FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0955, 483 aa
  1>>>pF1KE0955 483 - 483 aa - 483 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 12.8106+/-0.00136; mu= -15.8727+/- 0.080
 mean_var=600.4944+/-129.714, 0's: 0 Z-trim(114.0): 418  B-trim: 0 in 0/51
 Lambda= 0.052338
 statistics sampled from 14119 (14575) to 14119 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.753), E-opt: 0.2 (0.448), width:  16
 Scan time:  3.110

The best scores are:                                      opt bits E(32554)
CCDS12599.1 GSK3A gene_id:2931|Hs108|chr19         ( 483) 3250 260.4   3e-69
CCDS54628.1 GSK3B gene_id:2932|Hs108|chr3          ( 420) 2082 172.2 9.7e-43
CCDS2996.1 GSK3B gene_id:2932|Hs108|chr3           ( 433) 1676 141.5 1.7e-33


>>CCDS12599.1 GSK3A gene_id:2931|Hs108|chr19              (483 aa)
 initn: 3250 init1: 3250 opt: 3250  Z-score: 1356.7  bits: 260.4 E(32554): 3e-69
Smith-Waterman score: 3250; 100.0% identity (100.0% similar) in 483 aa overlap (1-483:1-483)

               10        20        30        40        50        60
pF1KE0 MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 GASSSGGGPGGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATLGQGPERSQEVAYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 GASSSGGGPGGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATLGQGPERSQEVAYT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 DIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 DIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 SSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 SSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 CHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 CHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 IDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 IDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 AHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRCLGTQLPNNRPLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 AHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRCLGTQLPNNRPLP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 PLFNFSAGELSIQPSLNAILIPPHLRSPAGTTTLTPSSQALTETPTSSDWQSTDATPTLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 PLFNFSAGELSIQPSLNAILIPPHLRSPAGTTTLTPSSQALTETPTSSDWQSTDATPTLT
              430       440       450       460       470       480

          
pF1KE0 NSS
       :::
CCDS12 NSS
          

>>CCDS54628.1 GSK3B gene_id:2932|Hs108|chr3               (420 aa)
 initn: 2131 init1: 2065 opt: 2082  Z-score: 880.8  bits: 172.2 E(32554): 9.7e-43
Smith-Waterman score: 2082; 78.1% identity (90.8% similar) in 401 aa overlap (84-483:21-420)

            60        70        80        90       100       110   
pF1KE0 GAMGGGVGASSSGGGPGGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATLGQGPER
                                     ..:    :.  .:..:::::::: ::::.:
CCDS54           MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDR
                         10        20        30        40        50

           120       130       140       150       160       170   
pF1KE0 SQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIV
        :::.::: ::::::::::::::.: .. :::::::::::::::::::::::::::::::
CCDS54 PQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIV
               60        70        80        90       100       110

           180       190       200       210       220       230   
pF1KE0 RLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLA
       :::::::::::::::.::::::.::::::::::::...:: :.:..:::.::::::::::
CCDS54 RLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLA
              120       130       140       150       160       170

           240       250       260       270       280       290   
pF1KE0 YIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFG
       :::: :.:::::::::::.:::::::::::::::::::::::::::::::::::::::::
CCDS54 YIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFG
              180       190       200       210       220       230

           300       310       320       330       340       350   
pF1KE0 ATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTE
              240       250       260       270       280       290

           360       370       380       390       400       410   
pF1KE0 FKFPQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRCLGTQL
       :::::::::::::::. ::::::::::: ::::::..::.::::::::::::::  ...:
CCDS54 FKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKL
              300       310       320       330       340       350

           420       430       440       450       460       470   
pF1KE0 PNNRPLPPLFNFSAGELSIQPSLNAILIPPHLRSPAGTTTLTPSSQALTETPTSSDWQST
       ::.:  : ::::.. ::: .: : .:::::: :  :...: : .. : ... :..  :..
CCDS54 PNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAA-SDANTGDRGQTN
              360       370       380       390        400         

            480   
pF1KE0 DA-TPTLTNSS
       .: . . .::.
CCDS54 NAASASASNST
     410       420

>>CCDS2996.1 GSK3B gene_id:2932|Hs108|chr3                (433 aa)
 initn: 2106 init1: 1673 opt: 1676  Z-score: 714.9  bits: 141.5 E(32554): 1.7e-33
Smith-Waterman score: 2046; 75.6% identity (87.9% similar) in 414 aa overlap (84-483:21-433)

            60        70        80        90       100       110   
pF1KE0 GAMGGGVGASSSGGGPGGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATLGQGPER
                                     ..:    :.  .:..:::::::: ::::.:
CCDS29           MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDR
                         10        20        30        40        50

           120       130       140       150       160       170   
pF1KE0 SQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIV
        :::.::: ::::::::::::::.: .. :::::::::::::::::::::::::::::::
CCDS29 PQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIV
               60        70        80        90       100       110

           180       190       200       210       220       230   
pF1KE0 RLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLA
       :::::::::::::::.::::::.::::::::::::...:: :.:..:::.::::::::::
CCDS29 RLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLA
              120       130       140       150       160       170

           240       250       260       270       280       290   
pF1KE0 YIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFG
       :::: :.:::::::::::.:::::::::::::::::::::::::::::::::::::::::
CCDS29 YIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFG
              180       190       200       210       220       230

           300       310       320       330       340       350   
pF1KE0 ATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 ATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTE
              240       250       260       270       280       290

           360                    370       380       390       400
pF1KE0 FKFPQIKAHPWTK-------------VFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAH
       :::::::::::::             ::. ::::::::::: ::::::..::.:::::::
CCDS29 FKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAH
              300       310       320       330       340       350

              410       420       430       440       450       460
pF1KE0 SFFDELRCLGTQLPNNRPLPPLFNFSAGELSIQPSLNAILIPPHLRSPAGTTTLTPSSQA
       :::::::  ...:::.:  : ::::.. ::: .: : .:::::: :  :...: : .. :
CCDS29 SFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAA
              360       370       380       390       400       410

              470        480   
pF1KE0 LTETPTSSDWQSTDA-TPTLTNSS
        ... :..  :...: . . .::.
CCDS29 -SDANTGDRGQTNNAASASASNST
               420       430   




483 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 06:09:28 2016 done: Sun Nov  6 06:09:28 2016
 Total Scan time:  3.110 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]