Result of FASTA (omim) for
pFN21AE0714
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0714, 411 aa
1>>>pF1KE0714 411 - 411 aa - 411 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.8439+/-0.000578; mu= -16.9059+/- 0.036
mean_var=852.2665+/-178.772, 0's: 0 Z-trim(123.0): 419 B-trim: 699 in 1/60
Lambda= 0.043933
statistics sampled from 41490 (41990) to 41490 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.756), E-opt: 0.2 (0.492), width: 16
Scan time: 7.370
The best scores are: opt bits E(85289)
NP_940881 (OMIM: 611166) tetra-peptide repeat home ( 411) 3021 206.5 1e-52
XP_016857330 (OMIM: 606373,616193) PREDICTED: form (1102) 555 50.7 2e-05
XP_016857329 (OMIM: 606373,616193) PREDICTED: form (1102) 555 50.7 2e-05
XP_016857328 (OMIM: 606373,616193) PREDICTED: form (1159) 555 50.8 2.1e-05
XP_011542539 (OMIM: 606373,616193) PREDICTED: form (1360) 555 50.9 2.3e-05
XP_016857327 (OMIM: 606373,616193) PREDICTED: form (1384) 555 50.9 2.4e-05
XP_016857326 (OMIM: 606373,616193) PREDICTED: form (1417) 555 50.9 2.4e-05
NP_064450 (OMIM: 606373,616193) formin-2 isoform 2 (1722) 555 51.0 2.7e-05
NP_001292353 (OMIM: 606373,616193) formin-2 isofor (1726) 555 51.0 2.7e-05
XP_016884752 (OMIM: 301050,303630) PREDICTED: coll (1136) 478 45.9 0.00061
XP_016867496 (OMIM: 604918,608027) PREDICTED: prot (2561) 488 47.0 0.00065
XP_016884751 (OMIM: 301050,303630) PREDICTED: coll (1289) 478 46.0 0.00066
XP_016884750 (OMIM: 301050,303630) PREDICTED: coll (1330) 478 46.0 0.00068
XP_016867495 (OMIM: 604918,608027) PREDICTED: prot (2838) 488 47.0 0.00069
NP_000486 (OMIM: 301050,303630) collagen alpha-5(I (1685) 478 46.1 0.00078
XP_016884749 (OMIM: 301050,303630) PREDICTED: coll (1690) 478 46.1 0.00078
NP_203699 (OMIM: 301050,303630) collagen alpha-5(I (1691) 478 46.1 0.00078
XP_016884748 (OMIM: 301050,303630) PREDICTED: coll (1693) 478 46.1 0.00078
XP_011529151 (OMIM: 301050,303630) PREDICTED: coll (1696) 478 46.1 0.00078
NP_055325 (OMIM: 604918,608027) protein piccolo is (4935) 488 47.3 0.00097
NP_149015 (OMIM: 604918,608027) protein piccolo is (5142) 488 47.4 0.00099
XP_011508874 (OMIM: 120131,203780) PREDICTED: coll (1132) 448 44.0 0.0023
XP_005262513 (OMIM: 300688) PREDICTED: BCL-6 corep (1655) 453 44.5 0.0023
XP_006724842 (OMIM: 300688) PREDICTED: BCL-6 corep (1687) 453 44.5 0.0023
NP_068765 (OMIM: 300688) BCL-6 corepressor-like pr (1711) 453 44.5 0.0024
NP_001171701 (OMIM: 300688) BCL-6 corepressor-like (1785) 453 44.6 0.0024
XP_005262511 (OMIM: 300688) PREDICTED: BCL-6 corep (1785) 453 44.6 0.0024
XP_006724839 (OMIM: 300688) PREDICTED: BCL-6 corep (1785) 453 44.6 0.0024
XP_006724840 (OMIM: 300688) PREDICTED: BCL-6 corep (1785) 453 44.6 0.0024
XP_005262510 (OMIM: 300688) PREDICTED: BCL-6 corep (1785) 453 44.6 0.0024
XP_016885211 (OMIM: 300688) PREDICTED: BCL-6 corep (1785) 453 44.6 0.0024
XP_005262509 (OMIM: 300688) PREDICTED: BCL-6 corep (1785) 453 44.6 0.0024
XP_016885210 (OMIM: 300688) PREDICTED: BCL-6 corep (1785) 453 44.6 0.0024
XP_005262512 (OMIM: 300688) PREDICTED: BCL-6 corep (1785) 453 44.6 0.0024
XP_011508860 (OMIM: 120131,203780) PREDICTED: coll (1654) 448 44.2 0.0029
XP_011533734 (OMIM: 120110,156500) PREDICTED: coll ( 680) 429 42.5 0.0039
XP_011533735 (OMIM: 120110,156500) PREDICTED: coll ( 680) 429 42.5 0.0039
XP_016865737 (OMIM: 120110,156500) PREDICTED: coll ( 680) 429 42.5 0.0039
NP_000484 (OMIM: 120110,156500) collagen alpha-1(X ( 680) 429 42.5 0.0039
XP_006715396 (OMIM: 120110,156500) PREDICTED: coll ( 680) 429 42.5 0.0039
XP_016865738 (OMIM: 120110,156500) PREDICTED: coll ( 680) 429 42.5 0.0039
NP_001281276 (OMIM: 120252,136800,609140) collagen ( 638) 428 42.4 0.0039
NP_005193 (OMIM: 120252,136800,609140) collagen al ( 703) 428 42.4 0.0041
XP_005270534 (OMIM: 120252,136800,609140) PREDICTE ( 780) 428 42.5 0.0044
NP_000485 (OMIM: 113811,122400,226650) collagen al (1497) 437 43.4 0.0044
NP_008938 (OMIM: 604979) cleavage and polyadenylat ( 551) 423 42.0 0.0044
XP_005268647 (OMIM: 604979) PREDICTED: cleavage an ( 552) 423 42.0 0.0044
XP_011536691 (OMIM: 601234) PREDICTED: nascent pol (2078) 435 43.5 0.0059
XP_006719477 (OMIM: 601234) PREDICTED: nascent pol (2082) 435 43.5 0.0059
XP_006719475 (OMIM: 601234) PREDICTED: nascent pol (2082) 435 43.5 0.0059
>>NP_940881 (OMIM: 611166) tetra-peptide repeat homeobox (411 aa)
initn: 3021 init1: 3021 opt: 3021 Z-score: 1067.6 bits: 206.5 E(85289): 1e-52
Smith-Waterman score: 3021; 100.0% identity (100.0% similar) in 411 aa overlap (1-411:1-411)
10 20 30 40 50 60
pF1KE0 MLSLREQQLQVWFKNRRAKLARERRLQQQPQRVPGQRGRGARAAPLVPAASASAPQRGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 MLSLREQQLQVWFKNRRAKLARERRLQQQPQRVPGQRGRGARAAPLVPAASASAPQRGPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GILPAAEPTICSLHQAWGGPGCRAQKGIPAALSPGPGPIPAPIPGPAQIPGPLPGSIPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 GILPAAEPTICSLHQAWGGPGCRAQKGIPAALSPGPGPIPAPIPGPAQIPGPLPGSIPGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IPGPAQIPSPIPAPIPGPISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 IPGPAQIPSPIPAPIPGPISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GPNPGPIPGPISGPIPGPISVPIPGPIPGPISGPISGPNPGPIPGPIPGPISGPNPGPIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 GPNPGPIPGPISGPIPGPISVPIPGPIPGPISGPISGPNPGPIPGPIPGPISGPNPGPIP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 GPISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQIPGPGRLQGPGPILSPGRMRSPGSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 GPISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQIPGPGRLQGPGPILSPGRMRSPGSLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 GLAPILGPGSGPGSGSVPAPIPGPGSLPAPAPLWPQSPDASDFLPDTQLFPHFTELLLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 GLAPILGPGSGPGSGSVPAPIPGPGSLPAPAPLWPQSPDASDFLPDTQLFPHFTELLLPL
310 320 330 340 350 360
370 380 390 400 410
pF1KE0 DPLEGSSVSTMTSQYQEGDDSMGKKHSGSQPQEEGGSVNENHSGPRLLLDL
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 DPLEGSSVSTMTSQYQEGDDSMGKKHSGSQPQEEGGSVNENHSGPRLLLDL
370 380 390 400 410
>>XP_016857330 (OMIM: 606373,616193) PREDICTED: formin-2 (1102 aa)
initn: 497 init1: 307 opt: 555 Z-score: 218.2 bits: 50.7 E(85289): 2e-05
Smith-Waterman score: 644; 37.0% identity (48.7% similar) in 392 aa overlap (30-367:260-632)
10 20 30 40 50
pF1KE0 MLSLREQQLQVWFKNRRAKLARERRLQQQPQRVPGQRGRGARAAPLVPAASASAPQRGP
: .::. ..: .: :.. :: :
XP_016 KNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGM------TVPTLP--STAIPQPPP
230 240 250 260 270 280
60 70 80 90 100 110
pF1KE0 ---SGILPAAEPTICSLH----QAWGGPGCRAQKGIPAALSPGPGPIP-APIPGPAQIPG
. .:: : . . : : .:.: : : :.: : :: : .::
XP_016 LQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG
290 300 310 320 330 340
120 130 140 150
pF1KE0 ---PLPGSIPGP-IPGPAQIPS---PIPAPIPGP-ISGPVQIPG---PFRGPIPGP-ISG
::: .:: :: : .:. : : :.:: : : .:: : :.:: :
XP_016 AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP
350 360 370 380 390 400
160 170 180 190 200
pF1KE0 PAPIPG---PISGPFSG---PNPGPIPG---PNPGPIPG---PISGPIPGPISVPIPGPI
: :.:: : :. : : : :.:: : : :.:: : :.:: ..: : :.
XP_016 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPL
410 420 430 440 450 460
210 220 230 240 250
pF1KE0 PG---PISGPISG---PNPGPIPG---PIPGPISG---PNPGPIPG---PISGPNPGL-I
:: : :. : : : :.:: : : :. : : : :.:: : : :: :
XP_016 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI
470 480 490 500 510 520
260 270 280 290 300
pF1KE0 PGPIPGPISG---PGPIIGP-IPSPAQIPGPGRLQGPGPILSPGR-MRSPGSLPGLAPIL
: : : : : : :. : :: : .:: : . : :. :: . : :::.. :
XP_016 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPL--PGVGIPPPPPLPGVG-IP
530 540 550 560 570
310 320 330 340 350 360
pF1KE0 GPGSGPGSG-SVPAPIPGPGSLPAPAPLWPQSPDASDFLPDTQLFPHFTELLLPLDPLEG
: ::.: : :.:: : ::::: : : .. .: :.: :: : :
XP_016 PPPPLPGAGIPPPPPLPGMGIPPAPAP--PLPPPGTG-IPPPPLLPVSGP---PLLPQVG
580 590 600 610 620 630
370 380 390 400 410
pF1KE0 SSVSTMTSQYQEGDDSMGKKHSGSQPQEEGGSVNENHSGPRLLLDL
::
XP_016 SSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSS
640 650 660 670 680 690
>>XP_016857329 (OMIM: 606373,616193) PREDICTED: formin-2 (1102 aa)
initn: 497 init1: 307 opt: 555 Z-score: 218.2 bits: 50.7 E(85289): 2e-05
Smith-Waterman score: 644; 37.0% identity (48.7% similar) in 392 aa overlap (30-367:260-632)
10 20 30 40 50
pF1KE0 MLSLREQQLQVWFKNRRAKLARERRLQQQPQRVPGQRGRGARAAPLVPAASASAPQRGP
: .::. ..: .: :.. :: :
XP_016 KNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGM------TVPTLP--STAIPQPPP
230 240 250 260 270 280
60 70 80 90 100 110
pF1KE0 ---SGILPAAEPTICSLH----QAWGGPGCRAQKGIPAALSPGPGPIP-APIPGPAQIPG
. .:: : . . : : .:.: : : :.: : :: : .::
XP_016 LQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG
290 300 310 320 330 340
120 130 140 150
pF1KE0 ---PLPGSIPGP-IPGPAQIPS---PIPAPIPGP-ISGPVQIPG---PFRGPIPGP-ISG
::: .:: :: : .:. : : :.:: : : .:: : :.:: :
XP_016 AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP
350 360 370 380 390 400
160 170 180 190 200
pF1KE0 PAPIPG---PISGPFSG---PNPGPIPG---PNPGPIPG---PISGPIPGPISVPIPGPI
: :.:: : :. : : : :.:: : : :.:: : :.:: ..: : :.
XP_016 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPL
410 420 430 440 450 460
210 220 230 240 250
pF1KE0 PG---PISGPISG---PNPGPIPG---PIPGPISG---PNPGPIPG---PISGPNPGL-I
:: : :. : : : :.:: : : :. : : : :.:: : : :: :
XP_016 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI
470 480 490 500 510 520
260 270 280 290 300
pF1KE0 PGPIPGPISG---PGPIIGP-IPSPAQIPGPGRLQGPGPILSPGR-MRSPGSLPGLAPIL
: : : : : : :. : :: : .:: : . : :. :: . : :::.. :
XP_016 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPL--PGVGIPPPPPLPGVG-IP
530 540 550 560 570
310 320 330 340 350 360
pF1KE0 GPGSGPGSG-SVPAPIPGPGSLPAPAPLWPQSPDASDFLPDTQLFPHFTELLLPLDPLEG
: ::.: : :.:: : ::::: : : .. .: :.: :: : :
XP_016 PPPPLPGAGIPPPPPLPGMGIPPAPAP--PLPPPGTG-IPPPPLLPVSGP---PLLPQVG
580 590 600 610 620 630
370 380 390 400 410
pF1KE0 SSVSTMTSQYQEGDDSMGKKHSGSQPQEEGGSVNENHSGPRLLLDL
::
XP_016 SSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSS
640 650 660 670 680 690
>>XP_016857328 (OMIM: 606373,616193) PREDICTED: formin-2 (1159 aa)
initn: 497 init1: 307 opt: 555 Z-score: 218.0 bits: 50.8 E(85289): 2.1e-05
Smith-Waterman score: 644; 37.0% identity (48.7% similar) in 392 aa overlap (30-367:317-689)
10 20 30 40 50
pF1KE0 MLSLREQQLQVWFKNRRAKLARERRLQQQPQRVPGQRGRGARAAPLVPAASASAPQRGP
: .::. ..: .: :.. :: :
XP_016 KNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGM------TVPTLP--STAIPQPPP
290 300 310 320 330
60 70 80 90 100 110
pF1KE0 ---SGILPAAEPTICSLH----QAWGGPGCRAQKGIPAALSPGPGPIP-APIPGPAQIPG
. .:: : . . : : .:.: : : :.: : :: : .::
XP_016 LQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG
340 350 360 370 380 390
120 130 140 150
pF1KE0 ---PLPGSIPGP-IPGPAQIPS---PIPAPIPGP-ISGPVQIPG---PFRGPIPGP-ISG
::: .:: :: : .:. : : :.:: : : .:: : :.:: :
XP_016 AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP
400 410 420 430 440 450
160 170 180 190 200
pF1KE0 PAPIPG---PISGPFSG---PNPGPIPG---PNPGPIPG---PISGPIPGPISVPIPGPI
: :.:: : :. : : : :.:: : : :.:: : :.:: ..: : :.
XP_016 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPL
460 470 480 490 500 510
210 220 230 240 250
pF1KE0 PG---PISGPISG---PNPGPIPG---PIPGPISG---PNPGPIPG---PISGPNPGL-I
:: : :. : : : :.:: : : :. : : : :.:: : : :: :
XP_016 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI
520 530 540 550 560 570
260 270 280 290 300
pF1KE0 PGPIPGPISG---PGPIIGP-IPSPAQIPGPGRLQGPGPILSPGR-MRSPGSLPGLAPIL
: : : : : : :. : :: : .:: : . : :. :: . : :::.. :
XP_016 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPL--PGVGIPPPPPLPGVG-IP
580 590 600 610 620 630
310 320 330 340 350 360
pF1KE0 GPGSGPGSG-SVPAPIPGPGSLPAPAPLWPQSPDASDFLPDTQLFPHFTELLLPLDPLEG
: ::.: : :.:: : ::::: : : .. .: :.: :: : :
XP_016 PPPPLPGAGIPPPPPLPGMGIPPAPAP--PLPPPGTG-IPPPPLLPVSGP---PLLPQVG
640 650 660 670 680
370 380 390 400 410
pF1KE0 SSVSTMTSQYQEGDDSMGKKHSGSQPQEEGGSVNENHSGPRLLLDL
::
XP_016 SSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSS
690 700 710 720 730 740
>>XP_011542539 (OMIM: 606373,616193) PREDICTED: formin-2 (1360 aa)
initn: 307 init1: 307 opt: 555 Z-score: 217.2 bits: 50.9 E(85289): 2.3e-05
Smith-Waterman score: 644; 37.0% identity (48.7% similar) in 392 aa overlap (30-367:884-1256)
10 20 30 40 50
pF1KE0 MLSLREQQLQVWFKNRRAKLARERRLQQQPQRVPGQRGRGARAAPLVPAASASAPQRGP
: .::. ..: .: :.. :: :
XP_011 KNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGM------TVPTLP--STAIPQPPP
860 870 880 890 900
60 70 80 90 100 110
pF1KE0 ---SGILPAAEPTICSLH----QAWGGPGCRAQKGIPAALSPGPGPIP-APIPGPAQIPG
. .:: : . . : : .:.: : : :.: : :: : .::
XP_011 LQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG
910 920 930 940 950 960
120 130 140 150
pF1KE0 ---PLPGSIPGP-IPGPAQIPS---PIPAPIPGP-ISGPVQIPG---PFRGPIPGP-ISG
::: .:: :: : .:. : : :.:: : : .:: : :.:: :
XP_011 AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP
970 980 990 1000 1010 1020
160 170 180 190 200
pF1KE0 PAPIPG---PISGPFSG---PNPGPIPG---PNPGPIPG---PISGPIPGPISVPIPGPI
: :.:: : :. : : : :.:: : : :.:: : :.:: ..: : :.
XP_011 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPL
1030 1040 1050 1060 1070 1080
210 220 230 240 250
pF1KE0 PG---PISGPISG---PNPGPIPG---PIPGPISG---PNPGPIPG---PISGPNPGL-I
:: : :. : : : :.:: : : :. : : : :.:: : : :: :
XP_011 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI
1090 1100 1110 1120 1130 1140
260 270 280 290 300
pF1KE0 PGPIPGPISG---PGPIIGP-IPSPAQIPGPGRLQGPGPILSPGR-MRSPGSLPGLAPIL
: : : : : : :. : :: : .:: : . : :. :: . : :::.. :
XP_011 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPL--PGVGIPPPPPLPGVG-IP
1150 1160 1170 1180 1190 1200
310 320 330 340 350 360
pF1KE0 GPGSGPGSG-SVPAPIPGPGSLPAPAPLWPQSPDASDFLPDTQLFPHFTELLLPLDPLEG
: ::.: : :.:: : ::::: : : .. .: :.: :: : :
XP_011 PPPPLPGAGIPPPPPLPGMGIPPAPAP--PLPPPGTG-IPPPPLLPVSGP---PLLPQVG
1210 1220 1230 1240 1250
370 380 390 400 410
pF1KE0 SSVSTMTSQYQEGDDSMGKKHSGSQPQEEGGSVNENHSGPRLLLDL
::
XP_011 SSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSS
1260 1270 1280 1290 1300 1310
>>XP_016857327 (OMIM: 606373,616193) PREDICTED: formin-2 (1384 aa)
initn: 307 init1: 307 opt: 555 Z-score: 217.1 bits: 50.9 E(85289): 2.4e-05
Smith-Waterman score: 644; 37.0% identity (48.7% similar) in 392 aa overlap (30-367:884-1256)
10 20 30 40 50
pF1KE0 MLSLREQQLQVWFKNRRAKLARERRLQQQPQRVPGQRGRGARAAPLVPAASASAPQRGP
: .::. ..: .: :.. :: :
XP_016 KNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGM------TVPTLP--STAIPQPPP
860 870 880 890 900
60 70 80 90 100 110
pF1KE0 ---SGILPAAEPTICSLH----QAWGGPGCRAQKGIPAALSPGPGPIP-APIPGPAQIPG
. .:: : . . : : .:.: : : :.: : :: : .::
XP_016 LQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG
910 920 930 940 950 960
120 130 140 150
pF1KE0 ---PLPGSIPGP-IPGPAQIPS---PIPAPIPGP-ISGPVQIPG---PFRGPIPGP-ISG
::: .:: :: : .:. : : :.:: : : .:: : :.:: :
XP_016 AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP
970 980 990 1000 1010 1020
160 170 180 190 200
pF1KE0 PAPIPG---PISGPFSG---PNPGPIPG---PNPGPIPG---PISGPIPGPISVPIPGPI
: :.:: : :. : : : :.:: : : :.:: : :.:: ..: : :.
XP_016 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPL
1030 1040 1050 1060 1070 1080
210 220 230 240 250
pF1KE0 PG---PISGPISG---PNPGPIPG---PIPGPISG---PNPGPIPG---PISGPNPGL-I
:: : :. : : : :.:: : : :. : : : :.:: : : :: :
XP_016 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI
1090 1100 1110 1120 1130 1140
260 270 280 290 300
pF1KE0 PGPIPGPISG---PGPIIGP-IPSPAQIPGPGRLQGPGPILSPGR-MRSPGSLPGLAPIL
: : : : : : :. : :: : .:: : . : :. :: . : :::.. :
XP_016 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPL--PGVGIPPPPPLPGVG-IP
1150 1160 1170 1180 1190 1200
310 320 330 340 350 360
pF1KE0 GPGSGPGSG-SVPAPIPGPGSLPAPAPLWPQSPDASDFLPDTQLFPHFTELLLPLDPLEG
: ::.: : :.:: : ::::: : : .. .: :.: :: : :
XP_016 PPPPLPGAGIPPPPPLPGMGIPPAPAP--PLPPPGTG-IPPPPLLPVSGP---PLLPQVG
1210 1220 1230 1240 1250
370 380 390 400 410
pF1KE0 SSVSTMTSQYQEGDDSMGKKHSGSQPQEEGGSVNENHSGPRLLLDL
::
XP_016 SSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSS
1260 1270 1280 1290 1300 1310
>>XP_016857326 (OMIM: 606373,616193) PREDICTED: formin-2 (1417 aa)
initn: 307 init1: 307 opt: 555 Z-score: 217.0 bits: 50.9 E(85289): 2.4e-05
Smith-Waterman score: 644; 37.0% identity (48.7% similar) in 392 aa overlap (30-367:884-1256)
10 20 30 40 50
pF1KE0 MLSLREQQLQVWFKNRRAKLARERRLQQQPQRVPGQRGRGARAAPLVPAASASAPQRGP
: .::. ..: .: :.. :: :
XP_016 KNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGM------TVPTLP--STAIPQPPP
860 870 880 890 900
60 70 80 90 100 110
pF1KE0 ---SGILPAAEPTICSLH----QAWGGPGCRAQKGIPAALSPGPGPIP-APIPGPAQIPG
. .:: : . . : : .:.: : : :.: : :: : .::
XP_016 LQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG
910 920 930 940 950 960
120 130 140 150
pF1KE0 ---PLPGSIPGP-IPGPAQIPS---PIPAPIPGP-ISGPVQIPG---PFRGPIPGP-ISG
::: .:: :: : .:. : : :.:: : : .:: : :.:: :
XP_016 AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP
970 980 990 1000 1010 1020
160 170 180 190 200
pF1KE0 PAPIPG---PISGPFSG---PNPGPIPG---PNPGPIPG---PISGPIPGPISVPIPGPI
: :.:: : :. : : : :.:: : : :.:: : :.:: ..: : :.
XP_016 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPL
1030 1040 1050 1060 1070 1080
210 220 230 240 250
pF1KE0 PG---PISGPISG---PNPGPIPG---PIPGPISG---PNPGPIPG---PISGPNPGL-I
:: : :. : : : :.:: : : :. : : : :.:: : : :: :
XP_016 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI
1090 1100 1110 1120 1130 1140
260 270 280 290 300
pF1KE0 PGPIPGPISG---PGPIIGP-IPSPAQIPGPGRLQGPGPILSPGR-MRSPGSLPGLAPIL
: : : : : : :. : :: : .:: : . : :. :: . : :::.. :
XP_016 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPL--PGVGIPPPPPLPGVG-IP
1150 1160 1170 1180 1190 1200
310 320 330 340 350 360
pF1KE0 GPGSGPGSG-SVPAPIPGPGSLPAPAPLWPQSPDASDFLPDTQLFPHFTELLLPLDPLEG
: ::.: : :.:: : ::::: : : .. .: :.: :: : :
XP_016 PPPPLPGAGIPPPPPLPGMGIPPAPAP--PLPPPGTG-IPPPPLLPVSGP---PLLPQVG
1210 1220 1230 1240 1250
370 380 390 400 410
pF1KE0 SSVSTMTSQYQEGDDSMGKKHSGSQPQEEGGSVNENHSGPRLLLDL
::
XP_016 SSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSS
1260 1270 1280 1290 1300 1310
>>NP_064450 (OMIM: 606373,616193) formin-2 isoform 2 [Ho (1722 aa)
initn: 307 init1: 307 opt: 555 Z-score: 216.1 bits: 51.0 E(85289): 2.7e-05
Smith-Waterman score: 644; 37.0% identity (48.7% similar) in 392 aa overlap (30-367:880-1252)
10 20 30 40 50
pF1KE0 MLSLREQQLQVWFKNRRAKLARERRLQQQPQRVPGQRGRGARAAPLVPAASASAPQRGP
: .::. ..: .: :.. :: :
NP_064 KNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGM------TVPTLP--STAIPQPPP
850 860 870 880 890 900
60 70 80 90 100 110
pF1KE0 ---SGILPAAEPTICSLH----QAWGGPGCRAQKGIPAALSPGPGPIP-APIPGPAQIPG
. .:: : . . : : .:.: : : :.: : :: : .::
NP_064 LQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG
910 920 930 940 950 960
120 130 140 150
pF1KE0 ---PLPGSIPGP-IPGPAQIPS---PIPAPIPGP-ISGPVQIPG---PFRGPIPGP-ISG
::: .:: :: : .:. : : :.:: : : .:: : :.:: :
NP_064 AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP
970 980 990 1000 1010 1020
160 170 180 190 200
pF1KE0 PAPIPG---PISGPFSG---PNPGPIPG---PNPGPIPG---PISGPIPGPISVPIPGPI
: :.:: : :. : : : :.:: : : :.:: : :.:: ..: : :.
NP_064 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPL
1030 1040 1050 1060 1070 1080
210 220 230 240 250
pF1KE0 PG---PISGPISG---PNPGPIPG---PIPGPISG---PNPGPIPG---PISGPNPGL-I
:: : :. : : : :.:: : : :. : : : :.:: : : :: :
NP_064 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI
1090 1100 1110 1120 1130 1140
260 270 280 290 300
pF1KE0 PGPIPGPISG---PGPIIGP-IPSPAQIPGPGRLQGPGPILSPGR-MRSPGSLPGLAPIL
: : : : : : :. : :: : .:: : . : :. :: . : :::.. :
NP_064 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPL--PGVGIPPPPPLPGVG-IP
1150 1160 1170 1180 1190
310 320 330 340 350 360
pF1KE0 GPGSGPGSG-SVPAPIPGPGSLPAPAPLWPQSPDASDFLPDTQLFPHFTELLLPLDPLEG
: ::.: : :.:: : ::::: : : .. .: :.: :: : :
NP_064 PPPPLPGAGIPPPPPLPGMGIPPAPAP--PLPPPGTG-IPPPPLLPVSGP---PLLPQVG
1200 1210 1220 1230 1240 1250
370 380 390 400 410
pF1KE0 SSVSTMTSQYQEGDDSMGKKHSGSQPQEEGGSVNENHSGPRLLLDL
::
NP_064 SSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSS
1260 1270 1280 1290 1300 1310
>>NP_001292353 (OMIM: 606373,616193) formin-2 isoform 1 (1726 aa)
initn: 307 init1: 307 opt: 555 Z-score: 216.1 bits: 51.0 E(85289): 2.7e-05
Smith-Waterman score: 644; 37.0% identity (48.7% similar) in 392 aa overlap (30-367:884-1256)
10 20 30 40 50
pF1KE0 MLSLREQQLQVWFKNRRAKLARERRLQQQPQRVPGQRGRGARAAPLVPAASASAPQRGP
: .::. ..: .: :.. :: :
NP_001 KNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGM------TVPTLP--STAIPQPPP
860 870 880 890 900
60 70 80 90 100 110
pF1KE0 ---SGILPAAEPTICSLH----QAWGGPGCRAQKGIPAALSPGPGPIP-APIPGPAQIPG
. .:: : . . : : .:.: : : :.: : :: : .::
NP_001 LQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG
910 920 930 940 950 960
120 130 140 150
pF1KE0 ---PLPGSIPGP-IPGPAQIPS---PIPAPIPGP-ISGPVQIPG---PFRGPIPGP-ISG
::: .:: :: : .:. : : :.:: : : .:: : :.:: :
NP_001 AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP
970 980 990 1000 1010 1020
160 170 180 190 200
pF1KE0 PAPIPG---PISGPFSG---PNPGPIPG---PNPGPIPG---PISGPIPGPISVPIPGPI
: :.:: : :. : : : :.:: : : :.:: : :.:: ..: : :.
NP_001 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPL
1030 1040 1050 1060 1070 1080
210 220 230 240 250
pF1KE0 PG---PISGPISG---PNPGPIPG---PIPGPISG---PNPGPIPG---PISGPNPGL-I
:: : :. : : : :.:: : : :. : : : :.:: : : :: :
NP_001 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI
1090 1100 1110 1120 1130 1140
260 270 280 290 300
pF1KE0 PGPIPGPISG---PGPIIGP-IPSPAQIPGPGRLQGPGPILSPGR-MRSPGSLPGLAPIL
: : : : : : :. : :: : .:: : . : :. :: . : :::.. :
NP_001 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPL--PGVGIPPPPPLPGVG-IP
1150 1160 1170 1180 1190 1200
310 320 330 340 350 360
pF1KE0 GPGSGPGSG-SVPAPIPGPGSLPAPAPLWPQSPDASDFLPDTQLFPHFTELLLPLDPLEG
: ::.: : :.:: : ::::: : : .. .: :.: :: : :
NP_001 PPPPLPGAGIPPPPPLPGMGIPPAPAP--PLPPPGTG-IPPPPLLPVSGP---PLLPQVG
1210 1220 1230 1240 1250
370 380 390 400 410
pF1KE0 SSVSTMTSQYQEGDDSMGKKHSGSQPQEEGGSVNENHSGPRLLLDL
::
NP_001 SSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSS
1260 1270 1280 1290 1300 1310
>>XP_016884752 (OMIM: 301050,303630) PREDICTED: collagen (1136 aa)
initn: 254 init1: 144 opt: 478 Z-score: 191.7 bits: 45.9 E(85289): 0.00061
Smith-Waterman score: 538; 35.7% identity (51.2% similar) in 434 aa overlap (35-406:3-408)
10 20 30 40 50 60
pF1KE0 REQQLQVWFKNRRAKLARERRLQQQPQRVPGQRGR-GARAAPLVPAASASAPQRGPSGIL
:..:. :. .:: .:. .. : : :.
XP_016 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLP
10 20 30
70 80 90 100 110
pF1KE0 -PAAEPTICSLHQAWGGPGCRAQKGIPAALSP-GP---GPIPAP-----IPGPAQIPGPL
: .:: ... : :: . :.:. ..: :: :: :.: : : : ::
XP_016 GPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP-PGPVGEKGIQGVAGNPGQ-
40 50 60 70 80 90
120 130 140 150 160
pF1KE0 PGSIPGPIPGPAQ-IPSPIPAPIPG-PI-SGPVQIPG----PFRGPIPG-PISGPAP-IP
:: :::: :.: : .: .:: : .: : .:: : . .:: : : : ::
XP_016 PG-IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIP
100 110 120 130 140
170 180 190 200 210
pF1KE0 G-PISGPFSGPNPGP-IPGPNPGP-IPGPIS--GP-----IPGPISVP---IPGPIPGPI
: . :: ::. : :::: .: :: :. :: .::: . : .::: :::
XP_016 GIGLPGP-PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGP-PGPP
150 160 170 180 190 200
220 230 240 250
pF1KE0 SGP----ISGPN-----PGPIPGP--------IPGPISGPNPGPIPGPISGPN-PGL-IP
. : ::. ::: ::: .::: . .:. :::.. :. ::. .
XP_016 GLPGFKGALGPKGDRGFPGP-PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQ
210 220 230 240 250 260
260 270 280 290 300
pF1KE0 GPIPGPISGPGPIIGP----IPSPAQIPGPGRLQGPGPILSPGRMRSPGSLPGLAPILGP
:: ::: . :::: : ::. ::: :. ::: ::. ::: .:: :: ::
XP_016 GP-PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGP---PGERGSPG-IPG-AP--GP
270 280 290 300 310
310 320 330 340 350 360
pF1KE0 GSGPGSGSVP--APIPG-PGSLPAPAPLWPQSPDASDFLPDTQLFPHFTELLLPLDPLEG
. ::: ..: : : ::. . . : .: . .: . : : : :.:
XP_016 IGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG----LKGDDGLQG
320 330 340 350 360 370
370 380 390 400 410
pF1KE0 SSVSTMTSQYQEG-DDSMGKKHSGSQPQEEG--GSVNENHSGPRLLLDL
: : :.: : ..: : : .. : : .
XP_016 ----------QPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSG
380 390 400 410 420
XP_016 PKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQG
430 440 450 460 470 480
411 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:39:44 2016 done: Tue Nov 8 04:39:45 2016
Total Scan time: 7.370 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]