Result of FASTA (omim) for
pFN21AB9752
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9752, 607 aa
1>>>pF1KB9752 607 - 607 aa - 607 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.1092+/-0.000364; mu= 8.9043+/- 0.023
mean_var=207.9438+/-41.521, 0's: 0 Z-trim(120.9): 79 B-trim: 0 in 0/58
Lambda= 0.088941
statistics sampled from 36719 (36800) to 36719 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.431), width: 16
Scan time: 8.680
The best scores are: opt bits E(85289)
NP_001073977 (OMIM: 143100,143400,604613) T-box tr ( 607) 4083 536.6 9e-152
XP_016866961 (OMIM: 143100,143400,604613) PREDICTE ( 449) 3018 399.9 9.9e-111
XP_011534551 (OMIM: 143100,143400,604613) PREDICTE ( 372) 2424 323.6 7.6e-88
XP_016866962 (OMIM: 143100,143400,604613) PREDICTE ( 376) 2424 323.6 7.7e-88
XP_006715665 (OMIM: 143100,143400,604613) PREDICTE ( 364) 2419 322.9 1.2e-87
XP_011534550 (OMIM: 143100,143400,604613) PREDICTE ( 377) 2418 322.8 1.3e-87
XP_011534549 (OMIM: 143100,143400,604613) PREDICTE ( 379) 2416 322.5 1.6e-87
NP_001317606 (OMIM: 260660,604127) T-box transcrip ( 602) 1557 212.5 3.3e-54
NP_689593 (OMIM: 260660,604127) T-box transcriptio ( 496) 1555 212.2 3.5e-54
XP_005271218 (OMIM: 260660,604127) PREDICTED: T-bo ( 635) 1391 191.2 8.9e-48
NP_058650 (OMIM: 300307,302905,303400) T-box trans ( 520) 1210 167.9 7.6e-41
NP_001103348 (OMIM: 300307,302905,303400) T-box tr ( 520) 1210 167.9 7.6e-41
XP_005262193 (OMIM: 300307,302905,303400) PREDICTE ( 521) 1207 167.5 9.9e-41
XP_006724720 (OMIM: 300307,302905,303400) PREDICTE ( 350) 1092 152.6 2.1e-36
XP_011529274 (OMIM: 300307,302905,303400) PREDICTE ( 400) 1044 146.5 1.6e-34
NP_001290404 (OMIM: 300307,302905,303400) T-box tr ( 400) 1044 146.5 1.6e-34
NP_001103349 (OMIM: 300307,302905,303400) T-box tr ( 400) 1044 146.5 1.6e-34
NP_001071121 (OMIM: 606061,611363) T-box transcrip ( 447) 947 134.1 9.8e-31
NP_001159692 (OMIM: 606061,611363) T-box transcrip ( 297) 902 128.2 4e-29
XP_016884414 (OMIM: 187500,188400,192430,217095,60 ( 545) 847 121.4 8.2e-27
NP_542378 (OMIM: 187500,188400,192430,217095,60205 ( 495) 846 121.2 8.4e-27
XP_016884415 (OMIM: 187500,188400,192430,217095,60 ( 495) 846 121.2 8.4e-27
XP_006724375 (OMIM: 187500,188400,192430,217095,60 ( 495) 846 121.2 8.4e-27
XP_016884417 (OMIM: 187500,188400,192430,217095,60 ( 448) 836 119.9 1.9e-26
NP_542377 (OMIM: 187500,188400,192430,217095,60205 ( 398) 835 119.7 1.9e-26
NP_005983 (OMIM: 187500,188400,192430,217095,60205 ( 372) 834 119.5 2e-26
XP_011523792 (OMIM: 147891,601719) PREDICTED: T-bo ( 609) 819 117.8 1.1e-25
XP_011523797 (OMIM: 147891,601719) PREDICTED: T-bo ( 417) 811 116.6 1.7e-25
XP_011523793 (OMIM: 147891,601719) PREDICTED: T-bo ( 608) 812 116.9 2e-25
NP_005986 (OMIM: 604648) T-box transcription facto ( 385) 805 115.8 2.7e-25
XP_011543294 (OMIM: 604648) PREDICTED: T-box trans ( 430) 805 115.9 2.9e-25
XP_016879103 (OMIM: 122600,602427) PREDICTED: T-bo ( 436) 800 115.2 4.6e-25
NP_004599 (OMIM: 122600,602427) T-box transcriptio ( 436) 800 115.2 4.6e-25
XP_011544228 (OMIM: 122600,602427) PREDICTED: T-bo ( 436) 800 115.2 4.6e-25
XP_005255580 (OMIM: 122600,602427) PREDICTED: T-bo ( 436) 800 115.2 4.6e-25
NP_001308049 (OMIM: 147891,601719) T-box transcrip ( 546) 793 114.4 1e-24
XP_016875401 (OMIM: 142900,601620) PREDICTED: T-bo ( 534) 788 113.8 1.5e-24
NP_060958 (OMIM: 147891,601719) T-box transcriptio ( 545) 786 113.5 1.9e-24
NP_005985 (OMIM: 600747) T-box transcription facto ( 712) 784 113.4 2.7e-24
NP_852259 (OMIM: 142900,601620) T-box transcriptio ( 518) 766 111.0 1.1e-23
NP_000183 (OMIM: 142900,601620) T-box transcriptio ( 518) 766 111.0 1.1e-23
NP_005987 (OMIM: 181450,601621) T-box transcriptio ( 723) 764 110.8 1.6e-23
NP_542448 (OMIM: 142900,601620) T-box transcriptio ( 468) 745 108.2 6.4e-23
XP_016877522 (OMIM: 616061) PREDICTED: MAX gene-as (1439) 687 101.2 2.5e-20
XP_011519703 (OMIM: 616061) PREDICTED: MAX gene-as (1549) 687 101.3 2.7e-20
XP_016877519 (OMIM: 616061) PREDICTED: MAX gene-as (2207) 687 101.4 3.4e-20
NP_001074010 (OMIM: 616061) MAX gene-associated pr (2856) 687 101.5 4.1e-20
XP_005254310 (OMIM: 616061) PREDICTED: MAX gene-as (2906) 687 101.5 4.2e-20
XP_005254309 (OMIM: 616061) PREDICTED: MAX gene-as (2956) 687 101.5 4.2e-20
XP_011519700 (OMIM: 616061) PREDICTED: MAX gene-as (3004) 687 101.5 4.3e-20
>>NP_001073977 (OMIM: 143100,143400,604613) T-box transc (607 aa)
initn: 4083 init1: 4083 opt: 4083 Z-score: 2845.8 bits: 536.6 E(85289): 9e-152
Smith-Waterman score: 4083; 99.8% identity (99.8% similar) in 607 aa overlap (1-607:1-607)
10 20 30 40 50 60
pF1KB9 MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAARAVDDGGCSRGGG
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
NP_001 MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAAGAVDDGGCSRGGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 AGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 SPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 PGIPKQGNASSSTLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNTSQLCSLAPADYSAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGIPKQGNASSSTLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNTSQLCSLAPADYSAC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 ARSGLTLNRYSTSLAETYNRLTNQAGETFAPPRTPSYVGVSSSTSVNMSMGGTDGDTFSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARSGLTLNRYSTSLAETYNRLTNQAGETFAPPRTPSYVGVSSSTSVNMSMGGTDGDTFSC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 PQTSLSMQISGMSPQLQYIMPSPSSNAFATNQTHQGSYNTFRLHSPCALYGYNFSTSPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQTSLSMQISGMSPQLQYIMPSPSSNAFATNQTHQGSYNTFRLHSPCALYGYNFSTSPKL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 AASPEKIVSSQGSFLGSSPSGTMTDRQMLPPVEGVHLLSSGGQQSFFDSRTLGSLTLSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AASPEKIVSSQGSFLGSSPSGTMTDRQMLPPVEGVHLLSSGGQQSFFDSRTLGSLTLSSS
550 560 570 580 590 600
pF1KB9 QVSAHMV
:::::::
NP_001 QVSAHMV
>>XP_016866961 (OMIM: 143100,143400,604613) PREDICTED: T (449 aa)
initn: 3018 init1: 3018 opt: 3018 Z-score: 2108.9 bits: 399.9 E(85289): 9.9e-111
Smith-Waterman score: 3018; 100.0% identity (100.0% similar) in 449 aa overlap (159-607:1-449)
130 140 150 160 170 180
pF1KB9 PGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIA
::::::::::::::::::::::::::::::
XP_016 MIITKAGRRMFPAMRVKISGLDPHQQYYIA
10 20 30
190 200 210 220 230 240
pF1KB9 MDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLT
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB9 NNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETVFTTVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETVFTTVTA
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB9 YQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPGIPKQGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPGIPKQGN
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB9 ASSSTLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNTSQLCSLAPADYSACARSGLTLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASSSTLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNTSQLCSLAPADYSACARSGLTLN
220 230 240 250 260 270
430 440 450 460 470 480
pF1KB9 RYSTSLAETYNRLTNQAGETFAPPRTPSYVGVSSSTSVNMSMGGTDGDTFSCPQTSLSMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYSTSLAETYNRLTNQAGETFAPPRTPSYVGVSSSTSVNMSMGGTDGDTFSCPQTSLSMQ
280 290 300 310 320 330
490 500 510 520 530 540
pF1KB9 ISGMSPQLQYIMPSPSSNAFATNQTHQGSYNTFRLHSPCALYGYNFSTSPKLAASPEKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISGMSPQLQYIMPSPSSNAFATNQTHQGSYNTFRLHSPCALYGYNFSTSPKLAASPEKIV
340 350 360 370 380 390
550 560 570 580 590 600
pF1KB9 SSQGSFLGSSPSGTMTDRQMLPPVEGVHLLSSGGQQSFFDSRTLGSLTLSSSQVSAHMV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSQGSFLGSSPSGTMTDRQMLPPVEGVHLLSSGGQQSFFDSRTLGSLTLSSSQVSAHMV
400 410 420 430 440
>>XP_011534551 (OMIM: 143100,143400,604613) PREDICTED: T (372 aa)
initn: 2424 init1: 2424 opt: 2424 Z-score: 1698.1 bits: 323.6 E(85289): 7.6e-88
Smith-Waterman score: 2424; 99.7% identity (99.7% similar) in 356 aa overlap (12-367:1-356)
10 20 30 40 50 60
pF1KB9 MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAARAVDDGGCSRGGG
:::::::::::::::::::::::::::::::::::: ::::::::::::
XP_011 MLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAAGAVDDGGCSRGGG
10 20 30 40
70 80 90 100 110 120
pF1KB9 AGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKG
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB9 SPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB9 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB9 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB9 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDI
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB9 PGIPKQGNASSSTLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNTSQLCSLAPADYSAC
:::::::
XP_011 PGIPKQGCQRIQALQSQLRCAEC
350 360 370
>>XP_016866962 (OMIM: 143100,143400,604613) PREDICTED: T (376 aa)
initn: 2471 init1: 2424 opt: 2424 Z-score: 1698.0 bits: 323.6 E(85289): 7.7e-88
Smith-Waterman score: 2424; 97.8% identity (99.2% similar) in 363 aa overlap (12-374:1-363)
10 20 30 40 50 60
pF1KB9 MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAARAVDDGGCSRGGG
:::::::::::::::::::::::::::::::::::: ::::::::::::
XP_016 MLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAAGAVDDGGCSRGGG
10 20 30 40
70 80 90 100 110 120
pF1KB9 AGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKG
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB9 SPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB9 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB9 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB9 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDI
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB9 PGIPKQGNASSSTLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNTSQLCSLAPADYSAC
:::::: .. .:..
XP_016 PGIPKQDDTLTSAMTVDNHHDNNWKKS
350 360 370
>>XP_006715665 (OMIM: 143100,143400,604613) PREDICTED: T (364 aa)
initn: 2466 init1: 2419 opt: 2419 Z-score: 1694.7 bits: 322.9 E(85289): 1.2e-87
Smith-Waterman score: 2419; 98.9% identity (99.2% similar) in 359 aa overlap (12-370:1-359)
10 20 30 40 50 60
pF1KB9 MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAARAVDDGGCSRGGG
:::::::::::::::::::::::::::::::::::: ::::::::::::
XP_006 MLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAAGAVDDGGCSRGGG
10 20 30 40
70 80 90 100 110 120
pF1KB9 AGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKG
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB9 SPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB9 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB9 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB9 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDI
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB9 PGIPKQGNASSSTLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNTSQLCSLAPADYSAC
:::::: :.
XP_006 PGIPKQERATIGWNA
350 360
>>XP_011534550 (OMIM: 143100,143400,604613) PREDICTED: T (377 aa)
initn: 2465 init1: 2418 opt: 2418 Z-score: 1693.8 bits: 322.8 E(85289): 1.3e-87
Smith-Waterman score: 2418; 98.6% identity (98.9% similar) in 360 aa overlap (12-371:1-360)
10 20 30 40 50 60
pF1KB9 MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAARAVDDGGCSRGGG
:::::::::::::::::::::::::::::::::::: ::::::::::::
XP_011 MLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAAGAVDDGGCSRGGG
10 20 30 40
70 80 90 100 110 120
pF1KB9 AGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKG
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB9 SPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB9 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB9 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB9 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDI
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB9 PGIPKQGNASSSTLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNTSQLCSLAPADYSAC
:::::: . :
XP_011 PGIPKQDGKHSPQGKNAPKMYSGELGPI
350 360 370
>>XP_011534549 (OMIM: 143100,143400,604613) PREDICTED: T (379 aa)
initn: 2416 init1: 2416 opt: 2416 Z-score: 1692.4 bits: 322.5 E(85289): 1.6e-87
Smith-Waterman score: 2416; 99.7% identity (99.7% similar) in 355 aa overlap (12-366:1-355)
10 20 30 40 50 60
pF1KB9 MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAARAVDDGGCSRGGG
:::::::::::::::::::::::::::::::::::: ::::::::::::
XP_011 MLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAAGAVDDGGCSRGGG
10 20 30 40
70 80 90 100 110 120
pF1KB9 AGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKG
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB9 SPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB9 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB9 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB9 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDI
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB9 PGIPKQGNASSSTLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNTSQLCSLAPADYSAC
::::::
XP_011 PGIPKQEYRDLKTDYIFPERDNLVSRETKL
350 360 370
>>NP_001317606 (OMIM: 260660,604127) T-box transcription (602 aa)
initn: 1866 init1: 1405 opt: 1557 Z-score: 1094.1 bits: 212.5 E(85289): 3.3e-54
Smith-Waterman score: 1991; 55.2% identity (73.7% similar) in 636 aa overlap (1-607:1-602)
10 20 30 40 50 60
pF1KB9 MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAARAVDDGGCSRGGG
:.:.::.. :: .:::::::::::..:...:. ..: : . . .:.. .: :
NP_001 MSERRRSA--VALSSRAHAFSVEALIGSNKKRKLRDWEEK-GLDLSMEALSPAG---PLG
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 AGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKG
: ....: : : : . : . : . :: . : .:. . ::: ...:
NP_001 DTEDAAAHGLE----PHPDSEQSTGSDSEVLTERTS---C--SFSTH-TDLASGAAGP--
60 70 80 90 100
130 140 150 160 170 180
pF1KB9 SPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLD
:: . : . .:.:: :.::::::.::::::::::::::::::::::.:::
NP_001 VPA--------AMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLD
110 120 130 140 150
190 200 210 220 230 240
pF1KB9 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVI
:::::::::::::::::::::::::::::::::::::::::::::::: :::.::::::.
NP_001 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB9 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPE
:::::::::::::::::::::::::::::::::::: ..:::: :::: :.:::.:.:::
NP_001 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB9 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDI
::::::::::::::::::::::::::::::::::: ::::..:.:::::: .:::::::.
NP_001 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDF
280 290 300 310 320 330
370 380 390 400 410
pF1KB9 PGIPKQ--GNASSSTLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNT-------SQLCS
. :: :....: ..::. :.. :::: ::: :.:::.::: ::::.
NP_001 TTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLS-PSCSPPTFHLAPNTFNVGCRESQLCN
340 350 360 370 380 390
420 430 440 450 460
pF1KB9 LAPADYSACARSGLTLNRYSTSLAET-YNRLTN------QAGETFAPPRTPSYV-GVSSS
: .:: ::::... . .:... :::: . : .::: : :::: . :. .
NP_001 LNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTTSATQPSETFMPQRTPSLISGIPTP
400 410 420 430 440 450
470 480 490 500 510
pF1KB9 TSV--NMSM---GGTDGDTFSCPQTSLSMQISGMSPQLQYIMPSPSSNAFATNQTHQGSY
:. : .: :: : .: : . :: .. . . : : . :. .. .:.::
NP_001 PSLPGNSKMEAYGGQLG-SFPTSQFQYVMQAGNAASS------SSSPHMFGGSHMQQSSY
460 470 480 490 500
520 530 540 550 560 570
pF1KB9 NTFRLHSPCALYGYNFSTSPKLAASPEKIVSSQGSFLGSSPS-GTMTDRQMLPP-VE-GV
:.: ::.: :::::: :::.:::::::. .::...: :::: :.. .::.:: .: ..
NP_001 NAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPSGMEHSM
510 520 530 540 550 560
580 590 600
pF1KB9 HLLSSG--GQQSF--FDSRTLGSLTLSSSQVSAHMV
:..: . .::. :.: :.. ::::.:.:::
NP_001 HMISPSPNNQQATNTCDGRQYGAVPGSSSQMSVHMV
570 580 590 600
>>NP_689593 (OMIM: 260660,604127) T-box transcription fa (496 aa)
initn: 1758 init1: 1405 opt: 1555 Z-score: 1093.8 bits: 212.2 E(85289): 3.5e-54
Smith-Waterman score: 1897; 61.5% identity (78.4% similar) in 504 aa overlap (133-607:1-496)
110 120 130 140 150 160
pF1KB9 GFQQGASPLASPGGSPKGSPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIIT
. : . .:.:: :.::::::.::::::::
NP_689 MSSMEEIQVELQCADLWKRFHDIGTEMIIT
10 20 30
170 180 190 200 210 220
pF1KB9 KAGRRMFPAMRVKISGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRV
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
NP_689 KAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRV
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB9 YIHPDSPASGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLS
:::::: :::.::::::.:::::::::::::::::::::::::::::::::::: ..:::
NP_689 YIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLS
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB9 PIKPVPSGEGVKAFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALV
: :::: :.:::.:.:::::::::::::::::::::::::::::::::::::: ::::..
NP_689 PTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIM
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB9 ESYAFWRPSLRTLTFEDIPGIPKQ--GNASSSTLLQGTGNGVPATHPHLLSGSSCSSPAF
:.:::::: .:::::::. . :: :....: ..::. :.. :::: ::: :.:
NP_689 ETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLS-PSCSPPTF
220 230 240 250 260
410 420 430 440
pF1KB9 HLGPNT-------SQLCSLAPADYSACARSGLTLNRYSTSLAET-YNRLTN------QAG
::.::: ::::.: .:: ::::... . .:... :::: . : .
NP_689 HLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTTSATQPS
270 280 290 300 310 320
450 460 470 480 490 500
pF1KB9 ETFAPPRTPSYV-GVSSSTSV--NMSM---GGTDGDTFSCPQTSLSMQISGMSPQLQYIM
::: : :::: . :. . :. : .: :: : .: : . :: .. . .
NP_689 ETFMPQRTPSLISGIPTPPSLPGNSKMEAYGGQLG-SFPTSQFQYVMQAGNAASS-----
330 340 350 360 370 380
510 520 530 540 550 560
pF1KB9 PSPSSNAFATNQTHQGSYNTFRLHSPCALYGYNFSTSPKLAASPEKIVSSQGSFLGSSPS
: : . :. .. .:.:::.: ::.: :::::: :::.:::::::. .::...: ::::
NP_689 -SSSPHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPS
390 400 410 420 430 440
570 580 590 600
pF1KB9 -GTMTDRQMLPP-VE-GVHLLSSG--GQQSF--FDSRTLGSLTLSSSQVSAHMV
:.. .::.:: .: ..:..: . .::. :.: :.. ::::.:.:::
NP_689 NGAFGERQYLPSGMEHSMHMISPSPNNQQATNTCDGRQYGAVPGSSSQMSVHMV
450 460 470 480 490
>>XP_005271218 (OMIM: 260660,604127) PREDICTED: T-box tr (635 aa)
initn: 1911 init1: 1386 opt: 1391 Z-score: 978.7 bits: 191.2 E(85289): 8.9e-48
Smith-Waterman score: 1875; 53.1% identity (70.3% similar) in 637 aa overlap (1-579:1-603)
10 20 30 40 50 60
pF1KB9 MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAARAVDDGGCSRGGG
:.:.::.. :: .:::::::::::..:...:. ..: : . . .:.. .: :
XP_005 MSERRRSA--VALSSRAHAFSVEALIGSNKKRKLRDWEEK-GLDLSMEALSPAG---PLG
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 AGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKG
: ....: : : : . : . : . :: . : .:. . ::: ...:
XP_005 DTEDAAAHGLE----PHPDSEQSTGSDSEVLTERTS---C--SFSTH-TDLASGAAGP--
60 70 80 90 100
130 140 150 160 170 180
pF1KB9 SPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLD
:: . : . .:.:: :.::::::.::::::::::::::::::::::.:::
XP_005 VPA--------AMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLD
110 120 130 140 150
190 200 210 220 230 240
pF1KB9 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVI
:::::::::::::::::::::::::::::::::::::::::::::::: :::.::::::.
XP_005 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB9 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPE
:::::::::::::::::::::::::::::::::::: ..:::: :::: :.:::.:.:::
XP_005 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB9 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDI
::::::::::::::::::::::::::::::::::: ::::..:.:::::: .:::::::.
XP_005 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDF
280 290 300 310 320 330
370 380
pF1KB9 PGIPKQ-----------------------------------GNASSSTLLQGTGNGVPAT
. :: :....: ..::. :..
XP_005 TTMQKQQASKKTSQGYTVNQHSSETDAIELYERRVWLMERRGSTGTSPTTSSTGTPSPSA
340 350 360 370 380 390
390 400 410 420 430
pF1KB9 HPHLLSGSSCSSPAFHLGPNT-------SQLCSLAPADYSACARSGLTLNRYSTSLAET-
:::: ::: :.:::.::: ::::.: .:: ::::... . .:...
XP_005 SSHLLS-PSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSG
400 410 420 430 440 450
440 450 460 470 480
pF1KB9 YNRLTN------QAGETFAPPRTPSYV-GVSSSTSV--NMSM---GGTDGDTFSCPQTSL
:::: . : .::: : :::: . :. . :. : .: :: : .: : .
XP_005 YNRLQSGTTSATQPSETFMPQRTPSLISGIPTPPSLPGNSKMEAYGGQLG-SFPTSQFQY
460 470 480 490 500 510
490 500 510 520 530 540
pF1KB9 SMQISGMSPQLQYIMPSPSSNAFATNQTHQGSYNTFRLHSPCALYGYNFSTSPKLAASPE
:: .. . . : : . :. .. .:.:::.: ::.: :::::: :::.::::::
XP_005 VMQAGNAASS------SSSPHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPE
520 530 540 550 560
550 560 570 580 590 600
pF1KB9 KIVSSQGSFLGSSPS-GTMTDRQMLPP-VE-GVHLLSSGGQQSFFDSRTLGSLTLSSSQV
:. .::...: :::: :.. .::.:: .: ..:..:
XP_005 KLSASQSTLLCSSPSNGAFGERQYLPSGMEHSMHMISPSPNNQQATNTCDGRQYGAVPGS
570 580 590 600 610 620
pF1KB9 SAHMV
XP_005 SSQMSVHMV
630
607 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:10:01 2016 done: Mon Nov 7 17:10:02 2016
Total Scan time: 8.680 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]