Result of FASTA (omim) for
pFN21AE0271
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0271, 358 aa
1>>>pF1KE0271 358 - 358 aa - 358 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3661+/-0.000283; mu= 12.7748+/- 0.018
mean_var=102.3163+/-20.243, 0's: 0 Z-trim(121.3): 14 B-trim: 0 in 0/54
Lambda= 0.126795
statistics sampled from 37782 (37796) to 37782 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.777), E-opt: 0.2 (0.443), width: 16
Scan time: 9.820
The best scores are: opt bits E(85289)
XP_005261261 (OMIM: 603294) PREDICTED: germinal-ce (1980) 450 92.6 8.2e-18
NP_003897 (OMIM: 603294) germinal-center associate (1980) 450 92.6 8.2e-18
XP_005261260 (OMIM: 603294) PREDICTED: germinal-ce (1980) 450 92.6 8.2e-18
XP_005261262 (OMIM: 603294) PREDICTED: germinal-ce (1980) 450 92.6 8.2e-18
>>XP_005261261 (OMIM: 603294) PREDICTED: germinal-center (1980 aa)
initn: 397 init1: 159 opt: 450 Z-score: 440.8 bits: 92.6 E(85289): 8.2e-18
Smith-Waterman score: 450; 31.5% identity (58.3% similar) in 333 aa overlap (8-333:634-958)
10 20 30
pF1KE0 MPGCELPVGTCPDMCPAAERAQREREHRLHRLEVVPG
:::: :::: :: .:: . .: .:::::
XP_005 KEKYRLLDQRDRIMRQARVKRTDLDKARTFVGTCLDMCPEKERYMRETRSQLSVFEVVPG
610 620 630 640 650 660
40 50 60 70 80 90
pF1KE0 CRQDPPRADPQRAVKEYSRPAAGKPRPPPSQLRPPSVLLATVRYLAGEVAESADIARAEV
: .: ::::::: .: . .: : .::: :: :. ::. .. .. . . .
XP_005 TDQ----VDHAAAVKEYSRSSADQEEPLPHELRPLPVLSRTMDYLVTQIMDQKEGSLRDW
670 680 690 700 710
100 110 120 130 140 150
pF1KE0 ASFVADRLRAVLLDLALQGAGDAEAAVVLEAALATLLTVVARLGPDAARGPADPVLLQAQ
.:: .: :.. :.. : : .. ..: . . :.. . . : . . .
XP_005 YDFVWNRTRGIRKDITQQHLCDPLTVSLIEKC-TRFHIHCAHFMCEEPMSSFDAKINNEN
720 730 740 750 760 770
160 170 180 190 200 210
pF1KE0 VQEGFGSLRRCYA--RGAGPHPRQPA-FQGLFLLYNLGSVEALHEVLQLPAALRACPPLR
. . . ::.. : :. : . : ::: .: .:.. . :.:: :. :.: ..
XP_005 MTKCLQSLKEMYQDLRNKGVFCASEAEFQGYNVLLSLNKGDILREVQQFHPAVRNSSEVK
780 790 800 810 820 830
220 230 240 250 260 270
pF1KE0 KALAVDAAFREGNAARLFRLLQTLPYLPSCAVQCHVGHARREALA--RFARAFSTPKGQT
:. . ::. .: .:.:.:.:. :: .: ..:. .. :..:: :: . :: ..
XP_005 FAVQAFAALNSNNFVRFFKLVQSASYLNACLLHCYFSQIRKDALRALNFAYTVSTQRSTI
840 850 860 870 880 890
280 290 300 310 320 330
pF1KE0 LPLGFMVNLLALDGLREARDLCQAHGLPL-DGEERVVFLRGRYVE-EGLPPASTCKVLVE
.:: .: .: . .:: :. ::: . :: : . :. ..: ::: . .:..
XP_005 FPLDGVVRMLLFRDCEEATDFLTCHGLTVSDGC--VELNRSAFLEPEGLSK-TRKSVFIT
900 910 920 930 940 950
340 350
pF1KE0 SKLRGRTLEEVVMAEEEDEGTDRPGSPA
::
XP_005 RKLTVSVGEIVNGGPLPPVPRHTPVCSFNSQNKYIGESLAAELPVSTQRPGSDTVGGGRG
960 970 980 990 1000 1010
>>NP_003897 (OMIM: 603294) germinal-center associated nu (1980 aa)
initn: 397 init1: 159 opt: 450 Z-score: 440.8 bits: 92.6 E(85289): 8.2e-18
Smith-Waterman score: 450; 31.5% identity (58.3% similar) in 333 aa overlap (8-333:634-958)
10 20 30
pF1KE0 MPGCELPVGTCPDMCPAAERAQREREHRLHRLEVVPG
:::: :::: :: .:: . .: .:::::
NP_003 KEKYRLLDQRDRIMRQARVKRTDLDKARTFVGTCLDMCPEKERYMRETRSQLSVFEVVPG
610 620 630 640 650 660
40 50 60 70 80 90
pF1KE0 CRQDPPRADPQRAVKEYSRPAAGKPRPPPSQLRPPSVLLATVRYLAGEVAESADIARAEV
: .: ::::::: .: . .: : .::: :: :. ::. .. .. . . .
NP_003 TDQ----VDHAAAVKEYSRSSADQEEPLPHELRPLPVLSRTMDYLVTQIMDQKEGSLRDW
670 680 690 700 710
100 110 120 130 140 150
pF1KE0 ASFVADRLRAVLLDLALQGAGDAEAAVVLEAALATLLTVVARLGPDAARGPADPVLLQAQ
.:: .: :.. :.. : : .. ..: . . :.. . . : . . .
NP_003 YDFVWNRTRGIRKDITQQHLCDPLTVSLIEKC-TRFHIHCAHFMCEEPMSSFDAKINNEN
720 730 740 750 760 770
160 170 180 190 200 210
pF1KE0 VQEGFGSLRRCYA--RGAGPHPRQPA-FQGLFLLYNLGSVEALHEVLQLPAALRACPPLR
. . . ::.. : :. : . : ::: .: .:.. . :.:: :. :.: ..
NP_003 MTKCLQSLKEMYQDLRNKGVFCASEAEFQGYNVLLSLNKGDILREVQQFHPAVRNSSEVK
780 790 800 810 820 830
220 230 240 250 260 270
pF1KE0 KALAVDAAFREGNAARLFRLLQTLPYLPSCAVQCHVGHARREALA--RFARAFSTPKGQT
:. . ::. .: .:.:.:.:. :: .: ..:. .. :..:: :: . :: ..
NP_003 FAVQAFAALNSNNFVRFFKLVQSASYLNACLLHCYFSQIRKDALRALNFAYTVSTQRSTI
840 850 860 870 880 890
280 290 300 310 320 330
pF1KE0 LPLGFMVNLLALDGLREARDLCQAHGLPL-DGEERVVFLRGRYVE-EGLPPASTCKVLVE
.:: .: .: . .:: :. ::: . :: : . :. ..: ::: . .:..
NP_003 FPLDGVVRMLLFRDCEEATDFLTCHGLTVSDGC--VELNRSAFLEPEGLSK-TRKSVFIT
900 910 920 930 940 950
340 350
pF1KE0 SKLRGRTLEEVVMAEEEDEGTDRPGSPA
::
NP_003 RKLTVSVGEIVNGGPLPPVPRHTPVCSFNSQNKYIGESLAAELPVSTQRPGSDTVGGGRG
960 970 980 990 1000 1010
>>XP_005261260 (OMIM: 603294) PREDICTED: germinal-center (1980 aa)
initn: 397 init1: 159 opt: 450 Z-score: 440.8 bits: 92.6 E(85289): 8.2e-18
Smith-Waterman score: 450; 31.5% identity (58.3% similar) in 333 aa overlap (8-333:634-958)
10 20 30
pF1KE0 MPGCELPVGTCPDMCPAAERAQREREHRLHRLEVVPG
:::: :::: :: .:: . .: .:::::
XP_005 KEKYRLLDQRDRIMRQARVKRTDLDKARTFVGTCLDMCPEKERYMRETRSQLSVFEVVPG
610 620 630 640 650 660
40 50 60 70 80 90
pF1KE0 CRQDPPRADPQRAVKEYSRPAAGKPRPPPSQLRPPSVLLATVRYLAGEVAESADIARAEV
: .: ::::::: .: . .: : .::: :: :. ::. .. .. . . .
XP_005 TDQ----VDHAAAVKEYSRSSADQEEPLPHELRPLPVLSRTMDYLVTQIMDQKEGSLRDW
670 680 690 700 710
100 110 120 130 140 150
pF1KE0 ASFVADRLRAVLLDLALQGAGDAEAAVVLEAALATLLTVVARLGPDAARGPADPVLLQAQ
.:: .: :.. :.. : : .. ..: . . :.. . . : . . .
XP_005 YDFVWNRTRGIRKDITQQHLCDPLTVSLIEKC-TRFHIHCAHFMCEEPMSSFDAKINNEN
720 730 740 750 760 770
160 170 180 190 200 210
pF1KE0 VQEGFGSLRRCYA--RGAGPHPRQPA-FQGLFLLYNLGSVEALHEVLQLPAALRACPPLR
. . . ::.. : :. : . : ::: .: .:.. . :.:: :. :.: ..
XP_005 MTKCLQSLKEMYQDLRNKGVFCASEAEFQGYNVLLSLNKGDILREVQQFHPAVRNSSEVK
780 790 800 810 820 830
220 230 240 250 260 270
pF1KE0 KALAVDAAFREGNAARLFRLLQTLPYLPSCAVQCHVGHARREALA--RFARAFSTPKGQT
:. . ::. .: .:.:.:.:. :: .: ..:. .. :..:: :: . :: ..
XP_005 FAVQAFAALNSNNFVRFFKLVQSASYLNACLLHCYFSQIRKDALRALNFAYTVSTQRSTI
840 850 860 870 880 890
280 290 300 310 320 330
pF1KE0 LPLGFMVNLLALDGLREARDLCQAHGLPL-DGEERVVFLRGRYVE-EGLPPASTCKVLVE
.:: .: .: . .:: :. ::: . :: : . :. ..: ::: . .:..
XP_005 FPLDGVVRMLLFRDCEEATDFLTCHGLTVSDGC--VELNRSAFLEPEGLSK-TRKSVFIT
900 910 920 930 940 950
340 350
pF1KE0 SKLRGRTLEEVVMAEEEDEGTDRPGSPA
::
XP_005 RKLTVSVGEIVNGGPLPPVPRHTPVCSFNSQNKYIGESLAAELPVSTQRPGSDTVGGGRG
960 970 980 990 1000 1010
>>XP_005261262 (OMIM: 603294) PREDICTED: germinal-center (1980 aa)
initn: 397 init1: 159 opt: 450 Z-score: 440.8 bits: 92.6 E(85289): 8.2e-18
Smith-Waterman score: 450; 31.5% identity (58.3% similar) in 333 aa overlap (8-333:634-958)
10 20 30
pF1KE0 MPGCELPVGTCPDMCPAAERAQREREHRLHRLEVVPG
:::: :::: :: .:: . .: .:::::
XP_005 KEKYRLLDQRDRIMRQARVKRTDLDKARTFVGTCLDMCPEKERYMRETRSQLSVFEVVPG
610 620 630 640 650 660
40 50 60 70 80 90
pF1KE0 CRQDPPRADPQRAVKEYSRPAAGKPRPPPSQLRPPSVLLATVRYLAGEVAESADIARAEV
: .: ::::::: .: . .: : .::: :: :. ::. .. .. . . .
XP_005 TDQ----VDHAAAVKEYSRSSADQEEPLPHELRPLPVLSRTMDYLVTQIMDQKEGSLRDW
670 680 690 700 710
100 110 120 130 140 150
pF1KE0 ASFVADRLRAVLLDLALQGAGDAEAAVVLEAALATLLTVVARLGPDAARGPADPVLLQAQ
.:: .: :.. :.. : : .. ..: . . :.. . . : . . .
XP_005 YDFVWNRTRGIRKDITQQHLCDPLTVSLIEKC-TRFHIHCAHFMCEEPMSSFDAKINNEN
720 730 740 750 760 770
160 170 180 190 200 210
pF1KE0 VQEGFGSLRRCYA--RGAGPHPRQPA-FQGLFLLYNLGSVEALHEVLQLPAALRACPPLR
. . . ::.. : :. : . : ::: .: .:.. . :.:: :. :.: ..
XP_005 MTKCLQSLKEMYQDLRNKGVFCASEAEFQGYNVLLSLNKGDILREVQQFHPAVRNSSEVK
780 790 800 810 820 830
220 230 240 250 260 270
pF1KE0 KALAVDAAFREGNAARLFRLLQTLPYLPSCAVQCHVGHARREALA--RFARAFSTPKGQT
:. . ::. .: .:.:.:.:. :: .: ..:. .. :..:: :: . :: ..
XP_005 FAVQAFAALNSNNFVRFFKLVQSASYLNACLLHCYFSQIRKDALRALNFAYTVSTQRSTI
840 850 860 870 880 890
280 290 300 310 320 330
pF1KE0 LPLGFMVNLLALDGLREARDLCQAHGLPL-DGEERVVFLRGRYVE-EGLPPASTCKVLVE
.:: .: .: . .:: :. ::: . :: : . :. ..: ::: . .:..
XP_005 FPLDGVVRMLLFRDCEEATDFLTCHGLTVSDGC--VELNRSAFLEPEGLSK-TRKSVFIT
900 910 920 930 940 950
340 350
pF1KE0 SKLRGRTLEEVVMAEEEDEGTDRPGSPA
::
XP_005 RKLTVSVGEIVNGGPLPPVPRHTPVCSFNSQNKYIGESLAAELPVSTQRPGSDTVGGGRG
960 970 980 990 1000 1010
358 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 04:07:44 2016 done: Mon Nov 7 04:07:45 2016
Total Scan time: 9.820 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]