Result of FASTA (ccds) for
pFN21AE0797
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0797, 1572 aa
1>>>pF1KE0797 1572 - 1572 aa - 1572 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.5734+/-0.00132; mu= -19.6819+/- 0.080
mean_var=663.5545+/-135.112, 0's: 0 Z-trim(116.3): 127 B-trim: 0 in 0/54
Lambda= 0.049789
statistics sampled from 16747 (16862) to 16747 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.518), width: 16
Scan time: 7.370
The best scores are: opt bits E(32554)
CCDS34978.1 SMARCA2 gene_id:6595|Hs108|chr9 (1572) 10527 772.4 0
CCDS34977.1 SMARCA2 gene_id:6595|Hs108|chr9 (1590) 9415 692.5 2.8e-198
CCDS54218.1 SMARCA4 gene_id:6597|Hs108|chr19 (1613) 6400 475.9 4.5e-133
CCDS54217.1 SMARCA4 gene_id:6597|Hs108|chr19 (1614) 6364 473.3 2.7e-132
CCDS45973.1 SMARCA4 gene_id:6597|Hs108|chr19 (1616) 6320 470.2 2.4e-131
CCDS45972.1 SMARCA4 gene_id:6597|Hs108|chr19 (1617) 6313 469.7 3.4e-131
CCDS83338.1 SMARCA2 gene_id:6595|Hs108|chr9 (1514) 5900 440.0 2.8e-122
CCDS12253.1 SMARCA4 gene_id:6597|Hs108|chr19 (1647) 5584 417.3 2e-115
CCDS75807.1 SMARCA2 gene_id:6595|Hs108|chr9 ( 248) 1590 129.8 1.1e-29
CCDS83339.1 SMARCA2 gene_id:6595|Hs108|chr9 ( 276) 1585 129.5 1.5e-29
CCDS75808.1 SMARCA2 gene_id:6595|Hs108|chr9 ( 278) 1585 129.5 1.5e-29
CCDS47865.1 CHD7 gene_id:55636|Hs108|chr8 (2997) 1144 98.6 3.2e-19
CCDS32555.1 CHD3 gene_id:1107|Hs108|chr17 (1966) 1055 92.1 2e-17
CCDS32554.1 CHD3 gene_id:1107|Hs108|chr17 (2000) 1055 92.1 2e-17
CCDS32553.2 CHD3 gene_id:1107|Hs108|chr17 (2059) 1055 92.1 2e-17
CCDS57.1 CHD5 gene_id:26038|Hs108|chr1 (1954) 1040 91.0 4.1e-17
CCDS53885.1 CHD8 gene_id:57680|Hs108|chr14 (2581) 1037 90.8 5.9e-17
CCDS76510.1 CHD4 gene_id:1108|Hs108|chr12 (1905) 1032 90.4 6e-17
CCDS8552.1 CHD4 gene_id:1108|Hs108|chr12 (1912) 1032 90.4 6e-17
CCDS45081.1 CHD8 gene_id:57680|Hs108|chr14 (2302) 1032 90.5 7e-17
CCDS13317.1 CHD6 gene_id:84181|Hs108|chr20 (2715) 1026 90.1 1.1e-16
CCDS45485.1 CHD9 gene_id:80205|Hs108|chr16 (2881) 1014 89.2 2e-16
CCDS76865.1 CHD9 gene_id:80205|Hs108|chr16 (2897) 1014 89.2 2e-16
CCDS10071.1 INO80 gene_id:54617|Hs108|chr15 (1556) 902 81.0 3.3e-14
CCDS7229.1 ERCC6 gene_id:2074|Hs108|chr10 (1493) 882 79.5 8.7e-14
CCDS10689.2 SRCAP gene_id:10847|Hs108|chr16 (3230) 848 77.3 8.6e-13
>>CCDS34978.1 SMARCA2 gene_id:6595|Hs108|chr9 (1572 aa)
initn: 10527 init1: 10527 opt: 10527 Z-score: 4104.9 bits: 772.4 E(32554): 0
Smith-Waterman score: 10527; 100.0% identity (100.0% similar) in 1572 aa overlap (1-1572:1-1572)
10 20 30 40 50 60
pF1KE0 MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 GSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 QQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 QQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 AVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 AVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 LENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 LENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 QTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 QTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 ATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 TNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 TNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 ETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 LLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 LLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 NGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 NGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 PLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 PLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHIL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 AKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 AKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 TIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 TIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 KVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 KVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPY
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 MFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 IMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 IMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 VVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 VVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 AGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 AGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE0 RREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 RREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDAL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE0 TEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 TEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNP
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE0 PKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 PKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRN
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE0 HKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 HKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNE
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE0 EEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAKPVVSDFDSDEEQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 EEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAKPVVSDFDSDEEQDE
1510 1520 1530 1540 1550 1560
1570
pF1KE0 REQSEGSGTDDE
::::::::::::
CCDS34 REQSEGSGTDDE
1570
>>CCDS34977.1 SMARCA2 gene_id:6595|Hs108|chr9 (1590 aa)
initn: 9415 init1: 9415 opt: 9415 Z-score: 3673.2 bits: 692.5 E(32554): 2.8e-198
Smith-Waterman score: 10481; 98.9% identity (98.9% similar) in 1590 aa overlap (1-1572:1-1590)
10 20 30 40 50 60
pF1KE0 MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 GSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 QQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 QQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 AVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 AVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 LENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 LENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 QTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 QTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 ATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 TNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 TNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 ETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 LLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 LLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 NGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 NGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 PLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 PLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHIL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 AKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 AKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 TIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 TIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 KVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 KVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPY
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 MFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 IMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 IMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 VVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 VVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 AGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 AGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE0 RREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 RREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDAL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE0 TEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 TEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNP
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420
pF1KE0 PKLTKQMNAIIDTVINYKD------------------SSGRQLSEVFIQLPSRKELPEYY
::::::::::::::::::: :::::::::::::::::::::::
CCDS34 PKLTKQMNAIIDTVINYKDRCNVEKVPSNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYY
1390 1400 1410 1420 1430 1440
1430 1440 1450 1460 1470 1480
pF1KE0 ELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFK
1450 1460 1470 1480 1490 1500
1490 1500 1510 1520 1530 1540
pF1KE0 SARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 SARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNR
1510 1520 1530 1540 1550 1560
1550 1560 1570
pF1KE0 GKAKPVVSDFDSDEEQDEREQSEGSGTDDE
::::::::::::::::::::::::::::::
CCDS34 GKAKPVVSDFDSDEEQDEREQSEGSGTDDE
1570 1580 1590
>>CCDS54218.1 SMARCA4 gene_id:6597|Hs108|chr19 (1613 aa)
initn: 7066 init1: 4040 opt: 6400 Z-score: 2502.6 bits: 475.9 E(32554): 4.5e-133
Smith-Waterman score: 8141; 76.6% identity (89.0% similar) in 1624 aa overlap (1-1570:1-1613)
10 20 30 40 50
pF1KE0 MSTPTDP-GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPT
:::: : :. :.:::::::::::: .::::::: ::::.::::::::::::..::.::
CCDS54 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPIPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 MGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPP-HPGMGPPQSPMDQHSQ
.: .::..:::::::....:.::. .: . ..::: ::: : ::::: ::::::::
CCDS54 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 GYMSPHPSPLGAPEHVSSPMSGGGPTP-PQMPPSQPGALIPG-DPQAMSQPNRGPSPFSP
:: :::::. ::.:::. ..::. ::: . :: . : ::::..: ::::.::.
CCDS54 GY----PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQ
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 VQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQ----------
:::::::::.::::::::::::. ::.:::::: .::.:::. .
CCDS54 NQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGP
180 190 200 210 220 230
230 240 250 260 270
pF1KE0 -----------QQQQQQQQQQQQPQQQPPQPQT----QQQQQPALVNYNRPSGPGPELSG
. .. . . :.. :: :. . : :. : :: . ..
CCDS54 GPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAA
240 250 260 270 280 290
280 290 300 310 320
pF1KE0 P-STPQKLPVPAPGGRPSPAPPAAAQPPAAA-VPGPSVPQPA-PGQPSPVLQLQQKQSRI
: :::::: : : :::::::::. ::::. : :.. .:. :.::.:.. :.::::::
CCDS54 PTSTPQKLIPPQPTGRPSPAPPAV--PPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRI
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE0 SPIQKPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNF
.:::::.::::::::::::::::::::::::::::::::: :::::::.::::::::::
CCDS54 TPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNF
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE0 QRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKH
:::::::::.::::::.::::::.:::::::::.:::::.::::::::::::::::::::
CCDS54 QRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKH
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE0 QEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMA
:::::::::::::::::::::.::::::.:::::.:::::::::::.:::::::::::::
CCDS54 QEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMA
480 490 500 510 520 530
510 520 530 540 550 560
pF1KE0 EDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEE
:::::::::::::::.:::::::::::::::::.:: .:: ::.::::::....:: :
CCDS54 EDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AE
540 550 560 570 580 590
570 580 590 600 610 620
pF1KE0 NAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYE
:::: :.::::::.::.:::::::::: :.:.::.: : .::::.::.::::::::::
CCDS54 NAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYE
600 610 620 630 640 650
630 640 650 660 670 680
pF1KE0 VAPRSDSEESDSDYEEEDEEEESSRQET-------EEKILLDPNSEEVSEKDAKQIIETA
:::::::::: :. :::.::::. . :.: . ::.:..::: ::..:::.:
CCDS54 VAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENA
660 670 680 690 700 710
690 700 710 720 730 740
pF1KE0 KQDVDDEYSM-QYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYN
::::::::.. : ::: ::::.::::..:::.:::::..::.::.::..::::.:::::
CCDS54 KQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYN
720 730 740 750 760 770
750 760 770 780 790 800
pF1KE0 NNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVV
:::::::::::::::::::::::::::::::.:::.::::::::::::.:::::::::::
CCDS54 NNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVV
780 790 800 810 820 830
810 820 830 840 850 860
pF1KE0 KISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
:.::::.:: ::..::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
840 850 860 870 880 890
870 880 890 900 910 920
pF1KE0 CKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
CCDS54 CKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
900 910 920 930 940 950
930 940 950 960 970 980
pF1KE0 GERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRH
::.::::::::::::::::::::::::::::::::.::::::::::::::::::..::::
CCDS54 GEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH
960 970 980 990 1000 1010
990 1000 1010 1020 1030 1040
pF1KE0 MQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVI
:::::.:::::::::::::::.:::::::::::::::::::::::::::.::::...:..
CCDS54 MQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIV
1020 1030 1040 1050 1060 1070
1050 1060 1070 1080 1090 1100
pF1KE0 NGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTT
.: .:::::::::::::::::::::::.:::::::::::::::::::.:.: ::::::::
CCDS54 QGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTT
1080 1090 1100 1110 1120 1130
1110 1120 1130 1140 1150 1160
pF1KE0 KSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRA
:.:::. ::: ::::::.::::::::::::::::::.::::.::::::::::::::::::
CCDS54 KAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRA
1140 1150 1160 1170 1180 1190
1170 1180 1190 1200 1210 1220
pF1KE0 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
1200 1210 1220 1230 1240 1250
1230 1240 1250 1260 1270 1280
pF1KE0 LEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDEL
:::::..:::::::::::.::::::.:::::::::::.:::::.::::::::::::::::
CCDS54 LEHEEQDEEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDEL
1260 1270 1280 1290 1300 1310
1290 1300 1310 1320 1330 1340
pF1KE0 PSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEE
::::::::::::::::::::::.::::::.:..:::::.:::::::.:::.:.:::.:::
CCDS54 PSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEE
1320 1330 1340 1350 1360 1370
1350 1360 1370 1380
pF1KE0 VRLKKRKRRRNVDKD-----PA-------KEDVEKAKKRRGRPPAEKLSPNPPKLTKQMN
:: :: .:.:. :.: :. :.: : .:.::::::::::::::.:::.:.
CCDS54 VRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMK
1380 1390 1400 1410 1420 1430
1390 1400 1410 1420 1430 1440
pF1KE0 AIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGD
:.:.::.::::::::::::::::::::::::::::::::::::::::::::::::::.:
CCDS54 KIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLND
1440 1450 1460 1470 1480 1490
1450 1460 1470 1480 1490 1500
pF1KE0 LEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDEE
:::::::::.:::::::::: :::::::::::: :.:::: ::..:: : .::::: .::
CCDS54 LEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEE
1500 1510 1520 1530 1540 1550
1510 1520 1530 1540 1550 1560
pF1KE0 ESESEAKSVKVKIKLNKKDDKGRDKGKG-KKRPNRG-KAKPVVSDFDSDEEQDEREQSEG
::::..::::::::..:. :..:. :: ..::.:: .::::::: ::.:::.: ... :
CCDS54 GSESESRSVKVKIKLGRKE-KAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSG
1560 1570 1580 1590 1600
1570
pF1KE0 SGTDDE
: :
CCDS54 SEED
1610
>>CCDS54217.1 SMARCA4 gene_id:6597|Hs108|chr19 (1614 aa)
initn: 6900 init1: 4045 opt: 6364 Z-score: 2488.7 bits: 473.3 E(32554): 2.7e-132
Smith-Waterman score: 8129; 76.6% identity (88.9% similar) in 1625 aa overlap (1-1570:1-1614)
10 20 30 40 50
pF1KE0 MSTPTDP-GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPT
:::: : :. :.:::::::::::: .::::::: ::::.::::::::::::..::.::
CCDS54 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPIPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 MGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPP-HPGMGPPQSPMDQHSQ
.: .::..:::::::....:.::. .: . ..::: ::: : ::::: ::::::::
CCDS54 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 GYMSPHPSPLGAPEHVSSPMSGGGPTP-PQMPPSQPGALIPG-DPQAMSQPNRGPSPFSP
:: :::::. ::.:::. ..::. ::: . :: . : ::::..: ::::.::.
CCDS54 GY----PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQ
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 VQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQ----------
:::::::::.::::::::::::. ::.:::::: .::.:::. .
CCDS54 NQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGP
180 190 200 210 220 230
230 240 250 260 270
pF1KE0 -----------QQQQQQQQQQQQPQQQPPQPQT----QQQQQPALVNYNRPSGPGPELSG
. .. . . :.. :: :. . : :. : :: . ..
CCDS54 GPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAA
240 250 260 270 280 290
280 290 300 310 320
pF1KE0 P-STPQKLPVPAPGGRPSPAPPAAAQPPAAA-VPGPSVPQPA-PGQPSPVLQLQQKQSRI
: :::::: : : :::::::::. ::::. : :.. .:. :.::.:.. :.::::::
CCDS54 PTSTPQKLIPPQPTGRPSPAPPAV--PPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRI
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE0 SPIQKPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNF
.:::::.::::::::::::::::::::::::::::::::: :::::::.::::::::::
CCDS54 TPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNF
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE0 QRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKH
:::::::::.::::::.::::::.:::::::::.:::::.::::::::::::::::::::
CCDS54 QRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKH
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE0 QEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMA
:::::::::::::::::::::.::::::.:::::.:::::::::::.:::::::::::::
CCDS54 QEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMA
480 490 500 510 520 530
510 520 530 540 550 560
pF1KE0 EDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEE
:::::::::::::::.:::::::::::::::::.:: .:: ::.::::::....:: :
CCDS54 EDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AE
540 550 560 570 580 590
570 580 590 600 610 620
pF1KE0 NAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYE
:::: :.::::::.::.:::::::::: :.:.::.: : .::::.::.::::::::::
CCDS54 NAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYE
600 610 620 630 640 650
630 640 650 660 670 680
pF1KE0 VAPRSDSEESDSDYEEEDEEEESSRQET-------EEKILLDPNSEEVSEKDAKQIIETA
:::::::::: :. :::.::::. . :.: . ::.:..::: ::..:::.:
CCDS54 VAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENA
660 670 680 690 700 710
690 700 710 720 730 740
pF1KE0 KQDVDDEYSM-QYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYN
::::::::.. : ::: ::::.::::..:::.:::::..::.::.::..::::.:::::
CCDS54 KQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYN
720 730 740 750 760 770
750 760 770 780 790 800
pF1KE0 NNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVV
:::::::::::::::::::::::::::::::.:::.::::::::::::.:::::::::::
CCDS54 NNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVV
780 790 800 810 820 830
810 820 830 840 850 860
pF1KE0 KISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
:.::::.:: ::..::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
840 850 860 870 880 890
870 880 890 900 910 920
pF1KE0 CKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
CCDS54 CKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
900 910 920 930 940 950
930 940 950 960 970 980
pF1KE0 GERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRH
::.::::::::::::::::::::::::::::::::.::::::::::::::::::..::::
CCDS54 GEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH
960 970 980 990 1000 1010
990 1000 1010 1020 1030 1040
pF1KE0 MQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVI
:::::.:::::::::::::::.:::::::::::::::::::::::::::.::::...:..
CCDS54 MQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIV
1020 1030 1040 1050 1060 1070
1050 1060 1070 1080 1090 1100
pF1KE0 NGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTT
.: .:::::::::::::::::::::::.:::::::::::::::::::.:.: ::::::::
CCDS54 QGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTT
1080 1090 1100 1110 1120 1130
1110 1120 1130 1140 1150 1160
pF1KE0 KSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRA
:.:::. ::: ::::::.::::::::::::::::::.::::.::::::::::::::::::
CCDS54 KAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRA
1140 1150 1160 1170 1180 1190
1170 1180 1190 1200 1210 1220
pF1KE0 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
1200 1210 1220 1230 1240 1250
1230 1240 1250 1260 1270 1280
pF1KE0 LEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDEL
:::::..:::::::::::.::::::.:::::::::::.:::::.::::::::::::::::
CCDS54 LEHEEQDEEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDEL
1260 1270 1280 1290 1300 1310
1290 1300 1310 1320 1330 1340
pF1KE0 PSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEE
::::::::::::::::::::::.::::::.:..:::::.:::::::.:::.:.:::.:::
CCDS54 PSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEE
1320 1330 1340 1350 1360 1370
1350 1360 1370 1380
pF1KE0 VRLKKRKRRRNVDKD-----PA-------KEDVEKAKKRRGRPPAEKLSPNPPKLTKQMN
:: :: .:.:. :.: :. :.: : .:.::::::::::::::.:::.:.
CCDS54 VRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMK
1380 1390 1400 1410 1420 1430
1390 1400 1410 1420 1430 1440
pF1KE0 AIIDTVINYKDSS-GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLG
:.:.::.::::: :::::::::::::::::::::::::::::::::::::::::::::.
CCDS54 KIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLN
1440 1450 1460 1470 1480 1490
1450 1460 1470 1480 1490 1500
pF1KE0 DLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDE
::::::::::.:::::::::: :::::::::::: :.:::: ::..:: : .::::: .:
CCDS54 DLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEE
1500 1510 1520 1530 1540 1550
1510 1520 1530 1540 1550 1560
pF1KE0 EESESEAKSVKVKIKLNKKDDKGRDKGKG-KKRPNRG-KAKPVVSDFDSDEEQDEREQSE
: ::::..::::::::..:. :..:. :: ..::.:: .::::::: ::.:::.: ...
CCDS54 EGSESESRSVKVKIKLGRKE-KAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGS
1560 1570 1580 1590 1600
1570
pF1KE0 GSGTDDE
:: :
CCDS54 GSEED
1610
>>CCDS45973.1 SMARCA4 gene_id:6597|Hs108|chr19 (1616 aa)
initn: 6957 init1: 3931 opt: 6320 Z-score: 2471.6 bits: 470.2 E(32554): 2.4e-131
Smith-Waterman score: 8125; 76.5% identity (88.8% similar) in 1627 aa overlap (1-1570:1-1616)
10 20 30 40 50
pF1KE0 MSTPTDP-GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPT
:::: : :. :.:::::::::::: .::::::: ::::.::::::::::::..::.::
CCDS45 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPIPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 MGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPP-HPGMGPPQSPMDQHSQ
.: .::..:::::::....:.::. .: . ..::: ::: : ::::: ::::::::
CCDS45 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 GYMSPHPSPLGAPEHVSSPMSGGGPTP-PQMPPSQPGALIPG-DPQAMSQPNRGPSPFSP
:: :::::. ::.:::. ..::. ::: . :: . : ::::..: ::::.::.
CCDS45 GY----PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQ
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 VQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQ----------
:::::::::.::::::::::::. ::.:::::: .::.:::. .
CCDS45 NQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGP
180 190 200 210 220 230
230 240 250 260 270
pF1KE0 -----------QQQQQQQQQQQQPQQQPPQPQT----QQQQQPALVNYNRPSGPGPELSG
. .. . . :.. :: :. . : :. : :: . ..
CCDS45 GPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAA
240 250 260 270 280 290
280 290 300 310 320
pF1KE0 P-STPQKLPVPAPGGRPSPAPPAAAQPPAAA-VPGPSVPQPA-PGQPSPVLQLQQKQSRI
: :::::: : : :::::::::. ::::. : :.. .:. :.::.:.. :.::::::
CCDS45 PTSTPQKLIPPQPTGRPSPAPPAV--PPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRI
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE0 SPIQKPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNF
.:::::.::::::::::::::::::::::::::::::::: :::::::.::::::::::
CCDS45 TPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNF
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE0 QRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKH
:::::::::.::::::.::::::.:::::::::.:::::.::::::::::::::::::::
CCDS45 QRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKH
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE0 QEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMA
:::::::::::::::::::::.::::::.:::::.:::::::::::.:::::::::::::
CCDS45 QEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMA
480 490 500 510 520 530
510 520 530 540 550 560
pF1KE0 EDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEE
:::::::::::::::.:::::::::::::::::.:: .:: ::.::::::....:: :
CCDS45 EDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AE
540 550 560 570 580 590
570 580 590 600 610 620
pF1KE0 NAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYE
:::: :.::::::.::.:::::::::: :.:.::.: : .::::.::.::::::::::
CCDS45 NAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYE
600 610 620 630 640 650
630 640 650 660 670 680
pF1KE0 VAPRSDSEESDSDYEEEDEEEESSRQET-------EEKILLDPNSEEVSEKDAKQIIETA
:::::::::: :. :::.::::. . :.: . ::.:..::: ::..:::.:
CCDS45 VAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENA
660 670 680 690 700 710
690 700 710 720 730 740
pF1KE0 KQDVDDEYSM-QYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYN
::::::::.. : ::: ::::.::::..:::.:::::..::.::.::..::::.:::::
CCDS45 KQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYN
720 730 740 750 760 770
750 760 770 780 790 800
pF1KE0 NNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVV
:::::::::::::::::::::::::::::::.:::.::::::::::::.:::::::::::
CCDS45 NNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVV
780 790 800 810 820 830
810 820 830 840 850 860
pF1KE0 KISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
:.::::.:: ::..::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
840 850 860 870 880 890
870 880 890 900 910 920
pF1KE0 CKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
CCDS45 CKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
900 910 920 930 940 950
930 940 950 960 970 980
pF1KE0 GERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRH
::.::::::::::::::::::::::::::::::::.::::::::::::::::::..::::
CCDS45 GEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH
960 970 980 990 1000 1010
990 1000 1010 1020 1030 1040
pF1KE0 MQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVI
:::::.:::::::::::::::.:::::::::::::::::::::::::::.::::...:..
CCDS45 MQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIV
1020 1030 1040 1050 1060 1070
1050 1060 1070 1080 1090 1100
pF1KE0 NGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTT
.: .:::::::::::::::::::::::.:::::::::::::::::::.:.: ::::::::
CCDS45 QGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTT
1080 1090 1100 1110 1120 1130
1110 1120 1130 1140 1150 1160
pF1KE0 KSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRA
:.:::. ::: ::::::.::::::::::::::::::.::::.::::::::::::::::::
CCDS45 KAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRA
1140 1150 1160 1170 1180 1190
1170 1180 1190 1200 1210 1220
pF1KE0 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
1200 1210 1220 1230 1240 1250
1230 1240 1250 1260 1270 1280
pF1KE0 LEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDEL
:::::..:::::::::::.::::::.:::::::::::.:::::.::::::::::::::::
CCDS45 LEHEEQDEEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDEL
1260 1270 1280 1290 1300 1310
1290 1300 1310 1320 1330
pF1KE0 PSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLR---AIEDGNLEEM
::::::::::::::::::::::.::::::.:..:::::.:::::::. :::.:.:::.
CCDS45 PSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKTLKAIEEGTLEEI
1320 1330 1340 1350 1360 1370
1340 1350 1360 1370 1380
pF1KE0 EEEVRLKKRKRRRNVDKD-----PA-------KEDVEKAKKRRGRPPAEKLSPNPPKLTK
::::: :: .:.:. :.: :. :.: : .:.::::::::::::::.:::
CCDS45 EEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK
1380 1390 1400 1410 1420 1430
1390 1400 1410 1420 1430 1440
pF1KE0 QMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRS
.:. :.:.::.:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KMKKIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRS
1440 1450 1460 1470 1480 1490
1450 1460 1470 1480 1490 1500
pF1KE0 LGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEE
:.::::::::::.:::::::::: :::::::::::: :.:::: ::..:: : .:::::
CCDS45 LNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEG
1500 1510 1520 1530 1540 1550
1510 1520 1530 1540 1550 1560
pF1KE0 DEEESESEAKSVKVKIKLNKKDDKGRDKGKG-KKRPNRG-KAKPVVSDFDSDEEQDEREQ
.:: ::::..::::::::..:. :..:. :: ..::.:: .::::::: ::.:::.: ..
CCDS45 EEEGSESESRSVKVKIKLGRKE-KAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRS
1560 1570 1580 1590 1600
1570
pF1KE0 SEGSGTDDE
. :: :
CCDS45 GSGSEED
1610
>>CCDS45972.1 SMARCA4 gene_id:6597|Hs108|chr19 (1617 aa)
initn: 6989 init1: 3931 opt: 6313 Z-score: 2468.8 bits: 469.7 E(32554): 3.4e-131
Smith-Waterman score: 8113; 76.4% identity (88.8% similar) in 1628 aa overlap (1-1570:1-1617)
10 20 30 40 50
pF1KE0 MSTPTDP-GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPT
:::: : :. :.:::::::::::: .::::::: ::::.::::::::::::..::.::
CCDS45 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPIPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 MGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPP-HPGMGPPQSPMDQHSQ
.: .::..:::::::....:.::. .: . ..::: ::: : ::::: ::::::::
CCDS45 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 GYMSPHPSPLGAPEHVSSPMSGGGPTP-PQMPPSQPGALIPG-DPQAMSQPNRGPSPFSP
:: :::::. ::.:::. ..::. ::: . :: . : ::::..: ::::.::.
CCDS45 GY----PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQ
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 VQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQ----------
:::::::::.::::::::::::. ::.:::::: .::.:::. .
CCDS45 NQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGP
180 190 200 210 220 230
230 240 250 260 270
pF1KE0 -----------QQQQQQQQQQQQPQQQPPQPQT----QQQQQPALVNYNRPSGPGPELSG
. .. . . :.. :: :. . : :. : :: . ..
CCDS45 GPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAA
240 250 260 270 280 290
280 290 300 310 320
pF1KE0 P-STPQKLPVPAPGGRPSPAPPAAAQPPAAA-VPGPSVPQPA-PGQPSPVLQLQQKQSRI
: :::::: : : :::::::::. ::::. : :.. .:. :.::.:.. :.::::::
CCDS45 PTSTPQKLIPPQPTGRPSPAPPAV--PPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRI
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE0 SPIQKPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNF
.:::::.::::::::::::::::::::::::::::::::: :::::::.::::::::::
CCDS45 TPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNF
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE0 QRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKH
:::::::::.::::::.::::::.:::::::::.:::::.::::::::::::::::::::
CCDS45 QRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKH
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE0 QEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMA
:::::::::::::::::::::.::::::.:::::.:::::::::::.:::::::::::::
CCDS45 QEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMA
480 490 500 510 520 530
510 520 530 540 550 560
pF1KE0 EDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEE
:::::::::::::::.:::::::::::::::::.:: .:: ::.::::::....:: :
CCDS45 EDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AE
540 550 560 570 580 590
570 580 590 600 610 620
pF1KE0 NAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYE
:::: :.::::::.::.:::::::::: :.:.::.: : .::::.::.::::::::::
CCDS45 NAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYE
600 610 620 630 640 650
630 640 650 660 670 680
pF1KE0 VAPRSDSEESDSDYEEEDEEEESSRQET-------EEKILLDPNSEEVSEKDAKQIIETA
:::::::::: :. :::.::::. . :.: . ::.:..::: ::..:::.:
CCDS45 VAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENA
660 670 680 690 700 710
690 700 710 720 730 740
pF1KE0 KQDVDDEYSM-QYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYN
::::::::.. : ::: ::::.::::..:::.:::::..::.::.::..::::.:::::
CCDS45 KQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYN
720 730 740 750 760 770
750 760 770 780 790 800
pF1KE0 NNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVV
:::::::::::::::::::::::::::::::.:::.::::::::::::.:::::::::::
CCDS45 NNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVV
780 790 800 810 820 830
810 820 830 840 850 860
pF1KE0 KISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
:.::::.:: ::..::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
840 850 860 870 880 890
870 880 890 900 910 920
pF1KE0 CKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
CCDS45 CKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
900 910 920 930 940 950
930 940 950 960 970 980
pF1KE0 GERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRH
::.::::::::::::::::::::::::::::::::.::::::::::::::::::..::::
CCDS45 GEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH
960 970 980 990 1000 1010
990 1000 1010 1020 1030 1040
pF1KE0 MQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVI
:::::.:::::::::::::::.:::::::::::::::::::::::::::.::::...:..
CCDS45 MQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIV
1020 1030 1040 1050 1060 1070
1050 1060 1070 1080 1090 1100
pF1KE0 NGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTT
.: .:::::::::::::::::::::::.:::::::::::::::::::.:.: ::::::::
CCDS45 QGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTT
1080 1090 1100 1110 1120 1130
1110 1120 1130 1140 1150 1160
pF1KE0 KSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRA
:.:::. ::: ::::::.::::::::::::::::::.::::.::::::::::::::::::
CCDS45 KAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRA
1140 1150 1160 1170 1180 1190
1170 1180 1190 1200 1210 1220
pF1KE0 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
1200 1210 1220 1230 1240 1250
1230 1240 1250 1260 1270 1280
pF1KE0 LEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDEL
:::::..:::::::::::.::::::.:::::::::::.:::::.::::::::::::::::
CCDS45 LEHEEQDEEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDEL
1260 1270 1280 1290 1300 1310
1290 1300 1310 1320 1330
pF1KE0 PSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLR---AIEDGNLEEM
::::::::::::::::::::::.::::::.:..:::::.:::::::. :::.:.:::.
CCDS45 PSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKTLKAIEEGTLEEI
1320 1330 1340 1350 1360 1370
1340 1350 1360 1370 1380
pF1KE0 EEEVRLKKRKRRRNVDKD-----PA-------KEDVEKAKKRRGRPPAEKLSPNPPKLTK
::::: :: .:.:. :.: :. :.: : .:.::::::::::::::.:::
CCDS45 EEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK
1380 1390 1400 1410 1420 1430
1390 1400 1410 1420 1430 1440
pF1KE0 QMNAIIDTVINYKDSS-GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYR
.:. :.:.::.::::: :::::::::::::::::::::::::::::::::::::::::::
CCDS45 KMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYR
1440 1450 1460 1470 1480 1490
1450 1460 1470 1480 1490 1500
pF1KE0 SLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEE
::.::::::::::.:::::::::: :::::::::::: :.:::: ::..:: : .:::::
CCDS45 SLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEE
1500 1510 1520 1530 1540 1550
1510 1520 1530 1540 1550 1560
pF1KE0 EDEEESESEAKSVKVKIKLNKKDDKGRDKGKG-KKRPNRG-KAKPVVSDFDSDEEQDERE
.:: ::::..::::::::..:. :..:. :: ..::.:: .::::::: ::.:::.: .
CCDS45 GEEEGSESESRSVKVKIKLGRKE-KAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDR
1560 1570 1580 1590 1600
1570
pF1KE0 QSEGSGTDDE
.. :: :
CCDS45 SGSGSEED
1610
>>CCDS83338.1 SMARCA2 gene_id:6595|Hs108|chr9 (1514 aa)
initn: 5900 init1: 5900 opt: 5900 Z-score: 2308.9 bits: 440.0 E(32554): 2.8e-122
Smith-Waterman score: 10004; 96.3% identity (96.3% similar) in 1572 aa overlap (1-1572:1-1514)
10 20 30 40 50 60
pF1KE0 MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 GSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 MSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 QQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 QQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 AVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 AVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 LENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 LENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 QTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 QTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 ATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 ATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 TNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 TNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 ETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 ETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 LLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 LLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 NGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 NGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 PLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 PLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHIL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 AKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLP
::::::::::::::::::::::::::
CCDS83 AKIRWKYMIVDEGHRMKNHHCKLTQV----------------------------------
850 860
910 920 930 940 950 960
pF1KE0 TIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPE
::::::::::::::::::::::::::::::::::::
CCDS83 ------------------------DLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPE
870 880 890 900
970 980 990 1000 1010 1020
pF1KE0 KVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 KVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPY
910 920 930 940 950 960
1030 1040 1050 1060 1070 1080
pF1KE0 MFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 MFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMT
970 980 990 1000 1010 1020
1090 1100 1110 1120 1130 1140
pF1KE0 IMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 IMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADT
1030 1040 1050 1060 1070 1080
1150 1160 1170 1180 1190 1200
pF1KE0 VVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 VVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQ
1090 1100 1110 1120 1130 1140
1210 1220 1230 1240 1250 1260
pF1KE0 AGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 AGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDR
1150 1160 1170 1180 1190 1200
1270 1280 1290 1300 1310 1320
pF1KE0 RREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 RREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDAL
1210 1220 1230 1240 1250 1260
1330 1340 1350 1360 1370 1380
pF1KE0 TEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 TEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNP
1270 1280 1290 1300 1310 1320
1390 1400 1410 1420 1430 1440
pF1KE0 PKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 PKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRN
1330 1340 1350 1360 1370 1380
1450 1460 1470 1480 1490 1500
pF1KE0 HKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 HKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNE
1390 1400 1410 1420 1430 1440
1510 1520 1530 1540 1550 1560
pF1KE0 EEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAKPVVSDFDSDEEQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 EEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAKPVVSDFDSDEEQDE
1450 1460 1470 1480 1490 1500
1570
pF1KE0 REQSEGSGTDDE
::::::::::::
CCDS83 REQSEGSGTDDE
1510
>>CCDS12253.1 SMARCA4 gene_id:6597|Hs108|chr19 (1647 aa)
initn: 6217 init1: 3300 opt: 5584 Z-score: 2185.7 bits: 417.3 E(32554): 2e-115
Smith-Waterman score: 8024; 75.3% identity (87.3% similar) in 1645 aa overlap (1-1557:1-1634)
10 20 30 40 50
pF1KE0 MSTPTDP-GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPT
:::: : :. :.:::::::::::: .::::::: ::::.::::::::::::..::.::
CCDS12 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPIPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 MGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPP-HPGMGPPQSPMDQHSQ
.: .::..:::::::....:.::. .: . ..::: ::: : ::::: ::::::::
CCDS12 QGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 GYMSPHPSPLGAPEHVSSPMSGGGPTP-PQMPPSQPGALIPG-DPQAMSQPNRGPSPFSP
:: :::::. ::.:::. ..::. ::: . :: . : ::::..: ::::.::.
CCDS12 GY----PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQ
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 VQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQ----------
:::::::::.::::::::::::. ::.:::::: .::.:::. .
CCDS12 NQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGP
180 190 200 210 220 230
230 240 250 260 270
pF1KE0 -----------QQQQQQQQQQQQPQQQPPQPQT----QQQQQPALVNYNRPSGPGPELSG
. .. . . :.. :: :. . : :. : :: . ..
CCDS12 GPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAA
240 250 260 270 280 290
280 290 300 310 320
pF1KE0 P-STPQKLPVPAPGGRPSPAPPAAAQPPAAA-VPGPSVPQPA-PGQPSPVLQLQQKQSRI
: :::::: : : :::::::::. ::::. : :.. .:. :.::.:.. :.::::::
CCDS12 PTSTPQKLIPPQPTGRPSPAPPAV--PPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRI
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE0 SPIQKPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNF
.:::::.::::::::::::::::::::::::::::::::: :::::::.::::::::::
CCDS12 TPIQKPRGLDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNF
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE0 QRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKH
:::::::::.::::::.::::::.:::::::::.:::::.::::::::::::::::::::
CCDS12 QRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKH
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE0 QEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMA
:::::::::::::::::::::.::::::.:::::.:::::::::::.:::::::::::::
CCDS12 QEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMA
480 490 500 510 520 530
510 520 530 540 550 560
pF1KE0 EDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEE
:::::::::::::::.:::::::::::::::::.:: .:: ::.::::::....:: :
CCDS12 EDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKA--E
540 550 560 570 580 590
570 580 590 600 610 620
pF1KE0 NAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYE
:::: :.::::::.::.:::::::::: :.:.::.: : .::::.::.::::::::::
CCDS12 NAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYE
600 610 620 630 640 650
630 640 650 660 670 680
pF1KE0 VAPRSDSEESDSDYEEEDEEEESSRQET-------EEKILLDPNSEEVSEKDAKQIIETA
:::::::::: :. :::.::::. . :.: . ::.:..::: ::..:::.:
CCDS12 VAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENA
660 670 680 690 700 710
690 700 710 720 730 740
pF1KE0 KQDVDDEYSM-QYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYN
::::::::.. : ::: ::::.::::..:::.:::::..::.::.::..::::.:::::
CCDS12 KQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYN
720 730 740 750 760 770
750 760 770 780 790 800
pF1KE0 NNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVV
:::::::::::::::::::::::::::::::.:::.::::::::::::.:::::::::::
CCDS12 NNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVV
780 790 800 810 820 830
810 820 830 840 850 860
pF1KE0 KISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
:.::::.:: ::..::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 KVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
840 850 860 870 880 890
870 880 890 900 910 920
pF1KE0 CKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
CCDS12 CKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMT
900 910 920 930 940 950
930 940 950 960 970 980
pF1KE0 GERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRH
::.::::::::::::::::::::::::::::::::.::::::::::::::::::..::::
CCDS12 GEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH
960 970 980 990 1000 1010
990 1000 1010 1020 1030 1040
pF1KE0 MQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVI
:::::.:::::::::::::::.:::::::::::::::::::::::::::.::::...:..
CCDS12 MQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIV
1020 1030 1040 1050 1060 1070
1050 1060 1070 1080 1090 1100
pF1KE0 NGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTT
.: .:::::::::::::::::::::::.:::::::::::::::::::.:.: ::::::::
CCDS12 QGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTT
1080 1090 1100 1110 1120 1130
1110 1120 1130 1140 1150 1160
pF1KE0 KSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRA
:.:::. ::: ::::::.::::::::::::::::::.::::.::::::::::::::::::
CCDS12 KAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRA
1140 1150 1160 1170 1180 1190
1170 1180 1190 1200 1210 1220
pF1KE0 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAI
1200 1210 1220 1230 1240 1250
1230 1240
pF1KE0 LEHEEENE---------------------------------EEDEVPDDETLNQMIARRE
:::::..: ::::::::::.::::::.:
CCDS12 LEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHE
1260 1270 1280 1290 1300 1310
1250 1260 1270 1280 1290 1300
pF1KE0 EEFDLFMRMDMDRRREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRG
::::::::::.:::::.::::::::::::::::::::::::::::::::::::::.::::
CCDS12 EEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRG
1320 1330 1340 1350 1360 1370
1310 1320 1330 1340 1350
pF1KE0 SRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKD-----PA-----
::.:..:::::.:::::::.:::.:.:::.::::: :: .:.:. :.: :.
CCDS12 SRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRS
1380 1390 1400 1410 1420 1430
1360 1370 1380 1390 1400 1410
pF1KE0 --KEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDSS-GRQLSEVFIQLPS
:.: : .:.::::::::::::::.:::.:. :.:.::.::::: :::::::::::::
CCDS12 RDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPS
1440 1450 1460 1470 1480 1490
1420 1430 1440 1450 1460 1470
pF1KE0 RKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDS
::::::::::::::::::::::::::::::::.::::::::::.:::::::::: :::::
CCDS12 RKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDS
1500 1510 1520 1530 1540 1550
1480 1490 1500 1510 1520 1530
pF1KE0 IVLQSVFKSARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKG
::::::: :.:::: ::..:: : .::::: .:: ::::..::::::::..:. :..:.
CCDS12 IVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKE-KAQDRL
1560 1570 1580 1590 1600
1540 1550 1560 1570
pF1KE0 KG-KKRPNRG-KAKPVVSDFDSDEEQDEREQSEGSGTDDE
:: ..::.:: .::::::: ::.::
CCDS12 KGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED
1610 1620 1630 1640
>>CCDS75807.1 SMARCA2 gene_id:6595|Hs108|chr9 (248 aa)
initn: 1582 init1: 1582 opt: 1590 Z-score: 646.7 bits: 129.8 E(32554): 1.1e-29
Smith-Waterman score: 1590; 99.6% identity (99.6% similar) in 248 aa overlap (1325-1572:2-248)
1300 1310 1320 1330 1340 1350
pF1KE0 TCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDK
:: :::::::::::::::::::::::::::
CCDS75 MWL-AIEDGNLEEMEEEVRLKKRKRRRNVDK
10 20 30
1360 1370 1380 1390 1400 1410
pF1KE0 DPAKEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 DPAKEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPS
40 50 60 70 80 90
1420 1430 1440 1450 1460 1470
pF1KE0 RKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 RKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDS
100 110 120 130 140 150
1480 1490 1500 1510 1520 1530
pF1KE0 IVLQSVFKSARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 IVLQSVFKSARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKG
160 170 180 190 200 210
1540 1550 1560 1570
pF1KE0 KGKKRPNRGKAKPVVSDFDSDEEQDEREQSEGSGTDDE
::::::::::::::::::::::::::::::::::::::
CCDS75 KGKKRPNRGKAKPVVSDFDSDEEQDEREQSEGSGTDDE
220 230 240
>>CCDS83339.1 SMARCA2 gene_id:6595|Hs108|chr9 (276 aa)
initn: 1585 init1: 1585 opt: 1585 Z-score: 644.1 bits: 129.5 E(32554): 1.5e-29
Smith-Waterman score: 1585; 99.6% identity (100.0% similar) in 246 aa overlap (1327-1572:31-276)
1300 1310 1320 1330 1340 1350
pF1KE0 EEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDP
.:::::::::::::::::::::::::::::
CCDS83 MKRLAARCFAGLLILSPLTVISDSRPADSGKAIEDGNLEEMEEEVRLKKRKRRRNVDKDP
10 20 30 40 50 60
1360 1370 1380 1390 1400 1410
pF1KE0 AKEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPSRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 AKEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPSRK
70 80 90 100 110 120
1420 1430 1440 1450 1460 1470
pF1KE0 ELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 ELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIV
130 140 150 160 170 180
1480 1490 1500 1510 1520 1530
pF1KE0 LQSVFKSARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 LQSVFKSARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKG
190 200 210 220 230 240
1540 1550 1560 1570
pF1KE0 KKRPNRGKAKPVVSDFDSDEEQDEREQSEGSGTDDE
::::::::::::::::::::::::::::::::::::
CCDS83 KKRPNRGKAKPVVSDFDSDEEQDEREQSEGSGTDDE
250 260 270
1572 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 11:15:53 2016 done: Sun Nov 6 11:15:55 2016
Total Scan time: 7.370 Total Display time: 0.950
Function used was FASTA [36.3.4 Apr, 2011]