Result of FASTA (omim) for
pFN21AE0797
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0797, 1572 aa
1>>>pF1KE0797 1572 - 1572 aa - 1572 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 17.3907+/-0.000535; mu= -30.1095+/- 0.033
mean_var=821.6823+/-168.803, 0's: 0 Z-trim(124.3): 314 B-trim: 0 in 0/61
Lambda= 0.044743
statistics sampled from 45231 (45595) to 45231 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.775), E-opt: 0.2 (0.535), width: 16
Scan time: 21.580
The best scores are: opt bits E(85289)
NP_620614 (OMIM: 600014,601358) probable global tr (1572) 10527 696.2 5.7e-199
NP_003061 (OMIM: 600014,601358) probable global tr (1590) 9415 624.4 2.3e-177
NP_001276325 (OMIM: 600014,601358) probable global (1590) 9415 624.4 2.3e-177
XP_016882657 (OMIM: 603254,613325,614609) PREDICTE (1613) 6400 429.8 9.1e-119
NP_001122320 (OMIM: 603254,613325,614609) transcri (1613) 6400 429.8 9.1e-119
XP_016882656 (OMIM: 603254,613325,614609) PREDICTE (1614) 6364 427.5 4.5e-118
NP_001122319 (OMIM: 603254,613325,614609) transcri (1614) 6364 427.5 4.5e-118
XP_016882655 (OMIM: 603254,613325,614609) PREDICTE (1616) 6320 424.6 3.3e-117
NP_001122318 (OMIM: 603254,613325,614609) transcri (1616) 6320 424.6 3.3e-117
NP_001122317 (OMIM: 603254,613325,614609) transcri (1617) 6313 424.2 4.5e-117
XP_016882654 (OMIM: 603254,613325,614609) PREDICTE (1617) 6313 424.2 4.5e-117
XP_016882653 (OMIM: 603254,613325,614609) PREDICTE (1645) 6217 418.0 3.3e-115
XP_016882651 (OMIM: 603254,613325,614609) PREDICTE (1646) 6217 418.0 3.3e-115
NP_001276326 (OMIM: 600014,601358) probable global (1514) 5900 397.5 4.5e-109
XP_016882652 (OMIM: 603254,613325,614609) PREDICTE (1646) 5584 377.1 6.6e-103
NP_001122316 (OMIM: 603254,613325,614609) transcri (1647) 5584 377.1 6.6e-103
NP_003063 (OMIM: 603254,613325,614609) transcripti (1647) 5584 377.1 6.6e-103
XP_016882650 (OMIM: 603254,613325,614609) PREDICTE (1650) 5584 377.1 6.6e-103
XP_016882649 (OMIM: 603254,613325,614609) PREDICTE (1678) 5584 377.1 6.7e-103
XP_011526500 (OMIM: 603254,613325,614609) PREDICTE (1679) 5584 377.1 6.7e-103
XP_006722908 (OMIM: 603254,613325,614609) PREDICTE (1679) 5584 377.1 6.7e-103
XP_006722909 (OMIM: 603254,613325,614609) PREDICTE (1679) 5584 377.1 6.7e-103
NP_001122321 (OMIM: 603254,613325,614609) transcri (1679) 5584 377.1 6.7e-103
NP_001276327 (OMIM: 600014,601358) probable global ( 248) 1590 118.7 6.2e-26
NP_001276328 (OMIM: 600014,601358) probable global ( 276) 1585 118.4 8.4e-26
NP_001276329 (OMIM: 600014,601358) probable global ( 278) 1585 118.4 8.4e-26
XP_011515862 (OMIM: 189960,214800,608892,612370) P (1621) 1144 90.5 1.2e-16
XP_016869102 (OMIM: 189960,214800,608892,612370) P (2996) 1144 90.7 2e-16
NP_060250 (OMIM: 189960,214800,608892,612370) chro (2997) 1144 90.7 2e-16
XP_011515857 (OMIM: 189960,214800,608892,612370) P (3026) 1144 90.7 2e-16
XP_016869101 (OMIM: 189960,214800,608892,612370) P (3027) 1144 90.7 2e-16
XP_011515856 (OMIM: 189960,214800,608892,612370) P (3027) 1144 90.7 2e-16
XP_011515855 (OMIM: 189960,214800,608892,612370) P (3027) 1144 90.7 2e-16
XP_016879558 (OMIM: 602120) PREDICTED: chromodomai (1888) 1055 84.8 7.4e-15
NP_005843 (OMIM: 602120) chromodomain-helicase-DNA (1966) 1055 84.8 7.7e-15
NP_001005273 (OMIM: 602120) chromodomain-helicase- (2000) 1055 84.8 7.8e-15
XP_006721491 (OMIM: 602120) PREDICTED: chromodomai (2025) 1055 84.8 7.9e-15
XP_016879557 (OMIM: 602120) PREDICTED: chromodomai (2036) 1055 84.8 7.9e-15
XP_016879555 (OMIM: 602120) PREDICTED: chromodomai (2036) 1055 84.8 7.9e-15
XP_016879556 (OMIM: 602120) PREDICTED: chromodomai (2045) 1055 84.8 7.9e-15
XP_016879554 (OMIM: 602120) PREDICTED: chromodomai (2047) 1055 84.8 7.9e-15
XP_016879559 (OMIM: 602120) PREDICTED: chromodomai (2050) 1055 84.8 7.9e-15
XP_016879553 (OMIM: 602120) PREDICTED: chromodomai (2055) 1055 84.8 8e-15
XP_016879552 (OMIM: 602120) PREDICTED: chromodomai (2056) 1055 84.8 8e-15
NP_001005271 (OMIM: 602120) chromodomain-helicase- (2059) 1055 84.8 8e-15
XP_005256486 (OMIM: 602120) PREDICTED: chromodomai (2060) 1055 84.8 8e-15
XP_005256485 (OMIM: 602120) PREDICTED: chromodomai (2080) 1055 84.8 8e-15
XP_016879551 (OMIM: 602120) PREDICTED: chromodomai (2105) 1055 84.8 8.1e-15
XP_016879550 (OMIM: 602120) PREDICTED: chromodomai (2109) 1055 84.8 8.1e-15
XP_006721487 (OMIM: 602120) PREDICTED: chromodomai (2111) 1055 84.8 8.1e-15
>>NP_620614 (OMIM: 600014,601358) probable global transc (1572 aa)
initn: 10527 init1: 10527 opt: 10527 Z-score: 3693.2 bits: 696.2 E(85289): 5.7e-199
Smith-Waterman score: 10527; 100.0% identity (100.0% similar) in 1572 aa overlap (1-1572:1-1572)
10 20 30 40 50 60
pF1KE0 MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 QQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 QQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 AVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 AVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 LENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 LENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 QTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 QTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 ATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 ATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 TNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 ETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 ETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 LLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 LLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 NGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 NGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 PLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHIL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 AKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 AKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 TIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 KVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 KVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPY
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 MFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 IMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 IMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 VVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 VVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 AGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 AGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE0 RREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 RREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDAL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE0 TEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNP
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE0 PKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRN
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE0 HKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 HKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNE
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE0 EEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAKPVVSDFDSDEEQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 EEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAKPVVSDFDSDEEQDE
1510 1520 1530 1540 1550 1560
1570
pF1KE0 REQSEGSGTDDE
::::::::::::
NP_620 REQSEGSGTDDE
1570
>>NP_003061 (OMIM: 600014,601358) probable global transc (1590 aa)
initn: 9415 init1: 9415 opt: 9415 Z-score: 3305.2 bits: 624.4 E(85289): 2.3e-177
Smith-Waterman score: 10481; 98.9% identity (98.9% similar) in 1590 aa overlap (1-1572:1-1590)
10 20 30 40 50 60
pF1KE0 MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 QQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 AVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 LENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 QTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 ATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 TNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 ETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 LLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 NGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 PLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHIL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 AKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 TIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 KVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPY
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 MFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 IMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 VVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 AGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE0 RREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDAL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE0 TEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNP
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420
pF1KE0 PKLTKQMNAIIDTVINYKD------------------SSGRQLSEVFIQLPSRKELPEYY
::::::::::::::::::: :::::::::::::::::::::::
NP_003 PKLTKQMNAIIDTVINYKDRCNVEKVPSNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYY
1390 1400 1410 1420 1430 1440
1430 1440 1450 1460 1470 1480
pF1KE0 ELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFK
1450 1460 1470 1480 1490 1500
1490 1500 1510 1520 1530 1540
pF1KE0 SARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNR
1510 1520 1530 1540 1550 1560
1550 1560 1570
pF1KE0 GKAKPVVSDFDSDEEQDEREQSEGSGTDDE
::::::::::::::::::::::::::::::
NP_003 GKAKPVVSDFDSDEEQDEREQSEGSGTDDE
1570 1580 1590
>>NP_001276325 (OMIM: 600014,601358) probable global tra (1590 aa)
initn: 9415 init1: 9415 opt: 9415 Z-score: 3305.2 bits: 624.4 E(85289): 2.3e-177
Smith-Waterman score: 10481; 98.9% identity (98.9% similar) in 1590 aa overlap (1-1572:1-1590)
10 20 30 40 50 60
pF1KE0 MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 QQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 AVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 LENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 QTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 ATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 TNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 ETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 LLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 NGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 PLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHIL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 AKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 TIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 KVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPY
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 MFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 IMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 VVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 AGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE0 RREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDAL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE0 TEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNP
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420
pF1KE0 PKLTKQMNAIIDTVINYKD------------------SSGRQLSEVFIQLPSRKELPEYY
::::::::::::::::::: :::::::::::::::::::::::
NP_001 PKLTKQMNAIIDTVINYKDRCNVEKVPSNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYY
1390 1400 1410 1420 1430 1440
1430 1440 1450 1460 1470 1480
pF1KE0 ELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFK
1450 1460 1470 1480 1490 1500
1490 1500 1510 1520 1530 1540
pF1KE0 SARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNR
1510 1520 1530 1540 1550 1560
1550 1560 1570
pF1KE0 GKAKPVVSDFDSDEEQDEREQSEGSGTDDE
::::::::::::::::::::::::::::::
NP_001 GKAKPVVSDFDSDEEQDEREQSEGSGTDDE
1570 1580 1590
>>XP_016882657 (OMIM: 603254,613325,614609) PREDICTED: t (1613 aa)
initn: 7066 init1: 4040 opt: 6400 Z-score: 2253.3 bits: 429.8 E(85289): 9.1e-119
Smith-Waterman score: 8141; 76.6% identity (89.0% similar) in 1624 aa overlap (1-1570:1-1613)
10 20 30 40 50
pF1KE0 MSTPTDP-GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPT
:::: : :. :.:::::::::::: .::::::: ::::.::::::::::::..::.::
XP_016 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPIPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 MGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPP-HPGMGPPQSPMDQHSQ
.: .::..:::::::....:.::. .: . ..::: ::: : ::::: ::::::::
XP_016 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 GYMSPHPSPLGAPEHVSSPMSGGGPTP-PQMPPSQPGALIPG-DPQAMSQPNRGPSPFSP
:: :::::. ::.:::. ..::. ::: . :: . : ::::..: ::::.::.
XP_016 GY----PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQ
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 VQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQ----------
:::::::::.::::::::::::. ::.:::::: .::.:::. .
XP_016 NQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGP
180 190 200 210 220 230
230 240 250 260 270
pF1KE0 -----------QQQQQQQQQQQQPQQQPPQPQT----QQQQQPALVNYNRPSGPGPELSG
. .. . . :.. :: :. . : :. : :: . ..
XP_016 GPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAA
240 250 260 270 280 290
280 290 300 310 320
pF1KE0 P-STPQKLPVPAPGGRPSPAPPAAAQPPAAA-VPGPSVPQPA-PGQPSPVLQLQQKQSRI
: :::::: : : :::::::::. ::::. : :.. .:. :.::.:.. :.::::::
XP_016 PTSTPQKLIPPQPTGRPSPAPPAV--PPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRI
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE0 SPIQKPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNF
.:::::.::::::::::::::::::::::::::::::::: :::::::.::::::::::
XP_016 TPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNF
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE0 QRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKH
:::::::::.::::::.::::::.:::::::::.:::::.::::::::::::::::::::
XP_016 QRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKH
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE0 QEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMA
:::::::::::::::::::::.::::::.:::::.:::::::::::.:::::::::::::
XP_016 QEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMA
480 490 500 510 520 530
510 520 530 540 550 560
pF1KE0 EDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEE
:::::::::::::::.:::::::::::::::::.:: .:: ::.::::::....:: :
XP_016 EDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AE
540 550 560 570 580 590
570 580 590 600 610 620
pF1KE0 NAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYE
:::: :.::::::.::.:::::::::: :.:.::.: : .::::.::.::::::::::
XP_016 NAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYE
600 610 620 630 640 650
630 640 650 660 670 680
pF1KE0 VAPRSDSEESDSDYEEEDEEEESSRQET-------EEKILLDPNSEEVSEKDAKQIIETA
:::::::::: :. :::.::::. . :.: . ::.:..::: ::..:::.:
XP_016 VAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENA
660 670 680 690 700 710
690 700 710 720 730 740
pF1KE0 KQDVDDEYSM-QYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYN
::::::::.. : ::: ::::.::::..:::.:::::..::.::.::..::::.:::::
XP_016 KQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYN
720 730 740 750 760 770
750 760 770 780 790 800
pF1KE0 NNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVV
:::::::::::::::::::::::::::::::.:::.::::::::::::.:::::::::::
XP_016 NNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVV
780 790 800 810 820 830
810 820 830 840 850 860
pF1KE0 KISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
:.::::.:: ::..::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
840 850 860 870 880 890
870 880 890 900 910 920
pF1KE0 CKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
XP_016 CKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
900 910 920 930 940 950
930 940 950 960 970 980
pF1KE0 GERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRH
::.::::::::::::::::::::::::::::::::.::::::::::::::::::..::::
XP_016 GEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH
960 970 980 990 1000 1010
990 1000 1010 1020 1030 1040
pF1KE0 MQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVI
:::::.:::::::::::::::.:::::::::::::::::::::::::::.::::...:..
XP_016 MQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIV
1020 1030 1040 1050 1060 1070
1050 1060 1070 1080 1090 1100
pF1KE0 NGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTT
.: .:::::::::::::::::::::::.:::::::::::::::::::.:.: ::::::::
XP_016 QGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTT
1080 1090 1100 1110 1120 1130
1110 1120 1130 1140 1150 1160
pF1KE0 KSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRA
:.:::. ::: ::::::.::::::::::::::::::.::::.::::::::::::::::::
XP_016 KAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRA
1140 1150 1160 1170 1180 1190
1170 1180 1190 1200 1210 1220
pF1KE0 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
1200 1210 1220 1230 1240 1250
1230 1240 1250 1260 1270 1280
pF1KE0 LEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDEL
:::::..:::::::::::.::::::.:::::::::::.:::::.::::::::::::::::
XP_016 LEHEEQDEEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDEL
1260 1270 1280 1290 1300 1310
1290 1300 1310 1320 1330 1340
pF1KE0 PSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEE
::::::::::::::::::::::.::::::.:..:::::.:::::::.:::.:.:::.:::
XP_016 PSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEE
1320 1330 1340 1350 1360 1370
1350 1360 1370 1380
pF1KE0 VRLKKRKRRRNVDKD-----PA-------KEDVEKAKKRRGRPPAEKLSPNPPKLTKQMN
:: :: .:.:. :.: :. :.: : .:.::::::::::::::.:::.:.
XP_016 VRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMK
1380 1390 1400 1410 1420 1430
1390 1400 1410 1420 1430 1440
pF1KE0 AIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGD
:.:.::.::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_016 KIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLND
1440 1450 1460 1470 1480 1490
1450 1460 1470 1480 1490 1500
pF1KE0 LEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDEE
:::::::::.:::::::::: :::::::::::: :.:::: ::..:: : .::::: .::
XP_016 LEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEE
1500 1510 1520 1530 1540 1550
1510 1520 1530 1540 1550 1560
pF1KE0 ESESEAKSVKVKIKLNKKDDKGRDKGKG-KKRPNRG-KAKPVVSDFDSDEEQDEREQSEG
::::..::::::::..:. :..:. :: ..::.:: .::::::: ::.:::.: ... :
XP_016 GSESESRSVKVKIKLGRKE-KAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSG
1560 1570 1580 1590 1600
1570
pF1KE0 SGTDDE
: :
XP_016 SEED
1610
>>NP_001122320 (OMIM: 603254,613325,614609) transcriptio (1613 aa)
initn: 7066 init1: 4040 opt: 6400 Z-score: 2253.3 bits: 429.8 E(85289): 9.1e-119
Smith-Waterman score: 8141; 76.6% identity (89.0% similar) in 1624 aa overlap (1-1570:1-1613)
10 20 30 40 50
pF1KE0 MSTPTDP-GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPT
:::: : :. :.:::::::::::: .::::::: ::::.::::::::::::..::.::
NP_001 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPIPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 MGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPP-HPGMGPPQSPMDQHSQ
.: .::..:::::::....:.::. .: . ..::: ::: : ::::: ::::::::
NP_001 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 GYMSPHPSPLGAPEHVSSPMSGGGPTP-PQMPPSQPGALIPG-DPQAMSQPNRGPSPFSP
:: :::::. ::.:::. ..::. ::: . :: . : ::::..: ::::.::.
NP_001 GY----PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQ
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 VQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQ----------
:::::::::.::::::::::::. ::.:::::: .::.:::. .
NP_001 NQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGP
180 190 200 210 220 230
230 240 250 260 270
pF1KE0 -----------QQQQQQQQQQQQPQQQPPQPQT----QQQQQPALVNYNRPSGPGPELSG
. .. . . :.. :: :. . : :. : :: . ..
NP_001 GPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAA
240 250 260 270 280 290
280 290 300 310 320
pF1KE0 P-STPQKLPVPAPGGRPSPAPPAAAQPPAAA-VPGPSVPQPA-PGQPSPVLQLQQKQSRI
: :::::: : : :::::::::. ::::. : :.. .:. :.::.:.. :.::::::
NP_001 PTSTPQKLIPPQPTGRPSPAPPAV--PPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRI
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE0 SPIQKPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNF
.:::::.::::::::::::::::::::::::::::::::: :::::::.::::::::::
NP_001 TPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNF
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE0 QRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKH
:::::::::.::::::.::::::.:::::::::.:::::.::::::::::::::::::::
NP_001 QRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKH
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE0 QEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMA
:::::::::::::::::::::.::::::.:::::.:::::::::::.:::::::::::::
NP_001 QEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMA
480 490 500 510 520 530
510 520 530 540 550 560
pF1KE0 EDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEE
:::::::::::::::.:::::::::::::::::.:: .:: ::.::::::....:: :
NP_001 EDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AE
540 550 560 570 580 590
570 580 590 600 610 620
pF1KE0 NAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYE
:::: :.::::::.::.:::::::::: :.:.::.: : .::::.::.::::::::::
NP_001 NAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYE
600 610 620 630 640 650
630 640 650 660 670 680
pF1KE0 VAPRSDSEESDSDYEEEDEEEESSRQET-------EEKILLDPNSEEVSEKDAKQIIETA
:::::::::: :. :::.::::. . :.: . ::.:..::: ::..:::.:
NP_001 VAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENA
660 670 680 690 700 710
690 700 710 720 730 740
pF1KE0 KQDVDDEYSM-QYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYN
::::::::.. : ::: ::::.::::..:::.:::::..::.::.::..::::.:::::
NP_001 KQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYN
720 730 740 750 760 770
750 760 770 780 790 800
pF1KE0 NNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVV
:::::::::::::::::::::::::::::::.:::.::::::::::::.:::::::::::
NP_001 NNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVV
780 790 800 810 820 830
810 820 830 840 850 860
pF1KE0 KISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
:.::::.:: ::..::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
840 850 860 870 880 890
870 880 890 900 910 920
pF1KE0 CKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
NP_001 CKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
900 910 920 930 940 950
930 940 950 960 970 980
pF1KE0 GERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRH
::.::::::::::::::::::::::::::::::::.::::::::::::::::::..::::
NP_001 GEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH
960 970 980 990 1000 1010
990 1000 1010 1020 1030 1040
pF1KE0 MQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVI
:::::.:::::::::::::::.:::::::::::::::::::::::::::.::::...:..
NP_001 MQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIV
1020 1030 1040 1050 1060 1070
1050 1060 1070 1080 1090 1100
pF1KE0 NGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTT
.: .:::::::::::::::::::::::.:::::::::::::::::::.:.: ::::::::
NP_001 QGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTT
1080 1090 1100 1110 1120 1130
1110 1120 1130 1140 1150 1160
pF1KE0 KSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRA
:.:::. ::: ::::::.::::::::::::::::::.::::.::::::::::::::::::
NP_001 KAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRA
1140 1150 1160 1170 1180 1190
1170 1180 1190 1200 1210 1220
pF1KE0 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
1200 1210 1220 1230 1240 1250
1230 1240 1250 1260 1270 1280
pF1KE0 LEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDEL
:::::..:::::::::::.::::::.:::::::::::.:::::.::::::::::::::::
NP_001 LEHEEQDEEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDEL
1260 1270 1280 1290 1300 1310
1290 1300 1310 1320 1330 1340
pF1KE0 PSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEE
::::::::::::::::::::::.::::::.:..:::::.:::::::.:::.:.:::.:::
NP_001 PSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEE
1320 1330 1340 1350 1360 1370
1350 1360 1370 1380
pF1KE0 VRLKKRKRRRNVDKD-----PA-------KEDVEKAKKRRGRPPAEKLSPNPPKLTKQMN
:: :: .:.:. :.: :. :.: : .:.::::::::::::::.:::.:.
NP_001 VRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMK
1380 1390 1400 1410 1420 1430
1390 1400 1410 1420 1430 1440
pF1KE0 AIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGD
:.:.::.::::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_001 KIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLND
1440 1450 1460 1470 1480 1490
1450 1460 1470 1480 1490 1500
pF1KE0 LEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDEE
:::::::::.:::::::::: :::::::::::: :.:::: ::..:: : .::::: .::
NP_001 LEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEE
1500 1510 1520 1530 1540 1550
1510 1520 1530 1540 1550 1560
pF1KE0 ESESEAKSVKVKIKLNKKDDKGRDKGKG-KKRPNRG-KAKPVVSDFDSDEEQDEREQSEG
::::..::::::::..:. :..:. :: ..::.:: .::::::: ::.:::.: ... :
NP_001 GSESESRSVKVKIKLGRKE-KAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSG
1560 1570 1580 1590 1600
1570
pF1KE0 SGTDDE
: :
NP_001 SEED
1610
>>XP_016882656 (OMIM: 603254,613325,614609) PREDICTED: t (1614 aa)
initn: 6900 init1: 4045 opt: 6364 Z-score: 2240.7 bits: 427.5 E(85289): 4.5e-118
Smith-Waterman score: 8129; 76.6% identity (88.9% similar) in 1625 aa overlap (1-1570:1-1614)
10 20 30 40 50
pF1KE0 MSTPTDP-GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPT
:::: : :. :.:::::::::::: .::::::: ::::.::::::::::::..::.::
XP_016 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPIPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 MGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPP-HPGMGPPQSPMDQHSQ
.: .::..:::::::....:.::. .: . ..::: ::: : ::::: ::::::::
XP_016 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 GYMSPHPSPLGAPEHVSSPMSGGGPTP-PQMPPSQPGALIPG-DPQAMSQPNRGPSPFSP
:: :::::. ::.:::. ..::. ::: . :: . : ::::..: ::::.::.
XP_016 GY----PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQ
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 VQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQ----------
:::::::::.::::::::::::. ::.:::::: .::.:::. .
XP_016 NQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGP
180 190 200 210 220 230
230 240 250 260 270
pF1KE0 -----------QQQQQQQQQQQQPQQQPPQPQT----QQQQQPALVNYNRPSGPGPELSG
. .. . . :.. :: :. . : :. : :: . ..
XP_016 GPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAA
240 250 260 270 280 290
280 290 300 310 320
pF1KE0 P-STPQKLPVPAPGGRPSPAPPAAAQPPAAA-VPGPSVPQPA-PGQPSPVLQLQQKQSRI
: :::::: : : :::::::::. ::::. : :.. .:. :.::.:.. :.::::::
XP_016 PTSTPQKLIPPQPTGRPSPAPPAV--PPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRI
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE0 SPIQKPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNF
.:::::.::::::::::::::::::::::::::::::::: :::::::.::::::::::
XP_016 TPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNF
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE0 QRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKH
:::::::::.::::::.::::::.:::::::::.:::::.::::::::::::::::::::
XP_016 QRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKH
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE0 QEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMA
:::::::::::::::::::::.::::::.:::::.:::::::::::.:::::::::::::
XP_016 QEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMA
480 490 500 510 520 530
510 520 530 540 550 560
pF1KE0 EDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEE
:::::::::::::::.:::::::::::::::::.:: .:: ::.::::::....:: :
XP_016 EDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AE
540 550 560 570 580 590
570 580 590 600 610 620
pF1KE0 NAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYE
:::: :.::::::.::.:::::::::: :.:.::.: : .::::.::.::::::::::
XP_016 NAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYE
600 610 620 630 640 650
630 640 650 660 670 680
pF1KE0 VAPRSDSEESDSDYEEEDEEEESSRQET-------EEKILLDPNSEEVSEKDAKQIIETA
:::::::::: :. :::.::::. . :.: . ::.:..::: ::..:::.:
XP_016 VAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENA
660 670 680 690 700 710
690 700 710 720 730 740
pF1KE0 KQDVDDEYSM-QYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYN
::::::::.. : ::: ::::.::::..:::.:::::..::.::.::..::::.:::::
XP_016 KQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYN
720 730 740 750 760 770
750 760 770 780 790 800
pF1KE0 NNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVV
:::::::::::::::::::::::::::::::.:::.::::::::::::.:::::::::::
XP_016 NNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVV
780 790 800 810 820 830
810 820 830 840 850 860
pF1KE0 KISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
:.::::.:: ::..::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
840 850 860 870 880 890
870 880 890 900 910 920
pF1KE0 CKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
XP_016 CKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
900 910 920 930 940 950
930 940 950 960 970 980
pF1KE0 GERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRH
::.::::::::::::::::::::::::::::::::.::::::::::::::::::..::::
XP_016 GEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH
960 970 980 990 1000 1010
990 1000 1010 1020 1030 1040
pF1KE0 MQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVI
:::::.:::::::::::::::.:::::::::::::::::::::::::::.::::...:..
XP_016 MQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIV
1020 1030 1040 1050 1060 1070
1050 1060 1070 1080 1090 1100
pF1KE0 NGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTT
.: .:::::::::::::::::::::::.:::::::::::::::::::.:.: ::::::::
XP_016 QGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTT
1080 1090 1100 1110 1120 1130
1110 1120 1130 1140 1150 1160
pF1KE0 KSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRA
:.:::. ::: ::::::.::::::::::::::::::.::::.::::::::::::::::::
XP_016 KAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRA
1140 1150 1160 1170 1180 1190
1170 1180 1190 1200 1210 1220
pF1KE0 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
1200 1210 1220 1230 1240 1250
1230 1240 1250 1260 1270 1280
pF1KE0 LEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDEL
:::::..:::::::::::.::::::.:::::::::::.:::::.::::::::::::::::
XP_016 LEHEEQDEEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDEL
1260 1270 1280 1290 1300 1310
1290 1300 1310 1320 1330 1340
pF1KE0 PSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEE
::::::::::::::::::::::.::::::.:..:::::.:::::::.:::.:.:::.:::
XP_016 PSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEE
1320 1330 1340 1350 1360 1370
1350 1360 1370 1380
pF1KE0 VRLKKRKRRRNVDKD-----PA-------KEDVEKAKKRRGRPPAEKLSPNPPKLTKQMN
:: :: .:.:. :.: :. :.: : .:.::::::::::::::.:::.:.
XP_016 VRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMK
1380 1390 1400 1410 1420 1430
1390 1400 1410 1420 1430 1440
pF1KE0 AIIDTVINYKDSS-GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLG
:.:.::.::::: :::::::::::::::::::::::::::::::::::::::::::::.
XP_016 KIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLN
1440 1450 1460 1470 1480 1490
1450 1460 1470 1480 1490 1500
pF1KE0 DLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDE
::::::::::.:::::::::: :::::::::::: :.:::: ::..:: : .::::: .:
XP_016 DLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEE
1500 1510 1520 1530 1540 1550
1510 1520 1530 1540 1550 1560
pF1KE0 EESESEAKSVKVKIKLNKKDDKGRDKGKG-KKRPNRG-KAKPVVSDFDSDEEQDEREQSE
: ::::..::::::::..:. :..:. :: ..::.:: .::::::: ::.:::.: ...
XP_016 EGSESESRSVKVKIKLGRKE-KAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGS
1560 1570 1580 1590 1600
1570
pF1KE0 GSGTDDE
:: :
XP_016 GSEED
1610
>>NP_001122319 (OMIM: 603254,613325,614609) transcriptio (1614 aa)
initn: 6900 init1: 4045 opt: 6364 Z-score: 2240.7 bits: 427.5 E(85289): 4.5e-118
Smith-Waterman score: 8129; 76.6% identity (88.9% similar) in 1625 aa overlap (1-1570:1-1614)
10 20 30 40 50
pF1KE0 MSTPTDP-GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPT
:::: : :. :.:::::::::::: .::::::: ::::.::::::::::::..::.::
NP_001 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPIPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 MGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPP-HPGMGPPQSPMDQHSQ
.: .::..:::::::....:.::. .: . ..::: ::: : ::::: ::::::::
NP_001 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 GYMSPHPSPLGAPEHVSSPMSGGGPTP-PQMPPSQPGALIPG-DPQAMSQPNRGPSPFSP
:: :::::. ::.:::. ..::. ::: . :: . : ::::..: ::::.::.
NP_001 GY----PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQ
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 VQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQ----------
:::::::::.::::::::::::. ::.:::::: .::.:::. .
NP_001 NQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGP
180 190 200 210 220 230
230 240 250 260 270
pF1KE0 -----------QQQQQQQQQQQQPQQQPPQPQT----QQQQQPALVNYNRPSGPGPELSG
. .. . . :.. :: :. . : :. : :: . ..
NP_001 GPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAA
240 250 260 270 280 290
280 290 300 310 320
pF1KE0 P-STPQKLPVPAPGGRPSPAPPAAAQPPAAA-VPGPSVPQPA-PGQPSPVLQLQQKQSRI
: :::::: : : :::::::::. ::::. : :.. .:. :.::.:.. :.::::::
NP_001 PTSTPQKLIPPQPTGRPSPAPPAV--PPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRI
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE0 SPIQKPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNF
.:::::.::::::::::::::::::::::::::::::::: :::::::.::::::::::
NP_001 TPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNF
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE0 QRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKH
:::::::::.::::::.::::::.:::::::::.:::::.::::::::::::::::::::
NP_001 QRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKH
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE0 QEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMA
:::::::::::::::::::::.::::::.:::::.:::::::::::.:::::::::::::
NP_001 QEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMA
480 490 500 510 520 530
510 520 530 540 550 560
pF1KE0 EDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEE
:::::::::::::::.:::::::::::::::::.:: .:: ::.::::::....:: :
NP_001 EDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AE
540 550 560 570 580 590
570 580 590 600 610 620
pF1KE0 NAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYE
:::: :.::::::.::.:::::::::: :.:.::.: : .::::.::.::::::::::
NP_001 NAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYE
600 610 620 630 640 650
630 640 650 660 670 680
pF1KE0 VAPRSDSEESDSDYEEEDEEEESSRQET-------EEKILLDPNSEEVSEKDAKQIIETA
:::::::::: :. :::.::::. . :.: . ::.:..::: ::..:::.:
NP_001 VAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENA
660 670 680 690 700 710
690 700 710 720 730 740
pF1KE0 KQDVDDEYSM-QYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYN
::::::::.. : ::: ::::.::::..:::.:::::..::.::.::..::::.:::::
NP_001 KQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYN
720 730 740 750 760 770
750 760 770 780 790 800
pF1KE0 NNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVV
:::::::::::::::::::::::::::::::.:::.::::::::::::.:::::::::::
NP_001 NNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVV
780 790 800 810 820 830
810 820 830 840 850 860
pF1KE0 KISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
:.::::.:: ::..::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
840 850 860 870 880 890
870 880 890 900 910 920
pF1KE0 CKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
NP_001 CKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
900 910 920 930 940 950
930 940 950 960 970 980
pF1KE0 GERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRH
::.::::::::::::::::::::::::::::::::.::::::::::::::::::..::::
NP_001 GEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH
960 970 980 990 1000 1010
990 1000 1010 1020 1030 1040
pF1KE0 MQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVI
:::::.:::::::::::::::.:::::::::::::::::::::::::::.::::...:..
NP_001 MQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIV
1020 1030 1040 1050 1060 1070
1050 1060 1070 1080 1090 1100
pF1KE0 NGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTT
.: .:::::::::::::::::::::::.:::::::::::::::::::.:.: ::::::::
NP_001 QGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTT
1080 1090 1100 1110 1120 1130
1110 1120 1130 1140 1150 1160
pF1KE0 KSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRA
:.:::. ::: ::::::.::::::::::::::::::.::::.::::::::::::::::::
NP_001 KAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRA
1140 1150 1160 1170 1180 1190
1170 1180 1190 1200 1210 1220
pF1KE0 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
1200 1210 1220 1230 1240 1250
1230 1240 1250 1260 1270 1280
pF1KE0 LEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDEL
:::::..:::::::::::.::::::.:::::::::::.:::::.::::::::::::::::
NP_001 LEHEEQDEEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDEL
1260 1270 1280 1290 1300 1310
1290 1300 1310 1320 1330 1340
pF1KE0 PSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEE
::::::::::::::::::::::.::::::.:..:::::.:::::::.:::.:.:::.:::
NP_001 PSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEE
1320 1330 1340 1350 1360 1370
1350 1360 1370 1380
pF1KE0 VRLKKRKRRRNVDKD-----PA-------KEDVEKAKKRRGRPPAEKLSPNPPKLTKQMN
:: :: .:.:. :.: :. :.: : .:.::::::::::::::.:::.:.
NP_001 VRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMK
1380 1390 1400 1410 1420 1430
1390 1400 1410 1420 1430 1440
pF1KE0 AIIDTVINYKDSS-GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLG
:.:.::.::::: :::::::::::::::::::::::::::::::::::::::::::::.
NP_001 KIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLN
1440 1450 1460 1470 1480 1490
1450 1460 1470 1480 1490 1500
pF1KE0 DLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDE
::::::::::.:::::::::: :::::::::::: :.:::: ::..:: : .::::: .:
NP_001 DLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEE
1500 1510 1520 1530 1540 1550
1510 1520 1530 1540 1550 1560
pF1KE0 EESESEAKSVKVKIKLNKKDDKGRDKGKG-KKRPNRG-KAKPVVSDFDSDEEQDEREQSE
: ::::..::::::::..:. :..:. :: ..::.:: .::::::: ::.:::.: ...
NP_001 EGSESESRSVKVKIKLGRKE-KAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGS
1560 1570 1580 1590 1600
1570
pF1KE0 GSGTDDE
:: :
NP_001 GSEED
1610
>>XP_016882655 (OMIM: 603254,613325,614609) PREDICTED: t (1616 aa)
initn: 6957 init1: 3931 opt: 6320 Z-score: 2225.3 bits: 424.6 E(85289): 3.3e-117
Smith-Waterman score: 8125; 76.5% identity (88.8% similar) in 1627 aa overlap (1-1570:1-1616)
10 20 30 40 50
pF1KE0 MSTPTDP-GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPT
:::: : :. :.:::::::::::: .::::::: ::::.::::::::::::..::.::
XP_016 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPIPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 MGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPP-HPGMGPPQSPMDQHSQ
.: .::..:::::::....:.::. .: . ..::: ::: : ::::: ::::::::
XP_016 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 GYMSPHPSPLGAPEHVSSPMSGGGPTP-PQMPPSQPGALIPG-DPQAMSQPNRGPSPFSP
:: :::::. ::.:::. ..::. ::: . :: . : ::::..: ::::.::.
XP_016 GY----PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQ
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 VQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQ----------
:::::::::.::::::::::::. ::.:::::: .::.:::. .
XP_016 NQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGP
180 190 200 210 220 230
230 240 250 260 270
pF1KE0 -----------QQQQQQQQQQQQPQQQPPQPQT----QQQQQPALVNYNRPSGPGPELSG
. .. . . :.. :: :. . : :. : :: . ..
XP_016 GPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAA
240 250 260 270 280 290
280 290 300 310 320
pF1KE0 P-STPQKLPVPAPGGRPSPAPPAAAQPPAAA-VPGPSVPQPA-PGQPSPVLQLQQKQSRI
: :::::: : : :::::::::. ::::. : :.. .:. :.::.:.. :.::::::
XP_016 PTSTPQKLIPPQPTGRPSPAPPAV--PPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRI
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE0 SPIQKPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNF
.:::::.::::::::::::::::::::::::::::::::: :::::::.::::::::::
XP_016 TPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNF
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE0 QRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKH
:::::::::.::::::.::::::.:::::::::.:::::.::::::::::::::::::::
XP_016 QRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKH
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE0 QEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMA
:::::::::::::::::::::.::::::.:::::.:::::::::::.:::::::::::::
XP_016 QEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMA
480 490 500 510 520 530
510 520 530 540 550 560
pF1KE0 EDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEE
:::::::::::::::.:::::::::::::::::.:: .:: ::.::::::....:: :
XP_016 EDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AE
540 550 560 570 580 590
570 580 590 600 610 620
pF1KE0 NAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYE
:::: :.::::::.::.:::::::::: :.:.::.: : .::::.::.::::::::::
XP_016 NAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYE
600 610 620 630 640 650
630 640 650 660 670 680
pF1KE0 VAPRSDSEESDSDYEEEDEEEESSRQET-------EEKILLDPNSEEVSEKDAKQIIETA
:::::::::: :. :::.::::. . :.: . ::.:..::: ::..:::.:
XP_016 VAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENA
660 670 680 690 700 710
690 700 710 720 730 740
pF1KE0 KQDVDDEYSM-QYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYN
::::::::.. : ::: ::::.::::..:::.:::::..::.::.::..::::.:::::
XP_016 KQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYN
720 730 740 750 760 770
750 760 770 780 790 800
pF1KE0 NNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVV
:::::::::::::::::::::::::::::::.:::.::::::::::::.:::::::::::
XP_016 NNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVV
780 790 800 810 820 830
810 820 830 840 850 860
pF1KE0 KISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
:.::::.:: ::..::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
840 850 860 870 880 890
870 880 890 900 910 920
pF1KE0 CKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
XP_016 CKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
900 910 920 930 940 950
930 940 950 960 970 980
pF1KE0 GERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRH
::.::::::::::::::::::::::::::::::::.::::::::::::::::::..::::
XP_016 GEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH
960 970 980 990 1000 1010
990 1000 1010 1020 1030 1040
pF1KE0 MQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVI
:::::.:::::::::::::::.:::::::::::::::::::::::::::.::::...:..
XP_016 MQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIV
1020 1030 1040 1050 1060 1070
1050 1060 1070 1080 1090 1100
pF1KE0 NGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTT
.: .:::::::::::::::::::::::.:::::::::::::::::::.:.: ::::::::
XP_016 QGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTT
1080 1090 1100 1110 1120 1130
1110 1120 1130 1140 1150 1160
pF1KE0 KSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRA
:.:::. ::: ::::::.::::::::::::::::::.::::.::::::::::::::::::
XP_016 KAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRA
1140 1150 1160 1170 1180 1190
1170 1180 1190 1200 1210 1220
pF1KE0 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
1200 1210 1220 1230 1240 1250
1230 1240 1250 1260 1270 1280
pF1KE0 LEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDEL
:::::..:::::::::::.::::::.:::::::::::.:::::.::::::::::::::::
XP_016 LEHEEQDEEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDEL
1260 1270 1280 1290 1300 1310
1290 1300 1310 1320 1330
pF1KE0 PSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLR---AIEDGNLEEM
::::::::::::::::::::::.::::::.:..:::::.:::::::. :::.:.:::.
XP_016 PSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKTLKAIEEGTLEEI
1320 1330 1340 1350 1360 1370
1340 1350 1360 1370 1380
pF1KE0 EEEVRLKKRKRRRNVDKD-----PA-------KEDVEKAKKRRGRPPAEKLSPNPPKLTK
::::: :: .:.:. :.: :. :.: : .:.::::::::::::::.:::
XP_016 EEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK
1380 1390 1400 1410 1420 1430
1390 1400 1410 1420 1430 1440
pF1KE0 QMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRS
.:. :.:.::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMKKIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRS
1440 1450 1460 1470 1480 1490
1450 1460 1470 1480 1490 1500
pF1KE0 LGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEE
:.::::::::::.:::::::::: :::::::::::: :.:::: ::..:: : .:::::
XP_016 LNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEG
1500 1510 1520 1530 1540 1550
1510 1520 1530 1540 1550 1560
pF1KE0 DEEESESEAKSVKVKIKLNKKDDKGRDKGKG-KKRPNRG-KAKPVVSDFDSDEEQDEREQ
.:: ::::..::::::::..:. :..:. :: ..::.:: .::::::: ::.:::.: ..
XP_016 EEEGSESESRSVKVKIKLGRKE-KAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRS
1560 1570 1580 1590 1600
1570
pF1KE0 SEGSGTDDE
. :: :
XP_016 GSGSEED
1610
>>NP_001122318 (OMIM: 603254,613325,614609) transcriptio (1616 aa)
initn: 6957 init1: 3931 opt: 6320 Z-score: 2225.3 bits: 424.6 E(85289): 3.3e-117
Smith-Waterman score: 8125; 76.5% identity (88.8% similar) in 1627 aa overlap (1-1570:1-1616)
10 20 30 40 50
pF1KE0 MSTPTDP-GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPT
:::: : :. :.:::::::::::: .::::::: ::::.::::::::::::..::.::
NP_001 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPIPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 MGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPP-HPGMGPPQSPMDQHSQ
.: .::..:::::::....:.::. .: . ..::: ::: : ::::: ::::::::
NP_001 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 GYMSPHPSPLGAPEHVSSPMSGGGPTP-PQMPPSQPGALIPG-DPQAMSQPNRGPSPFSP
:: :::::. ::.:::. ..::. ::: . :: . : ::::..: ::::.::.
NP_001 GY----PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQ
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 VQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQ----------
:::::::::.::::::::::::. ::.:::::: .::.:::. .
NP_001 NQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGP
180 190 200 210 220 230
230 240 250 260 270
pF1KE0 -----------QQQQQQQQQQQQPQQQPPQPQT----QQQQQPALVNYNRPSGPGPELSG
. .. . . :.. :: :. . : :. : :: . ..
NP_001 GPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAA
240 250 260 270 280 290
280 290 300 310 320
pF1KE0 P-STPQKLPVPAPGGRPSPAPPAAAQPPAAA-VPGPSVPQPA-PGQPSPVLQLQQKQSRI
: :::::: : : :::::::::. ::::. : :.. .:. :.::.:.. :.::::::
NP_001 PTSTPQKLIPPQPTGRPSPAPPAV--PPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRI
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE0 SPIQKPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNF
.:::::.::::::::::::::::::::::::::::::::: :::::::.::::::::::
NP_001 TPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNF
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE0 QRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKH
:::::::::.::::::.::::::.:::::::::.:::::.::::::::::::::::::::
NP_001 QRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKH
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE0 QEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMA
:::::::::::::::::::::.::::::.:::::.:::::::::::.:::::::::::::
NP_001 QEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMA
480 490 500 510 520 530
510 520 530 540 550 560
pF1KE0 EDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEE
:::::::::::::::.:::::::::::::::::.:: .:: ::.::::::....:: :
NP_001 EDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AE
540 550 560 570 580 590
570 580 590 600 610 620
pF1KE0 NAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYE
:::: :.::::::.::.:::::::::: :.:.::.: : .::::.::.::::::::::
NP_001 NAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYE
600 610 620 630 640 650
630 640 650 660 670 680
pF1KE0 VAPRSDSEESDSDYEEEDEEEESSRQET-------EEKILLDPNSEEVSEKDAKQIIETA
:::::::::: :. :::.::::. . :.: . ::.:..::: ::..:::.:
NP_001 VAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENA
660 670 680 690 700 710
690 700 710 720 730 740
pF1KE0 KQDVDDEYSM-QYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYN
::::::::.. : ::: ::::.::::..:::.:::::..::.::.::..::::.:::::
NP_001 KQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYN
720 730 740 750 760 770
750 760 770 780 790 800
pF1KE0 NNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVV
:::::::::::::::::::::::::::::::.:::.::::::::::::.:::::::::::
NP_001 NNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVV
780 790 800 810 820 830
810 820 830 840 850 860
pF1KE0 KISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
:.::::.:: ::..::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
840 850 860 870 880 890
870 880 890 900 910 920
pF1KE0 CKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
NP_001 CKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
900 910 920 930 940 950
930 940 950 960 970 980
pF1KE0 GERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRH
::.::::::::::::::::::::::::::::::::.::::::::::::::::::..::::
NP_001 GEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH
960 970 980 990 1000 1010
990 1000 1010 1020 1030 1040
pF1KE0 MQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVI
:::::.:::::::::::::::.:::::::::::::::::::::::::::.::::...:..
NP_001 MQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIV
1020 1030 1040 1050 1060 1070
1050 1060 1070 1080 1090 1100
pF1KE0 NGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTT
.: .:::::::::::::::::::::::.:::::::::::::::::::.:.: ::::::::
NP_001 QGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTT
1080 1090 1100 1110 1120 1130
1110 1120 1130 1140 1150 1160
pF1KE0 KSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRA
:.:::. ::: ::::::.::::::::::::::::::.::::.::::::::::::::::::
NP_001 KAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRA
1140 1150 1160 1170 1180 1190
1170 1180 1190 1200 1210 1220
pF1KE0 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
1200 1210 1220 1230 1240 1250
1230 1240 1250 1260 1270 1280
pF1KE0 LEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDEL
:::::..:::::::::::.::::::.:::::::::::.:::::.::::::::::::::::
NP_001 LEHEEQDEEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDEL
1260 1270 1280 1290 1300 1310
1290 1300 1310 1320 1330
pF1KE0 PSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLR---AIEDGNLEEM
::::::::::::::::::::::.::::::.:..:::::.:::::::. :::.:.:::.
NP_001 PSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKTLKAIEEGTLEEI
1320 1330 1340 1350 1360 1370
1340 1350 1360 1370 1380
pF1KE0 EEEVRLKKRKRRRNVDKD-----PA-------KEDVEKAKKRRGRPPAEKLSPNPPKLTK
::::: :: .:.:. :.: :. :.: : .:.::::::::::::::.:::
NP_001 EEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK
1380 1390 1400 1410 1420 1430
1390 1400 1410 1420 1430 1440
pF1KE0 QMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRS
.:. :.:.::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMKKIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRS
1440 1450 1460 1470 1480 1490
1450 1460 1470 1480 1490 1500
pF1KE0 LGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEE
:.::::::::::.:::::::::: :::::::::::: :.:::: ::..:: : .:::::
NP_001 LNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEG
1500 1510 1520 1530 1540 1550
1510 1520 1530 1540 1550 1560
pF1KE0 DEEESESEAKSVKVKIKLNKKDDKGRDKGKG-KKRPNRG-KAKPVVSDFDSDEEQDEREQ
.:: ::::..::::::::..:. :..:. :: ..::.:: .::::::: ::.:::.: ..
NP_001 EEEGSESESRSVKVKIKLGRKE-KAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRS
1560 1570 1580 1590 1600
1570
pF1KE0 SEGSGTDDE
. :: :
NP_001 GSGSEED
1610
>>NP_001122317 (OMIM: 603254,613325,614609) transcriptio (1617 aa)
initn: 6989 init1: 3931 opt: 6313 Z-score: 2222.9 bits: 424.2 E(85289): 4.5e-117
Smith-Waterman score: 8113; 76.4% identity (88.8% similar) in 1628 aa overlap (1-1570:1-1617)
10 20 30 40 50
pF1KE0 MSTPTDP-GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPT
:::: : :. :.:::::::::::: .::::::: ::::.::::::::::::..::.::
NP_001 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPIPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 MGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPP-HPGMGPPQSPMDQHSQ
.: .::..:::::::....:.::. .: . ..::: ::: : ::::: ::::::::
NP_001 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 GYMSPHPSPLGAPEHVSSPMSGGGPTP-PQMPPSQPGALIPG-DPQAMSQPNRGPSPFSP
:: :::::. ::.:::. ..::. ::: . :: . : ::::..: ::::.::.
NP_001 GY----PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQ
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 VQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQ----------
:::::::::.::::::::::::. ::.:::::: .::.:::. .
NP_001 NQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGP
180 190 200 210 220 230
230 240 250 260 270
pF1KE0 -----------QQQQQQQQQQQQPQQQPPQPQT----QQQQQPALVNYNRPSGPGPELSG
. .. . . :.. :: :. . : :. : :: . ..
NP_001 GPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAA
240 250 260 270 280 290
280 290 300 310 320
pF1KE0 P-STPQKLPVPAPGGRPSPAPPAAAQPPAAA-VPGPSVPQPA-PGQPSPVLQLQQKQSRI
: :::::: : : :::::::::. ::::. : :.. .:. :.::.:.. :.::::::
NP_001 PTSTPQKLIPPQPTGRPSPAPPAV--PPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRI
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE0 SPIQKPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNF
.:::::.::::::::::::::::::::::::::::::::: :::::::.::::::::::
NP_001 TPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNF
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE0 QRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKH
:::::::::.::::::.::::::.:::::::::.:::::.::::::::::::::::::::
NP_001 QRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKH
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE0 QEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMA
:::::::::::::::::::::.::::::.:::::.:::::::::::.:::::::::::::
NP_001 QEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMA
480 490 500 510 520 530
510 520 530 540 550 560
pF1KE0 EDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEE
:::::::::::::::.:::::::::::::::::.:: .:: ::.::::::....:: :
NP_001 EDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AE
540 550 560 570 580 590
570 580 590 600 610 620
pF1KE0 NAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYE
:::: :.::::::.::.:::::::::: :.:.::.: : .::::.::.::::::::::
NP_001 NAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYE
600 610 620 630 640 650
630 640 650 660 670 680
pF1KE0 VAPRSDSEESDSDYEEEDEEEESSRQET-------EEKILLDPNSEEVSEKDAKQIIETA
:::::::::: :. :::.::::. . :.: . ::.:..::: ::..:::.:
NP_001 VAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENA
660 670 680 690 700 710
690 700 710 720 730 740
pF1KE0 KQDVDDEYSM-QYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYN
::::::::.. : ::: ::::.::::..:::.:::::..::.::.::..::::.:::::
NP_001 KQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYN
720 730 740 750 760 770
750 760 770 780 790 800
pF1KE0 NNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVV
:::::::::::::::::::::::::::::::.:::.::::::::::::.:::::::::::
NP_001 NNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVV
780 790 800 810 820 830
810 820 830 840 850 860
pF1KE0 KISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
:.::::.:: ::..::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
840 850 860 870 880 890
870 880 890 900 910 920
pF1KE0 CKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
NP_001 CKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
900 910 920 930 940 950
930 940 950 960 970 980
pF1KE0 GERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRH
::.::::::::::::::::::::::::::::::::.::::::::::::::::::..::::
NP_001 GEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH
960 970 980 990 1000 1010
990 1000 1010 1020 1030 1040
pF1KE0 MQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVI
:::::.:::::::::::::::.:::::::::::::::::::::::::::.::::...:..
NP_001 MQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIV
1020 1030 1040 1050 1060 1070
1050 1060 1070 1080 1090 1100
pF1KE0 NGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTT
.: .:::::::::::::::::::::::.:::::::::::::::::::.:.: ::::::::
NP_001 QGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTT
1080 1090 1100 1110 1120 1130
1110 1120 1130 1140 1150 1160
pF1KE0 KSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRA
:.:::. ::: ::::::.::::::::::::::::::.::::.::::::::::::::::::
NP_001 KAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRA
1140 1150 1160 1170 1180 1190
1170 1180 1190 1200 1210 1220
pF1KE0 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
1200 1210 1220 1230 1240 1250
1230 1240 1250 1260 1270 1280
pF1KE0 LEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDEL
:::::..:::::::::::.::::::.:::::::::::.:::::.::::::::::::::::
NP_001 LEHEEQDEEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDEL
1260 1270 1280 1290 1300 1310
1290 1300 1310 1320 1330
pF1KE0 PSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLR---AIEDGNLEEM
::::::::::::::::::::::.::::::.:..:::::.:::::::. :::.:.:::.
NP_001 PSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKTLKAIEEGTLEEI
1320 1330 1340 1350 1360 1370
1340 1350 1360 1370 1380
pF1KE0 EEEVRLKKRKRRRNVDKD-----PA-------KEDVEKAKKRRGRPPAEKLSPNPPKLTK
::::: :: .:.:. :.: :. :.: : .:.::::::::::::::.:::
NP_001 EEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK
1380 1390 1400 1410 1420 1430
1390 1400 1410 1420 1430 1440
pF1KE0 QMNAIIDTVINYKDSS-GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYR
.:. :.:.::.::::: :::::::::::::::::::::::::::::::::::::::::::
NP_001 KMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYR
1440 1450 1460 1470 1480 1490
1450 1460 1470 1480 1490 1500
pF1KE0 SLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEE
::.::::::::::.:::::::::: :::::::::::: :.:::: ::..:: : .:::::
NP_001 SLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEE
1500 1510 1520 1530 1540 1550
1510 1520 1530 1540 1550 1560
pF1KE0 EDEEESESEAKSVKVKIKLNKKDDKGRDKGKG-KKRPNRG-KAKPVVSDFDSDEEQDERE
.:: ::::..::::::::..:. :..:. :: ..::.:: .::::::: ::.:::.: .
NP_001 GEEEGSESESRSVKVKIKLGRKE-KAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDR
1560 1570 1580 1590 1600
1570
pF1KE0 QSEGSGTDDE
.. :: :
NP_001 SGSGSEED
1610
1572 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 11:15:55 2016 done: Sun Nov 6 11:15:58 2016
Total Scan time: 21.580 Total Display time: 1.180
Function used was FASTA [36.3.4 Apr, 2011]