Result of FASTA (ccds) for
pFN21AE0359
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0359, 582 aa
1>>>pF1KE0359 582 - 582 aa - 582 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1173+/-0.00086; mu= 12.6706+/- 0.052
mean_var=142.3601+/-28.764, 0's: 0 Z-trim(112.7): 30 B-trim: 331 in 1/49
Lambda= 0.107493
statistics sampled from 13388 (13416) to 13388 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.412), width: 16
Scan time: 3.800
The best scores are: opt bits E(32554)
CCDS43493.2 HDAC2 gene_id:3066|Hs108|chr6 ( 488) 3343 529.9 2.9e-150
CCDS360.1 HDAC1 gene_id:3065|Hs108|chr1 ( 482) 2880 458.1 1.2e-128
CCDS4264.1 HDAC3 gene_id:8841|Hs108|chr5 ( 428) 1833 295.6 8.1e-80
CCDS14420.1 HDAC8 gene_id:55869|Hs108|chrX ( 377) 1089 180.2 4e-45
CCDS55449.1 HDAC8 gene_id:55869|Hs108|chrX ( 286) 821 138.6 1e-32
CCDS55451.1 HDAC8 gene_id:55869|Hs108|chrX ( 256) 721 123.0 4.5e-28
CCDS14306.1 HDAC6 gene_id:10013|Hs108|chrX (1215) 389 72.1 4.7e-12
CCDS83163.1 HDAC9 gene_id:9734|Hs108|chr7 (1025) 368 68.8 3.9e-11
CCDS47554.1 HDAC9 gene_id:9734|Hs108|chr7 (1066) 368 68.8 4e-11
CCDS47553.1 HDAC9 gene_id:9734|Hs108|chr7 (1069) 368 68.8 4e-11
>>CCDS43493.2 HDAC2 gene_id:3066|Hs108|chr6 (488 aa)
initn: 3343 init1: 3343 opt: 3343 Z-score: 2811.2 bits: 529.9 E(32554): 2.9e-150
Smith-Waterman score: 3343; 100.0% identity (100.0% similar) in 488 aa overlap (95-582:1-488)
70 80 90 100 110 120
pF1KE0 PFLSRPSRGGSSSSSSSRRRSPVAAVAGEPMAYSQGGGKKKVCYYYDGDIGNYYYGQGHP
::::::::::::::::::::::::::::::
CCDS43 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHP
10 20 30
130 140 150 160 170 180
pF1KE0 MKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSK
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE0 QMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 QMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASG
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE0 FCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 FCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTG
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE0 DLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 DLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGD
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE0 RLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 RLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELP
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE0 YNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 YNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAV
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE0 HEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 HEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEED
400 410 420 430 440 450
550 560 570 580
pF1KE0 KKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP
::::::::::::::::::::::::::::::::::::::
CCDS43 KKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP
460 470 480
>>CCDS360.1 HDAC1 gene_id:3065|Hs108|chr1 (482 aa)
initn: 2924 init1: 2811 opt: 2880 Z-score: 2423.2 bits: 458.1 E(32554): 1.2e-128
Smith-Waterman score: 2880; 85.9% identity (95.0% similar) in 483 aa overlap (95-577:1-478)
70 80 90 100 110 120
pF1KE0 PFLSRPSRGGSSSSSSSRRRSPVAAVAGEPMAYSQGGGKKKVCYYYDGDIGNYYYGQGHP
:: .:: ..:::::::::.::::::::::
CCDS36 MAQTQGT-RRKVCYYYDGDVGNYYYGQGHP
10 20
130 140 150 160 170 180
pF1KE0 MKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSK
::::::::::::::::::::::::::::::.::::::::::.::::::::::::::::::
CCDS36 MKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSK
30 40 50 60 70 80
190 200 210 220 230 240
pF1KE0 QMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASG
::::::::::::::::::::::::::::::.:::::.::::.::::::::::::::::::
CCDS36 QMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASG
90 100 110 120 130 140
250 260 270 280 290 300
pF1KE0 FCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 FCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTG
150 160 170 180 190 200
310 320 330 340 350 360
pF1KE0 DLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGD
::::::::::::::::.:.::::::::: ::::..::::::.::::::::::.::::::
CCDS36 DLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGD
210 220 230 240 250 260
370 380 390 400 410 420
pF1KE0 RLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELP
::::::::.:::::::: ::.::::.:::::::::::::::::::::::::: :::::::
CCDS36 RLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELP
270 280 290 300 310 320
430 440 450 460 470 480
pF1KE0 YNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAV
:::::::::::::::::::::::::: ::.:::::::::::::::::::::::::::::.
CCDS36 YNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAI
330 340 350 360 370 380
490 500 510 520 530 540
pF1KE0 HEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEED
:.::::: .:::::::: .:::::::.:::::::.::::::.: .. :: ::... :..
CCDS36 PEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKK-AKRVKTEDE
390 400 410 420 430 440
550 560 570 580
pF1KE0 KKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP
:.. ..: .: ::.:.:. :: ..::.: :
CCDS36 KEKDPEEKKEVTEEEKTKE---EKPEAKGVKEEVKLA
450 460 470 480
>>CCDS4264.1 HDAC3 gene_id:8841|Hs108|chr5 (428 aa)
initn: 1131 init1: 978 opt: 1833 Z-score: 1546.4 bits: 295.6 E(32554): 8.1e-80
Smith-Waterman score: 1833; 58.8% identity (84.4% similar) in 422 aa overlap (104-523:3-421)
80 90 100 110 120 130
pF1KE0 GSSSSSSSRRRSPVAAVAGEPMAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMT
: : :.:: :.::..:: ::::::::. .:
CCDS42 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALT
10 20 30
140 150 160 170 180 190
pF1KE0 HNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGE
:.:.:.::::.:: ...:..:. ..: ..::..:: ::. . : ::. ..:... ::::.
CCDS42 HSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGD
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE0 DCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVL
::::: ::::::. ::.:. ::..:: . :.:.::::::::::: ::::::::::::.
CCDS42 DCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVI
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE0 AILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYF-PGTGDLRDIGAG
.:::::::: :::::::::::::::.:::: :::::::::::::.:: :::::. ..::
CCDS42 GILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAE
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE0 KGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLT
.:.:: .: :.::::::.:: ..:.:.:..:...:::. .:::::::::. ::::::::.
CCDS42 SGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLS
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE0 VKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYF
..::..::: ::.::.:::.:::::::.:::::::::::.. .. : .::::..:::::
CCDS42 IRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYF
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE0 GPDFKLHISPSN-MTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDE
.::: :: . :. . :::. .:...:.: .::::.:: :::.::.. .: : . : ::
CCDS42 APDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDE
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE0 DGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDK
: ..: . . . .: .:: :.. ...
CCDS42 --ADAEER-GPEENYSRPEAPNEFYDGDHDNDKESDVEI
400 410 420
560 570 580
pF1KE0 KTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP
>>CCDS14420.1 HDAC8 gene_id:55869|Hs108|chrX (377 aa)
initn: 953 init1: 551 opt: 1089 Z-score: 923.6 bits: 180.2 E(32554): 4e-45
Smith-Waterman score: 1089; 43.4% identity (77.1% similar) in 341 aa overlap (127-466:35-374)
100 110 120 130 140 150
pF1KE0 YSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATA
:.: :.:.:. :.:...:.: .:. :.
CCDS14 EEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASM
10 20 30 40 50 60
160 170 180 190 200 210
pF1KE0 EEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGA
:::. .:.: :.. :... .. ... ... ...: :::. .:.:.. :.....:
CCDS14 EEMATFHTDAYLQHLQKVSQEGDDDHPDSIE-YGLGYDCPATEGIFDYAAAIGGATITAA
70 80 90 100 110 120
220 230 240 250 260 270
pF1KE0 VKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGD
: . .:.::.:: :::::.:::::::.:: ::.::.: . .:.::.:.:.::::
CCDS14 QCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGD
130 140 150 160 170 180
280 290 300 310 320 330
pF1KE0 GVEEAFYTTDRVMTVSFHKYGE-YFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQI
:::.:: :..:::::.::.. .::::::. :.: :::.::.:: :..:::.::.: ::
CCDS14 GVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQI
190 200 210 220 230 240
340 350 360 370 380 390
pF1KE0 FKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGG
. ....:.. ..:.::::: :::...:: . ::.: : .::.. . ..: :.:::
CCDS14 CESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGG
250 260 270 280 290 300
400 410 420 430 440 450
pF1KE0 GGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYME
:::.. :.:::::: :.: : . .:.: ...: .:::. :.:.:: ..: :. ..
CCDS14 GGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQ
310 320 330 340 350 360
460 470 480 490 500 510
pF1KE0 KIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEF
.: . . ::.
CCDS14 QILNYIKGNLKHVV
370
>>CCDS55449.1 HDAC8 gene_id:55869|Hs108|chrX (286 aa)
initn: 842 init1: 551 opt: 821 Z-score: 700.6 bits: 138.6 E(32554): 1e-32
Smith-Waterman score: 821; 48.1% identity (78.9% similar) in 237 aa overlap (231-466:47-283)
210 220 230 240 250 260
pF1KE0 LFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLK
: .::. ..:::::::.:: ::.::.: .
CCDS55 VYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRDEASGFCYLNDAVLGILRLRR
20 30 40 50 60 70
270 280 290 300 310
pF1KE0 YHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDLRDIGAGKGKYYAV
.:.::.:.:.:::::::.:: :..:::::.::.. .::::::. :.: :::.::.:
CCDS55 KFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSV
80 90 100 110 120 130
320 330 340 350 360 370
pF1KE0 NFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKC
: :..:::.::.: :: . ....:.. ..:.::::: :::...:: . ::.: : .::
CCDS55 NVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKC
140 150 160 170 180 190
380 390 400 410 420 430
pF1KE0 VEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLH
.. . ..: :.::::::.. :.:::::: :.: : . .:.: ...: .:::. :.
CCDS55 LKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLE
200 210 220 230 240 250
440 450 460 470 480 490
pF1KE0 ISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKR
:.:: ..: :. ...: . . ::.
CCDS55 ITPSCRPDRNEPHRIQQILNYIKGNLKHVV
260 270 280
>>CCDS55451.1 HDAC8 gene_id:55869|Hs108|chrX (256 aa)
initn: 405 init1: 405 opt: 721 Z-score: 617.5 bits: 123.0 E(32554): 4.5e-28
Smith-Waterman score: 721; 46.2% identity (79.5% similar) in 210 aa overlap (127-335:35-243)
100 110 120 130 140 150
pF1KE0 YSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATA
:.: :.:.:. :.:...:.: .:. :.
CCDS55 EEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASM
10 20 30 40 50 60
160 170 180 190 200 210
pF1KE0 EEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGA
:::. .:.: :.. :... .. ... ... ...: :::. .:.:.. :.....:
CCDS55 EEMATFHTDAYLQHLQKVSQEGDDDHPDSIE-YGLGYDCPATEGIFDYAAAIGGATITAA
70 80 90 100 110 120
220 230 240 250 260 270
pF1KE0 VKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGD
: . .:.::.:: :::::.:::::::.:: ::.::.: . .:.::.:.:.::::
CCDS55 QCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGD
130 140 150 160 170 180
280 290 300 310 320 330
pF1KE0 GVEEAFYTTDRVMTVSFHKYGE-YFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQI
:::.:: :..:::::.::.. .::::::. :.: :::.::.:: :..:::.::.: ::
CCDS55 GVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQI
190 200 210 220 230 240
340 350 360 370 380 390
pF1KE0 FKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGG
CCDS55 CERYEPPAPNPGL
250
>>CCDS14306.1 HDAC6 gene_id:10013|Hs108|chrX (1215 aa)
initn: 177 init1: 111 opt: 389 Z-score: 330.0 bits: 72.1 E(32554): 4.7e-12
Smith-Waterman score: 400; 26.8% identity (51.2% similar) in 426 aa overlap (13-404:375-788)
10 20 30 40
pF1KE0 MRSPPCGLLRWFGGPLLASWCRCH-LRFRAFGTSAGWYRAFP
:: :. : . :: : :.::. . .
CCDS14 FDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLG
350 360 370 380 390 400
50 60 70 80
pF1KE0 APPPLLP-PACPSPRDYRPHVS-----LSPF---LSRPS----RGG------SSSSSSSR
: :.: :. : :. . :: : :: : : . : . : .
CCDS14 DPCPMLESPGAPC-RSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGP
410 420 430 440 450 460
90 100 110 120 130 140
pF1KE0 RRSPVAAVAGEPMAYSQGGGKKKVCYYYDGDIGNY--YYGQGHPMKPHRIRMTHNLLLNY
. :: . :. :. : :: .. :. . . :: :.:: : .
CCDS14 WEPPVLPILTWPVLQSRTG------LVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEEL
470 480 490 500 510
150 160 170 180 190 200
pF1KE0 GLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDG
:: . :. :: :. :: ::. ::. . . : .. . :. :: .
CCDS14 GLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICP---S
520 530 540 550 560 570
210 220 230 240 250
pF1KE0 LFEFCQLSTGGS--VAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAI--L
: ::.::.. .. :: .. . :: : :::... : :::. :....:
CCDS14 TFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPG-HHAEQDAACGFCFFNSVAVAARHA
580 590 600 610 620 630
260 270 280 290 300 310
pF1KE0 ELLKYHQ-RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--GEYFP--GTGDLRDIGA
. .. : :.: .: :.:::.:... : :. ::.:.: : .:: : .::
CCDS14 QTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGR
640 650 660 670 680 690
320 330 340 350 360
pF1KE0 GKGKYYAVNFPMRDG--IDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCF
. : ..:: .: . : .: .. .. . ..: :... : :. :: ::
CCDS14 AAGTGFTVNVAW-NGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGC
700 710 720 730 740 750
370 380 390 400 410 420
pF1KE0 NLTVKGHAKCVEVVKTFNLP-LLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDY
... .:.:. .... . .... :::.. ...
CCDS14 QVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPP
760 770 780 790 800 810
430 440 450 460 470 480
pF1KE0 FEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDS
CCDS14 LSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREK
820 830 840 850 860 870
>>CCDS83163.1 HDAC9 gene_id:9734|Hs108|chr7 (1025 aa)
initn: 227 init1: 101 opt: 368 Z-score: 313.4 bits: 68.8 E(32554): 3.9e-11
Smith-Waterman score: 422; 27.0% identity (54.8% similar) in 460 aa overlap (80-496:566-1006)
50 60 70 80 90 100
pF1KE0 ACPSPRDYRPHVSLSPFLSRPSRGGSSSSSSSRRRSPVAAVAGEPMAYS--QGGGKKKVC
: . ::.:.: .: : :. .
CCDS83 LEPTHTRALSVRQAPLAAVGMDGLEKHRLVSRTHSSPAASVLPHPAMDRPLQPGSATGIA
540 550 560 570 580 590
110 120 130 140 150 160
pF1KE0 YYYDGDIGNYYYGQG----HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYH
: : . .. : :: . ::. . : . :: : : . .::. ::. :
CCDS83 Y--DPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVH
600 610 620 630 640 650
170 180 190 200 210
pF1KE0 SDEYIKFLRSIRPDNMSEYSKQM------QRFNVGEDCPVF--DGLFEFCQLSTGGS---
: :. ..: . : . .. . .. :.: . : . :. . .: ..:.
CCDS83 S-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSGAARM
660 670 680 690 700 710
220 230 240 250 260
pF1KE0 -------VAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYH---
.:. : .. .. .:: : :::..: : :::. :..... . :. .
CCDS83 AVGCVIELASKVASGELKNGFAVVRPPG-HHAEESTAMGFCFFNSVAITA-KYLRDQLNI
720 730 740 750 760 770
270 280 290 300 310 320
pF1KE0 QRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--GEYFPGTGDLRDIGAGKGKYYAVN
...: .:.:.:::.:...:::. .. .:.:.: :..:::.: ..:.: :. : .:
CCDS83 SKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPNEVGTGLGEGYNIN
780 790 800 810 820 830
330 340 350 360 370
pF1KE0 FPMRDGID----DESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDR--LGCFNLTVK
. :.: : : . :. :.. : . ..:. :... : :.: : :: ...:.:
CCDS83 IAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVLVSAGFDALEGHTPPLGGYKVTAK
840 850 860 870 880 890
380 390 400 410 420 430
pF1KE0 --GH-AKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEY
:: .: . .. . : . :: : : : . :. : . . ::: :
CCDS83 CFGHLTKQLMTLADGRVVLALEGGHDLT----AICDASEACV--NALLGNEL------EP
900 910 920 930
440 450 460 470 480
pF1KE0 FGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRML--PHA---PGVQMQAIPEDAVHE
.. :. :: :: ::. . . . .:... ....::. :.. :.:.: : .
CCDS83 LAEDI-LHQSP-NMNAVISLQKIIEIQSKYWKSVRMVAVPRGCALAGAQLQEETETVSAL
940 950 960 970 980 990
490 500 510 520 530 540
pF1KE0 DSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKK
: : :.:
CCDS83 ASLTVDVEQPFAQEDSRTAGEPMEEEPAL
1000 1010 1020
>>CCDS47554.1 HDAC9 gene_id:9734|Hs108|chr7 (1066 aa)
initn: 227 init1: 101 opt: 368 Z-score: 313.1 bits: 68.8 E(32554): 4e-11
Smith-Waterman score: 422; 27.0% identity (54.8% similar) in 460 aa overlap (80-496:607-1047)
50 60 70 80 90 100
pF1KE0 ACPSPRDYRPHVSLSPFLSRPSRGGSSSSSSSRRRSPVAAVAGEPMAYS--QGGGKKKVC
: . ::.:.: .: : :. .
CCDS47 LEPTHTRALSVRQAPLAAVGMDGLEKHRLVSRTHSSPAASVLPHPAMDRPLQPGSATGIA
580 590 600 610 620 630
110 120 130 140 150 160
pF1KE0 YYYDGDIGNYYYGQG----HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYH
: : . .. : :: . ::. . : . :: : : . .::. ::. :
CCDS47 Y--DPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVH
640 650 660 670 680 690
170 180 190 200 210
pF1KE0 SDEYIKFLRSIRPDNMSEYSKQM------QRFNVGEDCPVF--DGLFEFCQLSTGGS---
: :. ..: . : . .. . .. :.: . : . :. . .: ..:.
CCDS47 S-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSGAARM
700 710 720 730 740 750
220 230 240 250 260
pF1KE0 -------VAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYH---
.:. : .. .. .:: : :::..: : :::. :..... . :. .
CCDS47 AVGCVIELASKVASGELKNGFAVVRPPG-HHAEESTAMGFCFFNSVAITA-KYLRDQLNI
760 770 780 790 800 810
270 280 290 300 310 320
pF1KE0 QRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--GEYFPGTGDLRDIGAGKGKYYAVN
...: .:.:.:::.:...:::. .. .:.:.: :..:::.: ..:.: :. : .:
CCDS47 SKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPNEVGTGLGEGYNIN
820 830 840 850 860 870
330 340 350 360 370
pF1KE0 FPMRDGID----DESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDR--LGCFNLTVK
. :.: : : . :. :.. : . ..:. :... : :.: : :: ...:.:
CCDS47 IAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVLVSAGFDALEGHTPPLGGYKVTAK
880 890 900 910 920 930
380 390 400 410 420 430
pF1KE0 --GH-AKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEY
:: .: . .. . : . :: : : : . :. : . . ::: :
CCDS47 CFGHLTKQLMTLADGRVVLALEGGHDLT----AICDASEACV--NALLGNEL------EP
940 950 960 970
440 450 460 470 480
pF1KE0 FGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRML--PHA---PGVQMQAIPEDAVHE
.. :. :: :: ::. . . . .:... ....::. :.. :.:.: : .
CCDS47 LAEDI-LHQSP-NMNAVISLQKIIEIQSKYWKSVRMVAVPRGCALAGAQLQEETETVSAL
980 990 1000 1010 1020 1030
490 500 510 520 530 540
pF1KE0 DSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKK
: : :.:
CCDS47 ASLTVDVEQPFAQEDSRTAGEPMEEEPAL
1040 1050 1060
>>CCDS47553.1 HDAC9 gene_id:9734|Hs108|chr7 (1069 aa)
initn: 227 init1: 101 opt: 368 Z-score: 313.1 bits: 68.8 E(32554): 4e-11
Smith-Waterman score: 422; 27.0% identity (54.8% similar) in 460 aa overlap (80-496:610-1050)
50 60 70 80 90 100
pF1KE0 ACPSPRDYRPHVSLSPFLSRPSRGGSSSSSSSRRRSPVAAVAGEPMAYS--QGGGKKKVC
: . ::.:.: .: : :. .
CCDS47 LEPTHTRALSVRQAPLAAVGMDGLEKHRLVSRTHSSPAASVLPHPAMDRPLQPGSATGIA
580 590 600 610 620 630
110 120 130 140 150 160
pF1KE0 YYYDGDIGNYYYGQG----HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYH
: : . .. : :: . ::. . : . :: : : . .::. ::. :
CCDS47 Y--DPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVH
640 650 660 670 680 690
170 180 190 200 210
pF1KE0 SDEYIKFLRSIRPDNMSEYSKQM------QRFNVGEDCPVF--DGLFEFCQLSTGGS---
: :. ..: . : . .. . .. :.: . : . :. . .: ..:.
CCDS47 S-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSGAARM
700 710 720 730 740 750
220 230 240 250 260
pF1KE0 -------VAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYH---
.:. : .. .. .:: : :::..: : :::. :..... . :. .
CCDS47 AVGCVIELASKVASGELKNGFAVVRPPG-HHAEESTAMGFCFFNSVAITA-KYLRDQLNI
760 770 780 790 800 810
270 280 290 300 310 320
pF1KE0 QRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--GEYFPGTGDLRDIGAGKGKYYAVN
...: .:.:.:::.:...:::. .. .:.:.: :..:::.: ..:.: :. : .:
CCDS47 SKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPNEVGTGLGEGYNIN
820 830 840 850 860 870
330 340 350 360 370
pF1KE0 FPMRDGID----DESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDR--LGCFNLTVK
. :.: : : . :. :.. : . ..:. :... : :.: : :: ...:.:
CCDS47 IAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVLVSAGFDALEGHTPPLGGYKVTAK
880 890 900 910 920 930
380 390 400 410 420 430
pF1KE0 --GH-AKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEY
:: .: . .. . : . :: : : : . :. : . . ::: :
CCDS47 CFGHLTKQLMTLADGRVVLALEGGHDLT----AICDASEACV--NALLGNEL------EP
940 950 960 970 980
440 450 460 470 480
pF1KE0 FGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRML--PHA---PGVQMQAIPEDAVHE
.. :. :: :: ::. . . . .:... ....::. :.. :.:.: : .
CCDS47 LAEDI-LHQSP-NMNAVISLQKIIEIQSKYWKSVRMVAVPRGCALAGAQLQEETETVSAL
990 1000 1010 1020 1030 1040
490 500 510 520 530 540
pF1KE0 DSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKK
: : :.:
CCDS47 ASLTVDVEQPFAQEDSRTAGEPMEEEPAL
1050 1060
582 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 04:00:09 2016 done: Mon Nov 7 04:00:10 2016
Total Scan time: 3.800 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]