Result of FASTA (omim) for
pFN21AE0718
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0718, 414 aa
1>>>pF1KE0718 414 - 414 aa - 414 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.9531+/-0.000431; mu= 2.5541+/- 0.027
mean_var=481.1626+/-108.829, 0's: 0 Z-trim(121.3): 1742 B-trim: 0 in 0/54
Lambda= 0.058469
statistics sampled from 35343 (37805) to 35343 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.443), width: 16
Scan time: 9.950
The best scores are: opt bits E(85289)
NP_004751 (OMIM: 604726) serine/threonine-protein ( 414) 2720 244.1 4.9e-64
XP_016868281 (OMIM: 604726) PREDICTED: serine/thre ( 323) 2084 190.2 6.1e-48
XP_011510472 (OMIM: 604727) PREDICTED: serine/thre ( 372) 1230 118.3 3.2e-26
XP_011510471 (OMIM: 604727) PREDICTED: serine/thre ( 372) 1230 118.3 3.2e-26
XP_011510470 (OMIM: 604727) PREDICTED: serine/thre ( 372) 1230 118.3 3.2e-26
NP_004217 (OMIM: 604727) serine/threonine-protein ( 372) 1230 118.3 3.2e-26
NP_001339 (OMIM: 603289) death-associated protein ( 454) 856 86.9 1.1e-16
XP_005259565 (OMIM: 603289) PREDICTED: death-assoc ( 454) 856 86.9 1.1e-16
XP_016877533 (OMIM: 616567) PREDICTED: death-assoc ( 350) 852 86.4 1.2e-16
NP_055141 (OMIM: 616567) death-associated protein ( 370) 852 86.4 1.3e-16
XP_011519716 (OMIM: 616567) PREDICTED: death-assoc ( 380) 852 86.4 1.3e-16
XP_011519715 (OMIM: 616567) PREDICTED: death-assoc ( 389) 852 86.5 1.3e-16
XP_005251814 (OMIM: 600831) PREDICTED: death-assoc ( 839) 857 87.4 1.4e-16
NP_001275660 (OMIM: 600831) death-associated prote (1430) 857 87.8 1.9e-16
NP_004929 (OMIM: 600831) death-associated protein (1430) 857 87.8 1.9e-16
NP_001275658 (OMIM: 600831) death-associated prote (1430) 857 87.8 1.9e-16
NP_001275659 (OMIM: 600831) death-associated prote (1430) 857 87.8 1.9e-16
XP_011519717 (OMIM: 616567) PREDICTED: death-assoc ( 359) 842 85.6 2.2e-16
XP_011519718 (OMIM: 616567) PREDICTED: death-assoc ( 488) 843 85.9 2.5e-16
XP_016877534 (OMIM: 616567) PREDICTED: death-assoc ( 316) 781 80.3 7.4e-15
XP_016877535 (OMIM: 616567) PREDICTED: death-assoc ( 316) 781 80.3 7.4e-15
XP_011519719 (OMIM: 616567) PREDICTED: death-assoc ( 316) 781 80.3 7.4e-15
XP_011510473 (OMIM: 604727) PREDICTED: serine/thre ( 244) 759 78.3 2.3e-14
XP_006721397 (OMIM: 612147) PREDICTED: myosin ligh ( 478) 726 76.0 2.3e-13
NP_001295230 (OMIM: 612147) myosin light chain kin ( 478) 726 76.0 2.3e-13
NP_872299 (OMIM: 612147) myosin light chain kinase ( 819) 726 76.3 3e-13
NP_149109 (OMIM: 192600,606566) myosin light chain ( 596) 721 75.7 3.4e-13
XP_016861959 (OMIM: 600922,613780) PREDICTED: myos ( 713) 699 74.0 1.4e-12
XP_016861960 (OMIM: 600922,613780) PREDICTED: myos ( 714) 699 74.0 1.4e-12
XP_016861958 (OMIM: 600922,613780) PREDICTED: myos ( 991) 699 74.2 1.6e-12
NP_001308238 (OMIM: 600922,613780) myosin light ch (1738) 699 74.6 2.2e-12
NP_444254 (OMIM: 600922,613780) myosin light chain (1845) 699 74.6 2.2e-12
XP_011511162 (OMIM: 600922,613780) PREDICTED: myos (1913) 699 74.6 2.3e-12
NP_444253 (OMIM: 600922,613780) myosin light chain (1914) 699 74.6 2.3e-12
NP_001309922 (OMIM: 604605,608901) kalirin isoform (1288) 685 73.2 4.2e-12
NP_008995 (OMIM: 604605,608901) kalirin isoform 3 (1289) 685 73.2 4.2e-12
XP_016862919 (OMIM: 604605,608901) PREDICTED: kali (2955) 685 73.8 6.5e-12
XP_006713877 (OMIM: 604605,608901) PREDICTED: kali (2956) 685 73.8 6.5e-12
XP_006713876 (OMIM: 604605,608901) PREDICTED: kali (2966) 685 73.8 6.5e-12
XP_016862918 (OMIM: 604605,608901) PREDICTED: kali (2968) 685 73.8 6.5e-12
XP_006713875 (OMIM: 604605,608901) PREDICTED: kali (2975) 685 73.8 6.5e-12
XP_011511583 (OMIM: 604605,608901) PREDICTED: kali (2977) 685 73.8 6.5e-12
XP_006713874 (OMIM: 604605,608901) PREDICTED: kali (2979) 685 73.8 6.5e-12
NP_001019831 (OMIM: 604605,608901) kalirin isoform (2986) 685 73.8 6.6e-12
XP_011511581 (OMIM: 604605,608901) PREDICTED: kali (2987) 685 73.8 6.6e-12
XP_011511582 (OMIM: 604605,608901) PREDICTED: kali (2987) 685 73.8 6.6e-12
XP_006713873 (OMIM: 604605,608901) PREDICTED: kali (2988) 685 73.8 6.6e-12
NP_003310 (OMIM: 188840,600334,603689,604145,60880 (26926) 663 73.4 7.5e-11
XP_016860312 (OMIM: 188840,600334,603689,604145,60 (26973) 663 73.4 7.5e-11
NP_597676 (OMIM: 188840,600334,603689,604145,60880 (27051) 663 73.4 7.5e-11
>>NP_004751 (OMIM: 604726) serine/threonine-protein kina (414 aa)
initn: 2720 init1: 2720 opt: 2720 Z-score: 1270.6 bits: 244.1 E(85289): 4.9e-64
Smith-Waterman score: 2720; 99.8% identity (100.0% similar) in 414 aa overlap (1-414:1-414)
10 20 30 40 50 60
pF1KE0 MIPLEKPGSGGSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAVVRTEPFQDGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MIPLEKPGSGGSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAVVRTEPFQDGYS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LCPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LCPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VINLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VINLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SMATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SMATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LLVKKPEDRATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLVKKPEDRATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSE
310 320 330 340 350 360
370 380 390 400 410
pF1KE0 TEESIVTEELIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY
:.::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TKESIVTEELIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY
370 380 390 400 410
>>XP_016868281 (OMIM: 604726) PREDICTED: serine/threonin (323 aa)
initn: 2084 init1: 2084 opt: 2084 Z-score: 981.7 bits: 190.2 E(85289): 6.1e-48
Smith-Waterman score: 2084; 99.7% identity (100.0% similar) in 323 aa overlap (92-414:1-323)
70 80 90 100 110 120
pF1KE0 CPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWV
::::::::::::::::::::::::::::::
XP_016 MRKRRKGQDCRMEIIHEIAVLELAQDNPWV
10 20 30
130 140 150 160 170 180
pF1KE0 INLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRD
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE0 VVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPIS
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE0 MATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTL
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE0 LVKKPEDRATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVKKPEDRATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSET
220 230 240 250 260 270
370 380 390 400 410
pF1KE0 EESIVTEELIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY
.::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KESIVTEELIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY
280 290 300 310 320
>>XP_011510472 (OMIM: 604727) PREDICTED: serine/threonin (372 aa)
initn: 1259 init1: 1202 opt: 1230 Z-score: 591.8 bits: 118.3 E(85289): 3.2e-26
Smith-Waterman score: 1247; 54.1% identity (77.2% similar) in 377 aa overlap (41-413:13-367)
20 30 40 50 60
pF1KE0 GSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAV-VRTEPFQDGYSLCPGRELGR
:::: . .. : :.. : : ..::::
XP_011 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILT-SKELGR
10 20 30 40
70 80 90 100 110 120
pF1KE0 GKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVINLHEVYE
:::::::.::.:..:.:.::::..:::.::::: ::.:::::::::.. : :::::::::
XP_011 GKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 TASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKP
..::.::.::::::::::. :. . : .:.:: ::..::::::..:: ..:::::::
XP_011 NTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 QNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSI
:::::.: :::::::::::.:: . .. :::::::::::.:::::.::::. :::::.:
XP_011 QNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 GVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDR
:...:..:: :::.:.:.:::.:::::.:..:::: :. .:. :.:::..::::.:: :
XP_011 GIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKR
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE0 ATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSETEESIVTEE
::: ::.: :: : .. : :. :.. ... . ::: .. :.:: .
XP_011 PTAEICLSHSWLQQWDF-ENLFHPEET--SSSSQTQDHSVRSSEDKTSKSSCN-------
290 300 310 320 330
370 380 390 400 410
pF1KE0 LIVVTSYTLGQCRQSE-KEKMEQKA--ISKRFKFEEPLLQEIPGEFIY
: : . : ::.. . . .::::.:.. : : :..
XP_011 ---------GTCGDREDKENIPEDSSMVSKRFRFDDSL--PNPHELVSDLLC
340 350 360 370
>>XP_011510471 (OMIM: 604727) PREDICTED: serine/threonin (372 aa)
initn: 1259 init1: 1202 opt: 1230 Z-score: 591.8 bits: 118.3 E(85289): 3.2e-26
Smith-Waterman score: 1247; 54.1% identity (77.2% similar) in 377 aa overlap (41-413:13-367)
20 30 40 50 60
pF1KE0 GSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAV-VRTEPFQDGYSLCPGRELGR
:::: . .. : :.. : : ..::::
XP_011 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILT-SKELGR
10 20 30 40
70 80 90 100 110 120
pF1KE0 GKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVINLHEVYE
:::::::.::.:..:.:.::::..:::.::::: ::.:::::::::.. : :::::::::
XP_011 GKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 TASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKP
..::.::.::::::::::. :. . : .:.:: ::..::::::..:: ..:::::::
XP_011 NTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 QNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSI
:::::.: :::::::::::.:: . .. :::::::::::.:::::.::::. :::::.:
XP_011 QNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 GVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDR
:...:..:: :::.:.:.:::.:::::.:..:::: :. .:. :.:::..::::.:: :
XP_011 GIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKR
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE0 ATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSETEESIVTEE
::: ::.: :: : .. : :. :.. ... . ::: .. :.:: .
XP_011 PTAEICLSHSWLQQWDF-ENLFHPEET--SSSSQTQDHSVRSSEDKTSKSSCN-------
290 300 310 320 330
370 380 390 400 410
pF1KE0 LIVVTSYTLGQCRQSE-KEKMEQKA--ISKRFKFEEPLLQEIPGEFIY
: : . : ::.. . . .::::.:.. : : :..
XP_011 ---------GTCGDREDKENIPEDSSMVSKRFRFDDSL--PNPHELVSDLLC
340 350 360 370
>>XP_011510470 (OMIM: 604727) PREDICTED: serine/threonin (372 aa)
initn: 1259 init1: 1202 opt: 1230 Z-score: 591.8 bits: 118.3 E(85289): 3.2e-26
Smith-Waterman score: 1247; 54.1% identity (77.2% similar) in 377 aa overlap (41-413:13-367)
20 30 40 50 60
pF1KE0 GSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAV-VRTEPFQDGYSLCPGRELGR
:::: . .. : :.. : : ..::::
XP_011 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILT-SKELGR
10 20 30 40
70 80 90 100 110 120
pF1KE0 GKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVINLHEVYE
:::::::.::.:..:.:.::::..:::.::::: ::.:::::::::.. : :::::::::
XP_011 GKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 TASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKP
..::.::.::::::::::. :. . : .:.:: ::..::::::..:: ..:::::::
XP_011 NTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 QNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSI
:::::.: :::::::::::.:: . .. :::::::::::.:::::.::::. :::::.:
XP_011 QNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 GVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDR
:...:..:: :::.:.:.:::.:::::.:..:::: :. .:. :.:::..::::.:: :
XP_011 GIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKR
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE0 ATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSETEESIVTEE
::: ::.: :: : .. : :. :.. ... . ::: .. :.:: .
XP_011 PTAEICLSHSWLQQWDF-ENLFHPEET--SSSSQTQDHSVRSSEDKTSKSSCN-------
290 300 310 320 330
370 380 390 400 410
pF1KE0 LIVVTSYTLGQCRQSE-KEKMEQKA--ISKRFKFEEPLLQEIPGEFIY
: : . : ::.. . . .::::.:.. : : :..
XP_011 ---------GTCGDREDKENIPEDSSMVSKRFRFDDSL--PNPHELVSDLLC
340 350 360 370
>>NP_004217 (OMIM: 604727) serine/threonine-protein kina (372 aa)
initn: 1259 init1: 1202 opt: 1230 Z-score: 591.8 bits: 118.3 E(85289): 3.2e-26
Smith-Waterman score: 1247; 54.1% identity (77.2% similar) in 377 aa overlap (41-413:13-367)
20 30 40 50 60
pF1KE0 GSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAV-VRTEPFQDGYSLCPGRELGR
:::: . .. : :.. : : ..::::
NP_004 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILT-SKELGR
10 20 30 40
70 80 90 100 110 120
pF1KE0 GKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVINLHEVYE
:::::::.::.:..:.:.::::..:::.::::: ::.:::::::::.. : :::::::::
NP_004 GKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 TASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKP
..::.::.::::::::::. :. . : .:.:: ::..::::::..:: ..:::::::
NP_004 NTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 QNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSI
:::::.: :::::::::::.:: . .. :::::::::::.:::::.::::. :::::.:
NP_004 QNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 GVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDR
:...:..:: :::.:.:.:::.:::::.:..:::: :. .:. :.:::..::::.:: :
NP_004 GIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKR
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE0 ATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSETEESIVTEE
::: ::.: :: : .. : :. :.. ... . ::: .. :.:: .
NP_004 PTAEICLSHSWLQQWDF-ENLFHPEET--SSSSQTQDHSVRSSEDKTSKSSCN-------
290 300 310 320 330
370 380 390 400 410
pF1KE0 LIVVTSYTLGQCRQSE-KEKMEQKA--ISKRFKFEEPLLQEIPGEFIY
: : . : ::.. . . .::::.:.. : : :..
NP_004 ---------GTCGDREDKENIPEDSSMVSKRFRFDDSL--PNPHELVSDLLC
340 350 360 370
>>NP_001339 (OMIM: 603289) death-associated protein kina (454 aa)
initn: 880 init1: 454 opt: 856 Z-score: 420.4 bits: 86.9 E(85289): 1.1e-16
Smith-Waterman score: 865; 41.4% identity (73.4% similar) in 338 aa overlap (51-369:5-337)
30 40 50 60 70 80
pF1KE0 GRAGRGLSGPCRPPPPPQARGLLTEIRAVVRTEPFQDGYSLCPGRELGRGKFAVVRKCIK
: : .: : . :.::: :.::.:::: .
NP_001 MSTFRQEDVEDHYEM--GEELGSGQFAIVRKCRQ
10 20 30
90 100 110 120 130
pF1KE0 KDSGKEFAAKFMRKRRKGQD----CRMEIIHEIAVLELAQDNPWVINLHEVYETASEMIL
: .:::.::::..::: ... : :: .:. .:. . .: .:.::...:. ....:
NP_001 KGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIR-HPNIITLHDIFENKTDVVL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE0 VLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTS
.:: ..:::.:: .:..: .. : .. ....:::.:::.::.. ..:.::::.::.: .
NP_001 ILELVSGGELFD-FLAEKE-SLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLD
100 110 120 130 140
200 210 220 230 240 250
pF1KE0 ES-PLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGVLTYV
.. : ::..:::... .. ..:...:.::::.:::::..:.:... .:::::::.::.
NP_001 KNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYI
150 160 170 180 190 200
260 270 280 290 300 310
pF1KE0 MLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEEC
.:.: :::::. ::::. ::: .: ...:: :. :: : :::: :::: :. : : .
NP_001 LLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRRMTIAQS
210 220 230 240 250 260
320 330 340 350 360
pF1KE0 LKHPWLT---------QSSIQEPSFRMEKALEEANALQEGHS-VPEINSDTD----KSET
:.: :. ..: ..: : :. . . ..:: .: :: .: ..
NP_001 LEHSWIKAIRRRNVRGEDSGRKPERRRLKTTRLKEYTIKSHSSLPPNNSYADFERFSKVL
270 280 290 300 310 320
370 380 390 400 410
pF1KE0 EESIVTEELIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY
::. ..::
NP_001 EEAAAAEEGLRELQRSRRLCHEDVEALAAIYEEKEAWYREESDSLGQDLRRLRQELLKTE
330 340 350 360 370 380
>>XP_005259565 (OMIM: 603289) PREDICTED: death-associate (454 aa)
initn: 880 init1: 454 opt: 856 Z-score: 420.4 bits: 86.9 E(85289): 1.1e-16
Smith-Waterman score: 865; 41.4% identity (73.4% similar) in 338 aa overlap (51-369:5-337)
30 40 50 60 70 80
pF1KE0 GRAGRGLSGPCRPPPPPQARGLLTEIRAVVRTEPFQDGYSLCPGRELGRGKFAVVRKCIK
: : .: : . :.::: :.::.:::: .
XP_005 MSTFRQEDVEDHYEM--GEELGSGQFAIVRKCRQ
10 20 30
90 100 110 120 130
pF1KE0 KDSGKEFAAKFMRKRRKGQD----CRMEIIHEIAVLELAQDNPWVINLHEVYETASEMIL
: .:::.::::..::: ... : :: .:. .:. . .: .:.::...:. ....:
XP_005 KGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIR-HPNIITLHDIFENKTDVVL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE0 VLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTS
.:: ..:::.:: .:..: .. : .. ....:::.:::.::.. ..:.::::.::.: .
XP_005 ILELVSGGELFD-FLAEKE-SLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLD
100 110 120 130 140
200 210 220 230 240 250
pF1KE0 ES-PLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGVLTYV
.. : ::..:::... .. ..:...:.::::.:::::..:.:... .:::::::.::.
XP_005 KNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYI
150 160 170 180 190 200
260 270 280 290 300 310
pF1KE0 MLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEEC
.:.: :::::. ::::. ::: .: ...:: :. :: : :::: :::: :. : : .
XP_005 LLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRRMTIAQS
210 220 230 240 250 260
320 330 340 350 360
pF1KE0 LKHPWLT---------QSSIQEPSFRMEKALEEANALQEGHS-VPEINSDTD----KSET
:.: :. ..: ..: : :. . . ..:: .: :: .: ..
XP_005 LEHSWIKAIRRRNVRGEDSGRKPERRRLKTTRLKEYTIKSHSSLPPNNSYADFERFSKVL
270 280 290 300 310 320
370 380 390 400 410
pF1KE0 EESIVTEELIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY
::. ..::
XP_005 EEAAAAEEGLRELQRSRRLCHEDVEALAAIYEEKEAWYREESDSLGQDLRRLRQELLKTE
330 340 350 360 370 380
>>XP_016877533 (OMIM: 616567) PREDICTED: death-associate (350 aa)
initn: 831 init1: 468 opt: 852 Z-score: 419.7 bits: 86.4 E(85289): 1.2e-16
Smith-Waterman score: 852; 44.0% identity (77.7% similar) in 300 aa overlap (53-341:12-305)
30 40 50 60 70
pF1KE0 AGRGLSGPCRPPPPPQARGLLTEIRAVVRTEPFQ-----DGYSLCPGRELGRGKFAVVRK
:::. : :.. :.::: :.::.:.:
XP_016 MFQASMRSPNMEPFKQQKVEDFYDI--GEELGSGQFAIVKK
10 20 30
80 90 100 110 120 130
pF1KE0 CIKKDSGKEFAAKFMRKR-----RKGQDCRMEIIHEIAVLELAQDNPWVINLHEVYETAS
: .:..: :.::::..:: :.: . : :: .:...:. . . ::.::.:::. .
XP_016 CREKSTGLEYAAKFIKKRQSRASRRGVS-REEIEREVSILRQVLHHN-VITLHDVYENRT
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE0 EMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQNI
...:.:: ..:::.:: ..:...:... ...:::.::..:::. ..:.::::.::
XP_016 DVVLILELVSGGELFD--FLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENI
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE0 LLTSES-PLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGV
.: ... :. ::..::::.. .... :...:.::::.:::::..:.:... .:::::::
XP_016 MLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGV
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE0 LTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRAT
.::..:.: :::::. ::::. ::. .. ...:: :. :: : :::: ::::. . : :
XP_016 ITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLT
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE0 AEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSETEESIVTEELI
.: :.:::.: . :. : :.... :
XP_016 IQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSFSIVSLCNHLTRSLMKK
280 290 300 310 320 330
>>NP_055141 (OMIM: 616567) death-associated protein kina (370 aa)
initn: 831 init1: 468 opt: 852 Z-score: 419.5 bits: 86.4 E(85289): 1.3e-16
Smith-Waterman score: 852; 44.0% identity (77.7% similar) in 300 aa overlap (53-341:12-305)
30 40 50 60 70
pF1KE0 AGRGLSGPCRPPPPPQARGLLTEIRAVVRTEPFQ-----DGYSLCPGRELGRGKFAVVRK
:::. : :.. :.::: :.::.:.:
NP_055 MFQASMRSPNMEPFKQQKVEDFYDI--GEELGSGQFAIVKK
10 20 30
80 90 100 110 120 130
pF1KE0 CIKKDSGKEFAAKFMRKR-----RKGQDCRMEIIHEIAVLELAQDNPWVINLHEVYETAS
: .:..: :.::::..:: :.: . : :: .:...:. . . ::.::.:::. .
NP_055 CREKSTGLEYAAKFIKKRQSRASRRGVS-REEIEREVSILRQVLHHN-VITLHDVYENRT
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE0 EMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQNI
...:.:: ..:::.:: ..:...:... ...:::.::..:::. ..:.::::.::
NP_055 DVVLILELVSGGELFD--FLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENI
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE0 LLTSES-PLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGV
.: ... :. ::..::::.. .... :...:.::::.:::::..:.:... .:::::::
NP_055 MLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGV
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE0 LTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRAT
.::..:.: :::::. ::::. ::. .. ...:: :. :: : :::: ::::. . : :
NP_055 ITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLT
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE0 AEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSETEESIVTEELI
.: :.:::.: . :. : :.... :
NP_055 IQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSFSIVSLCNHLTRSLMKK
280 290 300 310 320 330
414 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:50:00 2016 done: Sun Nov 6 05:50:01 2016
Total Scan time: 9.950 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]