FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9715, 392 aa
  1>>>pF1KB9715 392 - 392 aa - 392 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.6417+/-0.000423; mu= -6.3236+/- 0.027
 mean_var=579.3323+/-118.381, 0's: 0 Z-trim(126.3): 32  B-trim: 1016 in 1/61
 Lambda= 0.053286
 statistics sampled from 51953 (52018) to 51953 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.84), E-opt: 0.2 (0.61), width:  16
 Scan time: 10.180

The best scores are:                                      opt bits E(85289)
NP_001417 (OMIM: 131290) homeobox protein engraile ( 392) 2686 220.4 5.9e-57
NP_001418 (OMIM: 131310) homeobox protein engraile ( 333)  774 73.3 9.4e-13


>>NP_001417 (OMIM: 131290) homeobox protein engrailed-1   (392 aa)
 initn: 2686 init1: 2686 opt: 2686  Z-score: 1143.5  bits: 220.4 E(85289): 5.9e-57
Smith-Waterman score: 2686; 100.0% identity (100.0% similar) in 392 aa overlap (1-392:1-392)

               10        20        30        40        50        60
pF1KB9 MEEQQPEPKSQRDSALGAAAAATPGGLSLSLSPGASGSSGSGSDGDSVPVSPQPAPPSPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEEQQPEPKSQRDSALGAAAAATPGGLSLSLSPGASGSSGSGSDGDSVPVSPQPAPPSPP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 AAPCLPPLAHHPHLPPHPPPPPPQHLAAPAHQPQPAAQLHRTTNFFIDNILRPDFGCKKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAPCLPPLAHHPHLPPHPPPPPPQHLAAPAHQPQPAAQLHRTTNFFIDNILRPDFGCKKE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 QPPPQLLVAAAARGGAGGGGRVERDRGQTAAGRDPVHPLGTRAPGAASLLCAPDANCGPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPPPQLLVAAAARGGAGGGGRVERDRGQTAAGRDPVHPLGTRAPGAASLLCAPDANCGPP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 DGSQPAAAGAGASKAGNPAAAAAAAAAAVAAAAAAAAAKPSDTGGGGSGGGAGSPGAQGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGSQPAAAGAGASKAGNPAAAAAAAAAAVAAAAAAAAAKPSDTGGGGSGGGAGSPGAQGT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 KYPEHGNPAILLMGSANGGPVVKTDSQQPLVWPAWVYCTRYSDRPSSGPRTRKLKKKKNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYPEHGNPAILLMGSANGGPVVKTDSQQPLVWPAWVYCTRYSDRPSSGPRTRKLKKKKNE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 KEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKK
              310       320       330       340       350       360

              370       380       390  
pF1KB9 ATGIKNGLALHLMAQGLYNHSTTTVQDKDESE
       ::::::::::::::::::::::::::::::::
NP_001 ATGIKNGLALHLMAQGLYNHSTTTVQDKDESE
              370       380       390  

>>NP_001418 (OMIM: 131310) homeobox protein engrailed-2   (333 aa)
 initn: 897 init1: 740 opt: 774  Z-score: 350.0  bits: 73.3 E(85289): 9.4e-13
Smith-Waterman score: 919; 47.1% identity (62.3% similar) in 395 aa overlap (1-392:1-333)

               10        20        30        40        50        60
pF1KB9 MEEQQPEPKSQRDSALGAAAAATPGGLSLSLSPGASGSSGSGSDGDSVPVSPQPAPPSPP
       :::..:.:        : ::::. :  .   :::.    :::. : :   ::  :  .  
NP_001 MEENDPKP--------GEAAAAVEGQRQPESSPGG----GSGGGGGS---SPGEADTGRR
                       10        20            30           40     

               70        80        90       100       110       120
pF1KB9 AAPCLPPLAHHPHLPPHPPPPPPQHLAAPAHQPQPAAQLHRTTNFFIDNILRPDFGCKKE
        :  :: .                 : ::... .:    :: :::::::::::.:: .:.
NP_001 RALMLPAV-----------------LQAPGNHQHP----HRITNFFIDNILRPEFGRRKD
          50                         60            70        80    

              130        140       150       160       170         
pF1KB9 QPPPQLLVAAAARGGAGG-GGRVERDRGQTAAGRDPVHPLGTRAPGAASLLCAPDANCGP
              ....  ::::: ::    . :  :.: . .   :.: :   .  ::: :. ::
NP_001 AGTCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREP-RQNPPCAPGAG-GP
           90       100       110       120        130       140   

      180        190       200       210       220       230       
pF1KB9 -PD-GSQPAAAGAGASKAGNPAAAAAAAAAAVAAAAAAAAAKPSDTGGGGSGGGAGSPGA
        :  ::.  . : :.::.                         :  ::. .::  :.:  
NP_001 LPAAGSDSPGDGEGGSKTL------------------------SLHGGAKKGGDPGGPLD
            150       160                               170        

       240       250       260       270       280       290       
pF1KB9 QGTKYPEHGNPAILLMGSANGGPVVKTDSQQPLVWPAWVYCTRYSDRPSSGPRTRKLKKK
        . :    :.  . . ...... .  . . ::..:::::::::::::::::::.:: :::
NP_001 GSLKARGLGGGDLSVSSDSDSSQAGANLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKK
      180       190       200       210       220       230        

       300       310       320       330       340       350       
pF1KB9 KNEKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAK
       . .:::::::::::::::::::::::.:::.::::::.::::::::::::::::::::::
NP_001 NPNKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAK
      240       250       260       270       280       290        

       360       370       380       390  
pF1KB9 IKKATGIKNGLALHLMAQGLYNHSTTTVQDKDESE
       :::::: :: ::.:::::::::::::. . :..::
NP_001 IKKATGNKNTLAVHLMAQGLYNHSTTAKEGKSDSE
      300       310       320       330   




392 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 06:08:11 2016 done: Sun Nov  6 06:08:12 2016
 Total Scan time: 10.180 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]