Result of FASTA (omim) for
pFN21AE0628
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0628, 372 aa
1>>>pF1KE0628 372 - 372 aa - 372 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.5246+/-0.000762; mu= -14.8579+/- 0.044
mean_var=735.9786+/-168.764, 0's: 0 Z-trim(113.4): 1620 B-trim: 378 in 1/50
Lambda= 0.047276
statistics sampled from 20729 (22789) to 20729 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.626), E-opt: 0.2 (0.267), width: 16
Scan time: 7.530
The best scores are: opt bits E(85289)
XP_011510470 (OMIM: 604727) PREDICTED: serine/thre ( 372) 2459 183.9 5.2e-46
XP_011510471 (OMIM: 604727) PREDICTED: serine/thre ( 372) 2459 183.9 5.2e-46
NP_004217 (OMIM: 604727) serine/threonine-protein ( 372) 2459 183.9 5.2e-46
XP_011510472 (OMIM: 604727) PREDICTED: serine/thre ( 372) 2459 183.9 5.2e-46
XP_011510473 (OMIM: 604727) PREDICTED: serine/thre ( 244) 1627 126.9 5e-29
NP_004751 (OMIM: 604726) serine/threonine-protein ( 414) 1230 100.1 9.4e-21
XP_016868281 (OMIM: 604726) PREDICTED: serine/thre ( 323) 1063 88.6 2.2e-17
XP_005259565 (OMIM: 603289) PREDICTED: death-assoc ( 454) 860 75.0 3.9e-13
NP_001339 (OMIM: 603289) death-associated protein ( 454) 860 75.0 3.9e-13
XP_005251814 (OMIM: 600831) PREDICTED: death-assoc ( 839) 865 75.7 4.3e-13
NP_001275660 (OMIM: 600831) death-associated prote (1430) 865 76.1 5.8e-13
NP_001275658 (OMIM: 600831) death-associated prote (1430) 865 76.1 5.8e-13
NP_004929 (OMIM: 600831) death-associated protein (1430) 865 76.1 5.8e-13
NP_001275659 (OMIM: 600831) death-associated prote (1430) 865 76.1 5.8e-13
XP_016877533 (OMIM: 616567) PREDICTED: death-assoc ( 350) 832 72.9 1.3e-12
NP_055141 (OMIM: 616567) death-associated protein ( 370) 832 72.9 1.3e-12
XP_011519716 (OMIM: 616567) PREDICTED: death-assoc ( 380) 832 72.9 1.3e-12
XP_011519715 (OMIM: 616567) PREDICTED: death-assoc ( 389) 832 73.0 1.4e-12
XP_011519718 (OMIM: 616567) PREDICTED: death-assoc ( 488) 833 73.2 1.5e-12
XP_011519717 (OMIM: 616567) PREDICTED: death-assoc ( 359) 829 72.7 1.5e-12
XP_016877534 (OMIM: 616567) PREDICTED: death-assoc ( 316) 802 70.8 5e-12
XP_016877535 (OMIM: 616567) PREDICTED: death-assoc ( 316) 802 70.8 5e-12
XP_011519719 (OMIM: 616567) PREDICTED: death-assoc ( 316) 802 70.8 5e-12
NP_149109 (OMIM: 192600,606566) myosin light chain ( 596) 682 63.0 2e-09
XP_016861959 (OMIM: 600922,613780) PREDICTED: myos ( 713) 667 62.1 4.6e-09
XP_016861960 (OMIM: 600922,613780) PREDICTED: myos ( 714) 667 62.1 4.6e-09
XP_016861958 (OMIM: 600922,613780) PREDICTED: myos ( 991) 667 62.3 5.5e-09
NP_001295230 (OMIM: 612147) myosin light chain kin ( 478) 654 60.9 6.8e-09
XP_006721397 (OMIM: 612147) PREDICTED: myosin ligh ( 478) 654 60.9 6.8e-09
NP_001308238 (OMIM: 600922,613780) myosin light ch (1738) 667 62.7 7.5e-09
NP_444254 (OMIM: 600922,613780) myosin light chain (1845) 667 62.7 7.7e-09
XP_011511162 (OMIM: 600922,613780) PREDICTED: myos (1913) 667 62.7 7.9e-09
NP_444253 (OMIM: 600922,613780) myosin light chain (1914) 667 62.7 7.9e-09
NP_872299 (OMIM: 612147) myosin light chain kinase ( 819) 654 61.3 9.2e-09
NP_001309922 (OMIM: 604605,608901) kalirin isoform (1288) 637 60.4 2.6e-08
NP_008995 (OMIM: 604605,608901) kalirin isoform 3 (1289) 637 60.4 2.6e-08
XP_016862919 (OMIM: 604605,608901) PREDICTED: kali (2955) 637 61.0 4.1e-08
XP_006713877 (OMIM: 604605,608901) PREDICTED: kali (2956) 637 61.0 4.1e-08
XP_006713876 (OMIM: 604605,608901) PREDICTED: kali (2966) 637 61.0 4.1e-08
XP_016862918 (OMIM: 604605,608901) PREDICTED: kali (2968) 637 61.0 4.1e-08
XP_006713875 (OMIM: 604605,608901) PREDICTED: kali (2975) 637 61.0 4.1e-08
XP_011511583 (OMIM: 604605,608901) PREDICTED: kali (2977) 637 61.0 4.1e-08
XP_006713874 (OMIM: 604605,608901) PREDICTED: kali (2979) 637 61.0 4.1e-08
NP_001019831 (OMIM: 604605,608901) kalirin isoform (2986) 637 61.0 4.1e-08
XP_011511581 (OMIM: 604605,608901) PREDICTED: kali (2987) 637 61.0 4.1e-08
XP_011511582 (OMIM: 604605,608901) PREDICTED: kali (2987) 637 61.0 4.1e-08
XP_006713873 (OMIM: 604605,608901) PREDICTED: kali (2988) 637 61.0 4.1e-08
XP_016865292 (OMIM: 601893,617061) PREDICTED: trip (2612) 613 59.3 1.2e-07
XP_011512412 (OMIM: 601893,617061) PREDICTED: trip (3038) 613 59.4 1.3e-07
XP_011512411 (OMIM: 601893,617061) PREDICTED: trip (3048) 613 59.4 1.3e-07
>>XP_011510470 (OMIM: 604727) PREDICTED: serine/threonin (372 aa)
initn: 2459 init1: 2459 opt: 2459 Z-score: 947.0 bits: 183.9 E(85289): 5.2e-46
Smith-Waterman score: 2459; 100.0% identity (100.0% similar) in 372 aa overlap (1-372:1-372)
10 20 30 40 50 60
pF1KE0 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 QETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSL
310 320 330 340 350 360
370
pF1KE0 PNPHELVSDLLC
::::::::::::
XP_011 PNPHELVSDLLC
370
>>XP_011510471 (OMIM: 604727) PREDICTED: serine/threonin (372 aa)
initn: 2459 init1: 2459 opt: 2459 Z-score: 947.0 bits: 183.9 E(85289): 5.2e-46
Smith-Waterman score: 2459; 100.0% identity (100.0% similar) in 372 aa overlap (1-372:1-372)
10 20 30 40 50 60
pF1KE0 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 QETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSL
310 320 330 340 350 360
370
pF1KE0 PNPHELVSDLLC
::::::::::::
XP_011 PNPHELVSDLLC
370
>>NP_004217 (OMIM: 604727) serine/threonine-protein kina (372 aa)
initn: 2459 init1: 2459 opt: 2459 Z-score: 947.0 bits: 183.9 E(85289): 5.2e-46
Smith-Waterman score: 2459; 100.0% identity (100.0% similar) in 372 aa overlap (1-372:1-372)
10 20 30 40 50 60
pF1KE0 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 QETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSL
310 320 330 340 350 360
370
pF1KE0 PNPHELVSDLLC
::::::::::::
NP_004 PNPHELVSDLLC
370
>>XP_011510472 (OMIM: 604727) PREDICTED: serine/threonin (372 aa)
initn: 2459 init1: 2459 opt: 2459 Z-score: 947.0 bits: 183.9 E(85289): 5.2e-46
Smith-Waterman score: 2459; 100.0% identity (100.0% similar) in 372 aa overlap (1-372:1-372)
10 20 30 40 50 60
pF1KE0 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 QETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSL
310 320 330 340 350 360
370
pF1KE0 PNPHELVSDLLC
::::::::::::
XP_011 PNPHELVSDLLC
370
>>XP_011510473 (OMIM: 604727) PREDICTED: serine/threonin (244 aa)
initn: 1627 init1: 1627 opt: 1627 Z-score: 642.1 bits: 126.9 E(85289): 5e-29
Smith-Waterman score: 1627; 100.0% identity (100.0% similar) in 244 aa overlap (129-372:1-244)
100 110 120 130 140 150
pF1KE0 VYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLD
::::::::::::::::::::::::::::::
XP_011 MVSENDVIRLIKQILEGVYYLHQNNIVHLD
10 20 30
160 170 180 190 200 210
pF1KE0 LKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDM
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE0 WNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNP
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE0 EKRPTAEICLSHSWLQQWDFENLFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRPTAEICLSHSWLQQWDFENLFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDRE
160 170 180 190 200 210
340 350 360 370
pF1KE0 DKENIPEDSSMVSKRFRFDDSLPNPHELVSDLLC
::::::::::::::::::::::::::::::::::
XP_011 DKENIPEDSSMVSKRFRFDDSLPNPHELVSDLLC
220 230 240
>>NP_004751 (OMIM: 604726) serine/threonine-protein kina (414 aa)
initn: 1259 init1: 1202 opt: 1230 Z-score: 493.6 bits: 100.1 E(85289): 9.4e-21
Smith-Waterman score: 1251; 54.5% identity (78.9% similar) in 374 aa overlap (13-367:41-413)
10 20 30 40
pF1KE0 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILT-SKELGR
:::: . .. : :.. : : ..::::
NP_004 GSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAV-VRTEPFQDGYSLCPGRELGR
20 30 40 50 60
50 60 70 80 90 100
pF1KE0 GKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYE
:::::::.::.:..:.:.::::..:::.::::: ::.:::::::::.. : :::::::::
NP_004 GKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVINLHEVYE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 NTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKP
..::.::.::::::::::. :. . : .:.:: ::..::::::..:: ..:::::::
NP_004 TASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKP
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 QNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNI
:::::.: :::::::::::.:: . .. :::::::::::.:::::.::::. :::::.:
NP_004 QNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSI
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 GIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKR
:...:..:: :::.:.:.:::.:::::.:..:::: :. .:. :.:::..::::.:: :
NP_004 GVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDR
250 260 270 280 290 300
290 300 310 320
pF1KE0 PTAEICLSHSWLQQWDF-ENLFHPEET--SSSSQTQDHSV---RSSEDKT-SKSS-----
::: ::.: :: : .. : :. :.. ... . ::: :. ::. .: :
NP_004 ATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSETKESIVTEE
310 320 330 340 350 360
330 340 350 360 370
pF1KE0 ----CNGTCGDREDKENIPEDSSMVSKRFRFDDSLPN--PHELVSDLLC
. : :. ...:. ... .::::.:.. : . : :..
NP_004 LIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY
370 380 390 400 410
>>XP_016868281 (OMIM: 604726) PREDICTED: serine/threonin (323 aa)
initn: 1103 init1: 1046 opt: 1063 Z-score: 433.1 bits: 88.6 E(85289): 2.2e-17
Smith-Waterman score: 1084; 54.7% identity (78.9% similar) in 322 aa overlap (64-367:1-322)
40 50 60 70 80 90
pF1KE0 LTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRV
..:::.::::: ::.:::::::::.. : :
XP_016 MRKRRKGQDCRMEIIHEIAVLELAQDNPWV
10 20 30
100 110 120 130 140 150
pF1KE0 INLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNN
::::::::..::.::.::::::::::. :. . : .:.:: ::..::::::..:: .
XP_016 INLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRD
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE0 IVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPIT
.::::::::::::.: :::::::::::.:: . .. :::::::::::.:::::.::::.
XP_016 VVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPIS
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE0 TATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSL
:::::.::...:..:: :::.:.:.:::.:::::.:..:::: :. .:. :.:::..:
XP_016 MATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTL
160 170 180 190 200 210
280 290 300 310 320
pF1KE0 LVKNPEKRPTAEICLSHSWLQQWDF-ENLFHPEET--SSSSQTQDHSV---RSSEDKT-S
:::.:: : ::: ::.: :: : .. : :. :.. ... . ::: :. ::. .
XP_016 LVKKPEDRATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSET
220 230 240 250 260 270
330 340 350 360 370
pF1KE0 KSS---------CNGTCGDREDKENIPEDSSMVSKRFRFDDSLPN--PHELVSDLLC
: : . : :. ...:. ... .::::.:.. : . : :..
XP_016 KESIVTEELIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY
280 290 300 310 320
>>XP_005259565 (OMIM: 603289) PREDICTED: death-associate (454 aa)
initn: 829 init1: 461 opt: 860 Z-score: 356.8 bits: 75.0 E(85289): 3.9e-13
Smith-Waterman score: 860; 41.6% identity (73.9% similar) in 341 aa overlap (24-355:5-340)
10 20 30 40 50 60
pF1KE0 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
..:. .. : . ..::: :.::.::.: .:.::.:::
XP_005 MSTFRQEDVEDHYEM-GEELGSGQFAIVRKCRQKGTGKEYA
10 20 30 40
70 80 90 100 110
pF1KE0 AKFLKKRR-----RGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAG
:::.:::: :: . : :: .:. .:. . : .:.::...:: ....:::: ..:
XP_005 AKFIKKRRLSSSRRGVS-REEIEREVNILREIRH-PNIITLHDIFENKTDVVLILELVSG
50 60 70 80 90
120 130 140 150 160 170
pF1KE0 GEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNI-LLSSIYPLGD
::.:.. : : : ..:... ...::::.::.:::.. :.:.::::.:: ::.. :
XP_005 GELFDF-LAE-KESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPR
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 IKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSP
::..:::...:: . :...:.::::..::::.::.:. .:::.::.:.:.::. .::
XP_005 IKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASP
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 FVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQ
:.:: .::: ::: :: :..:: ::..:.:: :::. ::::.:..: : : :::..
XP_005 FLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIK
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE0 QWDFENLFHPEETSSSSQTQDHSVRSSEDKTSKSSC---NGTCGDREDKENIPEDSSMVS
.:. . . . . ...: .: .. : :.. .: : .. :... .
XP_005 AIRRRNVRGEDSGRKPERRRLKTTRLKEYTIKSHSSLPPNNSYADFERFSKVLEEAAAAE
280 290 300 310 320 330
360 370
pF1KE0 KRFRFDDSLPNPHELVSDLLC
. .:
XP_005 EGLRELQRSRRLCHEDVEALAAIYEEKEAWYREESDSLGQDLRRLRQELLKTEALKRQAQ
340 350 360 370 380 390
>>NP_001339 (OMIM: 603289) death-associated protein kina (454 aa)
initn: 829 init1: 461 opt: 860 Z-score: 356.8 bits: 75.0 E(85289): 3.9e-13
Smith-Waterman score: 860; 41.6% identity (73.9% similar) in 341 aa overlap (24-355:5-340)
10 20 30 40 50 60
pF1KE0 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
..:. .. : . ..::: :.::.::.: .:.::.:::
NP_001 MSTFRQEDVEDHYEM-GEELGSGQFAIVRKCRQKGTGKEYA
10 20 30 40
70 80 90 100 110
pF1KE0 AKFLKKRR-----RGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAG
:::.:::: :: . : :: .:. .:. . : .:.::...:: ....:::: ..:
NP_001 AKFIKKRRLSSSRRGVS-REEIEREVNILREIRH-PNIITLHDIFENKTDVVLILELVSG
50 60 70 80 90
120 130 140 150 160 170
pF1KE0 GEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNI-LLSSIYPLGD
::.:.. : : : ..:... ...::::.::.:::.. :.:.::::.:: ::.. :
NP_001 GELFDF-LAE-KESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPR
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 IKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSP
::..:::...:: . :...:.::::..::::.::.:. .:::.::.:.:.::. .::
NP_001 IKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASP
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 FVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQ
:.:: .::: ::: :: :..:: ::..:.:: :::. ::::.:..: : : :::..
NP_001 FLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIK
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE0 QWDFENLFHPEETSSSSQTQDHSVRSSEDKTSKSSC---NGTCGDREDKENIPEDSSMVS
.:. . . . . ...: .: .. : :.. .: : .. :... .
NP_001 AIRRRNVRGEDSGRKPERRRLKTTRLKEYTIKSHSSLPPNNSYADFERFSKVLEEAAAAE
280 290 300 310 320 330
360 370
pF1KE0 KRFRFDDSLPNPHELVSDLLC
. .:
NP_001 EGLRELQRSRRLCHEDVEALAAIYEEKEAWYREESDSLGQDLRRLRQELLKTEALKRQAQ
340 350 360 370 380 390
>>XP_005251814 (OMIM: 600831) PREDICTED: death-associate (839 aa)
initn: 815 init1: 420 opt: 865 Z-score: 356.0 bits: 75.7 E(85289): 4.3e-13
Smith-Waterman score: 873; 42.5% identity (72.4% similar) in 369 aa overlap (24-370:5-367)
10 20 30 40 50 60
pF1KE0 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
..:: ...: :..::: :.::::..: :::: .::
XP_005 MTVFRQENVDDYYD-TGEELGSGQFAVVKKCREKSTGLQYA
10 20 30 40
70 80 90 100 110
pF1KE0 AKFLKKRR-----RGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAG
:::.:::: :: . : .: .:...:. . : ::.::::::: ...::::: .::
XP_005 AKFIKKRRTKSSRRGVS-REDIEREVSILKEIQH-PNVITLHEVYENKTDVILILELVAG
50 60 70 80 90
120 130 140 150 160 170
pF1KE0 GEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNI-LLSSIYPLGD
::.:.. : : : ..:... ...::::.::::::. .:.:.::::.:: ::. :
XP_005 GELFDF-LAE-KESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPR
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 IKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSP
:::.:::...:: . :...:.::::..::::.::.:. .:::.::.:.:.::. .::
XP_005 IKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASP
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 FVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQ
:.:. .::: :.: :: .. .: ::..: :: :::. ::::.:.:: : . :.: :..
XP_005 FLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK
220 230 240 250 260 270
300 310 320 330 340
pF1KE0 QWDFENLFHPEETS---------SSSQTQDHSVR--SSEDKTSKS--SCNGTCGDREDKE
: .. . . .. .. . .::: : .. :.: : .. : : .
XP_005 PKDTQQALSRKASAVNMEKFKKFAARKKWKQSVRLISLCQRLSRSFLSRSNMSVARSD-D
280 290 300 310 320 330
350 360 370
pF1KE0 NIPEDSSMVSKRFRF---DDSLPNPHELVSDLLC
.. :..:.: : . ::..:. ..:...:
XP_005 TLDEEDSFVMKAIIHAINDDNVPGLQHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQIL
340 350 360 370 380 390
XP_005 QLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARY
400 410 420 430 440 450
372 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:23:46 2016 done: Tue Nov 8 01:23:48 2016
Total Scan time: 7.530 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]