVNGGSVASRLTFPDREALAEHADLKSMVELIKRMLTWESHE
.. : :::... ::.. :: ... : : :.:.:: . ...:.:.::: .. .
XP_011 IKSKEARKYIFNCLDDMAQVN---MTTDLEGSD--MLVEKADRREFIDLLKKMLTIDADK
640 650 660 670 680 690
340 350 360 370 380 390
pF1KE0 RISPSAALRHPFVSMQQLRSAHETTHYYQLSLRSYRLSLQVEGKPPTPVVAAEDGTPYYC
::.: .: ::::.: .: . ..::
XP_011 RITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAP
700 710 720 730 740 750
616 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:36:31 2016 done: Mon Nov 7 16:36:33 2016
Total Scan time: 9.590 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]