Result of FASTA (omim) for
pFN21AE0089
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0089, 708 aa
1>>>pF1KE0089 708 - 708 aa - 708 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0513+/-0.000374; mu= 22.6295+/- 0.023
mean_var=84.0387+/-16.730, 0's: 0 Z-trim(114.9): 81 B-trim: 436 in 1/50
Lambda= 0.139905
statistics sampled from 24991 (25072) to 24991 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.294), width: 16
Scan time: 9.670
The best scores are: opt bits E(85289)
XP_005269983 (OMIM: 611749) PREDICTED: ubiquitin t ( 708) 4887 996.7 0
NP_060050 (OMIM: 611749) ubiquitin thioesterase ZR ( 708) 4887 996.7 0
XP_016871846 (OMIM: 611749) PREDICTED: ubiquitin t ( 708) 4887 996.7 0
XP_005269982 (OMIM: 611749) PREDICTED: ubiquitin t ( 734) 4887 996.7 0
XP_006717970 (OMIM: 611749) PREDICTED: ubiquitin t ( 734) 4887 996.7 0
XP_016871847 (OMIM: 611749) PREDICTED: ubiquitin t ( 382) 2618 538.4 1.9e-152
XP_011538189 (OMIM: 611749) PREDICTED: ubiquitin t ( 248) 1610 334.8 2.5e-91
XP_011534398 (OMIM: 191163,616744) PREDICTED: tumo ( 689) 267 64.2 2e-09
NP_001257437 (OMIM: 191163,616744) tumor necrosis ( 790) 267 64.2 2.2e-09
NP_006281 (OMIM: 191163,616744) tumor necrosis fac ( 790) 267 64.2 2.2e-09
XP_011534397 (OMIM: 191163,616744) PREDICTED: tumo ( 790) 267 64.2 2.2e-09
XP_005267176 (OMIM: 191163,616744) PREDICTED: tumo ( 790) 267 64.2 2.2e-09
NP_001257436 (OMIM: 191163,616744) tumor necrosis ( 790) 267 64.2 2.2e-09
XP_016857340 (OMIM: 611748) PREDICTED: OTU domain- ( 714) 244 59.5 5.2e-08
XP_016857339 (OMIM: 611748) PREDICTED: OTU domain- ( 764) 244 59.6 5.4e-08
XP_011508089 (OMIM: 611748) PREDICTED: OTU domain- ( 773) 244 59.6 5.5e-08
XP_011508088 (OMIM: 611748) PREDICTED: OTU domain- ( 773) 244 59.6 5.5e-08
XP_011508090 (OMIM: 611748) PREDICTED: OTU domain- ( 773) 244 59.6 5.5e-08
NP_064590 (OMIM: 611748) OTU domain-containing pro ( 843) 244 59.6 5.8e-08
XP_011508086 (OMIM: 611748) PREDICTED: OTU domain- ( 852) 244 59.6 5.9e-08
XP_011508084 (OMIM: 611748) PREDICTED: OTU domain- ( 852) 244 59.6 5.9e-08
XP_011508085 (OMIM: 611748) PREDICTED: OTU domain- ( 852) 244 59.6 5.9e-08
XP_011508087 (OMIM: 611748) PREDICTED: OTU domain- ( 852) 244 59.6 5.9e-08
NP_001316836 (OMIM: 612024) OTU domain-containing ( 425) 234 57.3 1.5e-07
NP_570971 (OMIM: 612024) OTU domain-containing pro ( 926) 234 57.6 2.5e-07
XP_016860112 (OMIM: 601181,608033) PREDICTED: E3 S (2807) 168 44.8 0.0057
XP_011509878 (OMIM: 601181,608033) PREDICTED: E3 S (3199) 168 44.8 0.0062
NP_006258 (OMIM: 601181,608033) E3 SUMO-protein li (3224) 168 44.8 0.0062
XP_005264061 (OMIM: 601181,608033) PREDICTED: E3 S (3232) 168 44.8 0.0063
XP_005264062 (OMIM: 601181,608033) PREDICTED: E3 S (3232) 168 44.8 0.0063
XP_005264060 (OMIM: 601181,608033) PREDICTED: E3 S (3250) 168 44.8 0.0063
XP_011509877 (OMIM: 601181,608033) PREDICTED: E3 S (3257) 168 44.8 0.0063
XP_005264059 (OMIM: 601181,608033) PREDICTED: E3 S (3258) 168 44.8 0.0063
>>XP_005269983 (OMIM: 611749) PREDICTED: ubiquitin thioe (708 aa)
initn: 4887 init1: 4887 opt: 4887 Z-score: 5329.6 bits: 996.7 E(85289): 0
Smith-Waterman score: 4887; 100.0% identity (100.0% similar) in 708 aa overlap (1-708:1-708)
10 20 30 40 50 60
pF1KE0 MSERGIKWACEYCTYENWPSAIKCTMCRAQRPSGTIITEDPFKSGSSDVGRDWDPSSTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSERGIKWACEYCTYENWPSAIKCTMCRAQRPSGTIITEDPFKSGSSDVGRDWDPSSTEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GSSPLICPDSSARPRVKSSYSMENANKWSCHMCTYLNWPRAIRCTQCLSQRRTRSPTESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSSPLICPDSSARPRVKSSYSMENANKWSCHMCTYLNWPRAIRCTQCLSQRRTRSPTESP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QSSGSGSRPVAFSVDPCEEYNDRNKLNTRTQHWTCSVCTYENWAKAKRCVVCDHPRPNNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSSGSGSRPVAFSVDPCEEYNDRNKLNTRTQHWTCSVCTYENWAKAKRCVVCDHPRPNNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 EAIELAETEEASSIINEQDRARWRGSCSSGNSQRRSPPATKRDSEVKMDFQRIELAGAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAIELAETEEASSIINEQDRARWRGSCSSGNSQRRSPPATKRDSEVKMDFQRIELAGAVG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SKEELEVDFKKLKQIKNRMKKTDWLFLNACVGVVEGDLAAIEAYKSSGGDIARQLTADEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKEELEVDFKKLKQIKNRMKKTDWLFLNACVGVVEGDLAAIEAYKSSGGDIARQLTADEV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 RLLNRPSAFDVGYTLVHLAIRFQRQDMLAILLTEVSQQAAKCIPAMVCPELTEQIRREIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLLNRPSAFDVGYTLVHLAIRFQRQDMLAILLTEVSQQAAKCIPAMVCPELTEQIRREIA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 ASLHQRKGDFACYFLTDLVTFTLPADIEDLPPTVQEKLFDEVLDRDVQKELEEESPIINW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASLHQRKGDFACYFLTDLVTFTLPADIEDLPPTVQEKLFDEVLDRDVQKELEEESPIINW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 SLELATRLDSRLYALWNRTAGDCLLDSVLQATWGIYDKDSVLRKALHDSLHDCSHWFYTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLELATRLDSRLYALWNRTAGDCLLDSVLQATWGIYDKDSVLRKALHDSLHDCSHWFYTR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 WKDWESWYSQSFGLHFSLREEQWQEDWAFILSLASQPGASLEQTHIFVLAHILRRPIIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WKDWESWYSQSFGLHFSLREEQWQEDWAFILSLASQPGASLEQTHIFVLAHILRRPIIVY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 GVKYYKSFRGETLGYTRFQGVYLPLLWEQSFCWKSPIALGYTRGHFSALVAMENDGYGNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GVKYYKSFRGETLGYTRFQGVYLPLLWEQSFCWKSPIALGYTRGHFSALVAMENDGYGNR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 GAGANLNTDDDVTITFLPLVDSERKLLHVHFLSAQELGNEEQQEKLLREWLDCCVTEGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAGANLNTDDDVTITFLPLVDSERKLLHVHFLSAQELGNEEQQEKLLREWLDCCVTEGGV
610 620 630 640 650 660
670 680 690 700
pF1KE0 LVAMQKSSRRRNHPLVTQMVEKWLDRYRQIRPCTSLSDGEEDEDDEDE
::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVAMQKSSRRRNHPLVTQMVEKWLDRYRQIRPCTSLSDGEEDEDDEDE
670 680 690 700
>>NP_060050 (OMIM: 611749) ubiquitin thioesterase ZRANB1 (708 aa)
initn: 4887 init1: 4887 opt: 4887 Z-score: 5329.6 bits: 996.7 E(85289): 0
Smith-Waterman score: 4887; 100.0% identity (100.0% similar) in 708 aa overlap (1-708:1-708)
10 20 30 40 50 60
pF1KE0 MSERGIKWACEYCTYENWPSAIKCTMCRAQRPSGTIITEDPFKSGSSDVGRDWDPSSTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MSERGIKWACEYCTYENWPSAIKCTMCRAQRPSGTIITEDPFKSGSSDVGRDWDPSSTEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GSSPLICPDSSARPRVKSSYSMENANKWSCHMCTYLNWPRAIRCTQCLSQRRTRSPTESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GSSPLICPDSSARPRVKSSYSMENANKWSCHMCTYLNWPRAIRCTQCLSQRRTRSPTESP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QSSGSGSRPVAFSVDPCEEYNDRNKLNTRTQHWTCSVCTYENWAKAKRCVVCDHPRPNNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QSSGSGSRPVAFSVDPCEEYNDRNKLNTRTQHWTCSVCTYENWAKAKRCVVCDHPRPNNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 EAIELAETEEASSIINEQDRARWRGSCSSGNSQRRSPPATKRDSEVKMDFQRIELAGAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EAIELAETEEASSIINEQDRARWRGSCSSGNSQRRSPPATKRDSEVKMDFQRIELAGAVG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SKEELEVDFKKLKQIKNRMKKTDWLFLNACVGVVEGDLAAIEAYKSSGGDIARQLTADEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SKEELEVDFKKLKQIKNRMKKTDWLFLNACVGVVEGDLAAIEAYKSSGGDIARQLTADEV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 RLLNRPSAFDVGYTLVHLAIRFQRQDMLAILLTEVSQQAAKCIPAMVCPELTEQIRREIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RLLNRPSAFDVGYTLVHLAIRFQRQDMLAILLTEVSQQAAKCIPAMVCPELTEQIRREIA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 ASLHQRKGDFACYFLTDLVTFTLPADIEDLPPTVQEKLFDEVLDRDVQKELEEESPIINW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ASLHQRKGDFACYFLTDLVTFTLPADIEDLPPTVQEKLFDEVLDRDVQKELEEESPIINW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 SLELATRLDSRLYALWNRTAGDCLLDSVLQATWGIYDKDSVLRKALHDSLHDCSHWFYTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SLELATRLDSRLYALWNRTAGDCLLDSVLQATWGIYDKDSVLRKALHDSLHDCSHWFYTR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 WKDWESWYSQSFGLHFSLREEQWQEDWAFILSLASQPGASLEQTHIFVLAHILRRPIIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 WKDWESWYSQSFGLHFSLREEQWQEDWAFILSLASQPGASLEQTHIFVLAHILRRPIIVY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 GVKYYKSFRGETLGYTRFQGVYLPLLWEQSFCWKSPIALGYTRGHFSALVAMENDGYGNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GVKYYKSFRGETLGYTRFQGVYLPLLWEQSFCWKSPIALGYTRGHFSALVAMENDGYGNR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 GAGANLNTDDDVTITFLPLVDSERKLLHVHFLSAQELGNEEQQEKLLREWLDCCVTEGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GAGANLNTDDDVTITFLPLVDSERKLLHVHFLSAQELGNEEQQEKLLREWLDCCVTEGGV
610 620 630 640 650 660
670 680 690 700
pF1KE0 LVAMQKSSRRRNHPLVTQMVEKWLDRYRQIRPCTSLSDGEEDEDDEDE
::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LVAMQKSSRRRNHPLVTQMVEKWLDRYRQIRPCTSLSDGEEDEDDEDE
670 680 690 700
>>XP_016871846 (OMIM: 611749) PREDICTED: ubiquitin thioe (708 aa)
initn: 4887 init1: 4887 opt: 4887 Z-score: 5329.6 bits: 996.7 E(85289): 0
Smith-Waterman score: 4887; 100.0% identity (100.0% similar) in 708 aa overlap (1-708:1-708)
10 20 30 40 50 60
pF1KE0 MSERGIKWACEYCTYENWPSAIKCTMCRAQRPSGTIITEDPFKSGSSDVGRDWDPSSTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSERGIKWACEYCTYENWPSAIKCTMCRAQRPSGTIITEDPFKSGSSDVGRDWDPSSTEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GSSPLICPDSSARPRVKSSYSMENANKWSCHMCTYLNWPRAIRCTQCLSQRRTRSPTESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSPLICPDSSARPRVKSSYSMENANKWSCHMCTYLNWPRAIRCTQCLSQRRTRSPTESP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QSSGSGSRPVAFSVDPCEEYNDRNKLNTRTQHWTCSVCTYENWAKAKRCVVCDHPRPNNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSSGSGSRPVAFSVDPCEEYNDRNKLNTRTQHWTCSVCTYENWAKAKRCVVCDHPRPNNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 EAIELAETEEASSIINEQDRARWRGSCSSGNSQRRSPPATKRDSEVKMDFQRIELAGAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAIELAETEEASSIINEQDRARWRGSCSSGNSQRRSPPATKRDSEVKMDFQRIELAGAVG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SKEELEVDFKKLKQIKNRMKKTDWLFLNACVGVVEGDLAAIEAYKSSGGDIARQLTADEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKEELEVDFKKLKQIKNRMKKTDWLFLNACVGVVEGDLAAIEAYKSSGGDIARQLTADEV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 RLLNRPSAFDVGYTLVHLAIRFQRQDMLAILLTEVSQQAAKCIPAMVCPELTEQIRREIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLLNRPSAFDVGYTLVHLAIRFQRQDMLAILLTEVSQQAAKCIPAMVCPELTEQIRREIA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 ASLHQRKGDFACYFLTDLVTFTLPADIEDLPPTVQEKLFDEVLDRDVQKELEEESPIINW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLHQRKGDFACYFLTDLVTFTLPADIEDLPPTVQEKLFDEVLDRDVQKELEEESPIINW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 SLELATRLDSRLYALWNRTAGDCLLDSVLQATWGIYDKDSVLRKALHDSLHDCSHWFYTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLELATRLDSRLYALWNRTAGDCLLDSVLQATWGIYDKDSVLRKALHDSLHDCSHWFYTR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 WKDWESWYSQSFGLHFSLREEQWQEDWAFILSLASQPGASLEQTHIFVLAHILRRPIIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WKDWESWYSQSFGLHFSLREEQWQEDWAFILSLASQPGASLEQTHIFVLAHILRRPIIVY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 GVKYYKSFRGETLGYTRFQGVYLPLLWEQSFCWKSPIALGYTRGHFSALVAMENDGYGNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVKYYKSFRGETLGYTRFQGVYLPLLWEQSFCWKSPIALGYTRGHFSALVAMENDGYGNR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 GAGANLNTDDDVTITFLPLVDSERKLLHVHFLSAQELGNEEQQEKLLREWLDCCVTEGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAGANLNTDDDVTITFLPLVDSERKLLHVHFLSAQELGNEEQQEKLLREWLDCCVTEGGV
610 620 630 640 650 660
670 680 690 700
pF1KE0 LVAMQKSSRRRNHPLVTQMVEKWLDRYRQIRPCTSLSDGEEDEDDEDE
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVAMQKSSRRRNHPLVTQMVEKWLDRYRQIRPCTSLSDGEEDEDDEDE
670 680 690 700
>>XP_005269982 (OMIM: 611749) PREDICTED: ubiquitin thioe (734 aa)
initn: 4887 init1: 4887 opt: 4887 Z-score: 5329.4 bits: 996.7 E(85289): 0
Smith-Waterman score: 4887; 100.0% identity (100.0% similar) in 708 aa overlap (1-708:27-734)
10 20 30
pF1KE0 MSERGIKWACEYCTYENWPSAIKCTMCRAQRPSG
::::::::::::::::::::::::::::::::::
XP_005 MCKVEVIAWELKSYFLPDTAHFKKCTMSERGIKWACEYCTYENWPSAIKCTMCRAQRPSG
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE0 TIITEDPFKSGSSDVGRDWDPSSTEGGSSPLICPDSSARPRVKSSYSMENANKWSCHMCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIITEDPFKSGSSDVGRDWDPSSTEGGSSPLICPDSSARPRVKSSYSMENANKWSCHMCT
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 YLNWPRAIRCTQCLSQRRTRSPTESPQSSGSGSRPVAFSVDPCEEYNDRNKLNTRTQHWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLNWPRAIRCTQCLSQRRTRSPTESPQSSGSGSRPVAFSVDPCEEYNDRNKLNTRTQHWT
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 CSVCTYENWAKAKRCVVCDHPRPNNIEAIELAETEEASSIINEQDRARWRGSCSSGNSQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CSVCTYENWAKAKRCVVCDHPRPNNIEAIELAETEEASSIINEQDRARWRGSCSSGNSQR
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 RSPPATKRDSEVKMDFQRIELAGAVGSKEELEVDFKKLKQIKNRMKKTDWLFLNACVGVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSPPATKRDSEVKMDFQRIELAGAVGSKEELEVDFKKLKQIKNRMKKTDWLFLNACVGVV
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 EGDLAAIEAYKSSGGDIARQLTADEVRLLNRPSAFDVGYTLVHLAIRFQRQDMLAILLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGDLAAIEAYKSSGGDIARQLTADEVRLLNRPSAFDVGYTLVHLAIRFQRQDMLAILLTE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE0 VSQQAAKCIPAMVCPELTEQIRREIAASLHQRKGDFACYFLTDLVTFTLPADIEDLPPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSQQAAKCIPAMVCPELTEQIRREIAASLHQRKGDFACYFLTDLVTFTLPADIEDLPPTV
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE0 QEKLFDEVLDRDVQKELEEESPIINWSLELATRLDSRLYALWNRTAGDCLLDSVLQATWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEKLFDEVLDRDVQKELEEESPIINWSLELATRLDSRLYALWNRTAGDCLLDSVLQATWG
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE0 IYDKDSVLRKALHDSLHDCSHWFYTRWKDWESWYSQSFGLHFSLREEQWQEDWAFILSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYDKDSVLRKALHDSLHDCSHWFYTRWKDWESWYSQSFGLHFSLREEQWQEDWAFILSLA
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE0 SQPGASLEQTHIFVLAHILRRPIIVYGVKYYKSFRGETLGYTRFQGVYLPLLWEQSFCWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQPGASLEQTHIFVLAHILRRPIIVYGVKYYKSFRGETLGYTRFQGVYLPLLWEQSFCWK
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE0 SPIALGYTRGHFSALVAMENDGYGNRGAGANLNTDDDVTITFLPLVDSERKLLHVHFLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPIALGYTRGHFSALVAMENDGYGNRGAGANLNTDDDVTITFLPLVDSERKLLHVHFLSA
610 620 630 640 650 660
640 650 660 670 680 690
pF1KE0 QELGNEEQQEKLLREWLDCCVTEGGVLVAMQKSSRRRNHPLVTQMVEKWLDRYRQIRPCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QELGNEEQQEKLLREWLDCCVTEGGVLVAMQKSSRRRNHPLVTQMVEKWLDRYRQIRPCT
670 680 690 700 710 720
700
pF1KE0 SLSDGEEDEDDEDE
::::::::::::::
XP_005 SLSDGEEDEDDEDE
730
>>XP_006717970 (OMIM: 611749) PREDICTED: ubiquitin thioe (734 aa)
initn: 4887 init1: 4887 opt: 4887 Z-score: 5329.4 bits: 996.7 E(85289): 0
Smith-Waterman score: 4887; 100.0% identity (100.0% similar) in 708 aa overlap (1-708:27-734)
10 20 30
pF1KE0 MSERGIKWACEYCTYENWPSAIKCTMCRAQRPSG
::::::::::::::::::::::::::::::::::
XP_006 MCKVEVIAWELKSYFLPDTAHFKKCTMSERGIKWACEYCTYENWPSAIKCTMCRAQRPSG
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE0 TIITEDPFKSGSSDVGRDWDPSSTEGGSSPLICPDSSARPRVKSSYSMENANKWSCHMCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TIITEDPFKSGSSDVGRDWDPSSTEGGSSPLICPDSSARPRVKSSYSMENANKWSCHMCT
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 YLNWPRAIRCTQCLSQRRTRSPTESPQSSGSGSRPVAFSVDPCEEYNDRNKLNTRTQHWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLNWPRAIRCTQCLSQRRTRSPTESPQSSGSGSRPVAFSVDPCEEYNDRNKLNTRTQHWT
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 CSVCTYENWAKAKRCVVCDHPRPNNIEAIELAETEEASSIINEQDRARWRGSCSSGNSQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CSVCTYENWAKAKRCVVCDHPRPNNIEAIELAETEEASSIINEQDRARWRGSCSSGNSQR
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 RSPPATKRDSEVKMDFQRIELAGAVGSKEELEVDFKKLKQIKNRMKKTDWLFLNACVGVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSPPATKRDSEVKMDFQRIELAGAVGSKEELEVDFKKLKQIKNRMKKTDWLFLNACVGVV
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 EGDLAAIEAYKSSGGDIARQLTADEVRLLNRPSAFDVGYTLVHLAIRFQRQDMLAILLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGDLAAIEAYKSSGGDIARQLTADEVRLLNRPSAFDVGYTLVHLAIRFQRQDMLAILLTE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE0 VSQQAAKCIPAMVCPELTEQIRREIAASLHQRKGDFACYFLTDLVTFTLPADIEDLPPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSQQAAKCIPAMVCPELTEQIRREIAASLHQRKGDFACYFLTDLVTFTLPADIEDLPPTV
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE0 QEKLFDEVLDRDVQKELEEESPIINWSLELATRLDSRLYALWNRTAGDCLLDSVLQATWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QEKLFDEVLDRDVQKELEEESPIINWSLELATRLDSRLYALWNRTAGDCLLDSVLQATWG
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE0 IYDKDSVLRKALHDSLHDCSHWFYTRWKDWESWYSQSFGLHFSLREEQWQEDWAFILSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IYDKDSVLRKALHDSLHDCSHWFYTRWKDWESWYSQSFGLHFSLREEQWQEDWAFILSLA
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE0 SQPGASLEQTHIFVLAHILRRPIIVYGVKYYKSFRGETLGYTRFQGVYLPLLWEQSFCWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQPGASLEQTHIFVLAHILRRPIIVYGVKYYKSFRGETLGYTRFQGVYLPLLWEQSFCWK
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE0 SPIALGYTRGHFSALVAMENDGYGNRGAGANLNTDDDVTITFLPLVDSERKLLHVHFLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPIALGYTRGHFSALVAMENDGYGNRGAGANLNTDDDVTITFLPLVDSERKLLHVHFLSA
610 620 630 640 650 660
640 650 660 670 680 690
pF1KE0 QELGNEEQQEKLLREWLDCCVTEGGVLVAMQKSSRRRNHPLVTQMVEKWLDRYRQIRPCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QELGNEEQQEKLLREWLDCCVTEGGVLVAMQKSSRRRNHPLVTQMVEKWLDRYRQIRPCT
670 680 690 700 710 720
700
pF1KE0 SLSDGEEDEDDEDE
::::::::::::::
XP_006 SLSDGEEDEDDEDE
730
>>XP_016871847 (OMIM: 611749) PREDICTED: ubiquitin thioe (382 aa)
initn: 2618 init1: 2618 opt: 2618 Z-score: 2857.9 bits: 538.4 E(85289): 1.9e-152
Smith-Waterman score: 2618; 100.0% identity (100.0% similar) in 382 aa overlap (327-708:1-382)
300 310 320 330 340 350
pF1KE0 ADEVRLLNRPSAFDVGYTLVHLAIRFQRQDMLAILLTEVSQQAAKCIPAMVCPELTEQIR
::::::::::::::::::::::::::::::
XP_016 MLAILLTEVSQQAAKCIPAMVCPELTEQIR
10 20 30
360 370 380 390 400 410
pF1KE0 REIAASLHQRKGDFACYFLTDLVTFTLPADIEDLPPTVQEKLFDEVLDRDVQKELEEESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REIAASLHQRKGDFACYFLTDLVTFTLPADIEDLPPTVQEKLFDEVLDRDVQKELEEESP
40 50 60 70 80 90
420 430 440 450 460 470
pF1KE0 IINWSLELATRLDSRLYALWNRTAGDCLLDSVLQATWGIYDKDSVLRKALHDSLHDCSHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IINWSLELATRLDSRLYALWNRTAGDCLLDSVLQATWGIYDKDSVLRKALHDSLHDCSHW
100 110 120 130 140 150
480 490 500 510 520 530
pF1KE0 FYTRWKDWESWYSQSFGLHFSLREEQWQEDWAFILSLASQPGASLEQTHIFVLAHILRRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYTRWKDWESWYSQSFGLHFSLREEQWQEDWAFILSLASQPGASLEQTHIFVLAHILRRP
160 170 180 190 200 210
540 550 560 570 580 590
pF1KE0 IIVYGVKYYKSFRGETLGYTRFQGVYLPLLWEQSFCWKSPIALGYTRGHFSALVAMENDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIVYGVKYYKSFRGETLGYTRFQGVYLPLLWEQSFCWKSPIALGYTRGHFSALVAMENDG
220 230 240 250 260 270
600 610 620 630 640 650
pF1KE0 YGNRGAGANLNTDDDVTITFLPLVDSERKLLHVHFLSAQELGNEEQQEKLLREWLDCCVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGNRGAGANLNTDDDVTITFLPLVDSERKLLHVHFLSAQELGNEEQQEKLLREWLDCCVT
280 290 300 310 320 330
660 670 680 690 700
pF1KE0 EGGVLVAMQKSSRRRNHPLVTQMVEKWLDRYRQIRPCTSLSDGEEDEDDEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGGVLVAMQKSSRRRNHPLVTQMVEKWLDRYRQIRPCTSLSDGEEDEDDEDE
340 350 360 370 380
>>XP_011538189 (OMIM: 611749) PREDICTED: ubiquitin thioe (248 aa)
initn: 1610 init1: 1610 opt: 1610 Z-score: 1760.7 bits: 334.8 E(85289): 2.5e-91
Smith-Waterman score: 1610; 100.0% identity (100.0% similar) in 232 aa overlap (477-708:17-248)
450 460 470 480 490 500
pF1KE0 SVLQATWGIYDKDSVLRKALHDSLHDCSHWFYTRWKDWESWYSQSFGLHFSLREEQWQED
::::::::::::::::::::::::::::::
XP_011 MNTRNISHLLFIQVIKFYTRWKDWESWYSQSFGLHFSLREEQWQED
10 20 30 40
510 520 530 540 550 560
pF1KE0 WAFILSLASQPGASLEQTHIFVLAHILRRPIIVYGVKYYKSFRGETLGYTRFQGVYLPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WAFILSLASQPGASLEQTHIFVLAHILRRPIIVYGVKYYKSFRGETLGYTRFQGVYLPLL
50 60 70 80 90 100
570 580 590 600 610 620
pF1KE0 WEQSFCWKSPIALGYTRGHFSALVAMENDGYGNRGAGANLNTDDDVTITFLPLVDSERKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WEQSFCWKSPIALGYTRGHFSALVAMENDGYGNRGAGANLNTDDDVTITFLPLVDSERKL
110 120 130 140 150 160
630 640 650 660 670 680
pF1KE0 LHVHFLSAQELGNEEQQEKLLREWLDCCVTEGGVLVAMQKSSRRRNHPLVTQMVEKWLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHVHFLSAQELGNEEQQEKLLREWLDCCVTEGGVLVAMQKSSRRRNHPLVTQMVEKWLDR
170 180 190 200 210 220
690 700
pF1KE0 YRQIRPCTSLSDGEEDEDDEDE
::::::::::::::::::::::
XP_011 YRQIRPCTSLSDGEEDEDDEDE
230 240
>>XP_011534398 (OMIM: 191163,616744) PREDICTED: tumor ne (689 aa)
initn: 349 init1: 122 opt: 267 Z-score: 290.1 bits: 64.2 E(85289): 2e-09
Smith-Waterman score: 470; 35.7% identity (59.9% similar) in 277 aa overlap (392-651:58-307)
370 380 390 400 410 420
pF1KE0 SLHQRKGDFACYFLTDLVTFTLPADIEDLPPTVQEKLFDEVLDRDVQKELEEESPIINWS
: .: . ..::..: :: .. . ::
XP_011 DIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKL-NWC
30 40 50 60 70 80
430 440 450 460 470 480
pF1KE0 LELATRLDSRLYALWNRTAGDCLLDSVLQATWGIYDKDSVLRKALHDSLHDC-SHWFYTR
:. .: :: . :.::. .. : ::. : : :::::: ..:.. .. : :
XP_011 REV-----RKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFR
90 100 110 120 130 140
490 500 510 520
pF1KE0 WKDWESWYSQSF---GLHFSLREEQWQEDWAFILSLASQ--PGA-------SLEQTHIFV
:. :: :: : :: .. :. :...: ....:: : : :::. ::::
XP_011 WQ-LESLKSQEFVETGLCYDTRN--WNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFV
150 160 170 180 190
530 540 550 560 570 580
pF1KE0 LAHILRRPIIVYGVKYYKSFR-GETLGYTRFQGVYLPLLWEQSFCWKSPIALGYTRGHFS
: .:::::::: . :. .:.. : ... . :.:::: : . :.. ::.::: ::
XP_011 LCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSHHFV
200 210 220 230 240 250
590 600 610 620 630 640
pF1KE0 ALVAMENDGYGNRGAGANLNTDDDVTITFLPLVDSER---KLLHVHFLSAQELGNEEQQE
::.....: :. .:::. .: . :.::::. : .:..:
XP_011 PLVTLKDSGPEIRA---------------VPLVNRDRGRFEDLKVHFLTDPE---NEMKE
260 270 280 290 300
650 660 670 680 690 700
pF1KE0 KLLREWLDCCVTEGGVLVAMQKSSRRRNHPLVTQMVEKWLDRYRQIRPCTSLSDGEEDED
:::.:.:
XP_011 KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
310 320 330 340 350 360
>>NP_001257437 (OMIM: 191163,616744) tumor necrosis fact (790 aa)
initn: 345 init1: 122 opt: 267 Z-score: 289.4 bits: 64.2 E(85289): 2.2e-09
Smith-Waterman score: 470; 35.7% identity (59.9% similar) in 277 aa overlap (392-651:58-307)
370 380 390 400 410 420
pF1KE0 SLHQRKGDFACYFLTDLVTFTLPADIEDLPPTVQEKLFDEVLDRDVQKELEEESPIINWS
: .: . ..::..: :: .. . ::
NP_001 DIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKL-NWC
30 40 50 60 70 80
430 440 450 460 470 480
pF1KE0 LELATRLDSRLYALWNRTAGDCLLDSVLQATWGIYDKDSVLRKALHDSLHDC-SHWFYTR
:. .: :: . :.::. .. : ::. : : :::::: ..:.. .. : :
NP_001 REV-----RKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFR
90 100 110 120 130 140
490 500 510 520
pF1KE0 WKDWESWYSQSF---GLHFSLREEQWQEDWAFILSLASQ--PGA-------SLEQTHIFV
:. :: :: : :: .. :. :...: ....:: : : :::. ::::
NP_001 WQ-LESLKSQEFVETGLCYDTRN--WNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFV
150 160 170 180 190
530 540 550 560 570 580
pF1KE0 LAHILRRPIIVYGVKYYKSFR-GETLGYTRFQGVYLPLLWEQSFCWKSPIALGYTRGHFS
: .:::::::: . :. .:.. : ... . :.:::: : . :.. ::.::: ::
NP_001 LCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSHHFV
200 210 220 230 240 250
590 600 610 620 630 640
pF1KE0 ALVAMENDGYGNRGAGANLNTDDDVTITFLPLVDSER---KLLHVHFLSAQELGNEEQQE
::.....: :. .:::. .: . :.::::. : .:..:
NP_001 PLVTLKDSGPEIRA---------------VPLVNRDRGRFEDLKVHFLTDPE---NEMKE
260 270 280 290 300
650 660 670 680 690 700
pF1KE0 KLLREWLDCCVTEGGVLVAMQKSSRRRNHPLVTQMVEKWLDRYRQIRPCTSLSDGEEDED
:::.:.:
NP_001 KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
310 320 330 340 350 360
>>NP_006281 (OMIM: 191163,616744) tumor necrosis factor (790 aa)
initn: 345 init1: 122 opt: 267 Z-score: 289.4 bits: 64.2 E(85289): 2.2e-09
Smith-Waterman score: 470; 35.7% identity (59.9% similar) in 277 aa overlap (392-651:58-307)
370 380 390 400 410 420
pF1KE0 SLHQRKGDFACYFLTDLVTFTLPADIEDLPPTVQEKLFDEVLDRDVQKELEEESPIINWS
: .: . ..::..: :: .. . ::
NP_006 DIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKL-NWC
30 40 50 60 70 80
430 440 450 460 470 480
pF1KE0 LELATRLDSRLYALWNRTAGDCLLDSVLQATWGIYDKDSVLRKALHDSLHDC-SHWFYTR
:. .: :: . :.::. .. : ::. : : :::::: ..:.. .. : :
NP_006 REV-----RKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFR
90 100 110 120 130 140
490 500 510 520
pF1KE0 WKDWESWYSQSF---GLHFSLREEQWQEDWAFILSLASQ--PGA-------SLEQTHIFV
:. :: :: : :: .. :. :...: ....:: : : :::. ::::
NP_006 WQ-LESLKSQEFVETGLCYDTRN--WNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFV
150 160 170 180 190
530 540 550 560 570 580
pF1KE0 LAHILRRPIIVYGVKYYKSFR-GETLGYTRFQGVYLPLLWEQSFCWKSPIALGYTRGHFS
: .:::::::: . :. .:.. : ... . :.:::: : . :.. ::.::: ::
NP_006 LCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSHHFV
200 210 220 230 240 250
590 600 610 620 630 640
pF1KE0 ALVAMENDGYGNRGAGANLNTDDDVTITFLPLVDSER---KLLHVHFLSAQELGNEEQQE
::.....: :. .:::. .: . :.::::. : .:..:
NP_006 PLVTLKDSGPEIRA---------------VPLVNRDRGRFEDLKVHFLTDPE---NEMKE
260 270 280 290 300
650 660 670 680 690 700
pF1KE0 KLLREWLDCCVTEGGVLVAMQKSSRRRNHPLVTQMVEKWLDRYRQIRPCTSLSDGEEDED
:::.:.:
NP_006 KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS
310 320 330 340 350 360
708 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:18:40 2016 done: Sun Nov 6 15:18:41 2016
Total Scan time: 9.670 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]