Result of FASTA (omim) for
pFN21AE0897
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0897, 255 aa
1>>>pF1KE0897 255 - 255 aa - 255 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8244+/-0.000412; mu= 7.8591+/- 0.026
mean_var=115.9732+/-23.076, 0's: 0 Z-trim(114.2): 80 B-trim: 543 in 2/52
Lambda= 0.119096
statistics sampled from 23832 (23907) to 23832 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.28), width: 16
Scan time: 5.720
The best scores are: opt bits E(85289)
NP_005810 (OMIM: 603944) syntaxin-6 isoform 1 [Hom ( 255) 1622 289.5 3.9e-78
XP_011507360 (OMIM: 603944) PREDICTED: syntaxin-6 ( 271) 1464 262.4 6.2e-70
NP_003756 (OMIM: 603765) syntaxin-10 isoform 1 [Ho ( 249) 1000 182.6 5.7e-46
XP_016855496 (OMIM: 603944) PREDICTED: syntaxin-6 ( 154) 970 177.3 1.4e-44
NP_001273139 (OMIM: 603944) syntaxin-6 isoform 2 [ ( 154) 970 177.3 1.4e-44
NP_001258539 (OMIM: 603765) syntaxin-10 isoform 3 ( 246) 879 161.8 1e-39
XP_016855495 (OMIM: 603944) PREDICTED: syntaxin-6 ( 170) 812 150.2 2.2e-36
XP_011507361 (OMIM: 603944) PREDICTED: syntaxin-6 ( 170) 812 150.2 2.2e-36
NP_001258538 (OMIM: 603765) syntaxin-10 isoform 2 ( 220) 744 138.6 9e-33
XP_011526699 (OMIM: 603765) PREDICTED: syntaxin-10 ( 131) 533 102.2 4.9e-22
NP_001258540 (OMIM: 603765) syntaxin-10 isoform 4 ( 200) 477 92.7 5.4e-19
NP_004844 (OMIM: 604203) syntaxin-8 [Homo sapiens] ( 236) 181 41.9 0.0013
XP_011522381 (OMIM: 604203) PREDICTED: syntaxin-8 ( 181) 179 41.5 0.0013
>>NP_005810 (OMIM: 603944) syntaxin-6 isoform 1 [Homo sa (255 aa)
initn: 1622 init1: 1622 opt: 1622 Z-score: 1523.7 bits: 289.5 E(85289): 3.9e-78
Smith-Waterman score: 1622; 100.0% identity (100.0% similar) in 255 aa overlap (1-255:1-255)
10 20 30 40 50 60
pF1KE0 MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAI
190 200 210 220 230 240
250
pF1KE0 LFAVLLVVLILFLVL
:::::::::::::::
NP_005 LFAVLLVVLILFLVL
250
>>XP_011507360 (OMIM: 603944) PREDICTED: syntaxin-6 isof (271 aa)
initn: 1464 init1: 1464 opt: 1464 Z-score: 1376.6 bits: 262.4 E(85289): 6.2e-70
Smith-Waterman score: 1464; 100.0% identity (100.0% similar) in 230 aa overlap (1-230:1-230)
10 20 30 40 50 60
pF1KE0 MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAI
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSVLEAVAFDQA
190 200 210 220 230 240
250
pF1KE0 LFAVLLVVLILFLVL
XP_011 WDQEVRPALRHQPKDPLNLPSPPANKGTSRC
250 260 270
>>NP_003756 (OMIM: 603765) syntaxin-10 isoform 1 [Homo s (249 aa)
initn: 1042 init1: 551 opt: 1000 Z-score: 946.2 bits: 182.6 E(85289): 5.7e-46
Smith-Waterman score: 1000; 61.2% identity (84.7% similar) in 255 aa overlap (1-255:1-249)
10 20 30 40 50 60
pF1KE0 MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWD
::.:::::::.::::::::::.::.::: ::::. ... :::.:::::::::.:::::::
NP_003 MSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQESAAVGREELDWTTNELRNGLRSIEWD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNR
::::.:::.:::::: ::.: : .:. ::.:. :..:..:::.: . .. :. ::.::
NP_003 LEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI
. : : ..:. . .: :: :.:..:::::: ::::...::.:::.:::::
NP_003 EILAGKPAAQK---SPSDL---LDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSI
130 140 150 160 170
190 200 210 220 230 240
pF1KE0 GVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAI
:::.:: :.: ::.::..::. :..:.. ::::.:.:..:::::::::::::::::::.
NP_003 QVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAKVSHMTSDRRQWCAIAV
180 190 200 210 220 230
250
pF1KE0 LFAVLLVVLILFLVL
: .:::.::::.. :
NP_003 LVGVLLLVLILLFSL
240
>>XP_016855496 (OMIM: 603944) PREDICTED: syntaxin-6 isof (154 aa)
initn: 970 init1: 970 opt: 970 Z-score: 921.4 bits: 177.3 E(85289): 1.4e-44
Smith-Waterman score: 970; 100.0% identity (100.0% similar) in 154 aa overlap (102-255:1-154)
80 90 100 110 120 130
pF1KE0 EANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQN
::::::::::::::::::::::::::::::
XP_016 MKDQMSTSSVQALAERKNRQALLGDSGSQN
10 20 30
140 150 160 170 180 190
pF1KE0 WSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIG
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE0 GELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAILFAVLLVVLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAILFAVLLVVLIL
100 110 120 130 140 150
pF1KE0 FLVL
::::
XP_016 FLVL
>>NP_001273139 (OMIM: 603944) syntaxin-6 isoform 2 [Homo (154 aa)
initn: 970 init1: 970 opt: 970 Z-score: 921.4 bits: 177.3 E(85289): 1.4e-44
Smith-Waterman score: 970; 100.0% identity (100.0% similar) in 154 aa overlap (102-255:1-154)
80 90 100 110 120 130
pF1KE0 EANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQN
::::::::::::::::::::::::::::::
NP_001 MKDQMSTSSVQALAERKNRQALLGDSGSQN
10 20 30
140 150 160 170 180 190
pF1KE0 WSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIG
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE0 GELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAILFAVLLVVLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAILFAVLLVVLIL
100 110 120 130 140 150
pF1KE0 FLVL
::::
NP_001 FLVL
>>NP_001258539 (OMIM: 603765) syntaxin-10 isoform 3 [Hom (246 aa)
initn: 891 init1: 549 opt: 879 Z-score: 834.0 bits: 161.8 E(85289): 1e-39
Smith-Waterman score: 879; 60.0% identity (83.9% similar) in 230 aa overlap (1-230:1-224)
10 20 30 40 50 60
pF1KE0 MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWD
::.:::::::.::::::::::.::.::: ::::. ... :::.:::::::::.:::::::
NP_001 MSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQESAAVGREELDWTTNELRNGLRSIEWD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNR
::::.:::.:::::: ::.: : .:. ::.:. :..:..:::.: . .. :. ::.::
NP_001 LEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI
. : : ..:. . .: :: :.:..:::::: ::::...::.:::.:::::
NP_001 EILAGKPAAQK---SPSDL---LDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSI
130 140 150 160 170
190 200 210 220 230 240
pF1KE0 GVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAI
:::.:: :.: ::.::..::. :..:.. ::::.:.:..::::::::::
NP_001 QVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAKVSHMTSGESPQGRGQS
180 190 200 210 220 230
250
pF1KE0 LFAVLLVVLILFLVL
NP_001 WWGQVVGGTLSP
240
>>XP_016855495 (OMIM: 603944) PREDICTED: syntaxin-6 isof (170 aa)
initn: 812 init1: 812 opt: 812 Z-score: 774.1 bits: 150.2 E(85289): 2.2e-36
Smith-Waterman score: 812; 100.0% identity (100.0% similar) in 129 aa overlap (102-230:1-129)
80 90 100 110 120 130
pF1KE0 EANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQN
::::::::::::::::::::::::::::::
XP_016 MKDQMSTSSVQALAERKNRQALLGDSGSQN
10 20 30
140 150 160 170 180 190
pF1KE0 WSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIG
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE0 GELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAILFAVLLVVLIL
:::::::::::::::::::::::::::::::::::::::
XP_016 GELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSVLEAVAFDQAWDQEVRPALRH
100 110 120 130 140 150
pF1KE0 FLVL
XP_016 QPKDPLNLPSPPANKGTSRC
160 170
>>XP_011507361 (OMIM: 603944) PREDICTED: syntaxin-6 isof (170 aa)
initn: 812 init1: 812 opt: 812 Z-score: 774.1 bits: 150.2 E(85289): 2.2e-36
Smith-Waterman score: 812; 100.0% identity (100.0% similar) in 129 aa overlap (102-230:1-129)
80 90 100 110 120 130
pF1KE0 EANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQN
::::::::::::::::::::::::::::::
XP_011 MKDQMSTSSVQALAERKNRQALLGDSGSQN
10 20 30
140 150 160 170 180 190
pF1KE0 WSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIG
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE0 GELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAILFAVLLVVLIL
:::::::::::::::::::::::::::::::::::::::
XP_011 GELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSVLEAVAFDQAWDQEVRPALRH
100 110 120 130 140 150
pF1KE0 FLVL
XP_011 QPKDPLNLPSPPANKGTSRC
160 170
>>NP_001258538 (OMIM: 603765) syntaxin-10 isoform 2 [Hom (220 aa)
initn: 756 init1: 549 opt: 744 Z-score: 709.3 bits: 138.6 E(85289): 9e-33
Smith-Waterman score: 744; 59.2% identity (81.6% similar) in 201 aa overlap (1-201:1-195)
10 20 30 40 50 60
pF1KE0 MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWD
::.:::::::.::::::::::.::.::: ::::. ... :::.:::::::::.:::::::
NP_001 MSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQESAAVGREELDWTTNELRNGLRSIEWD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNR
::::.:::.:::::: ::.: : .:. ::.:. :..:..:::.: . .. :. ::.::
NP_001 LEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI
. : : ..:. . .: :: :.:..:::::: ::::...::.:::.:::::
NP_001 EILAGKPAAQK---SPSDL---LDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSI
130 140 150 160 170
190 200 210 220 230 240
pF1KE0 GVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAI
:::.:: :.: ::.::: .
NP_001 QVLKHMSGRVGEELDEQACWMPSPKRWTTPSPAWTGSSGSWPKYPT
180 190 200 210 220
>>XP_011526699 (OMIM: 603765) PREDICTED: syntaxin-10 iso (131 aa)
initn: 533 init1: 533 opt: 533 Z-score: 516.7 bits: 102.2 E(85289): 4.9e-22
Smith-Waterman score: 533; 65.3% identity (88.4% similar) in 121 aa overlap (1-121:1-121)
10 20 30 40 50 60
pF1KE0 MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWD
::.:::::::.::::::::::.::.::: ::::. ... :::.:::::::::.:::::::
XP_011 MSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQESAAVGREELDWTTNELRNGLRSIEWD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNR
::::.:::.:::::: ::.: : .:. ::.:. :..:..:::.: . .. :. ::.::
XP_011 LEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI
.
XP_011 EMRKLRHKEAK
130
255 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:00:19 2016 done: Mon Nov 7 02:00:20 2016
Total Scan time: 5.720 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]