Result of FASTA (omim) for
pFN21AB9759
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9759, 714 aa
1>>>pF1KB9759 714 - 714 aa - 714 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.4365+/-0.000429; mu= -21.5513+/- 0.027
mean_var=636.1800+/-133.359, 0's: 0 Z-trim(125.4): 1542 B-trim: 0 in 0/58
Lambda= 0.050849
statistics sampled from 47178 (49078) to 47178 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.826), E-opt: 0.2 (0.575), width: 16
Scan time: 15.660
The best scores are: opt bits E(85289)
NP_006488 (OMIM: 603825) hypermethylated in cancer ( 714) 4995 381.6 5.6e-105
NP_001091672 (OMIM: 603825) hypermethylated in can ( 733) 4995 381.7 5.8e-105
XP_016884158 (OMIM: 607712) PREDICTED: hypermethyl ( 597) 1566 130.0 2.6e-29
XP_011528309 (OMIM: 607712) PREDICTED: hypermethyl ( 615) 1566 130.0 2.7e-29
XP_011528312 (OMIM: 607712) PREDICTED: hypermethyl ( 615) 1566 130.0 2.7e-29
XP_011528310 (OMIM: 607712) PREDICTED: hypermethyl ( 615) 1566 130.0 2.7e-29
XP_011528311 (OMIM: 607712) PREDICTED: hypermethyl ( 615) 1566 130.0 2.7e-29
NP_055909 (OMIM: 607712) hypermethylated in cancer ( 615) 1566 130.0 2.7e-29
XP_011514157 (OMIM: 614040) PREDICTED: zinc finger ( 846) 461 49.1 8.6e-05
XP_011514158 (OMIM: 614040) PREDICTED: zinc finger ( 846) 461 49.1 8.6e-05
XP_005259428 (OMIM: 610671) PREDICTED: zinc finger (1055) 450 48.4 0.00018
NP_149104 (OMIM: 610671) zinc finger protein 628 [ (1059) 450 48.4 0.00018
XP_016867288 (OMIM: 614040) PREDICTED: zinc finger ( 770) 437 47.3 0.00027
XP_016882236 (OMIM: 165260) PREDICTED: zinc finger ( 327) 422 45.9 0.00031
XP_011525220 (OMIM: 165260) PREDICTED: zinc finger ( 327) 422 45.9 0.00031
XP_016882695 (OMIM: 194550) PREDICTED: myeloid zin ( 450) 424 46.1 0.00035
NP_068735 (OMIM: 194544) zinc finger protein 70 [H ( 446) 423 46.1 0.00037
XP_011525219 (OMIM: 165260) PREDICTED: zinc finger ( 491) 422 46.0 0.00042
NP_001308045 (OMIM: 165260) zinc finger and SCAN d ( 491) 422 46.0 0.00042
XP_006723255 (OMIM: 165260) PREDICTED: zinc finger ( 491) 422 46.0 0.00042
NP_862829 (OMIM: 165260) zinc finger and SCAN doma ( 491) 422 46.0 0.00042
XP_016881641 (OMIM: 604750) PREDICTED: zinc finger ( 502) 421 46.0 0.00045
XP_016881642 (OMIM: 604750) PREDICTED: zinc finger ( 502) 421 46.0 0.00045
NP_003413 (OMIM: 194550) myeloid zinc finger 1 iso ( 734) 424 46.3 0.00051
NP_932172 (OMIM: 194550) myeloid zinc finger 1 iso ( 734) 424 46.3 0.00051
XP_016882744 (OMIM: 606740) PREDICTED: zinc finger ( 349) 413 45.2 0.00051
XP_016882743 (OMIM: 606740) PREDICTED: zinc finger ( 349) 413 45.2 0.00051
XP_016882741 (OMIM: 606740) PREDICTED: zinc finger ( 349) 413 45.2 0.00051
NP_001275691 (OMIM: 606740) zinc finger protein 18 ( 349) 413 45.2 0.00051
NP_001275690 (OMIM: 606740) zinc finger protein 18 ( 349) 413 45.2 0.00051
XP_016882742 (OMIM: 606740) PREDICTED: zinc finger ( 349) 413 45.2 0.00051
XP_016882739 (OMIM: 606740) PREDICTED: zinc finger ( 349) 413 45.2 0.00051
XP_016882745 (OMIM: 606740) PREDICTED: zinc finger ( 349) 413 45.2 0.00051
XP_016882740 (OMIM: 606740) PREDICTED: zinc finger ( 349) 413 45.2 0.00051
NP_001275689 (OMIM: 606740) zinc finger protein 18 ( 349) 413 45.2 0.00051
XP_011525566 (OMIM: 194550) PREDICTED: myeloid zin ( 764) 424 46.3 0.00052
XP_005259261 (OMIM: 194550) PREDICTED: myeloid zin ( 775) 424 46.3 0.00053
XP_016881640 (OMIM: 604750) PREDICTED: zinc finger ( 669) 421 46.1 0.00055
XP_016881639 (OMIM: 604750) PREDICTED: zinc finger ( 688) 421 46.1 0.00056
XP_006723037 (OMIM: 604750) PREDICTED: zinc finger ( 700) 421 46.1 0.00057
NP_001138296 (OMIM: 604750) zinc finger protein 23 ( 700) 421 46.1 0.00057
NP_006621 (OMIM: 604750) zinc finger protein 234 [ ( 700) 421 46.1 0.00057
XP_016881638 (OMIM: 604750) PREDICTED: zinc finger ( 700) 421 46.1 0.00057
XP_005252643 (OMIM: 616085) PREDICTED: zinc finger ( 471) 415 45.5 0.00058
XP_016872107 (OMIM: 616085) PREDICTED: zinc finger ( 471) 415 45.5 0.00058
XP_016872109 (OMIM: 616085) PREDICTED: zinc finger ( 471) 415 45.5 0.00058
XP_016872108 (OMIM: 616085) PREDICTED: zinc finger ( 471) 415 45.5 0.00058
XP_006715927 (OMIM: 614040) PREDICTED: zinc finger ( 636) 418 45.8 0.00062
NP_001311180 (OMIM: 616085) zinc finger protein 37 ( 561) 415 45.6 0.00066
NP_001311177 (OMIM: 616085) zinc finger protein 37 ( 561) 415 45.6 0.00066
>>NP_006488 (OMIM: 603825) hypermethylated in cancer 1 p (714 aa)
initn: 4995 init1: 4995 opt: 4995 Z-score: 2005.6 bits: 381.6 E(85289): 5.6e-105
Smith-Waterman score: 4995; 100.0% identity (100.0% similar) in 714 aa overlap (1-714:1-714)
10 20 30 40 50 60
pF1KB9 MLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSAYLKSLVVHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSAYLKSLVVHD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 NLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPGAEPSLGAVLAAASYLQIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPGAEPSLGAVLAAASYLQIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 DLVALCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAATPVIQACYPSPVGPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DLVALCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAATPVIQACYPSPVGPPPPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 AAEPPSGPEAAVNTHCAELYASGPGPAAALCASERRCSPLCGLDLSKKSPPGSAAPERPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AAEPPSGPEAAVNTHCAELYASGPGPAAALCASERRCSPLCGLDLSKKSPPGSAAPERPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 AERELPPRPDSPPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AERELPPRPDSPPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 GRPDGPSLLYRWMKHEPGLGSYGDELGRERGSPSERCEERGGDAAVSPGGPPLGLAPPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GRPDGPSLLYRWMKHEPGLGSYGDELGRERGSPSERCEERGGDAAVSPGGPPLGLAPPPR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 YPGSLDGPGAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYPCPHLAYGEPESFGDNLYVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YPGSLDGPGAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYPCPHLAYGEPESFGDNLYVC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 IPCGKGFPSSEQLNAHVEAHVEEEEALYGRAEAAEVAAGAAGLGPPFGGGGDKVAGAPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IPCGKGFPSSEQLNAHVEAHVEEEEALYGRAEAAEVAAGAAGLGPPFGGGGDKVAGAPGG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 LGELLRPYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRSHLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LGELLRPYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRSHLG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 LKPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LKPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGGAA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 GAAGALAGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQLSLKQQDKAAAAELLAQTTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GAAGALAGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQLSLKQQDKAAAAELLAQTTH
610 620 630 640 650 660
670 680 690 700 710
pF1KB9 FLHDPKVALESLYPLAKFTAELGLSPDKAAEVLSQGAHLAAGPDGRTIDRFSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FLHDPKVALESLYPLAKFTAELGLSPDKAAEVLSQGAHLAAGPDGRTIDRFSPT
670 680 690 700 710
>>NP_001091672 (OMIM: 603825) hypermethylated in cancer (733 aa)
initn: 4995 init1: 4995 opt: 4995 Z-score: 2005.5 bits: 381.7 E(85289): 5.8e-105
Smith-Waterman score: 4995; 100.0% identity (100.0% similar) in 714 aa overlap (1-714:20-733)
10 20 30 40
pF1KB9 MLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRA
:::::::::::::::::::::::::::::::::::::::::
NP_001 MTFPEADILLKSGECAGQTMLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 HKNVLAASSAYLKSLVVHDNLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HKNVLAASSAYLKSLVVHDNLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB9 GAEPSLGAVLAAASYLQIPDLVALCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAEPSLGAVLAAASYLQIPDLVALCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRA
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB9 ATPVIQACYPSPVGPPPPPAAEPPSGPEAAVNTHCAELYASGPGPAAALCASERRCSPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATPVIQACYPSPVGPPPPPAAEPPSGPEAAVNTHCAELYASGPGPAAALCASERRCSPLC
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB9 GLDLSKKSPPGSAAPERPLAERELPPRPDSPPSAGPAAYKEPPLALPSLPPLPFQKLEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLDLSKKSPPGSAAPERPLAERELPPRPDSPPSAGPAAYKEPPLALPSLPPLPFQKLEEA
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB9 APPSDPFRGGSGSPGPEPPGRPDGPSLLYRWMKHEPGLGSYGDELGRERGSPSERCEERG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APPSDPFRGGSGSPGPEPPGRPDGPSLLYRWMKHEPGLGSYGDELGRERGSPSERCEERG
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB9 GDAAVSPGGPPLGLAPPPRYPGSLDGPGAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDAAVSPGGPPLGLAPPPRYPGSLDGPGAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYP
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB9 CPHLAYGEPESFGDNLYVCIPCGKGFPSSEQLNAHVEAHVEEEEALYGRAEAAEVAAGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPHLAYGEPESFGDNLYVCIPCGKGFPSSEQLNAHVEAHVEEEEALYGRAEAAEVAAGAA
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB9 GLGPPFGGGGDKVAGAPGGLGELLRPYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLGPPFGGGGDKVAGAPGGLGELLRPYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTIC
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB9 GKKFTQRGTMTRHMRSHLGLKPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKKFTQRGTMTRHMRSHLGLKPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKF
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB9 AQQRNLISHMKMHAVGGAAGAAGALAGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQQRNLISHMKMHAVGGAAGAAGALAGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQL
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB9 SLKQQDKAAAAELLAQTTHFLHDPKVALESLYPLAKFTAELGLSPDKAAEVLSQGAHLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLKQQDKAAAAELLAQTTHFLHDPKVALESLYPLAKFTAELGLSPDKAAEVLSQGAHLAA
670 680 690 700 710 720
710
pF1KB9 GPDGRTIDRFSPT
:::::::::::::
NP_001 GPDGRTIDRFSPT
730
>>XP_016884158 (OMIM: 607712) PREDICTED: hypermethylated (597 aa)
initn: 1386 init1: 741 opt: 1566 Z-score: 647.1 bits: 130.0 E(85289): 2.6e-29
Smith-Waterman score: 1629; 47.8% identity (64.8% similar) in 630 aa overlap (1-594:1-593)
10 20 30 40 50 60
pF1KB9 MLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSAYLKSLVVHD
: :: :.::.:::::::.::::::::::::.:.:..:::::::::::: :.::::.::
XP_016 MGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAHKNVLAASSIYFKSLVLHD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 NLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPGAEPSLGAVLAAASYLQIP
::.::: :::: .::. .:::::::.: . . : :::.....:.::::::.:
XP_016 NLINLDTDMVSSTVFQQILDFIYTGKLLPSDQ--------P-AEPNFSTLLTAASYLQLP
70 80 90 100 110
130 140 150 160 170
pF1KB9 DLVALCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAATP-VIQACYPSPV----G
.:.:::...::: :: :.: .: . .::: :. : .: :::: : . : :
XP_016 ELAALCRRKLKRAGKPF-----GSGRAGSTGMGRPPRSQRLSTASVIQARYQGLVDGRKG
120 130 140 150 160
180 190 200 210 220
pF1KB9 PPPPPAAEPPSGPEAAV-----NTHCAELYASGPGPA---AAL--CASERR-----CSPL
: .: . . : .. . . :: :.: :.: :
XP_016 AHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSSTNGSSGGCEQE
170 180 190 200 210 220
230 240 250 260
pF1KB9 CGLDLSKKSPPGSAAPERP---------LAEREL--PPRPDSPPSAGPAAYKEPPLALPS
:::::::::: : : :.. . :: ..:: :. :.:.: : .
XP_016 LGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSE----LGG
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB9 LPPLPFQKLEEAAPPSDPFRGGSGSPGPEPPGRPDGPSLLYRWMKHEPGLGSYGD--ELG
: :.. :: : : . .:: .: . .: :.:: :: . : :
XP_016 TPDEPMD-LEGAE---DNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERREAG
290 300 310 320 330
330 340 350 360 370 380
pF1KB9 RERGSPSERCE---ERGGDAAVSPGGPPLGLAPPPRYPGSLDGPGAGGDGDDYKSSSEET
. :.:. : .: .. .. :. : : : :: . . .. ..: .:. :
XP_016 PKGPCPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEEEENGKDASEDSAQSGSEG
340 350 360 370 380 390
390 400 410 420 430 440
pF1KB9 GSSEDPSPPGGHLEGYPCPHLAYGEPESFGDNLYVCIPCGKGFPSSEQLNAHVEAHVEEE
::.. . . ::: : :.::::::::::.::::::::::::::.:.:::
XP_016 GSGHASAHYMYRQEGY--------ETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEE
400 410 420 430 440 450
450 460 470 480 490 500
pF1KB9 EALYGRAEAAEVAAGAAGLGPPFGGGGDKVAGAPGGLGELLRPYRCASCDKSYKDPATLR
:. . :.: .: : . : : . . .: ::..:. :.:.::::::::
XP_016 --LFIKEEGAY----ETGSGGAEEEAEDLSAPSAAYTAEP-RPFKCSVCEKTYKDPATLR
460 470 480 490 500
510 520 530 540 550 560
pF1KB9 QHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRSHLGLKPFACDACGMRFTRQYRLTEHMR
:::::::::::.::.:::: ::::::::::::::::::::::: ::::::::::::::::
XP_016 QHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMR
510 520 530 540 550 560
570 580 590 600 610 620
pF1KB9 IHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGGAAGAAGALAGLGGLPGVPGPDGKGKL
.::::::::::.:::::.::::::::..::
XP_016 VHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS
570 580 590
>>XP_011528309 (OMIM: 607712) PREDICTED: hypermethylated (615 aa)
initn: 1386 init1: 741 opt: 1566 Z-score: 647.0 bits: 130.0 E(85289): 2.7e-29
Smith-Waterman score: 1629; 47.8% identity (64.8% similar) in 630 aa overlap (1-594:19-611)
10 20 30 40
pF1KB9 MLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAH
: :: :.::.:::::::.::::::::::::.:.:..::::
XP_011 MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 KNVLAASSAYLKSLVVHDNLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPG
:::::::: :.::::.::::.::: :::: .::. .:::::::.: . . :
XP_011 KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQ--------P-
70 80 90 100 110
110 120 130 140 150 160
pF1KB9 AEPSLGAVLAAASYLQIPDLVALCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAA
:::.....:.::::::.:.:.:::...::: :: :.: .: . .::: :. : .
XP_011 AEPNFSTLLTAASYLQLPELAALCRRKLKRAGKPF-----GSGRAGSTGMGRPPRSQRLS
120 130 140 150 160
170 180 190 200
pF1KB9 TP-VIQACYPSPV----GPPPPPAAEPPSGPEAAV-----NTHCAELYASGPGPA---AA
: :::: : . : : : .: . . : .. . . :: :.
XP_011 TASVIQARYQGLVDGRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAG
170 180 190 200 210 220
210 220 230 240 250
pF1KB9 L--CASERR-----CSPLCGLDLSKKSPPGSAAPERP---------LAEREL--PPRPDS
: :.: : :::::::::: : : :.. . :: ..
XP_011 LGGCSSSTNGSSGGCEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASA
230 240 250 260 270 280
260 270 280 290 300 310
pF1KB9 PPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPPGRPDGPSLLYR
:: :. :.:.: : . : :.. :: : : . .:: .: . .
XP_011 PPVANSASYSE----LGGTPDEPMD-LEGAE---DNHLSLLEAPGGQPRKSLRHSTRKKE
290 300 310 320 330
320 330 340 350 360
pF1KB9 WMKHEPGLGSYGD--ELGRERGSPSERCE---ERGGDAAVSPGGPPLGLAPPPRYPGSLD
: :.:: :: . : : . :.:. : .: .. .. :. : : : :: . .
XP_011 WGKKEPVAGSPFERREAGPKGPCPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEE
340 350 360 370 380 390
370 380 390 400 410 420
pF1KB9 GPGAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYPCPHLAYGEPESFGDNLYVCIPCGKG
.. ..: .:. : ::.. . . ::: : :.::::::::::.::
XP_011 EENGKDASEDSAQSGSEGGSGHASAHYMYRQEGY--------ETVSYGDNLYVCIPCAKG
400 410 420 430 440 450
430 440 450 460 470 480
pF1KB9 FPSSEQLNAHVEAHVEEEEALYGRAEAAEVAAGAAGLGPPFGGGGDKVAGAPGGLGELLR
::::::::::::.:.::: :. . :.: .: : . : : . . .: :
XP_011 FPSSEQLNAHVETHTEEE--LFIKEEGAY----ETGSGGAEEEAEDLSAPSAAYTAEP-R
460 470 480 490 500
490 500 510 520 530 540
pF1KB9 PYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRSHLGLKPFAC
:..:. :.:.:::::::::::::::::::.::.:::: ::::::::::::::::::::::
XP_011 PFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFAC
510 520 530 540 550 560
550 560 570 580 590 600
pF1KB9 DACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGGAAGAAGAL
: ::::::::::::::::.::::::::::.:::::.::::::::..::
XP_011 DECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS
570 580 590 600 610
610 620 630 640 650 660
pF1KB9 AGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQLSLKQQDKAAAAELLAQTTHFLHDPK
>>XP_011528312 (OMIM: 607712) PREDICTED: hypermethylated (615 aa)
initn: 1386 init1: 741 opt: 1566 Z-score: 647.0 bits: 130.0 E(85289): 2.7e-29
Smith-Waterman score: 1629; 47.8% identity (64.8% similar) in 630 aa overlap (1-594:19-611)
10 20 30 40
pF1KB9 MLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAH
: :: :.::.:::::::.::::::::::::.:.:..::::
XP_011 MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 KNVLAASSAYLKSLVVHDNLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPG
:::::::: :.::::.::::.::: :::: .::. .:::::::.: . . :
XP_011 KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQ--------P-
70 80 90 100 110
110 120 130 140 150 160
pF1KB9 AEPSLGAVLAAASYLQIPDLVALCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAA
:::.....:.::::::.:.:.:::...::: :: :.: .: . .::: :. : .
XP_011 AEPNFSTLLTAASYLQLPELAALCRRKLKRAGKPF-----GSGRAGSTGMGRPPRSQRLS
120 130 140 150 160
170 180 190 200
pF1KB9 TP-VIQACYPSPV----GPPPPPAAEPPSGPEAAV-----NTHCAELYASGPGPA---AA
: :::: : . : : : .: . . : .. . . :: :.
XP_011 TASVIQARYQGLVDGRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAG
170 180 190 200 210 220
210 220 230 240 250
pF1KB9 L--CASERR-----CSPLCGLDLSKKSPPGSAAPERP---------LAEREL--PPRPDS
: :.: : :::::::::: : : :.. . :: ..
XP_011 LGGCSSSTNGSSGGCEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASA
230 240 250 260 270 280
260 270 280 290 300 310
pF1KB9 PPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPPGRPDGPSLLYR
:: :. :.:.: : . : :.. :: : : . .:: .: . .
XP_011 PPVANSASYSE----LGGTPDEPMD-LEGAE---DNHLSLLEAPGGQPRKSLRHSTRKKE
290 300 310 320 330
320 330 340 350 360
pF1KB9 WMKHEPGLGSYGD--ELGRERGSPSERCE---ERGGDAAVSPGGPPLGLAPPPRYPGSLD
: :.:: :: . : : . :.:. : .: .. .. :. : : : :: . .
XP_011 WGKKEPVAGSPFERREAGPKGPCPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEE
340 350 360 370 380 390
370 380 390 400 410 420
pF1KB9 GPGAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYPCPHLAYGEPESFGDNLYVCIPCGKG
.. ..: .:. : ::.. . . ::: : :.::::::::::.::
XP_011 EENGKDASEDSAQSGSEGGSGHASAHYMYRQEGY--------ETVSYGDNLYVCIPCAKG
400 410 420 430 440 450
430 440 450 460 470 480
pF1KB9 FPSSEQLNAHVEAHVEEEEALYGRAEAAEVAAGAAGLGPPFGGGGDKVAGAPGGLGELLR
::::::::::::.:.::: :. . :.: .: : . : : . . .: :
XP_011 FPSSEQLNAHVETHTEEE--LFIKEEGAY----ETGSGGAEEEAEDLSAPSAAYTAEP-R
460 470 480 490 500
490 500 510 520 530 540
pF1KB9 PYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRSHLGLKPFAC
:..:. :.:.:::::::::::::::::::.::.:::: ::::::::::::::::::::::
XP_011 PFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFAC
510 520 530 540 550 560
550 560 570 580 590 600
pF1KB9 DACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGGAAGAAGAL
: ::::::::::::::::.::::::::::.:::::.::::::::..::
XP_011 DECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS
570 580 590 600 610
610 620 630 640 650 660
pF1KB9 AGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQLSLKQQDKAAAAELLAQTTHFLHDPK
>>XP_011528310 (OMIM: 607712) PREDICTED: hypermethylated (615 aa)
initn: 1386 init1: 741 opt: 1566 Z-score: 647.0 bits: 130.0 E(85289): 2.7e-29
Smith-Waterman score: 1629; 47.8% identity (64.8% similar) in 630 aa overlap (1-594:19-611)
10 20 30 40
pF1KB9 MLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAH
: :: :.::.:::::::.::::::::::::.:.:..::::
XP_011 MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 KNVLAASSAYLKSLVVHDNLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPG
:::::::: :.::::.::::.::: :::: .::. .:::::::.: . . :
XP_011 KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQ--------P-
70 80 90 100 110
110 120 130 140 150 160
pF1KB9 AEPSLGAVLAAASYLQIPDLVALCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAA
:::.....:.::::::.:.:.:::...::: :: :.: .: . .::: :. : .
XP_011 AEPNFSTLLTAASYLQLPELAALCRRKLKRAGKPF-----GSGRAGSTGMGRPPRSQRLS
120 130 140 150 160
170 180 190 200
pF1KB9 TP-VIQACYPSPV----GPPPPPAAEPPSGPEAAV-----NTHCAELYASGPGPA---AA
: :::: : . : : : .: . . : .. . . :: :.
XP_011 TASVIQARYQGLVDGRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAG
170 180 190 200 210 220
210 220 230 240 250
pF1KB9 L--CASERR-----CSPLCGLDLSKKSPPGSAAPERP---------LAEREL--PPRPDS
: :.: : :::::::::: : : :.. . :: ..
XP_011 LGGCSSSTNGSSGGCEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASA
230 240 250 260 270 280
260 270 280 290 300 310
pF1KB9 PPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPPGRPDGPSLLYR
:: :. :.:.: : . : :.. :: : : . .:: .: . .
XP_011 PPVANSASYSE----LGGTPDEPMD-LEGAE---DNHLSLLEAPGGQPRKSLRHSTRKKE
290 300 310 320 330
320 330 340 350 360
pF1KB9 WMKHEPGLGSYGD--ELGRERGSPSERCE---ERGGDAAVSPGGPPLGLAPPPRYPGSLD
: :.:: :: . : : . :.:. : .: .. .. :. : : : :: . .
XP_011 WGKKEPVAGSPFERREAGPKGPCPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEE
340 350 360 370 380 390
370 380 390 400 410 420
pF1KB9 GPGAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYPCPHLAYGEPESFGDNLYVCIPCGKG
.. ..: .:. : ::.. . . ::: : :.::::::::::.::
XP_011 EENGKDASEDSAQSGSEGGSGHASAHYMYRQEGY--------ETVSYGDNLYVCIPCAKG
400 410 420 430 440 450
430 440 450 460 470 480
pF1KB9 FPSSEQLNAHVEAHVEEEEALYGRAEAAEVAAGAAGLGPPFGGGGDKVAGAPGGLGELLR
::::::::::::.:.::: :. . :.: .: : . : : . . .: :
XP_011 FPSSEQLNAHVETHTEEE--LFIKEEGAY----ETGSGGAEEEAEDLSAPSAAYTAEP-R
460 470 480 490 500
490 500 510 520 530 540
pF1KB9 PYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRSHLGLKPFAC
:..:. :.:.:::::::::::::::::::.::.:::: ::::::::::::::::::::::
XP_011 PFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFAC
510 520 530 540 550 560
550 560 570 580 590 600
pF1KB9 DACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGGAAGAAGAL
: ::::::::::::::::.::::::::::.:::::.::::::::..::
XP_011 DECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS
570 580 590 600 610
610 620 630 640 650 660
pF1KB9 AGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQLSLKQQDKAAAAELLAQTTHFLHDPK
>>XP_011528311 (OMIM: 607712) PREDICTED: hypermethylated (615 aa)
initn: 1386 init1: 741 opt: 1566 Z-score: 647.0 bits: 130.0 E(85289): 2.7e-29
Smith-Waterman score: 1629; 47.8% identity (64.8% similar) in 630 aa overlap (1-594:19-611)
10 20 30 40
pF1KB9 MLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAH
: :: :.::.:::::::.::::::::::::.:.:..::::
XP_011 MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 KNVLAASSAYLKSLVVHDNLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPG
:::::::: :.::::.::::.::: :::: .::. .:::::::.: . . :
XP_011 KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQ--------P-
70 80 90 100 110
110 120 130 140 150 160
pF1KB9 AEPSLGAVLAAASYLQIPDLVALCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAA
:::.....:.::::::.:.:.:::...::: :: :.: .: . .::: :. : .
XP_011 AEPNFSTLLTAASYLQLPELAALCRRKLKRAGKPF-----GSGRAGSTGMGRPPRSQRLS
120 130 140 150 160
170 180 190 200
pF1KB9 TP-VIQACYPSPV----GPPPPPAAEPPSGPEAAV-----NTHCAELYASGPGPA---AA
: :::: : . : : : .: . . : .. . . :: :.
XP_011 TASVIQARYQGLVDGRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAG
170 180 190 200 210 220
210 220 230 240 250
pF1KB9 L--CASERR-----CSPLCGLDLSKKSPPGSAAPERP---------LAEREL--PPRPDS
: :.: : :::::::::: : : :.. . :: ..
XP_011 LGGCSSSTNGSSGGCEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASA
230 240 250 260 270 280
260 270 280 290 300 310
pF1KB9 PPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPPGRPDGPSLLYR
:: :. :.:.: : . : :.. :: : : . .:: .: . .
XP_011 PPVANSASYSE----LGGTPDEPMD-LEGAE---DNHLSLLEAPGGQPRKSLRHSTRKKE
290 300 310 320 330
320 330 340 350 360
pF1KB9 WMKHEPGLGSYGD--ELGRERGSPSERCE---ERGGDAAVSPGGPPLGLAPPPRYPGSLD
: :.:: :: . : : . :.:. : .: .. .. :. : : : :: . .
XP_011 WGKKEPVAGSPFERREAGPKGPCPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEE
340 350 360 370 380 390
370 380 390 400 410 420
pF1KB9 GPGAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYPCPHLAYGEPESFGDNLYVCIPCGKG
.. ..: .:. : ::.. . . ::: : :.::::::::::.::
XP_011 EENGKDASEDSAQSGSEGGSGHASAHYMYRQEGY--------ETVSYGDNLYVCIPCAKG
400 410 420 430 440 450
430 440 450 460 470 480
pF1KB9 FPSSEQLNAHVEAHVEEEEALYGRAEAAEVAAGAAGLGPPFGGGGDKVAGAPGGLGELLR
::::::::::::.:.::: :. . :.: .: : . : : . . .: :
XP_011 FPSSEQLNAHVETHTEEE--LFIKEEGAY----ETGSGGAEEEAEDLSAPSAAYTAEP-R
460 470 480 490 500
490 500 510 520 530 540
pF1KB9 PYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRSHLGLKPFAC
:..:. :.:.:::::::::::::::::::.::.:::: ::::::::::::::::::::::
XP_011 PFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFAC
510 520 530 540 550 560
550 560 570 580 590 600
pF1KB9 DACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGGAAGAAGAL
: ::::::::::::::::.::::::::::.:::::.::::::::..::
XP_011 DECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS
570 580 590 600 610
610 620 630 640 650 660
pF1KB9 AGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQLSLKQQDKAAAAELLAQTTHFLHDPK
>>NP_055909 (OMIM: 607712) hypermethylated in cancer 2 p (615 aa)
initn: 1386 init1: 741 opt: 1566 Z-score: 647.0 bits: 130.0 E(85289): 2.7e-29
Smith-Waterman score: 1629; 47.8% identity (64.8% similar) in 630 aa overlap (1-594:19-611)
10 20 30 40
pF1KB9 MLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAH
: :: :.::.:::::::.::::::::::::.:.:..::::
NP_055 MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 KNVLAASSAYLKSLVVHDNLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPG
:::::::: :.::::.::::.::: :::: .::. .:::::::.: . . :
NP_055 KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQ--------P-
70 80 90 100 110
110 120 130 140 150 160
pF1KB9 AEPSLGAVLAAASYLQIPDLVALCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAA
:::.....:.::::::.:.:.:::...::: :: :.: .: . .::: :. : .
NP_055 AEPNFSTLLTAASYLQLPELAALCRRKLKRAGKPF-----GSGRAGSTGMGRPPRSQRLS
120 130 140 150 160
170 180 190 200
pF1KB9 TP-VIQACYPSPV----GPPPPPAAEPPSGPEAAV-----NTHCAELYASGPGPA---AA
: :::: : . : : : .: . . : .. . . :: :.
NP_055 TASVIQARYQGLVDGRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAG
170 180 190 200 210 220
210 220 230 240 250
pF1KB9 L--CASERR-----CSPLCGLDLSKKSPPGSAAPERP---------LAEREL--PPRPDS
: :.: : :::::::::: : : :.. . :: ..
NP_055 LGGCSSSTNGSSGGCEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASA
230 240 250 260 270 280
260 270 280 290 300 310
pF1KB9 PPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPPGRPDGPSLLYR
:: :. :.:.: : . : :.. :: : : . .:: .: . .
NP_055 PPVANSASYSE----LGGTPDEPMD-LEGAE---DNHLSLLEAPGGQPRKSLRHSTRKKE
290 300 310 320 330
320 330 340 350 360
pF1KB9 WMKHEPGLGSYGD--ELGRERGSPSERCE---ERGGDAAVSPGGPPLGLAPPPRYPGSLD
: :.:: :: . : : . :.:. : .: .. .. :. : : : :: . .
NP_055 WGKKEPVAGSPFERREAGPKGPCPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEE
340 350 360 370 380 390
370 380 390 400 410 420
pF1KB9 GPGAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYPCPHLAYGEPESFGDNLYVCIPCGKG
.. ..: .:. : ::.. . . ::: : :.::::::::::.::
NP_055 EENGKDASEDSAQSGSEGGSGHASAHYMYRQEGY--------ETVSYGDNLYVCIPCAKG
400 410 420 430 440 450
430 440 450 460 470 480
pF1KB9 FPSSEQLNAHVEAHVEEEEALYGRAEAAEVAAGAAGLGPPFGGGGDKVAGAPGGLGELLR
::::::::::::.:.::: :. . :.: .: : . : : . . .: :
NP_055 FPSSEQLNAHVETHTEEE--LFIKEEGAY----ETGSGGAEEEAEDLSAPSAAYTAEP-R
460 470 480 490 500
490 500 510 520 530 540
pF1KB9 PYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRSHLGLKPFAC
:..:. :.:.:::::::::::::::::::.::.:::: ::::::::::::::::::::::
NP_055 PFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFAC
510 520 530 540 550 560
550 560 570 580 590 600
pF1KB9 DACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGGAAGAAGAL
: ::::::::::::::::.::::::::::.:::::.::::::::..::
NP_055 DECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS
570 580 590 600 610
610 620 630 640 650 660
pF1KB9 AGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQLSLKQQDKAAAAELLAQTTHFLHDPK
>>XP_011514157 (OMIM: 614040) PREDICTED: zinc finger pro (846 aa)
initn: 407 init1: 407 opt: 461 Z-score: 207.0 bits: 49.1 E(85289): 8.6e-05
Smith-Waterman score: 523; 29.1% identity (46.8% similar) in 506 aa overlap (155-594:41-517)
130 140 150 160 170 180
pF1KB9 LCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAATPVIQACYPSPVGPPPPPAA--
: : .. : . : :: :: :..
XP_011 TPRAVLPRERGAAHPAGTGDLETAAHDSLAPPRHGPSSFPQLLPATPPPVRAPPFPGSSL
20 30 40 50 60 70
190 200 210 220 230
pF1KB9 ----EPPSGPEAAVNTHC-----AELYASGPGPAAALCASERRCSPLCGLDLSKKSPPGS
.:: .: :. . : :. . : : :: : :. .:
XP_011 RGREHPPLAPFPAARVPVLPSLLALLHPLSHHPPLPSPPLPRPELPLPHL-LQARSLRTI
80 90 100 110 120
240 250 260 270 280
pF1KB9 AAPERPLAERELPP-----RPDSPPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPF
. : .: . ::: .: .: : .:. :: ::.:: :.: ::
XP_011 TCPPKPTV---LPPGTPLLKPPAPASPSPVRRGSPPA--PSVPP-PLQA---------PF
130 140 150 160 170
290 300 310 320 330
pF1KB9 RGGSGSPG--PEPPGRPDGPSLLYRWMKHEPGLGSYGDELGRERGS-------PSERCEE
: :: : :: . .: :. . : : . . ..: :. :. : :
XP_011 -PGFDSPRVYPSPPREVSGLSVCQSFRPSAPELQAASAIVSRAGGAGGPGAWVPAARAE-
180 190 200 210 220 230
340 350 360 370 380
pF1KB9 RGGDAAVSPGGPP----------------LGLA--PPPRYPGSLDGPGAGGDGDDYKSSS
: .. .. : ::.. : : : :. . ....::
XP_011 RPASQVLWPDPQEELLWVTMRETLEALSSLGFSVGQPEMAPQSEPREGSHNAQEQMSSSR
240 250 260 270 280 290
390 400 410 420 430
pF1KB9 EETG-----SSEDPSPP-GGHLEGYPCPHLAYGEPESFGDNLYVCIPCGKGFPSSEQLNA
:: . . : :.: :.: : : :. : : : :. : .
XP_011 EERALGVCSGHEAPTPEEGAHTEQAEAP--CRGQACSAQKAQ----PVGT-CPGEEWMIR
300 310 320 330 340
440 450 460 470 480
pF1KB9 HVEAHVEEEEALYGRAEAAEVAAGAAGLGPPFGGG--GDKVA------GAPGGLGELL--
.:... :..:: : .: . : :: . : .: ::::.:. :
XP_011 KVKVEDEDQEA----EEEVEWPQHLSLLPSPFPAPDLGHLAAAYKLEPGAPGALSGLALS
350 360 370 380 390 400
490 500 510 520 530
pF1KB9 -------RPYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRSH
.:: :. :.. ..: ::: :.. : : : ::..::::. : :.:::
XP_011 GWGPMPEKPYGCGECERRFRDQLTLRLHQRLHRGEGPCACPDCGRSFTQRAHMLLHQRSH
410 420 430 440 450 460
540 550 560 570 580 590
pF1KB9 LGLKPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGG
: .:: :. : ::... .::.:.: :.::.:: : :: .:.:. .: ::.: :
XP_011 RGERPFPCSECDKRFSKKAHLTRHLRTHTGERPYPCAECGKRFSQKIHLGSHQKTHTGER
470 480 490 500 510 520
600 610 620 630 640 650
pF1KB9 AAGAAGALAGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQLSLKQQDKAAAAELLAQT
XP_011 PFPCTECEKRFRKKTHLIRHQRIHTGERPYQCAQCARSFTHKQHLVRHQRVHQTAGPARP
530 540 550 560 570 580
>>XP_011514158 (OMIM: 614040) PREDICTED: zinc finger pro (846 aa)
initn: 407 init1: 407 opt: 461 Z-score: 207.0 bits: 49.1 E(85289): 8.6e-05
Smith-Waterman score: 523; 29.1% identity (46.8% similar) in 506 aa overlap (155-594:41-517)
130 140 150 160 170 180
pF1KB9 LCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAATPVIQACYPSPVGPPPPPAA--
: : .. : . : :: :: :..
XP_011 TPRAVLPRERGAAHPAGTGDLETAAHDSLAPPRHGPSSFPQLLPATPPPVRAPPFPGSSL
20 30 40 50 60 70
190 200 210 220 230
pF1KB9 ----EPPSGPEAAVNTHC-----AELYASGPGPAAALCASERRCSPLCGLDLSKKSPPGS
.:: .: :. . : :. . : : :: : :. .:
XP_011 RGREHPPLAPFPAARVPVLPSLLALLHPLSHHPPLPSPPLPRPELPLPHL-LQARSLRTI
80 90 100 110 120
240 250 260 270 280
pF1KB9 AAPERPLAERELPP-----RPDSPPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPF
. : .: . ::: .: .: : .:. :: ::.:: :.: ::
XP_011 TCPPKPTV---LPPGTPLLKPPAPASPSPVRRGSPPA--PSVPP-PLQA---------PF
130 140 150 160 170
290 300 310 320 330
pF1KB9 RGGSGSPG--PEPPGRPDGPSLLYRWMKHEPGLGSYGDELGRERGS-------PSERCEE
: :: : :: . .: :. . : : . . ..: :. :. : :
XP_011 -PGFDSPRVYPSPPREVSGLSVCQSFRPSAPELQAASAIVSRAGGAGGPGAWVPAARAE-
180 190 200 210 220 230
340 350 360 370 380
pF1KB9 RGGDAAVSPGGPP----------------LGLA--PPPRYPGSLDGPGAGGDGDDYKSSS
: .. .. : ::.. : : : :. . ....::
XP_011 RPASQVLWPDPQEELLWVTMRETLEALSSLGFSVGQPEMAPQSEPREGSHNAQEQMSSSR
240 250 260 270 280 290
390 400 410 420 430
pF1KB9 EETG-----SSEDPSPP-GGHLEGYPCPHLAYGEPESFGDNLYVCIPCGKGFPSSEQLNA
:: . . : :.: :.: : : :. : : : :. : .
XP_011 EERALGVCSGHEAPTPEEGAHTEQAEAP--CRGQACSAQKAQ----PVGT-CPGEEWMIR
300 310 320 330 340
440 450 460 470 480
pF1KB9 HVEAHVEEEEALYGRAEAAEVAAGAAGLGPPFGGG--GDKVA------GAPGGLGELL--
.:... :..:: : .: . : :: . : .: ::::.:. :
XP_011 KVKVEDEDQEA----EEEVEWPQHLSLLPSPFPAPDLGHLAAAYKLEPGAPGALSGLALS
350 360 370 380 390 400
490 500 510 520 530
pF1KB9 -------RPYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRSH
.:: :. :.. ..: ::: :.. : : : ::..::::. : :.:::
XP_011 GWGPMPEKPYGCGECERRFRDQLTLRLHQRLHRGEGPCACPDCGRSFTQRAHMLLHQRSH
410 420 430 440 450 460
540 550 560 570 580 590
pF1KB9 LGLKPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGG
: .:: :. : ::... .::.:.: :.::.:: : :: .:.:. .: ::.: :
XP_011 RGERPFPCSECDKRFSKKAHLTRHLRTHTGERPYPCAECGKRFSQKIHLGSHQKTHTGER
470 480 490 500 510 520
600 610 620 630 640 650
pF1KB9 AAGAAGALAGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQLSLKQQDKAAAAELLAQT
XP_011 PFPCTECEKRFRKKTHLIRHQRIHTGERPYQCAQCARSFTHKQHLVRHQRVHQTAGPARP
530 540 550 560 570 580
714 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 20:45:09 2016 done: Sun Nov 6 20:45:11 2016
Total Scan time: 15.660 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]