Result of FASTA (ccds) for
pFN21AE0462
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0462, 227 aa
1>>>pF1KE0462 227 - 227 aa - 227 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9301+/-0.000753; mu= 10.9354+/- 0.045
mean_var=70.9104+/-14.038, 0's: 0 Z-trim(109.0): 18 B-trim: 15 in 1/52
Lambda= 0.152307
statistics sampled from 10604 (10619) to 10604 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.326), width: 16
Scan time: 2.220
The best scores are: opt bits E(32554)
CCDS5493.1 TMED4 gene_id:222068|Hs108|chr7 ( 227) 1519 342.4 1.4e-94
CCDS78227.1 TMED4 gene_id:222068|Hs108|chr7 ( 186) 1197 271.6 2.4e-73
CCDS4428.1 TMED9 gene_id:54732|Hs108|chr5 ( 235) 1172 266.2 1.3e-71
CCDS78226.1 TMED4 gene_id:222068|Hs108|chr7 ( 178) 880 202.0 2.1e-52
CCDS9840.1 TMED10 gene_id:10972|Hs108|chr14 ( 219) 319 78.7 3.3e-15
CCDS9250.1 TMED2 gene_id:10959|Hs108|chr12 ( 201) 253 64.2 7e-11
>>CCDS5493.1 TMED4 gene_id:222068|Hs108|chr7 (227 aa)
initn: 1519 init1: 1519 opt: 1519 Z-score: 1811.4 bits: 342.4 E(32554): 1.4e-94
Smith-Waterman score: 1519; 100.0% identity (100.0% similar) in 227 aa overlap (1-227:1-227)
10 20 30 40 50 60
pF1KE0 MAGVGAGPLRAMGRQALLLLALCATGAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MAGVGAGPLRAMGRQALLLLALCATGAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 WDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYR
130 140 150 160 170 180
190 200 210 220
pF1KE0 EERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV
:::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV
190 200 210 220
>>CCDS78227.1 TMED4 gene_id:222068|Hs108|chr7 (186 aa)
initn: 1197 init1: 1197 opt: 1197 Z-score: 1430.4 bits: 271.6 E(32554): 2.4e-73
Smith-Waterman score: 1197; 100.0% identity (100.0% similar) in 178 aa overlap (1-178:1-178)
10 20 30 40 50 60
pF1KE0 MAGVGAGPLRAMGRQALLLLALCATGAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 MAGVGAGPLRAMGRQALLLLALCATGAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 WDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 WDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 MALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRAS
130 140 150 160 170 180
190 200 210 220
pF1KE0 EERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV
CCDS78 AYLLVI
>>CCDS4428.1 TMED9 gene_id:54732|Hs108|chr5 (235 aa)
initn: 1163 init1: 1163 opt: 1172 Z-score: 1399.1 bits: 266.2 E(32554): 1.3e-71
Smith-Waterman score: 1172; 78.9% identity (91.9% similar) in 223 aa overlap (5-227:15-235)
10 20 30 40 50
pF1KE0 MAGVGAGPLRAMGRQALLLLALCATGAQGLYFHIGETEKRCFIEEIPDET
:.: :.: : ::.: : :: ...::::::::::.::::::::::
CCDS44 MAVELGVLLVRPRPGTGLGRVM-RTLLLVLWL-ATRGSALYFHIGETEKKCFIEEIPDET
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 MVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDH
:::::::::..:::.: . :.:::::: ::::::. ::.:.:::::::::::::::::.:
CCDS44 MVIGNYRTQLYDKQREEYQPATPGLGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 QICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQI
:::::::::...::::: ::::::::::::::.: ::::::::.:::::.:::..:::::
CCDS44 QICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQI
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 QKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV
::::.:::.:::::: :::::::::::::: ::.::. :.::::::::::::::::
CCDS44 QKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMRHLKSFFEAKKLV
180 190 200 210 220 230
>>CCDS78226.1 TMED4 gene_id:222068|Hs108|chr7 (178 aa)
initn: 1188 init1: 880 opt: 880 Z-score: 1054.3 bits: 202.0 E(32554): 2.1e-52
Smith-Waterman score: 1094; 78.4% identity (78.4% similar) in 227 aa overlap (1-227:1-178)
10 20 30 40 50 60
pF1KE0 MAGVGAGPLRAMGRQALLLLALCATGAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 MAGVGAGPLRAMGRQALLLLALCATGAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 WDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 WDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYR
::::::::: ::
CCDS78 MALFAGGKL-------------------------------------------------YR
130
190 200 210 220
pF1KE0 EERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV
:::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 EERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV
140 150 160 170
>>CCDS9840.1 TMED10 gene_id:10972|Hs108|chr14 (219 aa)
initn: 319 init1: 242 opt: 319 Z-score: 386.6 bits: 78.7 E(32554): 3.3e-15
Smith-Waterman score: 376; 34.2% identity (64.1% similar) in 231 aa overlap (1-227:1-218)
10 20 30 40 50
pF1KE0 MAGVGAGPLRAMGRQALLLLALCATGAQ---GLYFHIGETEKRCFIEEIPDETMVIGNYR
:.:... : : : : :: : : . .. ::. . ..:. ::: . .: : :
CCDS98 MSGLSGPPARR-GPFPLALLLLFLLGPRLVLAISFHLPINSRKCLREEIHKDLLVTGAY-
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 TQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSN
.. :.. .. :: :... : :... :.. ...:.:.::.. ..:..:.
CCDS98 -EISDQSG-----GAGGLRSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ST-RMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDY
.: :. .: : ::.. : .:.:: ::: .:: :... :.: : :.: .. :
CCDS98 GTGRIP----DQL-VILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAY
120 130 140 150 160
180 190 200 210 220
pF1KE0 QRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV
.. :::..: :.:::: :::..:: . :: . ::. .:. ::.::::.
CCDS98 MKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE
170 180 190 200 210
>>CCDS9250.1 TMED2 gene_id:10959|Hs108|chr12 (201 aa)
initn: 283 init1: 142 opt: 253 Z-score: 308.8 bits: 64.2 E(32554): 7e-11
Smith-Waterman score: 276; 27.4% identity (59.9% similar) in 212 aa overlap (17-227:9-201)
10 20 30 40 50 60
pF1KE0 MAGVGAGPLRAMGRQALLLLALCATGAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQM
.:: :: :: ..: . : ..::.:.. . :
CCDS92 MVTLAELLVLLAALLAT-VSGYFVSIDAHAEECFFERVTSGT----------
10 20 30 40
70 80 90 100 110
pF1KE0 WDKQKEVFLPSTPG-LGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNST
:. .: . : : . ::. ::.: . . . : :..::..: : ...:. :.
CCDS92 --KMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCF---SN
50 60 70 80 90
120 130 140 150 160 170
pF1KE0 RMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRY
::. .. . .:: . ..... : ..:: :. .: . ...::.:..
CCDS92 RMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEM---INELAVAMTAVKHEQEYMEV
100 110 120 130 140 150
180 190 200 210 220
pF1KE0 REERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV
::. : ...::.::. ::. ....:. . :. .:: :::....:
CCDS92 RERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV
160 170 180 190 200
227 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 04:06:39 2016 done: Mon Nov 7 04:06:39 2016
Total Scan time: 2.220 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]