Result of FASTA (omim) for
pFN21AE0811
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0811, 375 aa
1>>>pF1KE0811 375 - 375 aa - 375 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.4724+/-0.000306; mu= 23.0514+/- 0.019
mean_var=114.0929+/-27.695, 0's: 0 Z-trim(118.9): 232 B-trim: 1709 in 1/50
Lambda= 0.120073
statistics sampled from 31848 (32251) to 31848 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.378), width: 16
Scan time: 8.530
The best scores are: opt bits E(85289)
NP_061844 (OMIM: 605187) probable G-protein couple ( 375) 2555 453.4 4e-127
NP_061842 (OMIM: 300253) probable G-protein couple ( 373) 1379 249.6 8.5e-66
XP_011529100 (OMIM: 300253) PREDICTED: probable G- ( 373) 1379 249.6 8.5e-66
NP_001139739 (OMIM: 605188) probable G-protein cou ( 370) 1322 239.8 8e-63
NP_061843 (OMIM: 605188) probable G-protein couple ( 370) 1322 239.8 8e-63
XP_005250508 (OMIM: 605188) PREDICTED: probable G- ( 370) 1322 239.8 8e-63
XP_016867841 (OMIM: 605188) PREDICTED: probable G- ( 370) 1322 239.8 8e-63
NP_001139738 (OMIM: 605188) probable G-protein cou ( 370) 1322 239.8 8e-63
NP_001139737 (OMIM: 605188) probable G-protein cou ( 370) 1322 239.8 8e-63
NP_387512 (OMIM: 126451,181500,190300) D(3) dopami ( 367) 286 60.3 8.4e-09
NP_001243689 (OMIM: 312861) 5-hydroxytryptamine re ( 458) 282 59.7 1.5e-08
NP_000859 (OMIM: 312861) 5-hydroxytryptamine recep ( 458) 282 59.7 1.5e-08
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 268 57.3 8.4e-08
NP_000016 (OMIM: 109691,601665) beta-3 adrenergic ( 408) 253 54.6 4.7e-07
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425) 249 54.0 7.7e-07
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425) 249 54.0 7.7e-07
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425) 249 54.0 7.7e-07
XP_011541141 (OMIM: 125853,600804) PREDICTED: mela ( 362) 223 49.4 1.6e-05
NP_005950 (OMIM: 125853,600804) melatonin receptor ( 362) 223 49.4 1.6e-05
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 208 46.8 9.8e-05
NP_057658 (OMIM: 126450,159900) D(2) dopamine rece ( 414) 208 46.8 0.0001
NP_000786 (OMIM: 126450,159900) D(2) dopamine rece ( 443) 208 46.9 0.00011
XP_016872785 (OMIM: 126450,159900) PREDICTED: D(2) ( 443) 208 46.9 0.00011
NP_001307687 (OMIM: 601122) 5-hydroxytryptamine re ( 439) 206 46.5 0.00014
NP_005289 (OMIM: 602174) probable G-protein couple ( 361) 205 46.2 0.00014
XP_006712545 (OMIM: 601122) PREDICTED: 5-hydroxytr ( 456) 206 46.6 0.00014
NP_000858 (OMIM: 601122) 5-hydroxytryptamine recep ( 481) 206 46.6 0.00014
NP_000855 (OMIM: 182133) 5-hydroxytryptamine recep ( 377) 204 46.1 0.00016
XP_016877087 (OMIM: 607970) PREDICTED: probable G- ( 494) 201 45.8 0.00027
XP_016877088 (OMIM: 607970) PREDICTED: probable G- ( 494) 201 45.8 0.00027
XP_016877086 (OMIM: 607970) PREDICTED: probable G- ( 494) 201 45.8 0.00027
XP_016877085 (OMIM: 607970) PREDICTED: probable G- ( 494) 201 45.8 0.00027
NP_072093 (OMIM: 607970) probable G-protein couple ( 494) 201 45.8 0.00027
NP_000787 (OMIM: 126451,181500,190300) D(3) dopami ( 400) 199 45.3 0.0003
NP_001269492 (OMIM: 126451,181500,190300) D(3) dop ( 400) 199 45.3 0.0003
XP_016861318 (OMIM: 126451,181500,190300) PREDICTE ( 400) 199 45.3 0.0003
NP_001277738 (OMIM: 126451,181500,190300) D(3) dop ( 400) 199 45.3 0.0003
NP_001304958 (OMIM: 118445) gastrin/cholecystokini ( 363) 193 44.2 0.00059
XP_016874005 (OMIM: 118445) PREDICTED: gastrin/cho ( 381) 193 44.2 0.0006
NP_795344 (OMIM: 118445) gastrin/cholecystokinin t ( 447) 193 44.3 0.00066
XP_005253267 (OMIM: 118445) PREDICTED: gastrin/cho ( 516) 190 43.9 0.001
NP_001309137 (OMIM: 182134) 5-hydroxytryptamine re ( 366) 187 43.1 0.0012
XP_011531966 (OMIM: 182134) PREDICTED: 5-hydroxytr ( 366) 187 43.1 0.0012
XP_005264808 (OMIM: 182134) PREDICTED: 5-hydroxytr ( 366) 187 43.1 0.0012
NP_001309138 (OMIM: 182134) 5-hydroxytryptamine re ( 366) 187 43.1 0.0012
NP_000857 (OMIM: 182134) 5-hydroxytryptamine recep ( 366) 187 43.1 0.0012
NP_001309139 (OMIM: 182134) 5-hydroxytryptamine re ( 366) 187 43.1 0.0012
NP_000788 (OMIM: 126452,143465,601696) D(4) dopami ( 419) 183 42.5 0.0021
NP_000785 (OMIM: 126449) D(1A) dopamine receptor [ ( 446) 183 42.6 0.0022
NP_000625 (OMIM: 146929,609423) C-X-C chemokine re ( 350) 179 41.7 0.0031
>>NP_061844 (OMIM: 605187) probable G-protein coupled re (375 aa)
initn: 2555 init1: 2555 opt: 2555 Z-score: 2403.2 bits: 453.4 E(85289): 4e-127
Smith-Waterman score: 2555; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)
10 20 30 40 50 60
pF1KE0 MANASEPGGSGGGEAAALGLKLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MANASEPGGSGGGEAAALGLKLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLLDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 CLADGLRALACLPAVMLAARRAAAAAGAPPGALGCKLLAFLAALFCFHAAFLLLGVGVTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 CLADGLRALACLPAVMLAARRAAAAAGAPPGALGCKLLAFLAALFCFHAAFLLLGVGVTR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 YLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGDDEDAPCALEQRPDGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 YLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGDDEDAPCALEQRPDGA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 PGALGFLLLLAVVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGATGQAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PGALGFLLLLAVVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGATGQAAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 NWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAVTLLFLLLWGPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 NWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAVTLLFLLLWGPY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 VVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPCCQSPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 VVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPCCQSPR
310 320 330 340 350 360
370
pF1KE0 TTQATHPCDLKGIGL
:::::::::::::::
NP_061 TTQATHPCDLKGIGL
370
>>NP_061842 (OMIM: 300253) probable G-protein coupled re (373 aa)
initn: 970 init1: 398 opt: 1379 Z-score: 1302.2 bits: 249.6 E(85289): 8.5e-66
Smith-Waterman score: 1379; 54.7% identity (83.4% similar) in 362 aa overlap (1-355:1-357)
10 20 30 40 50
pF1KE0 MANAS-EP---GGSGGGEAAALGLKLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYL
:::.. :: .:. . .:. .::. :.:..:::::::....::...::.::.::::.
NP_061 MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 LLDLCLADGLRALACLPAVMLAARRAAAAAGAPPGALGCKLLAFLAALFCFHAAFLLLGV
:::::::::.:. .:.: :. ..:.... . . ::.::..::.:.::::::::.:. .
NP_061 LLDLCLADGIRSAVCFPFVLASVRHGSSWTFS---ALSCKIVAFMAVLFCFHAAFMLFCI
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 GVTRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGDD---EDAPCAL
.::::.:::::::::.:.. : :::. .: ::.:..: :::::.: : :. : .
NP_061 SVTRYMAIAHHRFYAKRMTLWTCAAV-ICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 EQRPDGAPGALGFLLLLAVVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPG
:.: : .:::.:.:::...::: :: .::.: . .:::.:...:::.:..:::::::
NP_061 EHRYFKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 ATGQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAVTLLF
::::::::: ::::::: ::.:.::: : . ..:::: ..: : ::.: .::::.::::
NP_061 ATGQAAANWIAGFGRGPMPPTLLGIRQNGHA-ASRRLLGMDEVKGEKQLGRMFYAITLLF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 LLLWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQF
::::.::.:: : ::.:. :::. ::...::..::::..::.::::.:..:. :.:..
NP_061 LLLWSPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHA
300 310 320 330 340 350
360 370
pF1KE0 PCCQSPRTTQATHPCDLKGIGL
::
NP_061 PCWGTGGAPAPREPYCVM
360 370
>>XP_011529100 (OMIM: 300253) PREDICTED: probable G-prot (373 aa)
initn: 970 init1: 398 opt: 1379 Z-score: 1302.2 bits: 249.6 E(85289): 8.5e-66
Smith-Waterman score: 1379; 54.7% identity (83.4% similar) in 362 aa overlap (1-355:1-357)
10 20 30 40 50
pF1KE0 MANAS-EP---GGSGGGEAAALGLKLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYL
:::.. :: .:. . .:. .::. :.:..:::::::....::...::.::.::::.
XP_011 MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 LLDLCLADGLRALACLPAVMLAARRAAAAAGAPPGALGCKLLAFLAALFCFHAAFLLLGV
:::::::::.:. .:.: :. ..:.... . . ::.::..::.:.::::::::.:. .
XP_011 LLDLCLADGIRSAVCFPFVLASVRHGSSWTFS---ALSCKIVAFMAVLFCFHAAFMLFCI
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 GVTRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGDD---EDAPCAL
.::::.:::::::::.:.. : :::. .: ::.:..: :::::.: : :. : .
XP_011 SVTRYMAIAHHRFYAKRMTLWTCAAV-ICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 EQRPDGAPGALGFLLLLAVVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPG
:.: : .:::.:.:::...::: :: .::.: . .:::.:...:::.:..:::::::
XP_011 EHRYFKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 ATGQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAVTLLF
::::::::: ::::::: ::.:.::: : . ..:::: ..: : ::.: .::::.::::
XP_011 ATGQAAANWIAGFGRGPMPPTLLGIRQNGHA-ASRRLLGMDEVKGEKQLGRMFYAITLLF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 LLLWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQF
::::.::.:: : ::.:. :::. ::...::..::::..::.::::.:..:. :.:..
XP_011 LLLWSPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHA
300 310 320 330 340 350
360 370
pF1KE0 PCCQSPRTTQATHPCDLKGIGL
::
XP_011 PCWGTGGAPAPREPYCVM
360 370
>>NP_001139739 (OMIM: 605188) probable G-protein coupled (370 aa)
initn: 1263 init1: 802 opt: 1322 Z-score: 1248.9 bits: 239.8 E(85289): 8e-63
Smith-Waterman score: 1322; 55.2% identity (82.3% similar) in 344 aa overlap (20-360:22-361)
10 20 30 40 50
pF1KE0 MANASEPGGSGGGEAAALGLKLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLL
:::..:.... ::..::.:...:.:....:::::::.::
NP_001 MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 DLCLADGLRALACLPAVMLAARRAAAAAGAPPGALGCKLLAFLAALFCFHAAFLLLGVGV
::: .: ::. :.: :. ... ... . :.: ::..:::..: :::.::.:. ..:
NP_001 DLCCSDILRSAICFPFVFNSVKNGSTWTY---GTLTCKVIAFLGVLSCFHTAFMLFCISV
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGDD---EDAPCALEQ
::::::::::::..::. : : :. .: .:.:..: ::::::: : . :. :....
NP_001 TRYLAIAHHRFYTKRLTFWTCLAV-ICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 RPDGAPGALGFLLLLAVVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGAT
: : .:::.::::... ::.::::.:.::.::::::.:...: :::..::::::::.
NP_001 RSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGAS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 GQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAVTLLFLL
::::::: ::::::::::.:.::: . : ::::::.::: :::. .::: .:.:::
NP_001 GQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 LWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPC
:::::.:: : ::..: .:: ..:::.::..:::::::: ::.. ::::: :: . .
NP_001 LWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLY
300 310 320 330 340 350
360 370
pF1KE0 CQSPRTTQATHPCDLKGIGL
:.. :
NP_001 CRKSRLPREPYCVI
360 370
>>NP_061843 (OMIM: 605188) probable G-protein coupled re (370 aa)
initn: 1263 init1: 802 opt: 1322 Z-score: 1248.9 bits: 239.8 E(85289): 8e-63
Smith-Waterman score: 1322; 55.2% identity (82.3% similar) in 344 aa overlap (20-360:22-361)
10 20 30 40 50
pF1KE0 MANASEPGGSGGGEAAALGLKLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLL
:::..:.... ::..::.:...:.:....:::::::.::
NP_061 MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 DLCLADGLRALACLPAVMLAARRAAAAAGAPPGALGCKLLAFLAALFCFHAAFLLLGVGV
::: .: ::. :.: :. ... ... . :.: ::..:::..: :::.::.:. ..:
NP_061 DLCCSDILRSAICFPFVFNSVKNGSTWTY---GTLTCKVIAFLGVLSCFHTAFMLFCISV
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGDD---EDAPCALEQ
::::::::::::..::. : : :. .: .:.:..: ::::::: : . :. :....
NP_061 TRYLAIAHHRFYTKRLTFWTCLAV-ICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 RPDGAPGALGFLLLLAVVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGAT
: : .:::.::::... ::.::::.:.::.::::::.:...: :::..::::::::.
NP_061 RSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGAS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 GQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAVTLLFLL
::::::: ::::::::::.:.::: . : ::::::.::: :::. .::: .:.:::
NP_061 GQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 LWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPC
:::::.:: : ::..: .:: ..:::.::..:::::::: ::.. ::::: :: . .
NP_061 LWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLY
300 310 320 330 340 350
360 370
pF1KE0 CQSPRTTQATHPCDLKGIGL
:.. :
NP_061 CRKSRLPREPYCVI
360 370
>>XP_005250508 (OMIM: 605188) PREDICTED: probable G-prot (370 aa)
initn: 1263 init1: 802 opt: 1322 Z-score: 1248.9 bits: 239.8 E(85289): 8e-63
Smith-Waterman score: 1322; 55.2% identity (82.3% similar) in 344 aa overlap (20-360:22-361)
10 20 30 40 50
pF1KE0 MANASEPGGSGGGEAAALGLKLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLL
:::..:.... ::..::.:...:.:....:::::::.::
XP_005 MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 DLCLADGLRALACLPAVMLAARRAAAAAGAPPGALGCKLLAFLAALFCFHAAFLLLGVGV
::: .: ::. :.: :. ... ... . :.: ::..:::..: :::.::.:. ..:
XP_005 DLCCSDILRSAICFPFVFNSVKNGSTWTY---GTLTCKVIAFLGVLSCFHTAFMLFCISV
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGDD---EDAPCALEQ
::::::::::::..::. : : :. .: .:.:..: ::::::: : . :. :....
XP_005 TRYLAIAHHRFYTKRLTFWTCLAV-ICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 RPDGAPGALGFLLLLAVVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGAT
: : .:::.::::... ::.::::.:.::.::::::.:...: :::..::::::::.
XP_005 RSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGAS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 GQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAVTLLFLL
::::::: ::::::::::.:.::: . : ::::::.::: :::. .::: .:.:::
XP_005 GQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 LWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPC
:::::.:: : ::..: .:: ..:::.::..:::::::: ::.. ::::: :: . .
XP_005 LWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLY
300 310 320 330 340 350
360 370
pF1KE0 CQSPRTTQATHPCDLKGIGL
:.. :
XP_005 CRKSRLPREPYCVI
360 370
>>XP_016867841 (OMIM: 605188) PREDICTED: probable G-prot (370 aa)
initn: 1263 init1: 802 opt: 1322 Z-score: 1248.9 bits: 239.8 E(85289): 8e-63
Smith-Waterman score: 1322; 55.2% identity (82.3% similar) in 344 aa overlap (20-360:22-361)
10 20 30 40 50
pF1KE0 MANASEPGGSGGGEAAALGLKLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLL
:::..:.... ::..::.:...:.:....:::::::.::
XP_016 MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 DLCLADGLRALACLPAVMLAARRAAAAAGAPPGALGCKLLAFLAALFCFHAAFLLLGVGV
::: .: ::. :.: :. ... ... . :.: ::..:::..: :::.::.:. ..:
XP_016 DLCCSDILRSAICFPFVFNSVKNGSTWTY---GTLTCKVIAFLGVLSCFHTAFMLFCISV
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGDD---EDAPCALEQ
::::::::::::..::. : : :. .: .:.:..: ::::::: : . :. :....
XP_016 TRYLAIAHHRFYTKRLTFWTCLAV-ICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 RPDGAPGALGFLLLLAVVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGAT
: : .:::.::::... ::.::::.:.::.::::::.:...: :::..::::::::.
XP_016 RSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGAS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 GQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAVTLLFLL
::::::: ::::::::::.:.::: . : ::::::.::: :::. .::: .:.:::
XP_016 GQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 LWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPC
:::::.:: : ::..: .:: ..:::.::..:::::::: ::.. ::::: :: . .
XP_016 LWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLY
300 310 320 330 340 350
360 370
pF1KE0 CQSPRTTQATHPCDLKGIGL
:.. :
XP_016 CRKSRLPREPYCVI
360 370
>>NP_001139738 (OMIM: 605188) probable G-protein coupled (370 aa)
initn: 1263 init1: 802 opt: 1322 Z-score: 1248.9 bits: 239.8 E(85289): 8e-63
Smith-Waterman score: 1322; 55.2% identity (82.3% similar) in 344 aa overlap (20-360:22-361)
10 20 30 40 50
pF1KE0 MANASEPGGSGGGEAAALGLKLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLL
:::..:.... ::..::.:...:.:....:::::::.::
NP_001 MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 DLCLADGLRALACLPAVMLAARRAAAAAGAPPGALGCKLLAFLAALFCFHAAFLLLGVGV
::: .: ::. :.: :. ... ... . :.: ::..:::..: :::.::.:. ..:
NP_001 DLCCSDILRSAICFPFVFNSVKNGSTWTY---GTLTCKVIAFLGVLSCFHTAFMLFCISV
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGDD---EDAPCALEQ
::::::::::::..::. : : :. .: .:.:..: ::::::: : . :. :....
NP_001 TRYLAIAHHRFYTKRLTFWTCLAV-ICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 RPDGAPGALGFLLLLAVVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGAT
: : .:::.::::... ::.::::.:.::.::::::.:...: :::..::::::::.
NP_001 RSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGAS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 GQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAVTLLFLL
::::::: ::::::::::.:.::: . : ::::::.::: :::. .::: .:.:::
NP_001 GQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 LWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPC
:::::.:: : ::..: .:: ..:::.::..:::::::: ::.. ::::: :: . .
NP_001 LWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLY
300 310 320 330 340 350
360 370
pF1KE0 CQSPRTTQATHPCDLKGIGL
:.. :
NP_001 CRKSRLPREPYCVI
360 370
>>NP_001139737 (OMIM: 605188) probable G-protein coupled (370 aa)
initn: 1263 init1: 802 opt: 1322 Z-score: 1248.9 bits: 239.8 E(85289): 8e-63
Smith-Waterman score: 1322; 55.2% identity (82.3% similar) in 344 aa overlap (20-360:22-361)
10 20 30 40 50
pF1KE0 MANASEPGGSGGGEAAALGLKLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLL
:::..:.... ::..::.:...:.:....:::::::.::
NP_001 MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 DLCLADGLRALACLPAVMLAARRAAAAAGAPPGALGCKLLAFLAALFCFHAAFLLLGVGV
::: .: ::. :.: :. ... ... . :.: ::..:::..: :::.::.:. ..:
NP_001 DLCCSDILRSAICFPFVFNSVKNGSTWTY---GTLTCKVIAFLGVLSCFHTAFMLFCISV
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGDD---EDAPCALEQ
::::::::::::..::. : : :. .: .:.:..: ::::::: : . :. :....
NP_001 TRYLAIAHHRFYTKRLTFWTCLAV-ICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 RPDGAPGALGFLLLLAVVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGAT
: : .:::.::::... ::.::::.:.::.::::::.:...: :::..::::::::.
NP_001 RSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGAS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 GQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAVTLLFLL
::::::: ::::::::::.:.::: . : ::::::.::: :::. .::: .:.:::
NP_001 GQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 LWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPC
:::::.:: : ::..: .:: ..:::.::..:::::::: ::.. ::::: :: . .
NP_001 LWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLY
300 310 320 330 340 350
360 370
pF1KE0 CQSPRTTQATHPCDLKGIGL
:.. :
NP_001 CRKSRLPREPYCVI
360 370
>>NP_387512 (OMIM: 126451,181500,190300) D(3) dopamine r (367 aa)
initn: 202 init1: 87 opt: 286 Z-score: 279.0 bits: 60.3 E(85289): 8.4e-09
Smith-Waterman score: 286; 23.7% identity (52.6% similar) in 346 aa overlap (22-355:34-367)
10 20 30 40 50
pF1KE0 MANASEPGGSGGGEAAALGLKLATLSLLLCVSLAGNVLFALLIVRERSLHR
:. .:.: . . :: : . ...::.:.
NP_387 LSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVF-GNGLVCMAVLKERALQT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 APYYLLLDLCLADGLRALACLPAVMLAARRAAAAAGAPPGALGCKLLAFLAALFCFHAAF
. ::...: .:: : : .: :. ... . . : ... : ...: . .
NP_387 TTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFS---RICCDVFVTLDVMMCTASIL
70 80 90 100 110
120 130 140 150 160
pF1KE0 LLLGVGVTRYLAIAHHRFYAERLAGWPC--AAMLVCAAWALALAAAFPPVLDGGGDDEDA
: .... :: :.. : . . : .:... :.:.::.:.. : .. . . .
NP_387 NLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPT
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE0 PCALEQRPDGA--PGALGFLLLLAVVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDW
:.. . :: . ....: : ..:.: ::: :. ...::. : :. :.
NP_387 VCSI-SNPDFVIYSSVVSFYLPFGVTV----LVYARIYVVLKQRRRKRI--LTRQNSQCN
180 190 200 210 220 230
230 240 250 260 270
pF1KE0 TFHGPGATGQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKT--------E
. . :: :. . : . .::: : . .: :: :
NP_387 SVR-PGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLMPLRE
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE0 KRLCKMFYAVTLLFLLLWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCF
:. .: : :.. : :. .. : . . : .:..:: ......:::.
NP_387 KKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYT
300 310 320 330 340 350
340 350 360 370
pF1KE0 LFNRELRDCFRAQFPCCQSPRTTQATHPCDLKGIGL
:: :.: : . :
NP_387 TFNIEFRKAFLKILSC
360
375 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:45:13 2016 done: Sun Nov 6 17:45:14 2016
Total Scan time: 8.530 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]