Result of FASTA (omim) for
pFN21AE0766
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0766, 438 aa
1>>>pF1KE0766 438 - 438 aa - 438 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4667+/-0.000549; mu= 10.5905+/- 0.035
mean_var=292.0956+/-62.718, 0's: 0 Z-trim(115.9): 192 B-trim: 1376 in 1/55
Lambda= 0.075043
statistics sampled from 26502 (26707) to 26502 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.313), width: 16
Scan time: 7.540
The best scores are: opt bits E(85289)
NP_065097 (OMIM: 400027,415000) deleted in azoospe ( 438) 3084 347.9 3.1e-95
NP_001005785 (OMIM: 400026,415000) deleted in azoo ( 534) 2751 312.0 2.5e-84
NP_065096 (OMIM: 400026,415000) deleted in azoospe ( 558) 2748 311.7 3.2e-84
XP_011529785 (OMIM: 400003,415000) PREDICTED: dele ( 529) 2600 295.6 2e-79
XP_011529784 (OMIM: 400003,415000) PREDICTED: dele ( 694) 2600 295.8 2.4e-79
NP_004072 (OMIM: 400003,415000) deleted in azoospe ( 744) 2600 295.8 2.5e-79
NP_001005786 (OMIM: 400026,415000) deleted in azoo ( 366) 2250 257.5 4.2e-68
NP_001342 (OMIM: 601486) deleted in azoospermia-li ( 295) 1077 130.3 6.4e-30
NP_001177740 (OMIM: 601486) deleted in azoospermia ( 315) 1070 129.6 1.1e-29
NP_149019 (OMIM: 606165) protein boule-like isofor ( 283) 336 50.1 8.8e-06
NP_001271291 (OMIM: 606165) protein boule-like iso ( 289) 336 50.1 8.9e-06
NP_932074 (OMIM: 606165) protein boule-like isofor ( 295) 336 50.1 9e-06
XP_006712778 (OMIM: 606165) PREDICTED: protein bou ( 291) 332 49.7 1.2e-05
XP_016860262 (OMIM: 606165) PREDICTED: protein bou ( 220) 323 48.5 2e-05
XP_011509996 (OMIM: 606165) PREDICTED: protein bou ( 305) 323 48.7 2.4e-05
XP_011509995 (OMIM: 606165) PREDICTED: protein bou ( 313) 323 48.8 2.5e-05
XP_011509994 (OMIM: 606165) PREDICTED: protein bou ( 317) 323 48.8 2.5e-05
NP_001271290 (OMIM: 606165) protein boule-like iso ( 339) 323 48.8 2.6e-05
>>NP_065097 (OMIM: 400027,415000) deleted in azoospermia (438 aa)
initn: 3084 init1: 3084 opt: 3084 Z-score: 1830.8 bits: 347.9 E(85289): 3.1e-95
Smith-Waterman score: 3084; 100.0% identity (100.0% similar) in 438 aa overlap (1-438:1-438)
10 20 30 40 50 60
pF1KE0 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 GYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PAYPNSPVQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PAYPNSPVQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNL
370 380 390 400 410 420
430
pF1KE0 WTEAYKWWYLVCLIQRRD
::::::::::::::::::
NP_065 WTEAYKWWYLVCLIQRRD
430
>>NP_001005785 (OMIM: 400026,415000) deleted in azoosper (534 aa)
initn: 2740 init1: 2740 opt: 2751 Z-score: 1635.1 bits: 312.0 E(85289): 2.5e-84
Smith-Waterman score: 2751; 95.6% identity (97.6% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KE0 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVAT
:::::::::::::::::::::: :::::.:: :::.::::::::::::::::::::::::
NP_001 PAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 GYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAF
::::::::::::::::::::::::::::::::::::::::.:::::.::::.::::::::
NP_001 GYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PAYPNSPVQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNL
::::.:: ::::::::::::::::::::.: :::::::. ::::: : :
NP_001 PAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTT
370 380 390 400 410 420
430
pF1KE0 WTEAYKWWYLVCLIQRRD
NP_001 GYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAF
430 440 450 460 470 480
>--
initn: 842 init1: 842 opt: 842 Z-score: 518.1 bits: 105.3 E(85289): 4.1e-22
Smith-Waterman score: 842; 94.3% identity (98.4% similar) in 122 aa overlap (317-438:413-534)
290 300 310 320 330 340
pF1KE0 AFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQV
.:: ::::::::::::::::::::.:::::
NP_001 AFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQV
390 400 410 420 430 440
350 360 370 380 390 400
pF1KE0 ATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQ
.::::.::::::::::::.:: ::::::::::::::::::::::::::::::::::::::
NP_001 TTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQ
450 460 470 480 490 500
410 420 430
pF1KE0 MPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
::::::::::::::::::::::::::::::::
NP_001 MPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
510 520 530
>>NP_065096 (OMIM: 400026,415000) deleted in azoospermia (558 aa)
initn: 2737 init1: 2737 opt: 2748 Z-score: 1633.1 bits: 311.7 E(85289): 3.2e-84
Smith-Waterman score: 2748; 95.6% identity (97.3% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KE0 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVAT
:::::::::::::::::::::: :::::.:: :::.::::::::::::::::::::::::
NP_065 PAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 GYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAF
::::::::::::::::::::::::::::::::::::::::::: ::.::::.::::::::
NP_065 GYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PAYPNSPVQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNL
::::.:: ::::::::::::::::::::.: :::::::. ::::: : :
NP_065 PAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTT
370 380 390 400 410 420
430
pF1KE0 WTEAYKWWYLVCLIQRRD
NP_065 GYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAF
430 440 450 460 470 480
>--
initn: 998 init1: 998 opt: 998 Z-score: 609.2 bits: 122.2 E(85289): 3.4e-27
Smith-Waterman score: 998; 93.2% identity (98.6% similar) in 146 aa overlap (293-438:413-558)
270 280 290 300 310 320
pF1KE0 AFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQV
.:::::.::::.::::::::::::.:: ::
NP_065 AFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQV
390 400 410 420 430 440
330 340 350 360 370 380
pF1KE0 TTGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQ
::::::::::::::::::.:::::.::::.::::::::::::.:: ::::::::::::::
NP_065 TTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQ
450 460 470 480 490 500
390 400 410 420 430
pF1KE0 AFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
510 520 530 540 550
>>XP_011529785 (OMIM: 400003,415000) PREDICTED: deleted (529 aa)
initn: 2589 init1: 2589 opt: 2600 Z-score: 1546.7 bits: 295.6 E(85289): 2e-79
Smith-Waterman score: 2819; 93.4% identity (94.1% similar) in 437 aa overlap (2-438:117-529)
10 20 30
pF1KE0 MSAANPETPNSTISREASTQSSSAAASQGWV
::::::::::::::::::::::::::::::
XP_011 PQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWV
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE0 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE0 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE0 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE0 NYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSP
::::::::::::::::::::::::::::::::::::::::::::::::::: :::::.::
XP_011 NYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSP
330 340 350 360 370 380
280 290 300 310 320 330
pF1KE0 VQVTTGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVY
:::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVY
390 400 410 420 430 440
340 350 360 370 380 390
pF1KE0 NYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSA
:::::::::.::::: :::::::::::::::::::::
XP_011 NYQAFPAYPSSPFQV------------------------TTGYQLPVYNYQAFPAYPNSA
450 460 470 480
400 410 420 430
pF1KE0 VQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
490 500 510 520
>--
initn: 807 init1: 807 opt: 807 Z-score: 497.6 bits: 101.5 E(85289): 5.6e-21
Smith-Waterman score: 807; 100.0% identity (100.0% similar) in 116 aa overlap (51-166:1-116)
30 40 50 60 70 80
pF1KE0 SSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSK
::::::::::::::::::::::::::::::
XP_011 MDETEIGSCFGRYGSVKEVKIITNRTGVSK
10 20 30
90 100 110 120 130 140
pF1KE0 GYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQ
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE0 NVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAF
::::::::::::::::::::::::::
XP_011 NVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWVLPEG
100 110 120 130 140 150
>>XP_011529784 (OMIM: 400003,415000) PREDICTED: deleted (694 aa)
initn: 2653 init1: 2589 opt: 2600 Z-score: 1545.6 bits: 295.8 E(85289): 2.4e-79
Smith-Waterman score: 2819; 93.4% identity (94.1% similar) in 437 aa overlap (2-438:282-694)
10 20 30
pF1KE0 MSAANPETPNSTISREASTQSSSAAASQGWV
::::::::::::::::::::::::::::::
XP_011 PQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWV
260 270 280 290 300 310
40 50 60 70 80 90
pF1KE0 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
320 330 340 350 360 370
100 110 120 130 140 150
pF1KE0 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
380 390 400 410 420 430
160 170 180 190 200 210
pF1KE0 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
440 450 460 470 480 490
220 230 240 250 260 270
pF1KE0 NYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSP
::::::::::::::::::::::::::::::::::::::::::::::::::: :::::.::
XP_011 NYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSP
500 510 520 530 540 550
280 290 300 310 320 330
pF1KE0 VQVTTGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVY
:::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVY
560 570 580 590 600 610
340 350 360 370 380 390
pF1KE0 NYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSA
:::::::::.::::: :::::::::::::::::::::
XP_011 NYQAFPAYPSSPFQV------------------------TTGYQLPVYNYQAFPAYPNSA
620 630 640
400 410 420 430
pF1KE0 VQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
650 660 670 680 690
>--
initn: 1118 init1: 1118 opt: 1118 Z-score: 678.4 bits: 135.3 E(85289): 4.7e-31
Smith-Waterman score: 1118; 100.0% identity (100.0% similar) in 165 aa overlap (2-166:117-281)
10 20 30
pF1KE0 MSAANPETPNSTISREASTQSSSAAASQGWV
::::::::::::::::::::::::::::::
XP_011 PQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWV
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE0 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE0 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE0 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
:::::::::::::::
XP_011 LQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGG
270 280 290 300 310 320
>--
initn: 807 init1: 807 opt: 807 Z-score: 496.5 bits: 101.7 E(85289): 6.5e-21
Smith-Waterman score: 807; 100.0% identity (100.0% similar) in 116 aa overlap (51-166:1-116)
30 40 50 60 70 80
pF1KE0 SSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSK
::::::::::::::::::::::::::::::
XP_011 MDETEIGSCFGRYGSVKEVKIITNRTGVSK
10 20 30
90 100 110 120 130 140
pF1KE0 GYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQ
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE0 NVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAF
::::::::::::::::::::::::::
XP_011 NVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWVLPEG
100 110 120 130 140 150
>>NP_004072 (OMIM: 400003,415000) deleted in azoospermia (744 aa)
initn: 2660 init1: 2589 opt: 2600 Z-score: 1545.3 bits: 295.8 E(85289): 2.5e-79
Smith-Waterman score: 2819; 93.4% identity (94.1% similar) in 437 aa overlap (2-438:332-744)
10 20 30
pF1KE0 MSAANPETPNSTISREASTQSSSAAASQGWV
::::::::::::::::::::::::::::::
NP_004 PQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWV
310 320 330 340 350 360
40 50 60 70 80 90
pF1KE0 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
370 380 390 400 410 420
100 110 120 130 140 150
pF1KE0 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
430 440 450 460 470 480
160 170 180 190 200 210
pF1KE0 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
490 500 510 520 530 540
220 230 240 250 260 270
pF1KE0 NYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSP
::::::::::::::::::::::::::::::::::::::::::::::::::: :::::.::
NP_004 NYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSP
550 560 570 580 590 600
280 290 300 310 320 330
pF1KE0 VQVTTGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVY
:::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVY
610 620 630 640 650 660
340 350 360 370 380 390
pF1KE0 NYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSA
:::::::::.::::: :::::::::::::::::::::
NP_004 NYQAFPAYPSSPFQV------------------------TTGYQLPVYNYQAFPAYPNSA
670 680 690
400 410 420 430
pF1KE0 VQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
:::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
700 710 720 730 740
>--
initn: 1142 init1: 1126 opt: 1147 Z-score: 695.1 bits: 138.5 E(85289): 5.6e-32
Smith-Waterman score: 1147; 94.4% identity (98.9% similar) in 180 aa overlap (1-180:1-179)
10 20 30 40 50 60
pF1KE0 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
::::::::::::::::::::::::::::::::::::::::::::::. .: :..:...:.
NP_004 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQS-AANPETPNSTIS
130 140 150 160 170
190 200 210 220 230 240
pF1KE0 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
NP_004 REASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITN
180 190 200 210 220 230
>--
initn: 1038 init1: 1038 opt: 1038 Z-score: 631.3 bits: 126.7 E(85289): 2e-28
Smith-Waterman score: 1038; 100.0% identity (100.0% similar) in 152 aa overlap (15-166:180-331)
10 20 30 40
pF1KE0 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFV
::::::::::::::::::::::::::::::
NP_004 TYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFV
150 160 170 180 190 200
50 60 70 80 90 100
pF1KE0 GGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFH
210 220 230 240 250 260
110 120 130 140 150 160
pF1KE0 GKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQH
270 280 290 300 310 320
170 180 190 200 210 220
pF1KE0 VQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPF
::
NP_004 VQSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSC
330 340 350 360 370 380
>>NP_001005786 (OMIM: 400026,415000) deleted in azoosper (366 aa)
initn: 2239 init1: 2239 opt: 2250 Z-score: 1343.6 bits: 257.5 E(85289): 4.2e-68
Smith-Waterman score: 2373; 82.0% identity (83.1% similar) in 438 aa overlap (1-438:1-366)
10 20 30 40 50 60
pF1KE0 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
NP_001 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVAT
::::.:::::
NP_001 PAYPSSPFQV--------------------------------------------------
250
310 320 330 340 350 360
pF1KE0 GYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAF
::::::::::::::::::.:::::.::::.::::::::
NP_001 ----------------------TTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAF
260 270 280
370 380 390 400 410 420
pF1KE0 PAYPNSPVQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNL
::::.:: ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAYPSSPFQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNL
290 300 310 320 330 340
430
pF1KE0 WTEAYKWWYLVCLIQRRD
::::::::::::::::::
NP_001 WTEAYKWWYLVCLIQRRD
350 360
>>NP_001342 (OMIM: 601486) deleted in azoospermia-like i (295 aa)
initn: 1061 init1: 1061 opt: 1077 Z-score: 658.2 bits: 130.3 E(85289): 6.4e-30
Smith-Waterman score: 1077; 82.7% identity (90.8% similar) in 196 aa overlap (1-196:1-196)
10 20 30 40 50 60
pF1KE0 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
::.::::::::::::::::::::::.:::..::::::.::::::::::.::::::: : :
NP_001 MSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
.::::::::::::.::::::::::::: ::::::::: :::.:::::::::::::::.::
NP_001 ARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
: :::::::: : :::::::::: :::::::.:: : ::.::.:::: .::.:: ::::
NP_001 AYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
: :: ::::: : .:
NP_001 GYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSG
190 200 210 220 230 240
>>NP_001177740 (OMIM: 601486) deleted in azoospermia-lik (315 aa)
initn: 1054 init1: 1054 opt: 1070 Z-score: 653.8 bits: 129.6 E(85289): 1.1e-29
Smith-Waterman score: 1070; 82.6% identity (90.8% similar) in 195 aa overlap (2-196:22-216)
10 20 30 40
pF1KE0 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPN
:.::::::::::::::::::::::.:::..::::::.::
NP_001 MAAPSCGGDRKARLTPSLPHESTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPN
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 TVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQ
::::::::.::::::: : :.::::::::::::.::::::::::::: ::::::::: ::
NP_001 TVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQ
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 IHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNP
:.:::::::::::::::.::: :::::::: : :::::::::: :::::::.:: : ::
NP_001 INFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNP
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 VTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYP
.::.:::: .::.:: ::::: :: ::::: : .:
NP_001 ITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVD
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 RSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQL
NP_001 PGAEVVPNECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFNPENRLRNSVVTQDDYFKDK
250 260 270 280 290 300
>>NP_149019 (OMIM: 606165) protein boule-like isoform 2 (283 aa)
initn: 397 init1: 257 opt: 336 Z-score: 224.8 bits: 50.1 E(85289): 8.8e-06
Smith-Waterman score: 340; 31.1% identity (54.5% similar) in 264 aa overlap (35-289:28-274)
10 20 30 40 50 60
pF1KE0 NPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYG
: ..:: .:::::: . .:... . :..::
NP_149 MQTDSLSPSPNPVSPVPLNNPTSAPRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYG
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIV--GSQIHFHGKKLKLGPAIRKQKLCAR
:::::::...:.:::::::::.: .. :.:::. . ..... :::..:::::::..
NP_149 SVKEVKIVNDRAGVSKGYGFVTFETQEDAQKILQEAEKLNYKDKKLNIGPAIRKQQVGI-
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 HVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQ-HVQAYSAYPHSPGQVITG
:: .. : .. : . : : :. :. .. : : .
NP_149 ---PRSSIM-PAAGTMYL-------TTSTGYPYTYHNGVAYFHTPEVTSVP-PPWPSRSV
120 130 140 150 160
190 200 210 220 230
pF1KE0 CQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQ---PFPAYPRSPF---QVTAGYQLPVY
:. :. : : .:.:: : :: ..: : :. .:: : . ::
NP_149 CSSPVMVAQPIYQQPAYHYQATTQY-LP-GQWQWSVPQPSASSAPFLYLQPSEVIYQPVE
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 NYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSP
: : . :. : .. . .: . : . .. .:. .: :
NP_149 IAQDGGCVPPPLSLMETSVPEPYSDHGVQATYHQ--VYAPSAITMPAPVMQPEPIKTVWS
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE0 FQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVATGYQFPVY
NP_149 IHY
438 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:52:55 2016 done: Tue Nov 8 01:52:57 2016
Total Scan time: 7.540 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]