Result of FASTA (omim) for
pFN21AE0899
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0899, 1246 aa
1>>>pF1KE0899 1246 - 1246 aa - 1246 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2582+/-0.000404; mu= 9.9686+/- 0.025
mean_var=189.5801+/-38.386, 0's: 0 Z-trim(118.4): 91 B-trim: 726 in 1/53
Lambda= 0.093149
statistics sampled from 31272 (31368) to 31272 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.698), E-opt: 0.2 (0.368), width: 16
Scan time: 17.630
The best scores are: opt bits E(85289)
NP_004964 (OMIM: 601594) protein Jumonji isoform 1 (1246) 8374 1138.9 0
XP_016866322 (OMIM: 601594) PREDICTED: protein Jum (1294) 8276 1125.8 0
XP_011512881 (OMIM: 601594) PREDICTED: protein Jum (1309) 7305 995.3 0
XP_016866323 (OMIM: 601594) PREDICTED: protein Jum (1074) 7247 987.4 0
XP_005249146 (OMIM: 601594) PREDICTED: protein Jum (1074) 7247 987.4 0
NP_001253969 (OMIM: 601594) protein Jumonji isofor (1074) 7247 987.4 0
XP_016866324 (OMIM: 601594) PREDICTED: protein Jum (1074) 7247 987.4 0
XP_011512886 (OMIM: 601594) PREDICTED: protein Jum ( 826) 5262 720.6 1.1e-206
XP_011529133 (OMIM: 300534,314690) PREDICTED: lysi (1232) 417 69.6 1.4e-10
NP_001140174 (OMIM: 300534,314690) lysine-specific (1379) 417 69.7 1.6e-10
XP_011529131 (OMIM: 300534,314690) PREDICTED: lysi (1395) 417 69.7 1.6e-10
XP_011529132 (OMIM: 300534,314690) PREDICTED: lysi (1395) 417 69.7 1.6e-10
XP_016885378 (OMIM: 300534,314690) PREDICTED: lysi (1444) 417 69.7 1.6e-10
XP_011529130 (OMIM: 300534,314690) PREDICTED: lysi (1447) 417 69.7 1.6e-10
XP_016885377 (OMIM: 300534,314690) PREDICTED: lysi (1448) 417 69.7 1.6e-10
XP_016885376 (OMIM: 300534,314690) PREDICTED: lysi (1449) 417 69.7 1.6e-10
XP_016885375 (OMIM: 300534,314690) PREDICTED: lysi (1451) 417 69.7 1.6e-10
XP_011529129 (OMIM: 300534,314690) PREDICTED: lysi (1452) 417 69.7 1.6e-10
XP_011529128 (OMIM: 300534,314690) PREDICTED: lysi (1516) 417 69.7 1.7e-10
XP_011529127 (OMIM: 300534,314690) PREDICTED: lysi (1519) 417 69.7 1.7e-10
XP_011529126 (OMIM: 300534,314690) PREDICTED: lysi (1534) 417 69.7 1.7e-10
XP_005262092 (OMIM: 300534,314690) PREDICTED: lysi (1557) 417 69.7 1.7e-10
NP_001269551 (OMIM: 300534,314690) lysine-specific (1559) 417 69.7 1.7e-10
NP_004178 (OMIM: 300534,314690) lysine-specific de (1560) 417 69.7 1.7e-10
NP_001140177 (OMIM: 415000,426000) lysine-specific (1570) 404 68.0 5.8e-10
XP_005262618 (OMIM: 415000,426000) PREDICTED: lysi (1462) 403 67.8 6e-10
NP_001140178 (OMIM: 415000,426000) lysine-specific (1482) 403 67.8 6.1e-10
XP_005262617 (OMIM: 415000,426000) PREDICTED: lysi (1494) 403 67.8 6.1e-10
XP_011529770 (OMIM: 415000,426000) PREDICTED: lysi (1513) 403 67.8 6.2e-10
NP_004644 (OMIM: 415000,426000) lysine-specific de (1539) 403 67.8 6.3e-10
XP_011507394 (OMIM: 605393) PREDICTED: lysine-spec (1386) 367 62.9 1.7e-08
XP_011507392 (OMIM: 605393) PREDICTED: lysine-spec (1422) 367 63.0 1.7e-08
XP_011507393 (OMIM: 605393) PREDICTED: lysine-spec (1422) 367 63.0 1.7e-08
NP_060509 (OMIM: 609766) lysine-specific demethyla ( 523) 301 53.8 3.7e-06
XP_011526120 (OMIM: 609765) PREDICTED: lysine-spec ( 429) 298 53.3 4.2e-06
XP_016881993 (OMIM: 609765) PREDICTED: lysine-spec ( 473) 294 52.8 6.5e-06
XP_011526116 (OMIM: 609765) PREDICTED: lysine-spec (1038) 294 53.0 1.2e-05
NP_055830 (OMIM: 609765) lysine-specific demethyla (1096) 294 53.1 1.2e-05
XP_016881992 (OMIM: 609765) PREDICTED: lysine-spec (1130) 294 53.1 1.3e-05
XP_005259578 (OMIM: 609765) PREDICTED: lysine-spec (1130) 294 53.1 1.3e-05
NP_006609 (OMIM: 605393) lysine-specific demethyla (1544) 293 53.0 1.8e-05
NP_001155102 (OMIM: 616581) lysine-specific demeth ( 506) 281 51.1 2.3e-05
XP_011526124 (OMIM: 609765) PREDICTED: lysine-spec ( 312) 275 50.1 2.8e-05
XP_011526123 (OMIM: 609765) PREDICTED: lysine-spec ( 330) 275 50.1 2.9e-05
XP_016881994 (OMIM: 609765) PREDICTED: lysine-spec ( 330) 275 50.1 2.9e-05
XP_011526122 (OMIM: 609765) PREDICTED: lysine-spec ( 330) 275 50.1 2.9e-05
XP_011526121 (OMIM: 609765) PREDICTED: lysine-spec ( 330) 275 50.1 2.9e-05
XP_016869993 (OMIM: 605469) PREDICTED: lysine-spec ( 763) 280 51.1 3.5e-05
XP_016869992 (OMIM: 605469) PREDICTED: lysine-spec ( 793) 280 51.1 3.6e-05
XP_016869991 (OMIM: 605469) PREDICTED: lysine-spec ( 811) 280 51.1 3.6e-05
>>NP_004964 (OMIM: 601594) protein Jumonji isoform 1 [Ho (1246 aa)
initn: 8374 init1: 8374 opt: 8374 Z-score: 6089.7 bits: 1138.9 E(85289): 0
Smith-Waterman score: 8374; 100.0% identity (100.0% similar) in 1246 aa overlap (1-1246:1-1246)
10 20 30 40 50 60
pF1KE0 MSKERPKRNIIQKKYDDSDGIPWSEERVVRKVLYLSLKEFKNSQKRQHAEGIAGSLKTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSKERPKRNIIQKKYDDSDGIPWSEERVVRKVLYLSLKEFKNSQKRQHAEGIAGSLKTVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GLLGNDQSKGLGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPSRKRPRLQAQRKFAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GLLGNDQSKGLGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPSRKRPRLQAQRKFAQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DEEEVEEEDDETEDVKTATNNASSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DEEEVEEEDDETEDVKTATNNASSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 HKSKEATPAKEKHSDHRADSRREQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HKSKEATPAKEKHSDHRADSRREQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KQVSKVNGVTRMSSLGAGVTSAKKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KQVSKVNGVTRMSSLGAGVTSAKKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 KPNHHKPSSAVNHTISGKTESSNAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KPNHHKPSSAVNHTISGKTESSNAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 EVGGRQLREGLQLREGLRNSKRRLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EVGGRQLREGLQLREGLRNSKRRLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 LNGHVKKEVPERSLERNRPKRATAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LNGHVKKEVPERSLERNRPKRATAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 KAEKGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KAEKGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 LNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 LINEMGGMQQVTDLKKWNKLADMLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LINEMGGMQQVTDLKKWNKLADMLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 KEVLMEKEILEKRKGPLEGHTENDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KEVLMEKEILEKRKGPLEGHTENDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 QLKTGRRRLFAQEKEVVKEEEEDKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QLKTGRRRLFAQEKEVVKEEEEDKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 PAPAEIEQEYWRLVEEKDCHVAVHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PAPAEIEQEYWRLVEEKDCHVAVHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 SILRHLGAVPGVTIPWLNIGMVFSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SILRHLGAVPGVTIPWLNIGMVFSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 EDVVHTLLQANGTPGLQMLESNVMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EDVVHTLLQANGTPGLQMLESNVMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 CGYSVSETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CGYSVSETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLST
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 ISALLDELRDTELRQRRQLFEAGLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ISALLDELRDTELRQRRQLFEAGLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 ICQHLCYLSMVVQENENVVFCLECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ICQHLCYLSMVVQENENVVFCLECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKV
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240
pF1KE0 SGKNGSIENCLSKPTPKRGPRKRATVDVPPSRLSASSSSKSASSSS
::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SGKNGSIENCLSKPTPKRGPRKRATVDVPPSRLSASSSSKSASSSS
1210 1220 1230 1240
>>XP_016866322 (OMIM: 601594) PREDICTED: protein Jumonji (1294 aa)
initn: 8360 init1: 8276 opt: 8276 Z-score: 6018.3 bits: 1125.8 E(85289): 0
Smith-Waterman score: 8276; 100.0% identity (100.0% similar) in 1231 aa overlap (16-1246:64-1294)
10 20 30 40
pF1KE0 MSKERPKRNIIQKKYDDSDGIPWSEERVVRKVLYLSLKEFKNSQK
::::::::::::::::::::::::::::::
XP_016 ATDGTLIRLAKKVPFWLTKRMLLKTYCAHQDDSDGIPWSEERVVRKVLYLSLKEFKNSQK
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE0 RQHAEGIAGSLKTVNGLLGNDQSKGLGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQHAEGIAGSLKTVNGLLGNDQSKGLGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPS
100 110 120 130 140 150
110 120 130 140 150 160
pF1KE0 RKRPRLQAQRKFAQSQPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKRPRLQAQRKFAQSQPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRG
160 170 180 190 200 210
170 180 190 200 210 220
pF1KE0 SPALPNSMVYFGSSQDEEEVEEEDDETEDVKTATNNASSSCQSTPRKGKTHKHVHNGHVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPALPNSMVYFGSSQDEEEVEEEDDETEDVKTATNNASSSCQSTPRKGKTHKHVHNGHVF
220 230 240 250 260 270
230 240 250 260 270 280
pF1KE0 NGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRREQASANHPAAAPSTGSSAKGLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRREQASANHPAAAPSTGSSAKGLAA
280 290 300 310 320 330
290 300 310 320 330 340
pF1KE0 THHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSAKKMREVRPSPSKTVKYTATVTKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSAKKMREVRPSPSKTVKYTATVTKG
340 350 360 370 380 390
350 360 370 380 390 400
pF1KE0 AVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESSNAKTRKQVLSLGGASKSTGPAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESSNAKTRKQVLSLGGASKSTGPAVN
400 410 420 430 440 450
410 420 430 440 450 460
pF1KE0 GLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKRRLEEAHQAEKPQSPPKKMKGAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKRRLEEAHQAEKPQSPPKKMKGAAG
460 470 480 490 500 510
470 480 490 500 510 520
pF1KE0 PAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRATAGKSTPGRQAHGKADSASCENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRATAGKSTPGRQAHGKADSASCENR
520 530 540 550 560 570
530 540 550 560 570 580
pF1KE0 STSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFG
580 590 600 610 620 630
590 600 610 620 630 640
pF1KE0 MCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQGITMDEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQGITMDEL
640 650 660 670 680 690
650 660 670 680 690 700
pF1KE0 PLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPRTAQDRLAKLQEAYCQYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPRTAQDRLAKLQEAYCQYL
700 710 720 730 740 750
710 720 730 740 750 760
pF1KE0 LSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTENDHHKFHPLPRFEPKNGLIHGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTENDHHKFHPLPRFEPKNGLIHGVA
760 770 780 790 800 810
770 780 790 800 810 820
pF1KE0 PRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEEDKGVLNDFHKCIYKGRSVSLTTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEEDKGVLNDFHKCIYKGRSVSLTTF
820 830 840 850 860 870
830 840 850 860 870 880
pF1KE0 YRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVAVHCGKVDTNTHGSGFPVGKSEPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVAVHCGKVDTNTHGSGFPVGKSEPF
880 890 900 910 920 930
890 900 910 920 930 940
pF1KE0 SRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMVFSTSCWSRDQNHLPYIDYLHTGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMVFSTSCWSRDQNHLPYIDYLHTGA
940 950 960 970 980 990
950 960 970 980 990 1000
pF1KE0 DCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESNVMISPEVLCKEGIKVHRTVQQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESNVMISPEVLCKEGIKVHRTVQQSG
1000 1010 1020 1030 1040 1050
1010 1020 1030 1040 1050 1060
pF1KE0 QFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQI
1060 1070 1080 1090 1100 1110
1070 1080 1090 1100 1110 1120
pF1KE0 AQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHSSARYGSHDGSSTVADGKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHSSARYGSHDGSSTVADGKKK
1120 1130 1140 1150 1160 1170
1130 1140 1150 1160 1170 1180
pF1KE0 PRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCLECALRHVEKQKSCRGLKLMYRYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCLECALRHVEKQKSCRGLKLMYRYD
1180 1190 1200 1210 1220 1230
1190 1200 1210 1220 1230 1240
pF1KE0 EEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRKRATVDVPPSRLSASSSSKSASSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRKRATVDVPPSRLSASSSSKSASSS
1240 1250 1260 1270 1280 1290
pF1KE0 S
:
XP_016 S
>>XP_011512881 (OMIM: 601594) PREDICTED: protein Jumonji (1309 aa)
initn: 7378 init1: 7294 opt: 7305 Z-score: 5313.0 bits: 995.3 E(85289): 0
Smith-Waterman score: 8236; 98.8% identity (98.8% similar) in 1246 aa overlap (16-1246:64-1309)
10 20 30 40
pF1KE0 MSKERPKRNIIQKKYDDSDGIPWSEERVVRKVLYLSLKEFKNSQK
::::::::::::::::::::::::::::::
XP_011 ATDGTLIRLAKKVPFWLTKRMLLKTYCAHQDDSDGIPWSEERVVRKVLYLSLKEFKNSQK
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE0 RQHAEGIAGSLKTVNGLLGNDQSKGLGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQHAEGIAGSLKTVNGLLGNDQSKGLGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPS
100 110 120 130 140 150
110 120 130 140 150 160
pF1KE0 RKRPRLQAQRKFAQSQPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKRPRLQAQRKFAQSQPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRG
160 170 180 190 200 210
170 180 190 200 210
pF1KE0 ---------------SPALPNSMVYFGSSQDEEEVEEEDDETEDVKTATNNASSSCQSTP
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTLQPSAEVYVESTCSPALPNSMVYFGSSQDEEEVEEEDDETEDVKTATNNASSSCQSTP
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE0 RKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRREQASANHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRREQASANHP
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE0 AAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSAKKMREVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSAKKMREVRP
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE0 SPSKTVKYTATVTKGAVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESSNAKTRKQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPSKTVKYTATVTKGAVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESSNAKTRKQV
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE0 LSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKRRLEEAHQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKRRLEEAHQA
460 470 480 490 500 510
460 470 480 490 500 510
pF1KE0 EKPQSPPKKMKGAAGPAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRATAGKSTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKPQSPPKKMKGAAGPAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRATAGKSTPG
520 530 540 550 560 570
520 530 540 550 560 570
pF1KE0 RQAHGKADSASCENRSTSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRPSAKEFHDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQAHGKADSASCENRSTSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRPSAKEFHDP
580 590 600 610 620 630
580 590 600 610 620 630
pF1KE0 LIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLAC
640 650 660 670 680 690
640 650 660 670 680 690
pF1KE0 IKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPRTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPRTA
700 710 720 730 740 750
700 710 720 730 740 750
pF1KE0 QDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTENDHHKFHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTENDHHKFHP
760 770 780 790 800 810
760 770 780 790 800 810
pF1KE0 LPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEEDKGVLNDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEEDKGVLNDF
820 830 840 850 860 870
820 830 840 850 860 870
pF1KE0 HKCIYKGRSVSLTTFYRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVAVHCGKVDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKCIYKGRSVSLTTFYRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVAVHCGKVDT
880 890 900 910 920 930
880 890 900 910 920 930
pF1KE0 NTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMVFSTSCWSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMVFSTSCWSR
940 950 960 970 980 990
940 950 960 970 980 990
pF1KE0 DQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESNVMISPEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESNVMISPEVL
1000 1010 1020 1030 1040 1050
1000 1010 1020 1030 1040 1050
pF1KE0 CKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFETAKEMKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFETAKEMKRR
1060 1070 1080 1090 1100 1110
1060 1070 1080 1090 1100 1110
pF1KE0 HIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHSSARY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHSSARY
1120 1130 1140 1150 1160 1170
1120 1130 1140 1150 1160 1170
pF1KE0 GSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCLECALRHVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCLECALRHVE
1180 1190 1200 1210 1220 1230
1180 1190 1200 1210 1220 1230
pF1KE0 KQKSCRGLKLMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRKRATVDVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQKSCRGLKLMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRKRATVDVPP
1240 1250 1260 1270 1280 1290
1240
pF1KE0 SRLSASSSSKSASSSS
::::::::::::::::
XP_011 SRLSASSSSKSASSSS
1300
>>XP_016866323 (OMIM: 601594) PREDICTED: protein Jumonji (1074 aa)
initn: 7247 init1: 7247 opt: 7247 Z-score: 5272.0 bits: 987.4 E(85289): 0
Smith-Waterman score: 7247; 100.0% identity (100.0% similar) in 1074 aa overlap (173-1246:1-1074)
150 160 170 180 190 200
pF1KE0 QISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQDEEEVEEEDDETEDVKTATNNA
::::::::::::::::::::::::::::::
XP_016 MVYFGSSQDEEEVEEEDDETEDVKTATNNA
10 20 30
210 220 230 240 250 260
pF1KE0 SSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRR
40 50 60 70 80 90
270 280 290 300 310 320
pF1KE0 EQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSA
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE0 KKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESS
160 170 180 190 200 210
390 400 410 420 430 440
pF1KE0 NAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKR
220 230 240 250 260 270
450 460 470 480 490 500
pF1KE0 RLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRA
280 290 300 310 320 330
510 520 530 540 550 560
pF1KE0 TAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRP
340 350 360 370 380 390
570 580 590 600 610 620
pF1KE0 SAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWG
400 410 420 430 440 450
630 640 650 660 670 680
pF1KE0 PNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLAD
460 470 480 490 500 510
690 700 710 720 730 740
pF1KE0 MLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTE
520 530 540 550 560 570
750 760 770 780 790 800
pF1KE0 NDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEE
580 590 600 610 620 630
810 820 830 840 850 860
pF1KE0 DKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVA
640 650 660 670 680 690
870 880 890 900 910 920
pF1KE0 VHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMV
700 710 720 730 740 750
930 940 950 960 970 980
pF1KE0 FSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESN
760 770 780 790 800 810
990 1000 1010 1020 1030 1040
pF1KE0 VMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFE
820 830 840 850 860 870
1050 1060 1070 1080 1090 1100
pF1KE0 TAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEA
880 890 900 910 920 930
1110 1120 1130 1140 1150 1160
pF1KE0 GLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCL
940 950 960 970 980 990
1170 1180 1190 1200 1210 1220
pF1KE0 ECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRK
1000 1010 1020 1030 1040 1050
1230 1240
pF1KE0 RATVDVPPSRLSASSSSKSASSSS
::::::::::::::::::::::::
XP_016 RATVDVPPSRLSASSSSKSASSSS
1060 1070
>>XP_005249146 (OMIM: 601594) PREDICTED: protein Jumonji (1074 aa)
initn: 7247 init1: 7247 opt: 7247 Z-score: 5272.0 bits: 987.4 E(85289): 0
Smith-Waterman score: 7247; 100.0% identity (100.0% similar) in 1074 aa overlap (173-1246:1-1074)
150 160 170 180 190 200
pF1KE0 QISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQDEEEVEEEDDETEDVKTATNNA
::::::::::::::::::::::::::::::
XP_005 MVYFGSSQDEEEVEEEDDETEDVKTATNNA
10 20 30
210 220 230 240 250 260
pF1KE0 SSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRR
40 50 60 70 80 90
270 280 290 300 310 320
pF1KE0 EQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSA
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE0 KKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESS
160 170 180 190 200 210
390 400 410 420 430 440
pF1KE0 NAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKR
220 230 240 250 260 270
450 460 470 480 490 500
pF1KE0 RLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRA
280 290 300 310 320 330
510 520 530 540 550 560
pF1KE0 TAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRP
340 350 360 370 380 390
570 580 590 600 610 620
pF1KE0 SAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWG
400 410 420 430 440 450
630 640 650 660 670 680
pF1KE0 PNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLAD
460 470 480 490 500 510
690 700 710 720 730 740
pF1KE0 MLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTE
520 530 540 550 560 570
750 760 770 780 790 800
pF1KE0 NDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEE
580 590 600 610 620 630
810 820 830 840 850 860
pF1KE0 DKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVA
640 650 660 670 680 690
870 880 890 900 910 920
pF1KE0 VHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMV
700 710 720 730 740 750
930 940 950 960 970 980
pF1KE0 FSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESN
760 770 780 790 800 810
990 1000 1010 1020 1030 1040
pF1KE0 VMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFE
820 830 840 850 860 870
1050 1060 1070 1080 1090 1100
pF1KE0 TAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEA
880 890 900 910 920 930
1110 1120 1130 1140 1150 1160
pF1KE0 GLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCL
940 950 960 970 980 990
1170 1180 1190 1200 1210 1220
pF1KE0 ECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRK
1000 1010 1020 1030 1040 1050
1230 1240
pF1KE0 RATVDVPPSRLSASSSSKSASSSS
::::::::::::::::::::::::
XP_005 RATVDVPPSRLSASSSSKSASSSS
1060 1070
>>NP_001253969 (OMIM: 601594) protein Jumonji isoform 2 (1074 aa)
initn: 7247 init1: 7247 opt: 7247 Z-score: 5272.0 bits: 987.4 E(85289): 0
Smith-Waterman score: 7247; 100.0% identity (100.0% similar) in 1074 aa overlap (173-1246:1-1074)
150 160 170 180 190 200
pF1KE0 QISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQDEEEVEEEDDETEDVKTATNNA
::::::::::::::::::::::::::::::
NP_001 MVYFGSSQDEEEVEEEDDETEDVKTATNNA
10 20 30
210 220 230 240 250 260
pF1KE0 SSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRR
40 50 60 70 80 90
270 280 290 300 310 320
pF1KE0 EQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSA
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE0 KKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESS
160 170 180 190 200 210
390 400 410 420 430 440
pF1KE0 NAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKR
220 230 240 250 260 270
450 460 470 480 490 500
pF1KE0 RLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRA
280 290 300 310 320 330
510 520 530 540 550 560
pF1KE0 TAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRP
340 350 360 370 380 390
570 580 590 600 610 620
pF1KE0 SAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWG
400 410 420 430 440 450
630 640 650 660 670 680
pF1KE0 PNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLAD
460 470 480 490 500 510
690 700 710 720 730 740
pF1KE0 MLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTE
520 530 540 550 560 570
750 760 770 780 790 800
pF1KE0 NDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEE
580 590 600 610 620 630
810 820 830 840 850 860
pF1KE0 DKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVA
640 650 660 670 680 690
870 880 890 900 910 920
pF1KE0 VHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMV
700 710 720 730 740 750
930 940 950 960 970 980
pF1KE0 FSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESN
760 770 780 790 800 810
990 1000 1010 1020 1030 1040
pF1KE0 VMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFE
820 830 840 850 860 870
1050 1060 1070 1080 1090 1100
pF1KE0 TAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEA
880 890 900 910 920 930
1110 1120 1130 1140 1150 1160
pF1KE0 GLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCL
940 950 960 970 980 990
1170 1180 1190 1200 1210 1220
pF1KE0 ECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRK
1000 1010 1020 1030 1040 1050
1230 1240
pF1KE0 RATVDVPPSRLSASSSSKSASSSS
::::::::::::::::::::::::
NP_001 RATVDVPPSRLSASSSSKSASSSS
1060 1070
>>XP_016866324 (OMIM: 601594) PREDICTED: protein Jumonji (1074 aa)
initn: 7247 init1: 7247 opt: 7247 Z-score: 5272.0 bits: 987.4 E(85289): 0
Smith-Waterman score: 7247; 100.0% identity (100.0% similar) in 1074 aa overlap (173-1246:1-1074)
150 160 170 180 190 200
pF1KE0 QISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQDEEEVEEEDDETEDVKTATNNA
::::::::::::::::::::::::::::::
XP_016 MVYFGSSQDEEEVEEEDDETEDVKTATNNA
10 20 30
210 220 230 240 250 260
pF1KE0 SSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRR
40 50 60 70 80 90
270 280 290 300 310 320
pF1KE0 EQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSA
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE0 KKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESS
160 170 180 190 200 210
390 400 410 420 430 440
pF1KE0 NAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKR
220 230 240 250 260 270
450 460 470 480 490 500
pF1KE0 RLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRA
280 290 300 310 320 330
510 520 530 540 550 560
pF1KE0 TAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRP
340 350 360 370 380 390
570 580 590 600 610 620
pF1KE0 SAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWG
400 410 420 430 440 450
630 640 650 660 670 680
pF1KE0 PNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLAD
460 470 480 490 500 510
690 700 710 720 730 740
pF1KE0 MLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTE
520 530 540 550 560 570
750 760 770 780 790 800
pF1KE0 NDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEE
580 590 600 610 620 630
810 820 830 840 850 860
pF1KE0 DKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVA
640 650 660 670 680 690
870 880 890 900 910 920
pF1KE0 VHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMV
700 710 720 730 740 750
930 940 950 960 970 980
pF1KE0 FSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESN
760 770 780 790 800 810
990 1000 1010 1020 1030 1040
pF1KE0 VMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFE
820 830 840 850 860 870
1050 1060 1070 1080 1090 1100
pF1KE0 TAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEA
880 890 900 910 920 930
1110 1120 1130 1140 1150 1160
pF1KE0 GLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCL
940 950 960 970 980 990
1170 1180 1190 1200 1210 1220
pF1KE0 ECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRK
1000 1010 1020 1030 1040 1050
1230 1240
pF1KE0 RATVDVPPSRLSASSSSKSASSSS
::::::::::::::::::::::::
XP_016 RATVDVPPSRLSASSSSKSASSSS
1060 1070
>>XP_011512886 (OMIM: 601594) PREDICTED: protein Jumonji (826 aa)
initn: 5256 init1: 5256 opt: 5262 Z-score: 3832.0 bits: 720.6 E(85289): 1.1e-206
Smith-Waterman score: 5262; 99.4% identity (99.6% similar) in 783 aa overlap (173-955:1-781)
150 160 170 180 190 200
pF1KE0 QISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQDEEEVEEEDDETEDVKTATNNA
::::::::::::::::::::::::::::::
XP_011 MVYFGSSQDEEEVEEEDDETEDVKTATNNA
10 20 30
210 220 230 240 250 260
pF1KE0 SSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRR
40 50 60 70 80 90
270 280 290 300 310 320
pF1KE0 EQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSA
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE0 KKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESS
160 170 180 190 200 210
390 400 410 420 430 440
pF1KE0 NAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKR
220 230 240 250 260 270
450 460 470 480 490 500
pF1KE0 RLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRA
280 290 300 310 320 330
510 520 530 540 550 560
pF1KE0 TAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRP
340 350 360 370 380 390
570 580 590 600 610 620
pF1KE0 SAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWG
400 410 420 430 440 450
630 640 650 660 670 680
pF1KE0 PNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLAD
460 470 480 490 500 510
690 700 710 720 730 740
pF1KE0 MLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTE
520 530 540 550 560 570
750 760 770 780 790 800
pF1KE0 NDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEE
580 590 600 610 620 630
810 820 830 840 850 860
pF1KE0 DKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVA
640 650 660 670 680 690
870 880 890 900 910 920
pF1KE0 VHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMV
700 710 720 730 740 750
930 940 950 960 970 980
pF1KE0 FSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESN
:::::::::::::::::::::::::: :. .:
XP_011 FSTSCWSRDQNHLPYIDYLHTGADCI--CLSVEPVFPHLSVAVGSRVDLGISFLPCGDTR
760 770 780 790 800
990 1000 1010 1020 1030 1040
pF1KE0 VMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFE
XP_011 VMYPVESVAWRGVLGPRL
810 820
>>XP_011529133 (OMIM: 300534,314690) PREDICTED: lysine-s (1232 aa)
initn: 351 init1: 174 opt: 417 Z-score: 310.7 bits: 69.6 E(85289): 1.4e-10
Smith-Waterman score: 539; 28.7% identity (56.9% similar) in 401 aa overlap (818-1196:62-435)
790 800 810 820 830 840
pF1KE0 RLFAQEKEVVKEEEEDKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSK--EPAPAE
: .: .: . : .. . :. . .:.:
XP_011 EIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTE
40 50 60 70 80 90
850 860 870 880 890
pF1KE0 -IEQEYWRLVEEKDCHVAVHCGK-VDTNTHGSGFPVGKS--------EPFSRHGWNLTVL
.:.:.::::. . :.:. : . .. ::::::. : : .. ::::.:.
XP_011 LVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVM
100 110 120 130 140 150
900 910 920 930 940 950
pF1KE0 PNNTGSILRHLGA-VPGVTIPWLNIGMVFSTSCWSRDQNHLPY-IDYLHTGADCIWYCIP
: :.: :..: . :. .::: .:::::. :: . ..: : :.::: : :: .:
XP_011 PVLEQSVLCHINADISGMKVPWLYVGMVFSAFCW-HIEDHWSYSINYLHWGEPKTWYGVP
160 170 180 190 200 210
960 970 980 990 1000 1010
pF1KE0 AEEENKLEDVVHTLLQA--NGTPGLQMLESNVMISPEVLCKEGIKVHRTVQQSGQFVVCF
. ..::.:.. : .. : : . . ....:..: ..:. : :: : .:.::. :
XP_011 SLAAEHLEEVMKKLTPELFDSQPDL-LHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITF
220 230 240 250 260
1020 1030 1040 1050 1060 1070
pF1KE0 PGSFVSKVCCGYSVSETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQIAQAEAK
: .. : ::. .:.:.: :..: : . ....: . :: :.:. ..: :
XP_011 PRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEK
270 280 290 300 310 320
1080 1090 1100 1110 1120
pF1KE0 KENGPTLSTISALLDELR---DTELRQRRQLFEAGLHSSARYGSHDGSSTVADGKKKPRK
. :. .:. :. . : : :. :.: :. . : .
XP_011 LD----LNLAAAVHKEMFIMVQEERRLRKALLEKGITEAER-----------------EA
330 340 350 360
1130 1140 1150 1160 1170 1180
pF1KE0 WLQLETSERRCQICQHLCYLS-MVVQENENVVFCLECALRHVEKQKSCRGLK--LMYRYD
. : .::.: :. :.:: .. . . . :: :.. .: . . : :::
XP_011 FELLPDDERQCIKCKTTCFLSALACYDCPDGLVCL----SHINDLCKCSSSRQYLRYRYT
370 380 390 400 410 420
1190 1200 1210 1220 1230 1240
pF1KE0 EEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRKRATVDVPPSRLSASSSSKSASSS
... ......
XP_011 LDELPAMLHKLKVRAESFDTWANKVRVALEVEDGRKRSLEELRALESEARERRFPNSELL
430 440 450 460 470 480
>>NP_001140174 (OMIM: 300534,314690) lysine-specific dem (1379 aa)
initn: 475 init1: 174 opt: 417 Z-score: 310.1 bits: 69.7 E(85289): 1.6e-10
Smith-Waterman score: 553; 24.7% identity (51.2% similar) in 722 aa overlap (556-1196:13-696)
530 540 550 560 570 580
pF1KE0 STSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFG
: ::..:: ::.::: :: ..: .:: :
NP_001 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSG
10 20 30 40
590 600 610 620 630
pF1KE0 MCRVIPPP------DWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQG
.:.. :: .. :: . :.. : .:. : :. : ...: .
NP_001 ICKIRPPAIVVEEGGYEAICK---DRRWARVAQ---RLNYPPGKNIGSL--LRSHYER--
50 60 70 80 90
640 650 660 670 680
pF1KE0 ITMDELPLIGGCELDLACFFR-LINEMGG---------MQQVTDLKKWNKLADMLRIPRT
:.. .: .: . : : . :: ..: .. .:.:. . : :
NP_001 IVYPYEMYQSGANL-VQCNTRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGR--RAKRL
100 110 120 130 140
690 700 710 720 730 740
pF1KE0 AQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKR--KGP-------LEGH
: .. . :. .. . . .. . . :.:. .:: .. .
NP_001 QPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEE
150 160 170 180 190 200
750 760 770 780 790
pF1KE0 TENDHHKFHPLPR--FEPKNGLIHGVAPRNGFRSKLKEV-GQAQ-LKTGRRRLFAQEKEV
.: . :. .: :. : :. : . . .:.. ..:: ... :. .. :
NP_001 LGGDVKVESTSPKTFLESKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDED
210 220 230 240 250 260
800 810 820
pF1KE0 VKEEEEDKGVLNDFH-------------------KCIYK---------G-----RSVSLT
: : : ...: ::.. : : .:
NP_001 DKLLLCD-GCDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQ
270 280 290 300 310 320
830 840 850 860 870
pF1KE0 TFYRTARNIMSMCFSK--EPAPAE-IEQEYWRLVEEKDCHVAVHCGK-VDTNTHGSGFPV
.: . : .. . :. . .:.: .:.:.::::. . :.:. : . .. ::::::
NP_001 SFGEMADSFKADYFNMPVHMVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPV
330 340 350 360 370 380
880 890 900 910 920 930
pF1KE0 GKS--------EPFSRHGWNLTVLPNNTGSILRHLGA-VPGVTIPWLNIGMVFSTSCWSR
. : : .. ::::.:.: :.: :..: . :. .::: .:::::. :: .
NP_001 SDSKRHLTPEEEEYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCW-H
390 400 410 420 430 440
940 950 960 970 980
pF1KE0 DQNHLPY-IDYLHTGADCIWYCIPAEEENKLEDVVHTLLQA--NGTPGLQMLESNVMISP
..: : :.::: : :: .:. ..::.:.. : .. : : . . ....:
NP_001 IEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDL-LHQLVTLMNP
450 460 470 480 490 500
990 1000 1010 1020 1030 1040
pF1KE0 EVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFETAKEM
..: ..:. : :: : .:.::. :: .. : ::. .:.:.: :..: : . ...
NP_001 NTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHY
510 520 530 540 550 560
1050 1060 1070 1080 1090 1100
pF1KE0 KRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHSS
.: . :: :.:. ..: : .: . ... . . . : : :. :.: :. .
NP_001 RRLRRYCVFSHEELICKMA-ACPEKLDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEA
570 580 590 600 610 620
1110 1120 1130 1140 1150 1160
pF1KE0 ARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLS-MVVQENENVVFCLECAL
: . . : .::.: :. :.:: .. . . . ::
NP_001 ER-----------------EAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCL----
630 640 650 660
1170 1180 1190 1200 1210 1220
pF1KE0 RHVEKQKSCRGLK--LMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRKRA
:.. .: . . : ::: ... ......
NP_001 SHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVALEVEDGRKRSL
670 680 690 700 710 720
1230 1240
pF1KE0 TVDVPPSRLSASSSSKSASSSS
NP_001 EELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGPHRVAGLQMTLT
730 740 750 760 770 780
1246 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 20:10:58 2016 done: Sun Nov 6 20:11:01 2016
Total Scan time: 17.630 Total Display time: 0.500
Function used was FASTA [36.3.4 Apr, 2011]